DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome KLHL35 3'UTR 5ee3921a7a BA056987 NM_001039548 chr11:74811086-74818661:- KLHL35 3'UTR cbb78114d6 BA056988 NM_001039548 chr11:74811113-74818661:- KLHL35 3'UTR 4fe25add4d BA056989 NM_001039548 chr11:74811086-74818661:- KLHL35 3'UTR bf0dcad11b BA056990 NM_001039548 chr11:74814086-74818661:- KLHL35 5'UTR 5ee3921a7a CA088447 NM_001039548 chr11:74811273-74818881:- KLHL35 5'UTR cbb78114d6 CA088448 NM_001039548 chr11:74811273-74818755:- KLHL35 5'UTR 4fe25add4d CA088449 NM_001039548 chr11:74815139-74818755:- KLHL35 5'UTR bf0dcad11b CA088450 NM_001039548 chr11:74815139-74818884:- KLHL35 5'UTR 9821a797a3 NM_001039548 chr11:74814087-74815532:-

DNA & RNA Element - miRTarBase Target Gene (Entrez ID) miRTarBase ID miRNA Species (miRNA) Target Gene Species (Target Gene) Experiments Support Type References (PMID) MIRT018223 hsa-miR-335-5p Homo sapiens KLHL35 283212 Homo sapiens Microarray Functional MTI (Weak) 18185580

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004481 hsa-let-7a* 283212 KLHL35 cuuucugucaucuAACAUAUc ||||||| auggucccuuuucUUGUAUAa 2 9 103 123 [hg19:11:75133501-75133521:-] 0.5783 140 7 -3.48 -1.2074 MIMAT0004482 hsa-let-7b* 283212 KLHL35 cccuuccgucauccAACAUAUc ||||||| aauggucccuuuucUUGUAUAa 2 9 102 123 [hg19:11:75133501-75133522:-] 0.5783 140 7 -4.63 -1.2074 MIMAT0004486 hsa-let-7f-1* 283212 KLHL35 cccuuccguuaucuAACAUAUc ||||||| aauggucccuuuucUUGUAUAa 2 9 102 123 [hg19:11:75133501-75133522:-] 0.5783 140 7 -4.55 -1.2074 MIMAT0004487 hsa-let-7f-2* 283212 KLHL35 ccuuucugucaucuGACAUAUc :|||||| aauggucccuuuucUUGUAUAa 2 9 102 123 [hg19:11:75133501-75133522:-] 0.5783 124 6 -4.09 -0.2583 MIMAT0004595 hsa-miR-135a* 283212 KLHL35 gcgGUGCCGAGGUUAGGGA-UAu ||| |||:: ||||| || augCAC-ACUCUGCUCCCUCAUg 2 20 52 73 [hg19:11:75133551-75133572:-] 0.5146 121 0 -18.29 -0.1896 MIMAT0001618 hsa-miR-191* 283212 KLHL35 ccCCUGCUUUAGGUUCG-CGUCg || | : :|:| ||| |||| ugGGUCUGUGUUCCAGCUGCAGu 2 21 136 158 [hg19:11:75133466-75133488:-] 0.4922 120 0 -22.45 -0.2561 MIMAT0004748 hsa-miR-423-5p 283212 KLHL35 uuUCAGAGCGAGAGACG-GGGAGu || : | | |||||| ||||| ucAGAUGCACACUCUGCUCCCUCa 2 22 48 71 [hg19:11:75133553-75133576:-] 0.4985 133 0 -25.39 -0.2729 MIMAT0004779 hsa-miR-509-5p 283212 KLHL35 acuaACGGUGACAGACGUCAu ||:: | | ||||||| ucugUGUUCCAG-CUGCAGUc 2 18 140 159 [hg19:11:75133465-75133484:-] 0.4922 147 7 -14.15 -0.1655 MIMAT0004795 hsa-miR-574-5p 283212 KLHL35 ugugugaGUGUGUGUGUGUGAGu | || |::||||||| ggcggagCUCAGAUGCACACUCu 2 17 40 62 [hg19:11:75133562-75133584:-] 0.4985 