Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 23 15332559 15332559 + Intron SNP C C G TCGA-OR-A5L6-01A-11D-A29I-10 TCGA-OR-A5L6-10C-01D-A29L-10 g.chrX:15332559C>G BLCA 23 15307698 15307698 + Nonsense_Mutation SNP G G A TCGA-DK-AA76-01A-11D-A391-08 TCGA-DK-AA76-10A-01D-A394-08 g.chrX:15307698G>A c.583C>T c.(583-585)Cag>Tag p.Q195* BLCA 23 15311338 15311338 + Missense_Mutation SNP C C G TCGA-DK-A3WW-01A-22D-A23M-08 TCGA-DK-A3WW-10A-01D-A23K-08 g.chrX:15311338C>G c.474G>C c.(472-474)caG>caC p.Q158H BLCA 23 15311407 15311407 + Silent SNP G G C TCGA-ZF-AA54-01A-11D-A391-08 TCGA-ZF-AA54-10A-01D-A394-08 g.chrX:15311407G>C c.405C>G c.(403-405)ctC>ctG p.L135L BLCA 23 15320872 15320872 + Missense_Mutation SNP G G A TCGA-S5-A6DX-01A-11D-A31L-08 TCGA-S5-A6DX-10A-01D-A31J-08 g.chrX:15320872G>A c.239C>T c.(238-240)gCc>gTc p.A80V BLCA 23 15332510 15332510 + Intron SNP A A G TCGA-YF-AA3L-01A-11D-A38G-08 TCGA-YF-AA3L-10A-01D-A38J-08 g.chrX:15332510A>G BRCA 23 15306047 15306047 + Missense_Mutation SNP G G A TCGA-E9-A1RF-01A-11D-A159-09 TCGA-E9-A1RF-10A-01D-A159-09 g.chrX:15306047G>A c.803C>T c.(802-804)gCg>gTg p.A268V BRCA 23 15333633 15333633 + Frame_Shift_Del DEL A A - TCGA-AN-A0AK-01A-21W-A019-09 TCGA-AN-A0AK-10A-01W-A021-09 g.chrX:15333633delA c.95delT c.(94-96)ttgfs p.L32fs COAD 23 15301734 15301734 + Missense_Mutation SNP G G T TCGA-AD-6901-01A-11D-1924-10 TCGA-AD-6901-10A-01D-1924-10 g.chrX:15301734G>T c.865C>A c.(865-867)Cag>Aag p.Q289K COAD 23 15315696 15315696 + Splice_Site SNP G G A TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chrX:15315696G>A c.369C>T c.(367-369)caC>caT p.H123H COAD 23 15315749 15315749 + Missense_Mutation SNP A A G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chrX:15315749A>G c.316T>C c.(316-318)Tgc>Cgc p.C106R COAD 23 15333553 15333553 + Missense_Mutation SNP T T G TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chrX:15333553T>G c.175A>C c.(175-177)Att>Ctt p.I59L COAD 23 15333632 15333633 + Frame_Shift_Ins INS - - A TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chrX:15333632_15333633insA c.95_96insT c.(94-96)ttgfs p.L32fs COAD 23 15333633 15333633 + Frame_Shift_Del DEL A A - TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chrX:15333633delA c.95delT c.(94-96)ttgfs p.L32fs COAD 23 15333660 15333660 + Frame_Shift_Del DEL A A - TCGA-CK-5913-01A-11D-1650-10 TCGA-CK-5913-10A-01D-1650-10 g.chrX:15333660delA c.68delT c.(67-69)ttcfs p.F24fs COAD 23 15333660 15333660 + Frame_Shift_Del DEL A A - TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chrX:15333660delA c.68delT c.(67-69)ttcfs p.F24fs COAD 23 15333694 15333694 + Missense_Mutation SNP T T G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chrX:15333694T>G c.34A>C c.(34-36)Aac>Cac p.N12H COADREAD 23 15301734 15301734 + Missense_Mutation SNP G G T TCGA-AD-6901-01A-11D-1924-10 TCGA-AD-6901-10A-01D-1924-10 g.chrX:15301734G>T c.865C>A c.(865-867)Cag>Aag p.Q289K COADREAD 23 15315696 15315696 + Splice_Site SNP G G A TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chrX:15315696G>A c.369C>T c.(367-369)caC>caT p.H123H COADREAD 23 15315749 15315749 + Missense_Mutation SNP A A G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chrX:15315749A>G c.316T>C c.(316-318)Tgc>Cgc p.C106R COADREAD 23 15333553 15333553 + Missense_Mutation SNP T T G TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chrX:15333553T>G c.175A>C c.(175-177)Att>Ctt p.I59L COADREAD 23 15333632 15333633 + Frame_Shift_Ins INS - - A TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chrX:15333632_15333633insA c.95_96insT c.(94-96)ttgfs p.L32fs COADREAD 23 15333633 15333633 + Frame_Shift_Del DEL A A - TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chrX:15333633delA c.95delT c.(94-96)ttgfs p.L32fs COADREAD 23 15333660 15333660 + Frame_Shift_Del DEL A A - TCGA-CK-5913-01A-11D-1650-10 TCGA-CK-5913-10A-01D-1650-10 g.chrX:15333660delA c.68delT c.(67-69)ttcfs p.F24fs COADREAD 23 15333660 15333660 + Frame_Shift_Del DEL A A - TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chrX:15333660delA c.68delT c.(67-69)ttcfs p.F24fs COADREAD 23 15333668 15333668 + Silent SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chrX:15333668C>T c.60G>A c.(58-60)acG>acA p.T20T COADREAD 23 15333694 15333694 + Missense_Mutation SNP T T G TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chrX:15333694T>G c.34A>C c.(34-36)Aac>Cac p.N12H DLBC 23 15301725 15301725 + Missense_Mutation SNP G G A TCGA-GS-A9TT-01A-11D-A382-10 TCGA-GS-A9TT-10A-01D-A385-10 g.chrX:15301725G>A c.874C>T c.(874-876)Cgc>Tgc p.R292C ESCA 23 15320924 15320924 + Missense_Mutation SNP A A C TCGA-Z6-A8JD-01A-11D-A36J-09 TCGA-Z6-A8JD-10A-01D-A36M-09 g.chrX:15320924A>C c.187T>G c.(187-189)Tgg>Ggg p.W63G GBM 23 15307657 15307657 + Missense_Mutation SNP C C A TCGA-06-0875-01A-01W-0424-08 TCGA-06-0875-10A-01W-0424-08 g.chrX:15307657C>A c.624G>T c.(622-624)agG>agT p.R208S GBMLGG 23 15306083 15306083 + Missense_Mutation SNP C C T TCGA-E1-A7Z3-01A-11D-A34J-08 TCGA-E1-A7Z3-10A-01D-A34M-08 g.chrX:15306083C>T c.767G>A c.(766-768)cGt>cAt p.R256H GBMLGG 23 15307657 15307657 + Missense_Mutation SNP C C A TCGA-06-0875-01A-01W-0424-08 TCGA-06-0875-10A-01W-0424-08 g.chrX:15307657C>A c.624G>T c.(622-624)agG>agT p.R208S KIPAN 23 15320875 15320875 + Missense_Mutation SNP A A G TCGA-BP-4768-01A-01D-1366-10 TCGA-BP-4768-11A-01D-1366-10 g.chrX:15320875A>G c.236T>C c.(235-237)cTg>cCg p.L79P KIRC 23 15320875 15320875 + Missense_Mutation SNP A A G TCGA-BP-4768-01A-01D-1366-10 TCGA-BP-4768-11A-01D-1366-10 g.chrX:15320875A>G c.236T>C c.(235-237)cTg>cCg p.L79P LAML 23 15306084 15306084 + Missense_Mutation SNP G G A TCGA-AB-2923-03A-01W-0745-08 TCGA-AB-2923-11A-01W-0745-08 g.chrX:15306084G>A c.766C>T c.(766-768)Cgt>Tgt p.R256C LGG 23 15306083 15306083 + Missense_Mutation SNP C C T TCGA-E1-A7Z3-01A-11D-A34J-08 TCGA-E1-A7Z3-10A-01D-A34M-08 g.chrX:15306083C>T c.767G>A c.(766-768)cGt>cAt p.R256H LIHC 23 15306022 15306022 + Silent SNP C C T TCGA-G3-AAV4-01A-11D-A382-10 TCGA-G3-AAV4-10A-01D-A385-10 g.chrX:15306022C>T c.828G>A c.(826-828)caG>caA p.Q276Q LUAD 23 15301712 15301712 + Missense_Mutation SNP C C A TCGA-97-A4M7-01A-11D-A24P-08 TCGA-97-A4M7-10A-01D-A24P-08 g.chrX:15301712C>A c.887G>T c.(886-888)cGg>cTg p.R296L LUAD 23 15301747 15301747 + Silent SNP T T A TCGA-44-7670-01A-11D-2063-08 TCGA-44-7670-10A-01D-2063-08 g.chrX:15301747T>A c.852A>T c.(850-852)ccA>ccT p.P284P LUAD 23 15301748 15301748 + Frame_Shift_Del DEL G G - TCGA-55-8299-01A-11D-2284-08 TCGA-55-8299-10B-01D-2323-08 g.chrX:15301748delG c.851delC c.(850-852)ccafs p.P285fs LUAD 23 15306042 15306042 + Missense_Mutation SNP G G T TCGA-99-7458-01A-11D-2036-08 TCGA-99-7458-10A-01D-2036-08 g.chrX:15306042G>T c.808C>A c.(808-810)Cca>Aca p.P270T LUAD 23 15306059 15306059 + Missense_Mutation SNP G G T TCGA-44-6774-01A-21D-1855-08 TCGA-44-6774-10A-01D-1855-08 g.chrX:15306059G>T c.791C>A c.(790-792)gCg>gAg p.A264E LUAD 23 15311352 15311352 + Missense_Mutation SNP C C T TCGA-44-6777-01A-11D-1855-08 TCGA-44-6777-10A-01D-1855-08 g.chrX:15311352C>T c.460G>A c.(460-462)Gga>Aga p.G154R LUAD 23 15315770 15315770 + Missense_Mutation SNP C C A TCGA-MN-A4N5-01A-11D-A24P-08 TCGA-MN-A4N5-10A-01D-A24P-08 g.chrX:15315770C>A c.295G>T c.