PSEN2
PPI - IID
Symbol 1Symbol 2PMIDDBsEvidence TypeAdipose TissueAdrenal GlandAmygdalaBoneBone MarrowBrainDorsal Root GangliaEyeHeartHindgutHypothalamusKidneyLiverLungLymph NodesMammary GlandMidgutNeuronsOvaryPancreasPituitary GlandPlacentaProstateSalivary GlandSkeletal MuscleSmall IntestineSpleenStomachTestesUterus
PSEN2FAF226186194biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2IFIT521163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2GCDH21163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RAB11A10369872hprd,bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
MGEA5PSEN221163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CEP5521163940biogridexpGGGGG
PSEN2METTL2B11738826hprdexpGGGGGGGGG
CLK1PSEN226496610biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ECSIT21163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
CAPN1PSEN210677567,9852298hprd,biogrid,bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ART326186194biogridexpGGGGGGGGGGGGGGGGG
IFIT3PSEN221163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
IRAK2PSEN218996842innatedbexpGGGGGGGGGGGGGGGGGGG
PSEN2KIF2226496610biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ERGIC326186194biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RHEB21163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2AAMP21163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RNF3221163940biogrid,intactexpG
PSEN2ELAVL121163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2EVI5L21163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ACTG121163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2EXOC621163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SPC2421163940biogridexpG
PSEN2MAST121163940biogrid,intactexpGGGGG
PSEN2TSPAN526186194biogridexpGGGGGGGGGGGGGGGGGGGGGGGG
CSNK1DPSEN29558331,9990034,8972483hprd,bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SRPK1bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PSEN215474363biogrid,i2dexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2DYNC1H121163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
RIOK3PSEN2bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2EID121163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
DNAJB1PSEN221163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
LIPFPSEN221163940biogrid,intactexpGGGGGGG
CHKAPSEN221163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
CSNK1A1PSEN28972483hprd,bciexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2DOCK310854253hprdexpGGGGG
PSEN2PPP5C26496610biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NCLNbciexpGGG
PSEN2PDCD421163940biogrid,intactexpG
PSEN2HPS121163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2FBXL1221163940biogrid,intactexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2DLK126186194biogridexpGGGGGGGGGGGGGGGGGGGGGG
NOS3PSEN221163940biogridexpGGG
ECDPSEN221163940biogridexpGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NOTCH411518718hprdexp, orthoGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NOTCH311518718hprd,bciexp, orthoGGGGGGGGGGGGGGGGGGGGGGGGGG
NOTCH1PSEN211518718, 25402006, 23023127, 21836163hprdexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NCSTN10993067,15474363,12297508, 25402006, 21836163hprd,biogrid,intactexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NOTCH211518718, 21836163hprdexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
FLNAPSEN29437013, 25402006hprd,mint,intact,bciexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN1PSEN221163940,15474363,12471034, 25402006biogrid,intactexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APH1A15474363,12471034,12297508, 25402006, 21836163hprd,biogrid,intactexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
SRIPSEN210748169, 25402006, 21836163hprd,biogrid,mint,intact,bciexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ICAM511719200, 25402006hprd,biogridexp, ortho, predGGGGG
PSEN2PSENEN22074918,12639958,12198112,15474363, 25402006, 21836163hprd,biogridexp, ortho, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APBA112196555, 25402006biogridexp, predGGGGGGGGGGGGGGGGGGGGG
APPPSEN221163940,9223340,10078972, 25402006, 21836163hprd,biogrid,i2d,intact,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CASP89219695,9990034,10069390, 25402006hprd,bciexp, predGGGGGGGGGGGGGGGGGGG
PSEN2TRAF618996842,23707529, 25402006, 23023127innatedb,biogridexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
GFAPPSEN212058025, 25402006biogridexp, predGGGGGGGG
PSEN2BIK25402006, 16082366bciexp, predGGGGG
PSEN2APH1B15474363,12297508, 25402006, 21836163hprd,biogrid,intactexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
FLNBPSEN29437013, 25402006hprd,biogrid,mint,intact,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
CASP3PSEN29219695,9990034,10069390, 25402006hprd,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CSNK2A19558331,9990034,8972483, 21836163hprd,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CTNND210037471, 25402006hprd,i2dexp, predGGGGGGGGGGGGGGGGGG
PSEN2CASP69219695,9990034,10069390, 25402006, 21836163hprdexp, predGGGGGGGGGGGGGGGGGGG
PSEN2CASP925402006bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2KCNIP411847232, 25402006, 21836163hprd,biogridexp, predGGGGGGGGGGGGGGGGGG
CASP1PSEN29219695,9990034,10069390, 25402006hprd,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
APBA3PSEN212196555, 25402006biogridexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
