PTM - CPLM Gene Name UniProt ID Type Position Code ANAPC1; TSG24 Q9H1A4 Ubiquitination 310 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 184 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 985 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1162 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 905 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 379 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1709 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1700 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 29 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 565 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 477 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 107 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1648 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 695 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 429 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 71 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1693 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 275 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 1066 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 69 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 140 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 694 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 463 K ANAPC1; TSG24 Q9H1A4 Ubiquitination 284 K

PTM - dbPAF Gene Name UniProt ID Position Type Species ANAPC1; TSG24 Q9H1A4 1058 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 118 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1347 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1349 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1552 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1610 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1638 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1698 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 1707 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 202 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 233 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 286 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 291 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 297 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 298 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 299 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 300 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 307 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 313 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 316 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 317 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 331 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 332 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 333 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 334 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 336 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 339 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 341 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 343 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 345 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 351 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 355 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 362 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 364 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 372 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 373 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 377 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 386 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 389 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 46 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 50 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 51 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 518 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 520 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 522 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 524 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 529 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 530 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 536 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 537 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 542 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 547 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 555 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 563 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 564 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 569 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 571 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 596 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 60 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 600 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 65 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 686 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 688 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 699 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 701 T Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 703 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 727 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 731 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 876 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 886 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 892 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 893 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 895 Y Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 916 S Homo sapiens(Human) ANAPC1; TSG24 Q9H1A4 984 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type ANAPC1; TSG24 rs12466309 ACT->GCT T->A 537 T TPLDGVSTPKPLSKL 537 Phosphorylation: CDK1 TypeI- ANAPC1; TSG24 rs12466313 CGG->CAG R->Q 520 T GLPAPSLTMSNTMPR 520 Phosphorylation: PLK1 TypeIII- ANAPC1; TSG24 rs12466313 CGG->CAG R->Q 530 T NTMPRPSTPLDGVST 530 Phosphorylation: CDK1; PLK1 TypeIII- ANAPC1; TSG24 rs13011359 CAG->CGG Q->R 286 S ENVVLKFSEQGGTPQ 286 Phosphorylation TypeIII- ANAPC1; TSG24 rs13011359 CAG->CGG Q->R 291 T KFSEQGGTPQNVATS 291 Phosphorylation: CDK1; PLK1 TypeIII- ANAPC1; TSG24 rs13029913 CAG->CAT Q->H 291 T KFSEQGGTPQNVATS 291 Phosphorylation: CDK1; PLK1 TypeIII- ANAPC1; TSG24 rs13412634 TCT->GCT S->A 355 S AALSRAHSPALGVHS 355 Phosphorylation: CDK1; PLK1 TypeIII- ANAPC1; TSG24 rs62138235 CCA->TCA P->S 530 T NTMPRPSTPLDGVST 530 Phosphorylation: CDK1; PLK1 TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9H1A4 R352-m1 Methylation sNMAALsrAHsPALG Q9H1A4 R1617-m1 Methylation yVLAAEPrLLVPVDV Q9H1A4 S46-p Phosphorylation LRQLQPAsELWssDG Q9H1A4 S50-p Phosphorylation QPAsELWssDGAAGL Q9H1A4 S51-p Phosphorylation PAsELWssDGAAGLV Q9H1A4 S60-p Phosphorylation GAAGLVGsLQEVtIH Q9H1A4 T65-p Phosphorylation VGsLQEVtIHEkQKE Q9H1A4 T118-p Phosphorylation LAVYKAFtVDSPVQQ Q9H1A4 S202-p Phosphorylation SHEVPPGsPREPLPT Q9H1A4 S233-p Phosphorylation KSGSLFGsSRVQYVV Q9H1A4 S286-p Phosphorylation ENVVLKFsEQGGtPQ Q9H1A4 T291-p Phosphorylation KFsEQGGtPQNVATS Q9H1A4 S299-p Phosphorylation PQNVATSssLTAHLR Q9H1A4 S300-p Phosphorylation QNVATSssLTAHLRs Q9H1A4 S307-p Phosphorylation sLTAHLRsLskGDsP Q9H1A4 S309-p Phosphorylation TAHLRsLskGDsPVt Q9H1A4 S313-p Phosphorylation RsLskGDsPVtsPFQ Q9H1A4 T316-p Phosphorylation skGDsPVtsPFQNYS Q9H1A4 S317-p Phosphorylation kGDsPVtsPFQNYSs Q9H1A4 S324-p Phosphorylation sPFQNYSsIHSQSRS Q9H1A4 T332-p Phosphorylation IHSQSRStssPsLHs Q9H1A4 S333-p Phosphorylation HSQSRStssPsLHsR Q9H1A4 S334-p Phosphorylation SQSRStssPsLHsRs Q9H1A4 S336-p Phosphorylation SRStssPsLHsRsPs Q9H1A4 S339-p Phosphorylation tssPsLHsRsPsIsN Q9H1A4 S341-p Phosphorylation sPsLHsRsPsIsNMA Q9H1A4 S343-p Phosphorylation