Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 14 39901157 39901157 + Silent SNP C C A TCGA-OR-A5JW-01A-11D-A29I-10 TCGA-OR-A5JW-10A-01D-A29L-10 g.chr14:39901157C>A c.210G>T c.(208-210)tcG>tcT p.S70S BLCA 14 39868857 39868857 + Missense_Mutation SNP G G A TCGA-DK-A1A3-01A-11D-A13W-08 TCGA-DK-A1A3-10A-01D-A13W-08 g.chr14:39868857G>A c.1531C>T c.(1531-1533)Cat>Tat p.H511Y BLCA 14 39900843 39900843 + Nonsense_Mutation SNP G G T TCGA-E7-A5KF-01A-11D-A289-08 TCGA-E7-A5KF-10A-01D-A289-08 g.chr14:39900843G>T c.524C>A c.(523-525)tCa>tAa p.S175* BRCA 14 39870578 39870578 + Missense_Mutation SNP C C T TCGA-BH-A2L8-01A-11D-A18P-09 TCGA-BH-A2L8-10A-01D-A18P-09 g.chr14:39870578C>T c.1198G>A c.(1198-1200)Gat>Aat p.D400N BRCA 14 39870683 39870683 + Nonsense_Mutation SNP G G A TCGA-A8-A09Z-01A-11W-A019-09 TCGA-A8-A09Z-10A-01W-A021-09 g.chr14:39870683G>A c.1093C>T c.(1093-1095)Cga>Tga p.R365* BRCA 14 39870722 39870722 + Missense_Mutation SNP C C T TCGA-D8-A27R-01A-11D-A16D-09 TCGA-D8-A27R-10A-01D-A16D-09 g.chr14:39870722C>T c.1054G>A c.(1054-1056)Gac>Aac p.D352N BRCA 14 39870860 39870860 + Missense_Mutation SNP C C T TCGA-BH-A0HF-01A-11W-A071-09 TCGA-BH-A0HF-10A-01W-A071-09 g.chr14:39870860C>T c.916G>A c.(916-918)Gtg>Atg p.V306M BRCA 14 39871049 39871049 + Missense_Mutation SNP C C T TCGA-D8-A27G-01A-11D-A16D-09 TCGA-D8-A27G-10A-01D-A16D-09 g.chr14:39871049C>T c.727G>A c.(727-729)Gaa>Aaa p.E243K BRCA 14 39900893 39900893 + Silent SNP A A C TCGA-B6-A408-01A-12D-A243-09 TCGA-B6-A408-10A-01D-A243-09 g.chr14:39900893A>C c.474T>G c.(472-474)ggT>ggG p.G158G CESC 14 39868938 39868938 + Missense_Mutation SNP C C T TCGA-C5-A1MK-01A-11D-A14W-08 TCGA-C5-A1MK-10A-01D-A14W-08 g.chr14:39868938C>T c.1450G>A c.(1450-1452)Gat>Aat p.D484N CESC 14 39870958 39870958 + Missense_Mutation SNP G G C TCGA-LP-A5U2-01A-11D-A28B-09 TCGA-LP-A5U2-10A-01D-A28E-09 g.chr14:39870958G>C c.818C>G c.(817-819)tCt>tGt p.S273C COAD 14 39868943 39868943 + Missense_Mutation SNP C C G TCGA-D5-6928-01A-11D-1924-10 TCGA-D5-6928-10A-01D-1924-10 g.chr14:39868943C>G c.1445G>C c.(1444-1446)gGc>gCc p.G482A COAD 14 39870502 39870502 + Missense_Mutation SNP A A C TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr14:39870502A>C c.1274T>G c.(1273-1275)tTt>tGt p.F425C COAD 14 39870630 39870630 + Silent SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr14:39870630T>C c.1146A>G c.(1144-1146)gaA>gaG p.E382E COAD 14 39870983 39870983 + Missense_Mutation SNP T T C TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chr14:39870983T>C c.793A>G c.(793-795)Acc>Gcc p.T265A COADREAD 14 39868943 39868943 + Missense_Mutation SNP C C G TCGA-D5-6928-01A-11D-1924-10 TCGA-D5-6928-10A-01D-1924-10 g.chr14:39868943C>G c.1445G>C c.(1444-1446)gGc>gCc p.G482A COADREAD 14 39870502 39870502 + Missense_Mutation SNP A A C TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr14:39870502A>C c.1274T>G c.(1273-1275)tTt>tGt p.F425C COADREAD 14 39870630 39870630 + Silent SNP T T C TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr14:39870630T>C c.1146A>G c.(1144-1146)gaA>gaG p.E382E COADREAD 14 39870983 39870983 + Missense_Mutation SNP T T C TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chr14:39870983T>C c.793A>G c.(793-795)Acc>Gcc p.T265A DLBC 14 39870594 39870594 + Silent SNP T T C TCGA-G8-6325-01A-11D-2210-10 TCGA-G8-6325-10A-01D-2210-10 g.chr14:39870594T>C c.1182A>G c.(1180-1182)ctA>ctG p.L394L GBMLGG 14 39870639 39870639 + Silent SNP G G A TCGA-HT-7855-01A-11D-2395-08 TCGA-HT-7855-10A-01D-2396-08 g.chr14:39870639G>A c.1137C>T c.(1135-1137)atC>atT p.I379I HNSC 14 39870602 39870602 + Missense_Mutation SNP T T C TCGA-CN-A49B-01A-31D-A24D-08 TCGA-CN-A49B-10A-01D-A24F-08 g.chr14:39870602T>C c.1174A>G c.(1174-1176)Ata>Gta p.I392V HNSC 14 39871062 39871078 + Splice_Site DEL AATTCTATAAGGAAAAC AATTCTATAAGGAAAAC - TCGA-CN-5367-01A-01D-1434-08 TCGA-CN-5367-10A-01D-1434-08 g.chr14:39871062_39871078delAATTCTATAAGGAAAAC c.711_714delGTTTTCCTTATAGAATT c.(709-714)cagttt>ca p.QF237fs HNSC 14 39871066 39871066 + Splice_Site SNP C C T TCGA-P3-A6T5-01A-11D-A34J-08 TCGA-P3-A6T5-10A-01D-A34M-08 g.chr14:39871066C>T c.e3-1 KIPAN 14 39868808 39868808 + Missense_Mutation SNP G G A TCGA-BQ-5877-01A-11D-1589-08 TCGA-BQ-5877-11A-01D-1589-08 g.chr14:39868808G>A c.1580C>T c.(1579-1581)gCa>gTa p.A527V KIPAN 14 39871674 39871674 + Missense_Mutation SNP A A G TCGA-B1-A47M-01A-11D-A25F-10 TCGA-B1-A47M-10A-01D-A25F-10 g.chr14:39871674A>G c.641T>C c.(640-642)cTa>cCa p.L214P KIRP 14 39868808 39868808 + Missense_Mutation SNP G G A TCGA-BQ-5877-01A-11D-1589-08 TCGA-BQ-5877-11A-01D-1589-08 g.chr14:39868808G>A c.1580C>T c.(1579-1581)gCa>gTa p.A527V KIRP 14 39871674 39871674 + Missense_Mutation SNP A A G TCGA-B1-A47M-01A-11D-A25F-10 TCGA-B1-A47M-10A-01D-A25F-10 g.chr14:39871674A>G c.641T>C c.(640-642)cTa>cCa p.L214P LGG 14 39870639 39870639 + Silent SNP G G A TCGA-HT-7855-01A-11D-2395-08 TCGA-HT-7855-10A-01D-2396-08 g.chr14:39870639G>A c.1137C>T c.(1135-1137)atC>atT p.I379I LIHC 14 39868748 39868748 + Missense_Mutation SNP T T C TCGA-DD-A1EG-01A-11D-A20W-10 TCGA-DD-A1EG-10A-01D-A20W-10 g.chr14:39868748T>C c.1640A>G c.(1639-1641)gAg>gGg p.E547G LIHC 14 39900875 39900875 + Silent SNP A A G TCGA-EP-A2KA-01A-11D-A183-10 TCGA-EP-A2KA-10A-01D-A183-10 g.chr14:39900875A>G c.492T>C c.(490-492)acT>acC p.T164T LIHC 14 39900902 39900902 + Silent SNP C C T TCGA-EP-A2KA-01A-11D-A183-10 TCGA-EP-A2KA-10A-01D-A183-10 g.chr14:39900902C>T c.465G>A c.(463-465)ggG>ggA p.G155G LUAD 14 39868928 39868928 + Missense_Mutation SNP A A G TCGA-44-7660-01A-11D-2063-08 TCGA-44-7660-10A-01D-2063-08 g.chr14:39868928A>G c.1460T>C c.(1459-1461)gTg>gCg p.V487A LUAD 14 39870542 39870542 + Missense_Mutation SNP C C G TCGA-73-4666-01A-01D-1265-08 TCGA-73-4666-11A-01D-1265-08 g.chr14:39870542C>G c.1234G>C c.(1234-1236)Gat>Cat p.D412H LUAD 14 39870665 39870665 + Silent SNP G G T TCGA-64-5781-01A-01D-1625-08 TCGA-64-5781-10A-01D-1625-08 g.chr14:39870665G>T c.1111C>A c.