PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus USP1 PKP1 19615732 biogrid,intact exp GP P P P P P P P G P P P G P P P P P P USP1 TRAF6 23105109 biogrid exp GP GP G G GP G G G GP G GP GP G G G GP G G G G GP G GP G GP GP GP GP G USP1 DTX3 23105109 biogrid exp GP GP G G GP GP G G GP G GP GP G G G GP GP G G G G GP GP GP GP GP GP G USP1 SORT1 26496610 biogrid,intact exp G G G G GP GP G G GP G GP G G G G G GP G G G GP G G GP G G G GP G KATNA1 USP1 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 USP1 20147293,19615732 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 FZR1 23589330,21768287 biogrid exp G GP G G G GP G G GP G GP GP G G G GP GP G G G G G GP GP G GP GP G USP1 KPNA1 26496610,19615732 biogrid,intact exp GP GP G G G GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G ANXA2P2 USP1 19615732 intact exp USP1 LGALS7, LGALS7B 19615732 biogrid,intact exp P USP1 TOR1AIP1 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 JUP 19615732 biogrid,intact exp GP G G G G G G G GP G GP GP G G G GP G G G G GP G GP G GP G GP G G USP1 PHF7 23105109 biogrid exp P GP G G GP P G G P G GP GP G GP G P GP G G G P G GP GP P P GP G USP1 BAG6 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 KRT17 19615732 biogrid,intact exp P P P USP1 CALML3 19615732 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G G G GP GP G G G P G GP GP GP P GP GP G USP1 PCNA 16531995,22989887,21768287,22987070 biogrid exp GP GP G G GP G G G GP G GP G G GP G GP G G G G GP G GP G GP GP GP GP G USP1 EZR 23414517 intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 WDR5 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP1 HSPB1 19615732 biogrid,intact exp GP GP G G GP G G G GP G GP GP G G G GP G G G G GP G GP GP GP G GP GP G USP1 UBE2A 22939629 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP1 UNC45A 22939629 biogrid exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 TAGLN2 19615732 biogrid,intact exp G G G G GP GP G G G G GP G G G G G GP G G G G G G G G G GP G G USP1 RSRP1 26496610 biogrid,intact exp GP GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G USP1 UBA52 i2d exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 ATAD5 20147293,21555454 biogrid exp G G G G G G G G G G G G G G G G G USP1 SGTB 26496610 biogrid,intact exp G G G G G GP G G GP G G G G G GP G G G G G P G G GP G P G SOCS6 USP1 26186194 biogrid exp GP GP G P GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP P GP GP G USP1 CAPNS1 23589330 biogrid exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 ALDH16A1 19615732 biogrid,intact exp GP GP G GP P G GP G GP GP G GP G GP P G GP G P GP GP GP P G USP1 VPS36 22939629 biogrid exp G GP G G G GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G USP1 CALML5 19615732 biogrid,intact exp GP G GP G USP1 LYZ 19615732 biogrid,intact exp G G G GP G G G GP G G GP G GP G G G G G GP GP GP GP G SYNCRIP USP1 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 FLG 19615732 biogrid,intact exp GP USP1 USP43 26496610 biogrid,intact exp GP P G G GP GP P G P GP G P G GP GP G G GP G GP GP GP P GP GP USP1 DSG1 19615732 biogrid,intact exp GP P P P GP P P P P P P USP1 DSC1 19615732 biogrid,intact exp GP P P P G P P P P P P P P P P P P USP1 CERK 26496610 biogrid,intact exp G G G G G GP G G G G GP GP G G G G GP G G G G G G G G G GP GP G USP1 TRIM46 23105109 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP G G P G GP GP GP G G GP G USP1 RPS27A i2d exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 KRT4 19615732 biogrid,intact exp GP GP G G G G G USP1 USP4 19615732 biogrid,intact exp G GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 MYH9 19615732 biogrid,intact exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G VPS26A USP1 22939629 biogrid exp GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 ANAPC1 21768287 biogrid exp P P P P P P P P P P P P P P P USP1 ID2 21925315 biogrid exp, ortho GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UBC 19075014,22195557, 21836163 biogrid,i2d exp, pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PHLPP2 19615732, 25402006 biogrid,intact exp, pred GP G G G GP GP G G GP G G G G G G G GP G G G GP G G GP G GP GP G G USP1 PIR51 26186194, 25402006 biogrid exp, pred P G G P GP GP P P GP GP GP USP1 WDR48 23116119,20147293,22701671,18082604,19075014,25744535,19615732,24850727, 25402006 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G USP1 UBB 15694335, 21836163 hprd,i2d,bci exp, pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 CSE1L 22939629, 25402006 biogrid exp, pred GP G G G G G G G GP G G G G GP G G G G G G GP G G GP G G GP GP G USP1 FANCD2 18082604,15694335, 21836163 hprd,biogrid,i2d exp, pred G G P GP G G GP P G G P P GP G GP GP PHLPP1 USP1 22426999,19615732, 