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GP G G G GP G G GP G G G G GP G G GP GP G G G G WWP2 LDLRAD4 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP P G WWP2 UBE2K 22496338 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 FAM189A2 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP GP G GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CUL1 21145461 biogrid exp GP G G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 WIPF1 25416956,21516116 biogrid,mint,intact exp G G G G G G G G G G G G GP GP G G G G G G GP G G G G G G G WWP2 NDFIP1 26186194 biogrid exp GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 NXF1 22658674 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 VASP 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 FAM168A 26186194 biogrid exp G G G G G GP G GP G G G G G G G G GP G G G G G G GP G G G GP G WWP2 FBXL18 25416956 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 PTPN14 22948661 biogrid exp GP GP G GP G GP GP G GP P GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 DGCR2 26186194 biogrid exp G G G G G G G G G G G G GP G G G G G GP G G G G G G G G G G WWP2 SCN5A 15548568 biogrid exp G G G G G G G G G G G G G G G G G G G WWP2 ANKRD44 25416956 biogrid,intact exp G GP G G G GP G GP GP G G G GP GP G G GP G GP G GP G G G G GP P G WWP2 LGALS9B 25416956 biogrid,intact exp P P P P P P P P P WWP2 SF1 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SEC24D 21516116 biogrid,mint,intact exp GP GP G G P G GP GP GP GP GP GP G GP P G GP G G GP GP P GP G GP GP G WWP2 PTCH1 25092867 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SNRPC 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 ATP6AP2 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 HNRNPUL1 25416956,21516116 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PABPC1 25266661 biogrid exp GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 RNF11 15231748 hprd,biogrid,i2d,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 EWSR1 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 S1PR1 21555855 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP G GP P G WWP2 TMEM132A 26496610 biogrid,intact exp G GP G G G GP G GP GP G GP P G G G GP GP G G G G G GP GP GP G GP GP G WWP2 SCNN1B 11244092,12167593 hprd,biogrid exp GP GP G G P G GP G GP GP GP P G P P GP GP GP GP GP G GP P G WWP2 SPG20 19307600 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 AMOTL1 26186194 biogrid exp G G G G G GP G GP GP G G G G G G G GP G G G GP G G G G G G GP G WWP2 FBXL15 21572392 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G WWP2 NTRK1 25921289 biogrid exp P P P G P P P P P P P P P P P P P P WWP2 VPS11 22939629 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 NDFIP2 20522958,15252135 hprd,biogrid exp GP G G G G GP G G GP G GP G GP GP G GP GP G GP G G G GP GP GP G GP GP G WWP2 PDLIM7 25416956,16189514,21516116 hprd,biogrid,mint,intact exp G GP G G P G GP G G GP G GP G G G GP G GP G GP G G GP G G G GP G WWP2 PAIP1 25266661 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 CPSF6 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 DIDO1 16189514 hprd,biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 RUSC1 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 MKNK2 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBP1 21956701 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 WWP2 17719543,21258410,17996703,23938591,22496338 biogrid,i2d,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 ADARB1 doi:10.1038/emboj.2011.303,21847096 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G P G GP GP P GP GP G GP P G WWP2 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G WWP2 EIF3A 25266661 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 RASA1 9169421 hprd,bci exp GP G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G WWP2 AMOT 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G WWP2 FIP1L1 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP G GP GP WWP2 NOTCH3 25356737 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CEP131 21956701 biogrid exp P P P G G P P G P GP G WWP2 TNK2 19144635 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G VPS37C WWP2 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SCAMP3 19158374 hprd,biogrid exp G G G G G GP G GP G G GP G GP GP G G GP G GP G G G G GP G G GP GP G WWP2 ARRDC4 23236378 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 TMEM255A 26186194 biogrid exp G P G GP G P GP G P P G P GP G P G P P P P GP P WWP2 TP53BP2 9169421 hprd,bci exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 DVL3 19888210 i2d exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 ARRDC3 23236378 biogrid exp, ortho G G G G G GP G G G G GP GP G G G GP GP G G G G G G GP GP G GP GP G WWP2 IL6R 9169421 hprd exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 EGR2 19651900 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G WWP2 TRAF4 25416956,21516116 biogrid,mint,intact exp, ortho G GP G GP G P GP G GP GP GP G G GP GP G GP G GP G GP P GP G GP GP G WWP2 ARRDC1 21191027,21516116,26186194,22315426,23236378 biogrid exp, ortho G GP G G G GP G GP GP G GP GP G G G GP GP G GP G GP G G GP GP G