(1111-1113)Cgg>Agg p.R371R LUAD 14 39870751 39870751 + Missense_Mutation SNP T T A TCGA-05-4420-01A-01D-1265-08 TCGA-05-4420-10A-01D-1265-08 g.chr14:39870751T>A c.1025A>T c.(1024-1026)cAc>cTc p.H342L LUAD 14 39900943 39900943 + Missense_Mutation SNP C C T TCGA-55-7907-01A-11D-2167-08 TCGA-55-7907-10A-01D-2167-08 g.chr14:39900943C>T c.424G>A c.(424-426)Gaa>Aaa p.E142K LUSC 14 39900916 39900916 + Missense_Mutation SNP C C G TCGA-60-2722-01A-01D-1522-08 TCGA-60-2722-11A-01D-1522-08 g.chr14:39900916C>G c.451G>C c.(451-453)Ggc>Cgc p.G151R OV 14 39900992 39900992 + Silent SNP C C A TCGA-13-2061-01A-01D-1526-09 TCGA-13-2061-10A-01D-1526-09 g.chr14:39900992C>A c.375G>T c.(373-375)ctG>ctT p.L125L PAAD 14 39868915 39868915 + Silent SNP G G A TCGA-FB-AAQ1-01A-12D-A40W-08 TCGA-FB-AAQ1-11A-11D-A40W-08 g.chr14:39868915G>A c.1473C>T c.(1471-1473)acC>acT p.T491T PAAD 14 39871612 39871612 + Frame_Shift_Del DEL T T - TCGA-F2-7273-01A-11D-2154-08 TCGA-F2-7273-10A-01D-2154-08 g.chr14:39871612delT c.703delA c.(703-705)attfs p.I235fs PAAD 14 39871612 39871612 + Frame_Shift_Del DEL T T - TCGA-HV-A7OP-01A-11D-A33T-08 TCGA-HV-A7OP-10A-01D-A33W-08 g.chr14:39871612delT c.703delA c.(703-705)attfs p.I235fs PCPG 14 39871700 39871700 + Missense_Mutation SNP A A C TCGA-RW-A7CZ-01A-11D-A35D-08 TCGA-RW-A7CZ-10B-01D-A35B-08 g.chr14:39871700A>C c.615T>G c.(613-615)ttT>ttG p.F205L PRAD 14 39871008 39871008 + Silent SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr14:39871008G>A c.768C>T c.(766-768)tcC>tcT p.S256S SKCM 14 39868916 39868916 + Missense_Mutation SNP G G A TCGA-EE-A29L-06A-12D-A196-08 TCGA-EE-A29L-10A-01D-A198-08 g.chr14:39868916G>A c.1472C>T c.(1471-1473)aCc>aTc p.T491I SKCM 14 39870725 39870725 + Silent SNP G G A TCGA-EE-A3AF-06A-11D-A196-08 TCGA-EE-A3AF-10A-01D-A198-08 g.chr14:39870725G>A c.1051C>T c.(1051-1053)Ctg>Ttg p.L351L SKCM 14 39870734 39870734 + Missense_Mutation SNP G G T TCGA-D3-A51K-06A-11D-A25O-08 TCGA-D3-A51K-10A-01D-A25O-08 g.chr14:39870734G>T c.1042C>A c.(1042-1044)Cac>Aac p.H348N

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 14 39868857 39868857 single base substitution G A 3_prime_UTR_variant BLCA-US 14 39868857 39868857 single base substitution G A missense_variant H511Y 1531C>T BOCA-FR 14 39890233 39890233 single base substitution T C intron_variant BOCA-FR 14 39901259 39901267 deletion of <=200bp TCGCAGCTG - inframe_deletion QLR34 BOCA-FR 14 39901259 39901267 deletion of <=200bp TCGCAGCTG - intron_variant BOCA-FR 14 39901259 39901267 deletion of <=200bp TCGCAGCTG - upstream_gene_variant BRCA-EU 14 39862748 39862748 single base substitution G A downstream_gene_variant BRCA-EU 14 39863285 39863285 single base substitution C T downstream_gene_variant BRCA-EU 14 39863506 39863506 single base substitution C T downstream_gene_variant BRCA-EU 14 39864153 39864153 single base substitution A C downstream_gene_variant BRCA-EU 14 39864766 39864766 single base substitution C G downstream_gene_variant BRCA-EU 14 39868119 39868119 single base substitution T A 3_prime_UTR_variant BRCA-EU 14 39868119 39868119 single base substitution T A downstream_gene_variant BRCA-EU 14 39868634 39868634 single base substitution A G 3_prime_UTR_variant BRCA-EU 14 39868634 39868634 single base substitution A G downstream_gene_variant BRCA-EU 14 39869176 39869176 deletion of <=200bp A - intron_variant BRCA-EU 14 39870037 39870037 single base substitution C T intron_variant BRCA-EU 14 39870337 39870337 single base substitution G A intron_variant BRCA-EU 14 39872369 39872369 single base substitution A T intron_variant BRCA-EU 14 39872568 39872568 single base substitution G A intron_variant BRCA-EU 14 39874529 39874529 single base substitution C G intron_variant BRCA-EU 14 39876851 39876851 single base substitution C G intron_variant BRCA-EU 14 39877946 39877946 single base substitution C G intron_variant BRCA-EU 14 39878013 39878013 single base substitution G A intron_variant BRCA-EU 14 39879727 39879727 single base substitution T A intron_variant BRCA-EU 14 39883527 39883527 single base substitution C G intron_variant BRCA-EU 14 39885750 39885750 single base substitution C G intron_variant BRCA-EU 14 39887203 39887203 single base substitution G A intron_variant BRCA-EU 14 39887895 39887895 single base substitution C T intron_variant BRCA-EU 14 39888735 39888735 single base substitution C A intron_variant BRCA-EU 14 39890381 39890381 single base substitution C G intron_variant BRCA-EU 14 39891721 39891721 single base substitution C G intron_variant BRCA-EU 14 39891789 39891789 single base substitution C T intron_variant BRCA-EU 14 39892001 39892001 single base substitution G A intron_variant BRCA-EU 14 39892049 39892049 single base substitution C T intron_variant BRCA-EU 14 39892579 39892579 single base substitution A T intron_variant BRCA-EU 14 39895255 39895255 single base substitution C T intron_variant BRCA-EU 14 39895503 39895503 single base substitution G T intron_variant BRCA-EU 14 39896016 39896016 single base substitution A C downstream_gene_variant BRCA-EU 14 39896016 39896016 single base substitution A C intron_variant BRCA-EU 14 39896383 39896383 deletion of <=200bp T - downstream_gene_variant BRCA-EU 14 39896383 39896383 deletion of <=200bp T - intron_variant BRCA-EU 14 39899348 39899348 single base substitution G C downstream_gene_variant BRCA-EU 14 39899348 39899348 single base substitution G C intron_variant BRCA-EU 14 39899578 39899578 insertion of <=200bp - AT downstream_gene_variant BRCA-EU 14 39899578 39899578 insertion of <=200bp - AT intron_variant BRCA-EU 14 39902074 39902074 single base substitution C G upstream_gene_variant BRCA-EU 14 39902636 39902636 single base substitution C A upstream_gene_variant BRCA-EU 14 39904486 39904486 single base substitution A G upstream_gene_variant BRCA-EU 14 39906406 39906406 insertion of <=200bp - T upstream_gene_variant BRCA-FR 14 39864766 39864766 single base substitution C G downstream_gene_variant BRCA-FR 14 39873036 39873036 single base substitution C T intron_variant