Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 8 92086094 92086094 + Silent SNP G G C TCGA-LT-A5Z6-01A-11D-A289-08 TCGA-LT-A5Z6-10A-01D-A289-08 g.chr8:92086094G>C c.360G>C c.(358-360)gtG>gtC p.V120V BLCA 8 92086102 92086102 + Missense_Mutation SNP A A G TCGA-PQ-A6FI-01A-11D-A31L-08 TCGA-PQ-A6FI-10A-01D-A31J-08 g.chr8:92086102A>G c.368A>G c.(367-369)aAt>aGt p.N123S BRCA 8 92082538 92082538 + Missense_Mutation SNP A A G TCGA-A2-A0T5-01A-21D-A099-09 TCGA-A2-A0T5-10A-01D-A099-09 g.chr8:92082538A>G c.16A>G c.(16-18)Agg>Ggg p.R6G BRCA 8 92082559 92082559 + Missense_Mutation SNP C C T TCGA-E9-A1NC-01A-12W-A16L-09 TCGA-E9-A1NC-10A-01D-A159-09 g.chr8:92082559C>T c.37C>T c.(37-39)Cct>Tct p.P13S CHOL 8 92096314 92096314 + Nonsense_Mutation SNP G G T TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 g.chr8:92096314G>T c.859G>T c.(859-861)Gaa>Taa p.E287* COAD 8 92082590 92082590 + Missense_Mutation SNP G G A TCGA-AZ-6601-01A-11D-1771-10 TCGA-AZ-6601-11A-01D-1771-10 g.chr8:92082590G>A c.68G>A c.(67-69)cGt>cAt p.R23H COAD 8 92090721 92090721 + Missense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr8:92090721G>T c.543G>T c.(541-543)caG>caT p.Q181H COAD 8 92090840 92090840 + Missense_Mutation SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr8:92090840T>C c.662T>C c.(661-663)gTg>gCg p.V221A COAD 8 92090886 92090886 + Missense_Mutation SNP G G A TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr8:92090886G>A c.708G>A c.(706-708)atG>atA p.M236I COAD 8 92096314 92096314 + Nonsense_Mutation SNP G G T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr8:92096314G>T c.859G>T c.(859-861)Gaa>Taa p.E287* COAD 8 92096322 92096322 + Frame_Shift_Del DEL A A - TCGA-AA-3833-01A-01W-0900-09 TCGA-AA-3833-10A-01W-0900-09 g.chr8:92096322delA c.867delA c.(865-867)tcafs p.S289fs COAD 8 92097012 92097012 + Splice_Site SNP A A T TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr8:92097012A>T c.888A>T c.(886-888)gtA>gtT p.V296V COADREAD 8 92082590 92082590 + Missense_Mutation SNP G G A TCGA-AZ-6601-01A-11D-1771-10 TCGA-AZ-6601-11A-01D-1771-10 g.chr8:92082590G>A c.68G>A c.(67-69)cGt>cAt p.R23H COADREAD 8 92082610 92082610 + Missense_Mutation SNP G G C TCGA-F5-6813-01A-11D-1826-10 TCGA-F5-6813-10A-01D-1826-10 g.chr8:92082610G>C c.88G>C c.(88-90)Gtc>Ctc p.V30L COADREAD 8 92083455 92083455 + Nonsense_Mutation SNP G G T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr8:92083455G>T c.262G>T c.(262-264)Gaa>Taa p.E88* COADREAD 8 92090721 92090721 + Missense_Mutation SNP G G T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr8:92090721G>T c.543G>T c.(541-543)caG>caT p.Q181H COADREAD 8 92090840 92090840 + Missense_Mutation SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr8:92090840T>C c.662T>C c.(661-663)gTg>gCg p.V221A COADREAD 8 92090886 92090886 + Missense_Mutation SNP G G A TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr8:92090886G>A c.708G>A c.(706-708)atG>atA p.M236I COADREAD 8 92096314 92096314 + Nonsense_Mutation SNP G G T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr8:92096314G>T c.859G>T c.(859-861)Gaa>Taa p.E287* COADREAD 8 92096322 92096322 + Frame_Shift_Del DEL A A - TCGA-AA-3833-01A-01W-0900-09 TCGA-AA-3833-10A-01W-0900-09 g.chr8:92096322delA c.867delA c.(865-867)tcafs p.S289fs COADREAD 8 92097012 92097012 + Splice_Site SNP A A T TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr8:92097012A>T c.888A>T c.(886-888)gtA>gtT p.V296V ESCA 8 92082604 92082604 + Silent SNP C C T TCGA-L5-A43E-01A-11D-A247-09 TCGA-L5-A43E-10A-01D-A247-09 g.chr8:92082604C>T c.82C>T c.(82-84)Ctg>Ttg p.L28L ESCA 8 92086058 92086058 + Splice_Site SNP G G C TCGA-Q9-A6FU-01A-11D-A31U-09 TCGA-Q9-A6FU-10A-01D-A31U-09 g.chr8:92086058G>C c.e3-1 ESCA 8 92090607 92090607 + Missense_Mutation SNP G G T TCGA-L5-A8NM-01A-11D-A37C-09 TCGA-L5-A8NM-11A-12D-A37F-09 g.chr8:92090607G>T c.429G>T c.(427-429)aaG>aaT p.K143N ESCA 8 92090640 92090640 + Silent SNP T T C TCGA-2H-A9GM-01A-11D-A37C-09 TCGA-2H-A9GM-11A-11D-A37F-09 g.chr8:92090640T>C c.462T>C c.(460-462)atT>atC p.I154I ESCA 8 92090650 92090650 + Missense_Mutation SNP A A G TCGA-L5-A43H-01A-11D-A247-09 TCGA-L5-A43H-11A-11D-A247-09 g.chr8:92090650A>G c.472A>G c.(472-474)Aca>Gca p.T158A ESCA 8 92097035 92097035 + Nonsense_Mutation SNP T T G TCGA-IG-A3I8-01A-11D-A247-09 TCGA-IG-A3I8-10A-01D-A247-09 g.chr8:92097035T>G c.911T>G c.(910-912)tTa>tGa p.L304* GBMLGG 8 92090721 92090721 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr8:92090721G>A c.543G>A c.(541-543)caG>caA p.Q181Q HNSC 8 92083370 92083370 + Missense_Mutation SNP A A T TCGA-BA-A4IG-01A-11D-A25Y-08 TCGA-BA-A4IG-10A-01D-A25Y-08 g.chr8:92083370A>T c.177A>T c.(175-177)aaA>aaT p.K59N HNSC 8 92083441 92083441 + Missense_Mutation SNP C C T TCGA-CN-5369-01A-01D-1434-08 TCGA-CN-5369-10A-01D-1434-08 g.chr8:92083441C>T c.248C>T c.(247-249)gCc>gTc p.A83V KIPAN 8 92083453 92083453 + Missense_Mutation SNP A A C TCGA-BP-5168-01A-01D-1421-08 TCGA-BP-5168-11A-01D-1421-08 g.chr8:92083453A>C c.260A>C c.(259-261)aAa>aCa p.K87T KIRC 8 92083453 92083453 + Missense_Mutation SNP A A C TCGA-BP-5168-01A-01D-1421-08 TCGA-BP-5168-11A-01D-1421-08 g.chr8:92083453A>C c.260A>C c.(259-261)aAa>aCa p.K87T LGG 8 92090721 92090721 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr8:92090721G>A c.543G>A c.(541-543)caG>caA p.Q181Q LIHC 8 92082521 92082620 + Start_Codon_Del DEL CATTTAAGTTTCTCGTCTTTGCAGTGGCTTTGCTTAGATCCGGTGCCGCCTTGAAGGCGGGGCTGGGTCCCAGCCGTAGCCAATGGAGCCCCGGGTGAGG CATTTAAGTTTCTCGTCTTTGCAGTGGCTTTGCTTAGATCCGGTGCCGCCTTGAAGGCGGGGCTGGGTCCCAGCCGTAGCCAATGGAGCCCCGGGTGAGG - TCGA-DD-A3A2-01A-11D-A20W-10 TCGA-DD-A3A2-11A-11D-A20W-10 g.chr8:92082521_92082620delCATTTAAGTTTCTCGTCTTTGCAGTGGCTTTGCTTAGATCCGGTGCCGCCTTGAAGGCGGGGCTGGGTCCCAGCCGTAGCCAATGGAGCCCCGGGTGAGG LUAD 8 92083505 92083505 + Silent SNP T T C TCGA-MP-A4T8-01A-11D-A24P-08 TCGA-MP-A4T8-10A-01D-A24P-08 g.chr8:92083505T>C c.312T>C c.(310-312)acT>acC p.T104T LUAD 8 92090700 92090700 + Silent SNP T T C TCGA-67-3772-01A-01W-0928-08 TCGA-67-3772-10A-01W-0928-08 g.chr8:92090700T>C c.522T>C c.(520-522)gcT>gcC p.A174A LUAD 8 92090719 92090719 + Missense_Mutation SNP C C G TCGA-17-Z030-01A-01W-0746-08 TCGA-17-Z030-11A-01W-0746-08 g.chr8:92090719C>G c.541C>G c.