Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BRCA 16 105793 105793 + Silent SNP G G A TCGA-B6-A0WW-01A-11D-A10G-09 TCGA-B6-A0WW-10A-01D-A10G-09 g.chr16:105793G>A c.177G>A c.(175-177)caG>caA p.Q59Q COAD 16 105489 105489 + Missense_Mutation SNP G G T TCGA-AA-A00K-01A-02W-A005-10 TCGA-AA-A00K-10A-01W-A005-10 g.chr16:105489G>T c.100G>T c.(100-102)Gcc>Tcc p.A34S COAD 16 105501 105501 + Missense_Mutation SNP G G A TCGA-AZ-6601-01A-11D-1771-10 TCGA-AZ-6601-11A-01D-1771-10 g.chr16:105501G>A c.112G>A c.(112-114)Ggc>Agc p.G38S COAD 16 105855 105855 + Missense_Mutation SNP G G A TCGA-CM-4746-01A-01D-1408-10 TCGA-CM-4746-10A-01D-1408-10 g.chr16:105855G>A c.239G>A c.(238-240)cGt>cAt p.R80H COADREAD 16 105489 105489 + Missense_Mutation SNP G G T TCGA-AA-A00K-01A-02W-A005-10 TCGA-AA-A00K-10A-01W-A005-10 g.chr16:105489G>T c.100G>T c.(100-102)Gcc>Tcc p.A34S COADREAD 16 105501 105501 + Missense_Mutation SNP G G A TCGA-AZ-6601-01A-11D-1771-10 TCGA-AZ-6601-11A-01D-1771-10 g.chr16:105501G>A c.112G>A c.(112-114)Ggc>Agc p.G38S COADREAD 16 105855 105855 + Missense_Mutation SNP G G A TCGA-CM-4746-01A-01D-1408-10 TCGA-CM-4746-10A-01D-1408-10 g.chr16:105855G>A c.239G>A c.(238-240)cGt>cAt p.R80H ESCA 16 105489 105489 + Missense_Mutation SNP G G T TCGA-JY-A6F8-01A-11D-A33E-09 TCGA-JY-A6F8-10A-01D-A33H-09 g.chr16:105489G>T c.100G>T c.(100-102)Gcc>Tcc p.A34S ESCA 16 105489 105489 + Missense_Mutation SNP G G T TCGA-JY-A6FE-01A-11D-A33E-09 TCGA-JY-A6FE-10A-01D-A33H-09 g.chr16:105489G>T c.100G>T c.(100-102)Gcc>Tcc p.A34S HNSC 16 104045 104045 + Missense_Mutation SNP A A G TCGA-CR-7377-01A-11D-2012-08 TCGA-CR-7377-10A-01D-2013-08 g.chr16:104045A>G c.56A>G c.(55-57)gAt>gGt p.D19G HNSC 16 107117 107117 + Missense_Mutation SNP T T C TCGA-MT-A51W-01A-21D-A25Y-08 TCGA-MT-A51W-10A-01D-A25Y-08 g.chr16:107117T>C c.373T>C c.(373-375)Ttc>Ctc p.F125L LUSC 16 107122 107122 + Silent SNP C C T TCGA-33-4533-01A-01D-1267-08 TCGA-33-4533-11A-01D-1267-08 g.chr16:107122C>T c.378C>T c.(376-378)atC>atT p.I126I

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation AML-US 16 108564 108564 single base substitution G A downstream_gene_variant BLCA-CN 16 108995 108995 single base substitution T G downstream_gene_variant BLCA-US 16 109026 109026 single base substitution C T downstream_gene_variant BLCA-US 16 111597 111597 single base substitution C T downstream_gene_variant BRCA-EU 16 100229 100229 single base substitution G C upstream_gene_variant BRCA-EU 16 100546 100546 single base substitution G C upstream_gene_variant BRCA-EU 16 101579 101579 single base substitution C G upstream_gene_variant BRCA-EU 16 103251 103251 single base substitution G A 5_prime_UTR_variant BRCA-EU 16 103251 103251 single base substitution G A upstream_gene_variant BRCA-EU 16 104005 104005 single base substitution G T 5_prime_UTR_variant BRCA-EU 16 104005 104005 single base substitution G T exon_variant BRCA-EU 16 104005 104005 single base substitution G T stop_gained E6* 16G>T BRCA-EU 16 104005 104005 single base substitution G T upstream_gene_variant BRCA-EU 16 104361 104361 single base substitution C G intron_variant BRCA-EU 16 104361 104361 single base substitution C G upstream_gene_variant BRCA-EU 16 104869 104869 single base substitution C A intron_variant BRCA-EU 16 104869 104869 single base substitution C A upstream_gene_variant BRCA-EU 16 104910 104910 single base substitution G A intron_variant BRCA-EU 16 104910 104910 single base substitution G A upstream_gene_variant BRCA-EU 16 105297 105297 single base substitution G C exon_variant BRCA-EU 16 105297 105297 single base substitution G C intron_variant BRCA-EU 16 105297 105297 single base substitution G C upstream_gene_variant BRCA-EU 