25402006 biogrid,intact exp, pred G GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 BRCA1 23023127 pred P P G GP P P P P P GP P P P P P P P GP USP1 EXOSC8 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 TOPBP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 RRM1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G G GP GP GP GP GP G USP1 CBX3 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 MCM2 25402006 pred GP G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP GP GP GP G PRPF40A USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UFL1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP G GP GP G USP1 MCM6 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G GP GP GP GP GP GP G PSMD10 USP1 21836163 pred GP G G G G GP G G GP G G G G GP G GP GP G G G GP G GP G GP G GP GP G USP1 UCHL5 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PSMA6 21836163 pred P P P P P P P P P P P P P P P P USP1 USP28 23023127 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 TMEM208 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 CDC20 25402006 pred P G GP G GP P P GP G G P GP P GP GP USP1 CDK1 25402006 pred GP G GP G GP P P GP G G G GP GP GP GP GP USP1 UBA2 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G G G GP GP GP GP GP GP G USP1 PSME4 21836163 pred GP GP G G G GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 DEK 25402006 pred GP G G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 NCAPG2 25402006 pred GP P G GP P G G GP P P GP G GP GP G G G P G P P GP GP GP GP DHX15 USP1 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP GP G USP1 EID1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 USP5 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G G GP GP GP GP GP G USP1 UBE2G2 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G G G GP GP GP GP G USP1 RFC5 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PSMA3 21836163 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G GP G GP G GP GP G USP1 SMC4 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UBQLN2 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 LUC7L3 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 HNRNPA2B1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 RFC4 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 PSMC2 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G PSMD9 USP1 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 KHDRBS1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 BTRC 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G DKC1 USP1 25402006 pred P P P P P P P P P P P P P P P P P USP1 FBXW11 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP1 RNF111 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 ACTL6A 25402006 pred GP GP G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 COPS5 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PSMC3 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 CCNA2 25402006 pred G G G G GP G G G GP G G G G GP G GP G G G G G G G GP GP GP GP USP1 SMC5 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G NBN USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 UFD1L 21836163 pred G GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G G GP G USP1 UBE4A 21836163 pred GP GP G G G GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 KIF11 25402006 pred P P G GP P GP P P P GP P P P P P P GP GP USP1 NUSAP1 25402006 pred GP GP G GP G G G GP GP G G GP G GP G G G G GP GP GP GP GP GP GP G USP1 MBD4 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 MCM4 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 SCAF11 25402006 pred GP G G G G GP G G GP G GP GP G GP G GP GP G G G GP G G GP GP GP GP GP G GMNN USP1 25402006 pred GP G G G G G G G GP G G G G GP G GP G G G G GP G G G GP G GP GP G USP1 PSMD2 21836163 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP GP GP GP G USP1 MAGOH 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PSMD4 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 SUZ12 25402006 pred G G G G GP G G G GP G GP G G GP G GP G G G G GP G G G GP G GP G G USP1 MAVS 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G BUB3 USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 NASP 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 H2AFZ 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G CHEK1 USP1 25402006 pred G G G GP USP1 ADRM1 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 NAE1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 STIL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G USP1 FANCL 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 SCFD1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP1 NUP153 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G XPO1 USP1 25402006 