PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NEDD4L STAC 19953087 biogrid exp GP GP G GP G GP GP G GP G GP P G GP GP GP GP G GP GP G G GP G GP G STAC NCKIPSD 18654987 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G ANKLE2 STAC 26186194 biogrid exp G G G G G GP G G G G G G G G G G GP G G G G G G G G G GP GP G YWHAZ STAC 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC PARP2 21812934 mint,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G G G GP GP G GP GP G G GP G STAC LIMD1 18654987 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KIAA1958 STAC 25416956 biogrid,intact exp GP GP G P GP G P P G GP GP GP GP GP GP GP GP G P GP GP GP GP P GP GP G LRRK2 STAC 24510904 intact exp G G G G G GP G GP G G GP GP GP G G G GP G GP G G G GP G G GP P G APP STAC 21832049 innatedb,biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G LMNA STAC 18654987 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC LZTS2 25416956 biogrid,intact exp GP GP G G G GP G G GP G GP GP G G G GP GP G GP G GP GP GP G GP G GP GP G TRIP6 STAC 18654987 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FBXO25 STAC 23940030 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KANK2 STAC 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP G G GP GP GP GP GP GP G GP G FBXO11 STAC 26186194 biogrid exp G G G G G GP G G G G G GP GP G G GP GP G G G GP G G G GP G G G G YWHAE STAC 16260042 mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC C9orf156 18654987 biogrid,intact exp GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP GP GP G GP G GP GP G EPS8L3 STAC 23023127 pred G G G G GP GP G GP GP G P G GP G G GP GP GP GP G G G GP GP G GP G NPHP1 STAC 23023127 pred P P G P P GP P P P P P G GP G P P P G P P GP STAC2 STAC 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP P GP G GP GP GP GP G STAC EPS8L2 23023127 pred GP GP G GP P GP G GP GP GP G G GP GP G GP G GP GP GP P GP P GP GP G UBC STAC 23023127 pred STAC ITSN2 23023127 pred G G G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G EGFR STAC 25402006 pred GP GP G GP G G GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G STAC VAV3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G NOXO1 STAC 23023127 pred G G G STAC RUSC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBL7 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SRGAP2 STAC 23023127 pred G G G G G G G G G G G G G G G G G G ARHGEF19 STAC 23023127 pred G G G G G G G G G G G ABI1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC DBNL 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G NEDD9 STAC 23023127 pred GP GP G G GP GP G GP GP GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3PXD2B STAC 23023127 pred GP GP G G G GP G G GP G GP G GP G G G GP GP GP G GP GP GP G G G GP GP G NCF1 STAC 23023127 pred P P P P VAV1 STAC 23023127 pred GP GP G GP GP G P P G P GP GP GP G GP GP G GP G GP G GP P P GP GP GP G NCF4 STAC 23023127 pred G G G GP G GP GP G G G G GP G NCF4 STAC 23023127 pred G G G GP G GP GP G G G G GP G HCLS1 STAC 23023127 pred G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G G SUMO1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBFD1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF2 STAC 23023127 pred P P P GP P P P P P P P P P P P GP ELANE STAC 23023127 pred G GP G G NCK1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SUMO4 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP GP GP G GP GP GP G ARHGEF16 STAC 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G IGFBP7 STAC 23023127 pred G G G G G G G G G G GP G G G G G G G GP G G G G G G G G GP G MYO1E STAC 23023127 pred GP P G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G MAP3K11 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC DNMT3B 23023127 pred GP P G G GP GP G GP P GP GP GP P G GP GP GP GP G GP P GP GP GP GP GP GP ARHGEF9 STAC 23023127 pred GP GP G P GP G GP GP G GP GP G G G G GP G GP G GP G GP P G GP G P G HERPUD1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGAP4 STAC 23023127 pred G G G GP G GP GP G G G GP G STAC ASAP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RIMBP3C STAC 23023127 pred P P P P SRGAP3 STAC 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP G G G G G G GP G G G STAC CASS4 23023127 pred P P P P P P P P P P P P P P P GP P P P UBASH3B STAC 23023127 pred P P G G GP GP G P P G P P GP P P GP P GP P P P P GP P P MAPK8IP2 STAC 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G GRAP2 STAC 23023127 pred P P P P P P P P P P P P P P P STAC ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STAC PACSIN3 23023127 pred GP GP GP G GP P P GP P G G GP GP GP GP