16 105550 105550 single base substitution G A splice_donor_variant BRCA-EU 16 105550 105550 single base substitution G A splice_region_variant BRCA-EU 16 108280 108280 single base substitution G C downstream_gene_variant BRCA-EU 16 108713 108713 single base substitution C T downstream_gene_variant BRCA-EU 16 108802 108802 single base substitution G C downstream_gene_variant BRCA-EU 16 108914 108914 single base substitution G A downstream_gene_variant BRCA-EU 16 110958 110970 deletion of <=200bp GGGTGGGGATGAG - downstream_gene_variant BRCA-EU 16 112051 112051 single base substitution C T downstream_gene_variant BRCA-EU 16 112063 112063 single base substitution G T downstream_gene_variant BRCA-EU 16 112427 112427 single base substitution G C downstream_gene_variant BRCA-EU 16 112580 112580 single base substitution G A downstream_gene_variant BRCA-EU 16 98939 98939 single base substitution G T upstream_gene_variant BRCA-FR 16 103251 103251 single base substitution G A 5_prime_UTR_variant BRCA-FR 16 103251 103251 single base substitution G A upstream_gene_variant BRCA-FR 16 104005 104005 single base substitution G T 5_prime_UTR_variant BRCA-FR 16 104005 104005 single base substitution G T exon_variant BRCA-FR 16 104005 104005 single base substitution G T stop_gained E6* 16G>T BRCA-FR 16 104005 104005 single base substitution G T upstream_gene_variant BRCA-FR 16 104910 104910 single base substitution G A intron_variant BRCA-FR 16 104910 104910 single base substitution G A upstream_gene_variant BRCA-FR 16 111658 111658 single base substitution C T downstream_gene_variant BRCA-FR 16 112580 112580 single base substitution G A downstream_gene_variant BRCA-FR 16 98933 98933 single base substitution C T upstream_gene_variant BRCA-UK 16 111058 111058 single base substitution G C downstream_gene_variant BRCA-US 16 103474 103474 single base substitution A C 5_prime_UTR_variant BRCA-US 16 103474 103474 single base substitution A C upstream_gene_variant BRCA-US 16 103518 103518 single base substitution G A 5_prime_UTR_variant BRCA-US 16 103518 103518 single base substitution G A upstream_gene_variant BRCA-US 16 103923 103923 single base substitution C G 5_prime_UTR_variant BRCA-US 16 103923 103923 single base substitution C G exon_variant BRCA-US 16 103923 103923 single base substitution C G upstream_gene_variant BRCA-US 16 105793 105793 single base substitution G A exon_variant BRCA-US 16 105793 105793 single base substitution G A splice_acceptor_variant BRCA-US 16 105793 105793 single base substitution G A synonymous_variant Q50Q 150G>A BRCA-US 16 105793 105793 single base substitution G A synonymous_variant Q59Q 177G>A BRCA-US 16 109808 109808 single base substitution C T downstream_gene_variant BRCA-US 16 111120 111120 single base substitution A C downstream_gene_variant BTCA-JP 16 101710 101710 deletion of <=200bp A - upstream_gene_variant BTCA-JP 16 104052 104052 single base substitution G C exon_variant BTCA-JP 16 104052 104052 single base substitution G C synonymous_variant P12P 36G>C BTCA-JP 16 104052 104052 single base substitution G C synonymous_variant P21P 63G>C BTCA-JP 16 104052 104052 single base substitution G C upstream_gene_variant BTCA-JP 16 108329 108329 single base substitution C T downstream_gene_variant BTCA-JP 16 109061 109061 single base substitution C T downstream_gene_variant BTCA-JP 16 109222 109222 single base substitution C T downstream_gene_variant CESC-US 16 109765 109765 single base substitution G A downstream_gene_variant COAD-US 16 105501 105501 single base substitution G A exon_variant COAD-US 16 105501 105501 single base substitution G A missense_variant G29S 85G>A COAD-US 16 105501 105501 single base