CTNNB1PSEN210037471, 25402006, 21836163hprd,i2d,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2KCNIP311278424,9771752, 25402006, 21836163hprd,biogridexp, predGGGGGGGGGGGGG
PSEN2CIB110366599, 21836163hprd,biogrid,i2d,mint,intact,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BCL2L110446169, 25402006, 21836163hprd,biogrid,mint,intact,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2MCL125402006bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2FHL211001931, 25402006, 21836163hprd,biogrid,mint,intact,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGG
CFLARPSEN29219695,9990034,10069390, 25402006hprd,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APBA212196555, 25402006biogridexp, predGGGGGGG
PSEN2UBQLN116813565,17614368,11076969, 25402006, 21836163hprd,biogrid,mint,intactexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
CASP2PSEN225402006bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CASP79219695,9990034,10069390, 25402006, 21836163hprd,bciexp, predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2METTL2Aortho
PSEN2RYR2orthoGGGGGGGG
PSEN2CALCOCO225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2HOMER123023127predGGGGGGGGGGGGGGGGGGGGG
PSEN2TRAF225402006predGG
PSEN2XIAP25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PFN1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
NF1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
BCL2L11PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
HRKPSEN225402006predGGGG
PSEN2TMED225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
BNIP3LPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CASP12PSEN225402006pred
PSEN2TMPRSS623023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BCAP3125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2FBXO223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
KNG1PSEN225402006predGGG
KLKB1PSEN223023127predGGGGGGGGGGGGGGG
C1SPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
LMNAPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CREM25402006predGGGGGGGGGGGGGGGGGGGGGGG
PSEN2TNS323023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2EPS823023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
VAV1PSEN223023127predGGGGGGGGGGGGGGGGGGGG
ARNTLPSEN221836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2C1RL23023127predGGGGGGGGGGGGGGGGGGGG
CSNK2A2PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
VIMPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
C1RPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2GSK3A25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PKP425402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CFDPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGG
F11PSEN223023127predGGGGGGGGGGGG
SNCAPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGG
CDH1PSEN225402006predGGGGGGGGGGGGGGGGGG
PSEN2PLEKHG223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
EGFPSEN223023127predGGGGGGGG
SLIT2PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
TP53PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CASP1225402006pred
FASPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APLP125402006predGGGGGGGGGG
CTGFPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CELSR123023127predGGGGGGGGGGGG
PTPRFPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APBB225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2DEDD225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2LOC64373325402006pred
TGFBR1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
DFFAPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
TNFRSF10BPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
TMED10PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PROCPSEN223023127predGG
PSEN2RIPK125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2VAV323023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
MAN2B1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2EPB41L523023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2UBE2N23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NLRP125402006predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2DGKD23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RIPK325402006predGGGGGGGGGGGGGGGG
SRP14PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SPTAN125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
TFF1PSEN221836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
RB1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PER1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PTPN3PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
CTNND1PSEN225402006pred
THBS1PSEN223023127predGGGGGGGGGGGGGGGGGGGGG
MASP1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2GAB123023127predGGGGGGGGGGGGGGGGGGGGGGGGG
UCHL1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BAK125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
ITGB1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CASP14PSEN225402006predGGG
SYKPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RYR323023127predGGGGGGGGGGGGGGGGGGGGG
PSEN2TRAF325402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2NOTCH2NL23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2APLP225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PARP1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PLK325402006predGGGGGGGGGGGGGGGGGG
ARPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
RPL10PSEN225402006pred
PSEN2CDON23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2ADRM125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
KLK8PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
