Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 7085569 rs3772022 C T rs3772022 3.66E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A,G intron GWASdb_drug 2 7097523 rs771315 T C rs771315 4.76E-05 NICOTINE|BUPROPION NICOTINIC AGONISTS|ANTIDEPRESSIVE AGENTS, SECOND-GENERATION Smoking cessation HPOID:0000707 DOID:0050742 T intron GWASdb_drug 2 7097845 rs3772017 C G rs3772017 1.20E-04 NICOTINE|BUPROPION NICOTINIC AGONISTS|ANTIDEPRESSIVE AGENTS, SECOND-GENERATION Smoking cessation HPOID:0000707 DOID:0050742 G intron GWASdb_drug 2 7147973 rs6741819 C T rs6741819 2.00E-07 CHOLESTEROL TRANSCRIPTION FACTORS|MEIS2 PROTEIN, HUMAN|HOMEODOMAIN PROTEINS|ANTIPSYCHOTIC AGENTS Response to antipsychotic treatment HPOID:0000709 DOID:5419 C intron GWASdb_drug 2 7060629 rs771274 C T rs771274 2.22E-04 Graves' disease HPOID:0100647 DOID:12361 A intron GWASdb_trait 2 7062123 rs10495547 G A rs10495547 4.12E-05 Schizophrenia HPOID:0100753 DOID:5419 G intron GWASdb_trait 2 7068927 rs720388 T C rs720388 1.80E-04 Aortic root size HPOID:0002597 DOID:1287 G intron GWASdb_trait 2 7080792 rs1797557 C T rs1797557 4.65E-04 Aortic root size HPOID:0002597 DOID:1287 T intron GWASdb_trait 2 7085569 rs3772022 C T rs3772022 3.66E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A,G intron GWASdb_trait 2 7096989 rs3772019 A G rs3772019 8.60E-06 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 2 7097523 rs771315 T C rs771315 4.76E-05 Smoking cessation HPOID:0000707 DOID:0050742 T intron GWASdb_trait 2 7097845 rs3772017 C G rs3772017 1.20E-04 Smoking cessation HPOID:0000707 DOID:0050742 G intron GWASdb_trait 2 7097845 rs3772017 C G rs3772017 2.20E-05 Urinary metabolites HPOID:0000079 DOID:557 G intron GWASdb_trait 2 7098007 rs3772016 C G rs3772016 2.50E-05 Urinary metabolites HPOID:0000079 DOID:557 G intron GWASdb_trait 2 7101720 rs771318 A G rs771318 4.92E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 2 7101811 rs771319 C T rs771319 4.94E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 2 7104166 rs771320 A C rs771320 2.22E-04 Smoking quantity HPOID:0000707 DOID:0050742 A intron GWASdb_trait 2 7111899 rs3772002 G T rs3772002 5.76E-04 Smoking quantity HPOID:0000707 DOID:0050742 C intron GWASdb_trait 2 7111899 rs3836204 G GT rs3772002 5.76E-04 Smoking quantity HPOID:0000707 DOID:0050742 C intron GWASdb_trait 2 7111899 rs543410060 G GT rs3772002 5.76E-04 Smoking quantity HPOID:0000707 DOID:0050742 C intron GWASdb_trait 2 7119618 rs3771997 G A rs3771997 7.84E-04 Smoking quantity HPOID:0000707 DOID:0050742 C intron GWASdb_trait 2 7142180 rs11685858 G C rs11685858 6.89E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 2 7147973 rs6741819 C T rs6741819 9.50E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 2 7147973 rs6741819 C T rs6741819 2.00E-07 Response to antipsychotic treatment HPOID:0000709 DOID:5419 C intron GWASdb_trait 2 7149509 rs2460405 A G rs2460405 1.37E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 2 7150330 rs447721 C T rs447721 3.49E-04 Lung function (forced expiratory volume in 1 second) HPOID:0002088 DOID:850 A intron GWASdb_trait 2 7150330 rs447721 C T rs447721 1.35E-04 Body mass index HPOID:0001507 DOID:9970 A intron GWASdb_trait 2 7150527 rs445411 T C rs445411 2.05E-04 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 2 7150654 rs381214 C T rs381214 1.35E-04 Body mass index HPOID:0001507 DOID:9970 A intron GWASdb_trait 2 7150758 rs388773 G A,C,T rs388773 3.34E-04 Body mass index HPOID:0001507 DOID:9970 C intron GWASdb_trait 2 7151074 rs412098 A G rs412098 4.98E-04 Amyotrophic lateral sclerosis (sporadic) HPOID:0007354 DOID:332 C intron GWASdb_trait 2 7161586 rs420013 C A rs420013 1.21E-04 Stroke HPOID:0001297 DOID:6713 T intron GWASdb_trait 2 7171364 rs16865853 C T rs16865853 7.19E-05 Blood pressure (response to angiotensin II receptor blocker) HPOID:0011025 DOID:10763 C intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs771296 2 7071535 7071535 intronic 0.973439 0.0116912581074119 GWAS of prostate cancer rs720388 2 7068927 7068927 intronic 0.959582 0.017917907196488 GWAS of prostate cancer rs1375337 2 7060539 7060539 intronic 0.957261 0.0189696344220581 GWAS of prostate cancer rs771253 2 7114174 7114174 intronic 0.924547 0.0340710062767762 GWAS of prostate cancer rs771256 2 7115065 7115065 intronic 0.786394 0.10435980872733501 GWAS of prostate cancer rs4669122 2 7108212 7108212 intronic 0.775957 0.110162344695606 GWAS of prostate cancer rs11679160 2 7080646 7080646 intronic 0.762337 0.117853001250731 GWAS of prostate cancer rs12692328 2 7074937 7074937 intronic 0.748982 0.12552861940949 GWAS of prostate cancer rs771261 2 7125756 7125756 intronic 0.722215 0.141333495763003 GWAS of prostate cancer rs309311 2 7156947 7156947 intronic 0.692511 0.159573323777796 GWAS of prostate cancer rs454999 2 7162879 7162879 intronic 0.647079 0.18904269433960602