(295-297)Gtg>Ttg p.V99L LUAD 23 15315773 15315773 + Missense_Mutation SNP G G A TCGA-44-A4SU-01A-11D-A24P-08 TCGA-44-A4SU-10A-01D-A24P-08 g.chrX:15315773G>A c.292C>T c.(292-294)Cgg>Tgg p.R98W LUAD 23 15320871 15320871 + Silent SNP G G T TCGA-55-6985-01A-11D-1945-08 TCGA-55-6985-11A-01D-1945-08 g.chrX:15320871G>T c.240C>A c.(238-240)gcC>gcA p.A80A LUSC 23 15311321 15311321 + Missense_Mutation SNP G G T TCGA-60-2720-01A-01D-1522-08 TCGA-60-2720-11A-01D-1522-08 g.chrX:15311321G>T c.491C>A c.(490-492)gCc>gAc p.A164D LUSC 23 15311360 15311360 + Missense_Mutation SNP A A T TCGA-60-2698-01A-01D-1522-08 TCGA-60-2698-11A-01D-1522-08 g.chrX:15311360A>T c.452T>A c.(451-453)cTg>cAg p.L151Q LUSC 23 15333585 15333585 + Missense_Mutation SNP G G A TCGA-22-4613-01A-01D-1441-08 TCGA-22-4613-11A-01D-1441-08 g.chrX:15333585G>A c.143C>T c.(142-144)gCg>gTg p.A48V OV 23 15306059 15306059 + Missense_Mutation SNP G G T TCGA-13-1408-01A-01W-0490-10 TCGA-13-1408-10A-01W-0491-10 g.chrX:15306059G>T c.791C>A c.(790-792)gCg>gAg p.A264E OV 23 15306080 15306080 + Missense_Mutation SNP C C G TCGA-24-1469-01A-01W-0553-09 TCGA-24-1469-10A-01W-0553-09 g.chrX:15306080C>G c.770G>C c.(769-771)aGa>aCa p.R257T PAAD 23 15301646 15301646 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chrX:15301646C>T c.953G>A c.(952-954)cGa>cAa p.R318Q PAAD 23 15333659 15333660 + Frame_Shift_Ins INS - - A TCGA-FB-AAPS-01A-12D-A397-08 TCGA-FB-AAPS-11A-11D-A39A-08 g.chrX:15333659_15333660insA c.68_69insT c.(67-69)ttcfs p.F23fs PAAD 23 15333659 15333660 + Frame_Shift_Ins INS - - A TCGA-IB-7885-01A-11D-2154-08 TCGA-IB-7885-10A-01D-2154-08 g.chrX:15333659_15333660insA c.68_69insT c.(67-69)ttcfs p.F23fs READ 23 15333668 15333668 + Silent SNP C C T TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chrX:15333668C>T c.60G>A c.(58-60)acG>acA p.T20T SKCM 23 15307707 15307707 + Missense_Mutation SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chrX:15307707C>T c.574G>A c.(574-576)Gag>Aag p.E192K SKCM 23 15311353 15311353 + Silent SNP G G A TCGA-GN-A266-06A-11D-A197-08 TCGA-GN-A266-10A-01D-A199-08 g.chrX:15311353G>A c.459C>T c.(457-459)ttC>ttT p.F153F SKCM 23 15311435 15311435 + Missense_Mutation SNP C C T TCGA-EE-A2M5-06A-12D-A197-08 TCGA-EE-A2M5-10A-01D-A199-08 g.chrX:15311435C>T c.377G>A c.(376-378)gGa>gAa p.G126E SKCM 23 15311436 15311436 + Missense_Mutation SNP C C T TCGA-EE-A2M5-06A-12D-A197-08 TCGA-EE-A2M5-10A-01D-A199-08 g.chrX:15311436C>T c.376G>A c.(376-378)Gga>Aga p.G126R SKCM 23 15332575 15332575 + Intron SNP A A C TCGA-D3-A2JF-06A-11D-A196-08 TCGA-D3-A2JF-10A-01D-A198-08 g.chrX:15332575A>C

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US X 15311338 15311338 single base substitution C G exon_variant BLCA-US X 15311338 15311338 single base substitution C G missense_variant Q137H 411G>C BLCA-US X 15311338 15311338 single base substitution C G missense_variant Q141H 423G>C BLCA-US X 15311338 15311338 single base substitution C G missense_variant Q158H 474G>C BOCA-FR X 15302978 15302978 single base substitution C T intron_variant BOCA-FR X 15315735 15315735 single base substitution G A exon_variant BOCA-FR X 15315735 15315735 single base substitution G A synonymous_variant H110H 330C>T BOCA-FR X 15315735 15315735 single base substitution G A synonymous_variant H89H 267C>T BOCA-FR X 15315735 15315735 single base substitution G A synonymous_variant H93H 279C>T BRCA-EU X 15293209 15293209 single base substitution C T downstream_gene_variant BRCA-EU X 15294403 15294403 single base substitution T C downstream_gene_variant BRCA-EU X 15295650 15295650 insertion of <=200bp - A downstream_gene_variant BRCA-EU X 15296981 15296981 single base substitution G C downstream_gene_variant BRCA-EU X 15297604 15297604 single base substitution T C downstream_gene_variant BRCA-EU X 15298278 15298278 single base substitution A C 3_prime_UTR_variant BRCA-EU X 15298278 15298278 single base substitution A C downstream_gene_variant BRCA-EU X 15298502 15298502 deletion of <=200bp T - 3_prime_UTR_variant BRCA-EU X 15298502 15298502 deletion of <=200bp T - downstream_gene_variant BRCA-EU X 15298665 15298665 single base substitution T G 3_prime_UTR_variant BRCA-EU X 15298665 15298665 single base substitution T G downstream_gene_variant BRCA-EU X 15299051 15299051 single base substitution A G downstream_gene_variant BRCA-EU X 15299051 15299051 single base substitution A G intron_variant BRCA-EU X 15299103 15299103 single base substitution G T downstream_gene_variant BRCA-EU X 15299103 15299103 single base substitution G T intron_variant BRCA-EU X 15299428 15299428 single base substitution G T downstream_gene_variant BRCA-EU X 15299428 15299428 single base substitution G T intron_variant BRCA-EU X 15300319 15300319 deletion of <=200bp A - 3_prime_UTR_variant BRCA-EU X 15300319 15300319 deletion of <=200bp A - downstream_gene_variant BRCA-EU X 15300319 15300319 deletion of <=200bp A - intron_variant BRCA-EU X 15300591 15300591 single base substitution G C 3_prime_UTR_variant BRCA-EU X 15300591 15300591 single base substitution G C downstream_gene_variant BRCA-EU X 15300681 15300681 single base substitution C A 3_prime_UTR_variant BRCA-EU X 15300681 15300681 single base substitution C A downstream_gene_variant BRCA-EU X 15302969 15302969 insertion of <=200bp - A intron_variant BRCA-EU X 15303084 15303084 single base substitution G A intron_variant BRCA-EU X 15304052 15304052 single base substitution G A intron_variant BRCA-EU X 15304175 15304175 single base substitution A G intron_variant BRCA-EU X 15304305 15304305 single base substitution G C intron_variant BRCA-EU X 15305393 15305393 single base substitution C T intron_variant BRCA-EU X 15305739 15305739 single base substitution G A intron_variant BRCA-EU X 15305918 15305918 single base substitution G A intron_variant BRCA-EU X 15306813 15306813 single base substitution C G intron_variant BRCA-EU X 15308047 15308047 single base substitution G A intron_variant BRCA-EU X 15308683 15308686 deletion of <=200bp AATA - intron_variant BRCA-EU X 15310044 15310044 single base substitution C A exon_variant BRCA-EU X 15310044 15310044 single base substitution C A intron_variant BRCA-EU X 15312208 15312208 single base substitution A C intron_variant BRCA-EU X 15312427 15312427 single base substitution G A intron_variant BRCA-EU X 15314490 15314490 single base substitution C A intron_variant BRCA-EU X 15314816 15314816 single base substitution A T intron_variant BRCA-EU X 15317749 15317749 single base substitution A T intron_variant BRCA-EU X 15319459 15319459 single base substitution C G intron_variant BRCA-EU X 15319564 15319564 single base substitution G A intron_variant BRCA-EU X 15320589 15320589 single base substitution C T intron_variant BRCA-EU X 15321461 15321461 single base substitution G A intron_variant BRCA-EU X 15322291 15322291 single base substitution T A intron_variant BRCA-EU X 15322495 15322495 single base substitution G A intron_variant BRCA-EU X 15323144 15323144 single base substitution C A intron_variant BRCA-EU X 15323443 15323443 single base substitution G C intron_variant BRCA-EU X 15324175 15324175 single base substitution A G intron_variant BRCA-EU X 15324312 15324312 single base substitution G C intron_variant BRCA-EU X 15326261 15326261 single base substitution G C intron_variant BRCA-EU X 15326507 15326507 