PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PKM MAP3K2 24606918 intact exp G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G GTF2IRD1 MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FUS MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PAF1 MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G MAPKAP1 MAP3K2 15988011 innatedb exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G USP2 MAP3K2 24975362 biogrid exp GP G GP G GP P G GP GP G G P GP G G G GP P GP GP GP P GP G ANKHD1 MAP3K2 20936779 i2d exp G GP G G GP G GP GP G GP GP G G G GP GP G G GP GP GP GP GP G GP GP G MAP3K2 MAP3K2 24975362,17906693,9162092,11343802,15001576,17721511 innatedb,biogrid,i2d,intact exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PIBF1 MAP3K2 20936779 biogrid,i2d exp G G G G G G G G G G G G G G G G G G G G G G G HNRNPA2B1 MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G EPS8 MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G NFKBIA MAP3K2 10085062 hprd exp G GP G G G GP G GP GP G G G G G G GP GP G G G GP GP GP GP GP G GP GP G ZNF277 MAP3K2 20936779 i2d exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G NEDD4L MAP3K2 19953087 biogrid exp G GP G GP G GP GP G GP G G G GP GP G G G GP GP G G GP G GP G STX3 MAP3K2 26496610 biogrid,intact exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G STAMBP MAP3K2 24975362 biogrid exp G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G NEDD4 MAP3K2 19953087 biogrid exp G GP G G P G GP GP GP G G G G GP GP G G G GP GP GP GP GP G GP P G UBC MAP3K2 20588253 mint,intact exp, ortho G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP2K5 MAP3K2 24975362,21988832,19903815,11073940, 25402006, 23023127, 21836163 hprd,biogrid,intact exp, ortho, pred G GP G G G GP G GP GP G GP P G G G GP GP G G P GP GP GP GP G GP GP G SMURF1 MAP3K2 19318350,15820682, 25402006 hprd,biogrid exp, ortho, pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G G GP G XIAP MAP3K2 24975362,18761086, 25402006 biogrid,intact exp, ortho, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G GP GP G GP G GP GP G STUB1 MAP3K2 20588253, 25402006 biogrid,mint,intact exp, ortho, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SH2D2A MAP3K2 11073940,12640115, 25402006 hprd,biogrid exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 MAP3K2 26496610, 25402006 biogrid,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G G GP GP GP G GP GP G YWHAE MAP3K2 9452471,26496610,17979178, 25402006 hprd,biogrid,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G YWHAH MAP3K2 17979178, 25402006 intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK8 MAP3K2 10713157, 25402006, 23023127, 21836163, 16082366 innatedb,hprd,biogrid exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K5 MAP3K2 12912994, 25402006, 23023127, 21836163, 16082366 hprd,mint exp, pred G GP G G G GP G G GP G GP G G G G G GP G G G G GP G G G G GP GP G MAP2K7 MAP3K2 24975362,10713157,9372971, 25402006, 23023127 innatedb,hprd,biogrid,i2d exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G MAP2K3 MAP3K2 9162092, 25402006 biogrid exp, pred P P P P P P P P P P P P P P PKN2 MAP3K2 10818102,12640115, 25402006 hprd exp, pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K2 IKBKG 20098747, 25402006 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HSP90AA1 MAP3K2 22939624, 25402006, 16082366 biogrid exp, pred G GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G MAPK7 MAP3K2 24975362, 25402006, 23023127 biogrid exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP P GP G GP GP G YWHAZ MAP3K2 9452471,26496610, 25402006 hprd,biogrid,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K3 MAP3K2 24975362,26496610,14743216, 25402006, 23023127, 16082366 biogrid,mint,intact exp, pred G G G G G GP G GP G G GP G G G G GP GP G G G GP G G G GP G GP G G STK38 MAP3K2 17906693, 23023127 biogrid exp, pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G YWHAG MAP3K2 15324660,26496610, 25402006 hprd,biogrid,mint,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SFN MAP3K2 15778465,26496610, 25402006 biogrid,mint,intact exp, pred G G G G G G G G G G G G G G G G G G G G G GP G G G G G G G WNK1 MAP3K2 14681216, 21836163 hprd exp, pred G GP G G G GP G GP GP G GP GP G G G G GP G G G G G G GP G G G GP G BIRC2 MAP3K2 24975362, 25402006 biogrid exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G YWHAQ MAP3K2 26496610, 25402006 biogrid,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G HSP90AB1 MAP3K2 22939624, 25402006, 16082366 intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP2K4 MAP3K2 17906693,9162092,7997270,10713157, 25402006, 23023127, 21836163 innatedb,hprd,biogrid exp, pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP GP G YWHAB MAP3K2 15324660,24255178,26496610,17353931, 25402006 biogrid,mint,intact exp, pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G IKBKB MAP3K2 25402006 ortho, pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G CHUK MAP3K2 25402006 ortho, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SQSTM1 MAP3K2 25402006, 23023127 ortho, pred G GP G G G G G G GP G GP GP G G G GP G G G G GP GP GP GP GP G GP GP G PPP2CA MAP3K2 25402006 ortho, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TXN MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP G GP G GP G GP GP G GEMIN5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G P GP GP GP GP G GP GP G MAPK13 MAP3K2 25402006, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RAI14 MAP3K2 25402006 pred G GP GP G GP GP G GP GP G G G G GP G G G GP GP G P G G GP GP G PRR5L MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TPD52L1 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP G G ILK MAP3K2 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G SRPK1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G AKTIP MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 MAP3K2 25402006 pred P P P P P P P P P P P P P P P DBN1 MAP3K2 25402006 pred G G G G G GP G G GP G GP G G G G GP G G G GP GP G G G GP GP G EPHB1 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G