Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 15 68582015 68582015 + Missense_Mutation SNP C C G TCGA-DK-A6B6-01A-11D-A30E-08 TCGA-DK-A6B6-10A-01D-A30H-08 g.chr15:68582015C>G c.319C>G c.(319-321)Cta>Gta p.L107V BLCA 15 68582398 68582398 + Silent SNP C C T TCGA-DK-A1A3-01A-11D-A13W-08 TCGA-DK-A1A3-10A-01D-A13W-08 g.chr15:68582398C>T c.702C>T c.(700-702)gtC>gtT p.V234V BLCA 15 68582602 68582602 + Silent SNP T T C TCGA-LT-A5Z6-01A-11D-A289-08 TCGA-LT-A5Z6-10A-01D-A289-08 g.chr15:68582602T>C c.906T>C c.(904-906)taT>taC p.Y302Y BLCA 15 68582890 68582890 + Missense_Mutation SNP G G C TCGA-DK-A6B6-01A-11D-A30E-08 TCGA-DK-A6B6-10A-01D-A30H-08 g.chr15:68582890G>C c.1194G>C c.(1192-1194)ttG>ttC p.L398F BLCA 15 68583478 68583478 + Silent SNP G G A TCGA-XF-AAN0-01A-11D-A42E-08 TCGA-XF-AAN0-10A-01D-A42H-08 g.chr15:68583478G>A c.1782G>A c.(1780-1782)aaG>aaA p.K594K BRCA 15 68582349 68582349 + Missense_Mutation SNP A A T TCGA-BH-A0HB-01A-11W-A071-09 TCGA-BH-A0HB-10A-01W-A071-09 g.chr15:68582349A>T c.653A>T c.(652-654)cAt>cTt p.H218L BRCA 15 68582869 68582869 + Silent SNP T T A TCGA-E2-A15J-01A-11D-A12Q-09 TCGA-E2-A15J-10A-01D-A12Q-09 g.chr15:68582869T>A c.1173T>A c.(1171-1173)gtT>gtA p.V391V CESC 15 68582020 68582020 + Silent SNP C C A TCGA-EK-A3GK-01A-11D-A20U-09 TCGA-EK-A3GK-10A-01D-A20U-09 g.chr15:68582020C>A c.324C>A c.(322-324)gtC>gtA p.V108V CESC 15 68582061 68582061 + Missense_Mutation SNP C C T TCGA-LP-A4AV-01A-11D-A243-09 TCGA-LP-A4AV-10A-01D-A243-09 g.chr15:68582061C>T c.365C>T c.(364-366)tCa>tTa p.S122L CESC 15 68582295 68582295 + Missense_Mutation SNP T T G TCGA-IR-A3LB-01A-11D-A243-09 TCGA-IR-A3LB-10A-01D-A243-09 g.chr15:68582295T>G c.599T>G c.(598-600)aTa>aGa p.I200R CESC 15 68582995 68582995 + Silent SNP C C T TCGA-C5-A7UH-01A-11D-A351-09 TCGA-C5-A7UH-10A-01D-A351-09 g.chr15:68582995C>T c.1299C>T c.(1297-1299)gtC>gtT p.V433V CESC 15 68583077 68583077 + Missense_Mutation SNP G G A TCGA-FU-A3HZ-01A-11D-A20U-09 TCGA-FU-A3HZ-10A-01D-A20U-09 g.chr15:68583077G>A c.1381G>A c.(1381-1383)Gaa>Aaa p.E461K CESC 15 68583140 68583140 + Missense_Mutation SNP C C T TCGA-C5-A1BI-01B-11D-A13W-08 TCGA-C5-A1BI-10A-01D-A13W-08 g.chr15:68583140C>T c.1444C>T c.(1444-1446)Cgt>Tgt p.R482C COAD 15 68582358 68582358 + Missense_Mutation SNP C C T TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr15:68582358C>T c.662C>T c.(661-663)aCg>aTg p.T221M COAD 15 68582375 68582375 + Missense_Mutation SNP G G A TCGA-AA-3712-01A-21D-1719-10 TCGA-AA-3712-11A-01D-1719-10 g.chr15:68582375G>A c.679G>A c.(679-681)Gcc>Acc p.A227T COAD 15 68582432 68582432 + Silent SNP C C A TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr15:68582432C>A c.736C>A c.(736-738)Cga>Aga p.R246R COAD 15 68583135 68583135 + Missense_Mutation SNP G G A TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr15:68583135G>A c.1439G>A c.(1438-1440)aGa>aAa p.R480K COAD 15 68583559 68583559 + Silent SNP A A G TCGA-AY-4070-01A-01W-1073-09 TCGA-AY-4070-10A-01W-1073-09 g.chr15:68583559A>G c.1863A>G c.(1861-1863)gaA>gaG p.E621E COADREAD 15 68582358 68582358 + Missense_Mutation SNP C C T TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr15:68582358C>T c.662C>T c.(661-663)aCg>aTg p.T221M COADREAD 15 68582375 68582375 + Missense_Mutation SNP G G A TCGA-AA-3712-01A-21D-1719-10 TCGA-AA-3712-11A-01D-1719-10 g.chr15:68582375G>A c.679G>A c.(679-681)Gcc>Acc p.A227T COADREAD 15 68582432 68582432 + Silent SNP C C A TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr15:68582432C>A c.736C>A c.(736-738)Cga>Aga p.R246R COADREAD 15 68583063 68583063 + Missense_Mutation SNP A A C TCGA-DY-A1DC-01A-31D-A152-10 TCGA-DY-A1DC-10A-01D-A152-10 g.chr15:68583063A>C c.1367A>C c.(1366-1368)aAa>aCa p.K456T COADREAD 15 68583135 68583135 + Missense_Mutation SNP G G A TCGA-AA-3510-01A-01D-1408-10 TCGA-AA-3510-11A-01D-1408-10 g.chr15:68583135G>A c.1439G>A c.(1438-1440)aGa>aAa p.R480K COADREAD 15 68583559 68583559 + Silent SNP A A G TCGA-AY-4070-01A-01W-1073-09 TCGA-AY-4070-10A-01W-1073-09 g.chr15:68583559A>G c.1863A>G c.(1861-1863)gaA>gaG p.E621E DLBC 15 68583506 68583506 + Missense_Mutation SNP G G A TCGA-FF-A7CQ-01A-11D-A382-10 TCGA-FF-A7CQ-10A-01D-A385-10 g.chr15:68583506G>A c.1810G>A c.(1810-1812)Gca>Aca p.A604T ESCA 15 68582040 68582040 + Missense_Mutation SNP A A G TCGA-IC-A6RE-01A-11D-A33E-09 TCGA-IC-A6RE-10A-01D-A33H-09 g.chr15:68582040A>G c.344A>G c.(343-345)aAc>aGc p.N115S ESCA 15 68582270 68582270 + Missense_Mutation SNP C C T TCGA-V5-AASV-01A-11D-A387-09 TCGA-V5-AASV-10A-01D-A38A-09 g.chr15:68582270C>T c.574C>T c.(574-576)Cac>Tac p.H192Y GBMLGG 15 68583125 68583125 + Missense_Mutation SNP C C A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr15:68583125C>A c.1429C>A c.(1429-1431)Ctt>Att p.L477I HNSC 15 68582025 68582025 + Missense_Mutation SNP A A G TCGA-CQ-5330-01A-01D-1683-08 TCGA-CQ-5330-10A-01D-1683-08 g.chr15:68582025A>G c.329A>G c.(328-330)cAt>cGt p.H110R HNSC 15 68582120 68582120 + Missense_Mutation SNP G G A TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr15:68582120G>A c.424G>A c.(424-426)Gaa>Aaa p.E142K HNSC 15 68582393 68582393 + Missense_Mutation SNP G G A TCGA-BB-A6UM-01A-12D-A34J-08 TCGA-BB-A6UM-10A-01D-A34M-08 g.chr15:68582393G>A c.697G>A c.(697-699)Gat>Aat p.D233N HNSC 15 68583057 68583057 + Missense_Mutation SNP C C G TCGA-CQ-7071-01A-12D-A30E-08 TCGA-CQ-7071-10A-01D-A30H-08 g.chr15:68583057C>G c.1361C>G c.(1360-1362)tCt>tGt p.S454C KIPAN 15 68582267 68582267 + Silent SNP T T C TCGA-BP-4162-01A-02D-1386-10 TCGA-BP-4162-11A-01D-1251-10 g.chr15:68582267T>C c.571T>C c.(571-573)Ttg>Ctg p.L191L KIPAN 15 68582628 68582628 + Missense_Mutation SNP C C A TCGA-B8-5162-01A-01D-1421-08 TCGA-B8-5162-10A-01D-1421-08 g.chr15:68582628C>A c.932C>A c.(931-933)cCt>cAt p.P311H KIPAN 15 68582835 68582835 + Missense_Mutation SNP A A T TCGA-B0-5709-01A-11D-1534-10 TCGA-B0-5709-11A-01D-1534-10 g.chr15:68582835A>T c.1139A>T c.(1138-1140)aAc>aTc p.N380I KIRC 15 68582267 68582267 + Silent SNP T T C TCGA-BP-4162-01A-02D-1386-10 TCGA-BP-4162-11A-01D-1251-10 g.chr15:68582267T>C c.571T>C c.(571-573)Ttg>Ctg p.L191L KIRC 15 68582628 68582628 + Missense_Mutation SNP C C A TCGA-B8-5162-01A-01D-1421-08 TCGA-B8-5162-10A-01D-1421-08 g.chr15:68582628C>A c.932C>A c.(931-933)cCt>cAt p.P311H KIRC 15 68582835 68582835 + Missense_Mutation SNP A A T TCGA-B0-5709-01A-11D-1534-10 TCGA-B0-5709-11A-01D-1534-10 g.chr15:68582835A>T c.1139A>T c.(1138-1140)aAc>aTc p.N380I LGG 15 68583125 68583125 + Missense_Mutation SNP C C A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr15:68583125C>A c.1429C>A c.(1429-1431)Ctt>Att p.L477I LIHC 15 68582064 68582064 + Frame_Shift_Del DEL C C - TCGA-G3-A3CJ-01A-11D-A20W-10 TCGA-G3-A3CJ-10A-01D-A20W-10 g.chr15:68582064delC c.368delC c.(367-369)accfs p.T123fs LUAD 15 68570886 68570886 + Missense_Mutation SNP G G T TCGA-17-Z028-01A-01W-0746-08 TCGA-17-Z028-11A-01W-0746-08 g.chr15:68570886G>T c.131G>T c.(130-132)gGg>gTg p.G44V LUAD 15 68582098 68582098 + Silent SNP G G C TCGA-86-8279-01A-11D-2284-08 TCGA-86-8279-10A-01D-2284-08 g.chr15:68582098G>C c.402G>C c.(400-402)ctG>ctC p.L134L LUAD 15 68582377 68582377 + Silent SNP C C A TCGA-55-6985-01A-11D-1945-08 TCGA-55-6985-11A-01D-1945-08 g.chr15:68582377C>A c.681C>A c.(679-681)gcC>gcA p.A227A LUAD 15 68582664 68582665 + In_Frame_Ins INS - - TCA TCGA-55-8614-01A-11D-2393-08 TCGA-55-8614-10A-01D-2393-08 g.chr15:68582664_68582665insTCA c.968_969insTCA c.(967-972)gctctt>gcTCAtctt p.323_324AL>AHL LUAD 15 68583191 68583191 + Missense_Mutation SNP G G A TCGA-99-8032-01A-11D-2238-08 TCGA-99-8032-10A-01D-2238-08 g.chr15:68583191G>A c.1495G>A c.(1495-1497)Gat>Aat p.D499N LUAD 15 68583378 68583378 + Missense_Mutation SNP A A C TCGA-35-4122-01A-01D-1105-08 TCGA-35-4122-10A-01D-1105-08 g.chr15:68583378A>C c.1682A>C c.(1681-1683)gAa>gCa p.E561A LUSC 15 68570955 68570955 + Missense_Mutation SNP A A G TCGA-43-5668-01A-01D-1632-08 TCGA-43-5668-11A-01D-1632-08 g.chr15:68570955A>G c.200A>G c.(199-201)gAa>gGa p.E67G LUSC 15 68582855 68582855 + Nonsense_Mutation SNP C C T TCGA-18-3406-01A-01D-0983-08 TCGA-18-3406-11A-01D-0983-08 g.chr15:68582855C>T c.1159C>T c.(1159-1161)Cga>Tga p.R387* LUSC 15 68582929 68582929 + Missense_Mutation SNP G G C TCGA-22-5473-01A-01D-1632-08 TCGA-22-5473-11A-11D-1632-08 g.chr15:68582929G>C c.1233G>C c.(1231-1233)ttG>ttC p.L411F PAAD 15 68570843 68570843 + Missense_Mutation SNP A A G TCGA-FB-AAPZ-01A-11D-A40W-08 TCGA-FB-AAPZ-11A-11D-A40W-08 g.chr15:68570843A>G c.88A>G c.(88-90)Agc>Ggc p.S30G PAAD 15 68582429 68582429 + Missense_Mutation SNP G G T TCGA-YB-A89D-01A-12D-A36O-08 TCGA-YB-A89D-10A-01D-A367-08 g.chr15:68582429G>T c.733G>T c.(733-735)Gac>Tac p.D245Y PAAD 15 68583276 68583276 + Missense_Mutation SNP C C T TCGA-2J-AAB6-01A-11D-A40W-08 TCGA-2J-AAB6-10A-01D-A40W-08 g.chr15:68583276C>T c.1580C>T c.(1579-1581)gCc>gTc p.A527V PCPG 15 68581943 68581943 + Splice_Site SNP A A G TCGA-QR-A6H5-01A-11D-A35D-08 TCGA-QR-A6H5-10A-01D-A35B-08 g.chr15:68581943A>G c.e2-1 PRAD 15 68583314 68583314 + Missense_Mutation SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr15:68583314G>A c.1618G>A c.(1618-1620)Gtt>Att p.V540I READ 15 68583063 68583063 + Missense_Mutation SNP A A C TCGA-DY-A1DC-01A-31D-A152-10 TCGA-DY-A1DC-10A-01D-A152-10 g.chr15:68583063A>C c.1367A>C c.(1366-1368)aAa>aCa p.K456T SKCM 15 68582855 68582855 + Nonsense_Mutation SNP C C T TCGA-DA-A1HV-06A-21D-A196-08 TCGA-DA-A1HV-10A-01D-A198-08 g.chr15:68582855C>T c.1159C>T c.(1159-1161)Cga>Tga p.R387* SKCM 15 68582855 68582855 + Nonsense_Mutation SNP C C T TCGA-EE-A3AA-06A-11D-A196-08 TCGA-EE-A3AA-10A-01D-A198-08 g.chr15:68582855C>T c.1159C>T c.(1159-1161)Cga>Tga p.R387* SKCM 15 68583223 68583223 + Silent SNP T T C TCGA-EE-A3AB-06A-11D-A196-08 TCGA-EE-A3AB-10A-01D-A198-08 g.chr15:68583223T>C c.1527T>C c.(1525-1527)ttT>ttC p.F509F

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 15 68582398 68582398 single base substitution C T downstream_gene_variant BLCA-US 15 68582398 68582398 single base substitution C T synonymous_variant V234V 702C>T BLCA-US 15 68582398 68582398 single base substitution C T synonymous_variant V76V 228C>T BLCA-US 15 68582398 68582398 single base substitution C T upstream_gene_variant BRCA-EU 15 68568607 68568607 single base substitution C T upstream_gene_variant BRCA-EU 15 68569637 68569637 single base substitution C T upstream_gene_variant BRCA-EU 15 68570385 68570385 single base substitution G A 5_prime_UTR_variant BRCA-EU 15 68570385 68570385 single base substitution G A upstream_gene_variant BRCA-EU 15 68570795 68570795 single base substitution G A missense_variant E14K 40G>A BRCA-EU 15 68570795 68570795 single base substitution G A upstream_gene_variant BRCA-EU 15 68571248 68571248 single base substitution C T intron_variant BRCA-EU 15 68571248 68571248 single base substitution C T upstream_gene_variant BRCA-EU 15 68572371 68572371 single base substitution T C 5_prime_UTR_variant BRCA-EU 15 68572371 68572371 single base substitution T C intron_variant BRCA-EU 15 68572501 68572501 single base substitution T A 5_prime_UTR_variant BRCA-EU 15 68572501 68572501 single base substitution T A intron_variant BRCA-EU 15 68572699 68572699 single base substitution A G intron_variant BRCA-EU 15 68574150 68574150 single base substitution C A intron_variant BRCA-EU 15 68574521 68574521 single base substitution A T intron_variant BRCA-EU 15 68575785 68575785 single base substitution T C intron_variant BRCA-EU 15 68577881 68577881 single base substitution C G intron_variant BRCA-EU 15 68577881 68577881 single base substitution C G upstream_gene_variant BRCA-EU 15 68578144 68578144 single base substitution T C intron_variant BRCA-EU 15 68578144 68578144 single base substitution T C upstream_gene_variant BRCA-EU 15 68578931 68578931 single base substitution C G intron_variant BRCA-EU 15 68578931 68578931 single base substitution C G upstream_gene_variant BRCA-EU 15 68578950 68578950 single base substitution T G intron_variant BRCA-EU 15 68578950 68578950 single base substitution T G upstream_gene_variant BRCA-EU 15 68581170 68581170 single base substitution A G intron_variant BRCA-EU 15 68581170 68581170 single base substitution A G upstream_gene_variant BRCA-EU 15 68582515 68582515 single base substitution C A downstream_gene_variant BRCA-EU 15 68582515 68582515 single base substitution C A stop_gained Y273* 819C>A BRCA-EU 15 68582515 68582515 single base substitution C A upstream_gene_variant BRCA-EU 15 68582833 68582833 single base substitution G C downstream_gene_variant BRCA-EU 15 68582833 68582833 single base substitution G C intron_variant BRCA-EU 15 68582833 68582833 single base substitution G C missense_variant R379S 1137G>C BRCA-EU 15 68584344 68584344 single base substitution T A 3_prime_UTR_variant BRCA-EU 15 68584344 68584344 single base substitution T A downstream_gene_variant BRCA-EU 15 68585036 68585036 deletion of <=200bp A - 3_prime_UTR_variant BRCA-EU 15 68585036 68585036 deletion of <=200bp A - downstream_gene_variant BRCA-EU 15 68585111 68585111 single base substitution T A 3_prime_UTR_variant BRCA-EU 15 68585111 68585111 single base substitution T A downstream_gene_variant BRCA-EU 15 68586150 68586150 single base substitution T A 3_prime_UTR_variant BRCA-EU 15 68586150 68586150 single base substitution T A downstream_gene_variant BRCA-EU 15 68587205 68587205 single base substitution T G 3_prime_UTR_variant BRCA-EU 15 68587205 68587205 single base substitution T G downstream_gene_variant BRCA-EU 15 68587647 68587647 single base substitution A C 3_prime_UTR_variant BRCA-EU 15 68587647 68587647 single base substitution A C downstream_gene_variant BRCA-EU 15 68589290 68589290 insertion of <=200bp - T downstream_gene_variant BRCA-EU 15 68590262 68590262 single base substitution G C downstream_gene_variant BRCA-EU 15 68592474 68592474 single base substitution A C downstream_gene_variant BRCA-FR 15 68568607 68568607 single base substitution C T upstream_gene_variant BRCA-FR 15 68571248 68571248 single base substitution C T intron_variant BRCA-FR 15 68571248 68571248 single base substitution C T upstream_gene_variant BRCA-FR 15 68578144 68578144 single base substitution T C intron_variant BRCA-FR 15 68578144 68578144 single base substitution T C upstream_gene_variant BRCA-FR 15 68582515 68582515 single base substitution C A downstream_gene_variant BRCA-FR 15 68582515 68582515 single base substitution C A stop_gained Y273* 819C>A BRCA-FR 15 68582515 68582515 single base substitution C A upstream_gene_variant BRCA-UK 15 68569276 68569276 single base substitution G C upstream_gene_variant BRCA-US 15 68582349 68582349 single base substitution A T downstream_gene_variant BRCA-US 15 68582349 68582349 single base substitution A T missense_variant H218L 653A>T BRCA-US 15 68582349 68582349 single base substitution A T missense_variant H60L 179A>T BRCA-US 15 68582349 68582349 single base substitution A T upstream_gene_variant BRCA-US 15 68582869 68582869 single base substitution T A downstream_gene_variant BRCA-US 15 68582869 68582869 single base substitution T A intron_variant BRCA-US 15 68582869 68582869 single base substitution T A synonymous_variant V391V 1173T>A BTCA-JP 15 68581901 68581901 single base substitution G A intron_variant BTCA-JP 15 68581901 68581901 single base substitution G A upstream_gene_variant BTCA-JP 15 68583122 68583122 single base substitution C T downstream_gene_variant BTCA-JP 15 68583122 68583122 single base substitution C T missense_variant H117Y 349C>T BTCA-JP 15 68583122 68583122 single base substitution C T missense_variant H476Y 1426C>T CESC-US 15 68582020 68582020 single base substitution C A 5_prime_UTR_variant CESC-US 15 68582020 68582020 single base substitution C A synonymous_variant V108V 324C>A CESC-US 15 68582020 68582020 single base substitution C A upstream_gene_variant CESC-US 15 68582061 68582061 single base substitution C T 5_prime_UTR_variant CESC-US 15 68582061 68582061 single base substitution C T missense_variant S122L 365C>T CESC-US 15 68582061 68582061 single base substitution C T upstream_gene_variant CESC-US 15 68582295 68582295 single base substitution T G downstream_gene_variant CESC-US 15 68582295 68582295 single base substitution T G missense_variant I200R 599T>G CESC-US 15 68582295 68582295 single base substitution T G missense_variant I42R 125T>G CESC-US 15 68582295 68582295 single base substitution T G upstream_gene_variant CESC-US 15 68582995 68582995 single base substitution C T downstream_gene_variant CESC-US 15 68582995 68582995 single base substitution C T intron_variant CESC-US 15 68582995 68582995 single base substitution C T synonymous_variant V433V 1299C>T CESC-US 15 68583077 68583077 single base substitution G A downstream_gene_variant CESC-US 15 68583077 68583077 single base substitution G A missense_variant E102K 304G>A CESC-US 15 68583077 68583077 single base substitution G A missense_variant E461K 1381G>A CESC-US 15 68583140 68583140 single base substitution C T downstream_gene_variant CESC-US 15 68583140 68583140 single base substitution C T missense_variant R123C 367C>T CESC-US 15 68583140 68583140 single base substitution C T missense_variant R482C 1444C>T COAD-US 15 68582358 68582358 single base substitution C T downstream_gene_variant COAD-US 15 68582358 68582358 single base substitution C T missense_variant T221M 662C>T COAD-US 15 68582358 68582358 single base substitution C T missense_variant T63M 188C>T COAD-US 15 68582358 68582358 single base substitution C T upstream_gene_variant COAD-US 15 68582375 68582375 single base substitution G A downstream_gene_variant COAD-US 15 68582375 68582375 single base substitution G A missense_variant A227T 679G>A COAD-US 15 68582375 68582375 single base substitution G A missense_variant A69T 205G>A COAD-US 15 68582375 68582375 single base substitution G A upstream_gene_variant COAD-US 15 68582432 68582432 single base substitution C A downstream_gene_variant COAD-US 15 68582432 68582432 single base substitution C A synonymous_variant R246R 736C>A COAD-US 15 68582432 68582432 single base substitution C A upstream_gene_variant COAD-US 15 68583135 68583135 single base substitution G A downstream_gene_variant COAD-US 15 68583135 68583135 single base substitution G A missense_variant R121K 362G>A COAD-US 15 68583135 68583135 single base substitution G A missense_variant R480K 1439G>A COCA-CN 15 68570992 68570992 single base substitution C A synonymous_variant V79V 237C>A COCA-CN 15 68570992 68570992 single base substitution C A upstream_gene_variant COCA-CN 15 68583094 68583094 single base substitution A C downstream_gene_variant COCA-CN 15 68583094 68583094 single base substitution A C missense_variant K107N 321A>C COCA-CN 15 68583094 68583094 single base substitution A C missense_variant K466N 1398A>C ESAD-UK 15 68566347 68566347 single base substitution T C upstream_gene_variant ESAD-UK 15 68566421 68566421 single base substitution T C upstream_gene_variant ESAD-UK 15 68570016 68570016 single base substitution G T upstream_gene_variant ESAD-UK 15 68570376 68570376 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant ESAD-UK 15 68570376 68570376 single base substitution C T upstream_gene_variant ESAD-UK 15 68578847 68578847 single base substitution A G intron_variant ESAD-UK 15 68578847 68578847 single base substitution A G upstream_gene_variant ESAD-UK 15 68579005 68579005 single base substitution G T intron_variant ESAD-UK 15 68579005 68579005 single base substitution G T upstream_gene_variant ESAD-UK 15 68579139 68579139 insertion of <=200bp - A intron_variant ESAD-UK 15 68579139 68579139 insertion of <=200bp - A upstream_gene_variant ESAD-UK 15 68579684 68579684 single base substitution T C intron_variant ESAD-UK 15 68579684 68579684 single base substitution T C upstream_gene_variant ESAD-UK 15 68579994 68579994 single base substitution G T intron_variant ESAD-UK 15 68579994 68579994 single base substitution G T upstream_gene_variant ESAD-UK 15 68581203 68581203 single base substitution C T intron_variant ESAD-UK 15 68581203 68581203 single base substitution C T upstream_gene_variant ESAD-UK 15 68581270 68581270 single base substitution A C intron_variant ESAD-UK 15 68581270 68581270 single base substitution A C upstream_gene_variant ESAD-UK 15 68586667 