BRCA-FR 14 39874529 39874529 single base substitution C G intron_variant BRCA-UK 14 39863285 39863285 single base substitution C T downstream_gene_variant BRCA-UK 14 39877946 39877946 single base substitution C G intron_variant BRCA-UK 14 39888735 39888735 single base substitution C A intron_variant BRCA-UK 14 39895503 39895503 single base substitution G T intron_variant BRCA-US 14 39870578 39870578 single base substitution C T intron_variant BRCA-US 14 39870578 39870578 single base substitution C T missense_variant D400N 1198G>A BRCA-US 14 39870683 39870683 single base substitution G A intron_variant BRCA-US 14 39870683 39870683 single base substitution G A stop_gained R365* 1093C>T BRCA-US 14 39870722 39870722 single base substitution C T intron_variant BRCA-US 14 39870722 39870722 single base substitution C T missense_variant D352N 1054G>A BRCA-US 14 39870860 39870860 single base substitution C T intron_variant BRCA-US 14 39870860 39870860 single base substitution C T missense_variant V306M 916G>A BRCA-US 14 39871049 39871049 single base substitution C T intron_variant BRCA-US 14 39871049 39871049 single base substitution C T missense_variant E243K 727G>A BRCA-US 14 39900893 39900893 single base substitution A C downstream_gene_variant BRCA-US 14 39900893 39900893 single base substitution A C synonymous_variant G158G 474T>G BRCA-US 14 39900893 39900893 single base substitution A C synonymous_variant G30G 90T>G BTCA-JP 14 39868711 39868711 deletion of <=200bp A - 3_prime_UTR_variant BTCA-JP 14 39868711 39868711 deletion of <=200bp A - downstream_gene_variant BTCA-JP 14 39871611 39871611 single base substitution A T intron_variant BTCA-JP 14 39871611 39871611 single base substitution A T missense_variant I235N 704T>A CESC-US 14 39868938 39868938 single base substitution C T missense_variant D484N 1450G>A CESC-US 14 39868938 39868938 single base substitution C T stop_retained_variant *90* 269G>A CESC-US 14 39870958 39870958 single base substitution G C intron_variant CESC-US 14 39870958 39870958 single base substitution G C missense_variant S273C 818C>G CLLE-ES 14 39892332 39892332 single base substitution A C intron_variant COAD-US 14 39870502 39870502 single base substitution A C intron_variant COAD-US 14 39870502 39870502 single base substitution A C missense_variant F425C 1274T>G COAD-US 14 39901157 39901157 single base substitution C A 5_prime_UTR_variant COAD-US 14 39901157 39901157 single base substitution C A synonymous_variant S70S 210G>T COAD-US 14 39901157 39901157 single base substitution C A upstream_gene_variant COCA-CN 14 39870337 39870337 single base substitution G A intron_variant COCA-CN 14 39871722 39871722 single base substitution G T intron_variant COCA-CN 14 39871722 39871722 single base substitution G T splice_region_variant COCA-CN 14 39900672 39900672 single base substitution T C downstream_gene_variant COCA-CN 14 39900672 39900672 single base substitution T C intron_variant COCA-CN 14 39900847 39900847 single base substitution G A downstream_gene_variant COCA-CN 14 39900847 39900847 single base substitution G A missense_variant L174F 520C>T COCA-CN 14 39900847 39900847 single base substitution G A missense_variant L46F 136C>T EOPC-DE 14 39887569 39887569 single base substitution A G intron_variant ESAD-UK 14 39865179 39865179 single base substitution G A downstream_gene_variant ESAD-UK 14 39868112 39868112 deletion of <=200bp T - 3_prime_UTR_variant ESAD-UK 14 39868112 39868112 deletion of <=200bp T - downstream_gene_variant ESAD-UK 14 39868569 39868569 single base substitution T C 3_prime_UTR_variant ESAD-UK 14 39868569 39868569 single base substitution T C downstream_gene_variant ESAD-UK 14 39868640 39868640 single base substitution T C 3_prime_UTR_variant ESAD-UK 14 39868640 39868640 single base substitution T C downstream_gene_variant ESAD-UK 14 39868752 39868752 single base substitution T C downstream_gene_variant ESAD-UK 14 39868752 39868752 single base substitution T C missense_variant R546G 1636A>G ESAD-UK 14 39868878 39868878 single base substitution C T 3_prime_UTR_variant ESAD-UK 14 39868878 39868878 single base substitution C T missense_variant D504N 1510G>A ESAD-UK 14 39869310 39869310 single base substitution T C intron_variant ESAD-UK 14 39871596 39871596 single base substitution A G intron_variant ESAD-UK 14 39873593 39873593 single base substitution C T intron_variant ESAD-UK 14 39874504 39874504 single base substitution T C intron_variant ESAD-UK 14 39874727 39874727 single base substitution G A intron_variant ESAD-UK 14 39876315 39876315 single base substitution T C intron_variant ESAD-UK 14 39881861 39881861 single base substitution T C intron_variant ESAD-UK 14 39882695 39882695 single base substitution C T intron_variant ESAD-UK 14 39882985 39882985 single base substitution T C intron_variant ESAD-UK 14 39883605 39883605 single base substitution A T intron_variant ESAD-UK 14 39884627 39884627 single base substitution T C intron_variant ESAD-UK 14 39887509 39887509 single base substitution C T intron_variant ESAD-UK 14 39888431 39888431 single base substitution A C intron_variant ESAD-UK 14 39888479 39888479 single base substitution G A intron_variant ESAD-UK 14 39894035 39894035 single base substitution G A intron_variant ESAD-UK 14 39894131 39894131 single base substitution C T intron_variant ESAD-UK 14 39894755 39894755 single base substitution T C intron_variant ESAD-UK 14 39894832 39894832 single base substitution T C intron_variant ESAD-UK 14 39895372 39895372 deletion of <=200bp T - intron_variant ESAD-UK 14 39895575 39895575 single base substitution C T intron_variant ESAD-UK 14 39896344 39896344 single base substitution G T downstream_gene_variant ESAD-UK 14 39896344 39896344 single base substitution G T intron_variant ESAD-UK 14 39902169 39902169 single base substitution C T upstream_gene_variant ESAD-UK 14 39903608 39903608 single base substitution T G upstream_gene_variant ESAD-UK 14 39904288 39904288 deletion of <=200bp A - upstream_gene_variant ESAD-UK 14 39905047 39905047 single base substitution C T upstream_gene_variant ESAD-UK 14 39905060 39905060 single base substitution A C upstream_gene_variant ESAD-UK 14 39905061 39905061 deletion of <=200bp T - upstream_gene_variant ESAD-UK 14 39905061 39905061 insertion of <=200bp - T upstream_gene_variant ESAD-UK 14 39906073 39906073 single base substitution T C upstream_gene_variant ESCA-CN 14 39871624 39871624 single base substitution C G intron_variant ESCA-CN 14 39871624 39871624 single base substitution C G missense_variant D231H 691G>C ESCA-CN 14 39871704 39871704 single base substitution T G intron_variant ESCA-CN 14 39871704 39871704 single base substitution T G missense_variant K204T 611A>C KIRP-US 14 39868808 39868808 single base substitution G A 3_prime_UTR_variant KIRP-US 14 39868808 39868808 single base substitution G A missense_variant A527V 1580C>T KIRP-US 14 39871674 39871674 single base substitution A G intron_variant KIRP-US 14 39871674 39871674 single base substitution A G missense_variant L214P 641T>C LAML-KR 14 39864450 39864450 single base substitution A G downstream_gene_variant LGG-US 14 39870639 39870639 single base substitution G A intron_variant LGG-US 14 39870639 39870639 single base substitution G A synonymous_variant I379I 1137C>T LICA-CN 14 39870593 39870593 single base substitution C G intron_variant LICA-CN 14 39870593 39870593 single base substitution C G missense_variant E395Q 1183G>C LICA-CN 14 39870601 39870601 single base substitution A G intron_variant LICA-CN 14 39870601 39870601 single base substitution A G missense_variant I392T 1175T>C LICA-FR 14 39889935 39889935 single base substitution C A intron_variant LICA-FR 14 39900997 39900997 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant LICA-FR 14 39900997 39900997 single base substitution G A missense_variant R124W 370C>T LINC-JP 14 39865632 39865632 single base substitution T C downstream_gene_variant LINC-JP 14 39868917 39868921 deletion of <=200bp TGACT - 3_prime_UTR_variant LINC-JP 14 39868917 39868921 deletion of <=200bp TGACT - frameshift_variant EVT489 LINC-JP 14 39871193 39871193 single base substitution C T intron_variant LINC-JP 14 39888598 39888598 single base substitution C T intron_variant LINC-JP 14 39890738 39890738 single base substitution T C intron_variant LINC-JP 14 39896401 39896401 single base substitution T G downstream_gene_variant LINC-JP 14 39896401 39896401 single base substitution T G intron_variant LINC-JP 14 39904446 39904446 single base substitution C T upstream_gene_variant LIRI-JP 14 39869874 39869874 single base substitution T C intron_variant LIRI-JP 14 39870806 39870806 single base substitution T C intron_variant LIRI-JP 14 39870806 39870806 single base substitution T C missense_variant R324G 970A>G LIRI-JP 14 39872995 39872995 single base substitution A C intron_variant LIRI-JP 14 39873326 39873326 single base substitution A G intron_variant LIRI-JP 14 39877338 39877338 single base substitution A G intron_variant LIRI-JP 14 39877687 39877687 single base substitution T C intron_variant LIRI-JP 14 39877900 39877900 single base substitution T A intron_variant LIRI-JP 14 39879518 39879518 single base substitution T C intron_variant LIRI-JP 14 39881586 39881586 single base substitution T C intron_variant LIRI-JP 14 39881618 39881618 single base substitution T C intron_variant LIRI-JP 14 39885050 39885050 single base substitution T C intron_variant LIRI-JP 14 39886251 39886251 single base substitution T G intron_variant LIRI-JP 14 39886646 39886646 single base substitution A C intron_variant LIRI-JP 14 39886924 39886924 single base substitution G A intron_variant LIRI-JP 14 39887173 39887173 single base substitution C G intron_variant LIRI-JP 14 39890352 39890352 single base substitution G T intron_variant LIRI-JP 14 39890862 39890862 single base substitution T C intron_variant LIRI-JP 14 39892892 39892892 single base substitution A G intron_variant LIRI-JP 14 39893816 39893816 single base substitution G T intron_variant LIRI-JP 14 39893861 39893861 single base substitution T C intron_variant LIRI-JP 14 39895907 39895907 single base substitution G A intron_variant LIRI-JP 14 39896111 39896111 single base substitution T G downstream_gene_variant LIRI-JP 14 39896111 39896111 single base substitution T G intron_variant LIRI-JP 14 39896380 39896380 single base substitution A T downstream_gene_variant LIRI-JP 14 39896380 39896380 single base substitution A T intron_variant LIRI-JP 14 39897317 39897317 single base substitution C T downstream_gene_variant LIRI-JP 14 39897317 39897317 single base substitution C T intron_variant LIRI-JP 14 39903202 39903202 single base substitution A G upstream_gene_variant LIRI-JP 14 39904012 39904012 single base substitution A G upstream_gene_variant LIRI-JP 14 39905650 39905650 single base substitution T C upstream_gene_variant LUSC-KR 14 39863171 39863171 single base substitution C T downstream_gene_variant LUSC-KR 14 39864450 39864450 single base substitution A G downstream_gene_variant LUSC-KR 14 39868094 39868094 single base substitution C T 3_prime_UTR_variant LUSC-KR 14 39868094 39868094 single base substitution C T downstream_gene_variant LUSC-KR 14 39868771 39868771 single base substitution T A 3_prime_UTR_variant LUSC-KR 14 39868771 39868771 single base substitution T A missense_variant E539D 1617A>T LUSC-KR 14 39871230 39871230 single base substitution T A intron_variant LUSC-KR 14 39871269 39871269 single base substitution A G intron_variant LUSC-KR 14 39874494 39874494 single base substitution G A intron_variant LUSC-KR 14 39879722 39879722 single base substitution C T intron_variant LUSC-KR 14 39883671 39883671 single base substitution C G intron_variant LUSC-KR 14 39891043 39891043 single base substitution T C intron_variant LUSC-KR 14 39891470 39891470 single base substitution T C intron_variant LUSC-KR 14 39892698 39892698 single base substitution C T