PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BANF1 CHAF1B 19759913 biogrid exp P P P GP G P P GP RPL10 CHAF1B 26496610 biogrid,intact exp P P P P P P P SOX2 CHAF1B 23667531 biogrid exp P P P GP P P GP INSL3 CHAF1B 26186194 biogrid exp GP CHAF1B FBXW11 25515538 biogrid exp G G G MYC CHAF1B 21150319 i2d,intact exp P P P GP G P P GP CHAF1B SMAD4 25609649 intact exp P P GP G P P GP CHAF1B CHAF1B 19410544 intact exp P P P GP G P P GP CHAF1B CCDC8 24711643 biogrid exp P P P GP G P P GP OBSL1 CHAF1B 24711643 biogrid exp P P GP G P P GP CHAF1B CNOT6L 17452450 biogrid,intact exp P GP G P P G RBPJ CHAF1B 25609649 intact exp G G G CHAF1B TEAD2 25609649 intact exp G G G CDK1 CHAF1B 10938080 hprd,bci exp P P P GP P P GP CHAF1B LRIF1 26496610 biogrid,intact exp GP G P P GP SUMO2 CHAF1B 19394292 biogrid exp P P P GP G P P GP JUN CHAF1B 25609649 intact exp P GP G P P G APP CHAF1B 21832049 biogrid exp P P GP G P GP CBX6 CHAF1B 21282530 biogrid exp P GP G P P GP CHAF1B HIST2H3A, HIST2H3C, HIST2H3D 21724829 biogrid exp, ortho P P P P P P P CBX5 CHAF1B 20850016,12697822,15882967,15306854,20562864,19498464, 25402006, 21836163 biogrid,intact exp, ortho, pred P P P GP G P P GP CHAF1B HIST3H3 20850016,20953179, 25402006, 21836163 biogrid exp, ortho, pred P P P P P P P RBBP4 CHAF1B 9614144, 25402006 hprd,intact,bci exp, ortho, pred P P P GP G P P GP CHAF1B ASF1A 16980972,11897662, 25402006, 21836163 hprd,biogrid,dip,bci exp, ortho, pred G G G CHAF1B SETDB1 19498464, 25402006, 21836163 biogrid exp, pred P P P GP G P P GP FEN1 CHAF1B 25402006, 21836163 bci exp, pred P P P GP G P P GP CHAF1B CBX3 20850016, 25402006, 23023127 biogrid exp, pred P P P GP G P P GP HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J CHAF1B 20080577,22195966,19498464,20504901,19410544,14718166,26527279,25281560,17081972,16622419,19410545,15664198, 25402006 hprd,biogrid,i2d,intact,dip,bci exp, pred P P P P G P P P PCNA CHAF1B 26344197,22939629, 25402006 biogrid exp, pred P P P GP G P P GP CBX1 CHAF1B 21888893, 25402006, 21836163 intact exp, pred P P P GP G P P GP CDK2 CHAF1B 10938080, 25402006 hprd,bci exp, pred P P P GP G P P GP CHAF1B ASF1B 16980972,26527279,11897662,17353931, 25402006, 23023127, 21836163 hprd,biogrid,intact,dip exp, pred G G G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 CHAF1B 21724829, 25402006 biogrid exp, pred P P P P P P P CHAF1A CHAF1B 21724829,26344197,22939629,9614144,19498464, 25402006, 21836163, 16082366 hprd,biogrid,intact,bci exp, pred P P P GP G P P GP PPP5C CHAF1B ortho P P P GP G P P GP YWHAH CHAF1B ortho P P GP G P P GP TAF6 CHAF1B 23023127, 21836163 pred P P P GP G P P GP CHAF1B PIWIL1 21836163 pred P P P G P GP CHAF1B SRCAP 21836163 pred P P GP G P P GP CHAF1B ING2 25402006 pred P P P GP G P P GP CHAF1B SMARCC2 25402006 pred P P P GP G P P GP CHAF1B CENPO 21836163 pred G G G CHAF1B DDB2 23023127 pred P P P GP P P GP HDAC3 CHAF1B 21836163 pred P P P GP G P P GP CHAF1B CENPL 21836163 pred P P P GP G P P GP HIST1H2BD CHAF1B 23023127 pred P P P P P P P CHAF1B PHF20 25402006 pred P P P GP G P P GP SUV39H1 CHAF1B 25402006, 23023127, 21836163 pred G G G CHAF1B NAP1L4 21836163 pred P P GP G P P GP CENPB CHAF1B 21836163 pred P P GP G P P GP HAT1 CHAF1B 21836163 pred P P P GP G P P GP CHAF1B BAZ2A 21836163 pred P G G P GP CHAF1B AGO1 21836163 pred G G G CHAF1B RFWD3 23023127 pred G G TOB1 CHAF1B 25402006 pred P P P GP G P P GP MTA2 CHAF1B 25402006 pred P P P GP P P P CHAF1B HIST2H2AB 21836163 pred P P P P P P P CHAF1B ERCC8 23023127 pred G G G CHAF1B WAPAL 21836163 pred P P P GP G P P GP CHAF1B SETD2 21836163 pred P P GP G P P GP CHAF1B HDAC6 21836163 pred P P P GP G P P GP TADA3 CHAF1B 21836163 pred P P P GP G P P GP PARN CHAF1B 21836163 pred P P P GP G P P GP CHAF1B MBD1 25402006, 21836163 pred P P P GP G P P GP CHAF1B LBR 25402006 pred P P P GP G P P GP CHEK1 CHAF1B 25402006 pred GP SMARCB1 CHAF1B 25402006 pred P P P GP G P P GP RB1 CHAF1B 25402006 pred P P P GP G P P GP