single base substitution G T intron_variant BRCA-EU X 15327295 15327295 single base substitution T A intron_variant BRCA-EU X 15330356 15330356 insertion of <=200bp - A intron_variant BRCA-EU X 15330780 15330780 single base substitution G C intron_variant BRCA-EU X 15334769 15334769 single base substitution G A upstream_gene_variant BRCA-EU X 15335623 15335623 single base substitution G A upstream_gene_variant BRCA-EU X 15335810 15335810 single base substitution C G upstream_gene_variant BRCA-EU X 15336811 15336811 single base substitution C G upstream_gene_variant BRCA-EU X 15337087 15337087 single base substitution T A upstream_gene_variant BRCA-EU X 15337392 15337392 single base substitution G C upstream_gene_variant BRCA-EU X 15337729 15337729 single base substitution A C upstream_gene_variant BRCA-EU X 15338553 15338556 deletion of <=200bp ATAA - upstream_gene_variant BRCA-FR X 15294748 15294748 single base substitution T A downstream_gene_variant BRCA-FR X 15312427 15312427 single base substitution G A intron_variant BRCA-FR X 15322291 15322291 single base substitution T A intron_variant BRCA-FR X 15332134 15332134 single base substitution G C intron_variant BRCA-FR X 15334962 15334962 single base substitution C A upstream_gene_variant BRCA-FR X 15335623 15335623 single base substitution G A upstream_gene_variant BRCA-FR X 15335810 15335810 single base substitution C G upstream_gene_variant BRCA-UK X 15300681 15300681 single base substitution C A 3_prime_UTR_variant BRCA-UK X 15300681 15300681 single base substitution C A downstream_gene_variant BRCA-UK X 15326261 15326261 single base substitution G C intron_variant BRCA-US X 15306047 15306047 single base substitution G A 3_prime_UTR_variant BRCA-US X 15306047 15306047 single base substitution G A missense_variant A247V 740C>T BRCA-US X 15306047 15306047 single base substitution G A missense_variant A251V 752C>T BRCA-US X 15306047 15306047 single base substitution G A missense_variant A268V 803C>T BRCA-US X 15333633 15333633 deletion of <=200bp A - exon_variant BRCA-US X 15333633 15333633 deletion of <=200bp A - frameshift_variant L32 BRCA-US X 15333633 15333633 deletion of <=200bp A - upstream_gene_variant BTCA-JP X 15332622 15332622 single base substitution C A 5_prime_UTR_variant BTCA-JP X 15332622 15332622 single base substitution C A intron_variant CLLE-ES X 15295257 15295257 single base substitution G T downstream_gene_variant CLLE-ES X 15311191 15311191 single base substitution A G intron_variant CLLE-ES X 15328365 15328365 single base substitution C A intron_variant CLLE-ES X 15328668 15328668 single base substitution A G intron_variant COAD-US X 15301662 15301662 single base substitution G T 3_prime_UTR_variant COAD-US X 15301662 15301662 single base substitution G T missense_variant P292T 874C>A COAD-US X 15301662 15301662 single base substitution G T missense_variant P296T 886C>A COAD-US X 15301662 15301662 single base substitution G T missense_variant P313T 937C>A COAD-US X 15301734 15301734 single base substitution G T 3_prime_UTR_variant COAD-US X 15301734 15301734 single base substitution G T missense_variant Q268K 802C>A COAD-US X 15301734 15301734 single base substitution G T missense_variant Q272K 814C>A COAD-US X 15301734 15301734 single base substitution G T missense_variant Q289K 865C>A COAD-US X 15315749 15315749 single base substitution A G exon_variant COAD-US X 15315749 15315749 single base substitution A G missense_variant C106R 316T>C COAD-US X 15315749 15315749 single base substitution A G missense_variant C85R 253T>C COAD-US X 15315749 15315749 single base substitution A G missense_variant C89R 265T>C COAD-US X 15332558 15332558 single base substitution A G intron_variant COAD-US X 15332558 15332558 single base substitution A G synonymous_variant R17R 51T>C COAD-US X 15333553 15333553 single base substitution T G exon_variant COAD-US X 15333553 15333553 single base substitution T G missense_variant I59L 175A>C COAD-US X 15333553 15333553 single base substitution T G upstream_gene_variant COAD-US X 15333632 15333632 insertion of <=200bp - A exon_variant COAD-US X 15333632 15333632 insertion of <=200bp - A frameshift_variant L32L? COAD-US X 15333632 15333632 insertion of <=200bp - A upstream_gene_variant COAD-US X 15333633 15333633 deletion of <=200bp A - exon_variant COAD-US X 15333633 15333633 deletion of <=200bp A - frameshift_variant L32 COAD-US X 15333633 15333633 deletion of <=200bp A - upstream_gene_variant COAD-US X 15333660 15333660 deletion of <=200bp A - exon_variant COAD-US X 15333660 15333660 deletion of <=200bp A - frameshift_variant F23 COAD-US X 15333660 15333660 deletion of <=200bp A - upstream_gene_variant COAD-US X 15333694 15333694 single base substitution T G exon_variant COAD-US X 15333694 15333694 single base substitution T G missense_variant N12H 34A>C COAD-US X 15333694 15333694 single base substitution T G upstream_gene_variant COCA-CN X 15301651 15301651 single base substitution G A 3_prime_UTR_variant COCA-CN X 15301651 15301651 single base substitution G A synonymous_variant L295L 885C>T COCA-CN X 15301651 15301651 single base substitution G A synonymous_variant L299L 897C>T COCA-CN X 15301651 15301651 single base substitution G A synonymous_variant L316L 948C>T COCA-CN X 15316231 15316231 single base substitution G A intron_variant COCA-CN X 15332531 15332531 single base substitution C A intron_variant COCA-CN X 15332531 15332531 single base substitution C A missense_variant E26D 78G>T ESCA-CN X 15332471 15332471 single base substitution A T intron_variant GBM-US X 15307657 15307657 single base substitution C A 3_prime_UTR_variant GBM-US X 15307657 15307657 single base substitution C A missense_variant R187S 561G>T GBM-US X 15307657 15307657 single base substitution C A missense_variant R191S 573G>T GBM-US X 15307657 15307657 single base substitution C A missense_variant R208S 624G>T KIRC-US X 15320875 15320875 single base substitution A G exon_variant KIRC-US X 15320875 15320875 single base substitution A G missense_variant L58P 173T>C KIRC-US X 15320875 15320875 single base substitution A G missense_variant L79P 236T>C LICA-FR X 15313581 15313581 single base substitution T A intron_variant LICA-FR X 15327858 15327858 single base substitution G A intron_variant LICA-FR X 15333348 15333348 single base substitution C T intron_variant LICA-FR X 15333348 15333348 single base substitution C T upstream_gene_variant LINC-JP X 15307672 15307672 single base substitution G A 3_prime_UTR_variant LINC-JP X 15307672 15307672 single base substitution G A synonymous_variant A182A 546C>T LINC-JP X 15307672 15307672 single base substitution G A synonymous_variant A186A 558C>T LINC-JP X 15307672 15307672 single base substitution G A synonymous_variant A203A 609C>T LINC-JP X 15309857 15309857 single base substitution T A intron_variant LINC-JP X 15320971 15320971 single base substitution C A intron_variant LINC-JP X 15324138 15324138 single base substitution C A intron_variant LINC-JP X 15324145 15324145 single base substitution C T intron_variant LIRI-JP X 15295894 15295894 single base substitution C T downstream_gene_variant LIRI-JP X 15303954 15303954 single base substitution C A intron_variant LIRI-JP X 15304214 15304214 single base