DNAJB5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G WWOX MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K2 IRS2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G UBA52 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TUBA1A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HNRNPH1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PRKACG MAP3K2 23023127 pred P G G P P P P P P G G G P P P P P P GP MAP3K8 MAP3K2 25402006, 23023127 pred G GP G G P G GP GP GP GP G G G P P G GP GP P P GP G GP P G PFDN1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TUBB8 MAP3K2 25402006 pred P P P P P P P P P P P P LYN MAP3K2 25402006, 23023127 pred G G G G G GP G G GP G G G G G G GP GP G G G GP GP GP GP G GP G G TIMM50 MAP3K2 25402006 pred G GP G GP G GP GP G GP GP G G G GP GP G G P GP GP GP GP G GP GP G MYO1B MAP3K2 25402006 pred G G G G G GP G G GP G GP GP G G G GP GP G G G G GP GP G GP G GP GP G VBP1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TRIB2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G CCT7 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G LCK MAP3K2 25402006, 23023127 pred G G G G G G G G G G G G G G G G G PARK2 MAP3K2 23023127 pred GP G GP G GP GP G GP P G P GP G G P GP GP GP P GP G CCT2 MAP3K2 25402006 pred G GP G G G GP G GP GP G G GP G G G GP GP G G G GP GP G G GP G GP GP G RNF126 MAP3K2 25402006 pred G G G G G GP G G GP G GP G G G G GP GP G G GP GP G G GP G GP GP G VAV2 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP G GP GP G TEK MAP3K2 23023127 pred G GP G GP G GP GP G G G G G G GP GP G G G G G GP GP G GP P G VIM MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G G GP G G G G G G G G G G GP G SLC25A6 MAP3K2 25402006 pred G GP G G G GP G G G G GP GP G G G GP GP G G G G G GP G GP G GP GP G MATR3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G P GP GP GP GP G GP P MARS MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK10 MAP3K2 25402006, 23023127 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G RHOA MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G PDK1 MAP3K2 25402006 pred G GP G G G GP GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP TUBB2A MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP G G GP G GP G G MYO1E MAP3K2 25402006 pred G P G G GP G GP GP G GP GP G G G GP GP G G G GP GP G G GP G GP GP G MAP4K4 MAP3K2 21836163 pred G G G G G GP G GP G G GP GP G G G GP GP G G G G G G G GP G GP GP G BLK MAP3K2 23023127 pred G P P P P P G P P P P G P P IARS MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G G GP G G G GP G GP GP G G GP GP G NFATC4 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP GP GP G RPAP3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G P GP GP GP GP G GP GP G CHEK1 MAP3K2 25402006 pred G G G GP TUBA3E MAP3K2 25402006 pred P P P P P P P P P MAP4K1 MAP3K2 25402006, 23023127, 16082366 pred G G G G G G G G G G G G G G G G GP G G G G PIK3R4 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G MAP2K1 MAP3K2 25402006, 23023127, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PRKDC MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CDC37 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TMOD3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP P G MYH10 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G WEE1 MAP3K2 25402006 pred G GP G G P G G GP G G G G G GP P G G G GP G G G GP G GP GP G CALM1, CALM2, CALM3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SORBS3 MAP3K2 23023127 pred G G G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP G G MAPK4 MAP3K2 25402006, 23023127 pred P P P P P GP P P G P P P P P P P IQGAP1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G FLNA MAP3K2 25402006 pred G G G G G GP G G GP G GP GP G G G G GP G G G GP G G G G G GP GP G PRKAA1 MAP3K2 23023127 pred G GP G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP ITSN1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G MAP3K12 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G ROR2 MAP3K2 23023127 pred GP P P P P P GP P G P GP P P GP GP P G XAF1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G GP G GP G GP G GP GP G TUBA1C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G CDK7 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP P G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK11 MAP3K2 25402006, 16082366 pred G GP G G G GP G GP GP G GP GP G G G P GP G G G GP GP GP GP P G GP GP G CDK1 MAP3K2 23023127 pred G G G G GP P GP G G G GP P GP G GP GP ARRB2 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G CLTC MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G RGL3 MAP3K2 23023127 pred G GP G G G GP GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP P G SCRIB MAP3K2 25402006 pred G GP G G G G G GP GP G GP GP G G G GP G G G G GP GP GP G GP G GP GP G DAXX MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G UBE2I MAP3K2 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G TRIB3 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K9 MAP3K2 25402006, 23023127 pred GP G GP G GP G GP GP G G GP GP G G GP GP GP GP GP G GP GP G LATS1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PDCD6 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BAG5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PFDN6 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G HDAC5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FLNC MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G NBR1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DBNL MAP3K2 25402006, 23023127, 16082366 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G TP73 MAP3K2 23023127 pred G G G G G EEF1A2 MAP3K2 25402006 pred G G GP G GP G G P G G GP G G P GP G GP G GP G G AKT2 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G UBE2V1 MAP3K2 23023127 pred RPS16 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G PPP1R12A MAP3K2 25402006 pred G G G G G GP G GP GP G G G G G G GP GP G G G GP G G GP GP G GP GP G VAV3 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G USP44 MAP3K2 23023127 pred P P P P P P P P G G P P P P P P GP CAMKK2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G