PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RBPJ NACC1 25609649 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NACC1 MAP3K5 25852190 biogrid,intact exp G GP G G GP GP G G GP G GP G GP G G G GP GP GP G G GP G G G GP GP GP G KLHL2 NACC1 19121354 biogrid exp G G G G G G G G G G GP GP G G G GP G G G G G GP G G GP G G GP G PARK2 NACC1 24231739 biogrid exp P GP G P GP G GP GP G GP P P G P GP GP P G P GP G GP P GP G NACC1 AXIN2 19888210 i2d exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G NACC1 FOXA2 25609649 intact exp P GP G GP GP GP P GP GP G BCOR NACC1 19121354 biogrid exp G G G G G G G G G G G G G G G G G G G G G G CSNK1A1 NACC1 19888210 i2d exp G G G G G G G G G G G G G G G G G G GP G G G G G G G G G G AXIN1 NACC1 19888210 i2d exp GP GP G GP GP G P GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G DVL1 NACC1 19888210 i2d exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ZBTB6 NACC1 19121354 biogrid exp P P P P P P P P P P P P P CSNK1E NACC1 19888210 i2d exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G CUL4A NACC1 17699672 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NACC1 NACC1 19407373,17130457 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G KPNA4 NACC1 22665369 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ENC1 NACC1 19121354 biogrid exp GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP GP GP GP G STRN3 NACC1 24255178 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G CUL3 NACC1 17699672 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G MRPL43 NACC1 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G XPO1 NACC1 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP GP GP GP G HDAC3 NACC1 16033423 hprd,biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP GP GP GP G PSMD7 NACC1 17699672 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G FOXA1 NACC1 25609649 intact exp GP G G G GP G GP G GP GP G NACC1 FOXJ2 25609649 intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP GP GP GP G SNW1 NACC1 20467437 intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ITLN1 NACC1 26186194 biogrid exp G G G G GP GP G G G GP G G GP G GP G G GP G NACC1 CDC5L 20467437 intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G TARDBP NACC1 23022214 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G NACC1 FOXP3 25609649 intact exp, ortho G G G P G G G P P KPNA3 NACC1 22665369 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ZBTB14 NACC1 19121354, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP P G GP GP GP G GP G GP P BCL6 NACC1 19121354, 23023127 biogrid exp, pred G G G G GP G G G G G G G G G G G G G G G GP G G G G GP G G G HDAC4 NACC1 16033423, 21836163 hprd,biogrid exp, pred GP G G G GP GP G G GP G GP GP GP G G GP GP GP GP G P GP GP G GP GP GP GP G SUMO3 NACC1 ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G L3MBTL2 NACC1 ortho GP G G G G GP G GP G G G G G G G GP GP G G G G GP G G GP G G G G SOX2 NACC1 ortho P P G P GP G P GP G P P GP GP GP P G P GP P GP P GP GP G NEB NACC1 ortho G P G G G G P G G G G G G G P G NACC1 ZNF281 ortho G G G G G GP G G GP G GP GP G G G GP GP G GP G G G G G GP G GP GP G NACC1 NANOG 25402006 ortho, pred P P G P G P G GP NACC1 WDR18 25402006 ortho, pred GP P G P P P GP GP GP P P P P GP P G GP P GP GATAD2B NACC1 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP P G P GP GP G GP GP GP GP G SMARCC1 NACC1 25402006 ortho, pred GP G G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP G G GP GP GP GP G NACC1 SALL4 25402006 ortho, pred P P G GP POU5F1 NACC1 25402006 ortho, pred P P P P P P P P P P P P P P P P P P P P NACC2 NACC1 25402006, 23023127 ortho, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G NACC1 SALL1 25402006 ortho, pred P P G P GP G P GP G GP GP P P GP GP P G P P P P P GP P G NACC1 MYBBP1A 25402006 ortho, pred GP GP G G GP GP G G GP G GP G G G G GP GP G GP G GP GP GP G GP GP GP GP G NACC1 ARID3A 25402006 ortho, pred GP G G G GP GP G G G G GP G GP G G GP GP G GP G GP GP G G GP GP GP GP G ZFP42 NACC1 25402006 ortho, pred P P P P P P P P P P P P P P P P ARID3B NACC1 25402006 ortho, pred P P P P P P P P P P GP P P P P P GP SOCS3 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP G GP G GP GP G ZBTB5 NACC1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G NACC1 KLHL11 23023127 pred P P P P P P P P P P P P P P P P GP SOCS2 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G NACC1 BTBD7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G KLHL40 