substitution C T intron_variant LIRI-JP X 15306083 15306083 single base substitution C T 3_prime_UTR_variant LIRI-JP X 15306083 15306083 single base substitution C T missense_variant R235H 704G>A LIRI-JP X 15306083 15306083 single base substitution C T missense_variant R239H 716G>A LIRI-JP X 15306083 15306083 single base substitution C T missense_variant R256H 767G>A LIRI-JP X 15306541 15306541 single base substitution C A intron_variant LIRI-JP X 15307708 15307708 single base substitution A G 3_prime_UTR_variant LIRI-JP X 15307708 15307708 single base substitution A G synonymous_variant H170H 510T>C LIRI-JP X 15307708 15307708 single base substitution A G synonymous_variant H174H 522T>C LIRI-JP X 15307708 15307708 single base substitution A G synonymous_variant H191H 573T>C LIRI-JP X 15308194 15308194 single base substitution T C intron_variant LIRI-JP X 15312519 15312519 single base substitution G A intron_variant LIRI-JP X 15313011 15313011 single base substitution A T intron_variant LIRI-JP X 15314530 15314530 deletion of <=200bp T - intron_variant LIRI-JP X 15317028 15317028 single base substitution C T intron_variant LIRI-JP X 15317809 15317809 single base substitution C T intron_variant LIRI-JP X 15319287 15319287 single base substitution G A intron_variant LIRI-JP X 15319711 15319711 single base substitution A G intron_variant LIRI-JP X 15320616 15320616 single base substitution G T intron_variant LIRI-JP X 15321092 15321092 single base substitution A G intron_variant LIRI-JP X 15321708 15321708 deletion of <=200bp T - intron_variant LIRI-JP X 15327704 15327704 single base substitution A T intron_variant LIRI-JP X 15327917 15327917 single base substitution A G intron_variant LIRI-JP X 15328243 15328243 deletion of <=200bp A - intron_variant LIRI-JP X 15332685 15332685 single base substitution G A intron_variant LIRI-JP X 15332685 15332685 single base substitution G A upstream_gene_variant LIRI-JP X 15337280 15337280 single base substitution T C upstream_gene_variant LIRI-JP X 15337343 15337343 single base substitution T C upstream_gene_variant LIRI-JP X 15338691 15338691 single base substitution T G upstream_gene_variant LUSC-KR X 15293308 15293308 single base substitution C A downstream_gene_variant LUSC-KR X 15294992 15294992 single base substitution G C downstream_gene_variant LUSC-KR X 15297118 15297118 single base substitution C A downstream_gene_variant LUSC-KR X 15303382 15303382 single base substitution C A intron_variant LUSC-KR X 15303755 15303755 single base substitution C G intron_variant LUSC-KR X 15307574 15307574 single base substitution G C intron_variant LUSC-KR X 15313289 15313289 single base substitution C A intron_variant LUSC-KR X 15330614 15330614 single base substitution G T intron_variant LUSC-KR X 15332469 15332469 single base substitution G T intron_variant LUSC-KR X 15334483 15334483 single base substitution C A upstream_gene_variant LUSC-US X 15311321 15311321 single base substitution G T exon_variant LUSC-US X 15311321 15311321 single base substitution G T missense_variant A143D 428C>A LUSC-US X 15311321 15311321 single base substitution G T missense_variant A147D 440C>A LUSC-US X 15311321 15311321 single base substitution G T missense_variant A164D 491C>A LUSC-US X 15311360 15311360 single base substitution A T exon_variant LUSC-US X 15311360 15311360 single base substitution A T missense_variant L130Q 389T>A LUSC-US X 15311360 15311360 single base substitution A T missense_variant L134Q 401T>A LUSC-US X 15311360 15311360 single base substitution A T missense_variant L151Q 452T>A LUSC-US X 15333585 15333585 single base substitution G A exon_variant LUSC-US X 15333585 15333585 single base substitution G A missense_variant A48V 143C>T LUSC-US X 15333585 15333585 single base substitution G A upstream_gene_variant MALY-DE X 15293376 15293376 single base substitution C G downstream_gene_variant MALY-DE X 15299191 15299191 single base substitution G A downstream_gene_variant MALY-DE X 15299191 15299191 single base substitution G A intron_variant MALY-DE X 15300319 15300319 deletion of <=200bp A - 3_prime_UTR_variant MALY-DE X 15300319 15300319 deletion of <=200bp A - downstream_gene_variant MALY-DE X 15300319 15300319 deletion of <=200bp A - intron_variant MALY-DE X 15302084 15302084 single base substitution G A intron_variant MALY-DE X 15303552 15303552 single base substitution C T intron_variant MALY-DE X 15306388 15306388 single base substitution G T intron_variant MALY-DE X 15306512 15306512 single base substitution A C intron_variant MALY-DE X 15313584 15313584 single base substitution G A intron_variant MALY-DE X 15323402 15323402 single base substitution G A intron_variant MALY-DE X 15324826 15324826 insertion of <=200bp - AAC intron_variant MALY-DE X 15324826 15324828 deletion of <=200bp AAC - intron_variant MALY-DE X 15325462 15325462 single base substitution C T intron_variant MELA-AU X 15293319 15293319 single base substitution G A downstream_gene_variant MELA-AU X 15295330 15295330 single base substitution C T downstream_gene_variant MELA-AU X 15295993 15295994 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU X 15296169 15296169 single base substitution C T downstream_gene_variant MELA-AU X 15296534 15296534 single base substitution G A downstream_gene_variant MELA-AU X 15298268 15298268 single base substitution C T 3_prime_UTR_variant MELA-AU X 15298268 15298268 single base substitution C T downstream_gene_variant MELA-AU X 15298833 15298833 single base substitution G A downstream_gene_variant MELA-AU X 15298833 15298833 single base substitution G A intron_variant MELA-AU X 15300292 15300292 single base substitution G A 3_prime_UTR_variant MELA-AU X 15300292 15300292 single base substitution G A downstream_gene_variant MELA-AU X 15300292 15300292 single base substitution G A intron_variant MELA-AU X 15300507 15300507 single base substitution A C 3_prime_UTR_variant MELA-AU X 15300507 15300507 single base substitution A C downstream_gene_variant MELA-AU X 15300666 15300666 single base substitution G A 3_prime_UTR_variant MELA-AU X 15300666 15300666 single base substitution G A downstream_gene_variant MELA-AU X 15301170 15301170 single base substitution G A 3_prime_UTR_variant MELA-AU X 15301170 15301170 single base substitution G A downstream_gene_variant MELA-AU X 15301245 15301245 single base substitution A T 3_prime_UTR_variant MELA-AU X 15301245 15301245 single base substitution A T downstream_gene_variant MELA-AU X 15301731 15301731 single base substitution G A 3_prime_UTR_variant MELA-AU X 15301731 15301731 single base substitution G A missense_variant L269F 805C>T MELA-AU X 15301731 15301731 single base substitution G A missense_variant L273F 817C>T MELA-AU X 15301731 15301731 single base substitution G A missense_variant L290F 868C>T MELA-AU X 15302496 15302496 single base substitution G A intron_variant MELA-AU X 15302896 15302896 single base substitution C T intron_variant MELA-AU X 15303141 15303141 single base substitution A T intron_variant MELA-AU X 15303694 15303694 single base substitution G A intron_variant MELA-AU X 15303730 15303730 single base substitution G A intron_variant MELA-AU X 15303940 15303940 single base substitution A G intron_variant MELA-AU X 15304287 