CHAF1B WDR82 23023127 pred G G G CHAF1B ACTR6 21836163 pred P P P GP G P P GP TP53BP1 CHAF1B 25402006 pred P P P GP G P P GP CHAF1B HIST2H2BE 21836163 pred P P P GP G P P GP PPP2R1A CHAF1B 23023127 pred P P GP G P P GP CHAF1B SMARCC1 25402006, 21836163 pred P P P GP G P P GP CHAF1B CENPP 21836163 pred P P P P P P CHAF1B TAF12 23023127, 21836163 pred P P P P P P GP UBE2D2 CHAF1B 21836163 pred P P P G G P GP BLM CHAF1B 25402006 pred P P P GP G P P GP CHAF1B DNMT3A 25402006 pred P P P GP G P P GP MYH1 CHAF1B 25402006 pred G CNOT3 CHAF1B 25402006, 21836163 pred P P P GP G P P GP MKI67 CHAF1B 25402006 pred P P P GP G P P GP CHAF1B DDB1 23023127 pred P P P GP G P P GP CHAF1B TAF11 21836163 pred G G G CHAF1B IPO4 25402006 pred P P P GP G P P GP CHAF1B ZNF331 21836163 pred G G G CHAF1B TLK1 25402006 pred P P GP G P P GP CHAF1B CNOT8 21836163 pred P P P GP G P P GP CHAF1B MYO1A 25402006 pred P P GP G P P GP ARPC4 CHAF1B 23023127 pred G G NR4A2 CHAF1B 21836163 pred P P P GP G P P P CHAF1B CENPM 21836163 pred P P P GP P P P SUPT3H CHAF1B 21836163 pred P P P P G P P GP CHAF1B DNMT3B 25402006 pred P P P GP G P P GP HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM CHAF1B 23023127 pred P P P P P P GP CHAF1B EHMT1 21836163 pred G G G MYO1C CHAF1B 25402006 pred P P GP G P P GP CNOT4 CHAF1B 21836163 pred P P P GP G P P GP H3F3A, H3F3B CHAF1B 25402006 pred P P P GP G P P GP CHAF1B SUZ12 25402006 pred P P P GP G P P G SP100 CHAF1B 25402006 pred P P P GP G P P P CHAF1B TLK2 25402006 pred G G G CHAF1B HDAC5 21836163 pred P P P GP G P P GP CHAF1B CDYL 25402006 pred P P P GP G P P GP SMARCA4 CHAF1B 25402006, 21836163 pred P P P GP G P P GP E2F6 CHAF1B 21836163 pred G G CHD3 CHAF1B 23023127, 21836163 pred P P GP G P P GP CHAF1B HIST2H2AC 21836163 pred P P P P P P P CHAF1B UBE2V2 23023127 pred G G G CHAF1B SUV420H1 21836163 pred P P P GP G P P GP AIRE CHAF1B 25402006 pred P P P P P P P BRCA1 CHAF1B 25402006 pred P P P GP P P GP CHAF1B NSL1 21836163 pred P P P GP G P P GP KMT2A CHAF1B 25402006 pred P P P GP G P P GP CHAF1B NCOR2 21836163 pred P P GP G P P GP BTG2 CHAF1B 21836163 pred G G GP CHAF1B NR2E3 25402006 pred CHAF1B MTA1 21836163 pred P P P GP G P P GP SMARCA5 CHAF1B 25402006, 21836163 pred P P P GP G P P GP CHAF1B TTF1 21836163 pred P P P GP G P P GP CHAF1B RCOR1 21836163 pred P P P GP G P P GP GNB1 CHAF1B 23023127 pred P GP G P P GP CHAF1B CENPQ 21836163 pred CHAF1B H3F3C 21836163 pred P P P P P P P CHAF1B CAND1 21836163 pred P GP G P GP CHAF1B WDR77 23023127 pred P P P GP G P P GP PPP2CA CHAF1B 23023127 pred P P P GP G P P GP CHAF1B L3MBTL1 25402006 pred G G G CHAF1B EMSY 21836163 pred P P P GP G P P GP CAND2 CHAF1B 21836163 pred P P GP G P P GP CHD1 CHAF1B 21836163 pred P P GP G P P GP CHAF1B TRIM28 25402006 pred P P P GP G P P GP CHAF1B ING4 25402006 pred P P GP G P P GP CHAF1B CNOT2 21836163 pred G G G BPTF CHAF1B 21836163 pred P GP G P P GP CHAF1B MIS12 25402006 pred P P P GP G P P GP EED CHAF1B 25402006, 21836163 pred P P GP G P P GP CHAF1B APPL1 25402006 pred P P P GP G P P GP HIST1H2BK CHAF1B 23023127 pred P P P GP G P P GP NASP CHAF1B 25402006 pred P P P GP G P P GP CHAF1B CENPT 21836163 pred P P GP G P P GP GNB2 CHAF1B 23023127 pred P GP G P P GP CHAF1B PHF21A 21836163 pred P P GP G P GP CHAF1B PHF8 25402006 pred P P P GP G P P GP CNOT1 CHAF1B 21836163 pred P P GP G P P GP H2AFZ CHAF1B 23023127 pred P P P GP G P P GP CHAF1B SUPT16H 25402006, 21836163 pred P P P GP G P P GP HIRA CHAF1B 25402006, 21836163 pred P P P GP G P P GP CHAF1B SUV39H2 21836163 pred G G P GP CHAF1B PRPF19 23023127 pred P P P GP G P P GP CHAF1B CHD5 23023127 pred P P P P P P GP UBE2C CHAF1B 23023127 pred P P P GP G P P GP CDC7 CHAF1B 25402006 pred P P P GP P P GP CHAF1B ZNF335 21836163 pred G G G CHAF1B HELLS 21836163 pred P P GP P P GP CHAF1B SEH1L 23023127 pred P P GP G P P GP CHAF1B BAZ1A 21836163 pred P P P GP G P P GP CCR4 CHAF1B 21836163 pred P P P P G P P P CHAF1B EZH2 21836163 pred P P P GP P P