PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE2W RNF150 19690564 biogrid,intact exp GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G UBE2Z RNF150 19690564 biogrid,intact exp GP GP G G G GP G G GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G MOV10 RNF150 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G UBE2L6 RNF150 19690564 biogrid,intact exp GP GP G G G GP G G GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G UBE2U RNF150 19690564 biogrid,intact exp P P P P P P P P P P P P P P P P P P GP ELAVL1 RNF150 19322201 biogrid exp GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP G GP GP G UBE2D1 RNF150 19690564, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP P GP GP G G GP G GP G P GP G G G GP GP GP G UBE2E3 RNF150 19690564, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G GP G GP GP G G G P G G G GP G GP GP G UBE2D2 RNF150 19690564, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP P GP GP G G GP G GP G P GP G G G GP GP GP G UBE2D3 RNF150 19690564, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP P GP GP G G GP G GP G P GP G G G GP GP GP G RNF150 UBE2D4 19690564, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP P GP GP G G GP G GP G P GP G G G GP GP GP G UBE2E1 RNF150 19690564, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP G GP G GP GP G G G P G G G GP G GP GP G UBE2NL RNF150 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G MTX2 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G RNFT2 RNF150 23023127 pred P P G GP G P G P P P GP P G P P P P RNF150 ANKRD6 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G SLC25A23 RNF150 23023127 pred G G G GP G GP GP G GP P GP G G GP GP G GP G G GP G GP G GP GP G CUL4A RNF150 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AKTIP RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G MTMR4 RNF150 23023127 pred GP G G G G GP G GP GP G GP P GP G G GP GP G GP G G GP G GP G GP G G BMI1 RNF150 23023127 pred P P P P P P P P P P P P P P P P P P P ANKRD34A RNF150 23023127 pred G G G G G G G UBE2R2 RNF150 23023127 pred G G G G G G G G G G G G GP G G G G G G G G G G GP GP G G ASB13 RNF150 23023127 pred GP G G G G GP G GP GP G GP GP GP G GP GP G GP G P GP GP G GP GP GP GP G PTCD3 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G UBE2N RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G UBE2K RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G RNF175 RNF150 23023127 pred GP P G G G GP G GP GP G G P GP GP G P GP GP GP P GP CLIP3 RNF150 23023127 pred GP GP G GP G GP GP G GP G GP G GP GP G GP G P G P GP GP GP GP G MYCBP2 RNF150 23023127 pred G GP G G G GP G GP GP G G GP GP G GP GP G GP G GP G G GP G G GP G FCHSD2 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP G G GP GP G GP G P GP P G GP GP GP G G RNF150 STUB1 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G CALN1 RNF150 23023127 pred P GP G GP P P G P P G P GP P P P P P P REPS2 RNF150 23023127 pred G G G G G GP G GP G GP P GP GP GP GP G GP G P GP G GP P GP P RNF41 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P G G GP GP P G P G P G GP GP GP P UNC45B RNF150 23023127 pred GP P P G G P P P UBE2L3 RNF150 23023127 pred GP G G G G GP G GP GP G GP G G G GP GP G GP G G GP G GP G GP GP G RNF165 RNF150 23023127 pred P P G GP P P G P P P P P GP P G P GP P G P GP P P ANKRD33B RNF150 23023127 pred GP P G G G GP G GP GP GP P P GP P GP P G P GP P G P GP GP P G PRICKLE2 RNF150 23023127 pred GP G G G G GP G G GP G GP GP GP G GP GP G G G P GP G G GP G GP GP G ANKRD39 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP GP GP G GP G P GP GP G GP G GP GP G RNF150 UNC13A 23023127 pred P P G GP G P G P P GP P G P P P P P TNNC2 RNF150 23023127 pred G GP G G G G P GP G P GP G G G G G G G G P GP UBE2E2 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G DGKZ RNF150 23023127 pred G G G G G GP G GP G G G G GP G G GP G GP G G GP G G G GP GP G TRIM37 RNF150 23023127 pred GP GP G G G GP G G GP G GP GP G G GP GP G GP G P GP GP G GP G GP GP G UBQLN2 RNF150 23023127 pred GP GP G G G GP G GP GP G GP P GP GP G GP GP G GP G P GP GP G GP GP GP GP G CUL2 RNF150 23023127 pred GP GP G G G GP G G GP G GP P GP GP G G GP G GP G P GP GP G G