(541-543)Cag>Gag p.Q181E LUAD 8 92090777 92090777 + Missense_Mutation SNP A A T TCGA-78-7220-01A-11D-2036-08 TCGA-78-7220-10A-01D-2036-08 g.chr8:92090777A>T c.599A>T c.(598-600)aAg>aTg p.K200M LUAD 8 92090845 92090845 + Missense_Mutation SNP G G A TCGA-L4-A4E5-01A-11D-A24P-08 TCGA-L4-A4E5-10A-01D-A24P-08 g.chr8:92090845G>A c.667G>A c.(667-669)Gac>Aac p.D223N LUSC 8 92082567 92082567 + Missense_Mutation SNP C C G TCGA-60-2722-01A-01D-1522-08 TCGA-60-2722-11A-01D-1522-08 g.chr8:92082567C>G c.45C>G c.(43-45)agC>agG p.S15R LUSC 8 92092907 92092907 + Missense_Mutation SNP G G T TCGA-22-5473-01A-01D-1632-08 TCGA-22-5473-11A-11D-1632-08 g.chr8:92092907G>T c.729G>T c.(727-729)caG>caT p.Q243H OV 8 92082606 92082606 + Silent SNP G G T TCGA-10-0937-01A-02W-0419-10 TCGA-10-0937-11A-01W-0419-10 g.chr8:92082606G>T c.84G>T c.(82-84)ctG>ctT p.L28L PAAD 8 92097044 92097046 + In_Frame_Del DEL ATT ATT - TCGA-HZ-A49I-01A-12D-A26I-08 TCGA-HZ-A49I-10A-01D-A26I-08 g.chr8:92097044_92097046delATT c.920_922delATT c.(919-924)cattat>cat p.Y308del PRAD 8 92090653 92090653 + Missense_Mutation SNP G G A TCGA-HI-7169-01A-11D-2114-08 TCGA-HI-7169-10A-01D-2115-08 g.chr8:92090653G>A c.475G>A c.(475-477)Gga>Aga p.G159R READ 8 92082610 92082610 + Missense_Mutation SNP G G C TCGA-F5-6813-01A-11D-1826-10 TCGA-F5-6813-10A-01D-1826-10 g.chr8:92082610G>C c.88G>C c.(88-90)Gtc>Ctc p.V30L READ 8 92083455 92083455 + Nonsense_Mutation SNP G G T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr8:92083455G>T c.262G>T c.(262-264)Gaa>Taa p.E88* SARC 8 92096322 92096322 + Frame_Shift_Del DEL A A - TCGA-DX-A6B8-01A-11D-A307-09 TCGA-DX-A6B8-10A-01D-A307-09 g.chr8:92096322delA c.867delA c.(865-867)tcafs p.S289fs SKCM 8 92082560 92082560 + Missense_Mutation SNP C C T TCGA-D3-A5GU-06A-11D-A27K-08 TCGA-D3-A5GU-10A-01D-A27N-08 g.chr8:92082560C>T c.38C>T c.(37-39)cCt>cTt p.P13L

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 8 92083437 92083437 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant BLCA-CN 8 92083437 92083437 single base substitution G A exon_variant BLCA-CN 8 92083437 92083437 single base substitution G A missense_variant V82M 244G>A BRCA-EU 8 92079859 92079859 insertion of <=200bp - AT upstream_gene_variant BRCA-EU 8 92080118 92080118 single base substitution T C upstream_gene_variant BRCA-EU 8 92080543 92080543 single base substitution C T upstream_gene_variant BRCA-EU 8 92080612 92080612 single base substitution C A upstream_gene_variant BRCA-EU 8 92080668 92080668 single base substitution A C upstream_gene_variant BRCA-EU 8 92080830 92080830 single base substitution A C upstream_gene_variant BRCA-EU 8 92081609 92081609 single base substitution C T upstream_gene_variant BRCA-EU 8 92084100 92084100 single base substitution C T intron_variant BRCA-EU 8 92084219 92084219 single base substitution G T intron_variant BRCA-EU 8 92084433 92084433 single base substitution A G intron_variant BRCA-EU 8 92084474 92084474 deletion of <=200bp T - intron_variant BRCA-EU 8 92085752 92085752 single base substitution C A intron_variant BRCA-EU 8 92086009 92086009 single base substitution C A intron_variant BRCA-EU 8 92086233 92086233 deletion of <=200bp A - intron_variant BRCA-EU 8 92086920 92086920 single base substitution C G intron_variant BRCA-EU 8 92089055 92089055 single base substitution C A intron_variant BRCA-EU 8 92091033 92091033 single base substitution T A exon_variant BRCA-EU 8 92091033 92091033 single base substitution T A intron_variant BRCA-EU 8 92095111 92095111 insertion of <=200bp - T downstream_gene_variant BRCA-EU 8 92095111 92095111 insertion of <=200bp - T intron_variant BRCA-EU 8 92095564 92095564 deletion of <=200bp T - downstream_gene_variant BRCA-EU 8 92095564 92095564 deletion of <=200bp T - intron_variant BRCA-EU 8 92097061 92097061 single base substitution C T 3_prime_UTR_variant BRCA-EU 8 92097061 92097061 single base substitution C T missense_variant R182W 544C>T BRCA-EU 8 92097061 92097061 single base substitution C T missense_variant R313W 937C>T BRCA-EU 8 92098041 92098041 single base substitution T A 3_prime_UTR_variant BRCA-EU 8 92098041 92098041 single base substitution T A downstream_gene_variant BRCA-EU 8 92098042 92098042 single base substitution C T 3_prime_UTR_variant BRCA-EU 8 92098042 92098042 single base substitution C T downstream_gene_variant BRCA-EU 8 92099478 92099478 single base substitution A G downstream_gene_variant BRCA-EU 8 92099898 92099898 single base substitution G C downstream_gene_variant BRCA-EU 8 92100426 92100426 single base substitution C T downstream_gene_variant BRCA-EU 8 92100877 92100877 single base substitution C G downstream_gene_variant BRCA-EU 8 92101237 92101237 single base substitution G A downstream_gene_variant BRCA-EU 8 92102312 92102312 single base substitution C T downstream_gene_variant BRCA-EU 8 92104080 92104081 deletion of <=200bp AT - downstream_gene_variant BRCA-EU 8 92104184 92104184 single base substitution C T downstream_gene_variant BRCA-FR 8 92079988 92079988 single base substitution G C upstream_gene_variant BRCA-FR 8 92084108 92084108 single base substitution G A intron_variant BRCA-FR 8 92090790 92090790 single base substitution G A 3_prime_UTR_variant BRCA-FR 8 92090790 92090790 single base substitution G A exon_variant BRCA-FR 8 92090790 92090790 single base substitution G A synonymous_variant L204L 612G>A BRCA-FR 8 92090790 92090790 single base substitution G A synonymous_variant L73L 219G>A BRCA-FR 8 92098276 92098276 single base substitution C T 3_prime_UTR_variant BRCA-FR 8 92098276 92098276 single base substitution C T downstream_gene_variant BRCA-FR 8 92100237 92100237 single base substitution C T downstream_gene_variant BRCA-FR 8 92101237 92101237 single base substitution G A downstream_gene_variant BRCA-US 8 92082538 92082538 single base substitution A G missense_variant R6G 16A>G BRCA-US 8 92082538 92082538 single base substitution A G upstream_gene_variant BTCA-JP 8 92082509 92082509 single base substitution C G 5_prime_UTR_variant BTCA-JP 8 92082509 92082509 single base substitution C G upstream_gene_variant BTCA-JP 8 92088927 92088927 single base substitution A C 3_prime_UTR_variant BTCA-JP 8 92088927 