Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 155148781 rs4971059 G A rs4971059 3.02E-09 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 G intron GWASdb_drug 1 155149718 rs3814316 G A rs3814316 6.48E-11 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_drug 1 155151493 rs11264341 C T rs11264341 6.00E-19 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_drug 1 155151754 rs9426886 A T rs9426886 1.12E-14 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_drug 1 155155731 rs4971100 G A rs4971100 1.82E-14 URIC ACID GLUCOSE|INHIBINS Urate levels HPOID:0000079 DOID:13189 G intron GWASdb_drug 1 155148781 rs4971059 G A rs4971059 3.02E-09 Urate levels HPOID:0000079 DOID:13189 G intron GWASdb_trait 1 155149718 rs3814316 G A rs3814316 6.48E-11 Urate levels HPOID:0000079 DOID:13189 C cds-synon GWASdb_trait 1 155151493 rs11264341 C T rs11264341 6.00E-19 Urate levels HPOID:0000079 DOID:13189 C intron GWASdb_trait 1 155151754 rs9426886 A T rs9426886 1.12E-14 Urate levels HPOID:0000079 DOID:13189 T intron GWASdb_trait 1 155155731 rs4971100 G A rs4971100 1.82E-14 Urate levels HPOID:0000079 DOID:13189 G intron GWASdb_trait 1 155157715 rs2070803 A G rs2070803 1.20E-06 Gastric cancer (diffuse-type gastric cancer) HPOID:0012126 DOID:3717 C nearGene-3 GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs4971100 1 155155731 155155731 intronic 0.398583 0.399481228374208 GWAS of prostate cancer rs3814316 1 155149718 155149718 exonic 0.277551 0.556657203591715

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000163462.17 TRIM46 600986