PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ALDH1B1 FEM1B 26186194 biogrid exp GP P G GP GP G GP GP GP GP P GP GP GP GP G P GP GP GP GP GP GP G GLI1 FEM1B 24076122 biogrid exp GP G G G P G G GP P P P G GP GP GP P P G P GP GP GP G CHEK1 FEM1B 19330022 biogrid exp G G G GP RAD9A FEM1B 19330022 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G MVB12B FEM1B 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G FEM1B COPS3 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FEM1B FEM1B 10542291 hprd exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G HIF1AN FEM1B 17003112 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G DMWD FEM1B 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COPS4 FEM1B 19295130 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G COPS6 FEM1B 26186194,19615732,21145461 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP G GP G GP GP G KIAA0319 FEM1B 12421765 hprd,biogrid,i2d,intact exp P P G GP G P P G P P P P GP P P G P P P P P P P EPN3 FEM1B 26186194 biogrid exp GP P P G G GP GP P P GP P GP P GP GP GP GP P GNB2L1 FEM1B 19855191 biogrid exp P P P P P P P P P P P P P P P P PPM1F FEM1B 11559703 biogrid,mint,intact exp GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP P G WNT3A FEM1B 26186194 biogrid exp P P P P P P P P P TGFB1 FEM1B 26186194 biogrid exp G G G G GP G G G G G G G G G G GP G G G G GP G G GP G GP G G GAK FEM1B 26496610 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G FAS FEM1B 10542291 hprd,bci exp GP GP G G G GP G G GP GP G GP G G GP GP G GP G GP GP G G GP G GP GP G APAF1 FEM1B 10764728 hprd exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CAMKMT FEM1B 26186194 biogrid exp G G G G G G G G G G G G G G G G G HTT FEM1B 23275563 intact exp GP GP G G GP GP G G GP G P GP P G G GP GP GP P G GP GP GP G GP G GP GP COPS2 FEM1B 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G NKX3-1 FEM1B 18816836, 23023127, 21836163 biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G NEDD8 FEM1B 21145461, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G DCUN1D1 FEM1B 21145461, 25402006 biogrid exp, pred P G G G GP G P P G P P P P GP G GP G GP GP P GP GP P GP G COPS5 FEM1B 21145461, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CUL2 FEM1B 18187417,15601820,21145461, 25402006 innatedb,biogrid,intact exp, pred GP GP G G G GP G G GP G GP GP GP G G G GP GP GP G GP GP GP G G G GP GP G TCEB2 FEM1B 18187417,15601820, 25402006 innatedb,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBX1 FEM1B 15601820, 25402006 innatedb,biogrid,intact exp, pred G G G G G GP G GP G G G G GP G G G GP G GP G GP GP G G G G G GP G TCEB1 FEM1B 19855191,18187417,15601820, 25402006 innatedb,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL5 FEM1B 18187417,21145461, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SOS1 FEM1B ortho GP G G G GP G G GP GP G GP G GP G G GP G G GP G GP GP GP GP GP G GP G G KATNAL1 FEM1B ortho GP GP G G G GP G GP GP G GP GP GP G G GP GP GP P G GP GP G GP G GP GP G SMARCD1 FEM1B ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ADCY5 FEM1B ortho P G GP G G P G P P G G GP G G G P GP P G GP P G ACOX1 FEM1B ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G GYG1 FEM1B ortho G G G G G GP G G G G GP G G G G G GP GP GP G G G G GP G G G GP G KCTD5 FEM1B ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BANF1 FEM1B ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ANKRD37 FEM1B ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G RAP2B FEM1B ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LYPLAL1 FEM1B ortho GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ATG5 FEM1B 16082366 ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FEM1B HECTD1 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G BCOR FEM1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G TRAF7 FEM1B 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G