TSSK6 MAP3K2 23023127 pred G HSPA6 MAP3K2 25402006 pred G GP G G G P G GP GP GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MPRIP MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DDB1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CDC25B MAP3K2 25402006 pred G G G G G GP G GP GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G AKT1 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DNAJA1 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G PPP1CC MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PPP2R1B MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G NTRK3 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SYK MAP3K2 23023127 pred G G G G G GP G GP G GP G G G G GP GP G G G G G G GP G GP GP G UXT MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G GEM MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G RELA MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK8IP1 MAP3K2 25402006, 23023127 pred P G GP G P P G P P P GP G P P P P P P GP SLC25A5 MAP3K2 25402006 pred G GP G G G GP G G G G GP GP G G G GP GP G G G G G GP G GP G GP GP G ARHGEF6 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G G G G G GP G GP G G EPHA10 MAP3K2 23023127 pred P G GP P GP G P G G G P GP G P P G P P G GP GP ROS1 MAP3K2 23023127 pred G G G P GP P G GP G G G G G GP G G MAP3K2 MAP4K5 25402006, 23023127, 16082366 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G GP G G GP GP G HCK MAP3K2 23023127 pred G G G G G GP G G G G P GP G G G GP GP G G G GP GP GP GP GP G GP P G CCND1 MAP3K2 23023127 pred G GP G GP G G GP G GP GP G G G GP GP G G G G G GP G GP G GP P G UBXN2B MAP3K2 23023127 pred G GP G G G G G G GP G GP G G G G GP G G G G G GP G G GP G GP GP G MAP3K2 DUSP10 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G ATF2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G EIF2AK2 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G VCP MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CTNNB1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G DAB2IP MAP3K2 25402006 pred G G G GP G G G G G G G G G G GP G G G G GP G G G G G G G FGFR1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G ACVR2A MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CDK14 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G G GP G GP GP G PLK3 MAP3K2 23023127 pred G GP P G G P G P P G G G GP P G G G GP P GP G GP G GP P G AXIN1 MAP3K2 23023127 pred G GP G G GP G P GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G AURKA MAP3K2 23023127 pred G G P G G G G G G P G G G G G GP GNAI2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TUBA1B MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SMARCC2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CPVL MAP3K2 25402006 pred G G G G G G G GP G G GP G G G G G G G G G GP G G G G G G GP G PTPN3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP GP GP G ARAF MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBQLN1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K15 MAP3K2 25402006 pred P P P P P P P P P P P P P P MINK1 MAP3K2 23023127 pred G G G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G PARD6G MAP3K2 16082366 pred G G G G G G G G G G GP G G G G G G G G G G G GP G G G G GP G ARRB1 MAP3K2 25402006 pred G G G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G CCT5 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G RAF1 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K14 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PRKCI MAP3K2 23023127, 16082366 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP G G GP G GP GP G TUBA3C, TUBA3D MAP3K2 25402006 pred P P P P P P P P P ZEB2 MAP3K2 23023127 pred G G G G G GP G GP G G GP GP G G G G GP G G G G G G G G G G MAPK1 MAP3K2 23023127, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G USP14 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DNAJB4 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CAPZA1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SOCS1 MAP3K2 25402006 pred G GP P GP GP GP GP G G G GP P G G G GP P GP P GP G GP GP G PARD6B MAP3K2 16082366 pred P P P P GP G G G GP P G GP GP GP P GP GP GP G VRK3 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FES MAP3K2 23023127 pred G P G G P GP GP P GP G G P P GP P GP P G P P GNAI3 MAP3K2 25402006 pred G GP G G G GP G GP GP G G G G G G GP GP G G G G G G G GP G GP GP G PLCE1 MAP3K2 23023127 pred G P G GP G GP GP G GP P G G GP GP G G G P GP GP GP GP G GP P G PTPLAD1 MAP3K2 23023127, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G MAP4K2 MAP3K2 23023127 pred P P P P P P P P P P P P P P P MAP3K2 STRAP 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G EPHB2 MAP3K2 23023127 pred GP G G G GP G GP GP G GP P G GP GP G G G GP P GP GP GP P GP G NCK1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G DNAJC7 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G EGFR MAP3K2 23023127 pred G GP G GP G G GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G TNIK MAP3K2 23023127 pred GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G S100A7 MAP3K2 25402006 pred G G KRAS MAP3K2 23023127 pred G G G G G GP G G GP G GP G G G G GP GP G G G G GP GP GP GP G GP GP G TGFBR2 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CDK16 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MARK3 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G MAP3K2 SCIN 25402006 pred P G P G GP GP GP GP G GP GP SPTBN1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G KIT MAP3K2 23023127 pred G G G G G GP G G G G G G G G G GP G G G G G G G G G G G STAT3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PRKCZ MAP3K2 25402006, 16082366 pred G GP G GP G GP GP G GP GP G G G GP GP G G GP GP GP P GP G GP GP SCO2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G PTPN11 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G TUBB MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K2 TRAF6 25402006 pred G GP G G G G G GP GP G GP GP G G G GP G G G G GP GP GP G GP G GP GP G NLK MAP3K2 25402006 pred G GP G G G GP G G GP G G G G G G G GP G G G GP GP G G G G G GP G BIRC3 