ARRB2PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGG
BCL2PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
AKT1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
FGF3PSEN223023127pred
PSEN2NR5A121836163predGGGG
PSEN2MAPK8IP125402006predGGGGGGG
TIMP1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
ZAP70PSEN223023127predGGGGGGGGG
PSEN2PRKDC25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2MAPK1425402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PLATPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
FYNPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2FGD123023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2HLA-B21836163pred
CBLPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2GPR18021836163predGGGGGGGGGGGGGGGGGGGGG
PSEN2ASPH23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BAX25402006, 16082366predGGGGGGGGGGG
THY1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PTGES325402006, 23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
GZMBPSEN225402006predGGGGGGGGG
FGFR1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
APBB1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2IKZF123023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2TTN23023127predGGGGGGGGGGGGGGGGGGGGGGGGG
DEDDPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PLAUPSEN223023127predGGGGGGGGGGGGGGGGGGGGGG
PSEN2BID25402006predGGGGGGGGGGGGGGGGGGGGGGG
PSEN2VASP23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CD27623023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BACE225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
EREGPSEN223023127predG
CST3PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
NCK2PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
FOSPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CASP4PSEN225402006predGGGGGGGGGGGGGGGGGGGGG
PSEN2MYBPH23023127predG
PSEN2FADD25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
LCKPSEN223023127predGGGGGGGGGGGGGGG
TRIOPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2HM1321836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PLEKHA123023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2CDK525402006predGGGGGGGGGGGG
F12PSEN223023127predGGGGGGGGGGGGGGGGGG
ATF6PSEN221836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2IHH23023127predGGGGGGGG
PSEN2GRB225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CLK2PSEN221836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
JUPPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BIRC225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2MIB123023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
WASLPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
TNFRSF10APSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
F7PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGG
FGF2PSEN225402006predGGGGGGGGGGGGGGGGG
ANXA7PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
SH2B2PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
RCVRNPSEN221836163predGG
CLOCKPSEN221836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RAD5125402006predGGGGGGGGGG
PLEKPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2TNFSF1025402006predGGGGGGGGGGGGGGGGGGGGGGGGG
JUNPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2FLNC25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2TNFRSF1923023127predGGGGGGGGGGGGGGGGGGGGGGG
PSEN2MYBPC323023127predGGGGGGGGGGGGGGGGGGGGG
MAP2K7PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BCAR123023127predGGGGGGGGGGGGGGGGGGGGGGGGG
SKIPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
ARF4PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
FGF10PSEN223023127predG
PSEN2BTLA23023127predGGG
PSEN2HERPUD125402006, 21836163predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PLK225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
HCLS1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
APAF1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CD40PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SHC323023127predGGGGGGGGG
SMAD7PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
EGR1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
VDAC1PSEN225402006, 16082366predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SMAD323023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PRKCD23023127predGGGGGGGGGGGGGGGGGGGGGG
PSEN2VAV223023127predGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SQSTM125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
EFEMP2PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2TCF7L225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PTPN1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2SHH23023127predGGGGGGGGGGGGGGGGGGG
PSEN2DNER23023127predGGGGGGGGGGGGGGG
PSEN2CASP525402006pred
PSEN2BMF25402006predGGGGGGGGGGGGGGGGGG
MAPTPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2PACSIN323023127predGGGGGGGGGGGGGGGGGG
PSEN2CARD825402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
SHC1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
BIRC5PSEN225402006predGGGGGGG
PSEN2CBLB23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2BIRC325402006predGGGGGGGGGGGGGGGGG
PSEN2ROR223023127predGGGGGGG
CFIPSEN223023127predGGGGGGGGGGGGGGGGGGGGGG
PSEN2DPF225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
SOCS1PSEN223023127predGGGGGGGGGGGGGGGGGGG
PSEN2FHL325402006predGGGGGGGGGGGGGGGGGGGG
PLCG2PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
EIF2S1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2INPP5D23023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