CASP6 FEM1B 23023127 pred GP G G GP G G GP GP G G G G GP GP GP P GP GP GP G GP G CDKN2C FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP G GP GP G GATA6 FEM1B 23023127 pred GP GP P P GP GP P GP GP G G GP P GP GP GP GP P P GP G GP GP G GZF1 FEM1B 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP G G GP GP G G GP G Fos39347_1 FEM1B 25402006 pred NOTCH4 FEM1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CASP1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SPSB2 FEM1B 25402006 pred GP GP G G G GP G G P G GP GP GP G GP GP G GP G GP GP G GP G GP GP G UBXN7 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G NFKB1 FEM1B 23023127 pred GP G G G GP G G G GP G G G GP G G GP G G G G GP GP GP G GP G G GP G COMMD1 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G TGFBR2 FEM1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CASP8 FEM1B 23023127 pred GP GP G GP P GP GP GP GP GP G G GP P GP P G GP GP GP P GP G GP GP G SOCS2 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G MED8 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G PLK1 FEM1B 23023127 pred P P G G GP P G GP GP P P P G GP GP GP GP G GP P GP GP GP P GP FEM1B RNF6 23023127 pred G GP G G GP GP G G GP G GP G GP G G GP GP G G G GP G G G GP G GP GP G NOTCH2 FEM1B 23023127 pred G GP G G G G G G GP G G G G G G G G G G G G G G G G G GP G G SPSB4 FEM1B 25402006 pred G MIB2 FEM1B 23023127 pred P P G GP G GP P G GP P P P GP GP GP G GP GP GP GP GP P P G SOCS4 FEM1B 25402006 pred GP GP G G GP GP G G GP G GP G GP G G GP GP G G G GP GP GP GP GP G GP GP G TP63 FEM1B 23023127 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G SOCS1 FEM1B 25402006 pred GP GP P P GP GP GP GP GP G G GP P GP GP G GP P GP P GP G GP GP G FBXW8 FEM1B 25402006 pred P P P P P P P P P P P P P P P P P P P EGFR FEM1B 23023127 pred GP GP G GP G G GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G FEM1B TRPV2 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G G GP GP GP G GP GP GP G G G P G STK17A FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G UBE2M FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G GP GP GP G GP GP G ELF3 FEM1B 23023127 pred GP G G G G G G G GP G GP G G G G GP G G GP G GP G GP G GP G GP G G CUL4A FEM1B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIB1 FEM1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CAND1 FEM1B 25402006 pred G GP G G G G G G GP G GP GP G G G GP G GP G G G G GP GP GP G G GP G LRRC41 FEM1B 25402006 pred G G G G GP G G GP GP G GP G GP G G GP G G GP G GP G G GP GP G GP GP G LIMK1 FEM1B 23023127 pred P GP P GP G P P G P P P P GP P GP G P P P P P P NOTCH1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SKP1 FEM1B 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP G GP G GP GP G AKT1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ACVR1 FEM1B 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP G GP GP G GP GP G FEM1B PLXND1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G MAP3K7 FEM1B 23023127 pred GP GP G G G GP G G GP G G GP GP G G G GP G GP G GP GP G G G G GP GP G HOXD13 FEM1B 23023127 pred G MIB1 FEM1B 23023127 pred GP GP G G GP GP G G GP G GP GP G G G GP GP GP GP G GP GP GP G GP G GP GP G RECK FEM1B 23023127 pred GP G G G GP GP G GP GP G GP GP GP G G G GP GP G G GP G G G G G G GP G SPSB1 FEM1B 25402006 pred GP GP G G GP GP G GP G G GP GP GP G G G GP G GP G GP GP G GP G GP GP G FBXO31 FEM1B 25402006 pred GP GP G P GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G CSDE1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CUL7 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G RBPJ FEM1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FBXO18 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G AGRN FEM1B 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G VHL FEM1B 25402006 pred G G G G G G G G G G GP GP GP G G G G G P G G GP GP G G G G GP G ZDHHC17 