Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BRCA 11 119206393 119206393 + Silent SNP C C T TCGA-AO-A124-01A-11D-A10M-09 TCGA-AO-A124-10A-01D-A10M-09 g.chr11:119206393C>T c.561C>T c.(559-561)ttC>ttT p.F187F BRCA 11 119206924 119206924 + Silent SNP G G A TCGA-BH-A18G-01A-11D-A12B-09 TCGA-BH-A18G-10A-01D-A12B-09 g.chr11:119206924G>A c.1092G>A c.(1090-1092)ggG>ggA p.G364G CESC 11 119206814 119206814 + Missense_Mutation SNP C C T TCGA-EA-A44S-01A-12D-A26G-09 TCGA-EA-A44S-10A-01D-A26G-09 g.chr11:119206814C>T c.982C>T c.(982-984)Ctt>Ttt p.L328F CESC 11 119207071 119207071 + Silent SNP C C T TCGA-DR-A0ZM-01A-12D-A10S-08 TCGA-DR-A0ZM-10A-01D-A10S-08 g.chr11:119207071C>T c.1239C>T c.(1237-1239)gtC>gtT p.V413V CESC 11 119207121 119207121 + Missense_Mutation SNP A A C TCGA-FU-A3HZ-01A-11D-A20U-09 TCGA-FU-A3HZ-10A-01D-A20U-09 g.chr11:119207121A>C c.1289A>C c.(1288-1290)aAt>aCt p.N430T COAD 11 119205973 119205973 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr11:119205973G>A c.141G>A c.(139-141)ccG>ccA p.P47P COAD 11 119206049 119206049 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr11:119206049G>A c.217G>A c.(217-219)Gtc>Atc p.V73I COAD 11 119206223 119206223 + Missense_Mutation SNP C C T TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr11:119206223C>T c.391C>T c.(391-393)Cgc>Tgc p.R131C COAD 11 119207119 119207119 + Silent SNP C C T TCGA-D5-6539-01A-11D-1719-10 TCGA-D5-6539-10A-01D-1719-10 g.chr11:119207119C>T c.1287C>T c.(1285-1287)ctC>ctT p.L429L COADREAD 11 119205973 119205973 + Silent SNP G G A TCGA-AZ-6598-01A-11D-1771-10 TCGA-AZ-6598-11A-01D-1771-10 g.chr11:119205973G>A c.141G>A c.(139-141)ccG>ccA p.P47P COADREAD 11 119205979 119205979 + Silent SNP G G A TCGA-DY-A1DD-01A-21D-A152-10 TCGA-DY-A1DD-10A-01D-A152-10 g.chr11:119205979G>A c.147G>A c.(145-147)acG>acA p.T49T COADREAD 11 119206049 119206049 + Missense_Mutation SNP G G A TCGA-AD-6895-01A-11D-1924-10 TCGA-AD-6895-10A-01D-1924-10 g.chr11:119206049G>A c.217G>A c.(217-219)Gtc>Atc p.V73I COADREAD 11 119206223 119206223 + Missense_Mutation SNP C C T TCGA-AD-5900-01A-11D-1650-10 TCGA-AD-5900-10A-01D-1650-10 g.chr11:119206223C>T c.391C>T c.(391-393)Cgc>Tgc p.R131C COADREAD 11 119207119 119207119 + Silent SNP C C T TCGA-D5-6539-01A-11D-1719-10 TCGA-D5-6539-10A-01D-1719-10 g.chr11:119207119C>T c.1287C>T c.(1285-1287)ctC>ctT p.L429L DLBC 11 119206427 119206427 + Missense_Mutation SNP G G A TCGA-G8-6909-01A-11D-2210-10 TCGA-G8-6909-14A-01D-2210-10 g.chr11:119206427G>A c.595G>A c.(595-597)Gcc>Acc p.A199T ESCA 11 119206725 119206725 + Missense_Mutation SNP C C T TCGA-L5-A88T-01A-11D-A351-09 TCGA-L5-A88T-11A-11D-A351-09 g.chr11:119206725C>T c.893C>T c.(892-894)gCg>gTg p.A298V GBM 11 119206097 119206097 + Missense_Mutation SNP A A G TCGA-06-5858-01A-01D-1696-08 TCGA-06-5858-10A-01D-1696-08 g.chr11:119206097A>G c.265A>G c.(265-267)Agc>Ggc p.S89G GBM 11 119206267 119206267 + Silent SNP T T A TCGA-32-2491-01A-01D-1353-08 TCGA-32-2491-10A-01D-1353-08 g.chr11:119206267T>A c.435T>A c.(433-435)gcT>gcA p.A145A GBMLGG 11 119206053 119206053 + Missense_Mutation SNP G G T TCGA-P5-A72W-01A-11D-A32B-08 TCGA-P5-A72W-10A-01D-A329-08 g.chr11:119206053G>T c.221G>T c.(220-222)cGg>cTg p.R74L GBMLGG 11 119206097 119206097 + Missense_Mutation SNP A A G TCGA-06-5858-01A-01D-1696-08 TCGA-06-5858-10A-01D-1696-08 g.chr11:119206097A>G c.265A>G c.(265-267)Agc>Ggc p.S89G GBMLGG 11 119206267 119206267 + Silent SNP T T A TCGA-32-2491-01A-01D-1353-08 TCGA-32-2491-10A-01D-1353-08 g.chr11:119206267T>A c.435T>A c.(433-435)gcT>gcA p.A145A KIPAN 11 119205888 119205888 + Missense_Mutation SNP C C A TCGA-CZ-5468-01A-01D-1501-10 TCGA-CZ-5468-11A-01D-1501-10 g.chr11:119205888C>A c.56C>A c.(55-57)aCc>aAc p.T19N KIPAN 11 119206410 119206410 + Missense_Mutation SNP G G A TCGA-A4-7734-01A-11D-2136-08 TCGA-A4-7734-10A-01D-2136-08 g.chr11:119206410G>A c.578G>A c.(577-579)aGc>aAc p.S193N KIPAN 11 119206568 119206568 + Missense_Mutation SNP C C A TCGA-5P-A9KA-01A-11D-A42J-10 TCGA-5P-A9KA-10A-01D-A42M-10 g.chr11:119206568C>A c.736C>A c.(736-738)Cat>Aat p.H246N KIRC 11 119205888 119205888 + Missense_Mutation SNP C C A TCGA-CZ-5468-01A-01D-1501-10 TCGA-CZ-5468-11A-01D-1501-10 g.chr11:119205888C>A c.56C>A c.(55-57)aCc>aAc p.T19N KIRP 11 119206410 119206410 + Missense_Mutation SNP G G A TCGA-A4-7734-01A-11D-2136-08 TCGA-A4-7734-10A-01D-2136-08 g.chr11:119206410G>A c.578G>A c.(577-579)aGc>aAc p.S193N KIRP 11 119206568 119206568 + Missense_Mutation SNP C C A TCGA-5P-A9KA-01A-11D-A42J-10 TCGA-5P-A9KA-10A-01D-A42M-10 g.chr11:119206568C>A c.736C>A c.(736-738)Cat>Aat p.H246N LGG 11 119206053 119206053 + Missense_Mutation SNP G G T TCGA-P5-A72W-01A-11D-A32B-08 TCGA-P5-A72W-10A-01D-A329-08 g.chr11:119206053G>T c.221G>T c.(220-222)cGg>cTg p.R74L LIHC 11 119206381 119206381 + Silent SNP A A G TCGA-DD-A3A8-01A-11D-A22F-10 TCGA-DD-A3A8-11A-11D-A22F-10 g.chr11:119206381A>G c.549A>G c.(547-549)gtA>gtG p.V183V LIHC 11 119206969 119206969 + Missense_Mutation SNP G G C TCGA-BC-A112-01A-11D-A12Z-10 TCGA-BC-A112-11A-11D-A12Z-10 g.chr11:119206969G>C c.1137G>C c.(1135-1137)aaG>aaC p.K379N LUAD 11 119206045 119206045 + Silent SNP C C T TCGA-86-A4JF-01A-11D-A24P-08 TCGA-86-A4JF-10A-01D-A24P-08 g.chr11:119206045C>T c.213C>T c.(211-213)gcC>gcT p.A71A LUAD 11 119206115 119206115 + Missense_Mutation SNP G G A TCGA-75-5126-01A-01D-1753-08 TCGA-75-5126-10A-01D-1753-08 g.chr11:119206115G>A c.283G>A c.(283-285)Gag>Aag p.E95K LUAD 11 119206355 119206355 + Missense_Mutation SNP G G T TCGA-73-7498-01A-12D-2184-08 TCGA-73-7498-10A-01D-2184-08 g.chr11:119206355G>T c.523G>T c.(523-525)Ggg>Tgg p.G175W LUAD 11 119207086 119207086 + Silent SNP C C T TCGA-64-1676-01A-01D-0969-08 TCGA-64-1676-10A-01D-0969-08 g.chr11:119207086C>T c.1254C>T c.(1252-1254)tgC>tgT p.C418C LUSC 11 119206134 119206134 + Missense_Mutation SNP G G A TCGA-22-5480-01A-01D-1632-08 TCGA-22-5480-11A-01D-1632-08 g.chr11:119206134G>A c.302G>A c.(301-303)gGg>gAg p.G101E LUSC 11 119206154 119206154 + Missense_Mutation SNP G G C TCGA-66-2782-01A-01D-1522-08 TCGA-66-2782-11A-01D-1522-08 g.chr11:119206154G>C c.322G>C c.(322-324)Gca>Cca p.A108P LUSC 11 119206720 119206720 + Missense_Mutation SNP G G C TCGA-33-4532-01A-01D-1267-08 TCGA-33-4532-11A-01D-1267-08 g.chr11:119206720G>C c.888G>C c.(886-888)caG>caC p.Q296H OV 11 119206996 119206996 + Silent SNP G G A TCGA-24-1563-01A-01W-0553-09 TCGA-24-1563-10A-01W-0553-09 g.chr11:119206996G>A c.1164G>A c.(1162-1164)aaG>aaA p.K388K PAAD 11 119206987 119206987 + Silent SNP C C T TCGA-LB-A7SX-01A-11D-A33T-08 TCGA-LB-A7SX-10A-01D-A33W-08 g.chr11:119206987C>T c.1155C>T c.(1153-1155)gaC>gaT p.D385D PRAD 11 119207000 119207000 + Missense_Mutation SNP G G T TCGA-CH-5771-01A-21D-1576-08 TCGA-CH-5771-11A-01D-1576-08 g.chr11:119207000G>T c.1168G>T c.(1168-1170)Gtg>Ttg p.V390L READ 11 119205979 119205979 + Silent SNP G G A TCGA-DY-A1DD-01A-21D-A152-10 TCGA-DY-A1DD-10A-01D-A152-10 g.chr11:119205979G>A c.147G>A c.(145-147)acG>acA p.T49T SKCM 11 119206803 119206803 + Missense_Mutation SNP G G A TCGA-EE-A3JE-06A-11D-A20D-08 TCGA-EE-A3JE-10A-01D-A20D-08 g.chr11:119206803G>A c.971G>A c.(970-972)aGa>aAa p.R324K SKCM 11 119207129 119207129 + Missense_Mutation SNP C C T TCGA-DA-A1I0-06A-11D-A20D-08 TCGA-DA-A1I0-10B-01D-A20D-08 g.chr11:119207129C>T c.1297C>T c.(1297-1299)Ctc>Ttc p.L433F