F2PSEN223023127predG
GCAPSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
CAPNS1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
EPHB2PSEN223023127predGGGGGGGGGGGGGGGGGGG
PSEN2TRAF125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
HSP90AA1PSEN225402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2MTCH125402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2KLK623023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2RPGRIP1L23023127predGGGG
PSEN2CASP1025402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
THBDPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2WNK325402006predGGGGGGGGGGGGGGGG
CRKLPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
PSEN2GSK3B25402006predGGGGGGGGGGGGGGGGGGGGGGGGGG
ELF1PSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
KDRPSEN223023127predGGGGGGGGGGGGGGGGGGGGGGGGGG
SMAD6PSEN223023127predGGGGGGGGGGGGGGGGGGGGGG
PPI - iRefIndex
UniProt AUniProt BMethodPMIDInteraction TypeEdge typeNum Participants
P49810coimmunoprecipitation15286082associationC4
P49810coimmunoprecipitation15286082associationC4
P49810anti tag coimmunoprecipitation12297508associationC3
P49810anti bait coimmunoprecipitation12297508physical associationC4
P49810P62493two hybrid10369872physical associationX2
P49810P62493coimmunoprecipitation10369872physical associationX2
P49810Q9BQ95two hybrid array21163940physical associationX2
P49810A0A024R6A3two hybrid array21163940physical associationX2
P49810Q8TAG9two hybrid array21163940physical associationX2
P49810P25685two hybrid array21163940physical associationX2
P49810P07098two hybrid array21163940physical associationX2
P49810Q14204two hybrid21163940physical associationX2
P49810Q9Y6B2two hybrid21163940physical associationX2
P49810Q9BQ95anti bait coimmunoprecipitation21163940associationX2
P49810Q9BQ95anti bait coimmunoprecipitation21163940associationX2
P49810Q14204anti bait coimmunoprecipitation21163940associationX2
P49810Q14204anti bait coimmunoprecipitation21163940associationX2
P49810Q9BQ95confocal microscopy21163940colocalizationX2
P49810P05067anti bait coimmunoprecipitation9223340physical associationX2
P49810P21333coimmunoprecipitation9437013physical associationX2
P49810O75369coimmunoprecipitation9437013physical associationX2
P49810O75369two hybrid9437013physical associationX2
P49810P21333two hybrid9437013physical associationX2
P49810anti tag coimmunoprecipitation12297508physical associationC3
P49810Q99828pull down10366599direct interactionX2
P49810Q99828two hybrid10366599physical associationX2
P49810Q99828fluorescence microscopy10366599colocalizationX2
P49810Q07817two hybrid10446169physical associationX2
P49810Q07817coimmunoprecipitation10446169physical associationX2
P49810Q07817fluorescence microscopy10446169colocalizationX2
P49810P30626filter binding10748169direct interactionX2
P49810P30626coimmunoprecipitation10748169physical associationX2
P49810Q14192two hybrid11001931physical associationX2
P49810Q14192pull down11001931direct interactionX2
P49810Q14192coimmunoprecipitation11001931physical associationX2
P49810A0A024R284pull down11076969direct interactionX2
P49810A0A024R284two hybrid11076969physical associationX2
P49810A0A024R284fluorescence microscopy11076969colocalizationX2
P49810Q8WW43pull down12297508physical associationX2
P49810Q9Y2H9two hybrid array21163940physical associationX2
P49810A0A090N900two hybrid array21163940physical associationX2
P49810Q53EL6two hybrid array21163940physical associationX2
P49810Q9NXK8two hybrid array21163940physical associationX2
P49810A0A024RD87two hybrid array21163940physical associationX2
P49810Q53EL6anti bait coimmunoprecipitation21163940associationX2
P49810Q53EL6anti bait coimmunoprecipitation21163940associationX2
P49810O35463anti bait coimmunoprecipitation9223340physical associationX2
P49810P05067coimmunoprecipitation10078972-X2
P49810P05067coimmunoprecipitation10078972-X2
P49810P05067coimmunoprecipitation10078972-X2
P49810P05067coimmunoprecipitation10078972-X2
P49810P05067coimmunoprecipitation10078972-X2
P49810Q9UQB3coimmunoprecipitation10037471-X2
P49810P49810coimmunoprecipitation9666482-X2
P49810A0A024R2Q3coimmunoprecipitation10037471-X2
P49810Q99828two hybrid10366599-X2
P49810Q99828two hybrid10366599-X2
P49810Q99828two hybrid10366599-X2
P49810Q99828copurification10366599-X2
P49810Q99828coimmunoprecipitation10366599-X2
P49810Q99828coimmunoprecipitation10366599-X2
PPI - PINA
Gene AGene BMethodPublicationsSpecies ASpecies BInteraction TypeSource DatabaseInteraction IdentidiersExperimental Role(s) Interactor AExperimental Role(s) Interactor B
CHKAPSEN2MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_230014preybait
PSEN2CSNK2A1MI:0492(in vitro)8972483taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_13853--
PSEN2METTL2BMI:0018(two hybrid)11738826taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7687--
FLNBPSEN2MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)9437013taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)(intact)|MI:0468(hprd)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)UniProt_135985|HPRD_7676|BIOGRID_97070|UniProt_135989|MINT_85571|MINT_85572|BIOGRID_97068|MINT_56524|MINT_56523bait|-|bait|bait|bait|bait|prey|bait|baitprey|-|prey|prey|prey|prey|bait|prey|prey
APPPSEN2MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)10078972,21163940,9223340taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0915(physical association)|MI:0407(direct interaction)MI:0468(hprd)|(intact)|(biogrid)HPRD_17287|UniProt_134429|BIOGRID_229896-|prey|bait-|bait|prey