substitution G A missense_variant G38S 112G>A COAD-US 16 105855 105855 single base substitution G A exon_variant COAD-US 16 105855 105855 single base substitution G A missense_variant R63H 188G>A COAD-US 16 105855 105855 single base substitution G A missense_variant R71H 212G>A COAD-US 16 105855 105855 single base substitution G A missense_variant R80H 239G>A COAD-US 16 108363 108363 single base substitution G A downstream_gene_variant COAD-US 16 111222 111222 single base substitution C T downstream_gene_variant COAD-US 16 111226 111226 single base substitution C T downstream_gene_variant COAD-US 16 111247 111247 single base substitution C T downstream_gene_variant COAD-US 16 111961 111961 single base substitution G A downstream_gene_variant COAD-US 16 111967 111967 single base substitution C T downstream_gene_variant COCA-CN 16 107275 107275 single base substitution T G 3_prime_UTR_variant COCA-CN 16 107275 107275 single base substitution T G downstream_gene_variant COCA-CN 16 107275 107275 single base substitution T G exon_variant COCA-CN 16 109149 109149 single base substitution T C downstream_gene_variant COCA-CN 16 109515 109515 single base substitution G A downstream_gene_variant ESAD-UK 16 100210 100210 single base substitution C G upstream_gene_variant ESAD-UK 16 102967 102967 single base substitution G A upstream_gene_variant ESAD-UK 16 106863 106863 single base substitution G A downstream_gene_variant ESAD-UK 16 106863 106863 single base substitution G A intron_variant ESAD-UK 16 109049 109049 single base substitution G A downstream_gene_variant ESAD-UK 16 109811 109811 deletion of <=200bp T - downstream_gene_variant ESAD-UK 16 110238 110238 single base substitution C T downstream_gene_variant ESAD-UK 16 110432 110432 single base substitution C A downstream_gene_variant ESAD-UK 16 111288 111288 single base substitution G A downstream_gene_variant ESAD-UK 16 111570 111570 single base substitution C T downstream_gene_variant ESAD-UK 16 112131 112131 single base substitution G A downstream_gene_variant ESAD-UK 16 98765 98765 single base substitution C T upstream_gene_variant ESAD-UK 16 99338 99338 single base substitution C T upstream_gene_variant ESCA-CN 16 111432 111432 single base substitution T C downstream_gene_variant ESCA-CN 16 111830 111830 single base substitution C T downstream_gene_variant ESCA-CN 16 112618 112618 single base substitution C A downstream_gene_variant KIRC-US 16 103487 103489 deletion of <=200bp TGT - 5_prime_UTR_variant KIRC-US 16 103487 103489 deletion of <=200bp TGT - upstream_gene_variant KIRC-US 16 109255 109255 single base substitution C T downstream_gene_variant KIRC-US 16 109479 109479 single base substitution A G downstream_gene_variant KIRC-US 16 111871 111871 single base substitution C T downstream_gene_variant LAML-KR 16 102189 102189 single base substitution A G upstream_gene_variant LAML-KR 16 105320 105320 single base substitution A G exon_variant LAML-KR 16 105320 105320 single base substitution A G intron_variant LAML-KR 16 105320 105320 single base substitution A G upstream_gene_variant LGG-US 16 111434 111434 single base substitution G A downstream_gene_variant LICA-CN 16 111861 111861 single base substitution G T downstream_gene_variant LICA-FR 16 111849 111849 single base substitution G T downstream_gene_variant LICA-FR 16 112351 112351 single base substitution C T downstream_gene_variant LIHC-US 16 111695 111695 single base substitution C T downstream_gene_variant LINC-JP 16 103472 103472 single base substitution C T 5_prime_UTR_variant LINC-JP 16 103472 103472 single base substitution C T upstream_gene_variant LINC-JP 16 106490 106490 single base substitution A G