Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 5 95091201 rs34899 A G rs34899 3.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 G missense GWASdb_drug 5 95089373 rs11745143 C T rs11745143 7.12E-04 Schizophrenia HPOID:0100753 DOID:5419 C intron GWASdb_trait 5 95091201 rs34899 A G rs34899 3.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 G missense GWASdb_trait 5 95112866 rs3777218 T C rs3777218 3.32E-05 Breast cancer(er negative) HPOID:0003002 DOID:1612 A intron GWASdb_trait 5 95119408 rs888808 T C rs888808 1.94E-05 Longevity HPOID:0000118 NA A intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000164292.12 RHOBTB3 607353