PSEN2PSENENMI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)12198112,15474363taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0915(physical association)|MI:0915(physical association)MI:0468(hprd)|(biogrid)|(biogrid)HPRD_7685|BIOGRID_244430|BIOGRID_105698-|bait|prey-|prey|bait
PSEN2FBXL12MI:0096(pull down)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(intact)|(biogrid)UniProt_111158|BIOGRID_229841bait|baitprey|prey
CASP1PSEN2MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_36531--
UBCPSEN2MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)15004330,17614368,21906983,21963094,23707529taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)BIOGRID_177426|BIOGRID_118104|BIOGRID_225788|BIOGRID_264030|BIOGRID_281237bait|prey|prey|bait|preyprey|bait|bait|prey|bait
PSEN2BCL2L1MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)10446169taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0468(hprd)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)BIOGRID_109348|BIOGRID_109349|MINT_56659|MINT_56658|UniProt_66748|MINT_56657|HPRD_6102|UniProt_66751|UniProt_66750|MINT_85726|MINT_85724|MINT_85725bait|bait|neutral component|prey|prey|prey|-|prey|neutral component|neutral component|prey|preyprey|prey|neutral component|bait|bait|bait|-|bait|neutral component|neutral component|bait|bait
MGEA5PSEN2MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229930preybait
PSEN2HPS1MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_230016baitprey
PSEN2DOCK3MI:0492(in vitro)10854253taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7688--
PSEN2GCDHMI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229927baitprey
PSEN2KCNIP4MI:0493(in vivo)11847232taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7689--
PSEN2NCSTNMI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)10993067,12297508,15474363taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)(intact)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)UniProt_70627|BIOGRID_103229|BIOGRID_244429|HPRD_7680|BIOGRID_104580null|prey|bait|-|preybait|bait|prey|-|bait
GFAPPSEN2MI:0018(two hybrid)12058025taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_95890preybait
PSEN2ECSITMI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)UniProt_110961|UniProt_110960|UniProt_111071|BIOGRID_229754|BIOGRID_230127|UniProt_111184bait|prey|prey|prey|prey|neutral componentprey|bait|bait|bait|bait|neutral component
PSEN2APBA1MI:0004(affinity chromatography technology)12196555taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)(biogrid)BIOGRID_96254baitprey
CASP3PSEN2MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7371--
PSEN2RAB11AMI:0493(in vivo)10369872taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7682--
DNAJB1PSEN2MI:0004(affinity chromatography technology)|MI:0096(pull down)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)(biogrid)|(intact)BIOGRID_229843|UniProt_111160prey|preybait|bait
PSEN2CEP55MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229924baitprey
PSEN2PDCD4MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)(intact)|(intact)|(intact)|(biogrid)|(biogrid)UniProt_110973|UniProt_111157|UniProt_110974|BIOGRID_229840|BIOGRID_230125bait|bait|prey|bait|baitprey|prey|bait|prey|prey
LIPFPSEN2MI:0096(pull down)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(intact)|(biogrid)UniProt_111161|BIOGRID_229844prey|preybait|bait
CSNK1A1PSEN2MI:0492(in vitro)8972483taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7097--
PSEN2CTNND2MI:0493(in vivo)10037471taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7686--
PSEN2UBQLN1MI:0096(pull down)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0096(pull down)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)11076969,16813565,17614368taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0403(colocalization)|-|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)(intact)|(biogrid)|(intact)|(intact)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)UniProt_68862|BIOGRID_103891|UniProt_68860|UniProt_68864|HPRD_7679|MINT_77418|BIOGRID_103889|MINT_77417|MINT_77416|BIOGRID_118103|BIOGRID_118105|MINT_57301|BIOGRID_194381|MINT_57300|MINT_57299prey|prey|prey|neutral component|-|neutral component|prey|prey|prey|bait|prey|neutral component|prey|prey|preybait|bait|bait|neutral component|-|neutral component|bait|bait|bait|prey|bait|neutral component|bait|bait|bait
PSEN2ICAM5MI:0492(in vitro)|MI:0004(affinity chromatography technology)11719200taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0407(direct interaction)MI:0468(hprd)|(biogrid)HPRD_7673|BIOGRID_97732-|bait-|prey
PSEN2NOTCH3MI:0493(in vivo)11518718taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_25341--
CAPN1PSEN2MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)10677567,9852298taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0915(physical association)|MI:0407(direct interaction)MI:0468(hprd)|(biogrid)|(biogrid)HPRD_12511|BIOGRID_101182|BIOGRID_77256-|prey|prey-|bait|bait
IFIT3PSEN2MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229928preybait
PSEN2ACTG1MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_230013baitprey
FLNAPSEN2MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid)9437013taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0468(hprd)|MI:0471(mint)MINT_85463|MINT_56433|MINT_56434|UniProt_135986|UniProt_135991|HPRD_5100|MINT_85464prey|prey|prey|prey|prey|-|preybait|bait|bait|bait|bait|-|bait
PSEN2CASP7MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7671--