downstream_gene_variant LINC-JP 16 106490 106490 single base substitution A G exon_variant LINC-JP 16 106490 106490 single base substitution A G intron_variant LINC-JP 16 108991 108991 single base substitution A G downstream_gene_variant LINC-JP 16 111126 111126 single base substitution C G downstream_gene_variant LIRI-JP 16 101423 101423 single base substitution T C upstream_gene_variant LIRI-JP 16 105822 105822 single base substitution C A exon_variant LIRI-JP 16 105822 105822 single base substitution C A missense_variant A52D 155C>A LIRI-JP 16 105822 105822 single base substitution C A missense_variant A60D 179C>A LIRI-JP 16 105822 105822 single base substitution C A missense_variant A69D 206C>A LIRI-JP 16 107096 107096 single base substitution C T 3_prime_UTR_variant LIRI-JP 16 107096 107096 single base substitution C T downstream_gene_variant LIRI-JP 16 107096 107096 single base substitution C T exon_variant LIRI-JP 16 107096 107096 single base substitution C T missense_variant R109W 325C>T LIRI-JP 16 107096 107096 single base substitution C T missense_variant R118W 352C>T LIRI-JP 16 108894 108894 single base substitution T C downstream_gene_variant LIRI-JP 16 112185 112185 single base substitution G C downstream_gene_variant LIRI-JP 16 112667 112667 single base substitution G T downstream_gene_variant LUSC-KR 16 107579 107579 single base substitution G C 3_prime_UTR_variant LUSC-KR 16 107579 107579 single base substitution G C downstream_gene_variant LUSC-KR 16 112513 112513 single base substitution T C downstream_gene_variant LUSC-US 16 107122 107122 single base substitution C T 3_prime_UTR_variant LUSC-US 16 107122 107122 single base substitution C T downstream_gene_variant LUSC-US 16 107122 107122 single base substitution C T exon_variant LUSC-US 16 107122 107122 single base substitution C T synonymous_variant I117I 351C>T LUSC-US 16 107122 107122 single base substitution C T synonymous_variant I126I 378C>T LUSC-US 16 111619 111619 single base substitution C A downstream_gene_variant LUSC-US 16 111894 111894 single base substitution C A downstream_gene_variant MALY-DE 16 111850 111850 single base substitution C T downstream_gene_variant MELA-AU 16 100868 100868 single base substitution T G upstream_gene_variant MELA-AU 16 101025 101025 single base substitution C T upstream_gene_variant MELA-AU 16 101619 101619 single base substitution C T upstream_gene_variant MELA-AU 16 101796 101796 single base substitution G T upstream_gene_variant MELA-AU 16 102755 102755 single base substitution G A upstream_gene_variant MELA-AU 16 102847 102847 single base substitution G A upstream_gene_variant MELA-AU 16 102988 102988 single base substitution A G upstream_gene_variant MELA-AU 16 103103 103103 single base substitution G A 5_prime_UTR_variant MELA-AU 16 103103 103103 single base substitution G A upstream_gene_variant MELA-AU 16 103866 103866 single base substitution G A 5_prime_UTR_variant MELA-AU 16 103866 103866 single base substitution G A upstream_gene_variant MELA-AU 16 104059 104059 single base substitution G A splice_donor_variant MELA-AU 16 104059 104059 single base substitution G A upstream_gene_variant MELA-AU 16 104555 104555 single base substitution C T intron_variant MELA-AU 16 104555 104555 single base substitution C T upstream_gene_variant MELA-AU 16 104802 104802 single base substitution C T intron_variant MELA-AU 16 104802 104802 single base substitution C T upstream_gene_variant MELA-AU 16 105183 105184 multiple base substitution (>=2bp and <=200bp) CC TT exon_variant MELA-AU 16 105183 105184 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 16 105183 105184 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 16 