FEM1B 23023127 pred G GP G G GP GP G G GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G NRCAM FEM1B 23023127 pred GP GP G P GP G P GP G G GP G P GP GP G GP GP P GP G P GP TRIB3 FEM1B 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G RELA FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FEM1B PRPF19 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G TP53 FEM1B 23023127 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G TNC FEM1B 23023127 pred GP GP G G G GP G G GP G GP G G G GP GP G GP GP GP G GP G GP GP G FEM1C FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G FEM1B USP20 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SOCS5 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G BARD1 FEM1B 23023127 pred P G GP P P GP P P P G G GP P G P P GP P GP P G GP GP G TGFB1I1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G GATA5 FEM1B 23023127 pred G G G G G PATZ1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CUL1 FEM1B 25402006 pred GP G G G G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SKP2 FEM1B 25402006 pred GP GP G G GP GP G GP GP G G GP GP G G GP GP G GP G GP G G GP GP G GP GP G CUL3 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CDKN2B FEM1B 23023127 pred GP P GP P P G G GP P G P GP G ANKRD39 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G GP GP GP GP G P GP GP GP GP G GP GP G FEM1A FEM1B 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP G G G G GP GP GP G GP GP G CASP3 FEM1B 23023127 pred GP G G G GP G G GP G G G GP G G GP G G GP G GP G G G GP G GP GP G ETS1 FEM1B 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G G G CUL4B FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP GP G FAF2 FEM1B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD10 FEM1B 23023127 pred GP G G G G GP G G GP G G G GP G G GP GP GP GP G GP GP GP G GP G GP GP G TRIM21 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G FEM1B NOTCH3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ASZ1 FEM1B 23023127 pred P P P P P P GP RAB40C FEM1B 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G ANKRD7 FEM1B 23023127 pred P P P P P P P P P P P P P P P P P GP IGF1R FEM1B 23023127 pred GP GP G G G G G GP GP G GP GP GP G G GP G G GP G GP GP GP G GP G GP GP G DAPK1 FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ILK FEM1B 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G LRR1 FEM1B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G FEM1B INVS 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G CDC34 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G SOCS3 FEM1B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G GP GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UK73 - 12421765 - X 2 Q99801 Q9UK73 two hybrid 18816836 direct interaction X 2 P25118 Q9UK73 affinity chromatography technology 10542291 physical association X 2 Q9UK73 Q15370-2 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q15370-2 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q7L5N1 affinity chromatography technology 21145461 physical association X 2 Q9UK73 Q15843 affinity chromatography technology 21145461 physical association X 2 Q9UK73 pull down 19330022 direct interaction X 2 Q9UK73 Q9BT78 affinity chromatography technology 19295130 physical association X 2 Q9UK73 P70677 enzymatic study 10542291 direct interaction X 2 Q9UK73 P62877 affinity chromatography technology 15601820 physical association X 2 Q9UK73 Q15370-2 affinity chromatography technology 15601820 physical association X 2 Q9UK73 P49594 affinity chromatography technology 11559703 physical association X 2 Q9UK73 Q9NWT6 two hybrid 17003112 direct interaction X 2 Q9UK73 Q7L5N1 affinity chromatography technology 19615732 physical association X 2 Q9WVR7 Q9UK73 affinity chromatography technology 11559703 physical association X 2 A0A024R7W9 Q9UK73 affinity chromatography technology 21145461 physical