GP CHAF1B H2BFWT 21836163 pred P P P P P P CHAF1B CENPN 21836163 pred G G HOXA1 CHAF1B 21836163 pred P P P P P P UBE2A CHAF1B 21836163 pred G G G CHAF1B SF3B3 21836163 pred P P P GP G P P GP CHAF1B MYSM1 21836163 pred P P P GP G P P GP CHAF1B EHMT2 21836163, 21836163 pred P GP P P GP GAS7 CHAF1B 23023127 pred P G G GP CHAF1B ATF7IP2 21836163 pred P P P GP G P P GP CHAF1B CHD8 21836163 pred G G G CHAF1B HIST1H2BH 23023127 pred G CHAF1B HDAC9 25402006 pred P P P GP G P P GP CHAF1B TAF4B 21836163 pred P P GP G P P GP CHAF1B FZR1 23023127 pred P GP G P P GP CDK7 CHAF1B 23023127 pred P P P GP G P P GP SMARCA2 CHAF1B 21836163 pred P P P GP G P P GP CHAF1B UBE2E3 21836163 pred P P GP G P P GP CHAF1B ATF7IP 21836163 pred P P P GP G P P GP GNG2 CHAF1B 23023127 pred P P G G P GP CHAF1B BANP 21836163 pred P P GP G P P GP HIST1H2BJ CHAF1B 23023127 pred P P P P P P P SAP30 CHAF1B 25402006 pred P P GP G P P GP CHAF1B CHRAC1 21836163 pred G G G ARPC5 CHAF1B 23023127 pred P P GP G P P GP CHAF1B INCENP 25402006 pred P P P P P P GP CHAF1B HDAC1 25402006 pred P P P GP G P P GP CHAF1B RBBP7 25402006, 21836163 pred P P P GP G P P GP VDR CHAF1B 25402006 pred G G G NAP1L1 CHAF1B 21836163 pred P P P GP G P P GP CHAF1B BAZ1B 23023127, 21836163 pred P P P GP G P P GP CHEK2 CHAF1B 25402006, 21836163 pred P P GP P P GP SMARCA1 CHAF1B 21836163 pred P GP G P P GP CENPA CHAF1B 25402006 pred P P P GP G P P GP CHAF1B HDAC2 25402006 pred P P P GP G P P GP CHAF1B ARPC1A 23023127 pred P P P GP G P P GP CHAF1B UBE2S 23023127 pred P P G G GP CHAF1B CNOT6 21836163 pred P GP G P P G HCFC1 CHAF1B 25402006 pred P G G P GP

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q13112 - 15664198 - C 5 Q13112 P68431 - 15664198 - X 2 B2R4R0 Q13112 affinity chromatography technology 21724829 physical association X 2 B2R4R0 Q13112 affinity chromatography technology 21724829 physical association X 2 A4D177 Q13112 affinity chromatography technology 20850016 physical association X 2 Q13112 Q13111 affinity chromatography technology 21724829 physical association X 2 Q13112 P05067-7 pull down 21832049 direct interaction X 2 Q13112 Q13111 biochemical 22939629 colocalization X 2 Q13112 Q13111 affinity chromatography technology 9614144 physical association X 2 Q13112 affinity chromatography technology 19498464 physical association X 2 Q13112 P61956-2 affinity chromatography technology 19394292 physical association X 2 O95503 Q13112 affinity chromatography technology 21282530 physical association X 2 A0A024R5H0 Q13112 affinity chromatography technology 19759913 physical association X 2 P12004 Q13112 biochemical 22939629 colocalization X 2 Q71DI3 Q13112 affinity chromatography technology 21724829 physical association X 2 Q9UIG0 Q13112 affinity chromatography technology 12837248 physical association X 2 Q9UIG0 Q13112 affinity chromatography technology 12837248 physical association X 2 Q13112 affinity chromatography technology 22190034 physical association X 2 Q13112 P68431 affinity chromatography technology 16622419 physical association X 2 Q13112 P68431 affinity chromatography technology 15664198 physical association X 2 Q13112 P68431 affinity chromatography technology 15664198 physical association X 2 Q13112 P45973 affinity chromatography technology 20562864 physical association X 2 Q13112 P48431 affinity chromatography technology 23667531 physical association X 2 Q13112 Q16695 unspecified method 20850016 direct interaction X 2 Q13112 P45973 affinity chromatography technology 20850016 physical association X 2 Q13112 affinity chromatography technology 24711643 physical association X 2 Q13112 Q9H0W5 affinity chromatography technology 24711643 physical association X 2 Q13112 A0A024R7G4 affinity chromatography technology 17353931 physical association X 2 Q13112 P45973 two hybrid 12697822 direct interaction X 2 Q13112 Q9Y294 pull down 11897662 direct interaction X 2 Q13112 A0A024R7G4 pull down 11897662 direct interaction X 2 Q13112 