intron_variant LUSC-KR 14 39905541 39905541 single base substitution A G upstream_gene_variant LUSC-US 14 39900916 39900916 single base substitution C G downstream_gene_variant LUSC-US 14 39900916 39900916 single base substitution C G missense_variant G151R 451G>C LUSC-US 14 39900916 39900916 single base substitution C G missense_variant G23R 67G>C MALY-DE 14 39876499 39876500 deletion of <=200bp TG - intron_variant MALY-DE 14 39879158 39879158 single base substitution T A intron_variant MALY-DE 14 39885184 39885184 deletion of <=200bp T - intron_variant MALY-DE 14 39885248 39885251 deletion of <=200bp TATT - intron_variant MALY-DE 14 39887969 39887969 single base substitution A C intron_variant MALY-DE 14 39890079 39890079 single base substitution T G intron_variant MALY-DE 14 39897263 39897263 single base substitution G C downstream_gene_variant MALY-DE 14 39897263 39897263 single base substitution G C intron_variant MALY-DE 14 39899578 39899579 deletion of <=200bp AT - downstream_gene_variant MALY-DE 14 39899578 39899579 deletion of <=200bp AT - intron_variant MALY-DE 14 39902581 39902581 single base substitution T C upstream_gene_variant MELA-AU 14 39863072 39863072 single base substitution C T downstream_gene_variant MELA-AU 14 39863480 39863480 single base substitution G A downstream_gene_variant MELA-AU 14 39865856 39865856 single base substitution A G downstream_gene_variant MELA-AU 14 39866779 39866779 single base substitution A G downstream_gene_variant MELA-AU 14 39868219 39868219 single base substitution C T 3_prime_UTR_variant MELA-AU 14 39868219 39868219 single base substitution C T downstream_gene_variant MELA-AU 14 39868916 39868916 single base substitution G A 3_prime_UTR_variant MELA-AU 14 39868916 39868916 single base substitution G A missense_variant T491I 1472C>T MELA-AU 14 39869110 39869110 single base substitution C T intron_variant MELA-AU 14 39869918 39869918 single base substitution T C intron_variant MELA-AU 14 39871071 39871071 single base substitution A C intron_variant MELA-AU 14 39871071 39871071 single base substitution A C splice_region_variant MELA-AU 14 39871561 39871561 single base substitution A G intron_variant MELA-AU 14 39871847 39871847 single base substitution A G intron_variant MELA-AU 14 39872366 39872366 single base substitution T C intron_variant MELA-AU 14 39872435 39872435 single base substitution A G intron_variant MELA-AU 14 39872730 39872730 single base substitution C T intron_variant MELA-AU 14 39872835 39872835 single base substitution T A intron_variant MELA-AU 14 39873279 39873279 single base substitution C T intron_variant MELA-AU 14 39873281 39873281 single base substitution C T intron_variant MELA-AU 14 39873570 39873570 single base substitution G A intron_variant MELA-AU 14 39873685 39873685 single base substitution C T intron_variant MELA-AU 14 39873800 39873800 single base substitution G A intron_variant MELA-AU 14 39874286 39874286 single base substitution G A intron_variant MELA-AU 14 39876085 39876085 single base substitution G A intron_variant MELA-AU 14 39876255 39876255 single base substitution G A intron_variant MELA-AU 14 39878877 39878877 single base substitution G A intron_variant MELA-AU 14 39878963 39878963 single base substitution A T intron_variant MELA-AU 14 39879782 39879782 single base substitution G A intron_variant MELA-AU 14 39880394 39880394 single base substitution G A intron_variant MELA-AU 14 39881556 39881556 single base substitution A T intron_variant MELA-AU 14 39881728 39881728 single base substitution G A intron_variant MELA-AU 14 39882168 39882168 single base substitution G A intron_variant MELA-AU 14 39882356 39882356 single base substitution A T intron_variant MELA-AU 14 39883388 39883388 single base substitution C T intron_variant MELA-AU 14 39884009 39884009 single base substitution G A intron_variant MELA-AU 14 39884512 39884512 single base substitution G A intron_variant MELA-AU 14 39885625 39885625 single base substitution G A intron_variant MELA-AU 14 39885899 39885899 single base substitution C T intron_variant MELA-AU 14 39885997 39885997 single base substitution G A intron_variant MELA-AU 14 39887331 39887331 single base substitution G A intron_variant MELA-AU 14 39887525 39887525 single base substitution C T intron_variant MELA-AU 14 39888816 39888816 single base substitution A T intron_variant MELA-AU 14 39889576 39889576 single base substitution G A intron_variant MELA-AU 14 39889708 39889708 single base substitution G A intron_variant MELA-AU 14 39890875 39890875 single base substitution G A intron_variant MELA-AU 14 39891124 39891124 single base substitution C T intron_variant MELA-AU 14 39891330 39891330 single base substitution C T intron_variant MELA-AU 14 39893288 39893288 single base substitution A T intron_variant MELA-AU 14 39893380 39893380 single base substitution T G intron_variant MELA-AU 14 39893905 39893905 single base substitution G A intron_variant MELA-AU 14 39894539 39894539 single base substitution G A intron_variant MELA-AU 14 39894747 39894747 single base substitution C T intron_variant MELA-AU 14 39895674 39895674 single base substitution A T intron_variant MELA-AU 14 39895751 39895751 single base substitution C A intron_variant MELA-AU 14 39895752 39895752 single base substitution T C intron_variant MELA-AU 14 39896093 39896093 single base substitution T C downstream_gene_variant MELA-AU 14 39896093 39896093 single base substitution T C intron_variant MELA-AU 14 39896135 39896135 single base substitution T A downstream_gene_variant MELA-AU 14 39896135 39896135 single base substitution T A intron_variant MELA-AU 14 39896137 39896137 single base substitution C T downstream_gene_variant MELA-AU 14 39896137 39896137 single base substitution C T intron_variant MELA-AU 14 39897624 39897624 single base substitution G A downstream_gene_variant MELA-AU 14 39897624 39897624 single base substitution G A intron_variant MELA-AU 14 39899806 39899806 single base