92088927 single base substitution A C 5_prime_UTR_variant BTCA-JP 8 92088927 92088927 single base substitution A C exon_variant BTCA-JP 8 92088927 92088927 single base substitution A C intron_variant COAD-US 8 92082590 92082590 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant COAD-US 8 92082590 92082590 single base substitution G A exon_variant COAD-US 8 92082590 92082590 single base substitution G A missense_variant R23H 68G>A COAD-US 8 92086140 92086140 single base substitution G A splice_donor_variant COAD-US 8 92090721 92090721 single base substitution G T 3_prime_UTR_variant COAD-US 8 92090721 92090721 single base substitution G T exon_variant COAD-US 8 92090721 92090721 single base substitution G T missense_variant Q181H 543G>T COAD-US 8 92090721 92090721 single base substitution G T missense_variant Q50H 150G>T COAD-US 8 92090886 92090886 single base substitution G A 3_prime_UTR_variant COAD-US 8 92090886 92090886 single base substitution G A exon_variant COAD-US 8 92090886 92090886 single base substitution G A missense_variant M105I 315G>A COAD-US 8 92090886 92090886 single base substitution G A missense_variant M236I 708G>A COAD-US 8 92097012 92097012 single base substitution A T splice_region_variant COAD-US 8 92097062 92097062 single base substitution G A 3_prime_UTR_variant COAD-US 8 92097062 92097062 single base substitution G A missense_variant R182Q 545G>A COAD-US 8 92097062 92097062 single base substitution G A missense_variant R313Q 938G>A COCA-CN 8 92083230 92083230 single base substitution C T intron_variant COCA-CN 8 92090552 92090552 single base substitution G T intron_variant COCA-CN 8 92093619 92093619 single base substitution A C downstream_gene_variant COCA-CN 8 92093619 92093619 single base substitution A C intron_variant COCA-CN 8 92096169 92096169 single base substitution G A downstream_gene_variant COCA-CN 8 92096169 92096169 single base substitution G A intron_variant ESAD-UK 8 92077574 92077574 single base substitution T A upstream_gene_variant ESAD-UK 8 92080098 92080098 insertion of <=200bp - A upstream_gene_variant ESAD-UK 8 92081885 92081885 single base substitution C T upstream_gene_variant ESAD-UK 8 92083683 92083683 single base substitution T C intron_variant ESAD-UK 8 92085470 92085470 single base substitution A G intron_variant ESAD-UK 8 92086511 92086511 single base substitution A T intron_variant ESAD-UK 8 92088012 92088012 single base substitution G A intron_variant ESAD-UK 8 92088099 92088099 deletion of <=200bp A - intron_variant ESAD-UK 8 92090925 92090925 single base substitution T G exon_variant ESAD-UK 8 92090925 92090925 single base substitution T G intron_variant ESAD-UK 8 92091683 92091683 single base substitution G A downstream_gene_variant ESAD-UK 8 92091683 92091683 single base substitution G A intron_variant ESAD-UK 8 92092931 92092931 single base substitution C T 3_prime_UTR_variant ESAD-UK 8 92092931 92092931 single base substitution C T downstream_gene_variant ESAD-UK 8 92092931 92092931 single base substitution C T synonymous_variant N120N 360C>T ESAD-UK 8 92092931 92092931 single base substitution C T synonymous_variant N251N 753C>T ESAD-UK 8 92093566 92093566 single base substitution T A downstream_gene_variant ESAD-UK 8 92093566 92093566 single base substitution T A intron_variant ESAD-UK 8 92094227 92094227 single base substitution G T downstream_gene_variant ESAD-UK 8 92094227 92094227 single base substitution G T intron_variant ESAD-UK 8 92095174 92095174 single base substitution G A downstream_gene_variant ESAD-UK 8 92095174 92095174 single base substitution G A intron_variant ESAD-UK 8 92095596 92095596 single base substitution C T downstream_gene_variant ESAD-UK 8 92095596 92095596 single base substitution C T intron_variant ESAD-UK 8 92096646 92096646 single base substitution A G intron_variant ESAD-UK 8 92096930 92096930 insertion of <=200bp - TA intron_variant ESAD-UK 8 92098516 92098516 single base substitution C T 3_prime_UTR_variant ESAD-UK 8 92098516 92098516 single base substitution C T downstream_gene_variant ESAD-UK 8 92098538 92098538 single base substitution G A 3_prime_UTR_variant ESAD-UK 8 92098538 92098538 single base substitution G A downstream_gene_variant ESAD-UK 8 92100165 92100165 single base substitution G C downstream_gene_variant ESAD-UK 8 92100585 92100585 deletion of <=200bp A - downstream_gene_variant ESAD-UK 8 92101185 92101185 single base substitution G T downstream_gene_variant ESAD-UK 8 92101441 92101441 single base substitution G A downstream_gene_variant ESAD-UK 8 92101753 92101753 single base substitution T A downstream_gene_variant ESCA-CN 8 92092826 92092826 single base substitution A C downstream_gene_variant ESCA-CN 8 92092826 92092826 single base substitution A C intron_variant KIRC-US 8 92083453 92083453 single base substitution A C 5_prime_UTR_variant KIRC-US 8 92083453 92083453 single base substitution A C exon_variant KIRC-US 8 92083453 92083453 single base substitution A C missense_variant K87T 260A>C LICA-CN 8 92082565 92082565 single base substitution A T 5_prime_UTR_premature_start_codon_gain_variant LICA-CN 8 92082565 92082565 single base substitution A T exon_variant LICA-CN 8 92082565 92082565 single base substitution A T missense_variant S15C 43A>T LICA-CN 8 92082565 92082565 single base substitution A T upstream_gene_variant LICA-FR 8 92083426 92083426 single base substitution T G 5_prime_UTR_variant LICA-FR 8 92083426 92083426 single base substitution T G exon_variant LICA-FR 8 92083426 92083426 single base substitution T G missense_variant L78R 233T>G LICA-FR 8 92089516 92089516 single base substitution G A intron_variant LICA-FR 8 92097991 92097991 single base substitution A G 3_prime_UTR_variant LICA-FR 8 92097991 92097991 single base substitution A G downstream_gene_variant LICA-FR 8 92098618 92098618 single base substitution C T 3_prime_UTR_variant LICA-FR 8 92098618 92098618 single base substitution C T downstream_gene_variant LINC-JP 8 92079862 92079862 single base substitution T C upstream_gene_variant LINC-JP 8 92085766 92085766 single base substitution G A intron_variant LINC-JP 8 92089729 92089729 single base substitution A G