association X 2 P0CG48 Q9UK73 affinity chromatography technology 22053931 physical association X 2 P0CG48 Q9UK73 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q9UK73 affinity chromatography technology 19855191 physical association X 2 P0CG48 Q9UK73 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q9UK73 affinity chromatography technology 21890473 physical association X 2 Q9UK73 Q15369-2 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q13617 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q93034 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q15369-2 affinity chromatography technology 18187417 physical association X 2 Q9UK73 Q93034 affinity chromatography technology 21145461 physical association X 2 Q9UK73 Q13617 affinity chromatography technology 21145461 physical association X 2 Q9UK73 Q96GG9 affinity chromatography technology 21145461 physical association X 2 Q9UK73 B4DT73 affinity chromatography technology 19330022 physical association X 2 Q9UK73 B4DT73 affinity chromatography technology 19330022 physical association X 2 Q9UK73 P25446 two hybrid 10542291 direct interaction X 2 Q9UK73 Q9Z2G0 affinity chromatography technology 10542291 physical association X 2 Q9UK73 P25446 affinity chromatography technology 10542291 physical association X 2 Q9UK73 Q13617 affinity chromatography technology 15601820 physical association X 2 Q9UK73 Q13617 affinity chromatography technology 15601820 physical association X 2 Q9UK73 Q15369-2 affinity chromatography technology 15601820 physical association X 2 Q9UK73 P08151 affinity chromatography technology 24076122 physical association X 2 Q9UK73 P08151 pull down 24076122 direct interaction X 2 Q9UK73 Q15369-2 affinity chromatography technology 19855191 physical association X 2 Q9UK73 Q5VV43 two hybrid 12421765 direct interaction X 2 P49593 Q9UK73 affinity chromatography technology 11559703 physical association X 2 P49593 Q9UK73 pull down 11559703 direct interaction X 2 E9KL35 Q9UK73 affinity chromatography technology 19855191 physical association X 2 E9KL35 Q9UK73 affinity chromatography technology 19855191 physical association X 2 Q9UK73 O14727-3 in vivo 10764728 - X 2 Q9UK73 O14727-3 in vitro 10764728 - X 2 Q9UK73 O14727-3 in vivo 10764728 - X 2 Q9UK73 O14727-3 in vitro 10764728 - X 2 Q9UK73 P25445-2 in vivo 10542291 - X 2 Q9UK73 P25445-2 two hybrid 10542291 - X 2 Q9UK73 P25445-2 in vitro 10542291 - X 2 Q9UK73 Q5VV43 two hybrid 12421765 - X 2 Q9UK73 Q9UK73 in vivo 10542291 - X 2 Q9UK73 Q9UK73 in vitro 10542291 - X 2 Q9UK73 P25445-2 in vivo 10542291 - X 2 Q9UK73 P25445-2 in vitro 10542291 - X 2 Q9UK73 P25445-2 two hybrid 10542291 - X 2 Q9UK73 Q5VV43 two hybrid 12421765 - X 2 Q9UK73 anti tag coimmunoprecipitation 15601820 association C 7 P42858 Q9UK73 luminescence based mammalian interactome mapping 23275563 physical association X 2 Q9UK73 Q7CL32 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q7CHP0 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q8ZH09 two hybrid pooling approach 20711500 physical association X 2 Q81SN0 Q9UK73 two hybrid pooling approach 20711500 physical association X 2 Q7CJQ8 Q9UK73 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 anti tag coimmunoprecipitation 15601820 association C 5 Q9UK73 anti tag coimmunoprecipitation 15601820 association C 5 Q9UK73 anti tag coimmunoprecipitation 19615732 physical association C 55 Q81V35 Q9UK73 two hybrid pooling approach 20711500 physical association X 2 Q7CHR9 Q9UK73 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q5VV43 two hybrid 12421765 physical association X 2 Q9UK73 Q81T35 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q7CKY1 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q7CKU7 two hybrid pooling approach 20711500 physical association X 2 Q9UK73 Q8X3G1 two hybrid 25519916 physical association X 2 P49593 Q9UK73 pull down 11559703 direct interaction X 2 