105253 105253 single base substitution T G exon_variant MELA-AU 16 105253 105253 single base substitution T G intron_variant MELA-AU 16 105253 105253 single base substitution T G upstream_gene_variant MELA-AU 16 105491 105492 multiple base substitution (>=2bp and <=200bp) CC TT exon_variant MELA-AU 16 105491 105492 multiple base substitution (>=2bp and <=200bp) CC TT synonymous_variant AL25 MELA-AU 16 105491 105492 multiple base substitution (>=2bp and <=200bp) CC TT synonymous_variant AL34 MELA-AU 16 105491 105492 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 16 105808 105808 single base substitution G A exon_variant MELA-AU 16 105808 105808 single base substitution G A synonymous_variant L47L 141G>A MELA-AU 16 105808 105808 single base substitution G A synonymous_variant L55L 165G>A MELA-AU 16 105808 105808 single base substitution G A synonymous_variant L64L 192G>A MELA-AU 16 107199 107199 single base substitution G A 3_prime_UTR_variant MELA-AU 16 107199 107199 single base substitution G A downstream_gene_variant MELA-AU 16 107199 107199 single base substitution G A exon_variant MELA-AU 16 108861 108861 single base substitution G A downstream_gene_variant MELA-AU 16 110354 110354 single base substitution G T downstream_gene_variant MELA-AU 16 110971 110971 single base substitution G A downstream_gene_variant MELA-AU 16 110974 110974 single base substitution G A downstream_gene_variant MELA-AU 16 111011 111011 single base substitution G A downstream_gene_variant MELA-AU 16 111072 111072 single base substitution G A downstream_gene_variant MELA-AU 16 111475 111476 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU 16 111688 111688 single base substitution G A downstream_gene_variant MELA-AU 16 112113 112113 single base substitution G A downstream_gene_variant MELA-AU 16 112145 112145 single base substitution G A downstream_gene_variant MELA-AU 16 112418 112418 single base substitution C T downstream_gene_variant MELA-AU 16 98112 98112 single base substitution G A upstream_gene_variant MELA-AU 16 98299 98299 single base substitution G A upstream_gene_variant MELA-AU 16 98841 98841 single base substitution G A upstream_gene_variant MELA-AU 16 99291 99291 single base substitution A T upstream_gene_variant MELA-AU 16 99450 99450 single base substitution G A upstream_gene_variant MELA-AU 16 99782 99782 single base substitution G A upstream_gene_variant MELA-AU 16 99854 99854 single base substitution G A upstream_gene_variant ORCA-IN 16 107581 107581 single base substitution G A 3_prime_UTR_variant ORCA-IN 16 107581 107581 single base substitution G A downstream_gene_variant ORCA-IN 16 108588 108588 single base substitution G A downstream_gene_variant ORCA-IN 16 108986 108986 single base substitution G A downstream_gene_variant OV-AU 16 107131 107131 single base substitution G A 3_prime_UTR_variant OV-AU 16 107131 107131 single base substitution G A downstream_gene_variant OV-AU 16 107131 107131 single base substitution G A exon_variant OV-AU 16 107131 107131 single base substitution G A synonymous_variant L120L 360G>A OV-AU 16 107131 107131 single base substitution G A synonymous_variant L129L 387G>A OV-AU 16 110589 110589 single base substitution G A downstream_gene_variant OV-US 16 109279 109279 single base substitution G A downstream_gene_variant PACA-AU 16 102315 102315 single base substitution C T upstream_gene_variant PACA-AU 16 107773 107773 single base substitution T G downstream_gene_variant PACA-CA 16 103631 103631 single base substitution C G 5_prime_UTR_variant PACA-CA 16 103631 103631 single base substitution C G upstream_gene_variant PACA-CA 16 105378 105378 single base substitution C T exon_variant PACA-CA 