PSEN2CASP6MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7669--
PSEN2APH1BMI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)12297508,15474363taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|-|MI:0915(physical association)(biogrid)|MI:0468(hprd)|(intact)BIOGRID_244437|HPRD_7684|UniProt_70630prey|-|nullbait|-|bait
PSEN2CIB1MI:0493(in vivo)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)10366599taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0799(additive genetic interaction defined by inequality)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction)MI:0468(hprd)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)HPRD_7674|UniProt_67331|MINT_85903|BIOGRID_111024|MINT_85901|MINT_85902|UniProt_67330|BIOGRID_111025|BIOGRID_111026|MINT_56805|MINT_56806|MINT_56807|UniProt_67329-|neutral component|bait|bait|bait|neutral component|bait|prey|prey|bait|neutral component|bait|bait-|neutral component|prey|prey|prey|neutral component|prey|bait|bait|prey|neutral component|prey|prey
PSEN2APBA2MI:0004(affinity chromatography technology)12196555taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)(biogrid)BIOGRID_96255baitprey
CTNNB1PSEN2MI:0493(in vivo)10037471taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_17608--
PSEN2AAMPMI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_230012baitprey
PSEN2IFIT5MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229929baitprey
PSEN2NOTCH4MI:0493(in vivo)11518718taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_24961--
PSEN2NOTCH2MI:0493(in vivo)11518718taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_25338--
SRIPSEN2MI:0049(filter binding)|MI:0049(filter binding)|MI:0049(filter binding)|MI:0004(affinity chromatography technology)|MI:0049(filter binding)|MI:0049(filter binding)|MI:0049(filter binding)|MI:0493(in vivo)10748169taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|(intact)|MI:0468(hprd)MINT_77287|MINT_77288|MINT_57179|BIOGRID_103570|MINT_57180|UniProt_67403|UniProt_67402|HPRD_3035bait|bait|bait|prey|bait|bait|bait|-prey|prey|prey|bait|prey|prey|prey|-
NOS3PSEN2MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229913baitprey
PSEN2CASP8MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7672--
PSEN2DYNC1H1MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)(intact)|(biogrid)|(intact)|(biogrid)|(intact)UniProt_110982|BIOGRID_230126|UniProt_110983|BIOGRID_229975|UniProt_111012bait|bait|prey|bait|baitprey|prey|bait|prey|prey
PSEN2SPC24MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229931baitprey
PSEN2FHL2MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)11001931taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)HPRD_7675|MINT_86095|UniProt_69182|BIOGRID_109370|MINT_56974|UniProt_69183|MINT_86094|UniProt_69184|MINT_56973|MINT_56972|MINT_86093|BIOGRID_109369-|prey|prey|bait|prey|prey|prey|prey|prey|prey|prey|bait-|bait|bait|prey|bait|bait|bait|bait|bait|bait|bait|prey
PSEN2RNF32MI:0096(pull down)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(intact)|(biogrid)UniProt_111162|BIOGRID_229845bait|baitprey|prey
CFLARPSEN2MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7677--
PSEN2TRAF6MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)18996842,23707529taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)(biogrid)|(biogrid)|(biogrid)BIOGRID_281235|BIOGRID_281234|BIOGRID_213372bait|prey|preyprey|bait|bait
PSEN2RHEBMI:0096(pull down)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(intact)|(biogrid)UniProt_111156|BIOGRID_229839bait|baitprey|prey
PSEN2EID1MI:0004(affinity chromatography technology)|MI:0096(pull down)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)(biogrid)|(intact)BIOGRID_229976|UniProt_111015bait|baitprey|prey
CSNK1DPSEN2MI:0493(in vivo)9990034taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)-MI:0468(hprd)HPRD_7668--
PSEN2KCNIP3MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)11278424,9771752taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)BIOGRID_77734|BIOGRID_99766|HPRD_7678|BIOGRID_101644|BIOGRID_101645bait|bait|-|bait|preyprey|prey|-|prey|bait
PSEN2MAST1MI:0096(pull down)|MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(intact)|(biogrid)UniProt_111112|BIOGRID_229795prey|preybait|bait
PSEN2ELAVL1MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229925baitprey
PSEN2EVI5LMI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_229926baitprey
PSEN2APH1AMI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)12297508,12471034,15474363taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(intact)BIOGRID_102355|BIOGRID_103225|BIOGRID_244423|BIOGRID_244431|HPRD_7683|UniProt_70629prey|prey|prey|bait|-|-bait|bait|bait|prey|-|-
ECDPSEN2MI:0004(affinity chromatography technology)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)(biogrid)BIOGRID_230015preybait
PSEN2KCNIP4MI:0018(two hybrid)|MI:0018(two hybrid)11847232taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0407(direct interaction)(biogrid)|(biogrid)BIOGRID_110941|BIOGRID_110925bait|baitprey|prey
PSEN1PSEN2MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)12471034,15474363,21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)UniProt_111149|BIOGRID_244432|BIOGRID_229832|BIOGRID_244428|BIOGRID_102352bait|prey|bait|bait|baitprey|bait|prey|prey|prey
APBA3PSEN2MI:0004(affinity chromatography technology)12196555taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0915(physical association)(biogrid)BIOGRID_96256preybait