GP GP G WWP2 UBC 19343052,23644597,23938591,22496338 biogrid,mint,intact exp, ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SFTPC 19366705 biogrid exp, ortho G G G G G G G G G G G G GP G G G G G G G G G G G G G G G G WWP2 IL2RG 9169421 hprd,bci exp, ortho G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G WWP2 DAG1 9169421 hprd,bci exp, ortho G G G G G GP G GP GP G GP G GP G G G GP G GP G GP GP G GP G G GP GP G WWP2 EZH2 24457600 innatedb,biogrid exp, ortho GP P G G GP P GP G GP G P P P GP G GP GP WWP2 DVL2 19888210,20007894 i2d exp, ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CLCN5 9169421 hprd exp, ortho G G G G GP G G G G GP G GP GP GP GP G GP G GP G G GP GP G GP P G WWP2 SMAD1 15761153, 25402006 i2d exp, ortho, pred G G G G G G G G GP G G G G G G G G G G G G G G G G G G GP G WWP2 SCNN1G 12167593, 21836163 hprd,biogrid exp, ortho, pred G G G G G G WWP2 SMAD2 21258410,15761153,18729074, 25402006 innatedb,biogrid,i2d,intact exp, ortho, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 TFAP2A 9169421, 21836163 hprd exp, ortho, pred GP G G G G G G G G GP G G G G G G G G GP G G G G G G G WWP2 SCNN1A 12167593, 21836163 hprd,biogrid exp, ortho, pred GP GP P P GP GP P GP GP G GP P GP G P GP GP P GP GP GP G WWP2 POU5F1 22387393,19274063, 21836163 biogrid,intact exp, ortho, pred P P P P P P P P P P P P P P P P P P P WWP2 SMAD3 21258410,21516116,23938591,15761153,18729074, 25402006, 23023127 innatedb,biogrid,i2d,intact exp, ortho, pred GP GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G WWP2 PTEN 22427670,21532586,24063548,15717329, 21836163 biogrid exp, ortho, pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP G GP GP G WWP2 UBE2L3 17719543,17996703,19274063, 25402006, 16082366 biogrid exp, ortho, pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP G GP GP G WWP2 CDC34 22496338, 23023127, 16082366 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2D3 23644597,25266661, 23023127 biogrid exp, pred GP G G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP G GP G G GP GP G WWP2 ATN1 9647693,16713569, 25402006, 21836163 hprd,biogrid,i2d,mint,intact,bci exp, pred GP GP G G G GP G GP GP G GP GP G G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2E3 22496338, 23023127, 21836163, 16082366 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G WWP2 SMAD7 21258410,15761153,22773947, 23023127 biogrid,i2d,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP P G WWP2 TGFBR1 15761153, 25402006, 23023127 i2d exp, pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G G G G G GP G GP G G WWP2 PSMD10 22387393, 23023127 biogrid exp, pred GP G G G G GP G G GP G G G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 UBE2G1 22939629, 23023127, 16082366 biogrid exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2E1 19274063, 23023127, 21836163, 16082366 biogrid exp, pred GP GP G G G GP G G GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G WWP2 SMAD6 24850914, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G WWP2 FBXO11 26186194, 21836163 biogrid exp, pred G G G G G GP G G G G G GP GP G G GP GP G G G GP G G G GP G G G G WWP2 USP7 16713569, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2D2 22496338, 21836163, 16082366 biogrid exp, pred GP G G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP G GP G G GP GP G WWP2 SMARCC1 ortho GP G G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G WWP2 GSC ortho WWP2 SOX2 ortho P P G GP G P GP G P P GP P GP GP P G P GP P GP GP GP G WWP2 POLR2A 21836163 ortho, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PAK2 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP G G WWP2 PRKCD 23023127 pred GP GP G G G GP G GP GP GP P GP GP G GP GP G GP GP GP GP P GP G GP GP G WWP2 THOC3 23023127 pred P P P P P P P P P P P P P P P P P P P WWP2 USP19 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 NELL2 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 TRAF7 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G WWP2 THOC7 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 TRIM23 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 MDM4 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 THOC5 23023127 pred G GP G G G GP G G GP G GP G GP G G GP GP G G G GP GP G GP GP G GP G G WWP2 MAP2K6 23023127 pred GP G G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP G G WWP2 SMURF1 25402006, 23023127, 21836163 pred G GP G G G GP G G GP G GP G GP G G G GP G G G GP G G G G G G GP G WWP2 PRKAG2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 AKAP1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PCBP2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2I 23023127, 16082366 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 CBFA2T2 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CD80 23023127 pred G G G G G GP G G G G G G G GP G G GP G G G GP G G G G G G G G WWP2 CNTN1 25402006 pred G G G GP G GP G G G G G G GP GP G G G G G G GP G GP G G WWP2 BMPR1A 23023127 pred GP GP G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PCGF6 23023127 pred G G G G G G G G G G GP GP G G G G G G G G G G G G G G G G G WWP2 SUMO2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 F9 23023127 pred