DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome CCIN 5'UTR 1bca0efc0d NM_005893 chr9:36155990-36159499:+

DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence CCIN ATTTA 112-1878 1921-1925

DNA & RNA Element - miRTarBase Target Gene (Entrez ID) miRTarBase ID miRNA Species (miRNA) Target Gene Species (Target Gene) Experiments Support Type References (PMID) MIRT042434 hsa-miR-424-5p Homo sapiens CCIN 881 Homo sapiens CLASH Functional MTI (Weak) 23622248

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004493 hsa-miR-20a* 881 CCIN gaAAUUCAC-----GAGU-A-UUACGUca ||||||| | | | |||||| uuUUAAGUGGGAGAAUAAGUAAAUGCAuu 3 21 4 32 [hg19:9:36171270-36171298:+] 0.8319 121 0 -10.69 -0.1268 MIMAT0004499 hsa-miR-26a-1* 881 CCIN gcACGUUCAUUGGUUCUUAUcc | :||||:: :|||||| auUUUAAGUGG--GAGAAUAag 3 21 3 22 [hg19:9:36171269-36171288:+] 0.8319 133 0 -11.74 -0.1490 MIMAT0009198 hsa-miR-224* 881 CCIN acaucAGUGAUCCCGUGGUAAAa |:|:|| ||| |||| augcaUUAUUA-UUCACGAUUUa 2 19 26 47 [hg19:9:36171292-36171313:+] 0.8319 120 0 -8.05 -0.1255 MIMAT0004613 hsa-miR-188-3p 881 CCIN acguuUGGGACGUACACCCUc || :| :| |||||| -----ACAUUUUAAGUGGGAg 2 17 1 16 [hg19:9:36171267-36171282:+] 0.8319 124 6 -17.04 -0.3753 MIMAT0004680 hsa-miR-130b* 881 CCIN caucACGUUG-UCCCUUUCUCa | :||: || ||||||| acgaUUUAAUGAGAGAAAGAGa 2 18 40 61 [hg19:9:36171306-36171327:+] 0.7518 152 7 -11.62 -1.2147 MIMAT0004681 hsa-miR-26a-2* 881 CCIN cuuuGUUCAUUAGUUCUUAUcc :||||:: :|||||| auuuUAAGUGG--GAGAAUAag 3 19 3 22 [hg19:9:36171269-36171288:+] 0.8319 131 0 -12.16 -0.1490 MIMAT0004780 hsa-miR-532-3p 881 CCIN acguucggaacccaCACCCUCc ||||||| -----acauuuuaaGUGGGAGa 2 9 1 17 [hg19:9:36171267-36171283:+] 0.8319 140 7 -13.24 -1.2975 MIMAT0003252 hsa-miR-586 881 CCIN ccuggaUUUUUAUGUUACGUAu | ||:|| ||||||| gggagaAUAAGUA-AAUGCAUu 2 17 12 32 [hg19:9:36171278-36171298:+] 0.8319 154 7 -12.49 -1.0132 MIMAT0003298 hsa-miR-629* 881 CCIN cgacccGAAUGCAACCCUCUUg :||| | |||||||| --acauUUUAAG-UGGGAGAAu 2 17 1 19 [hg19:9:36171267-36171285:+] 0.8319 154 7 -15.97 -1.1137 MIMAT0003299 hsa-miR-630 881 CCIN uggAAGGGACCAUGUCUUAUga ||:: | : |||||| acaUUUUAAGUGGGAGAAUAag 3 20 1 22 [hg19:9:36171267-36171288:+] 0.8319 123 0 -10.26 -0.1519 MIMAT0003312 hsa-miR-642 881 CCIN guucugUGUAAACCUCUCCCUg |||||| || |||| ------ACAUUUUAAGUGGGAg 2 17 1 16 [hg19:9:36171267-36171282:+] 0.8319 132 0 -12.69 -0.1121 MIMAT0004985 hsa-miR-942 881 CCIN guguaccggUUUUGUCUCUUCu :|:| |||||:| auuuaaugaGAGAAAGAGAGG- 2 14 43 63 [hg19:9:36171309-36171329:+] 0.7518 133 0 -11.27 -0.1397 MIMAT0005908 hsa-miR-1257 881 CCIN ccagucuugGGUAGUAAGUGa ::||:|||||| guaaaugcaUUAUUAUUCACg 2 13 22 42 [hg19:9:36171288-36171308:+] 0.8319 136 6 -11.29 -0.4727 MIMAT0005911 hsa-miR-1260 881 CCIN accaccgucucCACCCUa |||||| --acauuuuaaGUGGGAg 2 8 1 16 [hg19:9:36171267-36171282:+] 0.8319 120 6 -9.98 -0.3843 MIMAT0009454 hsa-miR-1979 881 CCIN aucaguucacuucgUCACCCUc ||||||| ------acauuuuaAGUGGGAg 2 9 1 16 [hg19:9:36171267-36171282:+] 0.8319 140 7 -16.14 -1.1557 MIMAT0011161 hsa-miR-2116* 881 CCIN cccucaaGAACCGUACCCUCc :|| :|||||| ----acaUUUUAAGUGGGAGa 2 15 1 17 [hg19:9:36171267-36171283:+] 0.8319 126 6 -11.77 -0.5759 MIMAT0011162 hsa-miR-2117 881 CCIN gacaggaaccguUUCUCUUgu :|||||| ucacgauuuaauGAGAGAAag 3 10 38 58 [hg19:9:36171304-36171324:+] 0.7518 121 0 -6.78 -0.1383 MIMAT0015041 hsa-miR-1260b 881 CCIN uaccaccgucacCACCCUa |||||| ---acauuuuaaGUGGGAg 2 8 1 16 [hg19:9:36171267-36171282:+] 0.8319 120 6 -9.98 -0.3843 MIMAT0015063 hsa-miR-3183 881 CCIN aggcucgcugaggcUCUCUCCg ||||||| auuuaaugagagaaAGAGAGG- 2 9 43 63 [hg19:9:36171309-36171329:+] 0.7518 140 7 -17.35 -1.2331 MIMAT0016916 hsa-miR-4286 881 CCIN ccaugguccUCACCCca |||||| -acauuuuaAGUGGGag 3 9 1 16 [hg19:9:36171267-36171282:+] 0.8319 120 0 -10.67 -0.3270 MIMAT0000091 hsa-miR-33a 881 CCIN acguuacguugaugUUACGUg |||||| ugggagaauaaguaAAUGCAu 2 8 11 31 [hg19:9:36171277-36171297:+] 0.8319 120 6 -9.32 -0.3486 MIMAT0000451 hsa-miR-150 881 CCIN gugaccauguucccaACCCUCu |||||| -----acauuuuaagUGGGAGa 2 8 1 17 [hg19:9:36171267-36171283:+] 0.8319 120 6 -16.53 -0.5868 MIMAT0000646 hsa-miR-155 881 CCIN uggggauagugcuaauCGUAAUu |||||| gggagaauaaguaaauGCAUUAu 2 8 12 34 [hg19:9:36171278-36171300:+] 0.8319 120 6 -4.07 -0.1101 MIMAT0003301 hsa-miR-33b 881 CCIN cguuacguugucgUUACGUg |||||| gggagaauaaguaAAUGCAu 2 8 12 31 [hg19:9:36171278-36171297:+] 0.8319 120 6 -9.95 -0.3486