PSEN2EXOC6MI:0004(affinity chromatography technology)|MI:0096(pull down)21163940taxid:9606(Homo sapiens)taxid:9606(Homo sapiens)MI:0407(direct interaction)|MI:0915(physical association)(biogrid)|(intact)BIOGRID_229842|UniProt_111159bait|baitprey|prey
PPI - HINT
Gene AGene BPMIDMethodQuality
CLK1PSEN226496610,264966100007,0004HT
PSEN1PSEN212471034,154743630004,0004LC
PSEN2PPP5C26496610,264966100007,0004HT
PSEN2TSPAN5261861940004HT
PSEN2DLK1261861940004HT
PSEN2ART3261861940004HT
PSEN2KIF2226496610,264966100007,0004HT
PSEN2APH1B15474363,122975080004,0096LC
PSEN2NCSTN15474363,10993067,12297508,122975080004,0004,0004,0006LC
PSEN2APH1A15474363,12297508,12297508,124710340004,0004,0007,0004LC
PSEN2FAF2261861940004HT
PSEN2PSENEN12198112,22074918,154743630004,0004,0004LC
PSEN2UBQLN116813565,11076969,17614368,11076969,11076969,176143680096,0018,0096,0416,0096,0018LC
PSEN2ERGIC3261861940004HT
PSEN2KCNIP39771752,9771752,112784240004,0018,0004LC
PSEN2TRAF623707529,18996842,189968420004,0004,0007LC
CLK1PSEN226496610,264966100007,0004HT
PSEN2PPP5C26496610,264966100007,0004HT
PSEN2TSPAN5261861940004HT
PSEN2DLK1261861940004HT
PSEN2ART3261861940004HT
PSEN2KIF2226496610,264966100007,0004HT
PSEN2FAF2261861940004HT
PSEN2ERGIC3261861940004HT
PSEN1PSEN212471034,154743630004,0004LC
PSEN2APH1B15474363,122975080004,0096LC
PSEN2NCSTN15474363,10993067,12297508,122975080004,0004,0004,0006LC
PSEN2APH1A15474363,12297508,12297508,124710340004,0004,0007,0004LC
PSEN2PSENEN12198112,22074918,154743630004,0004,0004LC
PSEN2UBQLN116813565,11076969,17614368,11076969,11076969,176143680096,0018,0096,0416,0096,0018LC
PSEN2KCNIP39771752,9771752,112784240004,0018,0004LC
PSEN2TRAF623707529,18996842,189968420004,0004,0007LC
IFIT3PSEN2211639400018HT
MGEA5PSEN2211639400018HT
FLNBPSEN29437013,9437013,94370130019,0018,0096LC
ECDPSEN2211639400018HT
APPPSEN29223340,21163940,9223340,100789720019,0018,0006,0019LC,HT
LIPFPSEN221163940,211639400397,0018HT
CAPN1PSEN29852298,9852298,106775670018,0004,0018LC
GFAPPSEN2120580250018LC
FLNAPSEN29437013,94370130019,0018LC
DNAJB1PSEN221163940,211639400397,0018HT
NOS3PSEN2211639400018HT
SRIPSEN210748169,10748169,107481690019,0049,0004LC
CTNNB1PSEN2100374710019LC
CHKAPSEN2211639400018HT
PSEN1PSEN221163940,211639400397,0018HT
PSEN2PSEN296664820019LC
PSEN2RAB11A103698720018LC
PSEN2ACTG1211639400018HT
PSEN2BCL2L110446169,10446169,10446169,104461690416,0018,0004,0019LC
PSEN2IFIT5211639400018HT
PSEN2AAMP211639400018HT
PSEN2FHL211001931,11001931,11001931,110019310018,0004,0096,0019LC
PSEN2DYNC1H121163940,21163940,211639400006,0004,0018HT
PSEN2RHEB21163940,211639400397,0018HT
PSEN2ELAVL1211639400018HT
PSEN2PDCD421163940,21163940,21163940,211639400397,0006,0004,0018HT
PSEN2CEP55211639400018HT
PSEN2METTL2B117388260018LC
PSEN2KCNIP411847232,118472320004,0018LC
PSEN2DOCK3108542530018LC
PSEN2SPC24211639400018HT
PSEN2EXOC621163940,211639400397,0018HT
PSEN2HPS1211639400018HT
PSEN2GCDH211639400018HT
PSEN2EVI5L211639400018HT
PSEN2CIB110366599,10366599,10366599,10366599,10366599,103665990416,0004,0025,0018,0019,0096LC
PSEN2ECSIT21163940,21163940,21163940,21163940,211639400663,0397,0006,0004,0018HT
PSEN2RNF3221163940,211639400397,0018HT
PSEN2FBXL1221163940,211639400397,0018HT
PSEN2ICAM511719200,117192000096,0018LC
PSEN2UBQLN111076969,17614368,11076969,11076969,176143680018,0096,0416,0096,0018LC
PSEN2CTNND2100374710019LC
PSEN2MAST121163940,211639400397,0018HT
PSEN2KCNIP39771752,97717520004,0018LC
PSEN2EID1211639400018HT
PPI - Mentha
Protein AProtein BGene AGene BScorePMID
P62079P49810TSPAN5PSEN20.12626186194
Q9Y2W7P49810KCNIP3PSEN20.6599771752,11278424
Q9Y282P49810ERGIC3PSEN20.12626186194
P49810P06792PSEN2E50.12622810586
Q8WW43P49810APH1BPSEN20.37612297508,15474363
P49810P05067PSEN2APP0.35421163940,9223340
Q99828P49810CIB1PSEN20.77210366599
Q14192P49810FHL2PSEN20.79411001931
P49810P21333PSEN2FLNA0.4549437013
Q53EL6P49810PDCD4PSEN20.45421163940
P49810P49759PSEN2CLK10.23626496610
P49810O75369PSEN2FLNB0.749437013
P49810P25685PSEN2DNAJB10.28621163940
P49810P07098PSEN2LIPF0.28621163940
P49810P07384PSEN2CAPN10.4549852298
Q6PIL6P49810KCNIP4PSEN20.45411847232
P49810P49768PSEN2PSEN10.64815474363,21163940,12471034
Q15382P49810RHEBPSEN20.28621163940
Q9BQ95P49810ECSITPSEN20.49821163940
Q8TAG9P49810EXOC6PSEN20.28621163940
Q9UMX0P49810UBQLN1PSEN20.93417614368,11076969,16813565
Q9H0A6P49810RNF32PSEN20.28621163940
Q9NXK8P49810FBXL12PSEN20.28621163940
P62493P49810RAB11APSEN20.45410369872
P49810P29474PSEN2NOS30.18321163940
P49810P30626PSEN2SRI0.56910748169
Q96CS3P49810FAF2PSEN20.12626186194
P80370P49810DLK1PSEN20.12626186194
Q14204P49810DYNC1H1PSEN20.4921163940
Q14807P49810KIF22PSEN20.12626496610
P49810O14879PSEN2IFIT30.18321163940
P49810O35463PSEN2BETA APP0.219223340
P49810O60502PSEN2MGEA50.18321163940
P49810O95905PSEN2ECD0.18321163940
P49810O96018PSEN2APBA30.2112196555
P49810P35790PSEN2CHKA0.18321163940
P49810P49810PSEN2PSEN20.23615474363
P63261P49810ACTG1PSEN20.18321163940
Q02410P49810APBA1PSEN20.2112196555
Q13325P49810IFIT5PSEN20.18321163940
Q13685P49810AAMPPSEN20.18321163940
Q15717P49810ELAVL1PSEN20.18321163940
Q53EZ4P49810CEP55PSEN20.18321163940
Q8NBT2P49810SPC24PSEN20.18321163940
Q92542P49810NCSTNPSEN20.6112297508,10993067,15474363
Q92902P49810HPS1PSEN20.18321163940
Q92947P49810GCDHPSEN20.18321163940
Q96BI3P49810APH1APSEN20.69212297508,15474363,12471034
Q96CN4P49810EVI5LPSEN20.18321163940
Q99767P49810APBA2PSEN20.2112196555
Q9NZ42P49810PSENENPSEN20.50712198112,15474363,22074918
Q9UMF0P49810ICAM5PSEN20.30911719200
Q9Y2H9P49810MAST1PSEN20.28621163940
Q9Y4K3P49810TRAF6PSEN20.50718996842,23707529