substitution G A downstream_gene_variant MELA-AU 14 39899806 39899806 single base substitution G A intron_variant MELA-AU 14 39900184 39900185 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU 14 39900184 39900185 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 14 39901350 39901350 single base substitution G T intron_variant MELA-AU 14 39901350 39901350 single base substitution G T stop_gained S6* 17C>A MELA-AU 14 39901350 39901350 single base substitution G T upstream_gene_variant MELA-AU 14 39901751 39901751 single base substitution C T upstream_gene_variant MELA-AU 14 39903537 39903537 single base substitution C T upstream_gene_variant MELA-AU 14 39904059 39904059 single base substitution C T upstream_gene_variant MELA-AU 14 39904399 39904399 single base substitution G A upstream_gene_variant MELA-AU 14 39904510 39904510 single base substitution G A upstream_gene_variant MELA-AU 14 39904789 39904789 single base substitution C T upstream_gene_variant MELA-AU 14 39905074 39905074 single base substitution C T upstream_gene_variant MELA-AU 14 39905096 39905096 single base substitution G A upstream_gene_variant MELA-AU 14 39905128 39905128 single base substitution T C upstream_gene_variant MELA-AU 14 39905331 39905331 single base substitution C T upstream_gene_variant MELA-AU 14 39905339 39905339 single base substitution G A upstream_gene_variant MELA-AU 14 39905416 39905416 single base substitution C T upstream_gene_variant MELA-AU 14 39905529 39905529 single base substitution G A upstream_gene_variant MELA-AU 14 39905774 39905774 single base substitution C T upstream_gene_variant MELA-AU 14 39905821 39905821 single base substitution G A upstream_gene_variant MELA-AU 14 39906365 39906365 single base substitution C G upstream_gene_variant MELA-AU 14 39906370 39906370 single base substitution C T upstream_gene_variant MELA-AU 14 39906519 39906519 single base substitution C T upstream_gene_variant MELA-AU 14 39906567 39906567 single base substitution T C upstream_gene_variant MELA-AU 14 39906617 39906617 single base substitution C T upstream_gene_variant ORCA-IN 14 39863567 39863567 single base substitution T C downstream_gene_variant ORCA-IN 14 39871640 39871640 single base substitution G A intron_variant ORCA-IN 14 39871640 39871640 single base substitution G A synonymous_variant L225L 675C>T ORCA-IN 14 39871696 39871696 single base substitution G T intron_variant ORCA-IN 14 39871696 39871696 single base substitution G T missense_variant L207I 619C>A OV-AU 14 39893390 39893390 single base substitution G C intron_variant OV-AU 14 39894609 39894609 single base substitution A G intron_variant OV-AU 14 39901479 39901479 single base substitution C G 5_prime_UTR_variant OV-AU 14 39901479 39901479 single base substitution C G upstream_gene_variant PACA-AU 14 39865125 39865125 single base substitution G C downstream_gene_variant PACA-AU 14 39870942 39870942 single base substitution G T intron_variant PACA-AU 14 39870942 39870942 single base substitution G T missense_variant N278K 834C>A PACA-AU 14 39877256 39877256 single base substitution C A intron_variant PACA-AU 14 39885564 39885564 single base substitution T A intron_variant PACA-AU 14 39902426 39902426 single base substitution T A upstream_gene_variant PACA-AU 14 39906442 39906442 deletion of <=200bp A - upstream_gene_variant PACA-CA 14 39865455 39865455 single base substitution A C downstream_gene_variant PACA-CA 14 39867268 39867268 insertion of <=200bp - T 3_prime_UTR_variant PACA-CA 14 39867268 39867268 insertion of <=200bp - T downstream_gene_variant PACA-CA 14 39868448 39868448 single base substitution T C 3_prime_UTR_variant PACA-CA 14 39868448 39868448 single base substitution T C downstream_gene_variant PACA-CA 14 39869738 39869738 single base substitution C T intron_variant PACA-CA 14 39870445 39870445 single base substitution C T intron_variant PACA-CA 14 39870445 39870445 single base substitution C T missense_variant R444Q 1331G>A PACA-CA 14 39880892 39880892 single base substitution A T intron_variant PACA-CA 14 39881036 39881036 single base substitution T C intron_variant PACA-CA 14 39884520 39884520 single base substitution C A intron_variant PACA-CA 14 39885143 39885143 single base substitution T C intron_variant PACA-CA 14 39887469 39887469 single base substitution G A intron_variant PACA-CA 14 39887872 39887872 single base substitution G A intron_variant PACA-CA 14 39887984 39887984 single base substitution A C intron_variant PACA-CA 14 39890436 39890436 single base substitution T C intron_variant PACA-CA 14 39891030 39891030 single base substitution G A intron_variant PACA-CA 14 39895417 39895417 single base substitution C A intron_variant PACA-CA 14 39896532 39896532 single base substitution A G downstream_gene_variant PACA-CA 14 39896532 39896532 single base substitution A G intron_variant PACA-CA 14 39897033 39897033 single base substitution T G downstream_gene_variant PACA-CA 14 39897033 39897033 single base substitution T G intron_variant PACA-CA 14 39903850 39903850 single base substitution T C upstream_gene_variant PAEN-AU 14 39905206 39905206 single base substitution T C upstream_gene_variant PAEN-IT 14 39878684 39878684 single base substitution C A intron_variant PBCA-DE 14 39879131 39879131 insertion of <=200bp - T intron_variant PBCA-DE 14 39886037 39886037 insertion of <=200bp - T intron_variant PBCA-DE 14 39889895 39889895 insertion of <=200bp - A intron_variant PBCA-DE 14 39891722 39891722 insertion of <=200bp - A intron_variant PBCA-DE 14 39898917 39898917 single base substitution A T downstream_gene_variant PBCA-DE 14 39898917 39898917 single base substitution A T intron_variant PRAD-CA 14 39885471 39885471 single base substitution C T intron_variant PRAD-CA 14 39900330 39900330 single base substitution A G downstream_gene_variant PRAD-CA 14 39900330 39900330 single base substitution A G intron_variant PRAD-CA 14 39901791 39901791 single base substitution G T upstream_gene_variant