intron_variant LINC-JP 8 92096243 92096243 single base substitution C T 3_prime_UTR_variant LINC-JP 8 92096243 92096243 single base substitution C T downstream_gene_variant LINC-JP 8 92096243 92096243 single base substitution C T missense_variant A132V 395C>T LINC-JP 8 92096243 92096243 single base substitution C T missense_variant A263V 788C>T LINC-JP 8 92098199 92098199 single base substitution A T 3_prime_UTR_variant LINC-JP 8 92098199 92098199 single base substitution A T downstream_gene_variant LIRI-JP 8 92078101 92078101 single base substitution A C upstream_gene_variant LIRI-JP 8 92079516 92079516 single base substitution T C upstream_gene_variant LIRI-JP 8 92081828 92081828 single base substitution C G upstream_gene_variant LIRI-JP 8 92082230 92082234 deletion of <=200bp AAATA - upstream_gene_variant LIRI-JP 8 92082900 92082900 single base substitution C A intron_variant LIRI-JP 8 92085434 92085434 single base substitution A G intron_variant LIRI-JP 8 92085692 92085692 insertion of <=200bp - T intron_variant LIRI-JP 8 92085917 92085917 single base substitution A G intron_variant LIRI-JP 8 92091139 92091139 single base substitution A G exon_variant LIRI-JP 8 92091139 92091139 single base substitution A G intron_variant LIRI-JP 8 92092025 92092025 single base substitution A G downstream_gene_variant LIRI-JP 8 92092025 92092025 single base substitution A G intron_variant LIRI-JP 8 92092438 92092438 single base substitution T A downstream_gene_variant LIRI-JP 8 92092438 92092438 single base substitution T A intron_variant LIRI-JP 8 92092774 92092774 single base substitution G T downstream_gene_variant LIRI-JP 8 92092774 92092774 single base substitution G T intron_variant LIRI-JP 8 92092879 92092879 single base substitution C G downstream_gene_variant LIRI-JP 8 92092879 92092879 single base substitution C G intron_variant LIRI-JP 8 92093619 92093619 single base substitution A C downstream_gene_variant LIRI-JP 8 92093619 92093619 single base substitution A C intron_variant LIRI-JP 8 92094524 92094524 single base substitution A G downstream_gene_variant LIRI-JP 8 92094524 92094524 single base substitution A G intron_variant LIRI-JP 8 92094926 92094926 single base substitution T G downstream_gene_variant LIRI-JP 8 92094926 92094926 single base substitution T G intron_variant LIRI-JP 8 92095356 92095356 single base substitution T G downstream_gene_variant LIRI-JP 8 92095356 92095356 single base substitution T G intron_variant LIRI-JP 8 92095537 92095537 single base substitution C T downstream_gene_variant LIRI-JP 8 92095537 92095537 single base substitution C T intron_variant LIRI-JP 8 92096470 92096470 single base substitution T G intron_variant LIRI-JP 8 92097837 92097837 single base substitution A G 3_prime_UTR_variant LIRI-JP 8 92097837 92097837 single base substitution A G downstream_gene_variant LIRI-JP 8 92098189 92098189 single base substitution A G 3_prime_UTR_variant LIRI-JP 8 92098189 92098189 single base substitution A G downstream_gene_variant LIRI-JP 8 92098774 92098774 single base substitution G A 3_prime_UTR_variant LIRI-JP 8 92098774 92098774 single base substitution G A downstream_gene_variant LIRI-JP 8 92099125 92099125 single base substitution T C 3_prime_UTR_variant LIRI-JP 8 92099125 92099125 single base substitution T C downstream_gene_variant LIRI-JP 8 92101220 92101220 single base substitution T G downstream_gene_variant LIRI-JP 8 92101285 92101285 single base substitution A G downstream_gene_variant LIRI-JP 8 92104262 92104262 single base substitution G A downstream_gene_variant LUSC-KR 8 92082281 92082281 single base substitution C T upstream_gene_variant LUSC-KR 8 92085485 92085485 single base substitution C G intron_variant LUSC-KR 8 92087615 92087615 single base substitution G C intron_variant LUSC-KR 8 92093760 92093760 single base substitution C T downstream_gene_variant LUSC-KR 8 92093760 92093760 single base substitution C T intron_variant LUSC-KR 8 92096109 92096109 single base substitution A G downstream_gene_variant LUSC-KR 8 92096109 92096109 single base substitution A G intron_variant LUSC-KR 8 92097692 92097692 single base substitution G T 3_prime_UTR_variant LUSC-KR 8 92097692 92097692 single base substitution G T downstream_gene_variant LUSC-KR 8 92097693 92097693 single base substitution G T 3_prime_UTR_variant LUSC-KR 8 92097693 92097693 single base substitution G T downstream_gene_variant LUSC-KR 8 92100732 92100732 single base substitution G T downstream_gene_variant LUSC-KR 8 92104124 92104124 single base substitution G A downstream_gene_variant LUSC-US 8 92082567 92082567 single base substitution C G 5_prime_UTR_variant LUSC-US 8 92082567 92082567 single base substitution C G exon_variant LUSC-US 8 92082567 92082567 single base substitution C G missense_variant S15R 45C>G LUSC-US 8 92082567 92082567 single base substitution C G upstream_gene_variant LUSC-US 8 92092907 92092907 single base substitution G T 3_prime_UTR_variant LUSC-US 8 92092907 92092907 single base substitution G T downstream_gene_variant LUSC-US 8 92092907 92092907 single base substitution G T missense_variant Q112H 336G>T LUSC-US 8 92092907 92092907 single base substitution G T missense_variant Q243H 729G>T MALY-DE 8 92081183 92081183 single base substitution T G upstream_gene_variant MALY-DE 8 92082144 92082144 deletion of <=200bp A - upstream_gene_variant MALY-DE 8 92082207 92082207 single base substitution G A upstream_gene_variant MALY-DE 8 92098540 92098540 single base substitution A C 3_prime_UTR_variant MALY-DE 8 92098540 92098540 single base substitution A C downstream_gene_variant MELA-AU 8 92077588 92077588 single base substitution G A upstream_gene_variant MELA-AU 8 92078028 92078028 single base substitution G A upstream_gene_variant MELA-AU 8 92078035 92078035 single base substitution G A upstream_gene_variant MELA-AU 8 92078601 92078601 single base substitution G T upstream_gene_variant MELA-AU 8 92079300 92079300 single base substitution G A upstream_gene_variant MELA-AU 8 92079301 92079301 single base substitution G A upstream_gene_variant MELA-AU 8 92080619 92080619 single base substitution T C upstream_gene_variant MELA-AU 8 92081106 92081106 