PTM - CPLM Gene Name UniProt ID Type Position Code NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 80 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 125 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 130 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 114 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 134 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 107 K NSMCE2; C8orf36; MMS21 Q96MF7 Ubiquitination 101 K

PTM - dbPAF Gene Name UniProt ID Position Type Species NSMCE2; C8orf36; MMS21 Q96MF7 11 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 113 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 116 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 12 T Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 209 Y Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 216 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 22 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 223 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 26 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 5 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 6 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 7 S Homo sapiens(Human) NSMCE2; C8orf36; MMS21 Q96MF7 9 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q96MF7 K125-ac Acetylation ADFQNNEkFVQFkQQ Q96MF7 S7-p Phosphorylation _MPGRSSsNSGSTGF Q96MF7 S113-p Phosphorylation KkFLALQskNsDADF Q96MF7 S116-p Phosphorylation LALQskNsDADFQNN Q96MF7 Y209-p Phosphorylation QKRKKKAyCPQIGCs Q96MF7 S216-p Phosphorylation yCPQIGCsHTDIRks Q96MF7 S223-p Phosphorylation sHTDIRksDLIQDEA Q96MF7 K90-sm Sumoylation QSTINHVkEERPEKI Q96MF7 K101-sm Sumoylation PEKIPDLkLLVEKkF Q96MF7 K107-sm Sumoylation LkLLVEKkFLALQsk Q96MF7 K125-sm Sumoylation ADFQNNEkFVQFkQQ Q96MF7 K130-sm Sumoylation NEkFVQFkQQLKELK Q96MF7 K222-sm Sumoylation CsHTDIRksDLIQDE Q96MF7 K80-ub Ubiquitination RQLNHYVkAVQSTIN Q96MF7 K101-ub Ubiquitination PEKIPDLkLLVEKkF Q96MF7 K114-ub Ubiquitination kFLALQskNsDADFQ Q96MF7 K125-ub Ubiquitination ADFQNNEkFVQFkQQ Q96MF7 K130-ub Ubiquitination NEkFVQFkQQLKELK Q96MF7 K183-ub Ubiquitination MKKPVKNkVCGHTYE Q96MF7 K222-ub Ubiquitination CsHTDIRksDLIQDE

PTM - dbPTM UniProt ID Position Code Type Resources References Q96MF7 209 Y Phosphorylation Swiss-Prot 1010711 17924679 Q96MF7 216 S Phosphorylation Swiss-Prot 1010711 17924679 Q96MF7 12 T Phosphorylation PhosphoELM.10011 18669648 Q96MF7 5 S Phosphorylation HPRD 9.0 20068231 Q96MF7 6 S Phosphorylation HPRD 9.0 20068231 Q96MF7 7 S Phosphorylation HPRD 9.0 20068231 Q96MF7 11 S Phosphorylation HPRD 9.0 20068231 Q96MF7 22 S Phosphorylation HPRD 9.0 20068231 Q96MF7 26 S Phosphorylation HPRD 9.0 20068231 Q96MF7 216 S Phosphorylation HPRD 9.0 17924679 Q96MF7 12 T Phosphorylation HPRD 9.0 18669648,20068231 Q96MF7 209 Y Phosphorylation HPRD 9.0 17924679

PTM - HPRD Symbol Position Code Type References NSMCE2 11 S Phosphorylation 20068231 NSMCE2 12 T Phosphorylation 18669648,20068231 NSMCE2 209 Y Phosphorylation 17924679 NSMCE2 216 S Phosphorylation 17924679 NSMCE2 22 S Phosphorylation 20068231 NSMCE2 26 S Phosphorylation 20068231 NSMCE2 5 S Phosphorylation 20068231 NSMCE2 6 S Phosphorylation 20068231 NSMCE2 7 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q96MF7 12 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q96MF7 1 N-acetylmethionine 20068231 Q96MF7 116 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type NSMCE2 IPI00166784 S 6 _MPGRSpSSNSGST phosphorylation NSMCE2 IPI00166784 S 7 MPGRSSpSNSGSTG phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 286053 130282 - K Sumoylation 21693764 286053 130282 - K Ubiquitination 21139048 286053 130282 - K Ubiquitination 21890473 286053 130282 - K Ubiquitination 21906983 286053 130282 - K Sumoylation 19471022 286053 130282 - K Sumoylation 18086888 286053 130282 - K Ubiquitination 23000965 286053 130282 - K Sumoylation 25391492

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID NSMCE2 Homo sapiens (Human) 80; 114; 125; 130 "80,QLNHYVKAVQSTI; 114,FLALQSKNSDADF; 125,DFQNNEKFVQFKQ; 130,EKFVQFKQQLKEL" "80:21890473; 114:21906983; 125:21890473,21906983; 130:21890473"