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G046268 CCIN Homo sapiens 881

DNA & RNA Element - TargetScan Gene Name UTR Region Start UTR Region End AIR Total Normalized 3P-seq-tags & Pseudocounts Strand hg19_chromosome Genome Start Genome End CCIN 1 63 100 5.01 + chr9 36171266 36171329 CCIN 64 65 0.2 5.01 + chr9 36171329 36171331

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile CCIN hsa-miR-1979 beg:6 end:17 pic:3' ATCAGTTCACTTCGTCACCCTC 5'& |||||||| &5' --------------AGTGGGAG 3' CCIN hsa-miR-629star beg:2 end:20 pic:3' CGACCCGAATGCAACCCTCTTG 5'& .||| ||||||||. &5' ------TTTAAG-TGGGAGAAT 3' CCIN hsa-miR-1260 beg:7 end:16 pic:3' ACCACCGTCTCCACCCTA 5'& |||||| &5' -----------GTGGGA- 3' CCIN hsa-miR-1260b beg:7 end:16 pic:3' TACCACCGTCACCACCCTA 5'& |||||| &5' ------------GTGGGA- 3' CCIN hsa-miR-454 beg:15 end:34 pic:3' TGGGATATTCGTTATAACGTGAT 5'& |||||.|| ||||.|| &5' -----ATAAGTAAA--TGCATTA 3' CCIN hsa-miR-586 beg:11 end:31 pic:3' CCTGGATTTTTATG---TTACGTAT 5'& .|.|||| ||||||| &5' ------GAGAATAAGTAAATGCAT- 3'

DNA & RNA Element - miRNAMap Gene Name Mature miRNA Target Start Target End miRNA 3-5 Alignment Target 5-3 CCIN hsa-miR-150 1 19 GUGACCAUGUUCCCA--ACCCUCU- ||| ||||||| -------ACAUUUUAAGUGGGAGAA CCIN hsa-miR-629 4 21 CGACCCGAAUGCAACCCUCUUG- :||| ||||||||: -----UUUUAAG-UGGGAGAAUA CCIN hsa-miR-629 1 19 cgacccgAAUGCAACCCUCUUg ||| | |||||||| --acattTTAAG-TGGGAGAAt

