PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BRCA1 TRIM46 22493164 biogrid,intact exp P P G G P P P P P GP P P P P P P P P GP UBE2U TRIM46 19549727 biogrid,intact exp P P P P P P P P P P P P P P P P GP MDM4 TRIM46 22493164 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 USP15 23105109 biogrid exp G GP G G G GP G G GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 TSG101 19549727 biogrid,intact exp GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 UCHL5 23105109 biogrid exp GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TK1 TRIM46 21900206 biogrid,mint,intact exp GP GP G G P G G GP G G GP G GP P G G P G G GP G G TRIM46 RNF7 22493164 biogrid,intact exp GP GP G G G GP G G GP G GP G G G G GP GP GP G P GP G G GP G G GP G TRIM46 CBLC 22493164 biogrid,intact exp P P P P P GP P P P P P P P P TRIM46 USP32 23105109 biogrid exp GP GP G G G GP G GP GP G GP G GP G G GP GP GP G P GP G G GP G G GP G TRIM46 RNF125 22493164 biogrid,intact exp GP GP G G G GP G G GP G GP G GP G G GP GP P GP G P GP GP GP GP G G P G TRIM46 UBE2Z 19549727 biogrid,intact exp GP GP G G G GP G G GP G GP G GP G G GP GP GP G P GP GP GP GP G G GP G OTUD6A TRIM46 23105109 biogrid exp P P P P P P P P P P P P P P P P P NTRK1 TRIM46 25921289 biogrid exp P P P G P P P P P P P P P P P P P TRIM46 AK5 16169070 hprd,biogrid,i2d,mint,intact exp GP P G GP G GP GP G G G GP GP G G P P P GP P G GP G APP TRIM46 21244100 biogrid exp G GP G G G GP G G GP G G G G G G GP GP GP G P GP G G GP G G GP G USP1 TRIM46 23105109 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP G G P G GP GP GP G G GP G USP2 TRIM46 23105109 biogrid exp GP G GP G GP P G GP G GP G P GP P GP G P P GP GP GP GP G TRIM46 TRIM9 22493164, 23023127 biogrid,intact exp, pred G G G G G G G G G G G ATRNL1 TRIM46 23023127 pred GP G G G GP G G GP G GP G GP G P GP GP G P GP GP GP P P G TRIM46 COL20A1 23023127 pred GP GP G G G GP P GP G P P P GP P GP G P P GP GP P G G GP MYBPHL TRIM46 23023127 pred ITGB4 TRIM46 23023127 pred GP GP G GP G GP GP G G GP G G GP GP G G P GP G GP GP G G P G CD300E TRIM46 23023127 pred P P P P P P P P P P P P CD200 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP GP G G GP GP P GP G P GP GP P GP G G P G TRIM46 CADM2 23023127 pred G GP G GP G P P GP P G P P P P P TRIM46 TNN 23023127 pred GP G G G G GP G G GP G P G GP G G GP GP P GP G P P G GP GP G G P G PTPRK TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P G GP G GP G G GP G ATRN TRIM46 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP P GP G P GP G G GP G G GP G TRIM46 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM37 TRIM46 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP GP G P GP GP G GP G G GP G PPP1R3F TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP G P GP GP G GP G G GP G EPHB6 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CNTN5 TRIM46 23023127 pred P P G P P P P P P P P P P P P P P P TRIM46 CLSTN3 23023127 pred GP GP G G G G G P GP G GP G GP G G GP G P GP G P GP GP P GP G G GP G TYRO3 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TNFSF9 TRIM46 23023127 pred GP GP G G G GP G GP GP G P GP G G GP GP P GP G P P GP GP GP G G GP G TRIM46 IGDCC3 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G MYBPC3 TRIM46 23023127 pred G G G G G GP G G G G G G G G G G G G G G G G KIR2DS1 TRIM46 23023127 pred TRIM46 RUSC1 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP G P GP GP GP GP G G GP G OBSCN TRIM46 23023127 pred GP P P GP GP GP P G G P P P P G P GP GP GP GP G G P TRIM46 SH3KBP1 23023127 pred G G G G G GP G G G G G G G G G G GP G G P G G G G G G G G NCAM1 TRIM46 23023127 pred G