PRAD-UK 14 39864789 39864789 single base substitution T C downstream_gene_variant PRAD-UK 14 39880097 39880098 deletion of <=200bp TT - intron_variant PRAD-UK 14 39888058 39888058 single base substitution T C intron_variant PRAD-UK 14 39894810 39894810 single base substitution T C intron_variant PRAD-UK 14 39897474 39897474 single base substitution A C downstream_gene_variant PRAD-UK 14 39897474 39897474 single base substitution A C intron_variant PRAD-UK 14 39902269 39902269 single base substitution T C upstream_gene_variant PRAD-UK 14 39904423 39904423 single base substitution A G upstream_gene_variant RECA-EU 14 39869064 39869064 single base substitution C T intron_variant RECA-EU 14 39875306 39875306 single base substitution T A intron_variant SKCA-BR 14 39865122 39865122 insertion of <=200bp - GT downstream_gene_variant SKCA-BR 14 39867658 39867658 single base substitution G T 3_prime_UTR_variant SKCA-BR 14 39867658 39867658 single base substitution G T downstream_gene_variant SKCA-BR 14 39867669 39867669 single base substitution C T 3_prime_UTR_variant SKCA-BR 14 39867669 39867669 single base substitution C T downstream_gene_variant SKCA-BR 14 39873445 39873445 single base substitution G A intron_variant SKCA-BR 14 39875644 39875644 single base substitution G A intron_variant SKCA-BR 14 39879326 39879326 single base substitution G A intron_variant SKCA-BR 14 39879781 39879781 single base substitution C T intron_variant SKCA-BR 14 39886515 39886515 single base substitution G A intron_variant SKCA-BR 14 39886740 39886740 insertion of <=200bp - AT intron_variant SKCA-BR 14 39888300 39888300 single base substitution C A intron_variant SKCA-BR 14 39889812 39889812 single base substitution G A intron_variant SKCA-BR 14 39895364 39895364 single base substitution C T intron_variant SKCA-BR 14 39895602 39895602 single base substitution C T intron_variant SKCA-BR 14 39901703 39901703 single base substitution G A 5_prime_UTR_variant SKCA-BR 14 39901703 39901703 single base substitution G A upstream_gene_variant SKCA-BR 14 39901703 39901703 single base substitution G T 5_prime_UTR_variant SKCA-BR 14 39901703 39901703 single base substitution G T upstream_gene_variant SKCA-BR 14 39904731 39904731 single base substitution T C upstream_gene_variant SKCA-BR 14 39906615 39906615 single base substitution T C upstream_gene_variant SKCM-US 14 39868916 39868916 single base substitution G A 3_prime_UTR_variant SKCM-US 14 39868916 39868916 single base substitution G A missense_variant T491I 1472C>T SKCM-US 14 39870725 39870725 single base substitution G A intron_variant SKCM-US 14 39870725 39870725 single base substitution G A synonymous_variant L351L 1051C>T SKCM-US 14 39870734 39870734 single base substitution G T intron_variant SKCM-US 14 39870734 39870734 single base substitution G T missense_variant H348N 1042C>A STAD-US 14 39870564 39870564 single base substitution A G intron_variant STAD-US 14 39870564 39870564 single base substitution A G synonymous_variant T404T 1212T>C STAD-US 14 39870682 39870682 single base substitution C T intron_variant STAD-US 14 39870682 39870682 single base substitution C T missense_variant R365Q 1094G>A STAD-US 14 39870866 39870866 single base substitution G A intron_variant STAD-US 14 39870866 39870866 single base substitution G A stop_gained R304* 910C>T STAD-US 14 39871611 39871611 single base substitution A T intron_variant STAD-US 14 39871611 39871611 single base substitution A T missense_variant I235N 704T>A STAD-US 14 39871612 39871612 insertion of <=200bp - T frameshift_variant I235N? STAD-US 14 39871612 39871612 insertion of <=200bp - T intron_variant STAD-US 14 39871660 39871660 single base substitution T G intron_variant STAD-US 14 39871660 39871660 single base substitution T G missense_variant S219R 655A>C THCA-SA 14 39868646 39868646 single base substitution C A 3_prime_UTR_variant THCA-SA 14 39868646 39868646 single base substitution C A downstream_gene_variant UCEC-US 14 39870664 39870664 single base substitution C T intron_variant UCEC-US 14 39870664 39870664 single base substitution C T missense_variant R371Q 1112G>A

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand I-01 COSM4767058 c.968C>G p.A323G Substitution - Missense 14:39401604-39401604 - OSCC-GB_00740111 COSM4891068 c.619C>A p.L207I Substitution - Missense 14:39402492-39402492 - SC_9031 COSM5565568 c.91C>T p.R31W Substitution - Missense 14:39432072-39432072 - TCGA-B6-A408-01 COSM3814811 c.474T>G p.G158G Substitution - coding silent 14:39431689-39431689 - 2492730 COSM5728491 c.261C>T p.D87D Substitution - coding silent 14:39431902-39431902 - 2250206 COSM5030760 c.100_108delCAGCTGCGA p.Q34_R36delQLR Deletion - In frame 14:39432055-39432063 - MO_1012 COSM5567901 c.802T>C p.S268P Substitution - Missense 14:39401770-39401770 - CHEWS009 COSM4577859 c.500A>C p.E167A Substitution - Missense 14:39431663-39431663 - KM12 COSM2196971 c.548G>T p.R183L Substitution - Missense 14:39431615-39431615 - 91827 COSM330306 c.531T>C p.R177R Substitution - coding silent 14:39431632-39431632 - HCC139T COSM5823111 c.1175T>C p.I392T Substitution - Missense 14:39401397-39401397 - SC_9093 COSM5549961 c.1411G>A p.A471T Substitution - Missense 14:39399773-39399773 - LUAD-S01373 COSM388139 c.1275T>A p.F425L Substitution - Missense 14:39401297-39401297 - HDC82 COSM4636615 c.28C>T p.P10S Substitution - Missense 14:39432135-39432135 - TCGA-BR-6452-01 COSM4050821 c.655A>C p.S219R Substitution - Missense 14:39402456-39402456 - PCSI_0083_Pa_X COSM3377405 c.1331G>A p.R444Q Substitution - Missense 14:39401241-39401241 - TCGA-LP-A5U2-01 COSM4833818 c.818C>G p.S273C Substitution - Missense 14:39401754-39401754 - TCGA-BQ-5877-01 COSM3987645 c.1580C>T p.A527V Substitution - Missense 14:39399604-39399604 - PCSI_0083_Pa_P_526 COSM3377405 c.1331G>A p.R444Q Substitution - Missense 14:39401241-39401241 - RKO COSM4647760 c.892A>G p.T298A Substitution - Missense 14:39401680-39401680 - 8068548 COSM3771799 c.834C>A