15304287 single base substitution G A intron_variant MELA-AU X 15304584 15304584 single base substitution C T intron_variant MELA-AU X 15304657 15304657 single base substitution C A intron_variant MELA-AU X 15305078 15305078 single base substitution G A intron_variant MELA-AU X 15305330 15305330 single base substitution T C intron_variant MELA-AU X 15305481 15305481 single base substitution C T intron_variant MELA-AU X 15305483 15305483 single base substitution C A intron_variant MELA-AU X 15305811 15305811 single base substitution C T intron_variant MELA-AU X 15307436 15307436 single base substitution G A intron_variant MELA-AU X 15309002 15309002 single base substitution C T intron_variant MELA-AU X 15310226 15310226 single base substitution G A intron_variant MELA-AU X 15310903 15310903 single base substitution G A intron_variant MELA-AU X 15310929 15310929 single base substitution G A intron_variant MELA-AU X 15311435 15311436 multiple base substitution (>=2bp and <=200bp) CC TT exon_variant MELA-AU X 15311435 15311436 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant G105K 313GG>AA MELA-AU X 15311435 15311436 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant G109K 325GG>AA MELA-AU X 15311435 15311436 multiple base substitution (>=2bp and <=200bp) CC TT missense_variant G126K 376GG>AA MELA-AU X 15312887 15312887 single base substitution G A intron_variant MELA-AU X 15313891 15313891 single base substitution C T intron_variant MELA-AU X 15314285 15314285 single base substitution C T intron_variant MELA-AU X 15314315 15314315 single base substitution G A intron_variant MELA-AU X 15314368 15314368 single base substitution C T intron_variant MELA-AU X 15314389 15314389 single base substitution G A intron_variant MELA-AU X 15314690 15314690 single base substitution C T intron_variant MELA-AU X 15315199 15315199 single base substitution A G intron_variant MELA-AU X 15315206 15315206 single base substitution G A intron_variant MELA-AU X 15317610 15317610 single base substitution C T intron_variant MELA-AU X 15319654 15319654 single base substitution G A intron_variant MELA-AU X 15319672 15319672 single base substitution A G intron_variant MELA-AU X 15320585 15320585 single base substitution C T intron_variant MELA-AU X 15320680 15320680 single base substitution G A intron_variant MELA-AU X 15320885 15320885 single base substitution C G exon_variant MELA-AU X 15320885 15320885 single base substitution C G missense_variant G55R 163G>C MELA-AU X 15320885 15320885 single base substitution C G missense_variant G76R 226G>C MELA-AU X 15322038 15322038 single base substitution A G intron_variant MELA-AU X 15322526 15322526 single base substitution G A intron_variant MELA-AU X 15323058 15323058 single base substitution G A intron_variant MELA-AU X 15323821 15323821 single base substitution G A intron_variant MELA-AU X 15324150 15324151 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU X 15324457 15324457 single base substitution T G intron_variant MELA-AU X 15325137 15325137 single base substitution C G intron_variant MELA-AU X 15326174 15326174 single base substitution T C intron_variant MELA-AU X 15326581 15326581 single base substitution T C intron_variant MELA-AU X 15326883 15326883 single base substitution C T intron_variant MELA-AU X 15327137 15327137 single base substitution C A intron_variant MELA-AU X 15327235 15327235 single base substitution C T intron_variant MELA-AU X 15327973 15327973 single base substitution C T intron_variant MELA-AU X 15331637 15331637 single base substitution A T intron_variant MELA-AU X 15332084 15332084 single base substitution G A intron_variant MELA-AU X 15332209 15332209 single base substitution T C intron_variant MELA-AU X 15333379 15333379 single base substitution C T intron_variant MELA-AU X 15333379 15333379 single base substitution C T upstream_gene_variant MELA-AU X 15334364 15334364 single base substitution A T upstream_gene_variant MELA-AU X 15334624 15334624 single base substitution T A upstream_gene_variant MELA-AU X 15334732 15334732 single base substitution G A upstream_gene_variant MELA-AU X 15334866 15334866 single base substitution G A upstream_gene_variant MELA-AU X 15335533 15335533 single base substitution C T upstream_gene_variant MELA-AU X 15337101 15337101 single base substitution G A upstream_gene_variant MELA-AU X 15338138 15338138 single base substitution A C upstream_gene_variant ORCA-IN X 15301255 15301255 single base substitution T G 3_prime_UTR_variant ORCA-IN X 15301255 15301255 single base substitution T G downstream_gene_variant OV-AU X 15306899 15306899 single base substitution C T intron_variant OV-AU X 15316912 15316912 single base substitution G A intron_variant OV-AU X 15320789 15320789 single base substitution A T intron_variant OV-AU X 15325097 15325097 single base substitution C A intron_variant OV-AU X 15327481 15327481 single base substitution T A intron_variant OV-AU X 15328908 15328908 single base substitution G A intron_variant OV-US X 15306080 15306080 single base substitution C G 3_prime_UTR_variant OV-US X 15306080 15306080 single base substitution C G missense_variant R236T 707G>C OV-US X 15306080 15306080 single base substitution C G missense_variant R240T 719G>C OV-US X 15306080 15306080 single base substitution C G missense_variant R257T 770G>C PACA-AU X 15297617 15297617 single base substitution G A downstream_gene_variant PACA-AU X 15299165 15299165 single base substitution A G downstream_gene_variant PACA-AU X 15299165 15299165 single base substitution A G intron_variant PACA-AU X 15300730 15300730 single base substitution G C 3_prime_UTR_variant PACA-AU X 15300730 15300730 single base substitution G C downstream_gene_variant PACA-AU X 15304052 15304052 single base substitution G A intron_variant PACA-AU X 15306963 15306963 single base substitution C T intron_variant PACA-AU X 15307786 15307786 single base substitution T G intron_variant PACA-AU X 15313234 15313234 single base substitution G A intron_variant PACA-AU X 15314326 15314326 single base substitution G A intron_variant PACA-AU X 15314754 15314754 single base substitution A G intron_variant PACA-AU X 15316882 15316882 single base substitution C A intron_variant PACA-AU X 15321029 15321029 single base substitution A G intron_variant PACA-AU X 15323913 15323913 single base substitution G A intron_variant PACA-AU X 15325808 15325808 single base substitution G T intron_variant PACA-AU X 15327298 15327298 single base substitution C A intron_variant PACA-AU X 15330363 15330363 single base substitution A T intron_variant PACA-AU X 15333731 15333731 deletion of <=200bp G - 5_prime_UTR_variant PACA-AU X 15333731 15333731 deletion of <=200bp G - upstream_gene_variant PACA-AU X 15334252 15334252 single base substitution G T upstream_gene_variant PACA-CA X 15293209 15293209 single base substitution C T downstream_gene_variant PACA-CA X 15300579 15300579 insertion of <=200bp - A 3_prime_UTR_variant PACA-CA X 15300579 15300579 insertion of <=200bp - A downstream_gene_variant PACA-CA X 15301496 15301496 single base substitution G T 3_prime_UTR_variant PACA-CA X 15301496 15301496 single base substitution G T downstream_gene_variant PACA-CA X 15302385 15302385 single base substitution A G intron_variant