GP G G G GP G GP GP G G G G G G G GP P G G G G G G G G GP G TRIM46 PHYHIP 23023127 pred G G G G G G G G G G G G G G G G G G PTPRD TRIM46 23023127 pred GP GP G GP G P GP G GP G GP GP GP P P G P GP P P GP P G SYT13 TRIM46 23023127 pred GP G G G GP G GP GP G GP G GP G GP GP P GP G P G G GP GP G GP G IHH TRIM46 23023127 pred P P P P GP P G P GP P P P P GP P GP GP G P G CD83 TRIM46 23023127 pred G G G G G G G G G G G G GP G G G G G G G G G G G G G G TRIM46 CNTN6 23023127 pred GP G GP G P P G P GP P GP P P G P P P P P NFAT5 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G MYOM2 TRIM46 23023127 pred P GP G GP G GP P G GP G P G P GP GP G P GP P GP GP G GP SPTB TRIM46 23023127 pred G G G G G GP G GP G GP G G G G GP GP G G GP G G G TRIM46 RIMS1 23023127 pred P P G G G GP G GP G P P P GP P P G P GP GP GP GP G GP G CD80 TRIM46 23023127 pred G G G G G GP G G G G G G G G G G GP G G P G G G G G G G G CDH18 TRIM46 23023127 pred GP G G G GP G GP P G P G P G P GP GP G P P P P P GP G ESYT3 TRIM46 23023127 pred GP P P G P P GP P G P P P CD8A TRIM46 23023127 pred G G G G G G G G G G G G GP G G G G G G G G G G G G G G PVRL1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP G G GP G G GP G NEURL1 TRIM46 23023127 pred GP G G G GP G G GP G G G G G GP GP G G G G G G G G CDH13 TRIM46 23023127 pred GP G G GP G P G G GP G G TRIM46 SCN3B 23023127 pred P GP G GP G P G P P G P GP P G P G P P NCR1 TRIM46 23023127 pred G G G G G G TRIM46 CNTN3 23023127 pred G GP G GP GP G G G G G GP P G G P G P G G G P MRC1 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SPTBN1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G NPTX1 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G USH2A TRIM46 23023127 pred PTPRB TRIM46 23023127 pred G GP G GP G GP G G GP G GP G G GP GP GP G GP G G GP G G P G NPHS1 TRIM46 23023127 pred P P P P GP P P P P P P P P TRIM46 KIRREL3 23023127 pred P G GP P G P P GP P P P VWA1 TRIM46 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP P GP G GP GP G GP G G GP G APBB1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G G GP GP G P GP GP GP G G G GP G L1CAM TRIM46 23023127 pred G G G G G GP G G GP G GP G G G GP G G G G G G G G TRIM46 FNDC8 23023127 pred P P P P P P P GP TRIM46 CNTN4 23023127 pred GP G GP G G G G G G GP G G GP P G G G TRIM46 RPH3A 23023127 pred G G G G G GP G G G G G G GP G G G GP G G G G G G G G TNXB TRIM46 23023127 pred P P G G GP G P P P G P GP GP P G P P GP GP P P G MYOM1 TRIM46 23023127 pred G G G GP G G G G G G G GP G G G G TRIM46 NPTN 23023127 pred G G G G G GP G G GP G GP G G G G GP GP P G G G GP G GP G G G G BSPRY TRIM46 23023127 pred G GP G G G GP G G GP G G G GP G G G GP G G P G GP G G G GP G FSD2 TRIM46 23023127 pred P P P GP P P P P P P GP P P P GP GP P TRIM46 TRIM63 25402006, 23023127 pred G G G G TRIM46 RUSC2 23023127 pred GP GP G GP G GP GP G GP G GP G G P GP P P G P P GP GP GP G G GP G SYT5 TRIM46 23023127 pred P P G G G GP G P P G P G P P GP P GP G P P P GP P P MYBPC2 TRIM46 23023127 pred P P GP GP P TRIM46 SYT3 23023127 pred G G G G G G G TRIM46 LRIT1 23023127 pred IL12RB1 TRIM46 23023127 pred G G G G G G DCC TRIM46 23023127 pred P P GP P P G P P P GP P P P P P P P CNTN1 TRIM46 23023127 pred G G G GP G GP G G G G G G GP GP G G G G GP G G G G TRIM46 SDK1 23023127 pred GP P P G P GP G P GP G G GP P P GP G P GP P P GP G G GP G DOC2A TRIM46 23023127 pred G G G G G G G G TRIM46 SNED1 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP G P GP G GP GP G G GP G CDON TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G G P GP GP GP GP G G GP G PTPRJ TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G NCAM2 