MAP3K2 25402006 pred G G G G G GP P GP G G G GP G G P G GP GP G GP GP RPS27A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CSNK1D MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G UBE2V2 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ALK MAP3K2 25402006 pred G GP G GP G GP GP G P G G G G GP GP G G G GP P GP GP GP GP GP G CCT8 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CCNB1 MAP3K2 23023127 pred G G G G G G GP G P G GP G G G G GP G P GP GP GP BAG2 MAP3K2 25402006 pred G GP G GP G GP GP G GP G G GP GP G G G GP GP GP GP GP GP G RUVBL1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G GP G GP GP G TFG MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G TUBB6 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G G GP GP G GP G GP GP G HIPK4 MAP3K2 23023127 pred G G G G G GP G GP GP G GP G G G G GP GP G G G GP G GP GP GP G GP GP G PFDN2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G NUAK1 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HSPA1L MAP3K2 25402006 pred G P G G G G G G G G P G G G G GP G GNA13 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FYN MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G G GP G G G G G G G G G G G G FRYL MAP3K2 25402006 pred G G G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G RET MAP3K2 23023127 pred GP G G G GP G G P G GP GP G G GP GP G G G GP GP GP GP P P GP G MYL12A MAP3K2 25402006 pred P P P P P P P PYGM MAP3K2 25402006 pred G G GP G G GP G P P G G G GP G G G GP GP G G GP G CDKN1C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DVL3 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HIPK3 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK8IP2 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DNAJA2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G APP MAP3K2 25402006 pred G GP G G G GP G G GP G G G G G G GP GP G G G GP GP G G GP G G GP G MTOR MAP3K2 25402006 pred G GP G G G GP G G G G G G G G G G GP G G G G GP G G G G GP G G UBE2B MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G LIMK1 MAP3K2 23023127 pred GP GP G P P G P P P GP G G P P P P P P CAPZB MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G BTK MAP3K2 23023127 pred G G G G G G G G G G G ELK1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G PRKCD MAP3K2 21836163 pred G GP G G G GP G GP GP GP P G G G GP GP G G GP GP GP P GP G GP GP G MAP3K19 MAP3K2 25402006 pred P P P P P P P P P P P P P P GP G PKN3 MAP3K2 25402006 pred G GP P GP G GP GP G G G GP P G G P P GP G GP G GP P G PPP2R1A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RAB5A MAP3K2 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K7 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G G GP G G G G GP G G G GP GP G G G G GP GP G TRIB1 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AIFM1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G MYL6 MAP3K2 25402006 pred G G G G G GP G GP GP G G G G G G G GP G G G GP G G G G G G G G TRAF2 MAP3K2 25402006 pred P P P P P P P P P P P P P G GP P CDC25A MAP3K2 25402006 pred G G P P P P P P P P P P P P GP VRK2 MAP3K2 25402006 pred G GP G G G G G GP GP G GP GP G G G GP G G G G GP GP GP GP GP G GP GP G UBL4B MAP3K2 23023127 pred P P P P P P P P P P P P P P SH3BP5 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G G GP G G G G G GP G GSTP1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G TUBB4B MAP3K2 25402006 pred G G G G G GP G G GP G G G G G G GP GP G G G GP GP GP G GP G GP GP G CCND2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G G G GP GP G GP G G EPHA1 MAP3K2 23023127 pred G GP G G P G P GP GP GP G G G GP P G GP GP GP P GP G GP GP G CAD MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G P GP G GP GP G CSNK2A1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RIPK2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G G GP G CCAR2 MAP3K2 25402006 pred P G GP P GP G GP P P GP G P P GP GP P P GP ACTN4 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK8IP3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G STK3 MAP3K2 23023127 pred G GP G G GP G GP GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G DNAJB1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP4K3 MAP3K2 23023127 pred G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G DNAJA4 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K10 MAP3K2 25402006, 23023127 pred P P P P P P P P P P P P P P P NCF4 MAP3K2 16082366 pred G G G G G G G G G G G G G NCF4 MAP3K2 16082366 pred G G G G G G G G G G G G G FLT4 MAP3K2 23023127 pred G G G G G G G G G G G G G G G PPP1CA MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G STRADA MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MYLK2 MAP3K2 25402006, 23023127 pred G G P P P P GP GP TUBB1 MAP3K2 25402006 pred G P G G P G GP P P P P G P P P P G P GP AKAP8L MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FASN MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G MYO5C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G TCP1 MAP3K2 25402006 pred P P P P P P P P P P P P P P P TYK2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MLST8 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G FER MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G ITK MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G FGFR3 MAP3K2 23023127 pred G P G GP GP G G GP G GP GP G G GP G GP G G GP RICTOR MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PARD6A MAP3K2 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G P GP GP GP GP G GP GP G SH3RF1 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MARK2 MAP3K2 25402006 pred P G G G GP GP GP G P P G GP GP G GP GP GP P P G GP P ITSN2 MAP3K2 23023127 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP GP G G GP G GP GP G PDPK2P MAP3K2 23023127 pred REL MAP3K2 25402006 pred G G G G G GP G G GP G GP G G G G GP GP G G G P GP GP G GP G GP GP G ERBB2 MAP3K2 25402006, 23023127 pred G G G G G G G G GP G GP G G G G GP G G G G GP GP G G GP G G G G PHGDH MAP3K2 25402006 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G PPP5C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TAOK2 MAP3K2 