sLHsRsPsIsNMAAL Q9H1A4 S345-p Phosphorylation HsRsPsIsNMAALsr Q9H1A4 S351-p Phosphorylation IsNMAALsrAHsPAL Q9H1A4 S355-p Phosphorylation AALsrAHsPALGVHs Q9H1A4 S362-p Phosphorylation sPALGVHsFsGVQRF Q9H1A4 S364-p Phosphorylation ALGVHsFsGVQRFNI Q9H1A4 S372-p Phosphorylation GVQRFNIssHNQsPK Q9H1A4 S373-p Phosphorylation VQRFNIssHNQsPKR Q9H1A4 S377-p Phosphorylation NIssHNQsPKRHSIS Q9H1A4 S386-p Phosphorylation KRHSISHsPNSNSNG Q9H1A4 S518-p Phosphorylation IPGLPAPsLtMsNtM Q9H1A4 T520-p Phosphorylation GLPAPsLtMsNtMPR Q9H1A4 S522-p Phosphorylation PAPsLtMsNtMPRPs Q9H1A4 T524-p Phosphorylation PsLtMsNtMPRPstP Q9H1A4 S529-p Phosphorylation sNtMPRPstPLDGVs Q9H1A4 T530-p Phosphorylation NtMPRPstPLDGVst Q9H1A4 S536-p Phosphorylation stPLDGVstPKPLsK Q9H1A4 T537-p Phosphorylation tPLDGVstPKPLsKL Q9H1A4 S542-p Phosphorylation VstPKPLsKLLGsLD Q9H1A4 S547-p Phosphorylation PLsKLLGsLDEVVLL Q9H1A4 S555-p Phosphorylation LDEVVLLsPVPELRD Q9H1A4 S563-p Phosphorylation PVPELRDssKLHDsL Q9H1A4 S564-p Phosphorylation VPELRDssKLHDsLy Q9H1A4 S569-p Phosphorylation DssKLHDsLyNEDCT Q9H1A4 Y571-p Phosphorylation sKLHDsLyNEDCTFQ Q9H1A4 T596-p Phosphorylation DPVHNRVtLELsNGS Q9H1A4 S600-p Phosphorylation NRVtLELsNGSMVRI Q9H1A4 S686-p Phosphorylation RNFDFEGsLsPVIAP Q9H1A4 S688-p Phosphorylation FDFEGsLsPVIAPkK Q9H1A4 S699-p Phosphorylation APkKARPsEtGsDDD Q9H1A4 T701-p Phosphorylation kKARPsEtGsDDDWE Q9H1A4 S703-p Phosphorylation ARPsEtGsDDDWEYL Q9H1A4 S727-p Phosphorylation ESHLLNRsLCLsPSE Q9H1A4 S731-p Phosphorylation LNRsLCLsPSEASQM Q9H1A4 S876-p Phosphorylation RSRLVVLsIALYILG Q9H1A4 S886-p Phosphorylation LYILGDEsLVSDEsS Q9H1A4 S892-p Phosphorylation EsLVSDEsSQYLTRI Q9H1A4 S916-p Phosphorylation EQEENRFsFRHSTsV Q9H1A4 S922-p Phosphorylation FsFRHSTsVSSLAER Q9H1A4 S984-p Phosphorylation LIGRQDLskQACEGN Q9H1A4 S1058-p Phosphorylation VVQYPELsDHEFIEE Q9H1A4 S1347-p Phosphorylation MHREKHKsPsYQIKE Q9H1A4 S1349-p Phosphorylation REKHKsPsYQIKEGD Q9H1A4 Y1552-p Phosphorylation KTGGEMNyGFHLAHH Q9H1A4 Y1610-p Phosphorylation LQALRHLyVLAAEPr Q9H1A4 Y1638-p Phosphorylation YALLEVTyKGTQWYE Q9H1A4 Y1698-p Phosphorylation LSKDGVLyVKLRAGQ Q9H1A4 S1707-p Phosphorylation KLRAGQLsYkEDPMG Q9H1A4 K69-ub Ubiquitination QEVtIHEkQKESWQL Q9H1A4 K140-ub Ubiquitination ISQDKSEkAYSSNEV Q9H1A4 K245-ub Ubiquitination YVVDHAMkIVFLNTD Q9H1A4 K275-ub Ubiquitination VWTLRRVkSEEENVV Q9H1A4 K310-ub Ubiquitination AHLRsLskGDsPVts Q9H1A4 K429-ub Ubiquitination EKNSQASkVFITSDL Q9H1A4 K477-ub Ubiquitination SVTNIPAkDAAPVEK Q9H1A4 K694-ub Ubiquitination LsPVIAPkKARPsEt Q9H1A4 K905-ub Ubiquitination RITIAPQkLQVEQEE Q9H1A4 K985-ub Ubiquitination IGRQDLskQACEGNL Q9H1A4 K1066-ub Ubiquitination DHEFIEEkENRLLQL Q9H1A4 K1709-ub Ubiquitination RAGQLsYkEDPMGWQ

PTM - dbPTM UniProt ID Position Code Type Resources References Q9H1A4 51 S Phosphorylation Swiss-Prot 1010711 18669648 Q9H1A4 60 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q9H1A4 65 T Phosphorylation Swiss-Prot 1010711 18669648 Q9H1A4 202 S Phosphorylation Swiss-Prot 1010711 14657031 Q9H1A4 286 S Phosphorylation Swiss-Prot 1010711 14657031 Q9H1A4 291 T Phosphorylation Swiss-Prot 1010711 14657031;18669648 Q9H1A4 341 S Phosphorylation Swiss-Prot 1010711 18669648;18691976;19007248 Q9H1A4 355 S Phosphorylation Swiss-Prot 1010711 14657031;18220336;18669648 Q9H1A4 362 S Phosphorylation Swiss-Prot 1010711 18220336;18669648 Q9H1A4 373 S Phosphorylation Swiss-Prot 1010711 14657031 Q9H1A4 377 S Phosphorylation Swiss-Prot 1010711 14657031;18220336;18691976 Q9H1A4 537 T Phosphorylation Swiss-Prot 1010711 14657031 Q9H1A4 547 S Phosphorylation Swiss-Prot 1010711 18669648;18691976;19690332 Q9H1A4 555 S Phosphorylation Swiss-Prot 1010711 18691976;19690332 Q9H1A4 563 S Phosphorylation Swiss-Prot 1010711 18669648 Q9H1A4 569 S Phosphorylation Swiss-Prot 1010711 18220336 Q9H1A4 571 Y Phosphorylation Swiss-Prot 1010711 14657031 Q9H1A4 686 S Phosphorylation Swiss-Prot 1010711 