P49593 Q9UK73 anti tag coimmunoprecipitation 11559703 physical association X 2 Q81JM0 Q9UK73 two hybrid pooling approach 20711500 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality GAK FEM1B 26496610,26496610 0007,0004 HT TGFB1 FEM1B 26186194 0004 HT ALDH1B1 FEM1B 26186194 0004 HT WNT3A FEM1B 26186194 0004 HT DMWD FEM1B 26186194 0004 HT CUL2 FEM1B 15601820,21145461,18187417,15601820 0004,0004,0004,0007 LC,HT TCEB1 FEM1B 19855191,15601820,15601820,18187417 0004,0004,0007,0004 LC TCEB2 FEM1B 15601820,15601820,18187417 0004,0007,0004 LC NEDD8 FEM1B 21145461 0004 HT Q59EL2 FEM1B 26186194 0004 HT COPS6 FEM1B 26186194,19615732,21145461,19615732 0004,0004,0004,0007 HT CAMKMT FEM1B 26186194 0004 HT COPS5 FEM1B 21145461 0004 HT CUL5 FEM1B 21145461,18187417 0004,0004 HT,LC DCUN1D1 FEM1B 21145461 0004 HT EPN3 FEM1B 26186194 0004 HT MVB12B FEM1B 26186194 0004 HT FEM1B COPS3 26186194 0004 HT GAK FEM1B 26496610,26496610 0007,0004 HT TGFB1 FEM1B 26186194 0004 HT ALDH1B1 FEM1B 26186194 0004 HT WNT3A FEM1B 26186194 0004 HT DMWD FEM1B 26186194 0004 HT CUL2 FEM1B 21145461 0004 HT NEDD8 FEM1B 21145461 0004 HT Q59EL2 FEM1B 26186194 0004 HT COPS6 FEM1B 26186194,19615732,21145461,19615732 0004,0004,0004,0007 HT CAMKMT FEM1B 26186194 0004 HT COPS5 FEM1B 21145461 0004 HT CUL5 FEM1B 21145461 0004 HT DCUN1D1 FEM1B 21145461 0004 HT EPN3 FEM1B 26186194 0004 HT MVB12B FEM1B 26186194 0004 HT FEM1B COPS3 26186194 0004 HT CUL2 FEM1B 15601820,18187417,15601820 0004,0004,0007 LC TCEB1 FEM1B 19855191,15601820,15601820,18187417 0004,0004,0007,0004 LC TCEB2 FEM1B 15601820,15601820,18187417 0004,0007,0004 LC CUL5 FEM1B 18187417 0004 LC FAS FEM1B 10542291 0018 LC HTT FEM1B 23275563 0729 HT KIAA0319 FEM1B 12421765 0018 HT NKX3-1 FEM1B 18816836 0018 LC HIF1AN FEM1B 17003112,17003112,17003112 0007,0018,1000 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UK73 P56704 FEM1B WNT3A 0.126 26186194 Q9UK73 O14976 FEM1B GAK 0.126 26496610 Q9UK73 P61201 FEM1B COPS2 0.126 26186194 Q9UK73 P25118 FEM1B TNFRSF1A 0.21 10542291 Q9UK73 Q9H7P6 FEM1B MVB12B 0.126 26186194 Q9UK73 Q9NWT6 FEM1B HIF1AN 0.309 17003112 Q9UK73 Q9H201 FEM1B EPN3 0.126 26186194 Q9WVR7 Q9UK73 PPM1F FEM1B 0.21 11559703 Q9Z2G0 Q9UK73 FEM1B FEM1B 0.21 10542291 Q9UK73 Q7CL32 FEM1B Q7CL32 0.126 20711500 Q9UK73 Q7Z624 FEM1B CAMKMT 0.126 26186194 Q9UK73 Q81JM0 FEM1B Q81JM0 0.126 20711500 Q9UK73 Q81SN0 FEM1B Q81SN0 0.126 20711500 Q9UK73 Q81V35 FEM1B RBSC 0.126 20711500 Q9UK73 P01137 FEM1B TGFB1 0.126 26186194 Q9UK73 P62877 FEM1B RBX1 0.236 15601820 Q9UK73 P25446 FEM1B FAS 0.454 10542291 Q9UK73 Q13617 FEM1B CUL2 0.554 18187417,21145461,15601820 Q9UK73 Q7L5N1 FEM1B COPS6 0.416 21145461,26186194,19615732 Q9UK73 Q92905 FEM1B COPS5 0.126 21145461 Q9UK73 Q93034 FEM1B CUL5 0.236 18187417,21145461 Q9UK73 P30837 FEM1B ALDH1B1 0.126 26186194 Q9UK73 Q96GG9 FEM1B DCUN1D1 0.126 21145461 Q9UK73 Q9BT78 FEM1B COPS4 0.126 19295130 Q9UK73 Q99801 FEM1B NKX3-1 0.309 18816836 Q9UK73 O14757 FEM1B CHEK1 0.376 19330022 Q9UK73 P08151 FEM1B GLI1 0.454 24076122 Q9UK73 P42858 FEM1B HTT 0.126 23275563 Q9UK73 P49593 FEM1B PPM1F 0.569 11559703 Q9UK73 P63244 FEM1B GNB2L1 0.376 19855191 Q9UK73 Q5VV43 FEM1B KIAA0319 0.332 12421765 Q9UK73 Q7CHP0 FEM1B Q7CHP0 0.126 20711500 Q9UK73 Q7CHR9 FEM1B YSUR 0.126 20711500 Q9UK73 Q7CJQ8 FEM1B RSEA 0.126 20711500 Q9UK73 Q7CKU7 FEM1B HEMB 0.126 20711500 Q9UK73 Q7CKY1 FEM1B PAAI2 0.126 20711500 Q9UK73 Q81T35 FEM1B Q81T35 0.126 20711500 Q9UK73 Q8ZH09 FEM1B NADK 0.126 20711500 Q9UK73 Q99638 FEM1B RAD9A 0.309 19330022 Q9UNS2 Q9UK73 COPS3 FEM1B 0.126 26186194 Q9UK73 P70677 FEM1B CASP3 0.309 10542291 Q9UK73 P49594 FEM1B FEM-2 0.21 11559703 Q9UK73 A0A0H3JFN8 FEM1B A0A0H3JFN8 0.183 25519916 Q9UK73 Q15369 FEM1B TCEB1 0.539 18187417,15601820,19855191 Q9UK73 Q15370 FEM1B TCEB2 0.416 18187417,15601820 Q9UK73 Q15843 FEM1B NEDD8 0.126 21145461 Q9UK73 Q09019 FEM1B DMWD 