NACC1 23023127 pred G G KLHL23 NACC1 23023127 pred G G G G G P P G G G GP P GP G G G KBTBD3 NACC1 23023127 pred G GP G G G G G P G G G G G G G G G G G G G G G G G TCEB2 NACC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VHL NACC1 23023127 pred G G G G G G G G G G GP GP GP G G G G G P G G GP GP G G G G GP G RIF1 NACC1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G P GP GP GP G GP GP GP G GP GP GP GP G KLHL34 NACC1 23023127 pred P P P GP GP P P P P GP GP P P P P P G GP P P P NACC1 KLHL20 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ZBTB7A NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G ZBTB2 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP GP GP GP G ZBTB45 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G POU5F1B NACC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G NACC1 KBTBD4 23023127 pred GP GP GP G P G GP P P G GP GP G GP G P GP GP G GP G P GP KLHL17 NACC1 23023127 pred P G G G G G GP G P GP GP G G GP G G G G G GP G GP GP G BACH1 NACC1 23023127 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP GP G GP GP GP GP G NACC1 KLHL25 23023127 pred GP GP G G G GP G P GP G GP GP GP G G GP GP G GP G P GP GP G GP GP GP GP G ZBTB16 NACC1 23023127 pred G GP G G G GP G G GP G G G GP G G GP GP G GP G G GP GP G GP G G GP G KLHL24 NACC1 23023127 pred G G G G G GP G G G G G G G G G GP GP G GP G G G G G GP G G G G GADD45GIP1 NACC1 21836163 pred GP GP G GP G GP GP G GP GP G G GP GP GP GP G P GP GP G GP GP GP GP G NACC1 ZBTB21 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP G G GP G GP GP G KLHL38 NACC1 23023127 pred P P P P P P P P P P P P P P P P P P P HIC2 NACC1 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G NACC1 KLHL28 23023127 pred G G G G G G G G G G GP GP G G G G G G GP G GP G G G G G G G G NACC1 ZBTB18 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NBR1 NACC1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G ZBTB25 NACC1 23023127 pred GP G G P G P P G P P G G GP G P G P GP G BTBD17 NACC1 23023127 pred P P P P P P NACC1 ZBTB32 23023127 pred P P P P P P P P GP ZBTB7C NACC1 23023127 pred G GP G G P P P G G GP G G G GP GP TNFAIP1 NACC1 23023127 pred G G G G G G G G GP G GP G G G G GP G G GP G G G GP G GP G GP G G

PPI - HINT Gene A Gene B PMID Method Quality FOXA1 NACC1 25609649,25609649 0676,0004 HT RBPJ NACC1 25609649,25609649 0676,0004 HT STRN3 NACC1 24255178,24255178 1313,1314 HT MRPL43 NACC1 26186194 0004 HT ITLN1 NACC1 26186194 0004 HT NACC1 NACC1 17130457 0004 LC NACC1 MAP3K5 25852190,25852190 0004,0007 HT NACC1 FOXP3 25609649,25609649 0676,0004 HT NACC1 FOXJ2 25609649,25609649 0676,0004 HT NACC1 FOXA2 25609649,25609649 0676,0004 HT FOXA1 NACC1 25609649,25609649 0676,0004 HT RBPJ NACC1 25609649,25609649 0676,0004 HT STRN3 NACC1 24255178,24255178 1313,1314 HT MRPL43 NACC1 26186194 0004 HT ITLN1 NACC1 26186194 0004 HT NACC1 MAP3K5 25852190,25852190 0004,0007 HT NACC1 FOXP3 25609649,25609649 0676,0004 HT NACC1 FOXJ2 25609649,25609649 0676,0004 HT NACC1 FOXA2 25609649,25609649 0676,0004 HT NACC1 NACC1 17130457 0004 LC ENC1 NACC1 19121354,19121354 0018,0004 LC HDAC3 NACC1 16033423,16033423,16033423 0018,0096,0004 LC ZBTB14 NACC1 19121354,19121354 0018,0004 LC KLHL2 NACC1 19121354,19121354 0018,0004 LC BCL6 NACC1 19121354,19121354 0018,0004 LC HDAC4 NACC1 16033423,16033423,16033423 0018,0096,0004 LC UBE2I NACC1 25891951,25891951 0415,0004 LC ZBTB6 NACC1 19121354,19121354 0018,0004 LC BCOR NACC1 19121354,19121354 0018,0004 LC NACC1 NACC1 19407373 0114 LC NACC1 SENP2 25891951 0415 LC NACC1 SENP1 25891951 0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96RE7 Q8N983 NACC1 MRPL43 0.126 26186194 Q9HC62 Q96RE7 SENP2 NACC1 0.309 25891951 Q96RE7 Q6P5F9 NACC1 XPO1 0.126 26673895 Q9P0K8 Q96RE7 FOXJ2 NACC1 0.236 25609649 Q9Y261 Q96RE7 FOXA2 NACC1 0.236 25609649 Q96RE7 O00214 NACC1 LGALS8 0.236 unassigned1304 Q96RE7 O14682 NACC1 ENC1 0.454 19121354 Q96RE7 O15379 NACC1 HDAC3 0.74 16033423 Q96RE7 O43395 NACC1 PRPF3 0.236 unassigned1304 Q96RE7 O43829 NACC1 ZBTB14 0.454 19121354 Q96RE7 O95198 NACC1 KLHL2 0.454 19121354 Q96RE7 P41182 NACC1 BCL6 0.454 19121354 Q96RE7 P41743 NACC1 PRKCI 0.236 unassigned1304 Q96RE7 P56524 NACC1 HDAC4 0.74 16033423 Q96RE7 P62310 NACC1 LSM3 0.236 unassigned1304 Q96RE7 P62875 NACC1 POLR2L 0.236 unassigned1304 Q96RE7 Q08426 NACC1 EHHADH 0.236 unassigned1304 Q96RE7 Q14241 NACC1 TCEB3 0.236 unassigned1304 Q96RE7 Q15916 NACC1 ZBTB6 0.454 19121354 Q96RE7 Q6W2J9 NACC1 BCOR 0.454 19121354 Q96RE7 Q96KM6 NACC1 ZNF512B 