GP GP GP GP GP GP P G STAC RIMBP3 23023127 pred NEDD4 STAC 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G SRGAP1 STAC 23023127 pred G GP G GP G G GP G GP GP G G G GP GP G GP G G G GP G G GP G SH3D21 STAC 23023127 pred P GP G G GP P G GP GP G GP GP P GP GP GP P GP G GP P GP GP GP P P GP G ABL2 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SASH1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G G GP G GP G GP GP GP GP G G GP GP G STAC SH3GLB1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G FCHSD2 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP P GP GP GP GP G G AHI1 STAC 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP GP GP GP G SQSTM1 STAC 23023127 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G THBS1 STAC 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP G GP P GP GP GP P G STAM STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G CRK STAC 23023127 pred GP G G G G G G GP GP G GP GP G G G GP G G GP G GP GP GP GP GP G GP G G RASA1 STAC 23023127 pred GP G G G GP GP G G G G G G G G G G GP G G G GP G G G G G GP G G PPP1R13L STAC 23023127 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G PLCG1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TFEC STAC 23023127 pred P G G P G P P GP P GP GP P P P P P P P G P P G RAD23B STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YAP1 STAC 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TMUB2 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MYO15B STAC 23023127 pred RIMBP3B STAC 23023127 pred DHX9 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SORBS3 STAC 23023127 pred G G G G G GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP G G SNX18 STAC 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP GP GP G GP G GP GP G SOCS3 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G UBXN2B STAC 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G SLA STAC 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G PSTPIP1 STAC 23023127 pred G G GP G GP G GP GP G G G G GP G G RUSC2 STAC 23023127 pred GP GP G P GP G GP GP G GP GP GP GP G P GP GP P G P P GP GP GP GP GP GP G BCAR1 STAC 23023127 pred GP GP G P GP G GP GP G GP GP GP GP GP GP GP GP G GP GP GP GP GP GP GP GP G MAP3K10 STAC 23023127 pred P P P P P P P P P P P P P P P P P P P P P GRB2 STAC 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC TMUB1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NGEF STAC 23023127 pred P GP G P GP G P GP G GP GP P GP G GP GP G GP P GP P P GP P GP GP G KALRN STAC 23023127 pred P P G P GP G P P G P P P P P GP P P P P P P GP P P STAC NSFL1C 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G STAC STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LYN STAC 23023127 pred GP G G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP GP GP GP G G ARHGEF7 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G BTK STAC 23023127 pred G G GP G G GP GP G G GP G ITSN1 STAC 23023127 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP GP G STAC SH3GL1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TPM2 STAC 25402006 pred G G G G G G G G G G G RAD23A STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ABL1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIK3R1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AKT1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARHGEF6 STAC 23023127 pred G GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G G G G G GP G GP G G STAC SNX9 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAP3K9 STAC 23023127 pred P GP G P GP G GP G GP GP P G G GP GP P GP G GP GP GP GP GP GP GP GP G SP100 STAC 23023127 pred GP GP G GP P G GP GP GP GP GP GP G GP P GP P G GP GP GP GP GP GP GP P G MIA2 STAC 23023127 pred P P P P GP GP P P G GP P P GP P P P G STAC3 STAC 23023127 pred G G G G G G G G G G G G G G PLCG2 STAC 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G FCHSD1 STAC 23023127 pred P P P P P P P P P GP P P P P G P P P P P GP P P RP1 STAC 23023127 pred P P STAC ARHGAP26 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G STAC RAD18 23023127 pred P P P P GP P P G P P GP P SASH3 STAC 23023127 pred GP G G G G GP G G GP G G G GP GP G G GP G GP G GP GP GP G G GP GP GP G TRH STAC 23023127 pred P G P P G STAC SAMSN1 23023127 pred G GP G GP P G P GP P P GP GP GP GP P P P P GP GP GP P CTTN STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RIMBP2 STAC 23023127 pred P P G P GP G P P G GP P P G GP GP GP G P P P GP P P GP P G STAC SH3GL2 23023127 pred G GP G G G GP GP G G UBXN11 STAC 23023127 pred G GP G G G GP G GP P G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TRIP10 