PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ASB11 CUL5 24337577 biogrid exp P G P P P P P G G P PSMD2 ASB11 24337577 biogrid exp P G P P P P P G G P RPN1 ASB11 24337577 biogrid exp P G P P P P G G P ATP5B ASB11 24337577 biogrid exp P G P P P P P G G P ERLIN1 ASB11 24337577 biogrid exp P G P P P P P G G P PRPS1 ASB11 24337577 biogrid exp P G P P P P G G P DDOST ASB11 24337577 biogrid exp P G P P P P P G G P UBC ASB11 24337577 biogrid exp P G P P P P P G G P PSMA2 ASB11 24337577 biogrid exp P G P P P P P G G P PSMB2 ASB11 24337577 biogrid exp P G P P P P P G G P PSMC3 ASB11 24337577 biogrid exp P G P P P P P G G P PSMD11 ASB11 24337577 biogrid exp P G P P P G G GANAB ASB11 24337577 biogrid exp P G P P P P P G G P SLC3A2 ASB11 24337577 biogrid exp G P P G G ASB11 RAPGEFL1 16082366 pred P P P P SOS1 ASB11 16082366 pred P G P P P P G G P NOTCH2 ASB11 23023127 pred G G G P RASGRP1 ASB11 16082366 pred G RALGPS2 ASB11 16082366 pred P P P P P G P BCAR3 ASB11 16082366 pred P G P P P P P G G P RASGEF1B ASB11 16082366 pred P P P P SH2D3C ASB11 16082366 pred P G P P G G P RASGEF1C ASB11 16082366 pred P P P P P P P RAPGEF1 ASB11 16082366 pred P G P P P P G G P RGL2 ASB11 16082366 pred G P P P G G P RGL4 ASB11 16082366 pred P P P SOS2 ASB11 16082366 pred P G P P P P G G P RAPGEF3 ASB11 16082366 pred P G P P P P P G P ASB11 RGL1 16082366 pred P G P P P P P G G P RASGRF2 ASB11 16082366 pred P G P P P P P G G P RASGRP2 ASB11 16082366 pred P G P P P P G G P RALGDS ASB11 16082366 pred P G P P P P P G G P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8WXH4 Q93034 imaging technique 24337577 colocalization X 2 D3DR65 Q8WXH4 affinity chromatography technology 24337577 physical association X 2 P0CG48 Q8WXH4 enzymatic study 24337577 direct interaction X 2 P17980 Q8WXH4 affinity chromatography technology 24337577 physical association X 2 O00231 Q8WXH4 affinity chromatography technology 24337577 physical association X 2 A0A024RA52 Q8WXH4 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 J3KPF3 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 B7Z478 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 Q13200 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 Q14697-2 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 P06576 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 P04843 affinity chromatography technology 24337577 physical association X 2 Q8WXH4 P04843 enzymatic study 24337577 direct interaction X 2 Q8WXH4 P04843 imaging technique 24337577 colocalization X 2 P60891-2 Q8WXH4 affinity chromatography technology 24337577 physical association X 2 A0A024RAD5 Q8WXH4 affinity chromatography technology 24337577 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WXH4 P04843 ASB11 RPN1 0.343 24337577 Q8WXH4 P17980 ASB11 PSMC3 0.126 24337577 Q8WXH4 O00231 ASB11 PSMD11 0.126 24337577 Q8WXH4 O75477 ASB11 ERLIN1 0.126 24337577 Q8WXH4 P0CG48 ASB11 UBC 0.183 24337577 Q8WXH4 P06576 ASB11 ATP5B 0.126 24337577 Q8WXH4 P08195 ASB11 SLC3A2 0.126 24337577 Q93034 Q8WXH4 CUL5 ASB11 0.081 24337577 Q8WXH4 P49721 ASB11 PSMB2 0.126 24337577 Q8WXH4 P25787 ASB11 PSMA2 0.126 24337577 Q8WXH4 P39656 ASB11 DDOST 0.126 24337577 Q8WXH4 Q14697 ASB11 GANAB 0.126 24337577 Q8WXH4 P60891 ASB11 PRPS1 0.126 24337577 Q8WXH4 Q13200 ASB11 PSMD2 0.126 24337577

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PSMD11 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database ERLIN1 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database RPN1 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database ATP5B ASB11 MI:0045 experimental interaction detection MI:0461 interaction database SLC3A2 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database UBC ASB11 MI:0045 experimental interaction detection MI:0461 interaction database PSMC3 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database PSMA2 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database DDOST ASB11 MI:0045 experimental interaction detection MI:0461 interaction database PSMB2 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database PRPS1 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database PSMD2 ASB11 MI:0045 experimental interaction detection MI:0461 interaction database GANAB ASB11 MI:0045 experimental interaction detection MI:0461 interaction database TCEB1 ASB11 MI:0362 inference MI:1106 pathways database TCEB2 ASB11 MI:0362 inference MI:1106 pathways database ASB11 CUL5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ASB11 RNF7 MI:0362 inference MI:1106 pathways database