Disease associated variation - ClinVar Allele ID Type Name RS#dbSNP Phenotype IDs Chromosome Start Stop Reference Alternate 259325 single nucleotide variant NM_017583.5(TRIM44):c.463G>A (p.Gly155Arg) 886039241 MedGen:CN238677,OMIM:617142 11 35663574 35663574 G A 259325 single nucleotide variant NM_017583.5(TRIM44):c.463G>A (p.Gly155Arg) 886039241 MedGen:CN238677,OMIM:617142 11 35685122 35685122 G A

Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 11 35697846 rs7103188 A G rs7103188 5.41E-05 Cognitive test performance HPOID:0100543 DOID:1561 A intron GWASdb_trait 11 35700997 rs16927845 G A rs16927845 5.85E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 11 35701236 rs7928794 A C rs7928794 8.00E-06 Response to antipsychotic therapy (extrapyramidal side effects) HPOID:0000709 DOID:5419 A intron GWASdb_trait 11 35747375 rs12222279 A G rs12222279 2.07E-04 Smoking quantity HPOID:0000707 DOID:0050742 A intron GWASdb_trait 11 35753511 rs11033260 A G rs11033260 1.73E-04 Type 2 diabetes HPOID:0005978 DOID:9352 A intron GWASdb_trait 11 35775926 rs11033265 G A rs11033265 1.54E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 11 35788133 rs10836443 G A rs10836443 1.42E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 11 35802040 rs2147094 T C rs2147094 7.01E-04 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 G intron GWASdb_trait 11 35813921 rs2938188 T G rs2938188 5.22E-04 Lymphocyte counts HPOID:0004332|HPOID:0002665 DOID:2841|DOID:1240|DOID:0060058|DOID:614|DOID:1287 T intron GWASdb_trait 11 35823818 rs671783 C T rs671783 3.23E-06 Serum metabolites HPOID:0011111 NA G intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000166326.6 TRIM44 612298