68586667 single base substitution C G 3_prime_UTR_variant ESAD-UK 15 68586667 68586667 single base substitution C G downstream_gene_variant ESAD-UK 15 68587598 68587598 single base substitution C G 3_prime_UTR_variant ESAD-UK 15 68587598 68587598 single base substitution C G downstream_gene_variant ESAD-UK 15 68587803 68587803 single base substitution C G 3_prime_UTR_variant ESAD-UK 15 68587803 68587803 single base substitution C G downstream_gene_variant ESAD-UK 15 68587855 68587855 single base substitution A G 3_prime_UTR_variant ESAD-UK 15 68587855 68587855 single base substitution A G downstream_gene_variant ESAD-UK 15 68588124 68588124 single base substitution C T 3_prime_UTR_variant ESAD-UK 15 68588124 68588124 single base substitution C T downstream_gene_variant ESAD-UK 15 68588385 68588385 single base substitution C T downstream_gene_variant ESAD-UK 15 68589083 68589083 single base substitution C A downstream_gene_variant ESCA-CN 15 68582569 68582569 single base substitution C T downstream_gene_variant ESCA-CN 15 68582569 68582569 single base substitution C T synonymous_variant L291L 873C>T ESCA-CN 15 68582569 68582569 single base substitution C T synonymous_variant L6L 18C>T KIRC-US 15 68582267 68582267 single base substitution T C downstream_gene_variant KIRC-US 15 68582267 68582267 single base substitution T C synonymous_variant L191L 571T>C KIRC-US 15 68582267 68582267 single base substitution T C synonymous_variant L33L 97T>C KIRC-US 15 68582267 68582267 single base substitution T C upstream_gene_variant KIRC-US 15 68582835 68582835 single base substitution A T downstream_gene_variant KIRC-US 15 68582835 68582835 single base substitution A T intron_variant KIRC-US 15 68582835 68582835 single base substitution A T missense_variant N380I 1139A>T LICA-CN 15 68582155 68582155 single base substitution T C 5_prime_UTR_variant LICA-CN 15 68582155 68582155 single base substitution T C synonymous_variant Y153Y 459T>C LICA-CN 15 68582155 68582155 single base substitution T C upstream_gene_variant LICA-CN 15 68582597 68582597 single base substitution G T downstream_gene_variant LICA-CN 15 68582597 68582597 single base substitution G T missense_variant A16S 46G>T LICA-CN 15 68582597 68582597 single base substitution G T missense_variant A301S 901G>T LICA-FR 15 68570798 68570798 single base substitution G A missense_variant G15S 43G>A LICA-FR 15 68570798 68570798 single base substitution G A upstream_gene_variant LICA-FR 15 68576146 68576146 single base substitution G A intron_variant LICA-FR 15 68591067 68591067 single base substitution A T downstream_gene_variant LINC-JP 15 68571175 68571175 single base substitution C T intron_variant LINC-JP 15 68571175 68571175 single base substitution C T upstream_gene_variant LINC-JP 15 68574456 68574456 single base substitution A G intron_variant LINC-JP 15 68582228 68582228 single base substitution G T downstream_gene_variant LINC-JP 15 68582228 68582228 single base substitution G T missense_variant A178S 532G>T LINC-JP 15 68582228 68582228 single base substitution G T missense_variant A20S 58G>T LINC-JP 15 68582228 68582228 single base substitution G T upstream_gene_variant LINC-JP 15 68587163 68587163 single base substitution G T 3_prime_UTR_variant LINC-JP 15 68587163 68587163 single base substitution G T downstream_gene_variant LINC-JP 15 68591674 68591674 single base substitution A G downstream_gene_variant LIRI-JP 15 68566922 68566922 single base substitution A C upstream_gene_variant LIRI-JP 15 68567609 68567609 single base substitution G A upstream_gene_variant LIRI-JP 15 68568236 68568236 single base substitution T G upstream_gene_variant LIRI-JP 15 68573854 68573854 single base substitution A G intron_variant LIRI-JP 15 68574636 68574636 single base substitution A C intron_variant LIRI-JP 15 68576553 68576553 single base substitution A G intron_variant LIRI-JP 15 68576693 68576693 single base substitution A G intron_variant LIRI-JP 15 68576693 68576693 single base substitution A G upstream_gene_variant LIRI-JP 15 68577452 68577452 single base substitution A G intron_variant LIRI-JP 15 68577452 68577452 single base substitution A G upstream_gene_variant LIRI-JP 15 68577743 68577743 single base substitution A T intron_variant LIRI-JP 15 68577743 68577743 single base substitution A T upstream_gene_variant LIRI-JP 15 68578655 68578655 single base substitution A T intron_variant LIRI-JP 15 68578655 68578655 single base substitution A T upstream_gene_variant LIRI-JP 15 68579538 68579538 single base substitution C T intron_variant LIRI-JP 15 68579538 68579538 single base substitution C T upstream_gene_variant LIRI-JP 15 68579845 68579845 single base substitution G A intron_variant LIRI-JP 15 68579845 68579845 single base substitution G A upstream_gene_variant LIRI-JP 15 68580217 68580217 single base substitution G T intron_variant LIRI-JP 15 68580217 68580217 single base substitution G T upstream_gene_variant LIRI-JP 15 68583882 68583882 single base substitution T C 3_prime_UTR_variant LIRI-JP 15 68583882 68583882 single base substitution T C downstream_gene_variant LIRI-JP 15 68584259 68584259 insertion of <=200bp - TGA 3_prime_UTR_variant LIRI-JP 15 68584259 68584259 insertion of <=200bp - TGA downstream_gene_variant LIRI-JP 15 68585076 68585076 single base substitution G A 3_prime_UTR_variant LIRI-JP 15 68585076 68585076 single base substitution G A downstream_gene_variant LIRI-JP 15 68585233 68585233 single base substitution G T 3_prime_UTR_variant LIRI-JP 15 68585233 68585233 single base substitution G T downstream_gene_variant LIRI-JP 15 68585774 68585774 single base substitution A G 3_prime_UTR_variant LIRI-JP 15 68585774 68585774 single base substitution A G downstream_gene_variant LIRI-JP 15 68585913 68585913 single base substitution A G 3_prime_UTR_variant LIRI-JP 15 68585913 68585913 single base substitution A G downstream_gene_variant LIRI-JP 15 68587470 68587470 single base substitution T C 3_prime_UTR_variant LIRI-JP 15 68587470 68587470 single base substitution T C downstream_gene_variant LIRI-JP 15 68587814 68587814 single base substitution A G 3_prime_UTR_variant LIRI-JP 15 68587814 68587814 single base substitution A G downstream_gene_variant LIRI-JP 15 68588037 68588037 single base substitution T G 3_prime_UTR_variant LIRI-JP 15 68588037 68588037 single base substitution T G downstream_gene_variant LIRI-JP 15 68589697 68589697 single base substitution A G downstream_gene_variant LIRI-JP 15 68591515 68591515 insertion of <=200bp - A downstream_gene_variant LUSC-KR 15 68565540 68565540 single base substitution G A upstream_gene_variant LUSC-KR 15 68566574 68566574 single base substitution C G upstream_gene_variant LUSC-KR 15 68567982 68567982 single base