Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 15 70357918 rs16954106 G A rs16954106 4.10E-05 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 15 70357918 rs16954106 G A rs16954106 7.08E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 15 70348304 rs17759112 C T rs17759112 1.40E-05 Urinary metabolites HPOID:0000079 DOID:557 C intron GWASdb_trait 15 70357918 rs16954106 G A rs16954106 4.10E-05 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 15 70357918 rs16954106 G A rs16954106 7.08E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 15 70362560 rs7162712 C T rs7162712 2.50E-05 Urinary metabolites HPOID:0000079 DOID:557 C intron GWASdb_trait 15 70368540 rs2291985 C G rs2291985 2.00E-04 Birth weight HPOID:0004323 DOID:783|DOID:9352|DOID:1287 G intron GWASdb_trait 15 70369378 rs11630316 T C rs11630316 9.00E-06 Cognitive function HPOID:0100543 DOID:1561 T intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000140332.15 TLE3 600190