p.N278K Substitution - Missense 14:39401738-39401738 - 587350 COSM1206829 c.1535A>C p.N512T Substitution - Missense 14:39399649-39399649 - SS6003121 COSM3980108 c.1636A>G p.R546G Substitution - Missense 14:39399548-39399548 - SH-0622 COSM4610958 c.703delA p.I235fs*12 Deletion - Frameshift 14:39402408-39402408 - TCGA-BR-4362-01 COSM4050817 c.1212T>C p.T404T Substitution - coding silent 14:39401360-39401360 - PT19_1 COSM5899663 c.1297G>T p.D433Y Substitution - Missense 14:39401275-39401275 - TCGA-BR-8680-01 COSM4050818 c.1094G>A p.R365Q Substitution - Missense 14:39401478-39401478 - 259610 COSM3725434 c.549C>T p.R183R Substitution - coding silent 14:39431614-39431614 - BCM375T COSM4950984 c.370C>T p.R124W Substitution - Missense 14:39431793-39431793 - RK288_C01 COSM4780552 c.970A>G p.R324G Substitution - Missense 14:39401602-39401602 - C135 COSM4610958 c.703delA p.I235fs*12 Deletion - Frameshift 14:39402408-39402408 - LUAD-RT-S01777 COSM381927 c.947G>T p.C316F Substitution - Missense 14:39401625-39401625 - WSU-HN6 COSM4602371 c.259G>A p.D87N Substitution - Missense 14:39431904-39431904 - TCGA-BH-A2L8-01 COSM3814807 c.1198G>A p.D400N Substitution - Missense 14:39401374-39401374 - TCGA-BR-A4QL-01 COSM4050820 c.704T>A p.I235N Substitution - Missense 14:39402407-39402407 - TCGA-D3-A51K-06 COSM3496020 c.1042C>A p.H348N Substitution - Missense 14:39401530-39401530 - ZZUFHECRKL-G045T COSM5437876 c.611A>C p.K204T Substitution - Missense 14:39402500-39402500 - 103T COSM1237783 c.1235A>T p.D412V Substitution - Missense 14:39401337-39401337 - TCGA-BR-8680-01 COSM4050819 c.910C>T p.R304* Substitution - Nonsense 14:39401662-39401662 - 10-P083 COSM4577860 c.451G>A p.G151S Substitution - Missense 14:39431712-39431712 - PT16_1 COSM5898481 c.1397-3C>T p.? Unknown 14:39399790-39399790 - TCGA-AA-3510-01 COSM1369792 c.1274T>G p.F425C Substitution - Missense 14:39401298-39401298 - LIM2405 COSM4641866 c.235A>G p.I79V Substitution - Missense 14:39431928-39431928 - PTC-77C COSM3753961 c.210G>T p.S70S Substitution - coding silent 14:39431953-39431953 - sysucc-1247T COSM5764669 c.520C>T p.L174F Substitution - Missense 14:39431643-39431643 - CSCC-44-T COSM4524700 c.1288G>A p.D430N Substitution - Missense 14:39401284-39401284 - TCGA-D8-A27R-01 COSM1477565 c.1054G>A p.D352N Substitution - Missense 14:39401518-39401518 - XHDG22 COSM4769020 c.1183G>C p.E395Q Substitution - Missense 14:39401389-39401389 - TCGA-CZ-5466-01 COSM469957 c.638T>C p.V213A Substitution - Missense 14:39402473-39402473 - TCGA-EE-A3AF-06 COSM3496019 c.1051C>T p.L351L Substitution - coding silent 14:39401521-39401521 - TCGA-BH-A0HF-01 COSM3814809 c.916G>A p.V306M Substitution - Missense 14:39401656-39401656 - TCGA-13-2061-01 COSM1323497 c.375G>T p.L125L Substitution - coding silent 14:39431788-39431788 - TCGA-B5-A0K6-01 COSM955696 c.1112G>A p.R371Q Substitution - Missense 14:39401460-39401460 - TCGA-F4-6855-01 COSM3753961 c.210G>T p.S70S Substitution - coding silent 14:39431953-39431953 - TCGA-60-2722-01 COSM698650 c.451G>C p.G151R Substitution - Missense 14:39431712-39431712 - BCM375T COSM4950984 c.370C>T p.R124W Substitution - Missense 14:39431793-39431793 - J11_T COSM3956027 c.1617A>T p.E539D Substitution - Missense 14:39399567-39399567 - HCC7T COSM1607676 c.1467_1471delAGTCA p.E489fs*6 Deletion - Frameshift 14:39399713-39399717 - 10-P1058 COSM4577857 c.1594G>A p.E532K Substitution - Missense 14:39399590-39399590 - PCSI_0083_Pa_P COSM3377405 c.1331G>A p.R444Q Substitution - Missense 14:39401241-39401241 - TCGA-C5-A1MK-01 COSM4826877 c.1450G>A p.D484N Substitution - Missense 14:39399734-39399734 - TCGA-B1-A47M-01 COSM4414702 c.641T>C p.L214P Substitution - Missense 14:39402470-39402470 - Pat_06_A COSM5848103 c.1598C>A p.S533* Substitution - Nonsense 14:39399586-39399586 - TCGA-HT-7855-01 COSM3968811 c.1137C>T p.I379I Substitution - coding silent 14:39401435-39401435 - Pat_16_A COSM5848102 c.1668G>C p.*556Y Nonstop extension 14:39399516-39399516 - TCGA-A8-A09Z-01 COSM3814808 c.1093C>T p.R365* Substitution - Nonsense 14:39401479-39401479 - 544 COSM5612588 c.1170C>T p.P390P Substitution - coding silent 14:39401402-39401402 - TCGA-EE-A29L-06 COSM3496018 c.1472C>T p.T491I Substitution - Missense 14:39399712-39399712 - TCGA-D8-A27G-01 COSM3814810 c.727G>A p.E243K Substitution - Missense 14:39401845-39401845 - BD57T COSM4050820 c.704T>A p.I235N Substitution - Missense 14:39402407-39402407 - TTC466 COSM4577858 c.973G>T p.V325F Substitution - Missense 14:39401599-39401599 - ESCC-038T COSM3936512 c.691G>C p.D231H Substitution - Missense 14:39402420-39402420 - T228 COSM4683980 c.1575delG p.W525fs*>31 Deletion - Frameshift 14:39399609-39399609 - OSCC-GB_01220111 COSM5955060 c.675C>T p.L225L Substitution - coding silent 14:39402436-39402436 - HCC111T COSM4769020 c.1183G>C p.E395Q Substitution - Missense 14:39401389-39401389 - TCGA-DK-A1A3-01 COSM416691 c.1531C>T p.H511Y Substitution - Missense 14:39399653-39399653 - Pat_16_B COSM5848102 c.1668G>C p.*556Y Nonstop extension 14:39399516-39399516 - PTC-70C COSM3753961 c.210G>T p.S70S Substitution - coding silent 14:39431953-39431953 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.146623;Hs.146628;Hs.146629;Hs.146632 14q21.1 609103

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer AATTCTATAAGGAAAAC - SpliceAcceptorDeletion . c.711-13_714delGTTTTCCTTATAGAATT 14 39871062 HNSC A C IntronicSNV . c.599+8436T>G 14 39892332 CLL C G Missense p.D412H c.1234G>C 14 39870542 LUAD C G Missense p.G151R c.451G>C 14 39900916 LUSC C T Missense p.D352N c.1054G>A 14 39870722 BRCA C T Missense p.R371Q c.1112G>A 14 39870664 UCEC C T Nonsense p.W108* c.324G>A 14 39901043 CM G A Missense p.H511Y c.1531C>T 14 39868857 BLCA G A Missense p.T491I c.1472C>T 14 39868916 CM G A Synonymous p.D498D c.1494C>T 14 39868894 CM G A Synonymous p.L351L c.1051C>T 14 39870725 CM G A Synonymous p.L388L c.1162C>T 14 39870614 CM G T Synonymous p.R371R c.1111C>A 14 39870665 LUAD T A Missense p.H342L c.1025A>T 14 39870751 LUAD