single base substitution T A upstream_gene_variant MELA-AU 8 92082439 92082439 single base substitution C T 5_prime_UTR_variant MELA-AU 8 92082439 92082439 single base substitution C T upstream_gene_variant MELA-AU 8 92083516 92083516 single base substitution A T missense_variant K108M 323A>T MELA-AU 8 92083516 92083516 single base substitution A T splice_region_variant MELA-AU 8 92084096 92084096 single base substitution G A intron_variant MELA-AU 8 92084196 92084196 single base substitution C T intron_variant MELA-AU 8 92084351 92084351 single base substitution T A intron_variant MELA-AU 8 92084854 92084854 single base substitution T C intron_variant MELA-AU 8 92085333 92085333 single base substitution G A intron_variant MELA-AU 8 92085459 92085459 single base substitution A G intron_variant MELA-AU 8 92086052 92086052 single base substitution C T splice_region_variant MELA-AU 8 92086693 92086693 single base substitution T C intron_variant MELA-AU 8 92086916 92086916 single base substitution C T intron_variant MELA-AU 8 92087710 92087710 single base substitution C T intron_variant MELA-AU 8 92088177 92088177 single base substitution C T intron_variant MELA-AU 8 92088219 92088219 single base substitution G A intron_variant MELA-AU 8 92088403 92088403 single base substitution A G intron_variant MELA-AU 8 92088407 92088407 single base substitution C T intron_variant MELA-AU 8 92088852 92088852 single base substitution C T 3_prime_UTR_variant MELA-AU 8 92088852 92088852 single base substitution C T 5_prime_UTR_variant MELA-AU 8 92088852 92088852 single base substitution C T exon_variant MELA-AU 8 92088852 92088852 single base substitution C T intron_variant MELA-AU 8 92089328 92089328 single base substitution C T intron_variant MELA-AU 8 92089380 92089380 single base substitution T G intron_variant MELA-AU 8 92089749 92089749 single base substitution C T intron_variant MELA-AU 8 92090058 92090058 single base substitution T G intron_variant MELA-AU 8 92090726 92090726 single base substitution C T 3_prime_UTR_variant MELA-AU 8 92090726 92090726 single base substitution C T exon_variant MELA-AU 8 92090726 92090726 single base substitution C T missense_variant P183L 548C>T MELA-AU 8 92090726 92090726 single base substitution C T missense_variant P52L 155C>T MELA-AU 8 92091633 92091633 single base substitution C T downstream_gene_variant MELA-AU 8 92091633 92091633 single base substitution C T intron_variant MELA-AU 8 92091691 92091691 single base substitution G A downstream_gene_variant MELA-AU 8 92091691 92091691 single base substitution G A intron_variant MELA-AU 8 92093045 92093045 single base substitution C T downstream_gene_variant MELA-AU 8 92093045 92093045 single base substitution C T intron_variant MELA-AU 8 92093072 92093072 single base substitution C T downstream_gene_variant MELA-AU 8 92093072 92093072 single base substitution C T intron_variant MELA-AU 8 92093373 92093373 single base substitution G A downstream_gene_variant MELA-AU 8 92093373 92093373 single base substitution G A intron_variant MELA-AU 8 92093432 92093432 single base substitution C T downstream_gene_variant MELA-AU 8 92093432 92093432 single base substitution C T intron_variant MELA-AU 8 92094209 92094209 single base substitution C T downstream_gene_variant MELA-AU 8 92094209 92094209 single base substitution C T intron_variant MELA-AU 8 92094480 92094480 single base substitution C T downstream_gene_variant MELA-AU 8 92094480 92094480 single base substitution C T intron_variant MELA-AU 8 92094945 92094945 single base substitution T G downstream_gene_variant MELA-AU 8 92094945 92094945 single base substitution T G intron_variant MELA-AU 8 92095476 92095476 single base substitution A T downstream_gene_variant MELA-AU 8 92095476 92095476 single base substitution A T intron_variant MELA-AU 8 92095838 92095838 single base substitution C T downstream_gene_variant MELA-AU 8 92095838 92095838 single base substitution C T intron_variant MELA-AU 8 92095896 92095896 single base substitution T A downstream_gene_variant MELA-AU 8 92095896 92095896 single base substitution T A intron_variant MELA-AU 8 92097408 92097408 single base substitution C T 3_prime_UTR_variant MELA-AU 8 92097717 92097717 single base substitution G A 3_prime_UTR_variant MELA-AU 8 92097717 92097717 single base substitution G A downstream_gene_variant MELA-AU 8 92097926 92097927 multiple base substitution (>=2bp and <=200bp) CC TT 3_prime_UTR_variant MELA-AU 8 92097926 92097927 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 8 92099010 92099010 single base substitution C T 3_prime_UTR_variant MELA-AU 8 92099010 92099010 single base substitution C T downstream_gene_variant MELA-AU 8 92099382 92099382 single base substitution C T downstream_gene_variant MELA-AU 8 92099383 92099383 single base substitution C T downstream_gene_variant MELA-AU 8 92100880 92100880 single base substitution T A downstream_gene_variant MELA-AU 8 92100906 92100906 single base substitution A C downstream_gene_variant MELA-AU 8 92101096 92101096 single base substitution C T downstream_gene_variant MELA-AU 8 92101236 92101236 single base substitution G A downstream_gene_variant MELA-AU 8 92101544 92101544 single base substitution C T downstream_gene_variant MELA-AU 8 92101824 92101824 single base substitution C T downstream_gene_variant MELA-AU 8 92101933 92101933 single base substitution T C downstream_gene_variant MELA-AU 8 92102640 92102640 single base substitution C T downstream_gene_variant MELA-AU 8 92103202 92103202 single base substitution T A downstream_gene_variant MELA-AU 8 92103217 92103217 single base substitution C T downstream_gene_variant MELA-AU 8 92103239 92103239 single base substitution C T downstream_gene_variant MELA-AU 8 92104174 92104174 single base substitution C T downstream_gene_variant MELA-AU 8 92104226 92104226 single base substitution C T downstream_gene_variant ORCA-IN 8 92085930 92085930 single base substitution A G intron_variant ORCA-IN 8 92097053 92097053 single base substitution C A 3_prime_UTR_variant ORCA-IN 8 92097053 92097053 single base substitution C A stop_gained S179* 536C>A ORCA-IN 8 92097053 92097053 single base substitution