PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CUL4B BRWD3 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP GP G GP G P GP G GP G GP GP GP GP GP GP GP G UBXN7 BRWD3 18775313 biogrid,intact exp G GP G G GP GP G GP GP G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP G TERF1 BRWD3 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G CSNK2A1 BRWD3 26344197 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP G BRWD3 PBRM1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G P GP G GP G GP G GP GP G GP GP G BRPF1 BRWD3 23023127 pred G GP G G GP GP G GP G G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP G BRWD3 ARHGAP20 21836163 pred G GP G P GP G GP GP G P GP GP GP G P GP G GP G P GP GP GP P GP GP G PTPN3 BRWD3 21836163 pred G GP G G G GP G GP GP G GP GP GP GP G P GP G GP G GP GP GP GP P GP GP G BRWD3 DLG3 21836163 pred G G G G G GP G G G G GP G G G G GP G G G GP G G G G GP GP G BRWD3 CREBBP 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G P GP G GP G GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6RI45 anti tag coimmunoprecipitation 18775313 association C 22 Q6RI45 Q81Y80 two hybrid pooling approach 20711500 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q81Y80 Q6RI45 ACNA BRWD3 0.126 20711500 Q6RI45 Q13620 BRWD3 CUL4B 0.236 26496610 Q9CWZ3 Q6RI45 RBM8A BRWD3 0.236 26496610 Q6RI45 Q3TCH7 BRWD3 CUL4A 0.236 26496610 Q6RI45 A2APB8 BRWD3 TPX2 0.236 26496610 Q6RI45 P54274 BRWD3 TERF1 0.236 26496610 Q6RI45 O94888 BRWD3 UBXN7 0.332 18775313,26389662 Q6RI45 P68400 BRWD3 CSNK2A1 0.081 26344197

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 WDR91 BRWD3 MI:0362 inference MI:0461 interaction database MRPL33 BRWD3 MI:0362 inference MI:0461 interaction database UBXN7 BRWD3 MI:0045 experimental interaction detection MI:0461 interaction database PARP1 BRWD3 MI:0362 inference MI:0461 interaction database UBC BRWD3 MI:0045 experimental interaction detection MI:0461 interaction database UBTF BRWD3 MI:0362 inference MI:0461 interaction database RPL7 BRWD3 MI:0362 inference MI:0461 interaction database RPL17 BRWD3 MI:0362 inference MI:0461 interaction database TARS BRWD3 MI:0362 inference MI:0461 interaction database RFC2 BRWD3 MI:0362 inference MI:0461 interaction database RFC1 BRWD3 MI:0362 inference MI:0461 interaction database RPL4 BRWD3 MI:0362 inference MI:0461 interaction database RPL3 BRWD3 MI:0362 inference MI:0461 interaction database RFC3 BRWD3 MI:0362 inference MI:0461 interaction database RPL35 BRWD3 MI:0362 inference MI:0461 interaction database TERF1 BRWD3 MI:0045 experimental interaction detection MI:0461 interaction database RPL26 BRWD3 MI:0362 inference MI:0461 interaction database RPL37A BRWD3 MI:0362 inference MI:0461 interaction database RBX1 BRWD3 MI:0362 inference MI:0461 interaction database RPL31 BRWD3 MI:0362 inference MI:0461 interaction database RPL11 BRWD3 MI:0362 inference MI:0461 interaction database MRPS25 BRWD3 MI:0362 inference MI:0461 interaction database MRPS35 BRWD3 MI:0362 inference MI:0461 interaction database MRPS15 BRWD3 MI:0362 inference MI:0461 interaction database RPL18A BRWD3 MI:0362 inference MI:0461 interaction database RPL18 BRWD3 MI:0362 inference MI:0461 interaction database MRPL49 BRWD3 MI:0362 inference MI:0461 interaction database CUL4A BRWD3 MI:0362 inference MI:0461 interaction database CUL4B BRWD3 MI:0045 experimental interaction detection MI:0461 interaction database NEDD8 BRWD3 MI:0362 inference MI:0461 interaction database DDB1 BRWD3 MI:0362 inference MI:0461 interaction database MRPL2 BRWD3 MI:0362 inference MI:0461 interaction database MRPL14 BRWD3 MI:0362 inference MI:0461 interaction database WDR74 BRWD3 MI:0362 inference MI:0461 interaction database BRWD3 KRBA2 MI:0362 inference MI:0461 interaction database BRWD3 MRPL21 MI:0362 inference MI:0461 interaction database BRWD3 MRPL43 MI:0362 inference MI:0461 interaction database BRWD3 GADD45GIP1 MI:0362 inference MI:0461 interaction database BRWD3 MRPL30 MI:0362 inference MI:0461 interaction database BRWD3 PHIP MI:0362 inference MI:0461 interaction database BRWD3 MRPS31 MI:0362 inference MI:0461 interaction database BRWD3 USP7 MI:0362 inference MI:0461 interaction database BRWD3 MRPL24 MI:0362 inference MI:0461 interaction database BRWD3 APOBEC3D MI:0362 inference MI:0461 interaction database BRWD3 MRPL38 MI:0362 inference MI:0461 interaction database BRWD3 MRPL53 MI:0362 inference MI:0461 interaction database BRWD3 MRPL20 MI:0362 inference MI:0461 interaction database BRWD3 MRPL13 MI:0362 inference MI:0461 interaction database BRWD3 MRPL4 MI:0362 inference MI:0461 interaction database BRWD3 MRPL1 MI:0362 inference MI:0461 interaction database BRWD3 MRPL37 MI:0362 inference MI:0461 interaction database BRWD3 MRPL18 MI:0362 inference MI:0461 interaction database BRWD3 MRPL46 MI:0362 inference MI:0461 interaction database BRWD3 MRPL47 MI:0362 inference MI:0461 interaction database BRWD3 BRWD1 MI:0362 inference MI:0461 interaction database BRWD3 LYAR MI:0362 inference MI:0461 interaction database BRWD3 TPX2 MI:0362 inference MI:0461 interaction database BRWD3 WDR3 MI:0362 inference MI:0461 interaction database BRWD3 RPL36 MI:0362 inference MI:0461 interaction database BRWD3 RBM8A MI:0362 inference MI:0461 interaction database