substitution C G upstream_gene_variant LUSC-KR 15 68568602 68568602 single base substitution T C upstream_gene_variant LUSC-KR 15 68571416 68571416 single base substitution G A intron_variant LUSC-KR 15 68571416 68571416 single base substitution G A upstream_gene_variant LUSC-KR 15 68572133 68572133 single base substitution A T intron_variant LUSC-KR 15 68572133 68572133 single base substitution A T upstream_gene_variant LUSC-KR 15 68575841 68575841 single base substitution A T intron_variant LUSC-KR 15 68577099 68577099 single base substitution C T intron_variant LUSC-KR 15 68577099 68577099 single base substitution C T upstream_gene_variant LUSC-KR 15 68589407 68589407 single base substitution A C downstream_gene_variant LUSC-KR 15 68591026 68591026 single base substitution C G downstream_gene_variant LUSC-KR 15 68591944 68591944 single base substitution G A downstream_gene_variant LUSC-KR 15 68591953 68591953 single base substitution G C downstream_gene_variant LUSC-US 15 68570955 68570955 single base substitution A G missense_variant E67G 200A>G LUSC-US 15 68570955 68570955 single base substitution A G upstream_gene_variant LUSC-US 15 68582855 68582855 single base substitution C T downstream_gene_variant LUSC-US 15 68582855 68582855 single base substitution C T intron_variant LUSC-US 15 68582855 68582855 single base substitution C T stop_gained R387* 1159C>T LUSC-US 15 68582929 68582929 single base substitution G C downstream_gene_variant LUSC-US 15 68582929 68582929 single base substitution G C intron_variant LUSC-US 15 68582929 68582929 single base substitution G C missense_variant L411F 1233G>C MALY-DE 15 68582727 68582727 single base substitution C G downstream_gene_variant MALY-DE 15 68582727 68582727 single base substitution C G missense_variant S344C 1031C>G MALY-DE 15 68582727 68582727 single base substitution C G missense_variant S59C 176C>G MALY-DE 15 68584366 68584366 single base substitution T A 3_prime_UTR_variant MALY-DE 15 68584366 68584366 single base substitution T A downstream_gene_variant MALY-DE 15 68588087 68588087 single base substitution A C 3_prime_UTR_variant MALY-DE 15 68588087 68588087 single base substitution A C downstream_gene_variant MELA-AU 15 68566824 68566824 single base substitution C T upstream_gene_variant MELA-AU 15 68566843 68566843 single base substitution C T upstream_gene_variant MELA-AU 15 68566855 68566855 single base substitution C T upstream_gene_variant MELA-AU 15 68567655 68567655 single base substitution G A upstream_gene_variant MELA-AU 15 68567657 68567657 single base substitution C G upstream_gene_variant MELA-AU 15 68567780 68567780 single base substitution T A upstream_gene_variant MELA-AU 15 68568057 68568057 single base substitution G A upstream_gene_variant MELA-AU 15 68568663 68568663 single base substitution G A upstream_gene_variant MELA-AU 15 68568830 68568831 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 15 68570087 68570087 single base substitution C G upstream_gene_variant MELA-AU 15 68570670 68570670 single base substitution T C 5_prime_UTR_variant MELA-AU 15 68570670 68570670 single base substitution T C upstream_gene_variant MELA-AU 15 68571409 68571409 single base substitution G C intron_variant MELA-AU 15 68571409 68571409 single base substitution G C upstream_gene_variant MELA-AU 15 68571629 68571629 single base substitution G A intron_variant MELA-AU 15 68571629 68571629 single base substitution G A upstream_gene_variant MELA-AU 15 68571921 68571921 single base substitution T A intron_variant MELA-AU 15 68571921 68571921 single base substitution T A upstream_gene_variant MELA-AU 15 68571943 68571943 single base substitution T A intron_variant MELA-AU 15 68571943 68571943 single base substitution T A upstream_gene_variant MELA-AU 15 68572093 68572093 single base substitution C T intron_variant MELA-AU 15 68572093 68572093 single base substitution C T upstream_gene_variant MELA-AU 15 68574603 68574603 single base substitution C G intron_variant MELA-AU 15 68576817 68576817 single base substitution C T intron_variant MELA-AU 15 68576817 68576817 single base substitution C T upstream_gene_variant MELA-AU 15 68579510 68579510 single base substitution T A intron_variant MELA-AU 15 68579510 68579510 single base substitution T A upstream_gene_variant MELA-AU 15 68581233 68581233 single base substitution C T intron_variant MELA-AU 15 68581233 68581233 single base substitution C T upstream_gene_variant MELA-AU 15 68581370 68581370 single base substitution G A intron_variant MELA-AU 15 68581370 68581370 single base substitution G A upstream_gene_variant MELA-AU 15 68581883 68581883 single base substitution C T intron_variant MELA-AU 15 68581883 68581883 single base substitution C T upstream_gene_variant MELA-AU 15 68582125 68582125 single base substitution T C 5_prime_UTR_variant MELA-AU 15 68582125 68582125 single base substitution T C synonymous_variant N143N 429T>C MELA-AU 15 68582125 68582125 single base substitution T C upstream_gene_variant MELA-AU 15 68582855 68582855 single base substitution C T downstream_gene_variant MELA-AU 15 68582855 68582855 single base substitution C T intron_variant MELA-AU 15 68582855 68582855 single base substitution C T stop_gained R387* 1159C>T MELA-AU 15 68583881 68583881 single base substitution T G 3_prime_UTR_variant MELA-AU 15 68583881 68583881 single base substitution T G downstream_gene_variant MELA-AU 15 68584343 68584343 single base substitution C T 3_prime_UTR_variant MELA-AU 15 68584343 68584343 single base substitution C T downstream_gene_variant MELA-AU 15 68584514 68584514 single base substitution T C 3_prime_UTR_variant MELA-AU 15 68584514 68584514 single base substitution T C downstream_gene_variant MELA-AU 15 68585450 68585450 single base substitution G A 3_prime_UTR_variant MELA-AU 15 68585450 68585450 single base substitution G A downstream_gene_variant MELA-AU 15 68586637 68586638 multiple base substitution (>=2bp and <=200bp) CC TT 3_prime_UTR_variant MELA-AU 15 68586637 68586638 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 15 68587247 68587247 single base substitution G A 3_prime_UTR_variant MELA-AU 15 68587247 68587247 single base substitution G A downstream_gene_variant MELA-AU 15 68587464 68587464 single base substitution A G 3_prime_UTR_variant MELA-AU 15 68587464 68587464 single base substitution A G downstream_gene_variant MELA-AU 15 68587789 68587789 single base substitution C T 3_prime_UTR_variant MELA-AU 15 68587789 68587789 single base substitution C T downstream_gene_variant MELA-AU 15 68589513 68589513 single base substitution C T downstream_gene_variant MELA-AU 15 68590283 68590283 single base substitution A C downstream_gene_variant MELA-AU 15 68590721 68590721 