16565220;18669648;18691976;19369195;19690332 Q9H1A4 688 S Phosphorylation Swiss-Prot 1010711 14657031;15302935;16565220;18669648;18691976;19369195;19690332 Q9H1A4 699 S Phosphorylation Swiss-Prot 1010711 19413330 Q9H1A4 731 S Phosphorylation Swiss-Prot 1010711 15302935 Q9H1A4 51 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 60 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 202 S Phosphorylation PhosphoELM.10011 22067460;14657031 Q9H1A4 286 S Phosphorylation PhosphoELM.10011 22067460;14657031 Q9H1A4 299 S Phosphorylation PhosphoELM.10011 18669648 Q9H1A4 307 S Phosphorylation PhosphoELM.10011 18669648 Q9H1A4 313 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 317 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 333 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 334 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 339 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 341 S Phosphorylation PhosphoELM.10011 18669648 Q9H1A4 343 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 351 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 362 S Phosphorylation PhosphoELM.10011 22067460;18669648;18220336 Q9H1A4 364 S Phosphorylation PhosphoELM.10011 22067460;18669648;14657031 Q9H1A4 373 S Phosphorylation PhosphoELM.10011 14657031;14657031 Q9H1A4 386 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 518 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 522 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 529 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 536 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 547 S Phosphorylation PhosphoELM.10011 22067460;18669648;14657031 Q9H1A4 563 S Phosphorylation PhosphoELM.10011 18669648 Q9H1A4 569 S Phosphorylation PhosphoELM.10011 22067460;18669648;18220336;14657031 Q9H1A4 699 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 703 S Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 731 S Phosphorylation PhosphoELM.10011 22067460;14657031;15302935 Q9H1A4 916 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 1347 S Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 555 S Phosphorylation PhosphoELM.10011 22067460;14657031 Q9H1A4 355 S Phosphorylation PhosphoELM.10011 22067460;18669648;18220336;14657031;14657031;14657031 Q9H1A4 377 S Phosphorylation PhosphoELM.10011 22067460;18220336;14657031;14657031;14657031 Q9H1A4 688 S Phosphorylation PhosphoELM.10011 22067460;18669648;14657031;15302935;14657031;14657031 Q9H1A4 686 S Phosphorylation PhosphoELM.10011 22067460;18669648;14657031 Q9H1A4 65 T Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 316 T Phosphorylation PhosphoELM.10011 22067460 Q9H1A4 524 T Phosphorylation PhosphoELM.10011 22067460;18669648 Q9H1A4 701 T Phosphorylation PhosphoELM.10011 18669648;14657031;14657031 Q9H1A4 537 T Phosphorylation PhosphoELM.10011 22067460;14657031 Q9H1A4 291 T Phosphorylation PhosphoELM.10011 22067460;18669648;14657031;14657031;14657031 Q9H1A4 530 T Phosphorylation PhosphoELM.10011 22067460;18669648;14657031;14657031;14657031 Q9H1A4 520 T Phosphorylation PhosphoELM.10011 18669648;14657031 Q9H1A4 571 Y Phosphorylation PhosphoELM.10011 22067460;14657031 Q9H1A4 1066 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 140 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 1709 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 275 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 310 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9H1A4 429 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 477 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 69 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 694 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 905 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9H1A4 1347 S Phosphorylation Phosphositeplus.1010730 20363803;21406692;22067460 Q9H1A4 1349 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q9H1A4 1707 S Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 