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 11 119206123 119206123 single base substitution A G synonymous_variant L97L 291A>G BLCA-CN 11 119212410 119212410 single base substitution G A downstream_gene_variant BLCA-US 11 119212284 119212284 single base substitution C T downstream_gene_variant BLCA-US 11 119212379 119212379 single base substitution G C downstream_gene_variant BRCA-EU 11 119200787 119200787 single base substitution C G upstream_gene_variant BRCA-EU 11 119201568 119201568 single base substitution C G upstream_gene_variant BRCA-EU 11 119201593 119201593 single base substitution G T upstream_gene_variant BRCA-EU 11 119204792 119204792 single base substitution A G upstream_gene_variant BRCA-EU 11 119206786 119206786 single base substitution C A missense_variant F318L 954C>A BRCA-EU 11 119206900 119206900 single base substitution C T synonymous_variant L356L 1068C>T BRCA-EU 11 119208711 119208711 deletion of <=200bp C - downstream_gene_variant BRCA-EU 11 119212894 119212894 single base substitution G A downstream_gene_variant BRCA-FR 11 119200787 119200787 single base substitution C G upstream_gene_variant BRCA-FR 11 119201593 119201593 single base substitution G T upstream_gene_variant BRCA-KR 11 119210393 119210393 single base substitution C T downstream_gene_variant BRCA-US 11 119206393 119206393 single base substitution C T synonymous_variant F187F 561C>T BRCA-US 11 119206924 119206924 single base substitution G A synonymous_variant G364G 1092G>A BRCA-US 11 119210189 119210189 insertion of <=200bp - C downstream_gene_variant BRCA-US 11 119210295 119210295 single base substitution A G downstream_gene_variant BTCA-JP 11 119205735 119205735 single base substitution T C 5_prime_UTR_variant BTCA-JP 11 119211068 119211068 single base substitution C T downstream_gene_variant CESC-US 11 119206814 119206814 single base substitution C T missense_variant L328F 982C>T CESC-US 11 119207071 119207071 single base substitution C T synonymous_variant V413V 1239C>T CESC-US 11 119207121 119207121 single base substitution A C missense_variant N430T 1289A>C CESC-US 11 119209810 119209810 single base substitution G T downstream_gene_variant CESC-US 11 119209986 119209986 single base substitution C T downstream_gene_variant CESC-US 11 119212390 119212390 single base substitution G T downstream_gene_variant COAD-US 11 119205973 119205973 single base substitution G A synonymous_variant P47P 141G>A COAD-US 11 119206049 119206049 single base substitution G A missense_variant V73I 217G>A COAD-US 11 119206223 119206223 single base substitution C T missense_variant R131C 391C>T COAD-US 11 119206375 119206375 single base substitution G A synonymous_variant T181T 543G>A COAD-US 11 119210189 119210189 insertion of <=200bp - C downstream_gene_variant COAD-US 11 119210352 119210352 single base substitution C T downstream_gene_variant COAD-US 11 119211081 119211081 single base substitution G C downstream_gene_variant COAD-US 11 119212463 119212463 single base substitution C T downstream_gene_variant COAD-US 11 119212640 119212640 single base substitution G A downstream_gene_variant COCA-CN 11 119205735 119205735 single base substitution T C 5_prime_UTR_variant COCA-CN 11 119210299 119210299 single base substitution G A downstream_gene_variant COCA-CN 11 119210583 119210583 single base substitution G T downstream_gene_variant ESAD-UK 11 119203599 119203599 single base substitution A C upstream_gene_variant ESAD-UK 11 119203753 119203753 single base substitution G T upstream_gene_variant ESAD-UK 11 119203811 119203811 single base substitution G A upstream_gene_variant ESAD-UK 11 119204969 119204969 single base substitution C A upstream_gene_variant ESAD-UK 11 119205185 119205185 single base substitution T G upstream_gene_variant ESAD-UK 11 119207340 119207340 single base substitution C T 3_prime_UTR_variant ESAD-UK 11 119209218 119209218 single base substitution G C downstream_gene_variant GBM-US 11 119206097 119206097 single base substitution A G missense_variant S89G 265A>G GBM-US 11 119206267 119206267 single base substitution T A synonymous_variant A145A 435T>A GBM-US 11 119212361 119212361 single base substitution T G downstream_gene_variant KIRC-US 11 119205888 119205888 single base substitution C A missense_variant T19N 56C>A KIRC-US 11 119212284 119212284 single base substitution C A