156 7 -20.38 -0.1196 MIMAT0004800 hsa-miR-550 283212 KLHL35 cccGAGAAUGAGGGAGU-CCGUGa ||| |:|||||||| ||||| acaCUC-UGCUCCCUCAUGGCACc 2 21 56 78 [hg19:11:75133546-75133568:-] 0.5146 146 0 -33.33 -0.1725 MIMAT0003259 hsa-miR-591 283212 KLHL35 uguuacucuugggUACCAGa |||||| agcccuuaacuuaAUGGUCc 2 8 90 109 [hg19:11:75133515-75133534:-] 0.5465 120 6 -11.82 -0.1054 MIMAT0003286 hsa-miR-617 283212 KLHL35 cgGUGGAAGUUUACCCUU-CAGa ::||| |:|| |||| ||| ccUGCCUGGAGAU-GGAAUGUCu 2 21 163 184 [hg19:11:75133440-75133461:-] 0.5639 122 0 -20.24 -0.3136 MIMAT0003318 hsa-miR-648 283212 KLHL35 ugGUCACGGG---ACGUGUGAa |:| ||:| |||||||| ggCGGAGCUCAGAUGCACACUc 2 18 40 61 [hg19:11:75133563-75133584:-] 0.4985 152 7 -20.19 -0.2711 MIMAT0005797 hsa-miR-1301 283212 KLHL35 cuucagugaggguccGUCGACGUu |||||||| guugggucuguguucCAGCUGCAg 2 10 134 157 [hg19:11:75133467-75133490:-] 0.4922 145 7 -19.72 -0.1222 MIMAT0010364 hsa-miR-761 283212 KLHL35 acACAGUCAAAGUGGGAC-GACg || |||| | :||||| ||| gcUG-CAGUCU-GCCCUGCCUGg 2 21 151 171 [hg19:11:75133453-75133473:-] 0.5639 124 0 -18.97 -0.1668 MIMAT0010497 hsa-miR-759 283212 KLHL35 caguuuuaacaaacGUGAGACg ||||||| ggagcucagaugcaCACUCUGc 2 9 43 64 [hg19:11:75133560-75133581:-] 0.4985 140 7 -15.83 -0.1261 MIMAT0004975 hsa-miR-509-3-5p 283212 KLHL35 guacuaACGGUGCAGACGUCAu ||:: | ||||||| ggucugUGUUCCAGCUGCAGUc 2 17 138 159 [hg19:11:75133465-75133486:-] 0.4922 148 7 -16.17 -0.1781 MIMAT0004983 hsa-miR-940 283212 KLHL35 ccccucgccccCGGGACGGAa ||||||||| agcugcagucuGCCCUGCCUg 2 11 150 170 [hg19:11:75133454-75133474:-] 0.5639 150 7 -20.13 -0.1416 MIMAT0005829 hsa-miR-1184 283212 KLHL35 ccuucgguaguucagCGACGUCc ||||||| ugggucuguguuccaGCUGCAGu 2 9 136 158 [hg19:11:75133466-75133488:-] 0.4922 140 7 -14.79 -0.3781 MIMAT0005871 hsa-miR-1207-5p 283212 KLHL35 ggggaggGUCGGA-GGGACGGu |||:|| ||||||| ccagcugCAGUCUGCCCUGCCu 2 15 148 169 [hg19:11:75133455-75133476:-] 0.5639 157 7 -29.43 -0.2146 MIMAT0005872 hsa-miR-1207-3p 283212 KLHL35 cuuuACUCCCGGUCGACu || | ||||||| ggucUGUGUUCCAGCUGc 2 15 138 155 [hg19:11:75133469-75133486:-] 0.4922 146 7 -13.94 -0.3662 MIMAT0005939 hsa-miR-1281 283212 KLHL35 cccuCUC-CUCCUCCGCu ||| |||||||| gccuGAGCCAGGAGGCGg 2 14 15 32 [hg19:11:75133592-75133609:-] 0.5591 148 7 -20.92 -0.6361 MIMAT0005941 hsa-miR-1284 283212 KLHL35 cuuuucggucccaGACAUAUcu :|||||| auggucccuuuucUUGUAUAaa 3 10 103 124 [hg19:11:75133500-75133521:-] 0.5783 121 0 -6.53 -0.2524 MIMAT0015014 hsa-miR-3144-5p 283212 KLHL35 gauauAUAGAGAAACCAGGGGa || ||: |||||||: gcccuUAACUUAAUGGUCCCUu 2 18 91 112 [hg19:11:75133512-75133533:-] 0.5465 