PACA-CA X 15306261 15306261 single base substitution A G intron_variant PACA-CA X 15309822 15309822 single base substitution C T intron_variant PACA-CA X 15310592 15310592 single base substitution C T intron_variant PACA-CA X 15312837 15312837 single base substitution G T intron_variant PACA-CA X 15313998 15313998 single base substitution A T intron_variant PACA-CA X 15316999 15317010 deletion of <=200bp GTCTCTGAAGTC - intron_variant PACA-CA X 15318773 15318773 single base substitution T G intron_variant PACA-CA X 15331377 15331377 single base substitution C T intron_variant PACA-CA X 15331591 15331591 single base substitution A T intron_variant PACA-CA X 15333970 15333970 single base substitution C T upstream_gene_variant PACA-CA X 15334699 15334699 single base substitution C T upstream_gene_variant PACA-CA X 15334867 15334867 single base substitution G C upstream_gene_variant PAEN-IT X 15327230 15327230 single base substitution G A intron_variant PBCA-DE X 15293209 15293209 single base substitution C T downstream_gene_variant PBCA-DE X 15293405 15293405 single base substitution C T downstream_gene_variant PBCA-DE X 15294851 15294851 single base substitution G A downstream_gene_variant PBCA-DE X 15301734 15301734 single base substitution G T 3_prime_UTR_variant PBCA-DE X 15301734 15301734 single base substitution G T missense_variant Q268K 802C>A PBCA-DE X 15301734 15301734 single base substitution G T missense_variant Q272K 814C>A PBCA-DE X 15301734 15301734 single base substitution G T missense_variant Q289K 865C>A PBCA-DE X 15304129 15304131 deletion of <=200bp AAT - intron_variant PBCA-DE X 15312244 15312244 single base substitution G T intron_variant PBCA-DE X 15315351 15315351 single base substitution C T intron_variant PBCA-DE X 15322600 15322600 deletion of <=200bp T - intron_variant PBCA-DE X 15328898 15328898 single base substitution T A intron_variant PBCA-DE X 15329783 15329783 deletion of <=200bp T - intron_variant PBCA-DE X 15332545 15332545 single base substitution C T intron_variant PBCA-DE X 15332545 15332545 single base substitution C T missense_variant G22R 64G>A PBCA-DE X 15333390 15333390 single base substitution T A intron_variant PBCA-DE X 15333390 15333390 single base substitution T A upstream_gene_variant PBCA-DE X 15337118 15337127 deletion of <=200bp ATATATAAAT - upstream_gene_variant PBCA-DE X 15337126 15337126 single base substitution A G upstream_gene_variant PBCA-DE X 15337558 15337558 single base substitution A T upstream_gene_variant PRAD-CA X 15307770 15307770 single base substitution C A intron_variant PRAD-CA X 15321131 15321131 single base substitution C T intron_variant PRAD-CA X 15331895 15331895 single base substitution C T intron_variant PRAD-UK X 15304616 15304616 single base substitution G A intron_variant PRAD-UK X 15309429 15309429 single base substitution C T intron_variant PRAD-UK X 15323855 15323855 single base substitution T A intron_variant PRAD-UK X 15329363 15329372 deletion of <=200bp TGAGCTGTGT - intron_variant PRAD-UK X 15330866 15330866 single base substitution G T intron_variant READ-US X 15301633 15301633 single base substitution G T 3_prime_UTR_variant READ-US X 15301633 15301633 single base substitution G T stop_gained Y301* 903C>A READ-US X 15301633 15301633 single base substitution G T stop_gained Y305* 915C>A READ-US X 15301633 15301633 single base substitution G T stop_gained Y322* 966C>A RECA-EU X 15296498 15296498 single base substitution C A downstream_gene_variant SKCA-BR X 15301095 15301095 single base substitution T A 3_prime_UTR_variant SKCA-BR X 15301095 15301095 single base substitution T A downstream_gene_variant SKCA-BR X 15302962 15302962 single base substitution C T intron_variant SKCA-BR X 15302999 15302999 single base substitution C T intron_variant SKCA-BR X 15312143 15312143 single base substitution T C intron_variant SKCA-BR X 15312201 15312201 single base substitution G A intron_variant SKCA-BR X 15312202 15312202 single base substitution G A intron_variant SKCA-BR X 15323180 15323180 single base substitution A C intron_variant SKCA-BR X 15330559 15330559 single base substitution C A intron_variant SKCA-BR X 15332451 15332451 insertion of <=200bp - CT intron_variant SKCA-BR X 15334529 15334529 insertion of <=200bp - CA upstream_gene_variant SKCA-BR X 15336508 15336508 single base substitution G A upstream_gene_variant SKCM-US X 15307707 15307707 single base substitution C T 3_prime_UTR_variant SKCM-US X 15307707 15307707 single base substitution C T missense_variant E171K 511G>A SKCM-US X 15307707 15307707 single base substitution C T missense_variant E175K 523G>A SKCM-US X 15307707 15307707 single base substitution C T missense_variant E192K 574G>A SKCM-US X 15311353 15311353 single base substitution G A exon_variant SKCM-US X 15311353 15311353 single base substitution G A synonymous_variant F132F 396C>T SKCM-US X 15311353 15311353 single base substitution G A synonymous_variant F136F 408C>T SKCM-US X 15311353 15311353 single base substitution G A synonymous_variant F153F 459C>T STAD-US X 15306011 15306011 single base substitution A G 3_prime_UTR_variant STAD-US X 15306011 15306011 single base substitution A G missense_variant L259P 776T>C STAD-US X 15306011 15306011 single base substitution A G missense_variant L263P 788T>C STAD-US X 15306011 15306011 single base substitution A G missense_variant L280P 839T>C STAD-US X 15306058 15306058 single base substitution C T 3_prime_UTR_variant STAD-US X 15306058 15306058 single base substitution C T synonymous_variant A243A 729G>A STAD-US X 15306058 15306058 single base substitution C T synonymous_variant A247A 741G>A STAD-US X 15306058 15306058 single base substitution C T synonymous_variant A264A 792G>A STAD-US X 15306176 15306176 single base substitution C T 3_prime_UTR_variant STAD-US X 15306176 15306176 single base substitution C T missense_variant G204D 611G>A STAD-US X 15306176 15306176 single base substitution C T missense_variant G208D 623G>A STAD-US X 15306176 15306176 single base substitution C T missense_variant G225D 674G>A STAD-US X 15307687 15307687 single base substitution A G 3_prime_UTR_variant STAD-US X 15307687 15307687 single base substitution A G synonymous_variant T177T 531T>C STAD-US X 15307687 15307687 single base substitution A G synonymous_variant T181T 543T>C STAD-US X 15307687 15307687 single base substitution A G synonymous_variant T198T 594T>C STAD-US X 15311390 15311390 single base substitution C T exon_variant STAD-US X 15311390 15311390 single base substitution C T missense_variant S120N 359G>A STAD-US X 15311390 15311390 single base substitution C T missense_variant S124N 371G>A STAD-US X 15311390 15311390 single base substitution C T missense_variant S141N 422G>A STAD-US X 15315756 15315756 single base substitution G T exon_variant STAD-US X 15315756 15315756 single base substitution G T missense_variant H103Q 309C>A STAD-US X 15315756 15315756 single base substitution G T missense_variant H82Q 246C>A STAD-US X 15315756 15315756 single base substitution G T splice_region_variant STAD-US X 15333600 15333600 single base substitution C T exon_variant STAD-US X 15333600 15333600 single base substitution C T missense_variant G43E 128G>A STAD-US X 15333600 15333600 single