deletion of <=200bp C - downstream_gene_variant MELA-AU 15 68590787 68590787 single base substitution C T downstream_gene_variant MELA-AU 15 68590806 68590806 single base substitution A G downstream_gene_variant MELA-AU 15 68591056 68591056 single base substitution C T downstream_gene_variant MELA-AU 15 68591415 68591415 single base substitution C T downstream_gene_variant MELA-AU 15 68592512 68592512 single base substitution C T downstream_gene_variant OV-AU 15 68566850 68566850 single base substitution A G upstream_gene_variant OV-AU 15 68580348 68580348 single base substitution G T intron_variant OV-AU 15 68580348 68580348 single base substitution G T upstream_gene_variant OV-AU 15 68586169 68586169 single base substitution A T 3_prime_UTR_variant OV-AU 15 68586169 68586169 single base substitution A T downstream_gene_variant PACA-AU 15 68567277 68567277 single base substitution G A upstream_gene_variant PACA-AU 15 68570896 68570896 single base substitution C G synonymous_variant S47S 141C>G PACA-AU 15 68570896 68570896 single base substitution C G upstream_gene_variant PACA-AU 15 68577607 68577607 single base substitution A C intron_variant PACA-AU 15 68577607 68577607 single base substitution A C upstream_gene_variant PACA-AU 15 68582815 68582815 single base substitution C T downstream_gene_variant PACA-AU 15 68582815 68582815 single base substitution C T synonymous_variant L373L 1119C>T PACA-AU 15 68582815 68582815 single base substitution C T synonymous_variant L88L 264C>T PACA-CA 15 68568673 68568673 single base substitution A G upstream_gene_variant PACA-CA 15 68568950 68568950 single base substitution A G upstream_gene_variant PACA-CA 15 68570349 68570349 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant PACA-CA 15 68570349 68570349 single base substitution C T upstream_gene_variant PACA-CA 15 68572351 68572351 single base substitution G A 5_prime_UTR_variant PACA-CA 15 68572351 68572351 single base substitution G A intron_variant PACA-CA 15 68579692 68579692 single base substitution T C intron_variant PACA-CA 15 68579692 68579692 single base substitution T C upstream_gene_variant PACA-CA 15 68582709 68582709 single base substitution C T downstream_gene_variant PACA-CA 15 68582709 68582709 single base substitution C T missense_variant A338V 1013C>T PACA-CA 15 68582709 68582709 single base substitution C T missense_variant A53V 158C>T PACA-CA 15 68585958 68585958 single base substitution G A 3_prime_UTR_variant PACA-CA 15 68585958 68585958 single base substitution G A downstream_gene_variant PACA-CA 15 68589960 68589960 insertion of <=200bp - T downstream_gene_variant PAEN-AU 15 68572503 68572503 insertion of <=200bp - T 5_prime_UTR_variant PAEN-AU 15 68572503 68572503 insertion of <=200bp - T intron_variant PAEN-AU 15 68589234 68589234 single base substitution C A downstream_gene_variant PAEN-IT 15 68577188 68577188 single base substitution G T intron_variant PAEN-IT 15 68577188 68577188 single base substitution G T upstream_gene_variant PBCA-DE 15 68573368 68573368 single base substitution C T intron_variant PBCA-DE 15 68578813 68578814 deletion of <=200bp CA - intron_variant PBCA-DE 15 68578813 68578814 deletion of <=200bp CA - upstream_gene_variant PBCA-DE 15 68583074 68583074 single base substitution A G downstream_gene_variant PBCA-DE 15 68583074 68583074 single base substitution A G missense_variant S101G 301A>G PBCA-DE 15 68583074 68583074 single base substitution A G missense_variant S460G 1378A>G PBCA-DE 15 68586150 68586150 single base substitution T A 3_prime_UTR_variant PBCA-DE 15 68586150 68586150 single base substitution T A downstream_gene_variant PBCA-DE 15 68586597 68586597 single base substitution C T 3_prime_UTR_variant PBCA-DE 15 68586597 68586597 single base substitution C T downstream_gene_variant PRAD-CA 15 68577158 68577158 single base substitution G A intron_variant PRAD-CA 15 68577158 68577158 single base substitution G A upstream_gene_variant PRAD-CA 15 68579226 68579226 single base substitution G C intron_variant PRAD-CA 15 68579226 68579226 single base substitution G C upstream_gene_variant PRAD-UK 15 68581277 68581277 single base substitution A G intron_variant PRAD-UK 15 68581277 68581277 single base substitution A G upstream_gene_variant READ-US 15 68582610 68582610 single base substitution G T downstream_gene_variant READ-US 15 68582610 68582610 single base substitution G T missense_variant R20I 59G>T READ-US 15 68582610 68582610 single base substitution G T missense_variant R305I 914G>T READ-US 15 68583063 68583063 single base substitution A C downstream_gene_variant READ-US 15 68583063 68583063 single base substitution A C missense_variant K456T 1367A>C READ-US 15 68583063 68583063 single base substitution A C missense_variant K97T 290A>C READ-US 15 68583077 68583077 single base substitution G A downstream_gene_variant READ-US 15 68583077 68583077 single base substitution G A missense_variant E102K 304G>A READ-US 15 68583077 68583077 single base substitution G A missense_variant E461K 1381G>A RECA-EU 15 68567412 68567412 single base substitution C T upstream_gene_variant RECA-EU 15 68571325 68571325 single base substitution C T intron_variant RECA-EU 15 68571325 68571325 single base substitution C T upstream_gene_variant RECA-EU 15 68583697 68583697 single base substitution A C 3_prime_UTR_variant RECA-EU 15 68583697 68583697 single base substitution A C downstream_gene_variant RECA-EU 15 68587071 68587071 single base substitution G A 3_prime_UTR_variant RECA-EU 15 68587071 68587071 single base substitution G A downstream_gene_variant RECA-EU 15 68589192 68589192 single base substitution A C downstream_gene_variant SKCA-BR 15 68574043 68574043 single base substitution C T intron_variant SKCA-BR 15 68574918 68574918 single base substitution T G intron_variant SKCA-BR 15 68580633 68580633 single base substitution T C intron_variant SKCA-BR 15 68580633 68580633 single base substitution T C upstream_gene_variant SKCA-BR 15 68581390 68581390 single base substitution T C intron_variant SKCA-BR 15 68581390 68581390 single base substitution T C upstream_gene_variant SKCA-BR 15 68584994 68584995 deletion of <=200bp TG - 3_prime_UTR_variant SKCA-BR 15 68584994 68584995 deletion of <=200bp TG - downstream_gene_variant SKCA-BR 15 68589770 68589770 insertion of <=200bp - CT downstream_gene_variant SKCA-BR 15 68591917 68591917 single base substitution G A downstream_gene_variant SKCA-BR 15 68592464 68592464 single base substitution C T downstream_gene_variant SKCA-BR 15 68592863 68592863 single base substitution C T downstream_gene_variant SKCM-US 15 68582855 68582855 single base substitution C T downstream_gene_variant SKCM-US 15 68582855 68582855 single base substitution C T