202 S Phosphorylation Phosphositeplus.1010730 14657031;18420821;19691289;22067460 Q9H1A4 233 S Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 286 S Phosphorylation Phosphositeplus.1010730 14657031;22067460 Q9H1A4 307 S Phosphorylation Phosphositeplus.1010730 18669648 Q9H1A4 313 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 317 S Phosphorylation Phosphositeplus.1010730 18669648;22067460 Q9H1A4 333 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 334 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 339 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 341 S Phosphorylation Phosphositeplus.1010730 18420821;18669648;18691976;19691289;20068231;22067460 Q9H1A4 343 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 351 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 355 S Phosphorylation Phosphositeplus.1010730 14657031;18220336;18420821;18669648;19276368;19691289;20068231;22067460 Q9H1A4 362 S Phosphorylation Phosphositeplus.1010730 18220336;18420821;18669648;19276368;20068231;22067460 Q9H1A4 364 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 372 S Phosphorylation Phosphositeplus.1010730 16964243;20068231;20363803;21406692;22067460 Q9H1A4 373 S Phosphorylation Phosphositeplus.1010730 14657031;16964243 Q9H1A4 377 S Phosphorylation Phosphositeplus.1010730 14657031;16964243;18220336;18420821;18691976;19276368;19691289;20068231;20363803;21406692;22067460;22115753 Q9H1A4 386 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 46 S Phosphorylation Phosphositeplus.1010730 20363803;22067460 Q9H1A4 50 S Phosphorylation Phosphositeplus.1010730 20068231;22067460 Q9H1A4 51 S Phosphorylation Phosphositeplus.1010730 18669648;20068231;21659604;22067460 Q9H1A4 518 S Phosphorylation Phosphositeplus.1010730 22067460;22115753 Q9H1A4 522 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 529 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 536 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 542 S Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 547 S Phosphorylation Phosphositeplus.1010730 14657031;18669648;18691976;19690332;20068231;20363803;22067460;22115753 Q9H1A4 555 S Phosphorylation Phosphositeplus.1010730 14657031;17001009;18420821;18691976;19690332;20068231;22067460 Q9H1A4 564 S Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 569 S Phosphorylation Phosphositeplus.1010730 14657031;18220336;19276368;22067460 Q9H1A4 60 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;20068231;21659604;22067460 Q9H1A4 600 S Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 686 S Phosphorylation Phosphositeplus.1010730 16565220;18669648;18691976;19690332;20068231;20363803;20562096;21659604;22067460;22115753 Q9H1A4 688 S Phosphorylation Phosphositeplus.1010730 14657031;15302935;16565220;18420821;18669648;18691976;19276368;19369195;19415658;19664994;19664995;19690332;20058876;20068231;20363803;20562096;20815410;21406692;21659604;22067460;22115753 Q9H1A4 699 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 703 S Phosphorylation Phosphositeplus.1010730 18669648;21659604;22067460 Q9H1A4 727 S Phosphorylation Phosphositeplus.1010730 19691289 Q9H1A4 731 S Phosphorylation Phosphositeplus.1010730 14657031;15302935;18420821;19691289;22067460 Q9H1A4 916 S Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 118 T Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 291 T Phosphorylation Phosphositeplus.1010730 14657031;18420821;18669648;20068231;22067460 Q9H1A4 316 T Phosphorylation Phosphositeplus.1010730 22067460 Q9H1A4 520 T Phosphorylation Phosphositeplus.1010730 14657031 Q9H1A4 524 T Phosphorylation Phosphositeplus.1010730 18669648;22067460;22115753 Q9H1A4 530 T Phosphorylation Phosphositeplus.1010730 14657031;18420821;22067460 Q9H1A4 537 T Phosphorylation Phosphositeplus.1010730 14657031;22067460 Q9H1A4 65 T Phosphorylation Phosphositeplus.1010730 18669648;22067460 Q9H1A4 701 T Phosphorylation Phosphositeplus.1010730 