Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 9 84289975 rs3894391 G A rs3894391 9.44E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_drug 9 84201594 rs2796460 C A rs2796460 1.52E-06 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 9 84201594 rs2796460 C A rs2796460 4.69E-04 Aortic root size HPOID:0002597 DOID:1287 A intron GWASdb_trait 9 84210209 rs7860431 C T rs7860431 3.69E-05 Acute lung injury HPOID:0002088 DOID:850 T intron GWASdb_trait 9 84212422 rs1539377 A T rs1539377 5.26E-06 Blood Pressure and Arterial Stiffness HPOID:0011025|HPOID:0002634 DOID:2349|DOID:10763 T intron GWASdb_trait 9 84213160 rs2777777 C T rs2777777 9.00E-06 Visceral adipose tissue adjusted for BMI HPOID:0009124 DOID:9970 T intron GWASdb_trait 9 84222618 rs815847 G A rs815847 3.00E-06 Visceral fat HPOID:0009124 DOID:9970 A intron GWASdb_trait 9 84222905 rs815846 G A rs815846 4.89E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 9 84254819 rs10867787 A G rs10867787 3.09E-05 Waist Circumference HPOID:0001513 DOID:9970 A intron GWASdb_trait 9 84256984 rs12551040 A G rs12551040 6.38E-05 Body Mass Index HPOID:0001507 DOID:9970 G intron GWASdb_trait 9 84262437 rs10780526 A T rs10780526 1.23E-05 Serum metabolites HPOID:0011111 NA A intron GWASdb_trait 9 84262485 rs4877669 A G rs4877669 9.86E-05 Waist-Hip Ratio HPOID:0001513 DOID:9970 G intron GWASdb_trait 9 84262687 rs10867791 T C rs10867791 3.89E-05 Serum metabolites HPOID:0011111 NA C intron GWASdb_trait 9 84262687 rs10867791 T C rs10867791 2.90E-06 Urinary metabolites HPOID:0000079 DOID:557 C intron GWASdb_trait 9 84268878 rs2796447 A G rs2796447 5.24E-05 Body Mass Index HPOID:0001507 DOID:9970 G intron GWASdb_trait 9 84288353 rs2591 C T rs2591 5.47E-04 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000196781.14 TLE1 600189