PTM - CPLM Gene Name UniProt ID Type Position Code TTC3; DCRR1; RNF105; TPRD P53804 Acetylation 1596 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 470 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 488 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1153 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 123 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1530 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 799 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 804 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 465 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 397 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 124 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1097 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 140 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 629 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 348 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 237 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 244 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 337 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 345 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 967 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1190 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1196 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 1204 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 53 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 601 K TTC3; DCRR1; RNF105; TPRD P53804 Ubiquitination 360 K

PTM - dbPAF Gene Name UniProt ID Position Type Species TTC3; DCRR1; RNF105; TPRD P53804 1009 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1189 T Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1244 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1278 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1288 Y Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1581 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1584 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1651 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1695 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1730 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1733 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1816 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1819 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1923 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1924 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1927 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1929 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1935 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 1938 T Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 2003 T Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 2006 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 221 T Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 223 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 268 Y Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 310 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 376 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 378 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 429 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 456 S Homo sapiens(Human) TTC3; DCRR1; RNF105; TPRD P53804 459 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P53804 K1596-ac Acetylation QKNDGKEkEHELHLD P53804 K1703-ac Acetylation NVTKEIEkAkSQFEE P53804 K1705-ac Acetylation TKEIEkAkSQFEEQI P53804 T221-p Phosphorylation NLLEELKtQsCMDCI P53804 S223-p Phosphorylation LEELKtQsCMDCIEE P53804 Y268-p Phosphorylation RPENYLLyGNRALCF P53804 S310-p Phosphorylation YRYCDALsMLGEYDW P53804 S376-p Phosphorylation NRAYTPRsLsAPIFT P53804 S378-p Phosphorylation AYTPRsLsAPIFTTS P53804 S429-p Phosphorylation CDCHPEFsPPSSQPP P53804 T459-p Phosphorylation FSSSSPLtLPADLKN P53804 S1009-p Phosphorylation TVLRKQDsGEAPFSS P53804 T1189-p Phosphorylation RKKKNIKtKVEEISK P53804 S1244-p Phosphorylation PKPVSANsPKPACED P53804 S1278-p Phosphorylation PKGVSSNsPKPGSED P53804 Y1288-p Phosphorylation PGSEDANyKRVSCNS P53804 S1581-p Phosphorylation KKKIKKVsNAsEMYT P53804 S1584-p Phosphorylation IKKVsNAsEMYTQKN P53804 S1651-p Phosphorylation VLENWKEsEVYKLQI P53804 S1695-p Phosphorylation RSWELFLsNVTKEIE P53804 S1730-p Phosphorylation ELSKVQIsELsFPAC P53804 S1733-p Phosphorylation KVQIsELsFPACNTV P53804 S1819-p Phosphorylation QAALSERsPVADRKQ P53804 S1927-p Phosphorylation VTRSSQGsPSVVVAP P53804 S1935-p Phosphorylation PSVVVAPsPKTKGQK P53804 T2003-p Phosphorylation CQGRDLLtEESPSGR P53804 K348-ub Ubiquitination QQHVKLQkQIEDLQG P53804 K470-ub Ubiquitination DLKNILEkQFSKSSR

PTM - dbPTM UniProt ID Position Code Type Resources References P53804 378 S Phosphorylation Swiss-Prot 1010711 20059950 P53804 1923 S Phosphorylation PhosphoELM.10011 17081983 P53804 1924 S Phosphorylation PhosphoELM.10011 17081983 P53804 1935 S Phosphorylation PhosphoELM.10011 17081983 P53804 1938 T Phosphorylation PhosphoELM.10011 17081983 P53804 470 K Ubiquitylation Phosphositeplus.1010730 21890473 P53804 1596 K Acetylation Phosphositeplus.1010730 20167786 P53804 378 S Phosphorylation Phosphositeplus.1010730 20059950 P53804 1288 Y Phosphorylation Phosphositeplus.1010730 17360941 P53804 1923 S Phosphorylation HPRD 9.0 17081983 P53804 1924 S Phosphorylation HPRD 9.0 17081983 P53804 1935 S Phosphorylation HPRD 9.0 17081983 P53804 1938 T Phosphorylation HPRD 9.0 17081983 P53804 1923 S Phosphorylation SysPTM 1.1 17081983 P53804 1924 S Phosphorylation SysPTM 1.1 17081983 P53804 1935 S Phosphorylation SysPTM 1.1 17081983 P53804 1938 T Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References TTC3 1923 S Phosphorylation 17081983 TTC3 1924 S Phosphorylation 17081983 TTC3 1935 S Phosphorylation 17081983 TTC3 1938 T Phosphorylation 17081983

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P53804 1938 T 17081983 HTP Phosphorylation P53804 1923 S 17081983 HTP Phosphorylation P53804 1935 S 17081983 HTP Phosphorylation P53804 1924 S 17081983 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P53804 378 Phosphoserine; by PKB/AKT2 20059950

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type TTC3 IPI00023977 S 1923 ATPVTRpSSQGSPS phosphorylation TTC3 IPI00023977 S 1924 TPVTRSpSQGSPSV phosphorylation TTC3 IPI00023977 S 1935 SVVVAPpSPKTKGQ phosphorylation TTC3 IPI00023977 T 1938 VAPSPKpTKGQKAE phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7267 113118 - K Ubiquitination 21139048 7267 113118 - K Ubiquitination 21890473

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID TTC3 Homo sapiens (Human) 452 "452,LKNILEKQFSKSS" 452:21890473 TTC3 Homo sapiens (Human) 470 "470,LKNILEKQFSKSS" 470:21890473 TTC3 Homo sapiens (Human) 470 "470,LKNILEKQFSKSS" 470:21890473 TTC3 Homo sapiens (Human) 237 "237,LKNILEKQFSKSS" 237:21890473 TTC3 Homo sapiens (Human) 160 "160,LKNILEKQFSKSS" 160:21890473 TTC3 Homo sapiens (Human) 452 "452,LKNILEKQFSKSS" 452:21890473 TTC3 Homo sapiens (Human) 470 "470,LKNILEKQFSKSS" 470:21890473