Q9Y6B2P49810EID1PSEN20.33221163940
Q13508P49810ART3PSEN20.12626186194
Q07817P49810BCL2L1PSEN20.7410446169
P53041P49810PPP5CPSEN20.12626496610
PPI - InWeb_IM
Gene AGene BMI 1Interaction 1MI 2Interaction 2
IFIT3PSEN2MI:0045experimental interaction detectionMI:0461interaction database
MGEA5PSEN2MI:0045experimental interaction detectionMI:0461interaction database
FLNBPSEN2MI:0045experimental interaction detectionMI:0461interaction database
ECDPSEN2MI:0045experimental interaction detectionMI:0461interaction database
APBA3PSEN2MI:0045experimental interaction detectionMI:0461interaction database
NGFPSEN2MI:0362inferenceMI:1106pathways database
APPPSEN2MI:0045experimental interaction detectionMI:0461interaction database
JUNPSEN2MI:0045experimental interaction detectionMI:0461interaction database
LIPFPSEN2MI:0045experimental interaction detectionMI:0461interaction database
CAPN1PSEN2MI:0045experimental interaction detectionMI:0461interaction database
NGFRPSEN2MI:0362inferenceMI:1106pathways database
UBCPSEN2MI:0045experimental interaction detectionMI:0461interaction database
GFAPPSEN2MI:0045experimental interaction detectionMI:0461interaction database
ATF2PSEN2MI:0045experimental interaction detectionMI:0461interaction database
FLNAPSEN2MI:0045experimental interaction detectionMI:0461interaction database
DNAJB1PSEN2MI:0045experimental interaction detectionMI:0461interaction database
NOS3PSEN2MI:0045experimental interaction detectionMI:0461interaction database
SRIPSEN2MI:0045experimental interaction detectionMI:0461interaction database
CTNNB1PSEN2MI:0362inferenceMI:0461interaction database
CHKAPSEN2MI:0045experimental interaction detectionMI:0461interaction database
NOTCH1PSEN2MI:0362inferenceMI:0461,MI:1106interaction database,pathways database
CLK1PSEN2MI:0045experimental interaction detectionMI:0461interaction database
PSEN1PSEN2MI:0045experimental interaction detectionMI:0461interaction database
PSEN2PPP5CMI:0045experimental interaction detectionMI:0461interaction database
PSEN2TSPAN5MI:0045experimental interaction detectionMI:0461interaction database
PSEN2RAB11AMI:0362inferenceMI:0461interaction database
PSEN2ACTG1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2DLK1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2APBA1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2NOTCH2MI:0362inferenceMI:0461,MI:1106interaction database,pathways database
PSEN2BCL2L1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2IFIT5MI:0045experimental interaction detectionMI:0461interaction database
PSEN2ITGB3BPMI:0362inferenceMI:1106pathways database
PSEN2ART3MI:0045experimental interaction detectionMI:0461interaction database
PSEN2AAMPMI:0045experimental interaction detectionMI:0461interaction database
PSEN2FHL2MI:0045experimental interaction detectionMI:0461interaction database
PSEN2DYNC1H1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2KIF22MI:0045experimental interaction detectionMI:0461interaction database
PSEN2ERBB4MI:0362inferenceMI:1106pathways database
PSEN2RHEBMI:0045experimental interaction detectionMI:0461interaction database
PSEN2ELAVL1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2PDCD4MI:0045experimental interaction detectionMI:0461interaction database
PSEN2CEP55MI:0045experimental interaction detectionMI:0461interaction database
PSEN2KCNIP4MI:0045experimental interaction detectionMI:0461interaction database
PSEN2SPC24MI:0045experimental interaction detectionMI:0461interaction database
PSEN2EXOC6MI:0045experimental interaction detectionMI:0461interaction database
PSEN2APH1BMI:0045experimental interaction detectionMI:0461,MI:1106interaction database,pathways database
PSEN2NCSTNMI:0045experimental interaction detectionMI:0461,MI:1106interaction database,pathways database
PSEN2RYR2MI:0362inferenceMI:0461interaction database
PSEN2HPS1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2GCDHMI:0045experimental interaction detectionMI:0461interaction database
PSEN2APH1AMI:0045experimental interaction detectionMI:0461,MI:1106interaction database,pathways database
PSEN2EVI5LMI:0045experimental interaction detectionMI:0461interaction database
PSEN2FAF2MI:0045experimental interaction detectionMI:0461interaction database
PSEN2METTL2AMI:0362inferenceMI:0461interaction database
PSEN2NOTCH4MI:0362inferenceMI:0461,MI:1106interaction database,pathways database
PSEN2APBA2MI:0045experimental interaction detectionMI:0461interaction database
PSEN2CIB1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2ECSITMI:0045experimental interaction detectionMI:0461interaction database
PSEN2RNF32MI:0045experimental interaction detectionMI:0461interaction database
PSEN2FBXL12MI:0045experimental interaction detectionMI:0461interaction database
PSEN2PSENENMI:0045experimental interaction detectionMI:0461,MI:1106interaction database,pathways database
PSEN2NOTCH3MI:0362inferenceMI:0461,MI:1106interaction database,pathways database
PSEN2ICAM5MI:0045experimental interaction detectionMI:0461interaction database
PSEN2UBQLN1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2CTNND2MI:0362inferenceMI:0461interaction database
PSEN2ERGIC3MI:0045experimental interaction detectionMI:0461interaction database
PSEN2MAST1MI:0045experimental interaction detectionMI:0461interaction database
PSEN2KCNIP3MI:0045experimental interaction detectionMI:0461interaction database
PSEN2TRAF6MI:0045experimental interaction detectionMI:0461,MI:1106interaction database,pathways database
PSEN2EID1MI:0045experimental interaction detectionMI:0461interaction database