intron_variant SKCM-US 15 68582855 68582855 single base substitution C T stop_gained R387* 1159C>T SKCM-US 15 68583223 68583223 single base substitution T C downstream_gene_variant SKCM-US 15 68583223 68583223 single base substitution T C synonymous_variant F150F 450T>C SKCM-US 15 68583223 68583223 single base substitution T C synonymous_variant F509F 1527T>C STAD-US 15 68582325 68582325 single base substitution G A downstream_gene_variant STAD-US 15 68582325 68582325 single base substitution G A missense_variant R210H 629G>A STAD-US 15 68582325 68582325 single base substitution G A missense_variant R52H 155G>A STAD-US 15 68582325 68582325 single base substitution G A upstream_gene_variant STAD-US 15 68582994 68582994 single base substitution T C downstream_gene_variant STAD-US 15 68582994 68582994 single base substitution T C intron_variant STAD-US 15 68582994 68582994 single base substitution T C missense_variant V433A 1298T>C STAD-US 15 68583129 68583129 single base substitution A T downstream_gene_variant STAD-US 15 68583129 68583129 single base substitution A T missense_variant D119V 356A>T STAD-US 15 68583129 68583129 single base substitution A T missense_variant D478V 1433A>T STAD-US 15 68583314 68583314 single base substitution G A downstream_gene_variant STAD-US 15 68583314 68583314 single base substitution G A missense_variant V181I 541G>A STAD-US 15 68583314 68583314 single base substitution G A missense_variant V540I 1618G>A STAD-US 15 68583466 68583466 single base substitution A C downstream_gene_variant STAD-US 15 68583466 68583466 single base substitution A C missense_variant K231N 693A>C STAD-US 15 68583466 68583466 single base substitution A C missense_variant K590N 1770A>C UCEC-US 15 68582151 68582151 single base substitution A G 5_prime_UTR_variant UCEC-US 15 68582151 68582151 single base substitution A G missense_variant K152R 455A>G UCEC-US 15 68582151 68582151 single base substitution A G upstream_gene_variant UCEC-US 15 68582322 68582322 single base substitution G T downstream_gene_variant UCEC-US 15 68582322 68582322 single base substitution G T missense_variant W209L 626G>T UCEC-US 15 68582322 68582322 single base substitution G T missense_variant W51L 152G>T UCEC-US 15 68582322 68582322 single base substitution G T upstream_gene_variant UCEC-US 15 68582610 68582610 single base substitution G T downstream_gene_variant UCEC-US 15 68582610 68582610 single base substitution G T missense_variant R20I 59G>T UCEC-US 15 68582610 68582610 single base substitution G T missense_variant R305I 914G>T UCEC-US 15 68582661 68582661 single base substitution A C downstream_gene_variant UCEC-US 15 68582661 68582661 single base substitution A C missense_variant D322A 965A>C UCEC-US 15 68582661 68582661 single base substitution A C missense_variant D37A 110A>C UCEC-US 15 68582856 68582856 single base substitution G A downstream_gene_variant UCEC-US 15 68582856 68582856 single base substitution G A intron_variant UCEC-US 15 68582856 68582856 single base substitution G A missense_variant R387Q 1160G>A UCEC-US 15 68583026 68583026 single base substitution C A downstream_gene_variant UCEC-US 15 68583026 68583026 single base substitution C A intron_variant UCEC-US 15 68583026 68583026 single base substitution C A missense_variant L444I 1330C>A UCEC-US 15 68583403 68583403 single base substitution G A downstream_gene_variant UCEC-US 15 68583403 68583403 single base substitution G A synonymous_variant T210T 630G>A UCEC-US 15 68583403 68583403 single base substitution G A synonymous_variant T569T 1707G>A

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand C84 COSM4620020 c.774C>T p.A258A Substitution - coding silent 15:68290132-68290132 + PD9759a COSM5772718 c.40G>A p.E14K Substitution - Missense 15:68278457-68278457 + TCGA-BR-4256-01 COSM1238886 c.629G>A p.R210H Substitution - Missense 15:68289987-68289987 + 2159320 COSM4167493 c.1178C>T p.S393L Substitution - Missense 15:68290536-68290536 + TCGA-F5-6814-01 COSM964343 c.914G>T p.R305I Substitution - Missense 15:68290272-68290272 + TCGA-AA-3510-01 COSM1374255 c.1439G>A p.R480K Substitution - Missense 15:68290797-68290797 + CH-LA9 COSM4166236 c.520_522delTTA p.L174delL Deletion - In frame 15:68289878-68289880 + TCGA-DK-A1A3-01 COSM416849 c.702C>T p.V234V Substitution - coding silent 15:68290060-68290060 + LUAD-RT-S01702 COSM379061 c.1515C>T p.D505D Substitution - coding silent 15:68290873-68290873 + TCGA-EE-A3AA-06 COSM701405 c.1159C>T p.R387* Substitution - Nonsense 15:68290517-68290517 + HCC74T COSM1608624 c.532G>T p.A178S Substitution - Missense 15:68289890-68289890 + ESCC-002T COSM2257846 c.873C>T p.L291L Substitution - coding silent 15:68290231-68290231 + WT011 COSM5351804 c.377G>A p.R126Q Substitution - Missense 15:68289735-68289735 + Pat_08_A COSM5849638 c.985C>T p.L329F Substitution - Missense 15:68290343-68290343 + 587222 COSM1206969 c.737G>A p.R246Q Substitution - Missense 15:68290095-68290095 + TCGA-D7-A4YV-01 COSM4056487 c.1618G>A p.V540I Substitution - Missense 15:68290976-68290976 + TCGA-IR-A3LB-01 COSM4829340 c.599T>G p.I200R Substitution - Missense 15:68289957-68289957 + TCGA-BP-4162-01 COSM3361500 c.571T>C p.L191L Substitution - coding silent 15:68289929-68289929 + 8047860 COSM4388609 c.141C>G p.S47S Substitution - coding silent 15:68278558-68278558 + CSCC-10-T COSM4470663 c.1675C>T p.L559L Substitution - coding silent 15:68291033-68291033 + TCGA-B0-5709-01 COSM470997 c.1139A>T p.N380I Substitution - Missense 15:68290497-68290497 + PD7306a COSM5788950 c.819C>A p.Y273* Substitution - Nonsense 15:68290177-68290177 + TCGA-C5-A7UH-01 COSM4856927 c.1299C>T p.V433V Substitution - coding silent 15:68290657-68290657 + TCGA-A6-2686-01 COSM5084647 c.1293T>C p.A431A Substitution - coding silent 15:68290651-68290651 + TCGA-43-5668-01 COSM701406 c.200A>G p.E67G Substitution - Missense 15:68278617-68278617 + pfg119T COSM4756902 c.538C>T p.P180S Substitution - Missense 15:68289896-68289896 + TCGA-BR-8680-01 COSM4056488 c.1770A>C p.K590N Substitution - Missense 15:68291128-68291128 + ESCC_170 COSM5649228 c.1455C>T p.F485F Substitution - coding silent 15:68290813-68290813 + TCGA-D5-6530-01 COSM2257845 c.628C>T p.R210C Substitution - Missense 15:68289986-68289986 + HCC063T COSM5812813 c.901G>T p.A301S Substitution - Missense 15:68290259-68290259 + T2269 COSM2257847 c.874G>A p.E292K Substitution - Missense 15:68290232-68290232 + TCGA-18-3406-01 COSM701405 c.1159C>T p.R387* Substitution - Nonsense 15:68290517-68290517 + TCGA-AY-A69D-01 COSM5137141 c.1582G>A p.V528M Substitution - Missense 15:68290940-68290940 + ESCC_41 COSM5629531 c.24A>G p.V8V Substitution - coding silent 15:68278441-68278441 + SC_9099 COSM5555552 c.132G>A p.G44G Substitution - coding silent 