PTM - CPLM Gene Name UniProt ID Type Position Code BRWD3 Q6RI45 Ubiquitination 987 K

PTM - dbPAF Gene Name UniProt ID Position Type Species BRWD3 Q6RI45 1024 Y Homo sapiens(Human) BRWD3 Q6RI45 1040 Y Homo sapiens(Human) BRWD3 Q6RI45 1264 S Homo sapiens(Human) BRWD3 Q6RI45 1265 T Homo sapiens(Human) BRWD3 Q6RI45 1271 T Homo sapiens(Human) BRWD3 Q6RI45 1278 S Homo sapiens(Human) BRWD3 Q6RI45 1386 S Homo sapiens(Human) BRWD3 Q6RI45 1404 Y Homo sapiens(Human) BRWD3 Q6RI45 1405 T Homo sapiens(Human) BRWD3 Q6RI45 1406 S Homo sapiens(Human) BRWD3 Q6RI45 1410 S Homo sapiens(Human) BRWD3 Q6RI45 1413 Y Homo sapiens(Human) BRWD3 Q6RI45 1454 S Homo sapiens(Human) BRWD3 Q6RI45 1455 S Homo sapiens(Human) BRWD3 Q6RI45 1466 S Homo sapiens(Human) BRWD3 Q6RI45 1569 T Homo sapiens(Human) BRWD3 Q6RI45 1577 S Homo sapiens(Human) BRWD3 Q6RI45 1579 S Homo sapiens(Human) BRWD3 Q6RI45 1599 S Homo sapiens(Human) BRWD3 Q6RI45 1603 T Homo sapiens(Human) BRWD3 Q6RI45 1606 S Homo sapiens(Human) BRWD3 Q6RI45 1611 S Homo sapiens(Human) BRWD3 Q6RI45 1612 S Homo sapiens(Human) BRWD3 Q6RI45 1763 S Homo sapiens(Human) BRWD3 Q6RI45 268 T Homo sapiens(Human) BRWD3 Q6RI45 312 T Homo sapiens(Human) BRWD3 Q6RI45 334 T Homo sapiens(Human) BRWD3 Q6RI45 335 T Homo sapiens(Human) BRWD3 Q6RI45 337 S Homo sapiens(Human) BRWD3 Q6RI45 338 T Homo sapiens(Human) BRWD3 Q6RI45 577 T Homo sapiens(Human) BRWD3 Q6RI45 6 T Homo sapiens(Human) BRWD3 Q6RI45 678 S Homo sapiens(Human) BRWD3 Q6RI45 685 S Homo sapiens(Human) BRWD3 Q6RI45 693 S Homo sapiens(Human) BRWD3 Q6RI45 702 S Homo sapiens(Human) BRWD3 Q6RI45 703 S Homo sapiens(Human) BRWD3 Q6RI45 884 S Homo sapiens(Human) BRWD3 Q6RI45 885 S Homo sapiens(Human) BRWD3 Q6RI45 886 S Homo sapiens(Human) BRWD3 Q6RI45 948 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q6RI45 K1402-m2 Methylation RQIFNNSkAytsNKK Q6RI45 R1740-m1 Methylation FDTMFSGrFSrLPRI Q6RI45 R1743-m1 Methylation MFSGrFSrLPRIKTR Q6RI45 T6-p Phosphorylation __MAAAPtQIEAELY Q6RI45 T268-p Phosphorylation QGHSASItSIQFCPS Q6RI45 T312-p Phosphorylation RDRPVKFtERSRPGV Q6RI45 S337-p Phosphorylation GMFITTGstDHVIRI Q6RI45 T338-p Phosphorylation MFITTGstDHVIRIY Q6RI45 S678-p Phosphorylation LPVNRAYsVNGALRs Q6RI45 S685-p Phosphorylation sVNGALRsPNMDISS Q6RI45 S693-p Phosphorylation PNMDISSsPNIRLRR Q6RI45 S702-p Phosphorylation NIRLRRHssQIEGVR Q6RI45 S703-p Phosphorylation IRLRRHssQIEGVRQ Q6RI45 S885-p Phosphorylation TTRKICSssDEENLK Q6RI45 S886-p Phosphorylation TRKICSssDEENLKS Q6RI45 Y948-p Phosphorylation QMGDELIyFRQGHEA Q6RI45 Y1024-p Phosphorylation GESFSIKyHDMPDVI Q6RI45 Y1040-p Phosphorylation FLVLHQFyNEAKERN Q6RI45 S1264-p Phosphorylation IKAEERNstDAEEDt Q6RI45 T1265-p Phosphorylation KAEERNstDAEEDtE Q6RI45 T1271-p Phosphorylation stDAEEDtEIVDLDs Q6RI45 S1278-p Phosphorylation tEIVDLDsDGPGTSS Q6RI45 S1386-p Phosphorylation LEAGNYGsPLEFYKD Q6RI45 Y1404-p Phosphorylation IFNNSkAytsNKKsR Q6RI45 T1405-p Phosphorylation FNNSkAytsNKKsRI Q6RI45 S1406-p Phosphorylation NNSkAytsNKKsRIy Q6RI45 S1410-p Phosphorylation AytsNKKsRIySMML Q6RI45 Y1413-p Phosphorylation sNKKsRIySMMLRLS Q6RI45 S1455-p Phosphorylation YRkRLRSsSSSLSSS Q6RI45 S1466-p Phosphorylation LSSSGAPsPKGKQKQ Q6RI45 T1569-p Phosphorylation GDGREPRtGIKRKLL Q6RI45 S1577-p Phosphorylation GIKRKLLsAsEEDEN Q6RI45 S1579-p Phosphorylation KRKLLsAsEEDENMG Q6RI45 S1599-p Phosphorylation KKETKEKsHLStSEs Q6RI45 T1603-p Phosphorylation KEKsHLStSEsGELG Q6RI45 S1606-p Phosphorylation sHLStSEsGELGssL Q6RI45 S1611-p Phosphorylation SEsGELGssLSSEST Q6RI45 S1612-p Phosphorylation EsGELGssLSSESTC Q6RI45 S1763-p Phosphorylation TVLYNDDsDNDNFVS Q6RI45 K987-ub Ubiquitination LREQEFVkIVGIKYE Q6RI45 K1450-ub Ubiquitination RRRPRYRkRLRSsSS