G G G G G G G WWP2 SKIL 25402006, 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G GP GP GP GP GP G GP GP G WWP2 TMPRSS4 23023127 pred P P P GP P P P P GP P GP P P GP P GP GP P WWP2 CREBBP 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 STXBP4 25402006, 23023127 pred P GP G G P P P GP P P P G P P G GP G GP GP P P GP P P G WWP2 SENP1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 RPS27A 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SRPX2 23023127 pred GP GP P G GP GP P P GP GP G P P G P GP P P P GP P P G WWP2 MECOM 25402006 pred GP P P G GP GP G GP P GP P G GP P G GP G GP GP GP GP GP G GP GP G WWP2 AKT2 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 MAPK4 23023127 pred P P P P P P GP P P P P GP P P P P P P P WWP2 PSG4 23023127 pred G GP G G G GP G G GP G GP GP GP G G G GP G G G GP G G G G GP GP G WWP2 TARBP2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 NEFM 25402006 pred G G GP G GP G G GP G G G G WWP2 CHIA 23023127 pred P P G G P G GP P P GP GP P G GP GP G G P P P G P GP P G WWP2 IFNB1 23023127 pred P P P P P P P P P P P P P P P P P P P WWP2 RNF31 23023127 pred P P G G G GP P P G GP GP GP P GP GP GP G GP P P GP GP G P GP WWP2 TGFB1 23023127 pred G G G G G G G G G G G G G G G GP G G G G GP G G GP G GP G G WWP2 UBE2Z 16082366 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CD2AP 23023127 pred GP GP G G P G G GP GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP WWP2 UBE2N 23023127, 16082366 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 LATS1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 MBD2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 HAVCR1 23023127 pred G G G WWP2 JAG2 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 EFNB3 23023127 pred G G G G GP P P G P P G GP G G G P G WWP2 SLC9A3R1 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 PACSIN1 23023127 pred G GP G G P G P GP G WWP2 GSK3A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PRTN3 25402006 pred P G G P G P P P P P P GP P P G P P G WWP2 GFI1 23023127 pred P P G G P P P P P P P GP P P P P P P P G P P WWP2 USP9X 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CCL13 23023127 pred G G G G G G G G G G G WWP2 UBE2D1 23023127, 16082366 pred GP G G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP G GP G G GP GP G WWP2 SKI 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CHGB 25402006 pred GP G G G GP G G GP G G G G GP GP G GP G GP G G GP GP G G WWP2 CPA2 23023127 pred G G G G G G G G G G G G G G G G G G GP G G G G G G G G G G WWP2 MAD2L1 23023127 pred P G G P P GP P P P GP G GP P G P P GP P GP G GP GP WWP2 HPX 23023127 pred G GP G G G GP G G GP GP GP G G G G G G G G G G GP GP G WWP2 VIM 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G G GP G GP G G G G G G G G GP G WWP2 ITCH 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CD28 23023127 pred G G G G G WWP2 RNF4 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP G G G GP GP GP GP G G GP GP G WWP2 PVR 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G WWP2 UBR2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PIK3R1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2T 23023127, 16082366 pred G G G GP G GP P P P GP GP P GP P G GP P GP G WWP2 FBXL5 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 PON1 23023127 pred P GP G G GP P P P GP P GP GP GP GP G P GP P GP GP P GP G WWP2 NCS1 23023127 pred G G GP G GP G G G G GP G G G G G G G G WWP2 ZFYVE9 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G GP G GP GP G G GP G GP GP G WWP2 JPH2 23023127 pred P G P GP GP P P G GP P P P GP GP GP GP G GP P G WWP2 SYVN1 23023127 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 EP300 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 JUNB 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CCL1 23023127 pred P P P P P P P P P P P WWP2 ADAD1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CIDEA 23023127 pred G G G G G G G G WWP2 SERGEF 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP GP G WWP2 ALYREF 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 TNFRSF4 23023127 pred P GP G G WWP2 CYLD 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP G GP GP WWP2 HLA-A 23023127 pred WWP2 HECW2 23023127 pred GP GP G G G GP G GP GP G GP G GP G G P GP GP G GP GP GP 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GP G GP GP G WWP2 LATS2 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 KLK13 23023127 pred G G G G G GP G G GP G GP G G GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 DYNLT1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 CDK1 23023127 pred GP G G G GP P P P GP G GP G GP P GP G GP GP WWP2 SP1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 FKBP1A 23023127 pred G GP G G G GP G G GP G GP GP G G G GP GP G GP G GP GP GP G GP G GP GP G WWP2 IL1RAPL1 23023127 pred P P G G G GP G GP GP G P GP P P P GP G GP G P P P GP P P P G WWP2 MED15 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CBLB 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G WWP2 HIPK3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 AGAP4 23023127 pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G G G GP GP G GP GP G NCF1B WWP2 23023127 pred WWP2 CD300LG 23023127 pred GP GP G G P G GP GP GP GP GP GP G GP P G GP G GP P GP GP GP G P GP G WWP2 SHH 23023127 pred GP GP G G G GP G P GP G GP G GP GP GP GP P G P GP P GP GP GP GP WWP2 CCL5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 APOBEC3F 23023127 pred G G G G G G G G G G G G G G G G G G G G G WWP2 ARIH2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 UBA2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G WWP2 WWP1 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CUL3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CAND1 21836163 pred G GP G G G G G G GP G GP GP G G G GP G G G G G G GP GP GP G G GP G WWP2 UFC1 16082366 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2H 23023127, 16082366 pred GP GP G G G GP G GP G G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PARD6A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP GP G WWP2 CSNK1G2 25402006 pred G G G G G G G G GP G G G G G G GP G G GP G G G G G GP G GP G G WWP2 USP33 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CACNB4 WWP2 23023127 pred P P G GP G P P G P P P P P GP P P GP GP P P P P WWP2 MEGF8 25402006 pred G GP G G G GP G GP GP G GP GP G G G GP GP G P G GP G G GP G GP G G WWP2 PPBP 23023127 pred G G P G P GP G WWP2 CHFR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 ACTB 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UHMK1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 PACSIN3 23023127 pred GP GP GP G GP P P GP P G G GP GP G GP GP GP GP GP GP GP P G WWP2 RIPK1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 TRIM33 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 PSMB3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 UBE2A 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 UBE2E2 23023127, 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 BARD1 23023127 pred P G G P P GP P P P GP G GP P G P P GP P GP P G GP GP G WWP2 GRB2 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 FBXO8 21836163 pred GP G G G G GP G G GP G G GP G G G GP GP G GP G GP GP GP G GP G GP GP G WWP2 RAD23B 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 RUNX2 25402006 pred GP G G G G G G G G G GP G G G G G G G GP G G G G WWP2 GTF2A2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 TMPRSS2 23023127 pred P G GP G GP G GP GP GP GP GP G GP WWP2 CACNB1 25402006 pred P G G G G GP G G P G GP G G GP GP GP G GP G GP GP G GP GP P GP G WWP2 JPH1 23023127 pred G G G G GP G G G G G G G G G G GP G G G G WWP2 STRAP 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 HS3ST5 23023127 pred G G G GP G GP G P P P GP G G G GP GP P G WWP2 TNFSF4 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP P GP G P G P GP GP GP GP G GP GP G WWP2 PLCG2 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP G GP GP G WWP2 BAIAP2 25402006 pred P P G G G GP G GP P G GP GP GP GP P GP G GP G GP GP P P P GP GP G WWP2 PDPK1 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 CHRD 25402006 pred GP GP G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP P G WWP2 UBE2V2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 JPH3 23023127 pred P P G GP G P G P P P P P GP P G P P P P P P WWP2 GOPC 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 CDC20 23023127 pred P G G G GP P P GP G G P GP GP GP WWP2 CDK5 23023127 pred P GP G GP G P P G GP GP P GP GP GP P G P G P P P P P WWP2 NELL1 25402006 pred P G GP P P G GP P P P P GP P G P P P P P P P WWP2 CBL 25402006 pred G GP G G G GP G G GP G GP G GP GP G G GP G G G G G G G G G G GP G WWP2 WWC1 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 HUWE1 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 GNAI2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 FAF1 23023127 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 DGCR8 23023127 pred P P P P P P P P P P P P P P P P P P P WWP2 SNX12 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G WWP2 TP63 25402006 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G WWP2 EFEMP1 25402006 pred GP G G G G GP G G G G G GP GP G G G GP G G G G GP G G G G GP G G WWP2 GRN 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 RAD23A 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 PSMD3 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 SMARCA2 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 YY1 25402006 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 RIMBP2 23023127 pred P P G GP G P P G GP P P G GP GP GP G P P P GP P GP P G WWP2 UBE2F 16082366 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 NFKBIA 23023127 pred G GP G G G GP G GP GP G G G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 NEDD4L 25402006, 23023127, 21836163 pred GP GP G GP G GP GP G GP G GP P G GP GP G GP G GP GP G G GP G GP G WWP2 PSMA3 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G WWP2 CCL3 23023127 pred WWP2 FBXL3 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WWP2 UBE2D4 23023127, 16082366 pred GP G G G G GP G G GP G GP GP GP GP G G GP G GP G GP GP G GP G G GP GP G MEGF11 WWP2 25402006 pred P G GP P P G P P P P P GP P P P P P P P WWP2 MAGI1 25402006 pred G G G G G G G G GP G GP GP GP G G GP G G GP G G G GP G GP G GP G G WWP2 C9 23023127 pred P P P GP P P P WWP2 CLEC4M 23023127 