downstream_gene_variant KIRP-US 11 119206410 119206410 single base substitution G A missense_variant S193N 578G>A KIRP-US 11 119210071 119210071 single base substitution G C downstream_gene_variant LICA-FR 11 119201256 119201256 single base substitution C T upstream_gene_variant LICA-FR 11 119212369 119212369 single base substitution C T downstream_gene_variant LIHC-US 11 119206381 119206381 single base substitution A G synonymous_variant V183V 549A>G LIHC-US 11 119206969 119206969 single base substitution G C missense_variant K379N 1137G>C LINC-JP 11 119211264 119211264 single base substitution C A downstream_gene_variant LINC-JP 11 119211638 119211638 single base substitution C T downstream_gene_variant LIRI-JP 11 119203874 119203874 single base substitution G A upstream_gene_variant LIRI-JP 11 119204096 119204096 single base substitution G A upstream_gene_variant LIRI-JP 11 119205012 119205012 single base substitution G A upstream_gene_variant LIRI-JP 11 119208014 119208014 single base substitution C T 3_prime_UTR_variant LIRI-JP 11 119209805 119209805 single base substitution G A downstream_gene_variant LIRI-JP 11 119210190 119210190 insertion of <=200bp - C downstream_gene_variant LIRI-JP 11 119212646 119212646 single base substitution T C downstream_gene_variant LUSC-KR 11 119205315 119205315 single base substitution T C 5_prime_UTR_premature_start_codon_gain_variant LUSC-KR 11 119206081 119206081 single base substitution G A synonymous_variant L83L 249G>A LUSC-KR 11 119206824 119206824 single base substitution C T missense_variant A331V 992C>T LUSC-KR 11 119206939 119206939 single base substitution A G synonymous_variant K369K 1107A>G LUSC-KR 11 119207718 119207718 single base substitution T G 3_prime_UTR_variant LUSC-KR 11 119207969 119207969 single base substitution G C 3_prime_UTR_variant LUSC-KR 11 119210827 119210827 single base substitution G T downstream_gene_variant LUSC-US 11 119206134 119206134 single base substitution G A missense_variant G101E 302G>A LUSC-US 11 119206154 119206154 single base substitution G C missense_variant A108P 322G>C LUSC-US 11 119206720 119206720 single base substitution G C missense_variant Q296H 888G>C MALY-DE 11 119205847 119205847 single base substitution C A stop_gained Y5* 15C>A MELA-AU 11 119200288 119200288 single base substitution G A upstream_gene_variant MELA-AU 11 119200587 119200587 single base substitution G T upstream_gene_variant MELA-AU 11 119200805 119200805 single base substitution G A upstream_gene_variant MELA-AU 11 119201099 119201099 single base substitution C T upstream_gene_variant MELA-AU 11 119201289 119201289 single base substitution C T upstream_gene_variant MELA-AU 11 119201762 119201762 single base substitution C G upstream_gene_variant MELA-AU 11 119201928 119201928 single base substitution C G upstream_gene_variant MELA-AU 11 119201944 119201944 single base substitution G A upstream_gene_variant MELA-AU 11 119202017 119202017 single base substitution G A upstream_gene_variant MELA-AU 11 119202327 119202327 single base substitution C T upstream_gene_variant MELA-AU 11 119202463 119202463 single base substitution T C upstream_gene_variant MELA-AU 11 119202571 119202571 single base substitution T A upstream_gene_variant MELA-AU 11 119202607 119202607 single base substitution C T upstream_gene_variant MELA-AU 11 119202973 119202973 single base substitution C T upstream_gene_variant MELA-AU 11 119203193 119203193 single base substitution C T upstream_gene_variant MELA-AU 11 119203382 119203382 single base substitution G A upstream_gene_variant MELA-AU 11 119203406 119203406 single base substitution G A upstream_gene_variant MELA-AU 11 119203414 119203414 single base substitution C T upstream_gene_variant MELA-AU 11 119203466 119203466 single base substitution G A upstream_gene_variant MELA-AU 11 119203673 119203673 single base substitution G A