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G G G GP G GP GP GP GP GP GP G HAT1 USP1 25402006 pred GP GP G G GP G G G GP G GP G G GP G GP G G G G GP G GP GP GP G GP GP G USP1 RPN1 21836163 pred G GP G G GP GP G G GP G G GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UBA7 21836163 pred P P P P P P P P P P P P P P USP1 PSMC1 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP GP GP GP G USP12 USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G PSMD3 USP1 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G PSMD14 USP1 21836163 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G G GP GP G GP GP G USP1 HNRNPA3 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 DUT 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 TMEM161A 23023127 pred GP GP G G GP GP G G GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G RAD21 USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PNN 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 USP46 25402006 pred GP GP G P GP G G GP G GP P G GP GP GP G G G GP G GP GP GP GP GP GP G USP1 NCL 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 TTK 25402006 pred P P G GP P GP P P P GP P P P P GP P GP GP USP1 DTL 25402006 pred P P G GP P G P P G P G P P G G G GP USP1 UBA3 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 SNIP1 21836163 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G USP1 CEBPG 23023127 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G G GP GP GP GP GP G SRSF10 USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G HNRNPR USP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PGAM1 21836163 pred GP GP G G G GP G G GP G GP GP G GP G GP GP G G G GP G GP G GP G GP GP G USP1 WDR20 25402006 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G G GP GP G GP GP G USP1 DMWD 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G USP1 NEDD8 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 H2AFV 25402006 pred GP G G G G GP G G GP G G G G G G GP GP G G G G G GP G GP G GP GP G USP1 HDAC2 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 COPS8 21836163 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G GP G USP1 FBXO5 25402006 pred P P G GP P GP P P P GP P G P P P GP GP P P USP1 SERBP1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 USP8 25402006 pred G GP G G GP GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G USP1 SMC3 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 MSH2 25402006 pred GP P G G GP GP G G GP G GP P P G GP GP G G G GP G GP GP GP GP GP GP G USP1 HMGB2 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 PHF20 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 DNMT1 25402006 pred G G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP G GP GP G USP1 EYA3 23023127 pred G G G G G G G G GP G G G G GP G GP G G G G G G G G GP G G GP G CBX3 USP1 25402006 pred USP1 SRSF11 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 POMP 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP G GP GP G USP1 BCLAF1 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UTP18 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 GDAP1 21836163 pred G GP G P GP G GP G GP G GP G P GP G G G P G P GP GP G GP GP USP1 TRA2B 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G DNM1L USP1 21836163 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 UBE2D1 21836163 pred GP G G G GP GP G G GP G GP GP G GP G G GP G G G GP G G GP G GP GP GP G USP1 RECQL 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 MRPL3 25402006 pred GP GP G G GP GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G USP1 PSMA4 25402006 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP G G G GP G GP GP GP GP GP GP G USP1 FANCI 25402006 pred GP P G GP GP G GP G GP GP GP G GP GP G G GP G GP P GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BXW9-1 O94782 - 15694335 - X 2 P0CG47 O94782 - 15694335 - X 2 P55060 O94782 biochemical 22939629 colocalization X 2 Q7Z4K8 O94782 two hybrid 23105109 direct interaction X 2 Q86VN1 O94782 biochemical 22939629 colocalization X 2 Q6ZVD8 O94782 affinity chromatography technology 19615732 physical association X 2 P47929 O94782 affinity chromatography technology 19615732 physical association X 2 Q9H1A4 O94782 affinity chromatography technology 21768287 physical association X 2 Q9UM11 O94782 affinity chromatography technology 23589330 physical association X 2 Q8TAF3 O94782 pull down 23116119 direct interaction X 2 Q8TAF3 O94782 imaging technique 22701671 colocalization X 2 Q8TAF3 O94782 affinity chromatography technology 22701671 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 19075014 physical association X 2 Q8TAF3 O94782 biochemical 19075014 colocalization X 2 Q8TAF3 O94782 affinity chromatography technology 