pred G G G G G G G G G G G G GP G G G G G G G G G G G G G WWP2 SMAD4 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G WWP2 TRAF2 23023127 pred P P P P P P P P P P P P P P P P P G GP P WWP2 CNOT4 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G WWP2 UBE2G2 23023127 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP G G GP G GP GP G WWP2 LEMD3 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 IL10 23023127 pred P P P P P P P P GP P P P P WWP2 HCFC1 23023127 pred GP GP G G G GP G GP G G GP GP GP G G G GP G G G G GP GP GP G G GP GP G WWP2 PPIA 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G WWP2 INS 23023127 pred G GP G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B WWP2 NDFIP2 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 15252135,20522958 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_148122|HPRD_10626 prey|- bait|- WWP2 UBP1 MI:0004(affinity chromatography technology) 21956701 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_160938 bait prey WWP2 WIPF1 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114883 prey bait WWP2 CDC34 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226065 bait prey WWP2 PDLIM7 MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0468(hprd)|MI:0471(mint) UniProt_153065|MINT_67950|BIOGRID_80225|HPRD_21962|MINT_38721 unspecified role|prey|prey|-|prey unspecified role|bait|bait|-|bait WWP2 IL6R MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_36735 - - WWP2 UBE2D2 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226062 bait prey WWP2 SCNN1A MI:0096(pull down)|MI:0493(in vivo) 12167593 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_101714|HPRD_6589 bait|- prey|- WWP2 ADARB1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21847096 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(intact)|(intact)|(intact) UniProt_116577|BIOGRID_141610|UniProt_116580|UniProt_116581|UniProt_116579|UniProt_116578 prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait WWP2 ATN1 MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16713569,9647693 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(biogrid)|(intact)|(biogrid)|MI:0468(hprd)|MI:0471(mint)|(biogrid) MINT_50556|BIOGRID_114708|UniProt_85735|BIOGRID_215265|HPRD_10623|MINT_82844|BIOGRID_114712 prey|prey|bait|prey|-|prey|bait bait|bait|prey|bait|-|bait|prey WWP2 EWSR1 MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_20507 - - WWP2 POU5F1 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 19274063,22387393 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0220(ubiquitination reaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(intact) UniProt_98528|BIOGRID_149794|UniProt_98527|UniProt_98529|BIOGRID_185340|BIOGRID_149793|BIOGRID_149796|UniProt_98530 neutral component|bait|bait|prey|prey|prey|bait|bait neutral component|prey|prey|bait|bait|bait|prey|prey WWP2 EWSR1 MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_78996|UniProt_151849 prey|unspecified role bait|unspecified role WWP2 AZI1 MI:0004(affinity chromatography technology) 21956701 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_160937 bait prey WWP2 SFTPC MI:0096(pull down) 19366705 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_148323 bait prey WWP2 PTEN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 15717329,22427670,24063548 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_289353|BIOGRID_152945|BIOGRID_185173 prey|prey|prey bait|bait|bait WWP2 SMAD3 MI:0676(tandem affinity purification)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 18729074,21258410,23938591 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(biogrid)|(biogrid)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid) UniProt_97032|UniProt_112688|BIOGRID_153695|BIOGRID_153698|UniProt_112679|UniProt_112681|BIOGRID_218589|BIOGRID_310062|BIOGRID_153704 prey|bait|bait|prey|bait|prey|prey|bait|bait prey|prey|prey|bait|prey|bait|bait|prey|prey WWP2 EGR2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19651900 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_146980|BIOGRID_146978|BIOGRID_146981 bait|bait|bait prey|prey|prey WWP2 SMARCC1 MI:0096(pull down) 17526739 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_141907 bait prey WWP2 EWSR1 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_66404|MINT_37223 prey|prey bait|bait WWP2 PSMD10 MI:0004(affinity chromatography technology) 22387393 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_185339 prey bait WWP2 DIDO1 MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_152642|BIOGRID_81431 unspecified role|bait unspecified role|prey WWP2 HNRNPUL1 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114885 prey bait WWP2 TRAF4 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114771 prey bait WWP2 USP7 MI:0096(pull down)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0096(pull down)|MI:0018(two hybrid) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|(intact)|MI:0471(mint)|(biogrid) MINT_50557|HPRD_27107|UniProt_85913|MINT_82845|BIOGRID_215420 prey|-|prey|prey|prey bait|-|bait|bait|bait WWP2 UBE2D3 MI:0114(x-ray crystallography) 23644597 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_281011 