STAC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CXCL10 STAC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NOXA1 STAC 23023127 pred GP GP G G G GP G G GP G GP GP G G G GP GP GP GP G GP GP GP G GP G GP GP G VAV2 STAC 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP G STAC SP140L 23023127 pred G G G G G GP G G G G G G G G G G G G G G G GP G CRKL STAC 23023127 pred GP G G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP G G GP GP GP G G FYN STAC 23023127 pred G GP G G GP GP G G GP G GP GP G GP G G GP G G G G G G G G GP G G G OSTF1 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G UBQLNL STAC 23023127 pred P P P P P P P P G P P P P GP PRMT2 STAC 23023127 pred G GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP GP GP G GP GP G STAC BAIAP2L1 23023127 pred P GP P P G P GP GP GP GP P G GP P P GP G GP GP GP P GP P GP GP STAC SORBS1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G STAC MAPK8IP1 23023127 pred P P G P GP G P P G P P P P P GP P G P P P P P P P GP DNMBP STAC 23023127 pred GP GP G G G GP G GP GP G G G GP G G G GP GP G G GP GP G GP G G GP G G TRIO STAC 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G STAC BAIAP2 23023127 pred P P G G GP GP G GP P G GP GP GP GP P GP GP GP G GP GP P P P P GP GP G RBBP7 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PEX13 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G OBSCN STAC 23023127 pred GP P P P GP GP GP P P GP G P P P P G P GP GP GP GP GP GP P SH3PXD2A STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G MLK4 STAC 23023127 pred P GP G G GP GP G GP G GP GP GP GP G GP GP GP G GP G GP GP P GP GP G NCF1B STAC 23023127 pred FYB STAC 23023127 pred G G G GP G G G G G G G GP G G G G G G G G GP G STAC CD2AP 23023127 pred GP GP G GP P G G GP GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP ARHGEF37 STAC 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G P G GP G GP G GP G GP GP G BAIAP2L2 STAC 23023127 pred P P G P P GP GP P P P GP P P P P P P P GP P GP P NEBL STAC 23023127 pred GP GP G G G G G GP GP G GP GP GP GP G GP G G GP G G G G G GP P GP G G STAC HERPUD2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NCF2 STAC 23023127 pred G G GP G G G GP GP G G G G G G G G GP G G CCL2 STAC 23023127 pred GP GP G P GP G G GP GP GP GP GP G GP GP GP GP G GP GP P G GP GP GP P G SH3KBP1 STAC 23023127 pred G G G G GP GP G G G G G G G GP G G GP G G G GP G G G G GP G G G NCK2 STAC 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3RF3 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G STAC MYOF 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G AMPH STAC 23023127 pred G G G G GP G G GP G G G G G GP G GP G G G G G G G G G STAC SH3GL3 23023127 pred G G G G GP G G G G G G G G G GP G GP G G G G G G GP GP G GRB10 STAC 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PRKCQ STAC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SH3RF1 STAC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEB STAC 23023127 pred G P G G G G P G G G G G GP G P G MYO1F STAC 23023127 pred G G G G GP G G G G G G G GP G G G G G G G G GP G GP G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q99469 P05067-7 pull down 21832049 direct interaction X 2 Q99469 enzymatic study 23940030 direct interaction X 2 Q99469 Q9BRK4 two hybrid 25416956 direct interaction X 2 Q99469 B7Z2P9 pull down 19953087 direct interaction X 2 Q99469 P02545-5 two hybrid 18654987 direct interaction X 2 Q99469 Q9BU70 two hybrid 18654987 direct interaction X 2 Q99469 Q63ZY3-3 two hybrid 25416956 direct interaction X 2 Q99469 Q8N8K9 two hybrid 25416956 direct interaction X 2 Q99469 pull down 19953087 direct interaction X 2 Q99469 Q15654 two hybrid 18654987 direct interaction X 2 Q99469 two hybrid 18654987 direct interaction X 2 Q99469 Q9UGP4 two hybrid 18654987 direct interaction X 2 Q9UGN5 Q99469 protein array 21812934 adp ribosylation reaction X 2 Q9UGN5 Q99469 enzymatic study 21812934 adp ribosylation reaction X 2 Q99469 P62258 peptide array 16260042 direct interaction X 2 Q99469 P62258 anti bait coimmunoprecipitation 16260042 physical association X 2 Q99469 Q9BU70 two hybrid 18654987 physical association X 2 Q99469 P02545 two hybrid 18654987 physical association X 2 Q5S007 Q99469 protein array 24510904 direct interaction X 2 Q99469 Q15654 two hybrid 18654987 physical association X 2 Q99469 Q9NZQ3 two hybrid 18654987 physical association X 2 Q99469 Q9UGP4 two hybrid 18654987 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B NEDD4L STAC MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_165772 bait prey STAC C9orf156 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_96859|BIOGRID_184835 