PTM - CPLM Gene Name UniProt ID Type Position Code SIK1; SIK; SNF1LK P57059 Ubiquitination 151 K SIK1; SIK; SNF1LK P57059 Ubiquitination 164 K SIK1; SIK; SNF1LK P57059 Ubiquitination 584 K SIK1; SIK; SNF1LK P57059 Ubiquitination 175 K SIK1; SIK; SNF1LK P57059 Ubiquitination 88 K SIK1; SIK; SNF1LK P57059 Ubiquitination 597 K SIK1; SIK; SNF1LK P57059 Ubiquitination 42 K SIK1; SIK; SNF1LK P57059 Ubiquitination 604 K SIK1; SIK; SNF1LK P57059 Ubiquitination 50 K SIK1; SIK; SNF1LK P57059 Ubiquitination 35 K

PTM - dbPAF Gene Name UniProt ID Position Type Species SIK1; SIK; SNF1LK P57059 182 T Homo sapiens(Human) SIK1; SIK; SNF1LK P57059 186 S Homo sapiens(Human) SIK1; SIK; SNF1LK P57059 435 S Homo sapiens(Human) SIK1; SIK; SNF1LK P57059 460 T Homo sapiens(Human) SIK1; SIK; SNF1LK P57059 479 T Homo sapiens(Human) SIK1; SIK; SNF1LK P57059 575 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P57059 T32-p Phosphorylation GFYDIERtLGKGNFA P57059 T182-p Phosphorylation KSGEPLStWCGSPPY P57059 S370-p Phosphorylation RPRSSDLsGLEVPQE P57059 S435-p Phosphorylation VFRPRPVsPsSLLDT P57059 S437-p Phosphorylation RPRPVsPsSLLDTAI P57059 T460-p Phosphorylation GLEEEQDtQESLPSS P57059 T473-p Phosphorylation SSTGRRHtLAEVStR P57059 T479-p Phosphorylation HtLAEVStRLSPLTA P57059 S516-p Phosphorylation LTFSASKsPAGLSGT P57059 S534-p Phosphorylation QGLLGACsPVRLASP P57059 S575-p Phosphorylation FQEGRRAsDtSLTQG P57059 T577-p Phosphorylation EGRRAsDtSLTQGLk P57059 S626-p Phosphorylation RASRGGLsPFHAPAQ P57059 S634-p Phosphorylation PFHAPAQsPGLHGGA P57059 S644-p Phosphorylation LHGGAAGsREGWSLL P57059 K20-sm Sumoylation GQGQGQQkPLRVGFY P57059 K584-sm Sumoylation tSLTQGLkAFRQQLR P57059 K604-sm Sumoylation KGFLGLNkIKGLARQ

PTM - dbPTM UniProt ID Position Code Type Resources References P57059 182 T Phosphorylation Swiss-Prot 1010711 14976552;18348280 P57059 186 S Phosphorylation Swiss-Prot 1010711 18348280 P57059 435 S Phosphorylation Swiss-Prot 1010711 19369195 P57059 460 T Phosphorylation Swiss-Prot 1010711 17525332 P57059 479 T Phosphorylation Swiss-Prot 1010711 17525332 P57059 182 T Phosphorylation PhosphoELM.10011 14976552 P57059 435 S Phosphorylation Phosphositeplus.1010730 19369195 P57059 575 S Phosphorylation Phosphositeplus.1010730 19369195;22462548 P57059 182 T Phosphorylation Phosphositeplus.1010730 14976552 P57059 460 T Phosphorylation Phosphositeplus.1010730 17525332 P57059 479 T Phosphorylation Phosphositeplus.1010730 17525332 P57059 460 T Phosphorylation HPRD 9.0 17525332 P57059 479 T Phosphorylation HPRD 9.0 17525332

PTM - HPRD Symbol Position Code Type References SIK1 460 T Phosphorylation 17525332 SIK1 479 T Phosphorylation 17525332

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P57059 182 T 14976552 LKB1 LTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P57059 182 Phosphothreonine; by LKB1 and GSK3-beta 14976552;18348280 P57059 186 Phosphoserine; by autocatalysis 18348280

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 150094 127260 - K Ubiquitination 21987572 150094 127260 - K Ubiquitination 23256157 150094 127260 - K Ubiquitination 21963094