prey bait WWP2 UBE2K MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226066 bait prey WWP2 TFAP2A MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_1064 - - WWP2 RASA1 MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_34971 - - WWP2 ARRDC4 MI:0428(imaging technique) 23236378 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248912 prey bait WWP2 SF1 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_66841|MINT_37659 prey|prey bait|bait WWP2 S1PR1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21555855 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_161545|BIOGRID_161547|BIOGRID_161546 prey|prey|bait bait|bait|prey WWP2 VASP MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid) HPRD_21758|UniProt_153054|MINT_38710|MINT_67939|BIOGRID_80213 -|unspecified role|prey|prey|prey -|unspecified role|bait|bait|bait WWP2 ARRDC1 MI:0428(imaging technique)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 21191027,22315426,23236378 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_248899|BIOGRID_160735|BIOGRID_207028 prey|prey|bait bait|bait|prey WWP2 SEC24D MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114778 prey bait WWP2 DAG1 MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_31370 - - WWP2 UBE2J2 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226064 bait prey WWP2 SPG20 MI:0018(two hybrid) 19307600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_197096 prey bait WWP2 SCN5A MI:0096(pull down) 15548568 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_182620 prey bait WWP2 SCNN1B MI:0047(far western blotting)|MI:0493(in vivo)|MI:0096(pull down) 11244092,12167593 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_109066|HPRD_7694|BIOGRID_101715 prey|-|bait bait|-|prey WWP2 SCNN1G MI:0096(pull down)|MI:0493(in vivo) 12167593 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_101716|HPRD_7699 bait|- prey|- WWP2 SMAD7 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21258410,22773947 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) BIOGRID_153696|UniProt_112689|BIOGRID_197930|UniProt_112685|UniProt_112686|UniProt_112680|UniProt_112683|BIOGRID_153699|BIOGRID_153703 bait|bait|prey|bait|prey|bait|prey|prey|bait prey|prey|bait|prey|bait|prey|bait|bait|prey WWP2 TP53BP2 MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_10625 - - WWP2 CUL1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_204612 prey bait WWP2 UBE2L3 MI:0096(pull down)|MI:0004(affinity chromatography technology) 17719543,19274063 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_118763|BIOGRID_226105 bait|bait prey|prey WWP2 CLCN5 MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_5091 - - WWP2 UBE2E1 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 17526739,19274063 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0220(ubiquitination reaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid) UniProt_98528|BIOGRID_226106|BIOGRID_225967 neutral component|bait|bait neutral component|prey|prey WWP2 SCAMP3 MI:0493(in vivo)|MI:0018(two hybrid) 19158374 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_33251|BIOGRID_116154 -|prey -|bait WWP2 ARRDC3 MI:0428(imaging technique)|MI:0428(imaging technique) 23236378 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_248909|BIOGRID_248901 prey|prey bait|bait WWP2 DIDO1 MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_21963 - - WWP2 CPSF6 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|(intact)|MI:0468(hprd)|(biogrid) MINT_39628|MINT_68901|UniProt_153578|HPRD_21961|BIOGRID_80750 prey|prey|unspecified role|-|prey bait|bait|unspecified role|-|bait WWP2 WBP2 MI:0686(unspecified method) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_99486 prey bait WWP2 UBE2E3 MI:0415(enzymatic study) 22496338 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_226063 bait prey WWP2 WBP1 MI:0492(in vitro)|MI:0686(unspecified method) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_10624|BIOGRID_99483 -|prey -|bait WWP2 IL2RG MI:0492(in vitro) 9169421 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_5799 - - WWP2 FBXL15 MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 21572392 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_115330|BIOGRID_258628 bait|bait prey|prey WWP2 TNK2 MI:0096(pull down) 19144635 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_145410 bait prey WWP2 VPS11 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_242493 prey bait WWP2 POLR2A MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 17526739 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_141903|BIOGRID_141904|BIOGRID_143356|BIOGRID_141905 prey|bait|bait|prey bait|prey|prey|bait WWP2 EZH2 MI:0004(affinity chromatography technology) 24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_305677 prey bait WWP2 SMAD2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 18729074,21258410 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(biogrid)|(intact)|(biogrid)|(intact) BIOGRID_153697|UniProt_112687|UniProt_112678|BIOGRID_153694|UniProt_112682|BIOGRID_218575|UniProt_97031 prey|bait|bait|bait|prey|prey|prey bait|prey|prey|prey|bait|bait|bait