141 0 -18.13 -0.1265 MIMAT0016856 hsa-miR-4303 283212 KLHL35 gacaggagUCGAGUCUu |||||||| gcaggcggAGCUCAGAu 2 10 37 53 [hg19:11:75133571-75133587:-] 0.4985 145 7 -14.19 -0.1087 MIMAT0000080 hsa-miR-24 283212 KLHL35 gacaaggacgacuuGACUCGGu ||||||| cagauuuggacagcCUGAGCCa 2 9 3 24 [hg19:11:75133600-75133621:-] 0.5591 140 7 -16.39 -0.5508 MIMAT0000271 hsa-miR-214 283212 KLHL35 ugACGGACAGACACGGAC-GACa || | ||||| |||| ||| gcUG-CAGUCUG-CCCUGCCUGg 2 21 151 171 [hg19:11:75133453-75133473:-] 0.5639 120 0 -24.28 -0.1668 MIMAT0000450 hsa-miR-149 283212 KLHL35 cccucACUUCUGUGCCUCGGUCu ||:| | | ||||||| agauuUGGACAGCCUGAGCCAGg 2 19 4 26 [hg19:11:75133598-75133620:-] 0.5591 154 7 -19.12 -0.2212 MIMAT0000736 hsa-miR-381 283212 KLHL35 ugUCUCUCGAACGGGAACAUAu | :| | | ::||||||| uaAUGGUCCCUUUUCUUGUAUa 2 21 101 122 [hg19:11:75133502-75133523:-] 0.5783 148 7 -12.35 -1.2939 MIMAT0004692 hsa-miR-340 283212 KLHL35 uuaGUCAGAGUAACGAA-AUAUu ::||| | || ||| |||| uaaUGGUCCCUUUUCUUGUAUAa 2 20 101 123 [hg19:11:75133501-75133523:-] 0.5783 127 0 -6.38 -1.2538 MIMAT0004903 hsa-miR-300 283212 KLHL35 ucucucucaGACGGGAACAUAu || ::||||||| uaaugguccCUUUUCUUGUAUa 2 14 101 122 [hg19:11:75133502-75133523:-] 0.5783 149 7 -13.60 -1.2932

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G056593 KLHL35 Homo sapiens 283212

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region KLHL35 High_conserved miR-503 chr11:75140859 7-mer-m8 42 CDS, ncRNA KLHL35 High_conserved miR-503 chr11:75141066 7-mer-m8 38 CDS, 5pUTR, ncRNA KLHL35 High_conserved miR-132/212/212-3p chr11:75134086 7-mer-A1 24 ncRNA KLHL35 High_conserved miR-132/212/212-3p chr11:75135258 7-mer-m8 9 ncRNA KLHL35 High_conserved miR-132/212/212-3p chr11:75135526 7-mer-A1 13 ncRNA KLHL35 High_conserved miR-7/7ab chr11:75135696 7-mer-A1 9 ncRNA KLHL35 High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr11:75137260 7-mer-m8 11 ncRNA KLHL35 High_conserved miR-138/138ab chr11:75133665 7-mer-m8 42 CDS, ncRNA KLHL35 High_conserved miR-138/138ab chr11:75134874 8-mer 40 CDS, ncRNA KLHL35 High_conserved miR-138/138ab chr11:75137810 7-mer-m8 20 ncRNA KLHL35 High_conserved miR-139-5p chr11:75135485 7-mer-A1 13 ncRNA KLHL35 High_conserved miR-140/140-5p/876-3p/1244 chr11:75137055 7-mer-A1 4 ncRNA KLHL35 High_conserved miR-142-3p chr11:75137053 7-mer-A1 4 ncRNA KLHL35 High_conserved miR-144 chr11:75137388 7-mer-A1 29 ncRNA KLHL35 High_conserved miR-148ab-3p/152 chr11:75135622 7-mer-A1 20 ncRNA KLHL35 High_conserved miR-150/5127 chr11:75137254 7-mer-m8 9 ncRNA KLHL35 