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region CCIN High_conserved miR-7/7ab chr9:36170602 8-mer 53 CDS CCIN High_conserved miR-133abc chr9:36170570 7-mer-m8 69 CDS CCIN High_conserved miR-133abc chr9:36171165 8-mer 60 CDS CCIN High_conserved miR-93/93a/105/106a/291a-3p/294/295/302abcde/372/373/428/519a/520be/520acd-3p/1378/1420ac chr9:36170460 8-mer 36 CDS CCIN High_conserved miR-96/507/1271 chr9:36169895 7-mer-m8 33 CDS CCIN High_conserved miR-138/138ab chr9:36170853 8-mer 11 CDS CCIN High_conserved miR-143/1721/4770 chr9:36169673 7-mer-m8 51 CDS CCIN High_conserved miR-150/5127 chr9:36171283 7-mer-A1 56 3pUTR CCIN High_conserved miR-15abc/16/16abc/195/322/424/497/1907 chr9:36169473 7-mer-m8 33 5pUTR CCIN High_conserved let-7/98/4458/4500 chr9:36169911 7-mer-m8 58 CDS CCIN High_conserved miR-193/193b/193a-3p chr9:36169995 7-mer-m8 49 CDS CCIN High_conserved miR-193/193b/193a-3p chr9:36170377 7-mer-m8 16 CDS CCIN High_conserved miR-199ab-5p chr9:36170792 7-mer-A1 16 CDS CCIN High_conserved miR-199ab-5p chr9:36171211 7-mer-A1 47 CDS CCIN High_conserved miR-19ab chr9:36169624 8-mer 44 CDS CCIN High_conserved miR-200bc/429/548a chr9:36169831 7-mer-m8 53 CDS CCIN High_conserved miR-203 chr9:36169834 7-mer-A1 53 CDS CCIN High_conserved miR-203 chr9:36170149 7-mer-A1 42 CDS CCIN High_conserved miR-214/761/3619-5p chr9:36169471 7-mer-m8 42 5pUTR CCIN High_conserved miR-214/761/3619-5p chr9:36169474 7-mer-A1 31 5pUTR CCIN High_conserved miR-214/761/3619-5p chr9:36170307 7-mer-m8 58 CDS CCIN High_conserved miR-214/761/3619-5p chr9:36171227 7-mer-m8 60 CDS CCIN High_conserved miR-24/24ab/24-3p chr9:36169735 7-mer-m8 36 CDS CCIN High_conserved miR-31 chr9:36171023 7-mer-m8 51 CDS CCIN High_conserved miR-103a/107/107ab chr9:36169546 7-mer-A1 56 CDS CCIN High_conserved miR-338/338-3p chr9:36171160 7-mer-A1 53 CDS CCIN High_conserved miR-34ac/34bc-5p/449abc/449c-5p chr9:36171108 8-mer 11 CDS CCIN High_conserved miR-383 chr9:36169433 7-mer-m8 4 5pUTR CCIN Medium_conserved miR-544/544ab/544-3p chr9:36169550 7-mer-m8 53 CDS CCIN Medium_conserved miR-544/544ab/544-3p chr9:36170981 7-mer-m8 62 CDS CCIN Medium_conserved miR-653 chr9:36169837 7-mer-m8 56 CDS CCIN Medium_conserved miR-875-5p chr9:36169945 7-mer-m8 38 CDS CCIN Medium_conserved miR-136 chr9:36170232 7-mer-A1 47 CDS CCIN Medium_conserved miR-185/882/3473/4306/4644 chr9:36169460 7-mer-A1 7 5pUTR CCIN Medium_conserved miR-197 chr9:36169786 7-mer-m8 42 CDS CCIN Medium_conserved miR-197 chr9:36170806 7-mer-A1 56 CDS CCIN Medium_conserved miR-290-5p/292-5p/371-5p/293 chr9:36169932 7-mer-m8 40 CDS CCIN Medium_conserved miR-296-3p chr9:36170255 7-mer-m8 22 CDS CCIN Medium_conserved miR-370 chr9:36170287 7-mer-A1 60 CDS CCIN Medium_conserved miR-378/422a/378bcdefhi chr9:36171120 7-mer-A1 53 CDS CCIN Medium_conserved miR-379/1193-5p/3529 chr9:36170314 8-mer 11 CDS CCIN Medium_conserved miR-382 chr9:36169979 7-mer-m8 58 CDS CCIN Medium_conserved miR-410/344de/344b-1-3p chr9:36170816 7-mer-m8 13 CDS CCIN Medium_conserved miR-431 chr9:36170999 7-mer-m8 40 CDS CCIN Medium_conserved miR-485-5p/1698/1703/1962 chr9:36169668 7-mer-A1 47 CDS CCIN Medium_conserved miR-491-5p chr9:36169654 7-mer-m8 11 CDS CCIN Medium_conserved miR-494 chr9:36169483 7-mer-A1 13 5pUTR

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score CCIN RAID00470675 hsa-miR-33a-5p miRNA MIMAT0000091 CCIN mRNA 881 Prediction 0.1828 CCIN RAID02189585 hsa-miR-424-5p miRNA MIMAT0001341 CCIN mRNA 881 CLASH 0.5483 CCIN RAID02727058 hsa-miR-150-5p miRNA MIMAT0000451 CCIN mRNA 881 Prediction 0.1828 CCIN RAID03211325 hsa-miR-155-5p miRNA MIMAT0000646 CCIN mRNA 881 Prediction 0.1828 CCIN RAID04061321 hsa-miR-33b-5p miRNA MIMAT0003301 CCIN mRNA 881 Prediction 0.1828