23023127 pred G GP G G G GP G G GP G G GP G G G GP GP G G G GP G G G GP G GP GP G MAP2K6 MAP3K2 25402006, 23023127, 21836163 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP G G DUSP19 MAP3K2 25402006 pred P P P P P P P G P P P P P OSBPL3 MAP3K2 25402006 pred G G G G GP G G GP G GP G G G G GP G G G GP G G G G P G RASGRF2 MAP3K2 16082366 pred G GP G G G GP G GP GP G GP P G G G GP GP G G G GP GP P GP GP G GP GP G DNAJB11 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DVL2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TESK1 MAP3K2 25402006 pred G G G G G GP G GP G G G GP G G G G GP G G G G G G G G G G G G FGFR2 MAP3K2 23023127 pred G GP G GP P GP G GP GP G G GP GP G G G GP G G P GP GP GP G PRR5 MAP3K2 25402006 pred G G G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SEC16A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RIPK1 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G TTK MAP3K2 23023127 pred P G G P P GP P P GP P P P P P GP GP GP FGD4 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G UBE2U MAP3K2 23023127 pred P P P P P P P P P P P P P P GP MYO1A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G GP GP G G G GP GP GP GP GP GP GP G STRADB MAP3K2 25402006, 23023127 pred G G G G G GP G GP GP G GP GP G G G G GP G G G G G G GP G G G GP G ABL2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DYRK1A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G TNK2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G LGALS7, LGALS7B MAP3K2 25402006 pred GRB2 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DUSP22 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HSPA5 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CBL MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G G G G G G G G GP G TAOK1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G BMPR2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G GP G GP GP G GP GP G CCT6A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MYO6 MAP3K2 25402006 pred G GP G GP G G GP G GP GP G G G GP GP G G G GP GP GP P GP G GP GP PDGFRB MAP3K2 23023127 pred G G G G G GP G G G G GP G G G G G GP G G G GP GP G G G G GP GP G MAPKAPK3 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PDRG1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G PKN1 MAP3K2 23023127, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DNAJB13 MAP3K2 25402006 pred G G G G G G G GP GP G GP G G G G GP G G G G G G G GP GP G G GP G MAP2K2 MAP3K2 25402006, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G IQGAP2 MAP3K2 25402006 pred G GP G G P G GP GP GP GP G G G GP P G G G GP GP GP GP G GP GP G UACA MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G TUBB2B MAP3K2 25402006 pred P G GP G GP G GP P G GP GP G G GP GP GP GP P G MCC MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SUMO2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RPS27 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PAK2 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP G GP GP GP G GP G G UBE2N MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MYO1G MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP GP G MYO1C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G TUBB4A MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G GP GP G G G GP P GP GP GP G GP GP G PTK2B MAP3K2 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G P GP G G GP G GP GP G MAP3K2 MYO5A 25402006 pred G G G G G GP G G GP G GP G G G GP GP G G G GP GP GP G GP G GP GP G FLT1 MAP3K2 23023127 pred G G G GP G GP GP G G G G G G G GP G G G GP G G GP G G G G G PRKCE MAP3K2 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP G GP G GP G GP GP G UBE2D1 MAP3K2 23023127 pred G G G G G GP G G GP G GP GP G G G G GP G G G GP GP G GP G G GP GP G TAOK3 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CFL2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G TSC1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G GSTM1 MAP3K2 25402006 pred G GP G G G G G G G G G GP G G G G G G G G G G G G G G G GP G IGF1R MAP3K2 23023127 pred G GP G G G G G GP GP G GP GP G G G GP G G G G GP GP GP G GP G GP GP G MLK4 MAP3K2 25402006, 23023127 pred GP G G G GP G GP G GP GP G G G GP GP G G GP G GP GP GP GP G GAB2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CDC25C MAP3K2 25402006 pred P G G P P GP P GP P P P P P GP P GP G TUBB3 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G ZAK MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G BUB1B MAP3K2 23023127 pred P G G P GP GP P P G GP P G GP P P P GP GP GP G DNAJA3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PDPK1 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G DLG1 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G PI4KB MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RUVBL2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G UBE2S MAP3K2 23023127 pred G G G G G G G G GP G G G G G G G G G G G G G G G GP G GAPDH MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PLK2 MAP3K2 23023127 pred G GP G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK15 MAP3K2 25402006, 23023127 pred G GP G G G GP GP GP G GP GP G GP GP G G GP P GP GP GP GP GP G SEPT4 MAP3K2 25402006 pred G GP G G G GP G G G G G G G G G G GP G G G G G G G G G GSPT1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CASP7 MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G RPTOR MAP3K2 25402006 pred G GP G GP G P P G P GP G G P GP G GP GP GP GP P G P GP G CORO1C MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K6 MAP3K2 25402006, 23023127, 16082366 pred G GP P G GP GP GP P G G G GP P G G P GP GP GP GP G GP P G UBE2G2 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP G G GP G GP GP G CCNG1 MAP3K2 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G MATK MAP3K2 23023127 pred P G G G GP P P P GP G G GP GP P P P P P G P P CAPNS1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G URI1 MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K11 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G APAF1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G DUSP1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G