15:68278549-68278549 + TCGA-AD-A5EJ-01 COSM5133011 c.375G>A p.L125L Substitution - coding silent 15:68289733-68289733 + HCC2998 COSM2257847 c.874G>A p.E292K Substitution - Missense 15:68290232-68290232 + TCGA-B5-A0JY-01 COSM964343 c.914G>T p.R305I Substitution - Missense 15:68290272-68290272 + ccRCC-68 COSM1661834 c.1585G>C p.D529H Substitution - Missense 15:68290943-68290943 + TCGA-AA-3712-01 COSM1374253 c.679G>A p.A227T Substitution - Missense 15:68290037-68290037 + TCGA-D5-6530-01 COSM5162344 c.985C>A p.L329I Substitution - Missense 15:68290343-68290343 + TCGA-A6-5665-01 COSM5089852 c.663G>A p.T221T Substitution - coding silent 15:68290021-68290021 + TCGA-EJ-7125-01 COSM3672101 c.790C>A p.R264S Substitution - Missense 15:68290148-68290148 + TCGA-AD-6889-01 COSM1374254 c.736C>A p.R246R Substitution - coding silent 15:68290094-68290094 + ESO-081 COSM1243265 c.1807C>A p.R603R Substitution - coding silent 15:68291165-68291165 + TCGA-C5-A1BI-01 COSM4841527 c.1444C>T p.R482C Substitution - Missense 15:68290802-68290802 + ESO-859 COSM1238885 c.376C>T p.R126W Substitution - Missense 15:68289734-68289734 + TCGA-DA-A1HV-06 COSM701405 c.1159C>T p.R387* Substitution - Nonsense 15:68290517-68290517 + Pat_08_B COSM5849638 c.985C>T p.L329F Substitution - Missense 15:68290343-68290343 + ESO-859 COSM1238886 c.629G>A p.R210H Substitution - Missense 15:68289987-68289987 + C004 COSM5521659 c.1228G>A p.V410I Substitution - Missense 15:68290586-68290586 + Detroit_562 COSM4595170 c.1479T>C p.N493N Substitution - coding silent 15:68290837-68290837 + TCGA-22-5473-01 COSM701404 c.1233G>C p.L411F Substitution - Missense 15:68290591-68290591 + HCC74 COSM1608624 c.532G>T p.A178S Substitution - Missense 15:68289890-68289890 + TCGA-D1-A16N-01 COSM964345 c.1001G>A p.R334Q Substitution - Missense 15:68290359-68290359 + TCGA-FU-A3HZ-01 COSM3420559 c.1381G>A p.E461K Substitution - Missense 15:68290739-68290739 + 041T COSM1729087 c.1883A>T p.*628L Nonstop extension 15:68291241-68291241 + TCGA-AP-A056-01 COSM964346 c.1160G>A p.R387Q Substitution - Missense 15:68290518-68290518 + TCGA-EE-A3AB-06 COSM3503449 c.1527T>C p.F509F Substitution - coding silent 15:68290885-68290885 + YUKAT COSM5383739 c.1435C>T p.P479S Substitution - Missense 15:68290793-68290793 + HCC2998 COSM1678553 c.1150G>A p.D384N Substitution - Missense 15:68290508-68290508 + SH-1537 COSM5017972 c.1506C>T p.H502H Substitution - coding silent 15:68290864-68290864 + 8069156 COSM3771874 c.1119C>T p.L373L Substitution - coding silent 15:68290477-68290477 + 587342 COSM1206970 c.106C>A p.L36I Substitution - Missense 15:68278523-68278523 + TCGA-B5-A11E-01 COSM964344 c.965A>C p.D322A Substitution - Missense 15:68290323-68290323 + 6115114 COSM5565156 c.736C>T p.R246* Substitution - Nonsense 15:68290094-68290094 + 041T COSM1729086 c.961A>T p.R321* Substitution - Nonsense 15:68290319-68290319 + CHC1209T COSM4804694 c.43G>A p.G15S Substitution - Missense 15:68278460-68278460 + TCGA-B5-A0JY-01 COSM964342 c.626G>T p.W209L Substitution - Missense 15:68289984-68289984 + TCGA-LP-A4AV-01 COSM4825041 c.365C>T p.S122L Substitution - Missense 15:68289723-68289723 + ORL-48 COSM4596475 c.499A>G p.T167A Substitution - Missense 15:68289857-68289857 + A3 COSM5350282 c.846G>A p.E282E Substitution - coding silent 15:68290204-68290204 + TCGA-BS-A0UV-01 COSM964341 c.455A>G p.K152R Substitution - Missense 15:68289813-68289813 + HCC2998 COSM1678553 c.1150G>A p.D384N Substitution - Missense 15:68290508-68290508 + HCT116 COSM1678552 c.607G>A p.V203M Substitution - Missense 15:68289965-68289965 + TCGA-DY-A1DC-01 COSM1562830 c.1367A>C p.K456T Substitution - Missense 15:68290725-68290725 + HCT-116 COSM1678552 c.607G>A p.V203M Substitution - Missense 15:68289965-68289965 + HCC089T COSM5822392 c.459T>C p.Y153Y Substitution - coding silent 15:68289817-68289817 + DN11197 COSM5788950 c.819C>A p.Y273* Substitution - Nonsense 15:68290177-68290177 + OV207 COSM252998 c.1381_1383delGAA p.E461delE Deletion - In frame 15:68290739-68290741 + TCGA-EI-6917-01 COSM3420559 c.1381G>A p.E461K Substitution - Missense 15:68290739-68290739 + CHC1209T COSM4804694 c.43G>A p.G15S Substitution - Missense 15:68278460-68278460 + TCGA-BS-A0UV-01 COSM964348 c.1707G>A p.T569T Substitution - coding silent 15:68291065-68291065 + TCGA-BR-6802-01 COSM4056485 c.1298T>C p.V433A Substitution - Missense 15:68290656-68290656 + TCGA-CM-6162-01 COSM1374252 c.662C>T p.T221M Substitution - Missense 15:68290020-68290020 + Pat_41_B COSM5849639 c.1537C>T p.L513F Substitution - Missense 15:68290895-68290895 + TCGA-BH-A0HB-01 COSM434206 c.653A>T p.H218L Substitution - Missense 15:68290011-68290011 + 2492729 COSM5727031 c.802G>A p.D268N Substitution - Missense 15:68290160-68290160 + I2L-P7-Tumor-Organoid COSM5363078 c.146C>A p.P49H Substitution - Missense 15:68278563-68278563 + TCGA-E2-A15J-01 COSM434207 c.1173T>A p.V391V Substitution - coding silent 15:68290531-68290531 + TCGA-EK-A3GK-01 COSM4854216 c.324C>A p.V108V Substitution - coding silent 15:68289682-68289682 + TCGA-B8-5162-01 COSM1493455 c.932C>A p.P311H Substitution - Missense 15:68290290-68290290 + TCGA-AP-A0LM-01 COSM964347 c.1330C>A p.L444I Substitution - Missense 15:68290688-68290688 + Pat_63_B COSM5849637 c.350C>T p.T117I Substitution - Missense 15:68289708-68289708 + PD5942a COSM5785308 c.1137G>C p.R379S Substitution - Missense 15:68290495-68290495 + TCGA-CG-5723-01 COSM4056486 c.1433A>T p.D478V Substitution - Missense 15:68290791-68290791 + TCGA-AY-4070-01 COSM301260 c.1863A>G p.E621E Substitution - coding silent 15:68291221-68291221 + Pat_01_A COSM5849640 c.1644delT p.L550fs*1 Deletion - Frameshift 15:68291002-68291002 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.362733 15q22 613539

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.E561A c.1682A>C 15 68583378 LUAD A G 3-UTRSNV . c.1881+2197A>G 15 68585774 HC A G 3-UTRSNV . c.1881+2336A>G 15 68585913 HC A G Missense p.E67G c.200A>G 15 68570955 LUSC A G Missense p.H110R c.329A>G 15 68582025 HNSC A G Synonymous p.E621E c.1863A>G 15 68583559 COREAD A T Missense p.H218L c.653A>T 15 68582349 BRCA A T Missense p.N380I c.1139A>T 15 68582835 RCCC C G Missense p.P497A c.1489C>G 15 68583185 BRCA C T Missense p.P180S c.538C>T 15 68582234 CM C T Nonsense p.R387* c.1159C>T 15 68582855 CM C T Nonsense p.R387* c.1159C>T 15 68582855 LUSC C T Synonymous p.V234V c.702C>T 15 68582398 BLCA G A Synonymous p.A355A c.1065G>A 15 68582761 STAD G C Missense p.L411F c.1233G>C 15 68582929 LUSC G T Missense p.G44V c.131G>T 15 68570886 LUAD T A 3-UTRSNV . c.1881+2573T>A 15 68586150 MB T A Synonymous p.V391V c.1173T>A 15 68582869 BRCA T C Missense p.V433A c.1298T>C 15 68582994 STAD T C Synonymous p.F509F c.1527T>C 15 68583223 CM T C Synonymous p.L191L c.571T>C 15 68582267 RCCC