19075014 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 18082604 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 24850727 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 24850727 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 19615732 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 19615732 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 20147293 physical association X 2 Q8TAF3 O94782 affinity chromatography technology 18082604 physical association X 2 Q8TAF3 O94782 biochemical 18082604 association X 2 Q8TAF3 O94782 affinity chromatography technology 18082604 physical association X 2 Q8TAF3 O94782 pull down 18082604 direct interaction X 2 Q8TAF3 O94782 pull down 18082604 direct interaction X 2 Q96QE3 O94782 affinity chromatography technology 20147293 physical association X 2 Q96QE3 O94782 affinity chromatography technology 20147293 physical association X 2 Q96QE3 O94782 affinity chromatography technology 21555454 physical association X 2 O94782 O75436 biochemical 22939629 colocalization X 2 O94782 A0A024R336 two hybrid 23105109 direct interaction X 2 O94782 P04792 affinity chromatography technology 19615732 physical association X 2 O94782 P14923 affinity chromatography technology 19615732 physical association X 2 O94782 Q04695 affinity chromatography technology 19615732 physical association X 2 O94782 Q9BXW9-3 affinity chromatography technology 15694335 physical association X 2 O94782 Q9BXW9-3 enzymatic study 18082604 direct interaction X 2 O94782 Q02363 affinity chromatography technology 21925315 physical association X 2 O94782 Q02363 affinity chromatography technology 21925315 physical association X 2 A0A024RB96 O94782 two hybrid 23105109 direct interaction X 2 P20930 O94782 affinity chromatography technology 19615732 physical association X 2 O94782 affinity chromatography technology 19615732 physical association X 2 Q8IZ83-2 O94782 affinity chromatography technology 19615732 physical association X 2 P12830 O94782 affinity chromatography technology 21768287 physical association X 2 P12830 O94782 enzymatic study 21768287 direct interaction X 2 P12830 O94782 affinity chromatography technology 21768287 physical association X 2 P37802 O94782 affinity chromatography technology 19615732 physical association X 2 Q02413 O94782 affinity chromatography technology 19615732 physical association X 2 P27482 O94782 affinity chromatography technology 19615732 physical association X 2 P55854 O94782 affinity chromatography technology 25391492 physical association X 2 P0CG48 O94782 enzymatic study 22195557 direct interaction X 2 P0CG48 O94782 affinity chromatography technology 21963094 physical association X 2 P0CG48 O94782 affinity chromatography technology 24816145 physical association X 2 P0CG48 O94782 pull down 19075014 direct interaction X 2 P0CG48 O94782 affinity chromatography technology 21768287 physical association X 2 P0CG48 O94782 affinity chromatography technology 15694335 physical association X 2 P0CG48 O94782 affinity chromatography technology 22118674 physical association X 2 P0CG48 O94782 affinity chromatography technology 21139048 physical association X 2 P0CG48 O94782 affinity chromatography technology 21890473 physical association X 2 P0CG48 O94782 affinity chromatography technology 21906983 physical association X 2 P12004 O94782 enzymatic study 22989887 direct interaction X 2 P12004 O94782 enzymatic study 22987070 direct interaction X 2 P12004 O94782 affinity chromatography technology 21768287 physical association X 2 P12004 O94782 enzymatic study 16531995 direct interaction X 2 P61964 O94782 biochemical 22939629 colocalization X 2 O94782 O60346 affinity chromatography technology 22426999 physical association X 2 O94782 O60346 affinity chromatography technology 22426999 physical association X 2 O94782 O60346 pull down 22426999 direct interaction X 2 O94782 Q9H3U1-3 biochemical 22939629 colocalization X 2 O94782 Q9Y4K3 two hybrid 23105109 direct interaction X 2 O94782 P04632 affinity chromatography technology 23589330 physical association X 2 O94782 P04632 affinity chromatography technology 23589330 physical association X 2 O94782 Q08554 affinity chromatography technology 19615732 physical association X 2 O94782 P52294 affinity chromatography technology 19615732 physical association X 2 O94782 B2R4C5 affinity chromatography technology 19615732 physical association X 2 O94782 A0A024R1N1 affinity chromatography technology 19615732 physical association X 2 O94782 A0A024R952 affinity chromatography technology 19615732 physical association X 2 O94782 Q13107-3 affinity chromatography technology 19615732 physical association X 2 O94782 O60346 affinity chromatography technology 19615732 physical association X 2 O94782 O60346 affinity chromatography technology 19615732 physical association X 2 O94782 Q9NZT1 affinity chromatography technology 19615732 physical association X 2 O94782 O94782 affinity chromatography technology 20147293 physical association X 2 O94782 P61956-2 affinity chromatography technology 21693764 physical association X 2 O94782 P61956-2 affinity chromatography technology 19471022 physical association X 2 P49459-3 O94782 biochemical 22939629 colocalization X 2 Q8TAF3 O94782 affinity chromatography technology 18082604 association X 2 Q8TAF3 O94782 anti bait coimmunoprecipitation 18082604 association X 2 P0CG47 O94782 in vivo 15694335 - X 2 P0CG47 O94782 in vivo 15694335 - X 2 A0A024R2G2 O94782 in vivo 15694335 - X 2 A0A024R2G2 O94782 in vivo 15694335 - X 2 O94782 anti tag coimmunoprecipitation 19615732 physical association C 59 O94782 P15311 two hybrid fragment pooling approach 23414517 physical association X 2 O94782 anti tag coimmunoprecipitation 19615732 physical association C 15 O94782 anti tag coimmunoprecipitation 19615732 physical association C 12

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B USP1 KPNA1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119537|UniProt_100689 bait|bait prey|prey VPS26A USP1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238129 prey bait USP1 UNC45A MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_239486 bait prey USP1 KRT4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119543|UniProt_100689 bait|bait prey|prey USP1 VPS36 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240147 bait prey USP1 PHLPP2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119848|UniProt_100715 prey|prey bait|bait USP1 UBA52 MI:0493(in vivo) 15694335 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_26937 - - USP1 USP4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119847|UniProt_100689 bait|bait prey|prey USP1 LGALS7 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119568|UniProt_100689 bait|bait prey|prey USP1 PKP1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119654|UniProt_100689 bait|bait prey|prey USP1 KRT17 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119549|UniProt_100689 bait|bait prey|prey USP1 LYZ MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119571|UniProt_100689 bait|bait prey|prey USP1 WDR5 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_238850 bait prey USP1 SUMO2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19471022,21693764 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_165624|BIOGRID_183442 prey|prey bait|bait USP1 DTX3 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248199 bait prey USP1 ATAD5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20147293 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_136634|BIOGRID_136636 bait|bait prey|prey USP1 JUP MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119533|UniProt_100689 bait|bait prey|prey USP1 TRIM46 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248198 bait prey USP1 FANCD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 15694335,18082604 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_129238|BIOGRID_139423|HPRD_18144 bait|bait|- prey|prey|- USP1 PHF7 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248197 bait prey USP1 TAGLN2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119909|UniProt_100689 bait|bait prey|prey USP1 CALML3 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119374|UniProt_100689 bait|bait prey|prey USP1 UBE2A MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_241577 prey bait USP1 WDR48 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 18082604,19615732,20147293,22701671,23116119 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) UniProt_100725|BIOGRID_139417|BIOGRID_247850|BIOGRID_139418|BIOGRID_139419|BIOGRID_247849|BIOGRID_136635|BIOGRID_247479|BIOGRID_139416|BIOGRID_139420|BIOGRID_119850|BIOGRID_120604|UniProt_100689 prey|bait|bait|bait|bait|prey|bait|bait|bait|prey|prey|bait|bait bait|prey|prey|prey|prey|bait|prey|prey|prey|bait|bait|prey|prey USP1 ALDH16A1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120804|UniProt_100689 bait|bait prey|prey USP1 EZR MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_127080 prey bait USP1 UBC MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15694335,21139048,21890473,21906983,21963094,22118674,22195557 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_199458|BIOGRID_179213|BIOGRID_176768|BIOGRID_160465|BIOGRID_169933|BIOGRID_129237|BIOGRID_265298 bait|prey|prey|prey|prey|bait|prey prey|bait|bait|bait|bait|prey|bait USP1 FLG MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119476|UniProt_100689 bait|bait prey|prey USP1 CSE1L MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242788 bait prey USP1 DSC1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119447|UniProt_100689 bait|bait prey|prey USP1 PCNA MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 16531995,22987070,22989887 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_218260|BIOGRID_139994|BIOGRID_217803 bait|bait|bait prey|prey|prey PHLPP1 USP1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 19615732,22426999 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact) BIOGRID_119849|BIOGRID_218970|BIOGRID_218969|BIOGRID_218971|BIOGRID_120294|UniProt_100716|UniProt_100689 bait|prey|bait|prey|prey|bait|prey prey|bait|prey|bait|bait|prey|bait USP1 TRAF6 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248196 bait prey USP1 MYH9 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119595|UniProt_100689 bait|bait prey|prey USP1 DSG1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119449|UniProt_100689 bait|bait prey|prey USP1 ID2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21925315 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_155008|BIOGRID_155007 bait|prey prey|bait USP1 CALML5 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_120482|UniProt_100689 bait|bait prey|prey USP1 HSPB1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_119520|UniProt_100689 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality ANXA2P2 USP1 19615732,19615732 0004,0007 HT B4DRS2 USP1 19615732 0004 HT SOCS6 USP1 26186194 0004 HT PHLPP1 USP1 22426999,19615732,19615732,22426999 0004,0004,0007,0096 LC,HT SYNCRIP USP1 26496610 0007 HT VPS26A USP1 22939629 0401 HT KATNA1 USP1 26496610,26496610 0007,0004 HT USP1 HSPB1 19615732,19615732 0004,0007 HT USP1 UBC 15694335,22118674,19075014 0004,0004,0096 LC USP1 JUP 19615732,19615732 0004,0007 HT USP1 KRT4 19615732 0007 HT USP1 FLG 19615732,19615732 0004,0007 HT USP1 CALML3 19615732,19615732 0004,0007 HT USP1 MYH9 19615732,19615732 0004,0007 HT USP1 TAGLN2 19615732,19615732 0004,0007 HT USP1 BAG6 26496610,26496610 0007,0004 HT USP1 LGALS7|LGALS7B 19615732,19615732 0004,0007 HT USP1 UBE2A 22939629 0401 HT USP1 KPNA1 26496610,19615732,19615732,26496610 0007,0004,0007,0004 HT USP1 CSE1L 22939629 0401 HT USP1 LYZ 19615732,19615732 0004,0007 HT USP1 WDR5 22939629 0401 HT USP1 DSG1 19615732,19615732 0004,0007 HT USP1 KRT17 19615732,19615732 0004,0007 HT USP1 DSC1 19615732,19615732 0004,0007 HT USP1 USP4 19615732,19615732 0004,0007 HT USP1 PKP1 19615732,19615732 0004,0007 HT USP1 Q14666 19615732 0004 HT USP1 Q59GL1 26496610 0004 HT USP1 TOR1AIP1 26496610,26496610 0007,0004 HT USP1 PHLPP2 19615732,19615732 0004,0007 HT USP1 USP43 26496610,26496610 0007,0004 HT USP1 VPS36 22939629 0401 HT USP1 ALDH16A1 19615732,19615732 0004,0007 HT USP1 WDR48 18082604,19075014,18082604,18082604,19615732,25744535,19075014,23116119,25744535,20147293,22701671,19615732,24850727,22701671,26388029,18082604 0096,0004,0401,0004,0004,0428,0401,0096,0004,0004,0004,0007,0004,0428,0004,0006 LC,HT USP1 CERK 26496610,26496610 0007,0004 HT USP1 RAD51AP1 26186194 0004 HT USP1 SGTB 26496610,26496610 0007,0004 HT USP1 ATAD5 20147293,21555454 0004,0004 LC USP1 SORT1 26496610,26496610 0007,0004 HT USP1 RSRP1 26496610,26496610 0007,0004 HT USP1 UNC45A 22939629 0401 HT USP1 CALML5 19615732,19615732 0004,0007 HT USP1 FZR1 23589330,21768287,21768287 0004,0004,0415 LC USP1 HEL-S-102 19615732 0004 HT ANXA2P2 USP1 19615732,19615732 0004,0007 HT B4DRS2 USP1 19615732 0004 HT SOCS6 USP1 26186194 0004 HT PHLPP1 USP1 19615732,19615732 0004,0007 HT SYNCRIP USP1 26496610 0007 HT VPS26A USP1 22939629 0401 HT KATNA1 USP1 26496610,26496610 0007,0004 HT USP1 HSPB1 19615732,19615732 0004,0007 HT USP1 JUP 19615732,19615732 0004,0007 HT USP1 KRT4 19615732 0007 HT USP1 FLG 19615732,19615732 0004,0007 HT USP1 CALML3 19615732,19615732 0004,0007 HT USP1 MYH9 19615732,19615732 0004,0007 HT USP1 TAGLN2 19615732,19615732 0004,0007 HT USP1 BAG6 26496610,26496610 0007,0004 HT USP1 LGALS7|LGALS7B 19615732,19615732 0004,0007 HT USP1 UBE2A 22939629 0401 HT USP1 KPNA1 26496610,19615732,19615732,26496610 0007,0004,0007,0004 HT USP1 CSE1L 22939629 0401 HT USP1 LYZ 19615732,19615732 0004,0007 HT USP1 WDR5 22939629 0401 HT USP1 DSG1 19615732,19615732 0004,0007 HT USP1 KRT17 19615732,19615732 0004,0007 HT USP1 DSC1 19615732,19615732 0004,0007 HT USP1 USP4 19615732,19615732 0004,0007 HT USP1 PKP1 19615732,19615732 0004,0007 HT USP1 Q14666 19615732 0004 HT USP1 Q59GL1 26496610 0004 HT USP1 TOR1AIP1 26496610,26496610 0007,0004 HT USP1 PHLPP2 19615732,19615732 0004,0007 HT USP1 USP43 26496610,26496610 0007,0004 HT USP1 VPS36 22939629 0401 HT USP1 ALDH16A1 19615732,19615732 0004,0007 HT USP1 WDR48 19615732,19615732 0004,0007 HT USP1 CERK 26496610,26496610 0007,0004 HT USP1 RAD51AP1 26186194 0004 HT USP1 SGTB 26496610,26496610 0007,0004 HT USP1 SORT1 26496610,26496610 0007,0004 HT USP1 RSRP1 26496610,26496610 0007,0004 HT USP1 UNC45A 22939629 0401 HT USP1 CALML5 19615732,19615732 0004,0007 HT USP1 HEL-S-102 19615732 0004 HT PHLPP1 USP1 22426999,22426999 0004,0096 LC USP1 UBC 15694335,22118674,19075014 0004,0004,0096 LC USP1 WDR48 18082604,19075014,18082604,18082604,25744535,19075014,23116119,25744535,20147293,22701671,24850727,22701671,26388029,18082604 0096,0004,0401,0004,0428,0401,0096,0004,0004,0004,0004,0428,0004,0006 LC USP1 ATAD5 20147293,21555454 0004,0004 LC USP1 FZR1 23589330,21768287,21768287 0004,0004,0415 LC VPS26A USP1 22939629 0401 LC USP1 UBB 15694335 0019 LC USP1 UBC 22195557 0415 LC USP1 PCNA 22989887,16531995,22987070 0415,0415,0415 LC USP1 EZR 23414517 0399 HT USP1 UBE2A 22939629 0401 LC USP1 CSE1L 22939629 0401 LC USP1 WDR5 22939629 0401 LC USP1 TRIM46 23105109 0018 LC USP1 VPS36 22939629 0401 LC USP1 DTX3 23105109 0018 LC USP1 WDR48 18082604,19075014,18082604,18082604,19075014,18082604 0096,0004,0401,0004,0401,0006 LC USP1 FANCD2 18082604,15694335,15694335,15694335 0415,0019,0004,0401 LC USP1 UNC45A 22939629 0401 LC USP1 Q9NS08 23105109 0018 LC USP1 FZR1 21768287,21768287 0004,0415 LC USP1 TRAF6 23105109 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5JTV8 O94782 TOR1AIP1 USP1 0.126 26496610 O94782 O60506 USP1 SYNCRIP 0.126 26496610 Q9H1A4 O94782 ANAPC1 USP1 0.21 21768287 Q8TCT0 O94782 CERK USP1 0.126 26496610 O94782 O75449 USP1 KATNA1 0.126 26496610 Q70EL4 O94782 USP43 USP1 0.126 26496610 P0CG48 O94782 UBC USP1 0.523 19075014,22195557 O94782 A6NMY6 USP1 ANXA2P2 0.126 19615732 O94782 O75436 USP1 VPS26A 0.081 22939629 O94782 O94782 USP1 USP1 0.236 20147293 P15311 O94782 EZR USP1 0.126 23414517 P19013 O94782 KRT4 USP1 0.126 19615732 P55060 O94782 CSE1L USP1 0.081 22939629 P61964 O94782 WDR5 USP1 0.081 22939629 Q7Z4K8 O94782 TRIM46 USP1 0.183 23105109 Q86VN1 O94782 VPS36 USP1 0.081 22939629 Q8N9I9 O94782 DTX3 USP1 0.183 23105109 Q9BWX1 O94782 PHF7 USP1 0.183 23105109 Q9H3U1 O94782 UNC45A USP1 0.081 22939629 Q9UM11 O94782 FZR1 USP1 0.659 21768287,23589330 Q9Y4K3 O94782 TRAF6 USP1 0.183 23105109 P12004 O94782 PCNA USP1 0.74 22989887,22987070,21768287,16531995 P04632 O94782 CAPNS1 USP1 0.21 23589330 Q9Z0Y1 O94782 DCTN3 USP1 0.236 26496610 Q91XU3 O94782 PIP4K2C USP1 0.236 26496610 Q6ZVD8 O94782 PHLPP2 USP1 0.236 19615732 Q8BH57 O94782 WDR48 USP1 0.236 26496610 Q02413 O94782 DSG1 USP1 0.236 19615732 P14923 O94782 JUP USP1 0.236 19615732 P04792 O94782 HSPB1 USP1 0.236 19615732 P61626 O94782 LYZ USP1 0.236 19615732 P35579 O94782 MYH9 USP1 0.236 19615732 P20930 O94782 FLG USP1 0.236 19615732 P27482 O94782 CALML3 USP1 0.236 19615732 P37802 O94782 TAGLN2 USP1 0.236 19615732 P47929 O94782 LGALS7B USP1 0.236 19615732 Q13107 O94782 USP4 USP1 0.236 19615732 Q04695 O94782 KRT17 USP1 0.236 19615732 Q08554 O94782 DSC1 USP1 0.236 19615732 Q13835 O94782 PKP1 USP1 0.236 19615732 Q8IZ83 O94782 ALDH16A1 USP1 0.236 19615732 Q9NZT1 O94782 CALML5 USP1 0.236 19615732 O94782 O60346 USP1 PHLPP1 0.748 22426999,19615732 Q9BXW9 O94782 FANCD2 USP1 0.523 15694335,18082604 Q8TAF3 O94782 WDR48 USP1 0.988 20147293,26388029,24850727,23116119,19075014,19615732,22701671,18082604,25744535 Q96B01 O94782 RAD51AP1 USP1 0.126 26186194 Q96EQ0 O94782 SGTB USP1 0.126 26496610 Q96QE3 O94782 ATAD5 USP1 0.309 20147293,21555454 Q9BUV0 O94782 RSRP1 USP1 0.126 26496610 Q99523 O94782 SORT1 USP1 0.126 26496610 P46379 O94782 BAG6 USP1 0.126 26496610 P49459 O94782 UBE2A USP1 0.081 22939629 P52294 O94782 KPNA1 USP1 0.332 26496610,19615732 Q02363 O94782 ID2 USP1 0.376 21925315

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 ANXA2P2 USP1 MI:0045 experimental interaction detection MI:0461 interaction database STRA13 USP1 MI:0362 inference MI:1106 pathways database SOCS6 USP1 MI:0045 experimental interaction detection MI:0461 interaction database FANCG USP1 MI:0362 inference MI:1106 pathways database FANCA USP1 MI:0362 inference MI:1106 pathways database PHLPP1 USP1 MI:0045 experimental interaction detection MI:0461 interaction database SYNCRIP USP1 MI:0045 experimental interaction detection MI:0461 interaction database KATNA1 USP1 MI:0045 experimental interaction detection MI:0461 interaction database DCTN3 USP1 MI:0362 inference MI:0461 interaction database USP1 MYC MI:0045 experimental interaction detection MI:0461 interaction database USP1 CAPNS1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 HSPB1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 UBB MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database USP1 UBC MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database