INSR MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAP3K2 STK24 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PAK1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK12 MAP3K2 25402006, 16082366 pred G GP G G G GP G GP GP G GP G G GP GP G G G P G G GP GP G GP GP G JAK2 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP P G G G P GP G P G GP G GP G GP GP GNB2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G G GP G GP G GP GP G PRKCG MAP3K2 23023127 pred G G G G G GP G G G G G G G GP G G G G G G G G CASP9 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HSPA9 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PFDN4 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP G GP GP G GP GP G PRKCB MAP3K2 23023127, 21836163 pred G GP G G G GP G G GP G GP G G G G G GP G G G G GP GP G G G GP GP G MAP3K2 MAP3K4 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G SNRNP200 MAP3K2 25402006 pred G G G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G ABL1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PTPN13 MAP3K2 25402006 pred G GP G GP G G GP G GP G G G GP GP G G G P GP GP GP G GP GP G HSPA2 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CFLAR MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MYO1D MAP3K2 25402006 pred G GP GP G P GP G GP GP G G G GP GP G G G GP G G GP G GP P G LIMA1 MAP3K2 25402006 pred G GP G G G G G G GP G GP G G G G GP G G G G GP GP GP GP GP G GP GP G CDC42 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G SKAP1 MAP3K2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBL4A MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP P G PIM2 MAP3K2 23023127 pred G G G G G GP G GP GP G G G G G G GP GP G G G GP GP G G GP G GP GP G LATS2 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G BRAF MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G P GP G G G GP GP GP GP P G GP GP G PKMYT1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP G G G GP GP G G G GP GP G GP GP G GP GP G MAP3K1 MAP3K2 25402006, 23023127, 21836163 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G GNB1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G G GP G GP G GP GP G SIRT1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G RB1CC1 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G RPS27L MAP3K2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CCT3 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK9 MAP3K2 25402006, 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G PFKL MAP3K2 25402006 pred G G G G G GP G G GP G GP GP G G G GP GP G G G GP G GP G GP G GP GP G IKBKE MAP3K2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RALGPS2 MAP3K2 25402006 pred G GP G G P G P GP GP GP G G GP P G GP P P GP G GP GP HSPA8 MAP3K2 25402006 pred P P P P P P P P P P P P DUSP4 MAP3K2 25402006 pred G G G G G G G G G G G G G G MAPK3 MAP3K2 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G JAK1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CCT4 MAP3K2 25402006 pred G GP G G G GP G G GP G GP G G G G G GP G G G GP G G G G G GP GP G ACTG1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G BCL2L11 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G CCND3 MAP3K2 23023127 pred G GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G NEK6 MAP3K2 23023127 pred G G G G G GP G GP G G GP G G G G GP GP G G G GP GP GP GP G GP GP G STK25 MAP3K2 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP G G G GP G GP GP G TUBE1 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G STK11 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G NUDC MAP3K2 25402006 pred G GP G G G GP G G GP G GP GP G G G GP GP G G G GP GP GP G GP G GP GP G LAMTOR3 MAP3K2 16082366 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP GP GP G GP G GP GP G MAPK6 MAP3K2 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G MAPK14 MAP3K2 25402006, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G MARK1 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP P G G G GP GP G G G GP GP GP GP GP G GP GP G BRCA1 MAP3K2 25402006 pred P G G P P P P P GP P P P P P P P GP MAP3K13 MAP3K2 25402006, 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G PRKCA MAP3K2 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G BIRC7 MAP3K2 25402006, 23023127, 16082366 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP P GP GP GP G GP GP G UBE2C MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G HIPK2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G UBE2E1 MAP3K2 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G EPHA8 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP G GP GP GP G GP GP G LIMK2 MAP3K2 23023127 pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G GP GP GP GP GP G GP GP G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B STUB1 MAP3K2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,20588253 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) MINT_47070|MINT_47503|UniProt_108052|UniProt_108051|UniProt_108050|UniProt_108049|UniProt_109734|UniProt_108048|MINT_79377|UniProt_109735|MINT_79361|UniProt_109733|MINT_79360|UniProt_109736|MINT_79359|MINT_79353|BIOGRID_162510|BIOGRID_162511|MINT_47496|MINT_79357|MINT_47495|MINT_79358|MINT_79355|MINT_47497|BIOGRID_162515|MINT_79356|MINT_47491|MINT_47492|MINT_47493|MINT_47494|MINT_47490|MINT_78865 prey|bait|bait|bait|bait|prey|bait|prey|bait|bait|bait|prey|bait|prey|bait|prey|prey|prey|bait|bait|bait|prey|prey|bait|bait|bait|prey|bait|bait|prey|prey|prey bait|prey|prey|prey|prey|bait|prey|bait|prey|prey|prey|bait|prey|bait|prey|bait|bait|bait|prey|prey|prey|bait|bait|prey|prey|prey|bait|prey|prey|bait|bait|bait WNK1 MAP3K2 MI:0493(in vivo) 14681216 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25749 - - MAP2K5 MAP3K2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0397(two hybrid array)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11073940,19903815,21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid) BIOGRID_99147|HPRD_20155|BIOGRID_99146|BIOGRID_146908|UniProt_117639|BIOGRID_146911|BIOGRID_288033 bait|-|prey|bait|unspecified role|prey|bait