Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 4 141816657 rs767761 C A rs767761 2.99E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 4 141891566 rs1425431 T C rs1425431 2.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_drug 4 141891566 rs1425431 T C rs1425431 2.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_drug 4 141891566 rs1425431 T C rs1425431 8.05E-05 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_drug 4 141891993 rs10519574 C A rs10519574 2.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141891993 rs10519574 C A rs10519574 2.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141891993 rs10519574 C A rs10519574 2.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141891993 rs10519574 C A rs10519574 7.65E-05 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141895912 rs17343501 C A rs17343501 5.02E-04 CHOLESTEROL ABCG8 PROTEIN, HUMAN Gallstones HPOID:0001081 DOID:11151 A intron GWASdb_drug 4 141931721 rs13132043 T C rs13132043 1.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141931721 rs13132043 T C rs13132043 1.00E-04 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141931721 rs13132043 T C rs13132043 2.26E-05 TOPIRAMATE|FRUCTOSE ANTICONVULSANTS Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_drug 4 141993345 rs4482847 A C rs4482847 3.67E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_drug 4 141996416 rs3851432 C T rs3851432 2.82E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 4 142009987 rs17006859 A G rs17006859 3.82E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 4 141815089 rs10034843 A C rs10034843 6.80E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 A intron GWASdb_trait 4 141816657 rs767761 C A rs767761 2.99E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 4 141825374 rs1364886 C T rs1364886 1.04E-05 Odorant perception HPOID:0000366 DOID:0050155 T intron GWASdb_trait 4 141826780 rs1030356 G A rs1030356 3.61E-05 Lung function (forced expiratory volume in 1 second) HPOID:0002088 DOID:850 G intron GWASdb_trait 4 141826780 rs1030356 G A rs1030356 5.77E-05 ldl cholesterol HPOID:0010979 DOID:1936|DOID:3393 G intron GWASdb_trait 4 141830252 rs961402 A C rs961402 1.01E-04 Parkinson's disease HPOID:0001300 DOID:14330 A intron GWASdb_trait 4 141833535 rs1834382 C T rs1834382 3.11E-06 Cholesterol HPOID:0003107 DOID:2349|DOID:3393|DOID:3146 T intron GWASdb_trait 4 141833535 rs1834382 C T rs1834382 4.91E-07 ldl cholesterol HPOID:0010979 DOID:1936|DOID:3393 T intron GWASdb_trait 4 141833535 rs1834382 C T rs1834382 1.48E-05 Cholesterol HPOID:0003107 DOID:2349|DOID:3393|DOID:3146 T intron GWASdb_trait 4 141833760 rs1425442 G C rs1425442 2.51E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 4 141834589 rs17338560 C T rs17338560 3.84E-04 Lung function (forced expiratory volume in 1 second to forced vital capacity ratio) HPOID:0002088 DOID:850 C intron GWASdb_trait 4 141836576 rs6537018 G A rs6537018 2.09E-04 Lung function (forced expiratory volume in 1 second to forced vital capacity ratio) HPOID:0002088 DOID:850 G intron GWASdb_trait 4 141845689 rs11930778 T C rs11930778 4.15E-04 Obesity (extreme) HPOID:0001513 DOID:9970 C,T intron GWASdb_trait 4 141848200 rs17339131 T C rs17339131 4.03E-04 Obesity (extreme) HPOID:0001513 DOID:9970 T intron GWASdb_trait 4 141848258 rs12642167 A G rs12642167 1.73E-04 Lung function (forced expiratory volume in 1 second to forced vital capacity ratio) HPOID:0002088 DOID:850 G intron GWASdb_trait 4 141851355 rs13118519 C T rs13118519 8.21E-04 Acne (severe) HPOID:0001061 DOID:6543 T intron GWASdb_trait 4 141851779 rs17423804 C T rs17423804 4.96E-04 Obesity (extreme) HPOID:0001513 DOID:9970 T,C intron GWASdb_trait 4 141852682 rs6537022 G A rs6537022 5.21E-05 Obesity (extreme) HPOID:0001513 DOID:9970 G intron GWASdb_trait 4 141853440 rs7658326 A G rs7658326 1.80E-05 Obesity (extreme) HPOID:0001513 DOID:9970 A intron GWASdb_trait 4 141854382 rs17006670 T C rs17006670 5.13E-05 Obesity (extreme) HPOID:0001513 DOID:9970 T intron GWASdb_trait 4 141868515 rs1001487 T C rs1001487 1.06E-04 Height HPOID:0000002 NA A intron GWASdb_trait 4 141875683 rs2321689 C T rs2321689 1.51E-04 Blood pressure HPOID:0011025 DOID:10763 C intron GWASdb_trait 4 141881246 rs1425443 C T rs1425443 6.12E-05 C-Reactive Protein HPOID:0010876 DOID:14221|DOID:9352|DOID:10763|DOID:5844 T intron GWASdb_trait 4 141891566 rs1425431 T C rs1425431 2.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_trait 4 141891566 rs1425431 T C rs1425431 2.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_trait 4 141891566 rs1425431 T C rs1425431 8.05E-05 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 T intron GWASdb_trait 4 141891993 rs10519574 C A rs10519574 2.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141891993 rs10519574 C A rs10519574 2.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141891993 rs10519574 C A rs10519574 2.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141891993 rs10519574 C A rs10519574 7.65E-05 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141895912 rs17343501 C A rs17343501 5.02E-04 Gallstones HPOID:0001081 DOID:11151 A intron GWASdb_trait 4 141896970 rs1364881 C T rs1364881 1.40E-05 Urinary metabolites HPOID:0000079 DOID:557 C intron GWASdb_trait 4 141920037 rs11726692 A G rs11726692 1.10E-05 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 4 141931721 rs13132043 T C rs13132043 1.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141931721 rs13132043 T C rs13132043 1.00E-04 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141931721 rs13132043 T C rs13132043 2.26E-05 Cognitive impairment induced by topiramate HPOID:0100543 DOID:1561 C intron GWASdb_trait 4 141933097 rs7687054 T C rs7687054 4.42E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 4 141957064 rs11100699 A C rs11100699 7.77E-04 Alzheimer's disease HPOID:0002511 DOID:10652 A intron GWASdb_trait 4 141965158 rs9991795 C T rs9991795 2.67E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 4 141993345 rs4482847 A C rs4482847 3.67E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_trait 4 141996416 rs3851432 C T rs3851432 2.82E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 4 142005573 rs10007052 C A rs10007052 1.00E-07 Chronic obstructive pulmonary disease-related biomarkers HPOID:0006510 DOID:3083 A intron GWASdb_trait 4 142009987 rs17006859 A G rs17006859 3.82E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 4 142016173 rs10454797 G A rs10454797 6.05E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 4 142046828 rs1027816 T C rs1027816 1.80E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait