PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus DDX3X FBXO33 16797541 mint,intact exp G GP G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G C1QBP FBXO33 16797541 mint,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G YBX1 FBXO33 16797541 hprd,biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSP90AB1 FBXO33 16797541 mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CUL1 FBXO33 16797541,21145461 biogrid,mint,intact exp GP G G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G RBX1 FBXO33 16797541 mint,intact exp G G G G G GP G GP G G G G GP G G G GP G GP G GP GP G G G G G GP G IPO5 FBXO33 16797541 mint,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G HSPA9 FBXO33 16797541 mint,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SKP1 FBXO33 16797541, 25402006, 23023127 mint,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PVRL1 FBXO33 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G G GP G GP GP G FBXO31 FBXO33 23023127 pred GP GP G P GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TFAP2A FBXO33 25402006 pred GP G G G G G G G G GP G G G G G G G G GP G G G G G G G ANKS1B FBXO33 23023127 pred P P G P GP G P P G GP P P P G GP GP GP P G P P GP P GP P GP GP FBXO33 NPTN 23023127 pred G G G G G GP G G GP G GP GP G G G GP GP GP G G G G GP G GP G GP G G SCN2B FBXO33 23023127 pred P P G P GP G GP GP G P P P P P GP P P G P P P GP GP P P P CTCF FBXO33 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HABP4 FBXO33 25402006 pred G GP G G G GP G G G G GP GP GP G G GP GP G GP G G G GP GP G GP GP G RBBP6 FBXO33 25402006 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G GP G GP G GP GP GP GP G KBTBD11 FBXO33 23023127 pred GP GP G G GP GP G P GP G GP GP GP GP G GP GP P P G P GP P GP GP GP P P G FBXO33 SCN3B 23023127 pred P GP G P GP G P G P P G P GP G P G P G P P P FBXO33 CGREF1 23023127 pred P P G P GP P P G P P P P GP GP GP P P GP P GP P GP P TYRO3 FBXO33 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PPM1G FBXO33 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NEGR1 FBXO33 23023127 pred G GP G P GP G GP G G P P GP G G G GP G P G GP GP P G GP P FBXO33 REPS2 23023127 pred G G G G GP GP G GP G GP GP GP GP GP GP GP GP G GP GP G P GP P GP P FBXO33 SPOCK3 23023127 pred G G G G G G FBXO33 ICAM5 23023127 pred G G G GP G GP G SCN1B FBXO33 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MYCBP2 FBXO33 23023127 pred G GP G G G GP G GP GP G G G GP GP G GP GP G GP G G GP G G GP G G GP G FBXO33 VSTM2L 23023127 pred P G GP G GP GP G P P GP P P GP P G G P P P P G GP P FBXO33 ZBTB44 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CRH FBXO33 23023127 pred P P G G GP GP P P G P P P P GP P GP GP P P GP P P P G FBXO33 CREBRF 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FBXO33 CADM2 23023127 pred G P GP G GP G P P P P GP P G P P P P P P P FOXP2 FBXO33 23023127 pred GP GP G P GP G GP GP G GP GP GP P G GP GP GP GP G GP GP GP GP GP GP GP P G SRSF9 FBXO33 25402006 pred P P P P P P P P P P P P P P P P P P P P P CD8A FBXO33 23023127 pred G G G G GP G G G G G G G GP GP G G G G G G G G G G G GP G G G BAG4 FBXO33 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CD200 FBXO33 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP GP GP G GP GP GP P GP GP GP P G PURA FBXO33 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P67809 Q7Z6M2 affinity chromatography technology 16797541 physical association X 2 P67809 Q7Z6M2 affinity chromatography technology 16797541 physical association X 2 P67809 Q7Z6M2 enzymatic study 16797541 direct interaction X 2 P0CG48 Q7Z6M2 affinity chromatography technology 21139048 physical association X 2 A0A090N7U0 Q7Z6M2 affinity chromatography technology 21145461 physical association X 2 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 P67809 Q7Z6M2 in vivo 16797541 - X 2 P67809 Q7Z6M2 in vitro 16797541 - X 2 P67809 Q7Z6M2 in vitro 16797541 - X 2 P67809 Q7Z6M2 in vivo 16797541 - X 2 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 Q7Z6M2 in vivo 16797541 - C 4 O00571 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 P62877 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 P67809 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 P67809 Q7Z6M2 pull down 16797541 physical association X 2 P67809 Q7Z6M2 pull down 16797541 physical association X 2 P67809 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 P67809 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 Q7Z6M2 P38646 anti tag coimmunoprecipitation 16797541 physical association X 2 A0A024RD80 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 A0A090N7U0 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 O00410 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 P63208 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2 Q07021 Q7Z6M2 anti tag coimmunoprecipitation 16797541 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q7Z6M2 O00410 FBXO33 IPO5 0.21 16797541 Q7Z6M2 O00571 FBXO33 DDX3X 0.21 16797541 Q7Z6M2 P08238 FBXO33 HSP90AB1 0.21 16797541 Q7Z6M2 P38646 FBXO33 HSPA9 0.21 16797541 Q7Z6M2 P62877 FBXO33 RBX1 0.21 16797541 Q7Z6M2 Q07021 FBXO33 C1QBP 0.21 16797541 Q7Z6M2 Q13616 FBXO33 CUL1 0.309 16797541,21145461 Q7Z6M2 P63208 FBXO33 SKP1 0.309 16797541,27705803 Q7Z6M2 P67809 FBXO33 YBX1 0.731 16797541