TRIM46 23023127 pred P GP G GP G P GP G P P P GP P G P P GP P P P G TRIM46 BOC 23023127 pred GP GP G G G GP G GP GP G GP GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 IGSF22 23023127 pred P GP G G G GP GP P G GP P G GP GP P G P P P GP GP G G GP SPOCK1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G P G G GP GP GP G P GP G GP GP G G GP G IL27RA TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G NEGR1 TRIM46 23023127 pred G GP G GP G GP G G P GP G G G GP P G GP GP P G G P TRIM46 VSTM2L 23023127 pred P G GP G GP GP G P GP P GP P G G P P P P G G P EPHA8 TRIM46 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP G G P G GP GP GP G G GP G TRIM46 OSMR 23023127 pred GP GP P G GP GP P GP G G P P GP P GP P P P P G IL4R TRIM46 23023127 pred GP GP G G G P G GP GP G GP G GP G G GP GP P GP P G GP P GP G G GP G BZRAP1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G P G TRIM46 ARHGDIG 23023127 pred GP GP G G G GP G GP GP G P P G G GP GP GP G P GP GP GP GP G P G AMPH TRIM46 23023127 pred G G G G GP G G GP G G G G G GP GP G G G G G G G G G SHH TRIM46 23023127 pred GP GP G G G GP G P GP G GP G GP G GP GP P P G P GP P GP GP G GP CLEC12A TRIM46 23023127 pred P G G P P GP P P P P P G EPHA7 TRIM46 23023127 pred P P G GP G G GP G GP P GP GP P P G P GP GP P GP G G CAMTA2 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM46 TMEFF1 23023127 pred P P P P P P P P P P P P P TNC TRIM46 23023127 pred GP GP G G G GP G G GP G GP G G G GP GP G P GP GP G GP G G GP G TRIM46 SMAP2 23023127 pred G GP G G G GP G G G G G G GP G G G GP P GP G P GP G G G G G GP G SCN2B TRIM46 23023127 pred P P G GP G GP GP G P P P GP P P G P P P GP GP P MYLK TRIM46 23023127 pred G G G G G G G G GP G GP G G G G G G G G G G G G G G G G COL7A1 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM46 SORCS1 23023127 pred P P G GP G GP GP G GP G GP GP P P G P GP G P LINGO2 TRIM46 23023127 pred G P G G G GP G GP P G GP P G P GP GP G P P G GP P G GP G TRIM46 ICAM5 23023127 pred G G G GP G GP G ACAN TRIM46 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM46 NEO1 23023127 pred GP GP G G G GP G G GP G GP G GP G G GP GP P GP G P GP G GP GP G G GP G OPCML TRIM46 23023127 pred G G G G G G TRIM46 SYTL2 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 CADM3 23023127 pred G G G G G GP G G GP G G G G GP G G G G G G G TRIM46 ROBO1 23023127 pred GP GP G GP G GP GP G GP GP G G GP GP P P G P GP GP GP GP G G GP G EPHA5 TRIM46 23023127 pred G G G G G G G G G G G G G G G G G TRIM46 TNR 23023127 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G TRIM46 IL12RB2 23023127 pred P P P P P P P P P P P GP G P G P TRIM46 UNC13A 23023127 pred P P G GP G P G P P GP P G P P P P P TBR1 TRIM46 23023127 pred GP G GP G GP P G P P P GP GP G P P GP GP P GP G CLSTN1 TRIM46 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP G P G GP GP GP G G GP G TRIM46 PTPRU 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G TRIM46 C1QTNF4 23023127 pred P G GP P P G P P P GP P G P P P P GP G TRIM46 FSD1 23023127 pred P G GP G G P G P GP P P P P GP TRIM46 ROBO2 23023127 pred P P G GP G P P G P GP P GP P GP G P P P P P G P MYCBP2 TRIM46 23023127 pred G GP G G G GP G GP GP G G G GP G G GP GP GP G GP G G GP G G GP G FN1 TRIM46 23023127 pred G G G G G GP G GP GP G GP G G G G G GP P G G P G G G G G G G G TRIM46 IL22RA1 23023127 pred G G G G G G G G GP G G G GP G G GP G G G G G G GP G GP G FNDC1 TRIM46 23023127 pred GP P P G GP GP P G G GP P P P P P GP GP P G SDK2 TRIM46 23023127 pred G GP G P GP G GP G G G GP G G P G G GP G TRIM46 COL12A1 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP P GP G P GP GP GP