PTM - CPLM Gene Name UniProt ID Type Position Code TLE1 Q04724 Acetylation 281 K

PTM - dbPAF Gene Name UniProt ID Position Type Species TLE1 Q04724 239 S Homo sapiens(Human) TLE1 Q04724 244 S Homo sapiens(Human) TLE1 Q04724 253 S Homo sapiens(Human) TLE1 Q04724 258 S Homo sapiens(Human) TLE1 Q04724 259 S Homo sapiens(Human) TLE1 Q04724 263 S Homo sapiens(Human) TLE1 Q04724 267 S Homo sapiens(Human) TLE1 Q04724 284 S Homo sapiens(Human) TLE1 Q04724 285 S Homo sapiens(Human) TLE1 Q04724 286 S Homo sapiens(Human) TLE1 Q04724 289 S Homo sapiens(Human) TLE1 Q04724 290 T Homo sapiens(Human) TLE1 Q04724 292 S Homo sapiens(Human) TLE1 Q04724 311 S Homo sapiens(Human) TLE1 Q04724 312 T Homo sapiens(Human) TLE1 Q04724 318 S Homo sapiens(Human) TLE1 Q04724 319 T Homo sapiens(Human) TLE1 Q04724 69 Y Homo sapiens(Human) TLE1 Q04724 692 Y Homo sapiens(Human) TLE1 Q04724 699 S Homo sapiens(Human) TLE1 Q04724 703 S Homo sapiens(Human) TLE1 Q04724 739 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q04724 K281-ac Acetylation DKNRLLKkDAsssPA Q04724 K718-ac Acetylation KWFVSTGkDNLLNAW Q04724 R6-m1 Methylation __MFPQSrHPTPHQA Q04724 R338-m1 Methylation TSATPGLrPGLGkPP Q04724 K343-m1 Methylation GLrPGLGkPPAIDPL Q04724 R359-m1 Methylation NQAAAGLrTPLAVPG Q04724 R641-m1 Methylation GGLDNTVrSWDLREG Q04724 S235-p Phosphorylation KVDDKDSsHYDsDGD Q04724 S239-p Phosphorylation KDSsHYDsDGDKsDD Q04724 S244-p Phosphorylation YDsDGDKsDDNLVVD Q04724 S253-p Phosphorylation DNLVVDVsNEDPSsP Q04724 S259-p Phosphorylation VsNEDPSsPRAsPAH Q04724 S263-p Phosphorylation DPSsPRAsPAHsPRE Q04724 S267-p Phosphorylation PRAsPAHsPRENGID Q04724 S284-p Phosphorylation RLLKkDAsssPAstA Q04724 S285-p Phosphorylation LLKkDAsssPAstAs Q04724 S286-p Phosphorylation LKkDAsssPAstAsS Q04724 S289-p Phosphorylation DAsssPAstAsSASS Q04724 T290-p Phosphorylation AsssPAstAsSASST Q04724 S292-p Phosphorylation ssPAstAsSASSTSL Q04724 S305-p Phosphorylation SLKSKEMsLHEKASt Q04724 T312-p Phosphorylation sLHEKAStPVLKSSt Q04724 T319-p Phosphorylation tPVLKSStPTPRSDM Q04724 Y692-p Phosphorylation HVNKPDKyQLHLHEs Q04724 S699-p Phosphorylation yQLHLHEsCVLsLKF Q04724 S703-p Phosphorylation LHEsCVLsLKFAYCG Q04724 K762-sm Sumoylation VTGSGDKkATVYEVI Q04724 K30-ub Ubiquitination PESLDRIkEEFQFLQ Q04724 K718-ub Ubiquitination KWFVSTGkDNLLNAW

PTM - dbPTM UniProt ID Position Code Type Resources References Q04724 286 S Phosphorylation Swiss-Prot 1010711 19413330 Q04724 239 S Phosphorylation PhosphoELM.10011 15367661 Q04724 718 K Ubiquitylation Phosphositeplus.1010730 21890473 Q04724 281 K Acetylation Phosphositeplus.1010730 20167786 Q04724 239 S Phosphorylation Phosphositeplus.1010730 15367661;21406692;22354967 Q04724 244 S Phosphorylation Phosphositeplus.1010730 20164059;21406692 Q04724 253 S Phosphorylation Phosphositeplus.1010730 22354967 Q04724 259 S Phosphorylation Phosphositeplus.1010730 21406692 Q04724 263 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q04724 267 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q04724 285 S Phosphorylation Phosphositeplus.1010730 19664995 Q04724 286 S Phosphorylation Phosphositeplus.1010730 19664994;19664995;19690332;19956621;21406692 Q04724 285 S Phosphorylation HPRD 9.0 19664995 Q04724 286 S Phosphorylation HPRD 9.0 19413330,19664995,19664994

PTM - HPRD Symbol Position Code Type References TLE1 285 S Phosphorylation 19664995 TLE1 286 S Phosphorylation 19413330,19664995,19664994

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q04724 239 S 15367661 CK2_alpha LTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q04724 239 Phosphoserine 21406692 Q04724 286 Phosphoserine 21406692

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 7088 112943 - K Ubiquitination 21890473 7088 112943 - K Ubiquitination 22053931

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID TLE1 Homo sapiens (Human) 718 "718,WFVSTGKDNLLNA" 718:21890473 TLE1 Homo sapiens (Human) 718 "718,WFVSTGKDNLLNA" 718:21890473 TLE1 Homo sapiens (Human) 516 "516,WFVSTGKDNLLNA" 516:21890473 TLE1 Homo sapiens (Human) 718 "718,WFVSTGKDNLLNA" 718:21890473 TLE1 Homo sapiens (Human) 718 "718,WFVSTGKDNLLNA" 718:21890473 TLE1 Homo sapiens (Human) 718 "718,WFVSTGKDNLLNA" 718:21890473