Q9Y294 affinity chromatography technology 11897662 physical association X 2 Q13112 A0A024R7G4 affinity chromatography technology 11897662 physical association X 2 Q13112 Q9Y294 pull down 16980972 direct interaction X 2 Q13112 Q9Y294 affinity chromatography technology 16980972 physical association X 2 Q13112 A0A024R7G4 affinity chromatography technology 16980972 physical association X 2 Q13112 P45973 unspecified method 15882967 direct interaction X 2 Q13112 P45973 unspecified method 15882967 direct interaction X 2 Q13112 P45973 affinity chromatography technology 15882967 physical association X 2 Q13112 P45973 affinity chromatography technology 15882967 physical association X 2 Q13112 Q16695 affinity chromatography technology 20953179 physical association X 2 Q13112 P68431 affinity chromatography technology 14718166 physical association X 2 Q13112 P45973 affinity chromatography technology 15306854 physical association X 2 Q13112 P45973 affinity chromatography technology 15306854 physical association X 2 Q13112 P45973 biochemical 15306854 colocalization X 2 Q13112 P68431 affinity chromatography technology 20504901 physical association X 2 Q13112 P68431 affinity chromatography technology 20504901 physical association X 2 Q13112 P68431 affinity chromatography technology 17081972 physical association X 2 Q13112 P68431 imaging technique 17081972 colocalization X 2 Q13112 P68431 affinity chromatography technology 19410544 physical association X 2 Q13112 P68431 affinity chromatography technology 22195966 physical association X 2 P0CG48 Q13112 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q13112 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q13112 affinity chromatography technology 24816145 physical association X 2 P0CG48 Q13112 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q13112 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q13112 affinity chromatography technology 21906983 physical association X 2 Q96LI5 Q13112 affinity chromatography technology 17452450 physical association X 2 Q13112 coimmunoprecipitation 15664198 association C 6 Q13112 molecular sieving 15664198 association C 7 Q13112 anti bait coimmunoprecipitation 7600578 association C 3 Q13112 molecular sieving 7600578 association C 3 Q13112 cosedimentation through density gradient 8858152 association C 3 Q13112 coimmunoprecipitation 14718166 association C 10 Q13112 tandem affinity purification 20080577 - C 11 Q13112 Q9Y294 anti tag coimmunoprecipitation 16980972 direct interaction X 2 Q13112 Q9Y294 pull down 16980972 direct interaction X 2 Q13112 A0A024R7G4 pull down 16980972 direct interaction X 2 Q13112 P68431 tandem affinity purification 20080577 physical association X 2 A0A024QZJ8 Q13112 in vitro 10938080 - X 2 A0A024QZJ8 Q13112 in vitro 10938080 - X 2 Q13112 A0A024RB10 in vitro 10938080 - X 2 Q13112 A0A024RB10 in vitro 10938080 - X 2 Q13112 Q09028-4 in vivo 9614144 - X 2 Q13112 Q09028-4 in vivo 9614144 - X 2 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 8858152,9614144 - C 3 Q13112 in vivo 9614144 - X 2 Q13112 in vivo 9614144 - X 2 Q13112 P68431 in vivo 15664198,17081972 - X 2 Q13112 P68431 in vitro 15664198,17081972 - X 2 Q13112 Q9Y294 in vivo 11897662 - X 2 Q13112 A0A024R7G4 in vivo 11897662 - X 2 Q13112 P68431 in vivo 15664198,17081972 - X 2 Q13112 P68431 in vitro 15664198,17081972 - X 2 Q13112 Q9Y294 in vivo 11897662 - X 2 Q13112 A0A024R7G4 in vivo 11897662 - X 2 Q13112 tandem affinity purification 21888893 association C 40 Q13112 anti tag coimmunoprecipitation 19410545 association C 4 Q13112 cosedimentation through density gradient 19498464 colocalization C 5 Q13112 tandem affinity purification 19410544 association C 13 Q13112 anti tag coimmunoprecipitation 20562864 association C 84 Q13112 anti tag coimmunoprecipitation 22190034 association C 47 Q13112 pull down 22190034 association C 51 Q13112 Q13111 confocal microscopy 9614144 colocalization X 2 Q13112 anti tag coimmunoprecipitation 