GP G G GP G ILDR2 TRIM46 23023127 pred GP GP G G G GP G G GP G GP G GP P GP GP G P GP G P P G GP G TRIM46 SYT4 23023127 pred GP GP G G G GP G GP P G P P GP GP GP G P G G P GP G P TRIM46 CSF3R 23023127 pred G G G G G GP G GP G G G G GP G G G GP G G P G G G G G G GP G COL14A1 TRIM46 23023127 pred GP G G G GP GP G GP G G GP G GP GP G G GP G G P G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8NFA0 Q7Z4K8 two hybrid 23105109 direct interaction X 2 Q7Z4K8 O94782 two hybrid 23105109 direct interaction X 2 Q7Z4K8 two hybrid 22493164 direct interaction X 2 Q7Z4K8 Q9H832 two hybrid 19549727 direct interaction X 2 P04183 Q7Z4K8 two hybrid 21900206 direct interaction X 2 Q96EQ8 Q7Z4K8 two hybrid 22493164 direct interaction X 2 Q7Z4K8 two hybrid 23105109 direct interaction X 2 Q7Z4K8 O75604-2 two hybrid 23105109 direct interaction X 2 Q7Z4K8 Q9Y4E8-2 two hybrid 23105109 direct interaction X 2 Q7Z4K8 Q7L8S5 two hybrid 23105109 direct interaction X 2 Q7Z4K8 unspecified method 20467438 direct interaction X 2 Q7Z4K8 Q9UBF6-2 two hybrid 22493164 direct interaction X 2 Q7Z4K8 O15151-2 two hybrid 22493164 direct interaction X 2 Q7Z4K8 two hybrid 22493164 direct interaction X 2 Q7Z4K8 Q9ULV8 two hybrid 22493164 direct interaction X 2 Q7Z4K8 Q9Y6K8-2 two hybrid 16169070 direct interaction X 2 Q7Z4K8 two hybrid 19549727 direct interaction X 2 Q7Z4K8 Q99816 two hybrid 19549727 direct interaction X 2 Q7Z4K8 Q9Y6K8-3 two hybrid 16169070 - X 2 Q7Z4K8 Q9Y6K8-3 two hybrid 16169070 - X 2 Q7Z4K8 Q9H832 two hybrid array 19549727 physical association X 2 P04183 Q7Z4K8 two hybrid 21900206 physical association X 2 Q96EQ8 Q7Z4K8 two hybrid array 22493164 physical association X 2 P31016 Q7Z4K8 peptide array 20467438 direct interaction X 2 Q7Z4K8 Q9Y6K8 two hybrid pooling approach 16169070 physical association X 2 Q7Z4K8 Q5VVX9 two hybrid array 19549727 physical association X 2 Q7Z4K8 Q99816 two hybrid array 19549727 physical association X 2 Q7Z4K8 Q9C026 two hybrid array 22493164 physical association X 2 Q7Z4K8 P38398 two hybrid array 22493164 physical association X 2 Q7Z4K8 A0A024R990 two hybrid array 22493164 physical association X 2 Q7Z4K8 Q9ULV8 two hybrid array 22493164 physical association X 2 Q9UBF6 Q7Z4K8 two hybrid array 22493164 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TK1 TRIM46 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_157274|UniProt_178181|UniProt_157583 bait|bait|bait prey|prey|prey TRIM46 AK5 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(intact)|(biogrid) HPRD_29949|UniProt_156648|BIOGRID_94073 -|bait|bait -|prey|prey TRIM46 UCHL5 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248158 prey bait TRIM46 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248206 prey bait TRIM46 UBE2Z MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124556|UniProt_101506 prey|prey bait|bait MDM4 TRIM46 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122577|BIOGRID_284133 prey|prey bait|bait USP2 TRIM46 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248171 bait prey NRF1 TRIM46 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_295885 bait prey USP1 TRIM46 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248198 bait prey TRIM46 RNF125 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122580|BIOGRID_284149 bait|bait prey|prey BRCA1 TRIM46 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122576|BIOGRID_284170 prey|prey bait|bait UBE2U TRIM46 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124557|UniProt_101521 bait|bait prey|prey TRIM46 USP32 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248223 prey bait