0.236 unassigned1304 Q96RE7 Q96RE7 NACC1 NACC1 0.49 17130457,19407373 Q99633 Q96RE7 PRPF18 NACC1 0.236 unassigned1304 Q9H7E9 Q96RE7 C8ORF33 NACC1 0.236 unassigned1304 Q99683 Q96RE7 MAP3K5 NACC1 0.236 25852190 Q9BZS1 Q96RE7 FOXP3 NACC1 0.236 25609649 Q96RE7 Q06330 NACC1 RBPJ 0.236 25609649 Q96RE7 Q13033 NACC1 STRN3 0.196 24255178 Q96RE7 P55317 NACC1 FOXA1 0.236 25609649 Q96RE7 P63279 NACC1 UBE2I 0.454 25891951 Q96RE7 P29590 NACC1 PML 0.309 25891951 Q96RE7 Q8WWA0 NACC1 ITLN1 0.126 26186194 Q96RE7 Q13148 NACC1 TARDBP 0.523 23022214 Q96RE7 P51665 NACC1 PSMD7 0.21 17699672 Q96RE7 O60260 NACC1 PARK2 0.376 24231739 Q96RE7 Q13619 NACC1 CUL4A 0.21 17699672 Q96RE7 Q13618 NACC1 CUL3 0.376 17699672 Q99459 Q96RE7 CDC5L NACC1 0.126 20467437 Q9P0U3 Q96RE7 SENP1 NACC1 0.309 25891951 Q96RE7 Q13573 NACC1 SNW1 0.126 20467437 Q96RE7 O00505 NACC1 KPNA3 0.21 22665369 Q96RE7 O00629 NACC1 KPNA4 0.21 22665369

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 KPNA3 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database KPNA4 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database ENC1 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database XPO1 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database HDAC3 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB14 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database PARK2 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL2 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database UBC NACC1 MI:0045 experimental interaction detection MI:0461 interaction database PML NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SREBF1 NACC1 MI:0362 inference MI:0461 interaction database BCL6 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SOX2 NACC1 MI:0362 inference MI:0461 interaction database PSMD7 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database HMGA2 NACC1 MI:0362 inference MI:0461 interaction database FOXA1 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database HDAC4 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO2 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO1 NACC1 MI:0362 inference MI:0461 interaction database UBE2I NACC1 MI:0045 experimental interaction detection MI:0461 interaction database POU5F1 NACC1 MI:0362 inference MI:0461 interaction database RBPJ NACC1 MI:0045 experimental interaction detection MI:0461 interaction database POU5F1B NACC1 MI:0362 inference MI:0461 interaction database STRN3 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database TARDBP NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SNW1 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A NACC1 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB6 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database RIF1 NACC1 MI:0362 inference MI:0461 interaction database SUMO4 NACC1 MI:0362 inference MI:0461 interaction database BCOR NACC1 MI:0045 experimental interaction detection MI:0461 interaction database ARID3B NACC1 MI:0362 inference MI:0461 interaction database MRPL43 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database SMARCC2 NACC1 MI:0362 inference MI:0461 interaction database ITLN1 NACC1 MI:0045 experimental interaction detection MI:0461 interaction database GATAD2B NACC1 MI:0362 inference MI:0461 interaction database SMARCC1 NACC1 MI:0362 inference MI:0461 interaction database L3MBTL2 NACC1 MI:0362 inference MI:0461 interaction database NACC2 NACC1 MI:0362 inference MI:0461 interaction database ZFP42 NACC1 MI:0362 inference MI:0461 interaction database NACC1 CDC5L MI:0045 experimental interaction detection MI:0461 interaction database NACC1 MAP3K5 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 ARID3A MI:0362 inference MI:0461 interaction database NACC1 MYBBP1A MI:0362 inference MI:0461 interaction database NACC1 WDR18 MI:0362 inference MI:0461 interaction database NACC1 SALL3 MI:0362 inference MI:0461 interaction database NACC1 FOXP3 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 NANOG MI:0362 inference MI:0461 interaction database NACC1 SENP2 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 SALL1 MI:0362 inference MI:0461 interaction database NACC1 FOXJ2 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 SENP1 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 SALL4 MI:0362 inference MI:0461 interaction database NACC1 FOXA2 MI:0045 experimental interaction detection MI:0461 interaction database NACC1 ZNF281 MI:0362 inference MI:0461 interaction database