PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM44 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G TRIM69 TRIM44 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G G GP G G G GP GP G GP G GP GP GP G APP TRIM44 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G CUL2 TRIM44 21145461 biogrid exp GP GP G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP GP G G G GP GP G TRIM44 TRIM17 19358823 biogrid exp P P P P P P P P P P P P P P P P P GP NEDD4 TRIM44 19953087 biogrid exp GP GP G GP P G GP GP GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP P G TRIM44 HINFP 17577209 biogrid exp G GP G G G GP G P G G GP G GP G G G GP G GP G P G GP GP G GP G GP PBX3 TRIM44 25416956 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP G G G GP G GP G GP GP GP G G GP GP G G CHUK TRIM44 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PPA1 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM44 GOLPH3 21836163 pred GP GP G G GP GP G G GP G GP G G GP G GP GP G GP G GP GP GP G GP G GP GP G HMGN3 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP G GP GP G PRKRIR TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM44 CDK5RAP3 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RPS15 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G TTC19 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM44 UFC1 21836163 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G TRIM44 ACTR10 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NDUFC2 TRIM44 21836163 pred P P P P P P P P P P P P P P P P P P TRIM44 SNF8 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM44 MMADHC 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PITPNB TRIM44 21836163 pred G GP G G GP G G G GP G GP G G G G G G G GP G GP G G G G GP G G G TRIM44 SPG21 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE2Q1 TRIM44 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM44 B3GNT4 21836163 pred GP G G G G GP G GP GP G G G G G GP G G G G G G GP G G G G TRIM44 MRPL18 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM44 PFDN2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ATP5L TRIM44 21836163 pred GP GP G G GP GP G GP G G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PSMG2 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TRIM44 LMBRD1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G WDR82 TRIM44 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATP5E TRIM44 21836163 pred G G G G G G G GP GP G G G G G G GP G G GP G G G G G GP G G G G SF3B1 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM44 FAM21C 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G SP4 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G EDF1 TRIM44 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96DX7 Q13617 affinity chromatography technology 21145461 physical association X 2 Q96DX7 P40426-4 two hybrid 25416956 direct interaction X 2 Q96DX7 P46934-4 enzymatic study 19953087 direct interaction X 2 Q96DX7 Q9Y577-2 two hybrid 19358823 direct interaction X 2 Q96DX7 Q9Y577-2 affinity chromatography technology 19358823 physical association X 2 Q96DX7 Q9Y577-2 affinity chromatography technology 19358823 physical association X 2 P0CG48 Q96DX7 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q96DX7 affinity chromatography technology 18781797 physical association X 2 P0CG48 Q96DX7 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q96DX7 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q96DX7 affinity chromatography technology 21906983 physical association X 2 Q96DX7 A0A024R3F5 two hybrid 17577209 direct interaction X 2 Q96DX7 P05067-7 pull down 21832049 direct interaction X 2 Q96DX7 Q86WT6-3 two hybrid 25416956 direct interaction X 2 Q5JS98 Q96DX7 two hybrid prey pooling approach 25416956 physical association X 2 Q5JS98 Q96DX7 two hybrid array 25416956 physical association X 2 Q5JS98 Q96DX7 validated two hybrid 25416956 physical association X 2 Q96DX7 protein array 23487458 association C 96 Q86WT6 Q96DX7 two hybrid prey pooling approach 25416956 physical association X 2 Q86WT6 Q96DX7 two hybrid array 25416956 physical association X 2 Q86WT6 Q96DX7 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B APP TRIM44 MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_228727 prey bait NEDD4 TRIM44 MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_148258 bait prey CUL2 TRIM44 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_204046 bait prey TRIM44 HINFP MI:0018(two hybrid) 17577209 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_217511 prey bait TRIM44 TRIM17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19358823 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_148450|BIOGRID_148451|BIOGRID_148449 prey|bait|prey bait|prey|bait UBC TRIM44 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18781797,21890473,21906983,21963094,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_181127|BIOGRID_166432|BIOGRID_173007|BIOGRID_162250|BIOGRID_268099 bait|bait|bait|bait|bait prey|prey|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality CUL2 TRIM44 21145461 0004 HT TRIM44 TRIM10 26186194 0004 HT CUL2 TRIM44 21145461 0004 HT TRIM44 TRIM10 26186194 0004 HT PBX3 TRIM44 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT NEDD4 TRIM44 19953087 0415 HT TRIM69 TRIM44 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRIM44 HINFP 17577209 0018 LC TRIM44 TRIM17 19358823,19358823 0004,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96DX7 Q5JS98 TRIM44 PBX3 {ECO:0000313|ENSEMBL:ENSP00000362586} 0.332 25416956 Q96DX7 Q8NDC4 TRIM44 MORN4 0.236 unassigned1304 Q96DX7 Q86WT6 TRIM44 TRIM69 0.454 25416956 Q9NRD5 Q96DX7 PICK1 TRIM44 0.236 unassigned1304 Q96DX7 P05067 TRIM44 APP 0.183 21832049 Q9Y577 Q96DX7 TRIM17 TRIM44 0.569 19358823 Q9BQA5 Q96DX7 HINFP TRIM44 0.309 17577209 Q9UDY6 Q96DX7 TRIM10 TRIM44 0.332 unassigned1304,26186194 Q96DX7 P40426 TRIM44 PBX3 0.183 25416956 Q96DX7 P46934 TRIM44 NEDD4 0.183 19953087 Q96DX7 Q13617 TRIM44 CUL2 0.126 21145461

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MYC TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database APP TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database UBC TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database PBX3 TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4 TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database MAX TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database CUL2 TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database TRIM69 TRIM44 MI:0045 experimental interaction detection MI:0461 interaction database TRIM44 HINFP MI:0045 experimental interaction detection MI:0461 interaction database TRIM44 TRIM10 MI:0045 experimental interaction detection MI:0461 interaction database TRIM44 TRIM17 MI:0045 experimental interaction detection MI:0461 interaction database