upstream_gene_variant MELA-AU 11 119203735 119203735 single base substitution A C upstream_gene_variant MELA-AU 11 119203774 119203774 single base substitution C T upstream_gene_variant MELA-AU 11 119205069 119205069 single base substitution G A upstream_gene_variant MELA-AU 11 119205096 119205096 single base substitution C T upstream_gene_variant MELA-AU 11 119205174 119205174 single base substitution C T upstream_gene_variant MELA-AU 11 119205198 119205198 single base substitution C T upstream_gene_variant MELA-AU 11 119205209 119205209 single base substitution C T upstream_gene_variant MELA-AU 11 119205217 119205217 single base substitution C T upstream_gene_variant MELA-AU 11 119205746 119205746 single base substitution C T 5_prime_UTR_variant MELA-AU 11 119205890 119205890 insertion of <=200bp - TTGGT frameshift_variant L20LV? MELA-AU 11 119207500 119207500 single base substitution C T 3_prime_UTR_variant MELA-AU 11 119207836 119207836 single base substitution C T 3_prime_UTR_variant MELA-AU 11 119207878 119207878 single base substitution C T 3_prime_UTR_variant MELA-AU 11 119207991 119207991 single base substitution T A 3_prime_UTR_variant MELA-AU 11 119208007 119208007 single base substitution C T 3_prime_UTR_variant MELA-AU 11 119208365 119208365 single base substitution C T downstream_gene_variant MELA-AU 11 119208952 119208952 single base substitution G A downstream_gene_variant MELA-AU 11 119210693 119210693 single base substitution C T downstream_gene_variant MELA-AU 11 119211552 119211553 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 11 119212961 119212961 single base substitution G A downstream_gene_variant ORCA-IN 11 119200455 119200455 single base substitution G C upstream_gene_variant ORCA-IN 11 119208264 119208264 single base substitution C T downstream_gene_variant OV-AU 11 119204036 119204036 single base substitution C T upstream_gene_variant OV-AU 11 119204271 119204271 single base substitution C T upstream_gene_variant OV-AU 11 119204602 119204602 single base substitution A C upstream_gene_variant OV-AU 11 119208799 119208799 single base substitution T G downstream_gene_variant OV-AU 11 119210016 119210016 single base substitution G T downstream_gene_variant OV-AU 11 119211403 119211403 single base substitution A C downstream_gene_variant OV-AU 11 119211987 119211987 single base substitution G T downstream_gene_variant OV-US 11 119206996 119206996 single base substitution G A synonymous_variant K388K 1164G>A PACA-AU 11 119201260 119201260 single base substitution C A upstream_gene_variant PACA-CA 11 119206090 119206090 single base substitution G C synonymous_variant L86L 258G>C PACA-CA 11 119206644 119206644 single base substitution G A missense_variant R271Q 812G>A PACA-CA 11 119207318 119207318 single base substitution C T 3_prime_UTR_variant PACA-CA 11 119207525 119207525 single base substitution C T 3_prime_UTR_variant PACA-CA 11 119210460 119210460 single base substitution C T downstream_gene_variant PBCA-DE 11 119201171 119201175 deletion of <=200bp TTTCT - upstream_gene_variant PBCA-DE 11 119206910 119206910 single base substitution G A missense_variant E360K 1078G>A PBCA-DE 11 119211108 119211108 single base substitution A T downstream_gene_variant PRAD-CA 11 119202358 119202358 single base substitution C G upstream_gene_variant PRAD-US 11 119207000 119207000 single base substitution G T missense_variant V390L 1168G>T READ-US 11 119205973 119205973 single base substitution G A synonymous_variant P47P 141G>A READ-US 11 119205979 119205979 single base substitution G A synonymous_variant T49T 147G>A READ-US 11 119206142 119206142 single base substitution G A missense_variant A104T 310G>A RECA-EU 11 119203348 119203348 single base substitution G A upstream_gene_variant RECA-EU 11 119205656 119205656 single base substitution A G 5_prime_UTR_premature_start_codon_gain_variant SKCA-BR 11 