prey|-|bait|prey|unspecified role|bait|prey PIBF1 MAP3K2 MI:0018(two hybrid) 20936779 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_126989 prey bait SMURF1 MAP3K2 MI:0493(in vivo)|MI:0004(affinity chromatography technology) 15820682,19318350 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_32311|BIOGRID_201768 -|prey -|bait XIAP MAP3K2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18761086 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_116466|BIOGRID_116467 prey|bait bait|prey HSP90AA1 MAP3K2 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255347 bait prey MAP3K3 MAP3K2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 14743216 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact) MINT_53895|MINT_87509|UniProt_74936 bait|bait|bait prey|prey|prey MAP3K5 MAP3K2 MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0493(in vivo) 12912994 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|- MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) MINT_48690|MINT_78119|MINT_48689|MINT_78120|HPRD_10855 prey|prey|prey|prey|- bait|bait|bait|bait|- MAP2K3 MAP3K2 MI:0415(enzymatic study) 9162092 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_216267 prey bait MAP3K2 IKBKG MI:0089(protein array)|MI:0096(pull down) 20098747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_105621|BIOGRID_123916 null|prey prey|bait MAP2K4 MAP3K2 MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 10713157,17906693,7997270,9162092 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_217129|HPRD_8965|BIOGRID_114699|BIOGRID_216268 prey|-|prey|prey bait|-|bait|bait YWHAZ MAP3K2 MI:0493(in vivo) 9452471 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_8857 - - NFKBIA MAP3K2 MI:0493(in vivo) 10085062 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24831 - - UBC MAP3K2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10,20588253,21139048,21890473,21906983,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|(biogrid)|(biogrid)|(biogrid) BIOGRID_269045|BIOGRID_168426|MINT_79363|BIOGRID_162513|MINT_47499|UniProt_108053|BIOGRID_223333|BIOGRID_176018|BIOGRID_177806 bait|bait|prey|prey|prey|prey|bait|bait|bait prey|prey|bait|bait|bait|bait|prey|prey|prey MAP2K7 MAP3K2 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10713157,9372971 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_114705|HPRD_11885|BIOGRID_114698 prey|-|prey bait|-|bait STK38 MAP3K2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17906693 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_217050|BIOGRID_217049 prey|bait bait|prey PKN2 MAP3K2 MI:0493(in vivo) 10818102 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_11046 - - YWHAE MAP3K2 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 17979178,9452471 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0403(colocalization) (biogrid)|(biogrid)|(intact)|MI:0468(hprd)|(intact) BIOGRID_100728|BIOGRID_256864|UniProt_135326|HPRD_13483|UniProt_135331 bait|bait|bait|-|unspecified role prey|prey|prey|-|unspecified role HSP90AB1 MAP3K2 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_124908 prey bait YWHAG MAP3K2 MI:0004(affinity chromatography technology)|MI:0019(coimmunoprecipitation)|MI:0493(in vivo)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation) 15324660 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact) BIOGRID_150240|MINT_58509|HPRD_13708|MINT_55686|UniProt_79427 bait|bait|-|bait|bait prey|prey|-|prey|prey NEDD4L MAP3K2 MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_162416 bait prey SH2D2A MAP3K2 MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 11073940,12640115 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_99149|HPRD_31122|BIOGRID_99150 prey|-|prey bait|-|bait SFN MAP3K2 MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification) 15778465 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0471(mint) BIOGRID_84965|MINT_84487|UniProt_81319|MINT_52024 bait|bait|bait|bait prey|prey|prey|prey MAPK8 MAP3K2 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10713157 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|-|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_114706|HPRD_8491|BIOGRID_114703 prey|-|prey bait|-|bait YWHAB MAP3K2 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 15324660,17353931,24255178 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact)|MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|(intact) UniProt_176935|BIOGRID_150114|UniProt_150306|MINT_55788|BIOGRID_293509|UniProt_79501|MINT_58619|UniProt_131089 bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey NEDD4 MAP3K2 MI:0415(enzymatic study)|MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_164750|BIOGRID_148281 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAQ MAP3K2 26496610,26496610 0007,0004 HT YWHAB MAP3K2 26496610,17353931,15324660,24255178,15324660 0007,0006,0004,0007,0019 HT SFN MAP3K2 26496610,15778465,15778465,26496610 0007,0676,0004,0004 HT,LC YWHAG MAP3K2 15324660,26496610,26496610,15324660 0004,0004,0007,0019 HT YWHAE MAP3K2 26496610,9452471,9452471,9452471 0007,0428,0096,0019 HT,LC YWHAZ MAP3K2 26496610,26496610 0007,0004 HT XIAP MAP3K2 24975362,24975362,24975362,18761086,18761086,24975362 0096,0415,0004,0004,0415,0006 LC MAP2K5 MAP3K2 11073940,24975362,24975362,24975362,19903815,11073940 0018,0096,0415,0004,0004,0004 LC STX3 MAP3K2 26496610 0007 HT STX3A MAP3K2 26496610 0004 HT TRAF7 MAP3K2 26496610,26496610 0007,0004 HT MAP3K3 MAP3K2 26496610,26496610,24975362,14743216,14743216 0004,0007,0096,0007,0676 HT,LC MAP3K2 MAP3K2 17906693,24975362,17906693 0004,0096,0415 LC MAP3K2 HEL2 17979178,9452471,26496610 0004,0096,0004 LC,HT MAP3K2 HEL-S-1 15324660,24255178,26496610 0004,0004,0004 HT YWHAQ MAP3K2 26496610,26496610 0007,0004 HT YWHAB MAP3K2 26496610,17353931,15324660,24255178,15324660 0007,0006,0004,0007,0019 HT SFN MAP3K2 26496610,26496610 0007,0004 HT YWHAG MAP3K2 15324660,26496610,26496610,15324660 0004,0004,0007,0019 HT YWHAE MAP3K2 26496610 0007 HT YWHAZ MAP3K2 26496610,26496610 0007,0004 HT STX3 MAP3K2 26496610 0007 HT STX3A MAP3K2 26496610 0004 HT