WWP2 SF1 MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|- (biogrid)|(intact)|MI:0468(hprd) BIOGRID_79406|UniProt_152248|HPRD_21727 prey|unspecified role|- bait|unspecified role|- WWP2 PTPN14 MI:0004(affinity chromatography technology) 22948661 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_208820 prey bait WWP2 RNF11 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid) UniProt_78526|MINT_60202|HPRD_37629|MINT_31437|BIOGRID_259407 prey|prey|-|prey|prey bait|bait|-|bait|bait WWP2 UBC MI:0114(x-ray crystallography)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10,17719543,19343052,21139048,21572392,21890473,22496338,23644597,23938591 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(biogrid)|MI:0471(mint)|(biogrid)|(intact)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_281006|UniProt_99930|BIOGRID_211526|MINT_71094|BIOGRID_310063|UniProt_183940|BIOGRID_258634|MINT_41484|BIOGRID_153306|BIOGRID_118768|BIOGRID_169041|BIOGRID_172971 bait|prey|bait|prey|prey|prey|bait|prey|prey|bait|prey|prey prey|bait|prey|bait|bait|bait|prey|bait|bait|prey|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality WWP2 WWP2 21258410,19997087,23938591,19997087,19997087 0007,0004,0004,0415,0096 LC WWP2 SMAD7 21258410,21258410,21258410,21258410,21258410,22773947 0004,0415,0096,0006,0007,0004 LC WWP2 LDLRAD4 26186194 0004 HT WWP2 UBC 19343052,17719543,19343052,23938591 0096,0096,0004,0004 LC WWP2 PTEN 21532586,24063548,15717329,21532586,22427670 0096,0004,0004,0004,0004 LC WWP2 UBE2D3 25266661,23644597,25723849 0096,0096,0096 LC WWP2 UBE2G1 22939629 0401 HT WWP2 UBE2D2 22496338,25723849 0096,0096 LC WWP2 UBE2L3 19274063,17719543,26949039,17996703,25723849 0096,0096,0096,0096,0096 LC WWP2 SMAD3 21258410,21258410,18729074,21258410,21258410 0004,0415,0676,0006,0007 LC WWP2 DGCR2 26186194 0004 HT WWP2 POU5F1 19274063,19274063,19274063,19274063,19274063,22387393,19274063 0007,0006,0415,0096,0997,0004,0004 LC WWP2 CUL1 21145461 0004 HT WWP2 SMAD2 21258410,18729074,18729074,21258410,21258410 0004,0004,0676,0006,0007 LC WWP2 TMEM132A 26496610,26496610 0007,0004 HT WWP2 AMOT 26186194 0004 HT WWP2 FIP1L1 26496610,26496610 0007,0004 HT WWP2 Q7Z4S8 26186194 0004 HT WWP2 FBXO11 26186194 0004 HT WWP2 AMOTL1 26186194 0004 HT WWP2 ARRDC1 22315426,26186194 0004,0004 LC,HT WWP2 CPSF7 26496610,26496610 0007,0004 HT WWP2 SIDT2 26496610,26496610 0007,0004 HT WWP2 FAM168A 26186194 0004 HT WWP2 ARRDC3 26490116,23236378,23236378,23236378 0004,0018,0007,0004 LC WWP2 SORT1 26496610,26496610 0007,0004 HT WWP2 TUBGCP2 26496610,26496610 0007,0004 HT WWP2 NDFIP1 26186194 0004 HT WWP2 VPS11 22939629 0401 HT WWP2 MKNK2 26496610,26496610 0007,0004 HT WWP2 Q9P0T0 21258410,18729074,21258410 0004,0004,0415 LC WWP2 LDLRAD4 26186194 0004 HT WWP2 UBE2G1 22939629 0401 HT WWP2 DGCR2 26186194 0004 HT WWP2 CUL1 21145461 0004 HT WWP2 TMEM132A 26496610,26496610 0007,0004 HT WWP2 AMOT 26186194 0004 HT WWP2 FIP1L1 26496610,26496610 0007,0004 HT WWP2 Q7Z4S8 26186194 0004 HT WWP2 FBXO11 26186194 0004 HT WWP2 AMOTL1 26186194 0004 HT WWP2 ARRDC1 26186194 0004 HT WWP2 CPSF7 26496610,26496610 0007,0004 HT WWP2 SIDT2 26496610,26496610 0007,0004 HT WWP2 FAM168A 26186194 0004 HT WWP2 SORT1 26496610,26496610 0007,0004 HT WWP2 TUBGCP2 26496610,26496610 0007,0004 HT WWP2 NDFIP1 26186194 0004 HT WWP2 VPS11 22939629 0401 HT WWP2 MKNK2 26496610,26496610 0007,0004 HT WWP2 WWP2 21258410,19997087,23938591,19997087,19997087 0007,0004,0004,0415,0096 LC WWP2 SMAD7 21258410,21258410,21258410,21258410,21258410,22773947 0004,0415,0096,0006,0007,0004 LC WWP2 UBC 19343052,17719543,19343052,23938591 0096,0096,0004,0004 LC WWP2 PTEN 21532586,24063548,15717329,21532586,22427670 0096,0004,0004,0004,0004 LC WWP2 UBE2D3 25266661,23644597,25723849 0096,0096,0096 LC WWP2 UBE2D2 22496338,25723849 0096,0096 LC WWP2 UBE2L3 19274063,17719543,26949039,17996703,25723849 0096,0096,0096,0096,0096 LC WWP2 SMAD3 21258410,21258410,18729074,21258410,21258410 0004,0415,0676,0006,0007 LC WWP2 POU5F1 19274063,19274063,19274063,19274063,19274063,22387393,19274063 0007,0006,0415,0096,0997,0004,0004 LC WWP2 SMAD2 21258410,18729074,18729074,21258410,21258410 0004,0004,0676,0006,0007 LC WWP2 ARRDC1 22315426 0004 LC WWP2 ARRDC3 26490116,23236378,23236378,23236378 0004,0018,0007,0004 LC WWP2 Q9P0T0 21258410,18729074,21258410 0004,0004,0415 LC VPS37C WWP2 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT A8K6V0 WWP2 21516116 0018 HT WWP2 WWP2 22496338,19997087,17719543,26949039,19997087,19997087,17996703 0415,0004,0415,0415,0415,0096,0415 LC WWP2 SCAMP3 19158374 0018 LC WWP2 SMAD7 21258410,21258410,21258410,15761153,21258410,21258410 0004,0415,0096,0019,0006,0007 LC,HT WWP2 WIPF1 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT WWP2 GRAP2 27107012,27107012 1356,2215 HT WWP2 SEC24D 21516116 0018 HT WWP2 SNRPC 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 UBB 17719543 0415 LC WWP2 UBC 22496338,23644597,25723849 0415,0415,0415 LC WWP2 EGR2 19651900,19651900,19651900 0096,0018,0004 LC WWP2 TGFBR1 15761153 0019 HT WWP2 VASP 16189514,16189514 0398,0018 HT WWP2 SCNN1B 11244092 0047 LC WWP2 ATN1 16713569,9647693,9647693,16713569 0397,0096,0018,0018 HT,LC WWP2 