17081972 association C 3 Q13112 anti tag coimmunoprecipitation 19498464 association C 3 Q13112 anti bait coimmunoprecipitation 9614144 association C 3 Q13112 anti tag coimmunoprecipitation 19498464 association C 11 Q13112 anti tag coimmunoprecipitation 19498464 association C 13 Q13112 anti tag coimmunoprecipitation 22190034 association C 41 Q13112 anti tag coimmunoprecipitation 19498464 association C 8 Q13112 anti tag coimmunoprecipitation 19498464 association C 5 Q13112 A0A024R7G4 anti bait coimmunoprecipitation 17353931 physical association X 2 Q96LI5 Q13112 anti tag coimmunoprecipitation 17452450 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CBX6 CHAF1B MI:0004(affinity chromatography technology) 21282530 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_262959 bait prey CDK1 CHAF1B MI:0492(in vitro) 10938080 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_16515 - - BANF1 CHAF1B MI:0004(affinity chromatography technology) 19759913 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_127665 bait prey CHAF1B ASF1B MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0493(in vivo)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation) 11897662,16980972,17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(intact) BIOGRID_111407|DIP_53645|BIOGRID_82079|BIOGRID_129156|HPRD_8732|BIOGRID_111403|UniProt_149406 prey|-|prey|bait|-|bait|prey bait|-|bait|prey|-|prey|bait CHAF1B SETDB1 MI:0004(affinity chromatography technology) 19498464 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_129538 bait prey HIST1H3A CHAF1B MI:0007(anti tag coimmunoprecipitation)|MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,14718166,15664198,16622419,17081972,19410544,19410545,19498464,20504901,22195966 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0403(colocalization)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_99616|UniProt_99118|BIOGRID_147296|BIOGRID_147297|HPRD_35375|BIOGRID_244220|BIOGRID_244492|BIOGRID_140588|BIOGRID_136935|BIOGRID_140617|BIOGRID_166124|BIOGRID_244485|BIOGRID_149418|UniProt_101942|MINT_71974|MINT_41990|UniProt_101945|MINT_71980|MINT_41996|UniProt_87423 bait|bait|bait|prey|-|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|bait|-|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey|prey|prey CHAF1B BAZ1B MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12837248 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_88874|BIOGRID_88870 prey|prey bait|bait CHAF1B HIST3H3 MI:0401(biochemical) 20953179 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_133863 prey bait SOX2 CHAF1B MI:0004(affinity chromatography technology) 23667531 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_275002 bait prey APP CHAF1B MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229631 prey bait SUMO2 CHAF1B MI:0004(affinity chromatography technology) 19394292 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_130934 bait prey CHAF1B HIST2H3A; MI:0415(enzymatic study) 21724829 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_194715 bait prey CHAF1A CHAF1B MI:0401(biochemical)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0663(confocal microscopy)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0663(confocal microscopy)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,19498464,21724829,22939629,8858152,9614144 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|-|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact) BIOGRID_230277|HPRD_8728|BIOGRID_100952|BIOGRID_194714|UniProt_134403|UniProt_101948|MINT_71984|MINT_42000|HPRD_40567|UniProt_134404|MINT_41995|MINT_71979|UniProt_101944 bait|-|prey|prey|neutral component|neutral component|neutral component|neutral component|-|prey|bait|bait|bait prey|-|bait|bait|neutral component|neutral component|neutral component|neutral component|-|bait|prey|prey|prey PCNA CHAF1B MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238269 prey bait CHAF1B CNOT6L MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17452450 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_89312|BIOGRID_256374 prey|prey bait|bait UBC CHAF1B MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,21963094,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_174064|BIOGRID_177643|BIOGRID_168250|BIOGRID_265191|BIOGRID_268977 bait|bait|bait|bait|bait prey|prey|prey|prey|prey CDK2 CHAF1B MI:0492(in vitro) 10938080 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_18118 - - CHAF1B ASF1A MI:0096(pull down)|MI:0114(x-ray crystallography)|MI:0493(in vivo)|MI:0096(pull down)|MI:0114(x-ray crystallography)|MI:0096(pull down) 11897662,16980972 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|MI:0465(dip)|(biogrid)|(biogrid) BIOGRID_111405|BIOGRID_129152|HPRD_8731|DIP_53643|BIOGRID_129153|BIOGRID_111402 prey|bait|-|-|bait|bait bait|prey|-|-|prey|prey HIST1H4A CHAF1B MI:0415(enzymatic study)|MI:0415(enzymatic study) 21724829 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_194716|BIOGRID_194713 prey|bait bait|prey RBBP4 CHAF1B MI:0493(in vivo)|MI:0493(in vivo)|MI:0663(confocal microscopy) 8858152,9614144 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association) MI:0468(hprd)|MI:0468(hprd)|(intact) HPRD_8730|HPRD_40567|UniProt_134404 -|-|prey -|-|bait CBX5 CHAF1B MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0686(unspecified method)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0686(unspecified method)|MI:0686(unspecified method)|MI:0686(unspecified method)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,12697822,15306854,15882967,19498464,20562864 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint) UniProt_106254|UniProt_101948|MINT_71984|MINT_42000|BIOGRID_138781|BIOGRID_133159|BIOGRID_138776|BIOGRID_138785|BIOGRID_133166|BIOGRID_133173|BIOGRID_133153|BIOGRID_89611|BIOGRID_246552|MINT_41988|MINT_71972|UniProt_101941|MINT_41994|UniProt_101943|MINT_71978 bait|neutral component|neutral component|neutral component|bait|bait|bait|bait|bait|bait|prey|prey|bait|bait|bait|bait|bait|bait|bait prey|neutral component|neutral component|neutral component|prey|prey|prey|prey|prey|prey|bait|bait|prey|prey|prey|prey|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality JUN CHAF1B 25609649 0006 HT PCNA CHAF1B 26344197,22939629 0401,0401 HT RPL10 CHAF1B 26496610,26496610 0007,0004 HT CBX5 CHAF1B 19498464,20562864,15306854,15306854,15882967 0007,0007,0004,0401,0004 LC INSL3 CHAF1B 26186194 0004 HT HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J CHAF1B 19410545,16622419,17081972,26527279,15664198,19498464,20504901,17081972,15664198,19410544,22195966,25281560,15664198,19410544,14718166,17081972,20080577,26527279 0007,0004,0007,0004,0004,0007,0004,0428,0019,0676,0004,1313,0071,0004,0004,0004,0676,0401 LC RBPJ CHAF1B 25609649,25609649 0676,0004 HT CHAF1A CHAF1B 26344197,9614144,19498464,19498464,9614144,21724829,9614144,22939629 0401,0006,0007,0029,0004,0004,0663,0401 HT,LC CHAF1B SMAD4 25609649,25609649 0676,0004 HT CHAF1B TEAD2 25609649,25609649 0676,0004 HT CHAF1B LRIF1 26496610,26496610 0007,0004 HT CHAF1B ASF1B 16980972,11897662,11897662,16980972,17353931,26527279,17353931 0096,0096,0004,0004,0006,0004,0004 LC,HT CHAF1B ASF1A 16980972,11897662,16980972,11897662,16980972 0096,0096,0007,0004,0004 LC CHAF1B HEL25 20850016,20562864,15306854,15306854,15882967 0004,0004,0004,0401,0004 LC JUN CHAF1B 25609649 0006 HT PCNA CHAF1B 26344197,22939629 0401,0401 HT RPL10 CHAF1B 26496610,26496610 0007,0004 HT INSL3 CHAF1B 26186194 0004 HT RBPJ CHAF1B 25609649,25609649 0676,0004 HT CHAF1A CHAF1B 26344197,22939629 0401,0401 HT CHAF1B SMAD4 25609649,25609649 0676,0004 HT CHAF1B TEAD2 25609649,25609649 0676,0004 HT CHAF1B LRIF1 26496610,26496610 0007,0004 HT CHAF1B ASF1B 17353931,17353931 0006,0004 HT CBX5 CHAF1B 19498464,20562864,15306854,15306854,15882967 0007,0007,0004,0401,0004 LC HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J