G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9ULK6 A0A024RA90 two hybrid 19690564 direct interaction X 2 Q9ULK6 A0A024R2K3 two hybrid 19690564 direct interaction X 2 Q9ULK6 two hybrid 19690564 direct interaction X 2 Q9ULK6 Q9H832 two hybrid 19690564 direct interaction X 2 Q969T4 Q9ULK6 two hybrid 19690564 direct interaction X 2 Q9ULK6 A0A087WW00 two hybrid 19690564 direct interaction X 2 Q9ULK6 P62837 two hybrid 19690564 direct interaction X 2 Q9ULK6 P61077-3 two hybrid 19690564 direct interaction X 2 Q9ULK6 O14933-2 two hybrid 19690564 direct interaction X 2 Q9ULK6 Q96FI0 two hybrid 19690564 direct interaction X 2 Q9ULK6 A0A024RDH2 two hybrid array 19690564 physical association X 2 Q9ULK6 A0A024RA90 two hybrid array 19690564 physical association X 2 Q9ULK6 A0A024R2K3 two hybrid array 19690564 physical association X 2 Q9ULK6 Q9H832 two hybrid array 19690564 physical association X 2 A0A024QZJ2 Q9ULK6 two hybrid array 19690564 physical association X 2 Q969T4 Q9ULK6 two hybrid array 19690564 physical association X 2 Q9ULK6 Q5VVX9 two hybrid array 19690564 physical association X 2 Q9ULK6 Q96B02 two hybrid array 19690564 physical association X 2 Q9ULK6 P62837 two hybrid array 19690564 physical association X 2 O14933 Q9ULK6 two hybrid array 19690564 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RNF150 UBE2D4 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123524|UniProt_102514 prey|prey bait|bait UBE2E1 RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102537|BIOGRID_123547 bait|bait prey|prey UBE2D3 RNF150 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123491|UniProt_102481 bait|bait prey|prey UBE2D2 RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102445|BIOGRID_123457 bait|bait prey|prey UBE2U RNF150 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123663|UniProt_102652 bait|bait prey|prey UBE2E3 RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102555|BIOGRID_123566 bait|bait prey|prey UBE2L6 RNF150 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123602|UniProt_102591 bait|bait prey|prey UBE2W RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102691|BIOGRID_123702 bait|bait prey|prey UBE2Z RNF150 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123717|UniProt_102706 bait|bait prey|prey UBE2D1 RNF150 MI:0397(two hybrid array)|MI:0018(two hybrid) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_102417|BIOGRID_123428 bait|bait prey|prey ELAVL1 RNF150 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187284 bait prey

PPI - HINT Gene A Gene B PMID Method Quality UBE2L6 RNF150 19690564,19690564 0397,0018 HT UBE2D1 RNF150 19690564,19690564 0397,0018 HT UBE2E1 RNF150 19690564,19690564 0397,0018 HT UBE2D3 RNF150 19690564,19690564 0397,0018 HT UBE2D2 RNF150 19690564,19690564 0397,0018 HT UBE2U RNF150 19690564,19690564 0397,0018 HT UBE2E3 RNF150 19690564,19690564 0397,0018 HT UBE2W RNF150 19690564,19690564 0397,0018 HT UBE2Z RNF150 19690564,19690564 0397,0018 HT RNF150 UBE2D4 19690564,19690564 0397,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9ULK6 Q9HCE1 RNF150 MOV10 0.126 22658674 Q9ULK6 Q9H832 RNF150 UBE2Z 0.286 19690564 Q9ULK6 Q96B02 RNF150 UBE2W 0.286 19690564 Q9ULK6 P62837 RNF150 UBE2D2 0.286 19690564 Q9ULK6 O14933 RNF150 UBE2L6 0.376 19690564 Q9ULK6 P51668 RNF150 UBE2D1 0.376 19690564 Q9ULK6 P51965 RNF150 UBE2E1 0.286 19690564 Q9ULK6 P61077 RNF150 UBE2D3 0.376 19690564 Q9ULK6 Q5VVX9 RNF150 UBE2U 0.376 19690564 Q9ULK6 Q969T4 RNF150 UBE2E3 0.376 19690564 Q9Y2X8 Q9ULK6 UBE2D4 RNF150 0.376 19690564 Q9ULK6 Q15717 RNF150 ELAVL1 0.126 19322201

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBE2L6 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E1 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D3 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2U RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2W RNF150 MI:0045 experimental interaction detection MI:0461 interaction database UBE2Z RNF150 MI:0045 experimental interaction detection MI:0461 interaction database MOV10 RNF150 MI:0045 experimental interaction detection MI:0461 interaction database RNF150 UBE2D4 MI:0045 experimental interaction detection MI:0461 interaction database