Disease associated variation - GWASdb |
Chr | Pos | SNP ID(dbSNP 142) | Ref | Alt | Ori SNP ID | P-value | Drug Name | Drug Anno | GWAS Trait | HPO ID | DO ID | AA | Type | Trait or Drug |
10 | 28347988 | rs2252206 | A | G | rs2252206 | 0.000795 | METHIONINE | CASPASE 1|CASPASE 9|CASP9 PROTEIN, HUMAN|5'-METHYLTHIOADENOSINE|APIP PROTEIN, HUMAN|DEOXYADENOSINES|THIONUCLEOSIDES|APOPTOSIS REGULATORY PROTEINS | Salmonella-induced pyroptosis | NA | NA | G | intron | GWASdb_drug |
10 | 28353751 | rs7909706 | T | C | rs7909706 | 6.30E-05 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | T | intron | GWASdb_drug |
10 | 28391617 | rs4749306 | C | G | rs4749306 | 1.49E-04 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_drug |
10 | 28393824 | rs10826398 | G | T | rs10826398 | 1.67E-05 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_drug |
10 | 28424177 | rs4317882 | G | A | rs4317882 | 7.51E-05 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_drug |
10 | 28432044 | rs4506531 | C | G | rs4506531 | 7.51E-05 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_drug |
10 | 28450599 | rs2985523 | T | G | rs2985523 | 3.16E-04 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | A | intron | GWASdb_drug |
10 | 28470732 | rs11006913 | A | G | rs11006913 | 6.39E-05 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | A | intron | GWASdb_drug |
10 | 28475495 | rs2985535 | C | T | rs2985535 | 2.75E-04 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_drug |
10 | 28476148 | rs1937809 | C | T | rs1937809 | 2.75E-04 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | T | intron | GWASdb_drug |
10 | 28489647 | rs7922685 | C | G | rs7922685 | 1.02E-04 | CISPLATIN|ETOPOSIDE|CARBOPLATIN | R-SNARE PROTEINS|PLATINUM|STXBP5 PROTEIN, HUMAN|NERVE TISSUE PROTEINS | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_drug |
10 | 28541472 | rs1870097 | T | C | rs1870097 | 8.31E-04 | ATORVASTATIN | SERINE ENDOPEPTIDASES|PYRROLES|PCSK9 PROTEIN, HUMAN|HEPTANOIC ACIDS|APOLIPOPROTEINS E|PROPROTEIN CONVERTASES | Response to statin treatment (atorvastatin), change in cholesterol levels | HPOID:0001626 | DOID:1287 | A | intron | GWASdb_drug |
10 | 28346035 | rs7920857 | G | C | rs7920857 | 3.27E-04 | | | Insulin resistance | HPOID:0000855 | DOID:9352 | G | intron | GWASdb_trait |
10 | 28347988 | rs2252206 | A | G | rs2252206 | 0.000795 | | | Salmonella-induced pyroptosis | NA | NA | G | intron | GWASdb_trait |
10 | 28353751 | rs7909706 | T | C | rs7909706 | 6.30E-05 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | T | intron | GWASdb_trait |
10 | 28373644 | rs4749301 | T | C | rs4749301 | 5.80E-04 | | | Alcohol dependence | HPOID:0000707 | DOID:0050741 | T | intron | GWASdb_trait |
10 | 28382933 | rs927675 | A | C | rs927675 | 2.00E-06 | | | MRI atrophy measures | HPOID:0001626 | DOID:10652 | T | intron | GWASdb_trait |
10 | 28388150 | rs10763642 | G | A | rs10763642 | 7.00E-06 | | | Obesity-related traits | HPOID:0001513 | DOID:9970 | G | intron | GWASdb_trait |
10 | 28391617 | rs4749306 | C | G | rs4749306 | 1.49E-04 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_trait |
10 | 28393824 | rs10826398 | G | T | rs10826398 | 9.81E-05 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
10 | 28393824 | rs10826398 | G | T | rs10826398 | 1.67E-05 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_trait |
10 | 28400835 | rs12776665 | C | A | rs12776665 | 2.57E-06 | | | Total ventricular volume | HPOID:0001627 | DOID:10652 | C | intron | GWASdb_trait |
10 | 28415164 | rs2490062 | A | T | rs2490062 | 0.0000612 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | T | intron | GWASdb_trait |
10 | 28424177 | rs4317882 | G | A | rs4317882 | 7.51E-05 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_trait |
10 | 28432044 | rs4506531 | C | G | rs4506531 | 9.96E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | C | intron | GWASdb_trait |
10 | 28432044 | rs4506531 | C | G | rs4506531 | 7.51E-05 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_trait |
10 | 28438930 | rs147999424 | G | A | rs147999424 | 0.000038 | | | Breast cancer (ER positive) | HPOID:0003002 | DOID:1612 | G | missense | GWASdb_trait |
10 | 28442841 | rs9299597 | G | A | rs9299597 | 0.000634026 | | | Hypertension (early onset hypertension) | HPOID:0000822 | DOID:10763 | G | intron | GWASdb_trait |
10 | 28446745 | rs2985532 | T | C | rs2985532 | 0.0000556 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | T | intron | GWASdb_trait |
10 | 28449974 | rs7081378 | G | A | rs7081378 | 8.74E-04 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | G | intron | GWASdb_trait |
10 | 28450599 | rs2985523 | T | G | rs2985523 | 3.16E-04 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | A | intron | GWASdb_trait |
10 | 28450599 | rs2985523 | T | G | rs2985523 | 0.0000632 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | A | intron | GWASdb_trait |
10 | 28451249 | rs12254584 | C | A | rs12254584 | 4.04E-04 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | C | intron | GWASdb_trait |