bait|bait prey|prey APP STAC MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_227830 prey bait STAC LIMD1 MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_184838|UniProt_96862 bait|bait prey|prey STAC PARP2 MI:0089(protein array)|MI:0089(protein array) 21812934 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0557(adp ribosylation reaction)|MI:0557(adp ribosylation reaction) (intact)|(intact) UniProt_116649|UniProt_116595 neutral component|neutral component neutral component|neutral component FBXO25 STAC MI:0004(affinity chromatography technology) 23940030 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_284550 bait prey TRIP6 STAC MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_96860|BIOGRID_184836 prey|prey bait|bait LMNA STAC MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_184834|UniProt_96792 prey|prey bait|bait YWHAE STAC MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array) 10,16260042 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint) MINT_71702|MINT_71703|UniProt_82824|UniProt_82825|MINT_41768|MINT_41767 prey|bait|prey|bait|bait|prey bait|prey|bait|prey|prey|bait STAC NCKIPSD MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_184837|UniProt_96861 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAZ STAC 26186194 0004 HT FBXO11 STAC 26186194 0004 HT ANKLE2 STAC 26186194 0004 HT YWHAZ STAC 26186194 0004 HT FBXO11 STAC 26186194 0004 HT ANKLE2 STAC 26186194 0004 HT LMNA STAC 18654987 0018 HT YWHAE STAC 16260042,16260042 0006,0081 LC TRIP6 STAC 18654987 0018 HT LRRK2 STAC 24510904 0089 LC KANK2 STAC 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT KIAA1958 STAC 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT FBXO25 STAC 23940030 0415 LC STAC LZTS2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT STAC TRMO 18654987 0018 HT STAC NCKIPSD 18654987 0018 HT STAC PARP2 21812934,21812934 0415,0089 LC STAC LIMD1 18654987 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q99469 Q5S007 STAC LRRK2 0.183 24510904 Q99469 Q8TCJ0 STAC FBXO25 0.183 23940030 Q9NZQ3 Q99469 NCKIPSD STAC 0.49 18654987,unassigned1304 Q99469 Q62940 STAC NEDD4 0.183 19953087 Q99469 P02545 STAC LMNA 0.454 18654987 Q9UGN5 Q99469 PARP2 STAC 0.065 21812934 Q99469 A0A0C4DGS5 STAC A0A0C4DGS5 0.236 unassigned1304 Q99469 P26367 STAC PAX6 0.236 unassigned1304 Q99469 P78424 STAC POU6F2 0.236 unassigned1304 Q99469 Q02548 STAC PAX5 0.236 unassigned1304 Q99469 Q7Z3S9 STAC NOTCH2NL 0.236 unassigned1304 Q9UGP4 Q99469 LIMD1 STAC 0.332 18654987 Q99469 A4D127 STAC MEOX2 {ECO:0000313|EMBL:EAL24289.1} 0.236 unassigned1304 Q9BRK4 Q99469 LZTS2 STAC 0.376 unassigned1304,25416956 Q99469 Q8N8K9 STAC KIAA1958 0.376 unassigned1304,25416956 Q99469 Q63ZY3 STAC KANK2 0.376 unassigned1304,25416956 Q99469 P62258 STAC YWHAE 0.702 16260042 Q99469 Q96PU5 STAC NEDD4L 0.183 19953087 Q9BU70 Q99469 C9ORF156 STAC 0.332 18654987 Q99469 P63104 STAC YWHAZ 0.126 26186194 Q99469 P05067 STAC APP 0.183 21832049 Q99469 Q86XL3 STAC ANKLE2 0.126 26186194 Q99469 Q86XK2 STAC FBXO11 0.126 26186194 Q99469 Q15654 STAC TRIP6 0.454 18654987

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 LMNA STAC MI:0045 experimental interaction detection MI:0461 interaction database APP STAC MI:0045 experimental interaction detection MI:0461 interaction database NEDD4 STAC MI:0362 inference MI:0461 interaction database YWHAE STAC MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ STAC MI:0045 experimental interaction detection MI:0461 interaction database TRIP6 STAC MI:0045 experimental interaction detection MI:0461 interaction database LRRK2 STAC MI:0045 experimental interaction detection MI:0461 interaction database KANK2 STAC MI:0045 experimental interaction detection MI:0461 interaction database FBXO11 STAC MI:0045 experimental interaction detection MI:0461 interaction database ANKLE2 STAC MI:0045 experimental interaction detection MI:0461 interaction database KIAA1958 STAC MI:0045 experimental interaction detection MI:0461 interaction database FBXO25 STAC MI:0045 experimental interaction detection MI:0461 interaction database NEDD4L STAC MI:0045 experimental interaction detection MI:0461 interaction database STAC LZTS2 MI:0045 experimental interaction detection MI:0461 interaction database STAC TRMO MI:0045 experimental interaction detection MI:0461 interaction database STAC NCKIPSD MI:0045 experimental interaction detection MI:0461 interaction database STAC PARP2 MI:0045 experimental interaction detection MI:0461 interaction database STAC LIMD1 MI:0045 experimental interaction detection MI:0461 interaction database