14657031 Q9H1A4 1552 Y Phosphorylation Phosphositeplus.1010730 18420821 Q9H1A4 571 Y Phosphorylation Phosphositeplus.1010730 14657031;22067460 Q9H1A4 50 S Phosphorylation HPRD 9.0 20068231 Q9H1A4 51 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 60 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 202 S Phosphorylation HPRD 9.0 19691289 Q9H1A4 286 S Phosphorylation HPRD 9.0 19691289 Q9H1A4 299 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 307 S Phosphorylation HPRD 9.0 18669648 Q9H1A4 313 S Phosphorylation HPRD 9.0 18669648 Q9H1A4 317 S Phosphorylation HPRD 9.0 18669648 Q9H1A4 341 S Phosphorylation HPRD 9.0 18669648,18691976,19691289,19007248,20068231 Q9H1A4 343 S Phosphorylation HPRD 9.0 18212344,19691289 Q9H1A4 355 S Phosphorylation HPRD 9.0 18669648,19651622,19691289,20068231 Q9H1A4 362 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 364 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 372 S Phosphorylation HPRD 9.0 16964243,20068231 Q9H1A4 377 S Phosphorylation HPRD 9.0 17322306,18691976,19651622,19691289,16964243,20068231 Q9H1A4 518 S Phosphorylation HPRD 9.0 20068231 Q9H1A4 529 S Phosphorylation HPRD 9.0 18669648 Q9H1A4 547 S Phosphorylation HPRD 9.0 18669648,18691976,19651622,20068231 Q9H1A4 555 S Phosphorylation HPRD 9.0 18691976,20068231 Q9H1A4 563 S Phosphorylation HPRD 9.0 18669648,19651622,20068231 Q9H1A4 564 S Phosphorylation HPRD 9.0 19651622 Q9H1A4 569 S Phosphorylation HPRD 9.0 18669648 Q9H1A4 686 S Phosphorylation HPRD 9.0 16565220,18669648,18691976,19651622,20068231 Q9H1A4 688 S Phosphorylation HPRD 9.0 16565220,18669648,18691976,19664995,19651622,19664994,18452278,18767875,19415658,20068231 Q9H1A4 699 S Phosphorylation HPRD 9.0 18669648,19413330,18691976 Q9H1A4 703 S Phosphorylation HPRD 9.0 17081983,18669648 Q9H1A4 727 S Phosphorylation HPRD 9.0 19691289 Q9H1A4 731 S Phosphorylation HPRD 9.0 19691289 Q9H1A4 65 T Phosphorylation HPRD 9.0 18669648 Q9H1A4 291 T Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 520 T Phosphorylation HPRD 9.0 18669648,20068231 Q9H1A4 524 T Phosphorylation HPRD 9.0 18669648 Q9H1A4 530 T Phosphorylation HPRD 9.0 18669648 Q9H1A4 701 T Phosphorylation HPRD 9.0 17081983,18669648 Q9H1A4 51 S Phosphorylation SysPTM 1.1 18669648 Q9H1A4 60 S Phosphorylation SysPTM 1.1 18669648 Q9H1A4 341 S Phosphorylation SysPTM 1.1 18691976;18669648 Q9H1A4 343 S Phosphorylation SysPTM 1.1 18212344 Q9H1A4 355 S Phosphorylation SysPTM 1.1 18669648 Q9H1A4 362 S Phosphorylation SysPTM 1.1 18669648 Q9H1A4 372 S Phosphorylation SysPTM 1.1 16964243 Q9H1A4 373 S Phosphorylation SysPTM 1.1 16964243 Q9H1A4 377 S Phosphorylation SysPTM 1.1 17322306;16964243;18691976 Q9H1A4 547 S Phosphorylation SysPTM 1.1 18669648;18691976 Q9H1A4 555 S Phosphorylation SysPTM 1.1 18691976 Q9H1A4 563 S Phosphorylation SysPTM 1.1 18669648 Q9H1A4 686 S Phosphorylation SysPTM 1.1 18669648;18691976;16565220 Q9H1A4 688 S Phosphorylation SysPTM 1.1 17322306;18669648;18691976;16565220 Q9H1A4 703 S Phosphorylation SysPTM 1.1 17081983 Q9H1A4 65 T Phosphorylation SysPTM 1.1 18669648 Q9H1A4 291 T Phosphorylation SysPTM 1.1 18669648 Q9H1A4 701 T Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References ANAPC1 202 S Phosphorylation 19691289 ANAPC1 286 S Phosphorylation 19691289 ANAPC1 291 T Phosphorylation 18669648,20068231 ANAPC1 299 S Phosphorylation 18669648,20068231 ANAPC1 307 S Phosphorylation 18669648 ANAPC1 313 S Phosphorylation 18669648 ANAPC1 317 S Phosphorylation 18669648 ANAPC1 341 S Phosphorylation 18669648,18691976,19691289,19007248,20068231 ANAPC1 343 S Phosphorylation 18212344,19691289 ANAPC1 355 S Phosphorylation 18669648,19651622,19691289,20068231 ANAPC1 362 S Phosphorylation 18669648,20068231 ANAPC1 364 S Phosphorylation 18669648,20068231 ANAPC1 372 S Phosphorylation 16964243,20068231 ANAPC1 377 S Phosphorylation 17322306,18691976,19651622,19691289,16964243,20068231 ANAPC1 50 S Phosphorylation 20068231 ANAPC1 51 S Phosphorylation 