High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr11:75134936 7-mer-m8 2 ncRNA KLHL35 High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr11:75140856 7-mer-m8 53 CDS, ncRNA KLHL35 High_conserved miR-17/17-5p/20ab/20b-5p/93/106ab/427/518a-3p/519d chr11:75134059 8-mer 7 ncRNA KLHL35 High_conserved miR-17/17-5p/20ab/20b-5p/93/106ab/427/518a-3p/519d chr11:75137259 7-mer-m8 9 ncRNA KLHL35 High_conserved miR-193/193b/193a-3p chr11:75141414 7-mer-A1 2 CDS KLHL35 High_conserved miR-199ab-5p chr11:75135036 7-mer-m8 9 ncRNA KLHL35 High_conserved miR-199ab-5p chr11:75137837 7-mer-m8 7 ncRNA KLHL35 High_conserved miR-1ab/206/613 chr11:75134132 8-mer 11 ncRNA KLHL35 High_conserved miR-1ab/206/613 chr11:75137861 7-mer-m8 9 ncRNA KLHL35 High_conserved miR-203 chr11:75134586 7-mer-m8 27 ncRNA KLHL35 High_conserved miR-203 chr11:75135899 8-mer 36 ncRNA KLHL35 High_conserved miR-204/204b/211 chr11:75134080 7-mer-A1 20 ncRNA KLHL35 High_conserved miR-204/204b/211 chr11:75135145 7-mer-m8 20 ncRNA KLHL35 High_conserved miR-21/590-5p chr11:75136982 7-mer-A1 29 ncRNA KLHL35 High_conserved miR-214/761/3619-5p chr11:75137791 7-mer-m8 18 ncRNA KLHL35 High_conserved miR-214/761/3619-5p chr11:75140957 7-mer-m8 47 CDS, ncRNA KLHL35 High_conserved miR-216a chr11:75134160 7-mer-A1 13 ncRNA KLHL35 High_conserved miR-216a chr11:75134183 7-mer-m8 7 ncRNA KLHL35 High_conserved miR-216a chr11:75134203 7-mer-m8 20 ncRNA KLHL35 High_conserved miR-216b/216b-5p chr11:75134160 7-mer-A1 13 ncRNA KLHL35 High_conserved miR-218/218a chr11:75137841 7-mer-m8 31 ncRNA KLHL35 High_conserved miR-22/22-3p chr11:75134753 7-mer-m8 49 CDS, ncRNA KLHL35 High_conserved miR-22/22-3p chr11:75135400 7-mer-A1 7 ncRNA KLHL35 High_conserved miR-22/22-3p chr11:75135542 8-mer 22 ncRNA KLHL35 High_conserved miR-22/22-3p chr11:75136624 7-mer-m8 33 CDS KLHL35 High_conserved miR-122/122a/1352 chr11:75137048 8-mer 9 ncRNA KLHL35 High_conserved miR-24/24ab/24-3p chr11:75133600 8-mer 36 3pUTR, ncRNA KLHL35 High_conserved miR-27abc/27a-3p chr11:75134071 7-mer-A1 18 ncRNA KLHL35 High_conserved miR-101/101ab chr11:75137388 7-mer-A1 29 ncRNA KLHL35 High_conserved miR-29abcd chr11:75141354 7-mer-m8 36 CDS KLHL35 High_conserved miR-29abcd chr11:75141540 7-mer-m8 33 CDS KLHL35 High_conserved miR-31 chr11:75134930 7-mer-m8 11 ncRNA KLHL35 High_conserved miR-103a/107/107ab chr11:75140887 7-mer-A1 47 CDS, ncRNA KLHL35 High_conserved miR-103a/107/107ab chr11:75141589 7-mer-A1 11 CDS KLHL35 High_conserved miR-338/338-3p chr11:75135057 7-mer-m8 13 ncRNA KLHL35 High_conserved miR-338/338-3p