C A stop_gained S310* 929C>A ORCA-IN 8 92098327 92098327 single base substitution C T 3_prime_UTR_variant ORCA-IN 8 92098327 92098327 single base substitution C T downstream_gene_variant OV-AU 8 92078780 92078780 single base substitution C T upstream_gene_variant OV-AU 8 92080105 92080105 single base substitution G T upstream_gene_variant OV-AU 8 92084989 92084989 single base substitution C T intron_variant OV-AU 8 92089102 92089102 single base substitution A G intron_variant OV-AU 8 92091939 92091939 single base substitution T C downstream_gene_variant OV-AU 8 92091939 92091939 single base substitution T C intron_variant OV-AU 8 92094915 92094915 single base substitution G A downstream_gene_variant OV-AU 8 92094915 92094915 single base substitution G A intron_variant OV-AU 8 92101637 92101637 single base substitution T C downstream_gene_variant OV-AU 8 92104240 92104240 single base substitution C T downstream_gene_variant PACA-AU 8 92078173 92078173 single base substitution C T upstream_gene_variant PACA-AU 8 92078592 92078592 single base substitution G A upstream_gene_variant PACA-AU 8 92084041 92084041 single base substitution T A intron_variant PACA-AU 8 92085442 92085442 single base substitution T C intron_variant PACA-AU 8 92085587 92085587 single base substitution G T intron_variant PACA-AU 8 92087672 92087672 single base substitution G A intron_variant PACA-AU 8 92090055 92090055 single base substitution C T intron_variant PACA-AU 8 92096113 92096113 single base substitution C T downstream_gene_variant PACA-AU 8 92096113 92096113 single base substitution C T intron_variant PACA-AU 8 92100458 92100464 deletion of <=200bp TTTCATT - downstream_gene_variant PACA-AU 8 92100970 92100970 single base substitution T A downstream_gene_variant PACA-CA 8 92078392 92078392 single base substitution C T upstream_gene_variant PACA-CA 8 92078574 92078574 single base substitution T A upstream_gene_variant PACA-CA 8 92082646 92082646 single base substitution G A 5_prime_UTR_variant PACA-CA 8 92082646 92082646 single base substitution G A exon_variant PACA-CA 8 92082646 92082646 single base substitution G A missense_variant E42K 124G>A PACA-CA 8 92083534 92083534 single base substitution T G intron_variant PACA-CA 8 92090856 92090856 single base substitution A G 3_prime_UTR_variant PACA-CA 8 92090856 92090856 single base substitution A G exon_variant PACA-CA 8 92090856 92090856 single base substitution A G synonymous_variant P226P 678A>G PACA-CA 8 92090856 92090856 single base substitution A G synonymous_variant P95P 285A>G PACA-CA 8 92091647 92091647 single base substitution T A downstream_gene_variant PACA-CA 8 92091647 92091647 single base substitution T A intron_variant PACA-CA 8 92092380 92092380 single base substitution C T downstream_gene_variant PACA-CA 8 92092380 92092380 single base substitution C T intron_variant PACA-CA 8 92099986 92099986 single base substitution T C downstream_gene_variant PACA-CA 8 92101283 92101283 single base substitution C T downstream_gene_variant PAEN-IT 8 92080629 92080629 single base substitution T C upstream_gene_variant PAEN-IT 8 92083613 92083613 single base substitution C T intron_variant PBCA-DE 8 92083041 92083041 single base substitution A T intron_variant PBCA-DE 8 92086859 92086859 single base substitution G T intron_variant PBCA-DE 8 92095960 92095960 single base substitution T G downstream_gene_variant PBCA-DE 8 92095960 92095960 single base substitution T G intron_variant PRAD-CA 8 92078867 92078867 single base substitution T C upstream_gene_variant PRAD-UK 8 92077836 92077836 single base substitution C T upstream_gene_variant PRAD-UK 8 92078854 92078854 single base substitution G A upstream_gene_variant PRAD-UK 8 92097118 92097118 single base substitution A G 3_prime_UTR_variant PRAD-UK 8 92099056 92099056 single base substitution T C 3_prime_UTR_variant PRAD-UK 8 92099056 92099056 single base substitution T C downstream_gene_variant PRAD-US 8 92090653 92090653 single base substitution G A 3_prime_UTR_variant PRAD-US 8 92090653 92090653 single base substitution G A exon_variant PRAD-US 8 92090653 92090653 single base substitution G A missense_variant G159R 475G>A PRAD-US 8 92090653 92090653 single base substitution G A missense_variant G28R 82G>A READ-US 8 92082610 92082610 single base substitution G C 5_prime_UTR_variant READ-US 8 92082610 92082610 single base substitution G C exon_variant READ-US 8 92082610 92082610 single base substitution G C missense_variant V30L 88G>C RECA-EU 8 92080456 92080456 single base substitution G T upstream_gene_variant RECA-EU 8 92085920 92085920 single base substitution G T intron_variant RECA-EU 8 92093263 92093263 single base substitution T A downstream_gene_variant RECA-EU 8 92093263 92093263 single base substitution T A intron_variant RECA-EU 8 92098861 92098861 single base substitution A T 3_prime_UTR_variant RECA-EU 8 92098861 92098861 single base substitution A T downstream_gene_variant SKCA-BR 8 92083571 92083571 single base substitution C T intron_variant SKCA-BR 8 92086244 92086244 single base substitution A T intron_variant SKCA-BR 8 92090687 92090687 single base substitution A T 3_prime_UTR_variant SKCA-BR 8 92090687 92090687 single base substitution A T exon_variant SKCA-BR 8 92090687 92090687 single base substitution A T missense_variant Q170L 509A>T SKCA-BR 8 92090687 92090687 single base substitution A T missense_variant Q39L 116A>T SKCA-BR 8 92091558 92091558 single base substitution C T downstream_gene_variant SKCA-BR 8 92091558 92091558 single base substitution C T intron_variant SKCA-BR 8 92092206 92092206 single base substitution C T downstream_gene_variant SKCA-BR 8 92092206 92092206 single base substitution C T intron_variant SKCA-BR 8 92093599 92093599 insertion of <=200bp - AAAAC downstream_gene_variant SKCA-BR 8 92093599 92093599 insertion of <=200bp - AAAAC intron_variant SKCA-BR 8 92096009 92096009 single base substitution C G downstream_gene_variant SKCA-BR 8 92096009 92096009 single base substitution C G intron_variant SKCA-BR 8 92097811 92097811 single base substitution C T 3_prime_UTR_variant SKCA-BR 8 92097811 92097811 single base substitution C T downstream_gene_variant