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CHEK1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database GAK FEM1B MI:0045 experimental interaction detection MI:0461 interaction database ADCY6 FEM1B MI:0362 inference MI:0461 interaction database BANF1 FEM1B MI:0362 inference MI:0461 interaction database ADCY5 FEM1B MI:0362 inference MI:0461 interaction database TGFB1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database GLI1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database UBC FEM1B MI:0045 experimental interaction detection MI:0461 interaction database RAP2A FEM1B MI:0362 inference MI:0461 interaction database TNFRSF1A FEM1B MI:0362 inference MI:0461 interaction database TAF1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database FAS FEM1B MI:0362 inference MI:0461 interaction database ALDH1B1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database HNF4A FEM1B MI:0045 experimental interaction detection MI:0461 interaction database CASP3 FEM1B MI:0362 inference MI:0461 interaction database HTT FEM1B MI:0045 experimental interaction detection MI:0461 interaction database PPM1F FEM1B MI:0045 experimental interaction detection MI:0461 interaction database WNT3A FEM1B MI:0045 experimental interaction detection MI:0461 interaction database COPS2 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database RAP2B FEM1B MI:0362 inference MI:0461 interaction database RBX1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database RACK1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database SOS1 FEM1B MI:0362 inference MI:0461 interaction database SOS2 FEM1B MI:0362 inference MI:0461 interaction database DMWD FEM1B MI:0045 experimental interaction detection MI:0461 interaction database CUL2 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database ACOX1 FEM1B MI:0362 inference MI:0461 interaction database TCEB1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database TCEB2 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database NEDD8 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database KIAA0319 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database LYPLAL1 FEM1B MI:0362 inference MI:0461 interaction database SMARCD3 FEM1B MI:0362 inference MI:0461 interaction database COPS6 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database CAMKMT FEM1B MI:0045 experimental interaction detection MI:0461 interaction database ANKRD37 FEM1B MI:0362 inference MI:0461 interaction database COPS5 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database SMARCD2 FEM1B MI:0362 inference MI:0461 interaction database CUL5 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database FBXW7 FEM1B MI:0362 inference MI:0461 interaction database DCUN1D1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database SMARCD1 FEM1B MI:0362 inference MI:0461 interaction database RAD9A FEM1B MI:0045 experimental interaction detection MI:0461 interaction database NKX3-1 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database COPS4 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database CHAC1 FEM1B MI:0362 inference MI:0461 interaction database PARD6G FEM1B MI:0362 inference MI:0461 interaction database ATG5 FEM1B MI:0362 inference MI:0461 interaction database EPN3 FEM1B MI:0045 experimental interaction detection MI:0461 interaction database MVB12B FEM1B MI:0045 experimental interaction detection MI:0461 interaction database PARD6A FEM1B MI:0362 inference MI:0461 interaction database HIF1AN FEM1B MI:0045 experimental interaction detection MI:0461 interaction database KCTD5 FEM1B MI:0362 inference MI:0461 interaction database FEM1B COPS3 MI:0045 experimental interaction detection MI:0461 interaction database FEM1B SSX2IP MI:0362 inference MI:0461 interaction database FEM1B RAP2C MI:0362 inference MI:0461 interaction database FEM1B ZNF706 MI:0362 inference MI:0461 interaction database