chr11:75137504 7-mer-A1 7 ncRNA KLHL35 High_conserved miR-338/338-3p chr11:75140956 7-mer-A1 49 CDS, ncRNA KLHL35 High_conserved miR-33a-3p/365/365-3p chr11:75134972 7-mer-m8 11 ncRNA KLHL35 High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr11:75139554 7-mer-m8 42 CDS, ncRNA KLHL35 High_conserved miR-125a-5p/125b-5p/351/670/4319 chr11:75136812 8-mer 20 ncRNA KLHL35 High_conserved miR-128/128ab chr11:75133791 7-mer-m8 13 CDS, ncRNA KLHL35 High_conserved miR-129-5p/129ab-5p chr11:75137013 7-mer-A1 9 ncRNA KLHL35 High_conserved miR-129-5p/129ab-5p chr11:75137168 7-mer-A1 11 ncRNA KLHL35 High_conserved miR-129-5p/129ab-5p chr11:75137448 7-mer-A1 9 ncRNA KLHL35 High_conserved miR-490-3p chr11:75136853 7-mer-A1 4 ncRNA KLHL35 High_conserved miR-499-5p chr11:75137817 7-mer-m8 18 ncRNA KLHL35 Medium_conserved miR-504/4725-5p chr11:75133976 7-mer-A1 31 ncRNA KLHL35 Medium_conserved miR-505/505-3p chr11:75135413 7-mer-A1 24 ncRNA KLHL35 Medium_conserved miR-590-3p chr11:75137165 7-mer-A1 11 ncRNA KLHL35 Medium_conserved miR-592/599 chr11:75137528 7-mer-m8 4 ncRNA KLHL35 Medium_conserved miR-615-3p chr11:75136760 7-mer-m8 4 ncRNA KLHL35 Medium_conserved miR-873 chr11:75135254 7-mer-m8 11 ncRNA KLHL35 Medium_conserved miR-149 chr11:75133598 7-mer-m8 31 3pUTR, ncRNA KLHL35 Medium_conserved miR-149 chr11:75139571 7-mer-m8 20 CDS, ncRNA KLHL35 Medium_conserved miR-185/882/3473/4306/4644 chr11:75134441 7-mer-m8 20 ncRNA KLHL35 Medium_conserved miR-185/882/3473/4306/4644 chr11:75137687 7-mer-m8 31 ncRNA KLHL35 Medium_conserved miR-224 chr11:75134004 7-mer-m8 24 ncRNA KLHL35 Medium_conserved miR-296-3p chr11:75135351 7-mer-A1 13 ncRNA KLHL35 Medium_conserved miR-300/381/539-3p chr11:75133502 8-mer 7 3pUTR, ncRNA KLHL35 Medium_conserved miR-326/330/330-5p chr11:75134018 7-mer-A1 29 ncRNA KLHL35 Medium_conserved miR-326/330/330-5p chr11:75134272 7-mer-A1 16 ncRNA KLHL35 Medium_conserved miR-326/330/330-5p chr11:75139577 7-mer-A1 38 CDS, ncRNA KLHL35 Medium_conserved miR-335/335-5p chr11:75134932 7-mer-m8 2 ncRNA KLHL35 Medium_conserved miR-339b/339-5p/3586-5p chr11:75136723 8-mer 9 ncRNA KLHL35 Medium_conserved miR-340-5p chr11:75134108 7-mer-m8 9 ncRNA KLHL35 Medium_conserved miR-346 chr11:75135342 7-mer-A1 9 ncRNA KLHL35 Medium_conserved miR-370 chr11:75135179 7-mer-A1 16 ncRNA KLHL35 Medium_conserved miR-374ab chr11:75134634 7-mer-m8 11 ncRNA KLHL35 Medium_conserved miR-376abd/376b-3p chr11:75135306 7-mer-m8 11 ncRNA KLHL35 Medium_conserved miR-376c/741-5p chr11:75134121 8-mer 22 ncRNA KLHL35 