16 105378 105378 single base substitution C T intron_variant PACA-CA 16 105378 105378 single base substitution C T upstream_gene_variant PACA-CA 16 108680 108680 single base substitution G A downstream_gene_variant PACA-CA 16 109277 109277 single base substitution C T downstream_gene_variant PACA-CA 16 98039 98039 single base substitution G A upstream_gene_variant PACA-CA 16 98290 98292 deletion of <=200bp AAC - upstream_gene_variant PACA-CA 16 98807 98807 single base substitution T C upstream_gene_variant PBCA-DE 16 99066 99066 single base substitution C T upstream_gene_variant PRAD-CA 16 107094 107094 single base substitution T A 3_prime_UTR_variant PRAD-CA 16 107094 107094 single base substitution T A downstream_gene_variant PRAD-CA 16 107094 107094 single base substitution T A exon_variant PRAD-CA 16 107094 107094 single base substitution T A missense_variant I108N 323T>A PRAD-CA 16 107094 107094 single base substitution T A missense_variant I117N 350T>A PRAD-UK 16 103042 103042 single base substitution G C 5_prime_UTR_variant PRAD-UK 16 103042 103042 single base substitution G C upstream_gene_variant PRAD-US 16 108437 108437 single base substitution C T downstream_gene_variant READ-US 16 107107 107107 single base substitution C T 3_prime_UTR_variant READ-US 16 107107 107107 single base substitution C T downstream_gene_variant READ-US 16 107107 107107 single base substitution C T exon_variant READ-US 16 107107 107107 single base substitution C T synonymous_variant D112D 336C>T READ-US 16 107107 107107 single base substitution C T synonymous_variant D121D 363C>T READ-US 16 111247 111247 single base substitution C T downstream_gene_variant SKCA-BR 16 100147 100147 single base substitution T C upstream_gene_variant SKCA-BR 16 101933 101933 single base substitution T A upstream_gene_variant SKCA-BR 16 102775 102796 deletion of <=200bp AAAAAAAAAAAAAAAAAAAAAC - upstream_gene_variant SKCA-BR 16 104846 104846 single base substitution A T intron_variant SKCA-BR 16 104846 104846 single base substitution A T upstream_gene_variant SKCA-BR 16 106942 106942 single base substitution G T downstream_gene_variant SKCA-BR 16 106942 106942 single base substitution G T intron_variant SKCA-BR 16 107876 107876 single base substitution A C downstream_gene_variant SKCA-BR 16 109313 109313 single base substitution G A downstream_gene_variant SKCA-BR 16 109443 109443 single base substitution G A downstream_gene_variant SKCA-BR 16 98928 98928 single base substitution T G upstream_gene_variant SKCM-US 16 101619 101619 single base substitution C T upstream_gene_variant SKCM-US 16 108679 108679 single base substitution C T downstream_gene_variant SKCM-US 16 111654 111654 single base substitution C G downstream_gene_variant SKCM-US 16 111685 111685 single base substitution G A downstream_gene_variant SKCM-US 16 111688 111688 single base substitution G A downstream_gene_variant SKCM-US 16 111912 111912 single base substitution G A downstream_gene_variant SKCM-US 16 112591 112591 single base substitution C T downstream_gene_variant STAD-US 16 108423 108423 single base substitution G A downstream_gene_variant STAD-US 16 108437 108437 single base substitution C T downstream_gene_variant STAD-US 16 108438 108438 single base substitution G A downstream_gene_variant STAD-US 16 108543 108543 single base substitution G T downstream_gene_variant STAD-US 16 108986 108986 single base substitution G A downstream_gene_variant STAD-US 16 109078 109078 single base substitution C T downstream_gene_variant STAD-US 16 111619 111619 single base substitution C T downstream_gene_variant STAD-US 16 112539 112539 single base substitution A C downstream_gene_variant STAD-US 16 112645 112645 single base substitution C T downstream_gene_variant THCA-SA 16 107162 107162 single base substitution C G 3_prime_UTR_variant THCA-SA 16 107162 107162 single base substitution C G downstream_gene_variant THCA-SA 16 107162 107162 single base substitution C G exon_variant UCEC-US 16 105549 105549 single base substitution C T missense_variant P45S 133C>T UCEC-US 16 105549 105549 single base substitution C T missense_variant P54S 160C>T UCEC-US 16 105549 105549 single base substitution C T splice_region_variant UCEC-US 16 105817 105817 single base substitution G T exon_variant UCEC-US 16 105817 105817 single base substitution G T missense_variant K50N 150G>T UCEC-US 16 105817 105817 single base substitution G T missense_variant K58N 174G>T UCEC-US 16 105817 105817 single base substitution G T missense_variant K67N 201G>T UCEC-US 16 108690 108690 single base substitution C A downstream_gene_variant UCEC-US 16 109299 109299 single base substitution C T downstream_gene_variant UCEC-US 16 111823 111823 single base substitution C T downstream_gene_variant UCEC-US 16 111830 111830 single base substitution C T downstream_gene_variant UCEC-US 16 111898 111898 single base substitution C T downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand AOCS-141-3-2 COSM3944345 c.387G>A p.L129L Substitution - coding silent 16:57131-57131 + PD7307a COSM5792782 c.16G>T p.E6* Substitution - Nonsense 16:54005-54005 + BZ34 COSM2141787 c.337C>T p.R113* Substitution - Nonsense 16:56609-56609 + TCGA-BM-6198-01 COSM3420740 c.363C>T p.D121D Substitution - coding silent 16:57107-57107 + BD239T COSM5497264 c.63G>C p.P21P Substitution - coding silent 16:54052-54052 + CSCC-62-T COSM4535771 c.222G>A p.V74V Substitution - coding silent 16:55838-55838 + SJOS011_D COSM5023096 c.181G>A p.A61T Substitution - Missense 16:55797-55797 + TCGA-AX-A0J1-01 COSM966909 c.160C>T p.P54S Substitution - Missense 16:55549-55549 + LOVO COSM1377963 c.239G>A p.R80H Substitution - Missense 16:55855-55855 + RK308_C01 COSM3741753 c.206C>A p.A69D Substitution - Missense 16:55822-55822 + DN11190 COSM5792782 c.16G>T p.E6* Substitution - Nonsense 16:54005-54005 + TCGA-AK-3447-01 COSM1493537 c.326G>T p.R109I Substitution - Missense 16:56598-56598 + TCGA-AA-A00K-01 COSM298517 c.100G>T p.A34S Substitution - Missense 16:55489-55489 + TCGA-CM-4746-01 COSM1377963 c.239G>A p.R80H Substitution - Missense 16:55855-55855 + MS2 COSM1165321 c.56A>C p.D19A Substitution - Missense 16:54045-54045 + TCGA-AP-A0LM-01 COSM966914 c.201G>T p.K67N Substitution - Missense 16:55817-55817 + TCGA-B6-A0WW-01 COSM3817146 c.177G>A p.Q59Q Substitution - coding silent 16:55793-55793 + S01516 COSM5669028 c.63G>T p.P21P Substitution - coding silent 16:54052-54052 + TCGA-AZ-6601-01 COSM1377957 c.112G>A p.G38S Substitution - Missense 16:55501-55501 + RK285_C01 COSM4778990 c.352C>T p.R118W Substitution - Missense 16:57096-57096 + TCGA-33-4533-01 COSM702015 c.378C>T p.I126I Substitution - coding silent 16:57122-57122 + LUAD-S01341 COSM396690 c.93C>A p.S31S Substitution - coding silent 16:55482-55482 + Pat_16_B COSM5850132 c.160+1G>A p.? Unknown 16:55550-55550 + AOCS-141-8-0 COSM3944345 c.387G>A p.L129L Substitution - coding silent 16:57131-57131 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.15277 16p13.3 2412756|CGAP|BC001381|C/G|non-coding||1400|Validated; 2412756|CGAP|BC009179|C/G|non-coding||529|Validated; 1514774|dbSNP|BC001381|C/G|non-coding||1400|Candidate; 1514774|dbSNP|BC009179|C/G|non-coding||529|Candidate

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G Missense p.D19G c.56A>G 16 104045 HNSC C T Synonymous p.I126I c.378C>T 16 107122 LUSC G T Missense p.A34S c.100G>T 16 105489 COREAD