10 | 28451289 | rs2985522 | T | C | rs2985522 | 0.0000343 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | A | intron | GWASdb_trait |
10 | 28451524 | rs1626856 | T | A | rs1626856 | 0.0000665 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | A | intron | GWASdb_trait |
10 | 28452867 | rs1781832 | T | C | rs1781832 | 0.0000677 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | C | intron | GWASdb_trait |
10 | 28453046 | rs2763316 | A | G | rs2763316 | 0.0000684 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | A | intron | GWASdb_trait |
10 | 28453145 | rs1781833 | G | C | rs1781833 | 0.0000685 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | G | intron | GWASdb_trait |
10 | 28453225 | rs1781834 | T | C | rs1781834 | 0.0000684 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | C | intron | GWASdb_trait |
10 | 28453354 | rs1781835 | T | C | rs1781835 | 0.0000684 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | T | intron | GWASdb_trait |
10 | 28453677 | rs1748484 | T | A | rs1748484 | 0.000074 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | T | intron | GWASdb_trait |
10 | 28453966 | rs2801843 | A | C,G,T | rs2801843 | 0.0000895 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | C | intron | GWASdb_trait |
10 | 28453981 | rs2801844 | G | T | rs2801844 | 0.0000688 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | T | intron | GWASdb_trait |
10 | 28454152 | rs2801845 | A | T | rs2801845 | 8.20E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
10 | 28454533 | rs7085245 | T | G | rs7085245 | 3.52E-04 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | T | intron | GWASdb_trait |
10 | 28454570 | rs7101051 | C | A | rs7101051 | 9.33E-04 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | A | intron | GWASdb_trait |
10 | 28455529 | rs2985517 | T | C | rs2985517 | 0.0000673 | | | Nonsyndromic striae distensae (stretch marks) | HPOID:0001000 | DOID:37 | A | intron | GWASdb_trait |
10 | 28462933 | rs2887214 | T | A | rs2887214 | 3.55E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | A | intron | GWASdb_trait |
10 | 28466013 | rs7914949 | T | C | rs7914949 | 2.00E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | C | intron | GWASdb_trait |
10 | 28466881 | rs35494924 | T | C | rs35494924 | 2.68E-06 | | | Bone mineral density | HPOID:0004348 | DOID:0080011 | T | intron | GWASdb_trait |
10 | 28470732 | rs11006913 | A | G | rs11006913 | 6.39E-05 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | A | intron | GWASdb_trait |
10 | 28475495 | rs2985535 | C | T | rs2985535 | 2.75E-04 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | G | intron | GWASdb_trait |
10 | 28476148 | rs1937809 | C | T | rs1937809 | 3.36E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | T | intron | GWASdb_trait |
10 | 28476148 | rs1937809 | C | T | rs1937809 | 2.75E-04 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | T | intron | GWASdb_trait |
10 | 28479942 | rs3905706 | C | T | rs3905706 | 2.00E-16 | | | Bone mineral density | HPOID:0004348 | DOID:0080011 | G | intron | GWASdb_trait |
10 | 28479942 | rs3905706 | C | T | rs3905706 | 8.00E-06 | | | Bone mineral density | HPOID:0004348 | DOID:0080011 | G | intron | GWASdb_trait |
10 | 28479942 | rs3905706 | C | T | rs3905706 | 2.93E-06 | | | Bone mineral density (paediatric, skull) | HPOID:0004348 | DOID:0080011 | G | intron | GWASdb_trait |
10 | 28479942 | rs3905706 | C | T | rs3905706 | 3.00E-06 | | | Bone mineral density (paediatric, skull) | HPOID:0004348 | DOID:0080011 | G | intron | GWASdb_trait |
10 | 28489647 | rs7922685 | C | G | rs7922685 | 1.02E-04 | | | Response to platinum-based chemotherapy in small-cell lung cancer | HPOID:0100526 | DOID:5409 | C | intron | GWASdb_trait |
10 | 28504944 | rs11006923 | T | C | rs11006923 | 9.00E-06 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | T | intron | GWASdb_trait |
10 | 28514249 | rs11006928 | A | T | rs11006928 | 1.04E-05 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | A | intron | GWASdb_trait |
10 | 28515799 | rs17831816 | G | A | rs17831816 | 9.19E-06 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | G | intron | GWASdb_trait |
10 | 28540477 | rs11006950 | C | G | rs11006950 | 1.02E-04 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | C | intron | GWASdb_trait |
10 | 28541472 | rs1870097 | T | C | rs1870097 | 8.31E-04 | | | Response to statin treatment (atorvastatin), change in cholesterol levels | HPOID:0001626 | DOID:1287 | A | intron | GWASdb_trait |
10 | 28544070 | rs11006958 | A | C | rs11006958 | 1.32E-05 | | | Alzheimer's disease | HPOID:0002511 | DOID:10652 | A | intron | GWASdb_trait |
10 | 28560451 | rs7086943 | T | C | rs7086943 | 6.14E-04 | | | Insulin resistance | HPOID:0000855 | DOID:9352 | T | intron | GWASdb_trait |
10 | 28567807 | rs7905490 | C | T | rs7905490 | 3.22E-04 | | | Acute lung injury | HPOID:0002088 | DOID:850 | T | intron | GWASdb_trait |