PTM - dbPTM UniProt ID Position Code Type Resources References Q6RI45 703 S Phosphorylation Swiss-Prot 1010711 17525332 Q6RI45 1455 S Phosphorylation Swiss-Prot 1010711 17287340 Q6RI45 1466 S Phosphorylation Swiss-Prot 1010711 17287340 Q6RI45 1569 T Phosphorylation Swiss-Prot 1010711 17081983 Q6RI45 703 S Phosphorylation PhosphoELM.10011 17525332 Q6RI45 1455 S Phosphorylation PhosphoELM.10011 17287340 Q6RI45 1466 S Phosphorylation PhosphoELM.10011 17287340 Q6RI45 1569 T Phosphorylation PhosphoELM.10011 17081983 Q6RI45 987 K Ubiquitylation Phosphositeplus.1010730 21890473 Q6RI45 1264 S Phosphorylation Phosphositeplus.1010730 21406692 Q6RI45 1455 S Phosphorylation Phosphositeplus.1010730 17287340 Q6RI45 1466 S Phosphorylation Phosphositeplus.1010730 17287340 Q6RI45 1577 S Phosphorylation Phosphositeplus.1010730 20068231;20363803 Q6RI45 1579 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q6RI45 337 S Phosphorylation Phosphositeplus.1010730 22115753 Q6RI45 702 S Phosphorylation Phosphositeplus.1010730 20363803 Q6RI45 703 S Phosphorylation Phosphositeplus.1010730 17525332;20068231 Q6RI45 1265 T Phosphorylation Phosphositeplus.1010730 21406692 Q6RI45 1569 T Phosphorylation Phosphositeplus.1010730 17081983;20068231;21406692 Q6RI45 268 T Phosphorylation Phosphositeplus.1010730 20058876 Q6RI45 338 T Phosphorylation Phosphositeplus.1010730 22115753 Q6RI45 703 S Phosphorylation HPRD 9.0 17525332,20068231 Q6RI45 1454 S Phosphorylation HPRD 9.0 20068231 Q6RI45 1455 S Phosphorylation HPRD 9.0 17287340 Q6RI45 1466 S Phosphorylation HPRD 9.0 17287340,20068231 Q6RI45 1577 S Phosphorylation HPRD 9.0 20068231 Q6RI45 268 T Phosphorylation HPRD 9.0 20058876 Q6RI45 1569 T Phosphorylation HPRD 9.0 17081983,20068231 Q6RI45 1569 T Phosphorylation SysPTM 1.1 18785766;17081983

PTM - HPRD Symbol Position Code Type References BRWD3 1454 S Phosphorylation 20068231 BRWD3 1455 S Phosphorylation 17287340 BRWD3 1466 S Phosphorylation 17287340,20068231 BRWD3 1569 T Phosphorylation 17081983,20068231 BRWD3 1577 S Phosphorylation 20068231 BRWD3 268 T Phosphorylation 20058876 BRWD3 703 S Phosphorylation 17525332,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q6RI45 1455 S 17287340 HTP Phosphorylation Q6RI45 1466 S 17287340 HTP Phosphorylation Q6RI45 1569 T 17081983 HTP Phosphorylation Q6RI45 703 S 17525332 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q6RI45 693 Phosphoserine 23186163 Q6RI45 703 Phosphoserine 20068231 Q6RI45 1577 Phosphoserine 20068231 Q6RI45 1579 Phosphoserine 21406692;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type BRWD3 IPI00167547 S 703 RLRRHSpSQIEGVR phosphorylation BRWD3 IPI00167547 T 1569 DGREPRpTGIKRKL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 254065 129012 - K Ubiquitination 21890473

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID BRWD3 Homo sapiens (Human) 816 "816,REQEFVKIVGIKY" 816:21890473 BRWD3 Homo sapiens (Human) 816 "816,REQEFVKIVGIKY" 816:21890473 BRWD3 Homo sapiens (Human) 987 "987,REQEFVKIVGIKY" 987:21890473 BRWD3 Homo sapiens (Human) 987 "987,REQEFVKIVGIKY" 987:21890473 BRWD3 Homo sapiens (Human) 816 "816,REQEFVKIVGIKY" 816:21890473 BRWD3 Homo sapiens (Human) 583 "583,REQEFVKIVGIKY" 583:21890473 BRWD3 Homo sapiens (Human) 583 "583,REQEFVKIVGIKY" 583:21890473