119201342 119201342 single base substitution C T upstream_gene_variant SKCA-BR 11 119201999 119201999 single base substitution C T upstream_gene_variant SKCA-BR 11 119202211 119202211 single base substitution C T upstream_gene_variant SKCA-BR 11 119203423 119203423 single base substitution G A upstream_gene_variant SKCA-BR 11 119204600 119204600 single base substitution G A upstream_gene_variant SKCA-BR 11 119205122 119205122 single base substitution G A upstream_gene_variant SKCA-BR 11 119205156 119205157 deletion of <=200bp GT - upstream_gene_variant SKCA-BR 11 119205219 119205219 single base substitution C T upstream_gene_variant SKCA-BR 11 119205902 119205902 single base substitution C A missense_variant L24I 70C>A SKCA-BR 11 119207752 119207752 single base substitution C T 3_prime_UTR_variant SKCA-BR 11 119208377 119208377 single base substitution C T downstream_gene_variant SKCA-BR 11 119209582 119209582 single base substitution A C downstream_gene_variant SKCA-BR 11 119210642 119210642 single base substitution T C downstream_gene_variant SKCA-BR 11 119211236 119211236 single base substitution A C downstream_gene_variant SKCA-BR 11 119211370 119211370 single base substitution T C downstream_gene_variant SKCA-BR 11 119211854 119211854 single base substitution G T downstream_gene_variant SKCM-US 11 119206803 119206803 single base substitution G A missense_variant R324K 971G>A SKCM-US 11 119207129 119207129 single base substitution C T missense_variant L433F 1297C>T SKCM-US 11 119212430 119212430 single base substitution A C downstream_gene_variant STAD-US 11 119205959 119205959 single base substitution G A missense_variant V43I 127G>A STAD-US 11 119206040 119206040 single base substitution G A missense_variant E70K 208G>A STAD-US 11 119206667 119206667 single base substitution C T missense_variant R279C 835C>T STAD-US 11 119206681 119206681 single base substitution C A synonymous_variant G283G 849C>A STAD-US 11 119206740 119206740 single base substitution G A missense_variant R303Q 908G>A STAD-US 11 119206877 119206877 single base substitution C T missense_variant P349S 1045C>T STAD-US 11 119207069 119207069 single base substitution G A missense_variant V413I 1237G>A STAD-US 11 119207088 119207088 single base substitution C T missense_variant P419L 1256C>T STAD-US 11 119210190 119210190 insertion of <=200bp - C downstream_gene_variant STAD-US 11 119212402 119212402 single base substitution G A downstream_gene_variant STAD-US 11 119212679 119212679 single base substitution G T downstream_gene_variant THCA-SA 11 119207172 119207172 single base substitution C T 3_prime_UTR_variant UCEC-US 11 119205772 119205772 single base substitution C A 5_prime_UTR_variant UCEC-US 11 119206365 119206365 single base substitution G A stop_gained W178* 533G>A UCEC-US 11 119206726 119206726 single base substitution G A synonymous_variant A298A 894G>A UCEC-US 11 119206936 119206936 single base substitution G A stop_gained W368* 1104G>A UCEC-US 11 119210089 119210089 single base substitution G A downstream_gene_variant UCEC-US 11 119210105 119210105 single base substitution G C downstream_gene_variant UCEC-US 11 119210202 119210202 single base substitution G A downstream_gene_variant UCEC-US 11 119212624 119212624 insertion of <=200bp - T downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand SNUH_G16_S1 COSM3998258 c.1080G>T p.E360D Substitution - Missense 11:119336202-119336202 + SNUH_G10_S1 COSM3998259 c.1107A>G p.K369K Substitution - coding silent 11:119336229-119336229 + TCGA-CZ-5468-01 COSM466453 c.56C>A p.T19N Substitution - Missense 11:119335178-119335178 + TCGA-DR-A0ZM-01 COSM458711 c.1239C>T p.V413V Substitution - coding silent 11:119336361-119336361 + TCGA-AZ-6598-01 COSM1351862 c.141G>A p.P47P Substitution - coding silent 11:119335263-119335263 + TCGA-32-2491-01 COSM3397470 c.435T>A p.A145A Substitution - coding