PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM58 DYNC2LI1 25241935 biogrid exp G P P P P TRIM58 TRIM58 25241935 biogrid exp P P G GP P G P P P P P P P P P P GP P P P P P P P UBE2D3 TRIM58 25241935 biogrid exp P G GP P G P P P P P P P P GP P P P P P DYNC1I1 TRIM58 25241935 biogrid exp P G G P G P P P P G P P P DYNC1H1 TRIM58 25241935 biogrid exp P P G GP P G P P P P P P P P P GP P P P P P P DYNC1LI2 TRIM58 25241935 biogrid exp G G G G TRIM58 UBE2E2 23023127 pred P P G GP P G P P P P P P P P P P GP P P P P P P P UBE2NL TRIM58 23023127 pred G G G G TRIM58 STUB1 23023127 pred P P G GP P G P P P P P P P P P P GP P P P P P P P UBE2N TRIM58 23023127 pred P P G GP P G P P P P P P P P P GP P P P P P P P UBE2E1 TRIM58 23023127 pred P P G G P G P P P P P P GP P P P P TRIM58 RNF39 23023127 pred P G GP P G P P P P P P P P GP P P P P TRIM58 RNF39 23023127 pred P G GP P G P P P P P P P P GP P P P P UBE2K TRIM58 23023127 pred P P G GP P G P P P P P P P P P P GP P P P P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8NG06 pull down 25241935 direct interaction X 2 Q8NG06 affinity chromatography technology 25241935 physical association X 2 Q8NG06 affinity chromatography technology 25241935 physical association X 2 Q8NG06 affinity chromatography technology 25241935 physical association X 2 Q8NG06 A0A024R6Z0 affinity chromatography technology 25241935 physical association X 2 Q8NG06 enzymatic study 25241935 direct interaction X 2 Q8NG06 Q8NG06 enzymatic study 25241935 direct interaction X 2 Q8NG06 Q14204 affinity chromatography technology 25241935 physical association X 2 Q8NG06 Q14204 affinity chromatography technology 25241935 physical association X 2 Q8NG06 P61077-3 pull down 25241935 direct interaction X 2

PPI - HINT Gene A Gene B PMID Method Quality DYNC1I1 TRIM58 25241935,25241935,25241935 0096,0415,0004 LC TRIM58 TRIM58 25241935 0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8NG06 O43237 TRIM58 DYNC1LI2 0.21 25241935 Q8NG06 P61077 TRIM58 UBE2D3 0.309 25241935 Q8NG06 Q14204 TRIM58 DYNC1H1 0.21 25241935 Q8NG06 Q8NG06 TRIM58 TRIM58 0.332 25241935 Q8TCX1 Q8NG06 DYNC2LI1 TRIM58 0.21 25241935 Q8NG06 O14576 TRIM58 DYNC1I1 0.623 25241935

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 DYNC1I1 TRIM58 MI:0045 experimental interaction detection MI:0461 interaction database DYNC1LI2 TRIM58 MI:0045 experimental interaction detection MI:0461 interaction database UBC TRIM58 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D3 TRIM58 MI:0045 experimental interaction detection MI:0461 interaction database DYNC1H1 TRIM58 MI:0045 experimental interaction detection MI:0461 interaction database TRIM58 DYNC2LI1 MI:0045 experimental interaction detection MI:0461 interaction database