USP1 PCNA MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database USP1 JUP MI:0045 experimental interaction detection MI:0461 interaction database USP1 EZR MI:0045 experimental interaction detection MI:0461 interaction database USP1 RPA2 MI:0362 inference MI:1106 pathways database USP1 KRT4 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FLG MI:0045 experimental interaction detection MI:0461 interaction database USP1 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 CALML3 MI:0045 experimental interaction detection MI:0461 interaction database USP1 RPA1 MI:0362 inference MI:1106 pathways database USP1 RPA3 MI:0362 inference MI:1106 pathways database USP1 RFC4 MI:0362 inference MI:1106 pathways database USP1 RFC2 MI:0362 inference MI:1106 pathways database USP1 RFC1 MI:0362 inference MI:1106 pathways database USP1 MYH9 MI:0045 experimental interaction detection MI:0461 interaction database USP1 TAGLN2 MI:0045 experimental interaction detection MI:0461 interaction database USP1 RFC5 MI:0362 inference MI:1106 pathways database USP1 RFC3 MI:0362 inference MI:1106 pathways database USP1 HNF4A MI:0045 experimental interaction detection MI:0461 interaction database USP1 BAG6 MI:0045 experimental interaction detection MI:0461 interaction database USP1 LGALS7 MI:0045 experimental interaction detection MI:0461 interaction database USP1 PIP4K2A MI:0362 inference MI:0461 interaction database USP1 KPNA1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 SUMO3 MI:0045 experimental interaction detection MI:0461 interaction database USP1 MAX MI:0045 experimental interaction detection MI:0461 interaction database USP1 LYZ MI:0045 experimental interaction detection MI:0461 interaction database USP1 SUMO2 MI:0045 experimental interaction detection MI:0461 interaction database USP1 RPS27A MI:0362 inference MI:1106 pathways database USP1 UBA52 MI:0362 inference MI:1106 pathways database USP1 PIP4K2B MI:0362 inference MI:0461 interaction database USP1 FANCC MI:0362 inference MI:1106 pathways database USP1 E2F1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 ID2 MI:0045 experimental interaction detection MI:0461 interaction database USP1 DSG1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 KRT17 MI:0045 experimental interaction detection MI:0461 interaction database USP1 DSC1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 RBL2 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FAAP100 MI:0362 inference MI:1106 pathways database USP1 USP4 MI:0045 experimental interaction detection MI:0461 interaction database USP1 PKP1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 E2F4 MI:0045 experimental interaction detection MI:0461 interaction database USP1 TOR1AIP1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FAAP20 MI:0362 inference MI:1106 pathways database USP1 PHLPP2 MI:0045 experimental interaction detection MI:0461 interaction database USP1 USP43 MI:0045 experimental interaction detection MI:0461 interaction database USP1 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database USP1 MIB1 MI:0362 inference MI:0461 interaction database USP1 FANCM MI:0362 inference MI:1106 pathways database USP1 ALDH16A1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 APITD1 MI:0362 inference MI:1106 pathways database USP1 DTX3 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FANCB MI:0362 inference MI:1106 pathways database USP1 WDR48 MI:0045 experimental interaction detection MI:0461 interaction database USP1 PIP4K2C MI:0362 inference MI:0461 interaction database USP1 CERK MI:0045 experimental interaction detection MI:0461 interaction database USP1 RAD51AP1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 SGTB MI:0045 experimental interaction detection MI:0461 interaction database USP1 ATAD5 MI:0045 experimental interaction detection MI:0461 interaction database USP1 SORT1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FAAP24 MI:0362 inference MI:1106 pathways database USP1 RSRP1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 PHF7 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FANCD2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database USP1 ANAPC1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FANCE MI:0362 inference MI:1106 pathways database USP1 FANCF MI:0362 inference MI:1106 pathways database USP1 FANCI MI:0362 inference MI:1106 pathways database USP1 FANCL MI:0362 inference MI:1106 pathways database USP1 CALML5 MI:0045 experimental interaction detection MI:0461 interaction database USP1 FZR1 MI:0045 experimental interaction detection MI:0461 interaction database USP1 ZBTB32 MI:0362 inference MI:1106 pathways database USP1 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database