SKCA-BR 8 92098385 92098385 single base substitution C T 3_prime_UTR_variant SKCA-BR 8 92098385 92098385 single base substitution C T downstream_gene_variant SKCM-US 8 92082560 92082560 single base substitution C T 5_prime_UTR_variant SKCM-US 8 92082560 92082560 single base substitution C T exon_variant SKCM-US 8 92082560 92082560 single base substitution C T missense_variant P13L 38C>T SKCM-US 8 92082560 92082560 single base substitution C T upstream_gene_variant STAD-US 8 92083383 92083383 single base substitution A G 5_prime_UTR_variant STAD-US 8 92083383 92083383 single base substitution A G exon_variant STAD-US 8 92083383 92083383 single base substitution A G missense_variant K64E 190A>G STAD-US 8 92090768 92090768 single base substitution T G 3_prime_UTR_variant STAD-US 8 92090768 92090768 single base substitution T G exon_variant STAD-US 8 92090768 92090768 single base substitution T G missense_variant L197R 590T>G STAD-US 8 92090768 92090768 single base substitution T G missense_variant L66R 197T>G UCEC-US 8 92082662 92082662 single base substitution G T 5_prime_UTR_variant UCEC-US 8 92082662 92082662 single base substitution G T exon_variant UCEC-US 8 92082662 92082662 single base substitution G T missense_variant R47I 140G>T UCEC-US 8 92083385 92083385 single base substitution G T 5_prime_UTR_variant UCEC-US 8 92083385 92083385 single base substitution G T exon_variant UCEC-US 8 92083385 92083385 single base substitution G T missense_variant K64N 192G>T UCEC-US 8 92083496 92083496 single base substitution G T 5_prime_UTR_variant UCEC-US 8 92083496 92083496 single base substitution G T exon_variant UCEC-US 8 92083496 92083496 single base substitution G T missense_variant K101N 303G>T UCEC-US 8 92097057 92097057 single base substitution T G 3_prime_UTR_variant UCEC-US 8 92097057 92097057 single base substitution T G synonymous_variant V180V 540T>G UCEC-US 8 92097057 92097057 single base substitution T G synonymous_variant V311V 933T>G

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand H23 COSM1196384 c.358G>T p.V120L Substitution - Missense 8:91073864-91073864 + S00472 COSM5658011 c.390A>T p.K130N Substitution - Missense 8:91073896-91073896 + TCGA-AA-A010-01 COSM283659 c.859G>T p.E287* Substitution - Nonsense 8:91084086-91084086 + TCGA-HI-7169-01 COSM1472207 c.385G>A p.G129R Substitution - Missense 8:91078425-91078425 + LP6005334-DNA_D02 COSM5035500 c.663C>T p.N221N Substitution - coding silent 8:91080703-91080703 + TCGA-A6-5665-01 COSM1458574 c.888A>T p.V296V Substitution - coding silent 8:91084784-91084784 + TCGA-AA-A010-01 COSM283658 c.769G>T p.E257* Substitution - Nonsense 8:91084086-91084086 + TCGA-CA-6717-01 COSM1458571 c.453G>T p.Q151H Substitution - Missense 8:91078493-91078493 + TCGA-CA-6717-01 COSM1458570 c.543G>T p.Q181H Substitution - Missense 8:91078493-91078493 + TCGA-AX-A0J0-01 COSM1102372 c.102G>T p.K34N Substitution - Missense 8:91071157-91071157 + 39 COSM5733787 c.399G>C p.K133N Substitution - Missense 8:91073905-91073905 + GHE0955 COSM5714909 c.638C>T p.T213I Substitution - Missense 8:91078588-91078588 + STC232 COSM5063371 c.189T>C p.H63H Substitution - coding silent 8:91071244-91071244 + STC291 COSM2790448 c.840G>A p.S280S Substitution - coding silent 8:91084826-91084826 + PCSI_0305_Pa_P_526 COSM3788113 c.34G>A p.E12K Substitution - Missense 8:91070418-91070418 + TCGA-D1-A16X-01 COSM1102369 c.140G>T p.R47I Substitution - Missense 8:91070434-91070434 + OSCC-GB_00390111 COSM3716056 c.839C>A p.S280* Substitution - Nonsense 8:91084825-91084825 + HCC98T COSM1624275 c.698C>T p.A233V Substitution - Missense 8:91084015-91084015 + TCGA-EI-6882-01 COSM5079494 c.343C>T p.R115* Substitution - Nonsense 8:91078383-91078383 + S02400 COSM5699975 c.343C>G p.R115G Substitution - Missense 8:91078383-91078383 + TCGA-B5-A11E-01 COSM1102373 c.303G>T p.K101N Substitution - Missense 8:91071268-91071268 + 112377 COSM96100 c.588A>G p.Q196Q Substitution - coding silent 8:91078538-91078538 + PCSI_0305_Pa_P_526 COSM3788112 c.124G>A p.E42K Substitution - Missense 8:91070418-91070418 + LUAD-S01405 COSM399254 c.796G>T p.V266L Substitution - Missense 8:91084113-91084113 + 477 COSM4438875 c.118G>C p.D40H Substitution - Missense 8:91070412-91070412 + Au1 COSM5597293 c.781-2A>T p.? Unknown 8:91084006-91084006 + Au1 COSM5597294 c.691-2A>T p.? Unknown 8:91084006-91084006 + TCGA-10-0937-01 COSM86645 c.84G>T p.L28L Substitution - coding silent 8:91070378-91070378 + TCGA-AX-A0J0-01 COSM1102371 c.192G>T p.K64N Substitution - Missense 8:91071157-91071157 + CSCC-41-T COSM4562945 c.94G>A p.E32K Substitution - Missense 8:91070388-91070388 + TCGA-A2-A0T5-01 COSM3835115 c.16A>G p.R6G Substitution - Missense 8:91070310-91070310 + HCC98 COSM1624275 c.698C>T p.A233V Substitution - Missense 8:91084015-91084015 + TCGA-G4-6302-01 COSM5174564 c.155_157delAGA p.K54delK Deletion - In frame 8:91070449-91070451 + 477 COSM4438876 c.28G>C p.D10H Substitution - Missense 8:91070412-91070412 + 451 COSM4435794 c.839C>T p.S280L Substitution - Missense 8:91084825-91084825 + XHDG31 COSM4769321 c.555G>T p.E185D Substitution - Missense 8:91078595-91078595 + 39 COSM5733788 c.309G>C p.K103N Substitution - Missense 8:91073905-91073905 + LP6005334-DNA_D02 COSM5035499 c.753C>T p.N251N Substitution - coding silent 8:91080703-91080703 + TCGA-BP-5168-01 COSM486744 c.170A>C p.K57T Substitution - Missense 8:91071225-91071225 + TCGA-HI-7169-01 COSM1472206 c.475G>A p.G159R Substitution - Missense 8:91078425-91078425 + TCGA-BG-A0M6-01 COSM1102375 c.438A>C p.E146D Substitution - Missense 8:91078388-91078388 + CSCC-41-T COSM4562946 c.4G>A p.E2K Substitution - Missense 8:91070388-91070388 + B25-Tumor COSM4006988 c.154G>A p.V52M Substitution - Missense 8:91071209-91071209 + HCC98 COSM1624274 c.788C>T p.A263V Substitution - Missense 8:91084015-91084015 + TCGA-AA-3833-01 COSM295095 c.777delA p.K261fs*3 Deletion - Frameshift 8:91084094-91084094 + TCGA-BP-5168-01 COSM486743 c.260A>C p.K87T Substitution - Missense 8:91071225-91071225 + 273T COSM1727375 c.46C>T p.R16W Substitution - Missense 8:91070340-91070340 + PCSI_0279_Pa_P_526 COSM3788115 c.588A>G p.P196P Substitution - coding silent 8:91078628-91078628 + TCGA-EI-6882-01 COSM5079493 c.433C>T p.R145* Substitution - Nonsense 8:91078383-91078383 + TCGA-BR-8368-01 COSM3902009 c.100A>G p.K34E Substitution - Missense 8:91071155-91071155 + TCGA-HU-8602-01 COSM3902010 c.590T>G p.L197R Substitution - Missense 8:91078540-91078540 + STC232 COSM5063372 c.734A>G p.Y245C Substitution - Missense 8:91080684-91080684 + NOKSI COSM4595647 c.304C>G p.L102V Substitution - Missense 8:91071269-91071269 + SNU-C4 COSM295096 c.867delA p.K291fs*3 Deletion - Frameshift 8:91084094-91084094 + TCGA-22-5473-01 COSM751475 c.729G>T p.Q243H Substitution - Missense 8:91080679-91080679 + 39T COSM3716055 c.929C>A p.S310* Substitution - Nonsense 8:91084825-91084825 + LUAD_E00565 COSM389667 c.203A>C p.E68A Substitution - Missense 8:91071258-91071258 + S02400 COSM5699974 c.433C>G p.R145G Substitution - Missense 8:91078383-91078383 + CSCC-44-T COSM4486943 c.311C>T p.T104I Substitution - Missense 8:91071276-91071276 + T3062 COSM4710579 c.18C>G p.T6T Substitution - coding silent 8:91070402-91070402 + HCC021T COSM5815425 c.43A>T p.S15C Substitution - Missense 8:91070337-91070337 + CSCC-44-T COSM4486944 c.221C>T p.T74I Substitution - Missense 8:91071276-91071276 + B25-Tumor COSM4006987 c.244G>A p.V82M Substitution - Missense 8:91071209-91071209 + XHDG31 COSM4769320 c.645G>T p.E215D Substitution - Missense 8:91078595-91078595 + TCGA-CK-5916-01 COSM3763445 c.938G>A p.R313Q Substitution - Missense 8:91084834-91084834 + PCSI_0279_Pa_P_526 COSM3788114 c.678A>G p.P226P Substitution - coding silent 8:91078628-91078628 + TCGA-D1-A16X-01 COSM1102370 c.50G>T p.R17I Substitution - Missense 8:91070434-91070434 + TCGA-60-2722-01 COSM751477 c.45C>G p.S15R Substitution - Missense 8:91070339-91070339 + TP_2034 COSM5548066 c.83-7delT p.? Unknown 8:91071131-91071131 + TCGA-D1-A17Q-01 COSM1102377 c.933T>G p.V311V Substitution - coding silent 8:91084829-91084829 + TCGA-F5-6813-01 COSM1569510 c.88G>C p.V30L Substitution - Missense 8:91070382-91070382 + TCGA-BR-8368-01 COSM3902008 c.190A>G p.K64E Substitution - Missense 8:91071155-91071155 + BCM423T COSM4802622 c.143T>G p.L48R Substitution - Missense 8:91071198-91071198 + 451 COSM4435793 c.929C>T p.S310L Substitution - Missense 8:91084825-91084825 + TCGA-AG-A002-01 COSM262702 c.172G>T p.E58* Substitution - Nonsense 8:91071227-91071227 + STC232 COSM5063373 c.644A>G p.Y215C Substitution - Missense 8:91080684-91080684 + HCC98T COSM1624274 c.788C>T p.A263V Substitution - Missense 8:91084015-91084015 + TCGA-B5-A11E-01 COSM1102374 c.213G>T p.K71N Substitution - Missense 8:91071268-91071268 + 381_T COSM3952033 c.62T>C p.L21P Substitution - Missense 8:91070356-91070356 + TCGA-A6-5665-01 COSM1458575 c.798A>T p.V266V Substitution - coding silent 8:91084784-91084784 + TCGA-AA-3833-01 COSM295096 c.867delA p.K291fs*3 Deletion - Frameshift 8:91084094-91084094 + BCM423T COSM4802621 c.233T>G p.L78R Substitution - Missense 8:91071198-91071198 + 112638 COSM94894 c.384A>G p.I128M Substitution - Missense 8:91073890-91073890 + 112377 COSM96099 c.498A>G p.Q166Q Substitution - coding silent 8:91078538-91078538 + TCGA-22-5473-01 COSM751476 c.639G>T p.Q213H Substitution - Missense 8:91080679-91080679 + TCGA-G4-6302-01 COSM3699207 c.405+1G>A p.? Unknown 8:91073912-91073912 + NOKSI COSM4595648 c.214C>G p.L72V Substitution - Missense 8:91071269-91071269 + 112638 COSM94893 c.294A>G p.I98M Substitution - Missense 8:91073890-91073890 + TP_2034 COSM5548065 c.173-7delT p.? Unknown 8:91071131-91071131 + TCGA-D1-A17Q-01 COSM1102378 c.843T>G p.V281V Substitution - coding silent 8:91084829-91084829 + 39T COSM3716056 c.839C>A p.S280* Substitution - Nonsense 8:91084825-91084825 + BCM423T COSM4802622 c.143T>G p.L48R Substitution - Missense 8:91071198-91071198 + TCGA-AD-6964-01 COSM1458573 c.618G>A p.M206I Substitution - Missense 8:91078658-91078658 + T3062 COSM4710578 c.108C>G p.T36T Substitution - coding silent 8:91070402-91070402 + TCGA-BG-A0M6-01 COSM1102376 c.348A>C p.E116D Substitution - Missense 8:91078388-91078388 + SNU-C4 COSM295095 c.777delA p.K261fs*3 Deletion - Frameshift 8:91084094-91084094 + STC291 COSM2790447 c.930G>A p.S310S Substitution - coding silent 8:91084826-91084826 + LUAD_E00565 COSM389666 c.293A>C p.E98A Substitution - Missense 8:91071258-91071258 + ME029T COSM226636 c.703T>C p.S235P Substitution - Missense 8:91084020-91084020 + TCGA-AD-6964-01 COSM1458572 c.708G>A p.M236I Substitution - Missense 8:91078658-91078658 + TCGA-HU-8602-01 COSM3902011 c.500T>G p.L167R Substitution - Missense 8:91078540-91078540 + LUAD-S01405 COSM399253 c.886G>T p.V296L Substitution - Missense 8:91084113-91084113 + STC232 COSM5063370 c.279T>C p.H93H Substitution - coding silent 8:91071244-91071244 + GHE0955 COSM5714910 c.548C>T p.T183I Substitution - Missense 8:91078588-91078588 + TCGA-AG-A002-01 COSM262703 c.262G>T p.E88* Substitution - Nonsense 8:91071227-91071227 + TCGA-G4-6302-01 COSM3699208 c.315+1G>A p.? Unknown 8:91073912-91073912 + TCGA-AZ-6601-01 COSM1458569 c.68G>A p.R23H Substitution - Missense 8:91070362-91070362 + TCGA-D3-A5GU-06 COSM3651663 c.38C>T p.P13L Substitution - Missense 8:91070332-91070332 + S00472 COSM5658012 c.300A>T p.K100N Substitution - Missense 8:91073896-91073896 + OSCC-GB_00390111 COSM3716055 c.929C>A p.S310* Substitution - Nonsense 8:91084825-91084825 + BCM423T COSM4802621 c.233T>G p.L78R Substitution - Missense 8:91071198-91071198 + TCGA-CK-5916-01 COSM3763446 c.848G>A p.R283Q Substitution - Missense 8:91084834-91084834 + H23 COSM1196385 c.268G>T p.V90L Substitution - Missense 8:91073864-91073864 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.30509;Hs.30532 8q21.3 612021

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C 3-UTRSNV . c.969+2A>C 8 92097095 ALL A C Missense p.K87T c.260A>C 8 92083453 RCCC A G 3-UTRSNV . c.969+1096A>G 8 92098189 HC A G 3-UTRSNV . c.969+744A>G 8 92097837 HC C G Missense p.Q181E c.541C>G 8 92090719 LUAD C G Missense p.S15R c.45C>G 8 92082567 LUSC C T Missense p.A83V c.248C>T 8 92083441 HNSC C T Missense p.P13S c.37C>T 8 92082559 BRCA G A Missense p.G159R c.475G>A 8 92090653 PRAD G T Missense p.Q243H c.729G>T 8 92092907 LUSC G T Synonymous p.L28L c.84G>T 8 92082606 OV T C Synonymous p.A174A c.522T>C 8 92090700 LUAD