18669648,20068231 ANAPC1 518 S Phosphorylation 20068231 ANAPC1 520 T Phosphorylation 18669648,20068231 ANAPC1 524 T Phosphorylation 18669648 ANAPC1 529 S Phosphorylation 18669648 ANAPC1 530 T Phosphorylation 18669648 ANAPC1 547 S Phosphorylation 18669648,18691976,19651622,20068231 ANAPC1 555 S Phosphorylation 18691976,20068231 ANAPC1 563 S Phosphorylation 18669648,19651622,20068231 ANAPC1 564 S Phosphorylation 19651622 ANAPC1 569 S Phosphorylation 18669648 ANAPC1 60 S Phosphorylation 18669648,20068231 ANAPC1 65 T Phosphorylation 18669648 ANAPC1 686 S Phosphorylation 16565220,18669648,18691976,19651622,20068231 ANAPC1 688 S Phosphorylation 16565220,18669648,18691976,19664995,19651622,19664994,18452278,18767875,19415658,20068231 ANAPC1 699 S Phosphorylation 18669648,19413330,18691976 ANAPC1 701 T Phosphorylation 17081983,18669648 ANAPC1 703 S Phosphorylation 17081983,18669648 ANAPC1 727 S Phosphorylation 19691289 ANAPC1 731 S Phosphorylation 19691289

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9H1A4 316 T 22067460 HTP Phosphorylation Q9H1A4 317 S 22067460 HTP Phosphorylation Q9H1A4 317 S 18669648 HTP Phosphorylation Q9H1A4 364 S 22067460 HTP Phosphorylation Q9H1A4 364 S 18669648 HTP Phosphorylation Q9H1A4 364 S 14657031 HTP Phosphorylation Q9H1A4 362 S 22067460 HTP Phosphorylation Q9H1A4 362 S 18669648 HTP Phosphorylation Q9H1A4 362 S 18220336 HTP Phosphorylation Q9H1A4 339 S 22067460 HTP Phosphorylation Q9H1A4 377 S 22067460 HTP Phosphorylation Q9H1A4 377 S 18220336 HTP Phosphorylation Q9H1A4 377 S 14657031 HTP Phosphorylation Q9H1A4 377 S 14657031 CDK1 LTP Phosphorylation Q9H1A4 377 S 14657031 PLK1 LTP Phosphorylation Q9H1A4 373 S 14657031 HTP Phosphorylation Q9H1A4 373 S 14657031 LTP Phosphorylation Q9H1A4 530 T 22067460 HTP Phosphorylation Q9H1A4 530 T 18669648 HTP Phosphorylation Q9H1A4 530 T 14657031 HTP Phosphorylation Q9H1A4 530 T 14657031 CDK1 LTP Phosphorylation Q9H1A4 530 T 14657031 PLK1 LTP Phosphorylation Q9H1A4 563 S 18669648 HTP Phosphorylation Q9H1A4 518 S 22067460 HTP Phosphorylation Q9H1A4 524 T 22067460 HTP Phosphorylation Q9H1A4 524 T 18669648 HTP Phosphorylation Q9H1A4 299 S 18669648 HTP Phosphorylation Q9H1A4 386 S 22067460 HTP Phosphorylation Q9H1A4 343 S 22067460 HTP Phosphorylation Q9H1A4 520 T 18669648 HTP Phosphorylation Q9H1A4 520 T 14657031 PLK1 HTP Phosphorylation Q9H1A4 522 S 22067460 HTP Phosphorylation Q9H1A4 307 S 18669648 HTP Phosphorylation Q9H1A4 916 S 22067460 HTP Phosphorylation Q9H1A4 65 T 22067460 HTP Phosphorylation Q9H1A4 65 T 18669648 HTP Phosphorylation Q9H1A4 555 S 22067460 HTP Phosphorylation Q9H1A4 555 S 14657031 CDK1 HTP Phosphorylation Q9H1A4 547 S 22067460 HTP Phosphorylation Q9H1A4 547 S 18669648 HTP Phosphorylation Q9H1A4 547 S 14657031 HTP Phosphorylation Q9H1A4 536 S 22067460 HTP Phosphorylation Q9H1A4 286 S 22067460 HTP Phosphorylation Q9H1A4 286 S 14657031 HTP Phosphorylation Q9H1A4 537 T 22067460 HTP Phosphorylation Q9H1A4 537 T 14657031 CDK1 HTP Phosphorylation Q9H1A4 51 S 22067460 HTP Phosphorylation Q9H1A4 51 S 18669648 HTP Phosphorylation Q9H1A4 703 S 22067460 HTP Phosphorylation Q9H1A4 703 S 18669648 HTP Phosphorylation Q9H1A4 688 S 22067460 HTP Phosphorylation Q9H1A4 688 S 18669648 HTP Phosphorylation Q9H1A4 688 S 14657031 HTP Phosphorylation Q9H1A4 688 S 15302935 HTP Phosphorylation Q9H1A4 688 S 14657031 CDK1 LTP Phosphorylation Q9H1A4 688 S 14657031 PLK1 LTP Phosphorylation Q9H1A4 686 S 22067460 HTP Phosphorylation Q9H1A4 686 S 18669648 HTP Phosphorylation Q9H1A4 686 S 14657031 PLK1 HTP Phosphorylation Q9H1A4 701 T 18669648 HTP Phosphorylation Q9H1A4 701 T 14657031 HTP Phosphorylation Q9H1A4 701 T 14657031 LTP Phosphorylation Q9H1A4 569 S 22067460 HTP Phosphorylation Q9H1A4 569 S 18669648 HTP Phosphorylation Q9H1A4 569 S 18220336 HTP Phosphorylation Q9H1A4 569 S 14657031 HTP Phosphorylation Q9H1A4 60 S 22067460 HTP Phosphorylation Q9H1A4 60 S 18669648 HTP Phosphorylation Q9H1A4 699 S 22067460 