TRIM46 TSG101 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101219|BIOGRID_124558 prey|prey bait|bait TRIM46 RNF7 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122578|BIOGRID_284108 bait|bait prey|prey OTUD6A TRIM46 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248253 bait prey TRIM46 TRIM9 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122450|BIOGRID_283977 bait|prey prey|bait TRIM46 CBLC MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284177|UniProt_122579 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality MDM4 TRIM46 22493164,22493164 0018,0397 HT USP2 TRIM46 23105109 0018 LC USP1 TRIM46 23105109 0018 LC TK1 TRIM46 21900206 0018 HT BRCA1 TRIM46 22493164,22493164 0018,0397 HT MTNR1B TRIM46 26514267 0018 LC UBE2U TRIM46 19549727,19549727 0397,0018 HT OTUD6A TRIM46 23105109 0018 LC TRIM46 Q8N291 16169070 0018 HT TRIM46 USP32 23105109 0018 LC TRIM46 RNF125 22493164,22493164 0018,0397 HT TRIM46 TSG101 19549727,19549727 0397,0018 HT TRIM46 TRIM9 22493164,22493164 0018,0397 HT TRIM46 UBE2Z 19549727,19549727 0397,0018 HT TRIM46 RNF7 22493164,22493164 0018,0397 HT TRIM46 CBLC 22493164,22493164 0018,0397 HT TRIM46 USP15 23105109 0018 LC TRIM46 UCHL5 23105109 0018 LC TRIM46 AK5 16169070,16169070 0018,0398 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8NFA0 Q7Z4K8 USP32 TRIM46 0.183 23105109 Q9Y6K8 Q7Z4K8 AK5 TRIM46 0.286 16169070 Q9Y4E8 Q7Z4K8 USP15 TRIM46 0.183 23105109 Q9Y5K5 Q7Z4K8 UCHL5 TRIM46 0.183 23105109 Q7Z4K8 O75604 TRIM46 USP2 0.183 23105109 Q7Z4K8 Q7L8S5 TRIM46 OTUD6A 0.183 23105109 Q7Z4K8 P04183 TRIM46 TK1 0.332 21900206 Q7Z4K8 P31016 TRIM46 DLG4 0.183 20467438 Q7Z4K8 P49286 TRIM46 MTNR1B 0.183 26514267 Q9H832 Q7Z4K8 UBE2Z TRIM46 0.376 19549727 Q7Z4K8 O94782 TRIM46 USP1 0.183 23105109 Q7Z4K8 P04629 TRIM46 NTRK1 0.126 25921289 Q7Z4K8 P05067 TRIM46 APP 0.183 21244100 Q9C026 Q7Z4K8 TRIM9 TRIM46 0.286 22493164 Q99816 Q7Z4K8 TSG101 TRIM46 0.286 19549727 Q7Z4K8 Q5VVX9 TRIM46 UBE2U 0.286 19549727 Q7Z4K8 O15151 TRIM46 MDM4 0.286 22493164 Q96EQ8 Q7Z4K8 RNF125 TRIM46 0.286 22493164 Q7Z4K8 P38398 TRIM46 BRCA1 0.286 22493164 Q9UBF6 Q7Z4K8 RNF7 TRIM46 0.286 22493164 Q9ULV8 Q7Z4K8 CBLC TRIM46 0.286 22493164

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MDM4 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database USP2 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database USP1 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database TK1 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database APP TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database BRCA1 TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database MTNR1B TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database CALM1 TRIM46 MI:0362 inference MI:0461 interaction database DLG4 TRIM46 MI:0362 inference MI:0461 interaction database UBE2U TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database OTUD6A TRIM46 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 USP32 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 RNF125 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 TSG101 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 TRIM9 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 UBE2Z MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 RNF7 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 CBLC MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 USP15 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 UCHL5 MI:0045 experimental interaction detection MI:0461 interaction database TRIM46 AK5 MI:0045 experimental interaction detection MI:0461 interaction database