silent 11:119335557-119335557 + TCGA-BR-6452-01 COSM4018527 c.127G>A p.V43I Substitution - Missense 11:119335249-119335249 + T578 COSM4722178 c.998G>A p.R333H Substitution - Missense 11:119336120-119336120 + Pat_41_B COSM5837988 c.484C>T p.L162F Substitution - Missense 11:119335606-119335606 + SNU-C4 COSM4651876 c.1265G>A p.R422H Substitution - Missense 11:119336387-119336387 + LUAD-YINHD COSM348350 c.720G>A p.V240V Substitution - coding silent 11:119335842-119335842 + YUDON COSM5371807 c.1221C>T p.I407I Substitution - coding silent 11:119336343-119336343 + CSCC-55-T COSM4515859 c.135_136CC>TT p.(=) Unknown 11:119335257-119335258 + T3535 COSM4722177 c.767A>G p.Q256R Substitution - Missense 11:119335889-119335889 + T3021 COSM4745585 c.998_999GC>AT p.R333H Substitution - Missense 11:119336120-119336121 + MO_1012 COSM5554330 c.223T>G p.F75V Substitution - Missense 11:119335345-119335345 + TCGA-BH-A18G-01 COSM3808562 c.1092G>A p.G364G Substitution - coding silent 11:119336214-119336214 + TCGA-AX-A0J0-01 COSM923836 c.894G>A p.A298A Substitution - coding silent 11:119336016-119336016 + TCGA-F1-6177-01 COSM4018534 c.1256C>T p.P419L Substitution - Missense 11:119336378-119336378 + TCGA-DY-A1DD-01 COSM1561579 c.147G>A p.T49T Substitution - coding silent 11:119335269-119335269 + TCGA-D1-A17H-01 COSM923835 c.533G>A p.W178* Substitution - Nonsense 11:119335655-119335655 + pfg057T COSM4760620 c.884T>C p.L295P Substitution - Missense 11:119336006-119336006 + TCGA-DA-A1I0-06 COSM3444175 c.1297C>T p.L433F Substitution - Missense 11:119336419-119336419 + 35M COSM5582382 c.488T>A p.F163Y Substitution - Missense 11:119335610-119335610 + PT42 COSM5925631 c.784C>T p.H262Y Substitution - Missense 11:119335906-119335906 + A673 COSM2106846 c.49G>A p.V17M Substitution - Missense 11:119335171-119335171 + TCGA-A4-7734-01 COSM3985989 c.578G>A p.S193N Substitution - Missense 11:119335700-119335700 + ML_77_T_01 COSM5033979 c.70C>A p.L24I Substitution - Missense 11:119335192-119335192 + 587284 COSM1223994 c.1276C>A p.L426M Substitution - Missense 11:119336398-119336398 + Gp5D COSM2106859 c.878G>A p.R293H Substitution - Missense 11:119336000-119336000 + 1946219 COSM1578233 c.596C>A p.A199D Substitution - Missense 11:119335718-119335718 + SNUH_G10_S1 COSM3998257 c.249G>A p.L83L Substitution - coding silent 11:119335371-119335371 + CSCC-29-T COSM4508880 c.78C>T p.F26F Substitution - coding silent 11:119335200-119335200 + MO_1012 COSM5551398 c.268T>A p.C90S Substitution - Missense 11:119335390-119335390 + TCGA-AD-5900-01 COSM1351864 c.391C>T p.R131C Substitution - Missense 11:119335513-119335513 + TCGA-AM-5821-01 COSM3752177 c.543G>A p.T181T Substitution - coding silent 11:119335665-119335665 + B52 COSM1746085 c.291A>G p.L97L Substitution - coding silent 11:119335413-119335413 + TCGA-BC-A112-01 COSM4936414 c.1137G>C p.K379N Substitution - Missense 11:119336259-119336259 + TCGA-HU-A4H3-01 COSM4018533 c.1237G>A p.V413I Substitution - Missense 11:119336359-119336359 + TCGA-CD-A4MG-01 COSM4018532 c.1045C>T p.P349S Substitution - Missense 11:119336167-119336167 + TCGA-66-2782-01 COSM686893 c.322G>C p.A108P Substitution - Missense 11:119335444-119335444 + TCGA-F5-6814-01 COSM1351862 c.141G>A p.P47P Substitution - coding silent 11:119335263-119335263 + TCGA-AO-A124-01 COSM428544 c.561C>T p.F187F Substitution - coding silent 11:119335683-119335683 + TCGA-EI-6917-01 COSM3415598 c.310G>A p.A104T Substitution - Missense 11:119335432-119335432 + SNU-175 COSM2106854 c.653G>A p.R218H Substitution - Missense 11:119335775-119335775 + 6115117 COSM1351864 c.391C>T p.R131C Substitution - Missense 11:119335513-119335513 + TCGA-22-5480-01 COSM686894 c.302G>A p.G101E Substitution - Missense 11:119335424-119335424 + TCGA-EE-A3JE-06 COSM3868564 c.971G>A p.R324K Substitution - Missense 11:119336093-119336093 + SC_9083 COSM5555221 c.913G>C p.G305R Substitution - Missense 