Disease associated variation - GWASdb |
Chr | Pos | SNP ID(dbSNP 142) | Ref | Alt | Ori SNP ID | P-value | Drug Name | Drug Anno | GWAS Trait | HPO ID | DO ID | AA | Type | Trait or Drug |
3 | 36487492 | rs936154 | G | A | rs936154 | 0.0006497 | INFLIXIMAB|ADALIMUMAB|IMMUNOGLOBULIN G | TUMOR NECROSIS FACTOR-ALPHA|ANTIRHEUMATIC AGENTS|ANTIBODIES, MONOCLONAL, HUMANIZED|TNFR-FC FUSION PROTEIN|ANTIBODIES, MONOCLONAL|RECEPTORS, TUMOR NECROSIS FACTOR | Anti-TNF treatment response in rheumatoid arthritis (by DAS-28 score change at 3 months) | HPOID:0001370 | DOID:7148 | G | intron | GWASdb_drug |
3 | 36487492 | rs936154 | G | A | rs936154 | 6.50E-04 | LEUCOVORIN|METHOTREXATE | SLCO1B1 PROTEIN, HUMAN|ORGANIC ANION TRANSPORTERS | Methotrexate clearance (acute lymphoblastic leukemia) | HPOID:0006721 | DOID:9952|DOID:12603 | G | intron | GWASdb_drug |
3 | 36487696 | rs936156 | C | T | rs936156 | 0.000791 | INFLIXIMAB|ADALIMUMAB|IMMUNOGLOBULIN G | TUMOR NECROSIS FACTOR-ALPHA|ANTIRHEUMATIC AGENTS|ANTIBODIES, MONOCLONAL, HUMANIZED|TNFR-FC FUSION PROTEIN|ANTIBODIES, MONOCLONAL|RECEPTORS, TUMOR NECROSIS FACTOR | Anti-TNF treatment response in rheumatoid arthritis (by DAS-28 score change at 3 months) | HPOID:0001370 | DOID:7148 | T | intron | GWASdb_drug |
3 | 36487696 | rs936156 | C | T | rs936156 | 7.91E-04 | LEUCOVORIN|METHOTREXATE | SLCO1B1 PROTEIN, HUMAN|ORGANIC ANION TRANSPORTERS | Methotrexate clearance (acute lymphoblastic leukemia) | HPOID:0006721 | DOID:9952|DOID:12603 | T | intron | GWASdb_drug |
3 | 36428232 | rs9870425 | A | T | rs9870425 | 8.46E-05 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | A | intron | GWASdb_trait |
3 | 36432081 | rs4505641 | C | T | rs4505641 | 2.17E-05 | | | Blood Pressure | HPOID:0011025 | DOID:10763 | T | intron | GWASdb_trait |
3 | 36470307 | rs4678878 | T | C | rs4678878 | 9.30E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | C | intron | GWASdb_trait |
3 | 36470307 | rs4678878 | T | C | rs4678878 | 7.65E-05 | | | Blood Pressure | HPOID:0011025 | DOID:10763 | C | intron | GWASdb_trait |
3 | 36473840 | rs11129714 | T | C | rs11129714 | 5.71E-05 | | | Blood Pressure | HPOID:0011025 | DOID:10763 | T | intron | GWASdb_trait |
3 | 36487492 | rs936154 | G | A | rs936154 | 0.0006497 | | | Anti-TNF treatment response in rheumatoid arthritis (by DAS-28 score change at 3 months) | HPOID:0001370 | DOID:7148 | G | intron | GWASdb_trait |
3 | 36487492 | rs936154 | G | A | rs936154 | 6.50E-04 | | | Methotrexate clearance (acute lymphoblastic leukemia) | HPOID:0006721 | DOID:9952|DOID:12603 | G | intron | GWASdb_trait |
3 | 36487696 | rs936156 | C | T | rs936156 | 0.000791 | | | Anti-TNF treatment response in rheumatoid arthritis (by DAS-28 score change at 3 months) | HPOID:0001370 | DOID:7148 | T | intron | GWASdb_trait |
3 | 36487696 | rs936156 | C | T | rs936156 | 7.91E-04 | | | Methotrexate clearance (acute lymphoblastic leukemia) | HPOID:0006721 | DOID:9952|DOID:12603 | T | intron | GWASdb_trait |
3 | 36504281 | rs6767011 | A | G | rs6767011 | 5.44E-05 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
3 | 36516326 | rs1350146 | G | A | rs1350146 | 4.30E-05 | | | Malaria | HPOID:0004386|HPOID:0002315|HPOID:0001945|HPOID:0002829|HPOID:0002013|HPOID:0002018|HPOID:0001878|HPOID:0000952|HPOID:0003641|HPOID:0000480|HPOID:0001279 | DOID:12365 | G | intron | GWASdb_trait |
3 | 36517935 | rs9881075 | C | A | rs9881075 | 6.39E-05 | | | Graves' disease | HPOID:0100647 | DOID:12361 | A | intron | GWASdb_trait |
3 | 36524206 | rs1456074 | C | T | rs1456074 | 2.10E-04 | | | Amyotrophic Lateral Sclerosis | HPOID:0007354 | DOID:332 | T | intron | GWASdb_trait |
3 | 36524206 | rs1456074 | C | T | rs1456074 | 6.41E-05 | | | Blood Pressure | HPOID:0011025 | DOID:10763 | T | intron | GWASdb_trait |