Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 57126650 rs2746349 C T rs2746349 7.80E-06 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 1 57126919 rs2746347 C T rs2746347 4.00E-07 Lymphocyte counts HPOID:0004332|HPOID:0002665 DOID:2841|DOID:1240|DOID:0060058|DOID:614|DOID:1287 G intron GWASdb_trait 1 57157544 rs2179761 G A rs2179761 2.20E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 1 57177388 rs1342382 T A rs1342382 0.00007 Asthma HPOID:0002099 DOID:2841 A UTR-3 GWASdb_trait 1 57177388 rs1342382 T A rs1342382 2.10E-05 Urinary metabolites HPOID:0000079 DOID:557 A UTR-3 GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs2796516 1 57131323 57131323 intronic 0.570581 0.243682694180066 GWAS of prostate cancer rs11206887 1 57116909 57116909 intronic 0.570581 0.243682694180066 GWAS of prostate cancer rs2746342 1 57136249 57136249 intronic 0.246445 0.60827998860456 GWAS of prostate cancer rs2796498 1 57143986 57143986 intronic 0.086819 1.06138522076619 GWAS of prostate cancer rs2796509 1 57149336 57149336 intronic 0.084557 1.07285043377251

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000162409.10 PRKAA2 600497