base substitution C T upstream_gene_variant UCEC-US X 15306046 15306046 single base substitution C T 3_prime_UTR_variant UCEC-US X 15306046 15306046 single base substitution C T synonymous_variant A247A 741G>A UCEC-US X 15306046 15306046 single base substitution C T synonymous_variant A251A 753G>A UCEC-US X 15306046 15306046 single base substitution C T synonymous_variant A268A 804G>A UCEC-US X 15306080 15306080 single base substitution C A 3_prime_UTR_variant UCEC-US X 15306080 15306080 single base substitution C A missense_variant R236I 707G>T UCEC-US X 15306080 15306080 single base substitution C A missense_variant R240I 719G>T UCEC-US X 15306080 15306080 single base substitution C A missense_variant R257I 770G>T UCEC-US X 15306084 15306084 single base substitution G A 3_prime_UTR_variant UCEC-US X 15306084 15306084 single base substitution G A missense_variant R235C 703C>T UCEC-US X 15306084 15306084 single base substitution G A missense_variant R239C 715C>T UCEC-US X 15306084 15306084 single base substitution G A missense_variant R256C 766C>T UCEC-US X 15307633 15307633 single base substitution T G 3_prime_UTR_variant UCEC-US X 15307633 15307633 single base substitution T G synonymous_variant L195L 585A>C UCEC-US X 15307633 15307633 single base substitution T G synonymous_variant L199L 597A>C UCEC-US X 15307633 15307633 single base substitution T G synonymous_variant L216L 648A>C UCEC-US X 15307642 15307642 single base substitution C A 3_prime_UTR_variant UCEC-US X 15307642 15307642 single base substitution C A missense_variant K192N 576G>T UCEC-US X 15307642 15307642 single base substitution C A missense_variant K196N 588G>T UCEC-US X 15307642 15307642 single base substitution C A missense_variant K213N 639G>T UCEC-US X 15311417 15311417 single base substitution G A exon_variant UCEC-US X 15311417 15311417 single base substitution G A missense_variant A111V 332C>T UCEC-US X 15311417 15311417 single base substitution G A missense_variant A115V 344C>T UCEC-US X 15311417 15311417 single base substitution G A missense_variant A132V 395C>T UCEC-US X 15311420 15311420 single base substitution C T exon_variant UCEC-US X 15311420 15311420 single base substitution C T missense_variant G110E 329G>A UCEC-US X 15311420 15311420 single base substitution C T missense_variant G114E 341G>A UCEC-US X 15311420 15311420 single base substitution C T missense_variant G131E 392G>A UCEC-US X 15315696 15315696 single base substitution G A splice_region_variant UCEC-US X 15315763 15315763 single base substitution G T exon_variant UCEC-US X 15315763 15315763 single base substitution G T intron_variant UCEC-US X 15315763 15315763 single base substitution G T missense_variant S101Y 302C>A UCEC-US X 15315763 15315763 single base substitution G T missense_variant S80Y 239C>A UCEC-US X 15320904 15320904 single base substitution A C exon_variant UCEC-US X 15320904 15320904 single base substitution A C synonymous_variant L48L 144T>G UCEC-US X 15320904 15320904 single base substitution A C synonymous_variant L69L 207T>G UCEC-US X 15332526 15332526 single base substitution G T intron_variant UCEC-US X 15332526 15332526 single base substitution G T missense_variant S28Y 83C>A UCEC-US X 15333553 15333553 single base substitution T C exon_variant UCEC-US X 15333553 15333553 single base substitution T C missense_variant I59V 175A>G UCEC-US X 15333553 15333553 single base substitution T C upstream_gene_variant UCEC-US X 15333571 15333571 single base substitution C A exon_variant UCEC-US X 15333571 15333571 single base substitution C A stop_gained E53* 157G>T UCEC-US X 15333571 15333571 single base substitution C A upstream_gene_variant UCEC-US X 15333608 15333608 single base substitution G A exon_variant UCEC-US X 15333608 15333608 single base substitution G A synonymous_variant I40I 120C>T UCEC-US X 15333608 15333608 single base substitution G A upstream_gene_variant UCEC-US X 15333674 15333674 single base substitution A G exon_variant UCEC-US X 15333674 15333674 single base substitution A G synonymous_variant F18F 54T>C UCEC-US X 15333674 15333674 single base substitution A G upstream_gene_variant UCEC-US X 15333676 15333676 single base substitution A G exon_variant UCEC-US X 15333676 15333676 single base substitution A G missense_variant F18L 52T>C UCEC-US X 15333676 15333676 single base substitution A G upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand 10-P4110 COSM4589292 c.257C>T p.A86V Substitution - Missense 23:15302732-15302732 - CSCC-49-T COSM4496340 c.472C>T p.Q158* Substitution - Nonsense 23:15293218-15293218 - RK225_C01 COSM4780278 c.573T>C p.H191H Substitution - coding silent 23:15289586-15289586 - I2L-P7-Tumor-Organoid COSM5367453 c.550G>T p.A184S Substitution - Missense 23:15289609-15289609 - TCGA-A6-5665-01 COSM1466486 c.95_96insT p.L32fs*14 Insertion - Frameshift 23:15315510-15315511 - TCGA-06-0875 COSM2152027 c.624G>T p.R208S Substitution - Missense 23:15289535-15289535 - T368 COSM4663625 c.341C>T p.A114V Substitution - Missense 23:15297602-15297602 - Gp5D COSM3236209 c.414T>C p.A138A Substitution - coding silent 23:15293276-15293276 - RD COSM4989700 c.461G>A p.G154E Substitution - Missense 23:15293229-15293229 - Pat_24_A COSM5877360 c.958C>T p.L320F Substitution - Missense 23:15283519-15283519 - TCGA-AX-A05Z-01 COSM1117541 c.770G>T p.R257I Substitution - Missense 23:15287958-15287958 - TCGA-AB-2923-03 COSM1117542 c.766C>T p.R256C Substitution - Missense 23:15287962-15287962 - HCC2218 COSM32274 c.936_941delGCCAGA p.P313_E314del Deletion - In frame 23:15283536-15283541 - TCGA-AX-A05Z-01 COSM1117803 c.175A>G p.I59V Substitution - Missense 23:15315431-15315431 - CSCC-10-T COSM4566036 c.291_292CC>TT p.R98W Substitution - Missense 23:15297651-15297652 - MZ7-mel COSM24383 c.367C>T p.H123Y Substitution - Missense 23:15297576-15297576 - TCGA-CD-5813-01 COSM4107916 c.309C>A p.H103Q Substitution - Missense 23:15297634-15297634 - TCGA-AG-3891-01 COSM1466486 c.95_96insT p.L32fs*14 Insertion - Frameshift 23:15315510-15315511 - 61 COSM5742205 c.370-2A>G p.? Unknown 23:15293322-15293322 - TCGA-DK-A3WW-01 COSM3800483 c.474G>C p.Q158H Substitution - Missense 23:15293216-15293216 - TCGA-B5-A0JY-01 COSM1117566 c.395C>T p.A132V Substitution - Missense 23:15293295-15293295 - TCGA-GN-A266-06 COSM3559574 c.459C>T p.F153F Substitution - coding silent 23:15293231-15293231 - ESO-708 COSM1245531 c.820G>A p.V274M Substitution - Missense 23:15287908-15287908 - TCGA-DI-A0WH-01 COSM1117565 c.492C>A p.A164A Substitution - coding silent 23:15293198-15293198 - TCGA-BS-A0UV-01 COSM1117805 c.120C>T p.I40I Substitution - coding silent 23:15315486-15315486 - TCGA-22-4613-01 COSM755700 c.143C>T p.A48V Substitution - Missense 23:15315463-15315463 - T2269 COSM3235868 c.949G>A p.E317K Substitution - Missense 23:15283528-15283528 - 2250172 COSM5030163 c.330C>T p.H110H Substitution - coding silent 23:15297613-15297613 - TCGA-AX-A0J0-01 COSM1117563 c.648A>C p.L216L Substitution - coding silent 23:15289511-15289511 - TCGA-AZ-4315-01 COSM1466485 c.175A>C p.I59L Substitution - Missense 23:15315431-15315431 - TCGA-60-2720-01 COSM755742 c.491C>A p.A164D Substitution - Missense 23:15293199-15293199 - HCC2218 COSM24381 c.940_945delGAGCCA p.E314_L316>L Deletion - In frame 23:15283532-15283537 - KM12 COSM1466487 c.95delT p.L32fs*4 Deletion - Frameshift 23:15315511-15315511 - TCGA-AG-A002-01 COSM259521 c.60G>A p.T20T Substitution - coding silent 23:15315546-15315546 - TCGA-60-2698-01 COSM755741 c.452T>A p.L151Q Substitution - Missense 23:15293238-15293238 - 09-365 COSM305626 c.667G>A p.D223N Substitution - Missense 23:15288061-15288061 - TCGA-BP-4768-01 COSM3363898 c.236T>C p.L79P Substitution - Missense 23:15302753-15302753 - TCGA-F4-6856-01 COSM1466488 c.68delT p.F23fs*5 Deletion - Frameshift 23:15315538-15315538 - LUAD-B00416 COSM355483 c.847+2T>G p.? Unknown 23:15287879-15287879 - TCGA-BR-8372-01 COSM4107877 c.674G>A p.G225D Substitution - Missense 23:15288054-15288054 - Pat_41_A COSM3235879 c.898G>A p.G300S Substitution - Missense 23:15283579-15283579 - TCGA-AP-A056-01 COSM1117540 c.804G>A p.A268A Substitution - coding silent 23:15287924-15287924 - SJMB026 COSM255977 c.228G>A p.G76G Substitution - coding silent 23:15302761-15302761 - TCGA-BS-A0UV-01 COSM1117689 c.207T>G p.L69L Substitution - coding silent 23:15302782-15302782 - TCGA-E9-A1RF-01 COSM1490651 c.803C>T p.A268V Substitution - Missense 23:15287925-15287925 - TCGA-24-1469-01 COSM115777 c.770G>C p.R257T Substitution - Missense 23:15287958-15287958 - TCGA-BS-A0UV-01 COSM1117564 c.639G>T p.K213N Substitution - Missense 23:15289520-15289520 - MZ7-mel COSM24383 c.367C>T p.H123Y Substitution - Missense 23:15297576-15297576 - CPCG0348-F1 COSM4880356 c.521-10G>T p.? Unknown 23:15289648-15289648 - TCGA-BR-4280-01 COSM4107890 c.594T>C p.T198T Substitution - coding silent 23:15289565-15289565 - KYSE-150 COSM3235875 c.934C>G p.L312V Substitution - Missense 23:15283543-15283543 - TCGA-AD-6901-01 COSM216185 c.865C>A p.Q289K Substitution - Missense 23:15283612-15283612 - TCGA-AX-A0J0-01 COSM1117635 c.302C>A p.S101Y Substitution - Missense 23:15297641-15297641 - TCGA-A5-A0VP-01 COSM1117542 c.766C>T p.R256C Substitution - Missense 23:15287962-15287962 - LUAD-S01357 COSM388013 c.820G>T p.V274L Substitution - Missense 23:15287908-15287908 - CSCC-40-T COSM4506350 c.717C>T p.S239S Substitution - coding silent 23:15288011-15288011 - T3024 COSM4663623 c.887G>A p.R296Q Substitution - Missense 23:15283590-15283590 - TCGA-BS-A0UF-01 COSM1117541 c.770G>T p.R257I Substitution - Missense 23:15287958-15287958 - T36 COSM4663627 c.230G>A p.R77H Substitution - Missense 23:15302759-15302759 - TCGA-AP-A051-01 COSM1117567 c.392G>A p.G131E Substitution - Missense 23:15293298-15293298 - CSCC-49-T COSM4561044 c.867G>A p.Q289Q Substitution - coding silent 23:15283610-15283610 - 587232 COSM1183718 c.326G>C p.G109A Substitution - Missense 23:15297617-15297617 - HCC170T COSM3708512 c.609C>T p.A203A Substitution - coding silent 23:15289550-15289550 - LUAD-CHTN-MAD06-00668 COSM360595 c.792G>A p.A264A Substitution - coding silent 23:15287936-15287936 - TCGA-G4-6628-01 COSM1466487 c.95delT p.L32fs*4 Deletion - Frameshift 23:15315511-15315511 - TCGA-BR-8382-01 COSM360595 c.792G>A p.A264A Substitution - coding silent 23:15287936-15287936 - TCGA-B5-A0JY-01 COSM1117804 c.157G>T p.E53* Substitution - Nonsense 23:15315449-15315449 - Pat_24_B COSM5877360 c.958C>T p.L320F Substitution - Missense 23:15283519-15283519 - TCGA-CA-6717-01 COSM1466489 c.34A>C p.N12H Substitution - Missense 23:15315572-15315572 - ICGC_MB36 COSM216185 c.865C>A p.Q289K Substitution - Missense 23:15283612-15283612 - TCGA-AN-A0AK-01 COSM1466487 c.95delT p.L32fs*4 Deletion - Frameshift 23:15315511-15315511 - TCGA-06-0875-01 COSM2152027 c.624G>T p.R208S Substitution - Missense 23:15289535-15289535 - HCC170 COSM3708512 c.609C>T p.A203A Substitution - coding silent 23:15289550-15289550 - TCGA-D1-A15X-01 COSM1117806 c.54T>C p.F18F Substitution - coding silent 23:15315552-15315552 - RK308_C01 COSM1736358 c.767G>A p.R256H Substitution - Missense 23:15287961-15287961 - TCGA-BR-8680-01 COSM4108021 c.128G>A p.G43E Substitution - Missense 23:15315478-15315478 - Gp2D COSM4628993 c.697C>A p.H233N Substitution - Missense 23:15288031-15288031 - 1953_T COSM3964926 c.481G>T p.V161L Substitution - Missense 23:15293209-15293209 - Gp2D COSM1466486 c.95_96insT p.L32fs*14 Insertion - Frameshift 23:15315510-15315511 - HCC2998 COSM3033700 c.151A>C p.I51L Substitution - Missense 23:15315455-15315455 - TCGA-AX-A0J1-01 COSM1117634 c.369C>T p.H123H Substitution - coding silent 23:15297574-15297574 - TCGA-CG-5721-01 COSM4107893 c.422G>A p.S141N Substitution - Missense 23:15293268-15293268 - Pat_66_A COSM5877362 c.913C>T p.Q305* Substitution - Nonsense 23:15283564-15283564 - HT115 COSM3236290 c.272T>C p.V91A Substitution - Missense 23:15297671-15297671 - T3021 COSM1466488 c.68delT p.F23fs*5 Deletion - Frameshift 23:15315538-15315538 - Gp5D COSM1466486 c.95_96insT p.L32fs*14 Insertion - Frameshift 23:15315510-15315511 - TCGA-EI-6884-01 COSM3424602 c.966C>A p.Y322* Substitution - Nonsense 23:15283511-15283511 - HCC2218 COSM24381 c.940_945delGAGCCA p.E314_L316>L Deletion - In frame 23:15283532-15283537 - ICGC_MB36 COSM216185 c.865C>A p.Q289K Substitution - Missense 23:15283612-15283612 - 2113170 COSM4167304 c.491C>T p.A164V Substitution - Missense 23:15293199-15293199 - QC2-35-T2 COSM5655171 c.703G>T p.A235S Substitution - Missense 23:15288025-15288025 - TCGA-BR-6452-01 COSM4107874 c.839T>C p.L280P Substitution - Missense 23:15287889-15287889 - TCGA-CA-6717-01 COSM1466468 c.316T>C p.C106R Substitution - Missense 23:15297627-15297627 - P106 COSM1736358 c.767G>A p.R256H Substitution - Missense 23:15287961-15287961 - TCGA-13-1408-01 COSM119819 c.791C>A p.A264E Substitution - Missense 23:15287937-15287937 - SJMB026 COSM255977 c.228G>A p.G76G Substitution - coding silent 23:15302761-15302761 - TCGA-CM-6678-01 COSM3694419 c.937C>A p.P313T Substitution - Missense 23:15283540-15283540 - CSCC-55-T COSM1117805 c.120C>T p.I40I Substitution - coding silent 23:15315486-15315486 - TCGA-AX-A0J0-01 COSM1117807 c.52T>C p.F18L Substitution - Missense 23:15315554-15315554 - 08-P462 COSM4589299 c.60delG p.F23fs*5 Deletion - Frameshift 23:15315546-15315546 - 2492708 COSM5718254 c.310G>A p.E104K Substitution - Missense 23:15297633-15297633 - TCGA-FW-A3R5-06 COSM3913633 c.574G>A p.E192K Substitution - Missense 23:15289585-15289585 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.352183 Xp22.31 300626

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A - Frameshift p.F23Sfs*5 c.68delT X 15333660 STAD A G Missense p.L79P c.236T>C X 15320875 RCCC A G Synonymous p.T198T c.594T>C X 15307687 STAD C A Missense p.R208S c.624G>T X 15307657 GBM CC TT Missense p.G126K c.376_377delinsAA X 15311435 CM C G Missense p.R257T c.770G>C X 15306080 OV C T Missense p.G154R c.460G>A X 15311352 LUAD C T Missense p.V274M c.820G>A X 15306030 ESCA G A Missense p.A268V c.803C>T X 15306047 BRCA G A Missense p.A48V c.143C>T X 15333585 LUSC G A Missense p.R256C c.766C>T X 15306084 AML G A Missense p.R256C c.766C>T X 15306084 UCEC G A Synonymous p.L267L c.799C>T X 15306051 BRCA GCCAGA - InFrameDeletion p.E314_P315delEP c.940_945delGAGCCA X 15301658 BRCA G T Missense p.A164D c.491C>A X 15311321 LUSC G T Missense p.A264E c.791C>A X 15306059 LUAD G T Missense p.A264E c.791C>A X 15306059 OV G T Missense p.H103Q c.309C>A X 15315756 STAD G T Missense p.Q289K c.865C>A X 15301734 MB G T Synonymous p.I55I c.165C>A X 15333563 STAD