CHAF1B 19410545,16622419,17081972,26527279,15664198,19498464,20504901,17081972,15664198,19410544,22195966,25281560,15664198,19410544,14718166,17081972,20080577,26527279 0007,0004,0007,0004,0004,0007,0004,0428,0019,0676,0004,1313,0071,0004,0004,0004,0676,0401 LC CHAF1A CHAF1B 9614144,19498464,19498464,9614144,21724829,9614144 0006,0007,0029,0004,0004,0663 LC CHAF1B ASF1B 16980972,11897662,11897662,16980972,26527279 0096,0096,0004,0004,0004 LC CHAF1B ASF1A 16980972,11897662,16980972,11897662,16980972 0096,0096,0007,0004,0004 LC CHAF1B HEL25 20850016,20562864,15306854,15306854,15882967 0004,0004,0004,0401,0004 LC PCNA CHAF1B 26344197,22939629 0401,0401 LC CBX5 CHAF1B 12697822,15306854,15306854 0018,0004,0401 LC HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J CHAF1B 26527279,15664198,15664198,15664198,26527279 0004,0004,0019,0071,0401 LC CHAF1A CHAF1B 26344197,19498464,19498464,22939629 0401,0007,0029,0401 LC CHAF1B HEL25 12697822,15306854,15306854 0018,0004,0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q13112 O75531 CHAF1B BANF1 0.126 19759913 Q13112 P01106 CHAF1B MYC 0.126 21150319 Q13112 O95503 CHAF1B CBX6 0.126 21282530 Q13112 P04578 CHAF1B ENV 0.286 22190034 Q13112 P05412 CHAF1B JUN 0.126 25609649 Q9QWF0 Q13112 CHAF1A CHAF1B 0.236 26496610 Q9R190 Q13112 MTA2 CHAF1B 0.236 26496610 Q16695 Q13112 HIST3H3 CHAF1B 0.354 20850016,20953179 Q13485 Q13112 SMAD4 CHAF1B 0.236 25609649 Q15562 Q13112 TEAD2 CHAF1B 0.236 25609649 Q9D8B3 Q13112 CHMP4B CHAF1B 0.236 26496610 Q13112 Q06330 CHAF1B RBPJ 0.236 25609649 Q13112 P83916 CHAF1B CBX1 0.236 21888893,27705803 Q13112 P83917 CHAF1B CBX1 0.236 26496610 Q13112 P27635 CHAF1B RPL10 0.236 26496610 Q5T3J3 Q13112 LRIF1 CHAF1B 0.236 26496610 Q13112 P35550 CHAF1B FBL 0.236 26496610 Q13112 P45973 CHAF1B CBX5 0.917 19498464,27705803,15882967,20562864,15306854,12697822,20850016 Q9Y294 Q13112 ASF1A CHAF1B 0.837 16980972,11897662 Q9NVP2 Q13112 ASF1B CHAF1B 0.848 27705803,17353931,16980972,11897662,26527279 Q13112 Q13111 CHAF1B CHAF1A 0.78 19498464,27705803,21724829,26344197,9614144,22939629 Q96LI5 Q13112 CNOT6L CHAF1B 0.21 17452450 Q9UKB1 Q13112 FBXW11 CHAF1B 0.126 25515538 Q13112 P62805 CHAF1B HIST4H4 0.376 21724829 Q13112 A3KMF4 CHAF1B A3KMF4 0.126 26496610 Q13112 P48431 CHAF1B SOX2 0.126 23667531 Q9Y266 Q13112 NUDC CHAF1B 0.126 27705803 Q9UHV9 Q13112 PFDN2 CHAF1B 0.126 27705803 Q9NQP4 Q13112 PFDN4 CHAF1B 0.126 27705803 Q71DI3 Q13112 HIST2H3D CHAF1B 0.21 21724829 Q15047 Q13112 SETDB1 CHAF1B 0.21 19498464 Q13112 P12004 CHAF1B PCNA 0.155 26344197,22939629 Q13112 P05067 CHAF1B APP 0.183 21832049 Q13112 P84243 CHAF1B H3F3B 0.126 27705803 Q13112 P68431 CHAF1B HIST1H3J 0.946 19498464,22195966,19410544,25281560,19410545,26527279,15664198,14718166,20504901,17081972 Q13263 Q13112 TRIM28 CHAF1B 0.126 27705803 Q13112 Q04637 CHAF1B EIF4G1 0.126 27705803 Q13185 Q13112 CBX3 CHAF1B 0.332 20850016,27705803 Q13112 P51460 CHAF1B INSL3 0.126 26186194 Q13469 Q13112 NFATC2 CHAF1B 0.126 27637333 Q13112 Q09028 CHAF1B RBBP4 0.396 27705803,9614144

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HAT1 CHAF1B MI:0362 inference MI:0461 interaction database XPO1 CHAF1B MI:0362 inference MI:0461 interaction database OBSL1 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database BANF1 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database MTA2 CHAF1B MI:0362 inference MI:0461 interaction database LUC7L3 CHAF1B MI:0362 inference MI:0461 interaction database CBX6 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database HSPA4L CHAF1B MI:0362 inference MI:0461 interaction database MYC CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database ALDOA CHAF1B MI:0362 inference MI:0461 interaction database ALDOB CHAF1B MI:0362 inference MI:0461 interaction database APP CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database JUN CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database NPM1 CHAF1B MI:0362 inference MI:0461 interaction