TRAF7 MAP3K2 26496610,26496610 0007,0004 HT MAP3K3 MAP3K2 26496610,26496610,14743216,14743216 0004,0007,0007,0676 HT MAP3K2 HEL2 26496610 0004 HT MAP3K2 HEL-S-1 15324660,24255178,26496610 0004,0004,0004 HT SFN MAP3K2 15778465,15778465 0676,0004 LC YWHAE MAP3K2 9452471,9452471,9452471 0428,0096,0019 LC XIAP MAP3K2 24975362,24975362,24975362,18761086,18761086,24975362 0096,0415,0004,0004,0415,0006 LC MAP2K5 MAP3K2 11073940,24975362,24975362,24975362,19903815,11073940 0018,0096,0415,0004,0004,0004 LC MAP3K3 MAP3K2 24975362 0096 LC MAP3K2 MAP3K2 17906693,24975362,17906693 0004,0096,0415 LC MAP3K2 HEL2 17979178,9452471 0004,0096 LC B7Z2P9 MAP3K2 19953087 0415 HT MAP2K7 MAP3K2 12659851,10713157,10713157,24975362,10713157 0045,0004,0401,0415,0059 LC USP2 MAP3K2 24975362 0415 LC STAMBP MAP3K2 24975362 0415 LC HSP90AB1 MAP3K2 22939624 0729 HT PKM MAP3K2 24606918 0424 LC YWHAB MAP3K2 15324660,15324660 0004,0019 LC CTNNB1 MAP3K2 26884171,26884171,26884171 0096,0004,0415 LC MAPK8 MAP3K2 10713157,10713157 0004,0401 LC MAP2K4 MAP3K2 10713157,10713157,9162092,17906693 0004,0059,0415,0415 LC MAP2K3 MAP3K2 9162092 0415 LC NEDD4 MAP3K2 19953087,19953087 0415,0096 HT YWHAG MAP3K2 15324660,15324660 0004,0019 LC YWHAE MAP3K2 9452471,9452471,9452471 0428,0096,0019 LC XIAP MAP3K2 24975362,24975362,24975362,18761086,18761086,24975362 0096,0415,0004,0004,0415,0006 LC MAP2K5 MAP3K2 11073940,12659851,24975362,24975362,21988832,PDB_2NPT,24975362,21988832,11073940 0018,0045,0096,0415,0397,0114,0004,0018,0004 LC,HT BIRC2 MAP3K2 24975362 0415 LC PKN2 MAP3K2 12640115,10818102 0018,0018 LC PIBF1 MAP3K2 20936779 0018 HT NEDD4L MAP3K2 19953087 0415 HT MAP3K5 MAP3K2 12912994,12912994 0096,0019 LC SMURF1 MAP3K2 20804422,15820682 0415,0018 LC SH2D2A MAP3K2 11073940,12640115,11073940 0018,0018,0004 LC STUB1 MAP3K2 20588253,20588253,20588253,20588253,20588253 0096,0007,0004,0006,0415 LC MAP3K2 MAP3K2 9162092,12659851,17906693,11343802,15001576,17906693 0415,0045,0004,0423,0415,0415 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y2U5 P61981 MAP3K2 YWHAG 0.416 15324660,26496610 Q9Y2U5 O15169 MAP3K2 AXIN1 0.21 26884171 Q9Y2U5 Q04917 MAP3K2 YWHAH 0.126 17979178 Q9Y2U5 Q9HCE7 MAP3K2 SMURF1 0.354 20804422,19318350 Q9Y2U5 Q9WUD1 MAP3K2 STUB1 0.523 20588253 Q9Y2U5 P07900 MAP3K2 HSP90AA1 0.126 22939624 Q9Y6K9 Q9Y2U5 IKBKG MAP3K2 0.183 20098747 Q9Y2U5 Q96QF0 MAP3K2 RAB3IP 0.126 unassigned1312 Q9Y2U5 Q8WXW3 MAP3K2 PIBF1 0.183 20936779 Q9Y2U5 P46734 MAP3K2 MAP2K3 0.309 9162092 Q9Y2U5 P47809 MAP3K2 MAP2K4 0.309 20588253 Q9Y2U5 P14618 MAP3K2 PKM 0.033 24606918 Q9Y2U5 P0CG48 MAP3K2 UBC 0.21 20588253 Q9Y2U5 Q9Y297 MAP3K2 BTRC 0.21 26884171 Q9Y2U5 P27348 MAP3K2 YWHAQ 0.126 26496610 Q9Y2U5 J3QRB6 MAP3K2 MAP3K3 {ECO:0000313|ENSEMBL:ENSP00000464130} 0.126 26496610 Q9Y2U5 Q9Y2T1 MAP3K2 AXIN2 0.21 26884171 Q9Y3M2 Q9Y2U5 CBY1 MAP3K2 0.126 unassigned1312 Q9Y2U5 O75604 MAP3K2 USP2 0.309 24975362 Q9Y2U5 P08238 MAP3K2 HSP90AB1 0.126 22939624 Q9Y2U5 O95630 MAP3K2 STAMBP 0.309 24975362 Q9Y2U5 P31947 MAP3K2 SFN 0.416 26496610,15778465 Q9Y2U5 P45983 MAP3K2 MAPK8 0.309 10713157 Q9Y2U5 P63104 MAP3K2 YWHAZ 0.236 26496610 Q9Y2U5 Q13277 MAP3K2 STX3 0.236 26496610 Q9Y2U5 Q6Q0C0 MAP3K2 TRAF7 0.236 26496610 Q9Y2U5 Q9NP31 MAP3K2 SH2D2A 0.454 11073940 Q9Y2U5 P46934 MAP3K2 NEDD4 0.332 19953087 Q9Y2U5 P62258 MAP3K2 YWHAE 0.681 17979178,9452471,26496610 Q9Y2U5 Q9UNE7 MAP3K2 STUB1 0.853 20588253 Q9Y2U5 P98170 MAP3K2 XIAP 0.888 24975362,18761086 Q9Y2U5 O14733 MAP3K2 MAP2K7 0.523 24975362,10713157 Q9Y2U5 P45985 MAP3K2 MAP2K4 0.623 10713157,17906693,9162092 Q9Y2U5 Q99759 MAP3K2 MAP3K3 0.472 14743216,24975362,26496610 Q9Y2U5 P31946 MAP3K2 YWHAB 0.659 15324660,24255178,17353931,26496610 Q9Y2U5 Q13163 MAP3K2 MAP2K5 0.937 24975362,11073940,19903815,21988832 Q9Y2U5 Q9Y2U5 MAP3K2 MAP3K2 0.848 24975362,9162092,15001576,17906693 Q9Y2U5 P35222 MAP3K2 CTNNB1 0.702 26884171 Q9Y2U5 Q96PU5 MAP3K2 NEDD4L 0.183 19953087 Q9Y2U5 P49841 MAP3K2 GSK3B 0.21 26884171 Q9Y2U5 Q15208 MAP3K2 STK38 0.376 17906693 Q9Y2U5 Q13164 MAP3K2 MAPK7 0.21 24975362 Q9Y2U5 Q13490 MAP3K2 BIRC2 0.309 24975362

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MAP2K7 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database USP2 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database STAMBP MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database UBC MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database PKM MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAQ MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAB MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database SFN MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAPK8 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAP2K4 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAP2K3 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAG MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAE MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database XIAP MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAH MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAP2K5 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAPK7 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database STX3 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database BIRC2 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database STK38 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database PKN2 MAP3K2 MI:0362 inference MI:0461 interaction database TRAF7 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database PIBF1 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database BIRC8 MAP3K2 MI:0362 inference MI:0461 interaction database NEDD4L MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K3 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database SMYD3 MAP3K2 MI:0362 inference MI:0461 interaction database SMURF1 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database SH2D2A MAP3K2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database STUB1 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K2 IKBKG MI:0045 experimental interaction detection MI:0461 interaction database