11:119336035-119336035 + TCGA-DD-A3A8-01 COSM4934943 c.549A>G p.V183V Substitution - coding silent 11:119335671-119335671 + TCGA-BR-8059-01 COSM4018528 c.208G>A p.E70K Substitution - Missense 11:119335330-119335330 + TCGA-33-4532-01 COSM686891 c.888G>C p.Q296H Substitution - Missense 11:119336010-119336010 + 449 COSM4435327 c.204G>A p.L68L Substitution - coding silent 11:119335326-119335326 + TCGA-D1-A16X-01 COSM923837 c.1104G>A p.W368* Substitution - Nonsense 11:119336226-119336226 + TCGA-BR-A4QL-01 COSM4018530 c.849C>A p.G283G Substitution - coding silent 11:119335971-119335971 + pfg009T COSM1638754 c.341T>C p.I114T Substitution - Missense 11:119335463-119335463 + ESCC_142 COSM5643672 c.61G>T p.V21L Substitution - Missense 11:119335183-119335183 + TCGA-BR-8382-01 COSM4018531 c.908G>A p.R303Q Substitution - Missense 11:119336030-119336030 + ESCC_76 COSM5635053 c.883C>T p.L295L Substitution - coding silent 11:119336005-119336005 + TCGA-FU-A3HZ-01 COSM4839227 c.1289A>C p.N430T Substitution - Missense 11:119336411-119336411 + Pat_53_B COSM5837987 c.236G>A p.G79D Substitution - Missense 11:119335358-119335358 + Gp2D COSM2106859 c.878G>A p.R293H Substitution - Missense 11:119336000-119336000 + 61 COSM5739479 c.968G>A p.R323Q Substitution - Missense 11:119336090-119336090 + S01170 COSM5666983 c.320G>T p.G107V Substitution - Missense 11:119335442-119335442 + TCGA-CH-5771-01 COSM1127885 c.1168G>T p.V390L Substitution - Missense 11:119336290-119336290 + tumor_4105746 COSM5946553 c.15C>A p.Y5* Substitution - Nonsense 11:119335137-119335137 + TCGA-EA-A44S-01 COSM4822078 c.982C>T p.L328F Substitution - Missense 11:119336104-119336104 + D28 COSM5545715 c.492C>T p.S164S Substitution - coding silent 11:119335614-119335614 + B52-Tumor COSM1746085 c.291A>G p.L97L Substitution - coding silent 11:119335413-119335413 + TCGA-HF-7136-01 COSM4018529 c.835C>T p.R279C Substitution - Missense 11:119335957-119335957 + TCGA-AD-6895-01 COSM1351863 c.217G>A p.V73I Substitution - Missense 11:119335339-119335339 + TCGA-06-5858-01 COSM3397469 c.265A>G p.S89G Substitution - Missense 11:119335387-119335387 + C086 COSM5538303 c.1222C>T p.L408L Substitution - coding silent 11:119336344-119336344 + TCGA-24-1563-01 COSM81665 c.1164G>A p.K388K Substitution - coding silent 11:119336286-119336286 + S01170 COSM5666984 c.1237G>T p.V413F Substitution - Missense 11:119336359-119336359 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.524084 11q23 606130 2398842|CGAP|BC000058|C/T|non-coding||2487|Validated; 2398842|CGAP|BC007534|C/T|non-coding||2458|Validated; 2398850|CGAP|BC000058|A/G|coding|Thr181Thr|934|Validated; 2398850|CGAP|BC007534|A/G|coding|Thr181Thr|905|Validated Hs.741372 11q23 606130 2398842|CGAP|BC000058|C/T|non-coding||2487|Validated; 2398842|CGAP|BC007534|C/T|non-coding||2458|Validated; 2398850|CGAP|BC000058|A/G|coding|Thr181Thr|934|Validated; 2398850|CGAP|BC007534|A/G|coding|Thr181Thr|905|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer C A Missense p.L429I c.1285C>A 11 119207117 STAD C A Missense p.T19N c.56C>A 11 119205888 RCCC C A Synonymous p.R264R c.790C>A 11 119206622 STAD C T Missense p.L433F c.1297C>T 11 119207129 CM C T Missense p.P419L c.1256C>T 11 119207088 STAD C T Synonymous p.C418C c.1254C>T 11 119207086 LUAD C T Synonymous p.F187F c.561C>T 11 119206393 BRCA G A Missense p.A239T c.715G>A 11 119206547 CM G A Missense p.E95K c.283G>A 11 119206115 LUAD G A Missense p.G101E c.302G>A 11 119206134 LUSC G A Missense p.R324K c.971G>A 11 119206803 CM G A Missense p.V226I c.676G>A 11 119206508 CM G A Nonsense p.W178* c.533G>A 11 119206365 UCEC G A Synonymous p.K388K c.1164G>A 11 119206996 OV G C Missense p.A108P c.322G>C 11 119206154 LUSC G C Missense p.Q296H c.888G>C 11 119206720 LUSC G T Missense p.V390L c.1168G>T 11 119207000 PRAD T A Synonymous p.A145A c.435T>A 11 119206267 GBM T C Missense p.I114T c.341T>C 11 119206173 STAD