Medium_conserved miR-376c/741-5p chr11:75134820 7-mer-m8 51 CDS, ncRNA KLHL35 Medium_conserved miR-377 chr11:75133786 7-mer-m8 60 CDS, ncRNA KLHL35 Medium_conserved miR-378/422a/378bcdefhi chr11:75133923 8-mer 9 ncRNA KLHL35 Medium_conserved miR-378/422a/378bcdefhi chr11:75134020 7-mer-A1 13 ncRNA KLHL35 Medium_conserved miR-378/422a/378bcdefhi chr11:75135139 8-mer 36 ncRNA KLHL35 Medium_conserved miR-378/422a/378bcdefhi chr11:75137824 7-mer-A1 7 ncRNA KLHL35 Medium_conserved miR-384/384-3p chr11:75135395 7-mer-m8 9 ncRNA KLHL35 Medium_conserved miR-411 chr11:75135857 7-mer-m8 29 ncRNA KLHL35 Medium_conserved miR-411 chr11:75137181 7-mer-A1 7 ncRNA KLHL35 Medium_conserved miR-431 chr11:75135468 8-mer 27 ncRNA KLHL35 Medium_conserved miR-433 chr11:75134407 7-mer-m8 4 ncRNA KLHL35 Medium_conserved miR-495/1192 chr11:75135615 7-mer-A1 13 ncRNA

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score KLHL35 RAID00173746 hsa-miR-381-3p miRNA MIMAT0000736 KLHL35 mRNA 283212 Prediction 0.2202 KLHL35 RAID00480742 hsa-miR-3619-3p miRNA MIMAT0019219 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID00761669 hsa-miR-214-3p miRNA MIMAT0000271 KLHL35 mRNA 283212 CLIP-seq//Prediction 0.6308 KLHL35 RAID00781804 hsa-miR-340-5p miRNA MIMAT0004692 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID01044406 hsa-miR-6132 miRNA MIMAT0024616 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID01089115 hsa-miR-24-3p miRNA MIMAT0000080 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID01207318 hsa-miR-508-3p miRNA MIMAT0002880 KLHL35 mRNA 283212 CLIP-seq 0.5483 KLHL35 RAID01209658 hsa-miR-6836-5p miRNA MIMAT0027574 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID01496074 hsa-miR-4659b-5p miRNA MIMAT0019733 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID01946216 hsa-miR-4659a-5p miRNA MIMAT0019726 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID02306108 hsa-miR-7843-5p miRNA MIMAT0030411 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID02502037 hsa-miR-6821-5p miRNA MIMAT0027542 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID02541477 hsa-miR-149-5p miRNA MIMAT0000450 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID02893925 hsa-miR-300 miRNA MIMAT0004903 KLHL35 mRNA 283212 Prediction 0.2202 KLHL35 RAID02999480 hsa-miR-4419a miRNA MIMAT0018931 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID03499058 hsa-miR-1281 miRNA MIMAT0005939 KLHL35 mRNA 283212 Prediction 0.1828 KLHL35 RAID03643295 hsa-miR-335-5p miRNA MIMAT0000765 KLHL35 mRNA 283212 Microarray 0.5483