Disease associated variation - ClinVar Allele ID Type Name RS#dbSNP Phenotype IDs Chromosome Start Stop Reference Alternate 249205 deletion KLHL15, 22.5-KB DEL -1 MedGen:CN238512,OMIM:300982 na -1 -1 na na 249206 deletion KLHL15, 1-BP DEL -1 MedGen:CN238512,OMIM:300982 na -1 -1 na na

Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug X 24039777 rs6526366 C T rs6526366 3.53E-04 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 T intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs5925972 X 24007151 24007151 intronic 0.4834 0.315693353928368 GWAS of prostate cancer rs7064691 X 24018058 24018058 intronic 0.334712 0.47532871716011804 GWAS of prostate cancer rs10521917 X 24012381 24012381 intronic 0.311335 0.506772053578865 GWAS of prostate cancer rs6526366 X 24039777 24039777 intronic 0.271376 0.566428563192312

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000174010.9 KLHL15 300980