Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 59120563 rs232860 A G rs232860 2.93E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 T UTR-3 GWASdb_trait 1 59120650 rs232857 C T rs232857 3.97E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A UTR-3 GWASdb_trait 1 59125683 rs232777 C T rs232777 2.80E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 C missense GWASdb_trait 1 59126616 rs232778 A G rs232778 1.97E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait 1 59126676 rs232779 A C rs232779 5.01E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C intron GWASdb_trait 1 59127207 rs232780 T C rs232780 2.80E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 T intron GWASdb_trait 1 59127936 rs6587835 G A rs6587835 2.80E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 G intron GWASdb_trait 1 59128193 rs10430103 A C rs10430103 8.66E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 1 59128237 rs232782 G A rs232782 2.80E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 G intron GWASdb_trait 1 59129516 rs232783 G T rs232783 5.18E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59129644 rs232784 A C rs232784 9.18E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C intron GWASdb_trait 1 59130229 rs232786 A C rs232786 2.83E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 A intron GWASdb_trait 1 59130407 rs232787 C T rs232787 2.83E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 C intron GWASdb_trait 1 59130614 rs232788 C T rs232788 5.14E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59131311 rs232790 G T rs232790 5.13E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59133024 rs232794 T G rs232794 2.82E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 G intron GWASdb_trait 1 59133268 rs232795 A G rs232795 2.82E-04 Depression (quantitative trait) HPOID:0000716 DOID:1596 A intron GWASdb_trait 1 59136875 rs675871 C T rs675871 5.05E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59137273 rs513436 C T rs513436 5.46E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59138172 rs542750 C T rs542750 5.46E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 T intron GWASdb_trait 1 59141365 rs17118097 G A rs17118097 1.44E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 1 59145958 rs4912369 C A rs4912369 6.72E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 A intron GWASdb_trait 1 59146221 rs4912372 A G rs4912372 5.98E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 G intron GWASdb_trait 1 59161678 rs2746083 C A rs2746083 5.19E-04 Suicide attempts in bipolar disorder HPOID:0007302 DOID:3312 C intron GWASdb_trait 1 59162148 rs2811893 T C rs2811893 3.00E-07 Diabetic retinopathy HPOID:0000819|HPOID:0000488 DOID:8947 T intron GWASdb_trait 1 59162148 rs2811893 T C rs2811893 2.50E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 1 59162793 rs6677560 A G rs6677560 1.50E-05 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 1 59165042 rs11207296 A C rs11207296 5.67E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs513436 1 59137273 59137273 intronic 0.980248 0.00866403511788561 GWAS of prostate cancer rs12139511 1 59147926 59147926 exonic 0.963756 0.0160329051705274 GWAS of prostate cancer rs2811893 1 59162148 59162148 intronic 0.876221 0.0573863424899258 GWAS of prostate cancer rs232777 1 59125683 59125683 exonic 0.444347 0.352277747616436

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000162601.9 MYSM1 612176