HTP Phosphorylation Q9H1A4 699 S 18669648 HTP Phosphorylation Q9H1A4 202 S 22067460 HTP Phosphorylation Q9H1A4 202 S 14657031 HTP Phosphorylation Q9H1A4 313 S 22067460 HTP Phosphorylation Q9H1A4 313 S 18669648 HTP Phosphorylation Q9H1A4 1347 S 22067460 HTP Phosphorylation Q9H1A4 341 S 18669648 HTP Phosphorylation Q9H1A4 333 S 22067460 HTP Phosphorylation Q9H1A4 291 T 22067460 HTP Phosphorylation Q9H1A4 291 T 18669648 HTP Phosphorylation Q9H1A4 291 T 14657031 HTP Phosphorylation Q9H1A4 291 T 14657031 CDK1 LTP Phosphorylation Q9H1A4 291 T 14657031 PLK1 LTP Phosphorylation Q9H1A4 334 S 22067460 HTP Phosphorylation Q9H1A4 351 S 22067460 HTP Phosphorylation Q9H1A4 731 S 22067460 HTP Phosphorylation Q9H1A4 731 S 14657031 HTP Phosphorylation Q9H1A4 731 S 15302935 HTP Phosphorylation Q9H1A4 355 S 22067460 HTP Phosphorylation Q9H1A4 355 S 18669648 HTP Phosphorylation Q9H1A4 355 S 18220336 HTP Phosphorylation Q9H1A4 355 S 14657031 HTP Phosphorylation Q9H1A4 355 S 14657031 CDK1 LTP Phosphorylation Q9H1A4 355 S 14657031 PLK1 LTP Phosphorylation Q9H1A4 571 Y 22067460 HTP Phosphorylation Q9H1A4 571 Y 14657031 HTP Phosphorylation Q9H1A4 529 S 22067460 HTP Phosphorylation Q9H1A4 529 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9H1A4 51 Phosphoserine 18669648 Q9H1A4 60 Phosphoserine 18669648;19690332;20068231 Q9H1A4 202 Phosphoserine 14657031 Q9H1A4 286 Phosphoserine 14657031 Q9H1A4 291 Phosphothreonine 18669648;20068231;23186163;14657031 Q9H1A4 313 Phosphoserine 23186163 Q9H1A4 341 Phosphoserine 18669648;20068231 Q9H1A4 343 Phosphoserine 23186163 Q9H1A4 355 Phosphoserine 18220336;18669648;20068231;23186163;14657031 Q9H1A4 362 Phosphoserine 18669648;23186163 Q9H1A4 373 Phosphoserine 14657031 Q9H1A4 377 Phosphoserine 18220336;18691976;20068231;21406692;23186163;14657031 Q9H1A4 537 Phosphothreonine 14657031 Q9H1A4 547 Phosphoserine 18669648;18691976;19690332;20068231 Q9H1A4 555 Phosphoserine 18691976;19690332;20068231 Q9H1A4 571 Phosphotyrosine 14657031 Q9H1A4 686 Phosphoserine 20068231 Q9H1A4 688 Phosphoserine 19690332;20068231;21406692;23186163;24275569;14657031 Q9H1A4 916 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type ANAPC1 IPI00033907 S 341 PSLHSRpSPSISNM phosphorylation ANAPC1 IPI00033907 S 355 ALSRAHpSPALGVH phosphorylation ANAPC1 IPI00033907 S 362 PALGVHpSFSGVQR phosphorylation ANAPC1 IPI00033907 S 364 LGVHSFpSGVQRFN phosphorylation ANAPC1 IPI00033907 S 372 VQRFNIpSSHNQSP phosphorylation ANAPC1 IPI00033907 S 377 ISSHNQpSPKRHSI phosphorylation ANAPC1 IPI00033907 S 50 PASELWpSSDGAAG phosphorylation ANAPC1 IPI00033907 S 51 ASELWSpSDGAAGL phosphorylation ANAPC1 IPI00033907 S 518 PGLPAPpSLTMSNT phosphorylation ANAPC1 IPI00033907 S 547 LSKLLGpSLDEVVL phosphorylation ANAPC1 IPI00033907 S 555 DEVVLLpSPVPELR phosphorylation ANAPC1 IPI00033907 S 563 VPELRDpSSKLHDS phosphorylation ANAPC1 IPI00033907 S 60 AAGLVGpSLQEVTI phosphorylation ANAPC1 IPI00033907 S 686 NFDFEGpSLSPVIA phosphorylation ANAPC1 IPI00033907 S 688 DFEGSLpSPVIAPK phosphorylation ANAPC1 IPI00033907 T 291 FSEQGGpTPQNVAT phosphorylation ANAPC1 IPI00033907 T 520 LPAPSLpTMSNTMP phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 64682 122229 - K Ubiquitination 21987572 64682 122229 - K Ubiquitination 21963094 64682 122229 - K Ubiquitination 21139048 64682 122229 - K Ubiquitination 21890473 64682 122229 - K Ubiquitination 21906983 64682 122229 - K Ubiquitination 22505724

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID ANAPC1 Homo sapiens (Human) 275; 1066; 69; 477; 429; 140; 905; 310; 694; 1709 "275,WTLRRVKSEEENV; 1066,HEFIEEKENRLLQ; 69,EVTIHEKQKESWQ; 477,VTNIPAKDAAPVE; 429,KNSQASKVFITSD; 140,SQDKSEKAYSSNE; 905,ITIAPQKLQVEQE; 310,HLRSLSKGDSPVT; 694,SPVIAPKKARPSE; 1709,AGQLSYKEDPMGW" "275:21906983; 1066:21906983; 69:21906983; 477:21906983; 429:21906983; 140:21906983; 905:21906983; 310:21890473,21906983; 694:21906983; 1709:21906983" ANAPC1 Homo sapiens (Human) 69 "69,EVTIHEKQKESWQ" 69:21906983