database PARP1 CHAF1B MI:0362 inference MI:0461 interaction database UBC CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database HSPA1B CHAF1B MI:0362 inference MI:0461 interaction database HSPA8 CHAF1B MI:0362 inference MI:0461 interaction database PCNA CHAF1B MI:0362 inference MI:0461 interaction database XRCC6 CHAF1B MI:0362 inference MI:0461 interaction database XRCC5 CHAF1B MI:0362 inference MI:0461 interaction database HSPA6 CHAF1B MI:0362 inference MI:0461 interaction database FBL CHAF1B MI:0362 inference MI:0461 interaction database ATP6V0C CHAF1B MI:0362 inference MI:0461 interaction database RPL10 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database PRDX2 CHAF1B MI:0362 inference MI:0461 interaction database HSPA1L CHAF1B MI:0362 inference MI:0461 interaction database HSPA4 CHAF1B MI:0362 inference MI:0461 interaction database FEN1 CHAF1B MI:0362 inference MI:0461 interaction database CBX5 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database SOX2 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database NASP CHAF1B MI:0362 inference MI:0461 interaction database CENPA CHAF1B MI:0362 inference MI:0461 interaction database MCM2 CHAF1B MI:0362 inference MI:0461 interaction database INSL3 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database AFF1 CHAF1B MI:0362 inference MI:0461 interaction database HMGA2 CHAF1B MI:0362 inference MI:0461 interaction database PPP5C CHAF1B MI:0362 inference MI:0461 interaction database HIRA CHAF1B MI:0362 inference MI:0461 interaction database HSPA2 CHAF1B MI:0362 inference MI:0461 interaction database SUMO2 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database YWHAG CHAF1B MI:0362 inference MI:0461 interaction database CNBP CHAF1B MI:0362 inference MI:0461 interaction database HIST1H4A CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database PRKDC CHAF1B MI:0362 inference MI:0461 interaction database CBX1 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database H3F3A CHAF1B MI:0362 inference MI:0461 interaction database YWHAH CHAF1B MI:0362 inference MI:0461 interaction database RBPJ CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database RBBP4 CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database CHAF1A CHAF1B MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B PRDX4 MI:0362 inference MI:0461 interaction database CHAF1B CBX3 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B MTA1 MI:0362 inference MI:0461 interaction database CHAF1B SMAD4 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B HDAC1 MI:0362 inference MI:0461 interaction database CHAF1B SETDB1 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B TEAD2 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B EZH2 MI:0362 inference MI:0461 interaction database CHAF1B RBBP7 MI:0362 inference MI:0461 interaction database CHAF1B HIST3H3 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B LRIF1 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B H3F3C MI:0362 inference MI:0461 interaction database CHAF1B HIST2H3A MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B HJURP MI:0362 inference MI:0461 interaction database CHAF1B ZCCHC13 MI:0362 inference MI:0461 interaction database CHAF1B HSPH1 MI:0362 inference MI:0461 interaction database CHAF1B CNOT6L MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B SIN3A MI:0362 inference MI:0461 interaction database CHAF1B HIST1H4G MI:0362 inference MI:0461 interaction database CHAF1B CCDC8 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B CHMP4B MI:0362 inference MI:0461 interaction database CHAF1B LUC7L MI:0362 inference MI:0461 interaction database CHAF1B ASF1B MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B BAZ1B MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B ASF1A MI:0045 experimental interaction detection MI:0461 interaction database CHAF1B LOXL2 MI:0045 experimental interaction detection MI:0461 interaction database