UBE2G1 22939629 0401 LC WWP2 SMAD3 21258410,21258410,15761153,21258410,21258410 0004,0415,0019,0006,0007 LC,HT WWP2 EWSR1 16189514,16189514 0398,0018 HT WWP2 POU5F1 19274063,19274063,19274063,19997087,19274063,19274063,19274063 0007,0006,0415,0415,0096,0997,0004 LC WWP2 SF1 16189514,16189514 0398,0018 HT WWP2 SMAD2 15761153 0019 HT WWP2 SMAD1 15761153 0019 HT WWP2 CPSF6 16189514,16189514 0398,0018 HT WWP2 LGALS9B 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 SPG20 19307600 0018 LC WWP2 ARRDC1 21191027,23236378,21516116 0018,0018,0018 LC,HT WWP2 ANKRD44 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 Q8WU02 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 PSMF1 27107012,27107012 1356,2215 HT WWP2 USP7 16713569,16713569 0397,0018 HT WWP2 ARRDC3 23236378,23236378,23236378 0018,0007,0004 LC WWP2 FBXL18 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 DIDO1 16189514,16189514 0398,0018 HT WWP2 HNRNPUL1 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT WWP2 TRAF4 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT WWP2 RUSC1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT WWP2 PAIP1 25266661,25266661,25266661 0096,0415,0004 LC WWP2 VPS11 22939629 0401 LC WWP2 PDLIM7 16189514,21516116,25416956,25416956,25416956,16189514,25416956 0398,0018,1112,0397,0018,0018,1356 HT WWP2 Q9P0T0 21258410,23938591,21258410,21516116 0004,0415,0415,0018 LC,HT WWP2 NOTCH3 25356737,25356737,25356737 0096,0415,0004 LC WWP2 RNF11 15231748 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O14828 O00308 SCAMP3 WWP2 0.309 19158374 Q5JRV8 O00308 TMEM255A WWP2 0.126 26186194 P61077 O00308 UBE2D3 WWP2 0.671 23644597,25723849,25266661 Q5TAL4 O00308 Q5TAL4 WWP2 0.332 25416956 O43541 O00308 SMAD6 WWP2 0.21 24850914 O15165 O00308 LDLRAD4 WWP2 0.126 26186194 P62253 O00308 UBE2G1 WWP2 0.081 22939629 Q8N0X7 O00308 SPG20 WWP2 0.309 19307600 Q8N8A2 O00308 ANKRD44 WWP2 0.454 25416956 Q9HCE1 O00308 MOV10 WWP2 0.126 22658674 Q8R0W6 O00308 NDFIP1 WWP2 0.21 11748237 Q9H074 O00308 PAIP1 WWP2 0.74 25266661 Q9NV92 O00308 NDFIP2 WWP2 0.21 20522958 Q9H270 O00308 VPS11 WWP2 0.081 O75832 O00308 PSMD10 WWP2 0.21 22387393 P0CG48 O00308 UBC WWP2 0.794 23644597,19343052,23938591,25723849,22496338 P0CK58 O00308 P0CK58 WWP2 0.126 22810586 P03207 O00308 P03207 WWP2 0.126 22810586 P13285 O00308 LMP2 WWP2 0.126 22810586 P04629 O00308 NTRK1 WWP2 0.126 25921289 Q9HAC8 O00308 UBTD1 WWP2 0.236 unassigned1304 Q9HBH9 O00308 MKNK2 WWP2 0.236 26496610 P08228 O00308 SOD1 WWP2 0.236 26496610 Q8N684 O00308 CPSF7 WWP2 0.236 26496610 Q8N7B9 O00308 EFCAB3 WWP2 0.236 unassigned1304 Q8NCT1 O00308 ARRDC4 WWP2 0.376 23236378 Q8NHY3 O00308 GAS2L2 WWP2 0.236 unassigned1304 Q9Y3C5 O00308 RNF11 WWP2 0.332 15231748 Q96GM5 O00308 SMARCD1 WWP2 0.236 unassigned1304 Q99523 O00308 SORT1 WWP2 0.236 26496610 Q9BSJ2 O00308 TUBGCP2 WWP2 0.236 26496610 O15105 O00308 SMAD7 WWP2 0.659 22773947,21258410 Q15599 O00308 SLC9A3R2 WWP2 0.236 unassigned1304 Q9DC28 O00308 CSNK1D WWP2 0.236 26496610 Q99954 O00308 SMR3A WWP2 0.236 unassigned1304 Q24JP5 O00308 TMEM132A WWP2 0.236 26496610 Q3B8N2 O00308 LGALS9B WWP2 0.454 25416956 O00308 A5D8V6 WWP2 VPS37C 0.583 25416956,unassigned1304 Q01860 O00308 POU5F1 WWP2 0.794 19274063,19997087,22387393 P14678 O00308 SNRPB WWP2 0.236 unassigned1304 O00308 A0A087WWA7 WWP2 DVL1 {ECO:0000313|ENSEMBL:ENSP00000480077} 0.236 unassigned1304 O14641 O00308 DVL2 WWP2 0.623 26701932 O00308 A8MYP8 WWP2 ODF3B 0.236 unassigned1304 O43516 O00308 WIPF1 WWP2 0.636 21516116,25416956 Q8IZ03 O00308 IFIT2 WWP2 0.236 unassigned1304 P54646 O00308 PRKAA2 WWP2 0.236 unassigned1304 P62837 O00308 UBE2D2 WWP2 0.523 25723849,22496338 Q86UU5 O00308 GGN WWP2 0.236 unassigned1304 Q71SY5 O00308 MED25 WWP2 0.236 unassigned1304 Q96LR5 O00308 UBE2E2 WWP2 0.236 unassigned1304 Q8TAE8 O00308 GADD45GIP1 WWP2 0.236 unassigned1304 Q96B67 O00308 ARRDC3 WWP2 0.82 23236378,26490116,unassigned1304 Q9Y272 O00308 RASD1 WWP2 0.236 unassigned1304 Q9HBE1 O00308 PATZ1 WWP2 0.236 unassigned1304 Q6UN15 O00308 FIP1L1 WWP2 0.236 26496610 Q7L5A3 O00308 FAM214B WWP2 0.236 unassigned1304 P36895 O00308 BMPR1A WWP2 0.236 26496610 Q8BL66 O00308 EEA1 WWP2 0.236 26496610 O75787 O00308 ATP6AP2 WWP2 0.236 26496610 P61964 O00308 WDR5 WWP2 0.236 unassigned1304 P40325 O00308 HUA1 WWP2 0.332 27107014 P11161 O00308 EGR2 WWP2 0.623 19651900 Q8N5I2 O00308 ARRDC1 WWP2 0.858 22315426,unassigned1304,23236378,21191027,21516116,26186194 Q9NR12 O00308 PDLIM7 WWP2 0.681 25416956,21516116,16189514 P84022 O00308 SMAD3 WWP2 0.876 18729074,25910212,21258410,23938591,21516116 P09234 O00308 SNRPC WWP2 0.376 unassigned1304,25416956 Q9BUJ2 O00308 HNRNPUL1 WWP2 0.722 21516116,25416956,unassigned1304 P60484 O00308 PTEN WWP2 0.731 15717329,21532586,24063548,22427670 P68036 O00308 UBE2L3 WWP2 0.843 26949039,17719543,17996703,25723849,19274063 O00308 O00308 WWP2 WWP2 0.948 17719543,17996703,22496338,23938591,19997087,26949039 Q93009 O00308 USP7 WWP2 0.286 16713569 Q8WU02 O00308 Q8WU02 WWP2 0.332 25416956 Q969T9 O00308 WBP2 WWP2 0.309 9169421 Q96D16 O00308 FBXL18 WWP2 0.332 25416956 Q96G27 O00308 WBP1 WWP2 0.309 9169421 Q92530 O00308 PSMF1 WWP2 0.236 27107012 Q9BTC0 O00308 DIDO1 WWP2 0.286 16189514 Q99732 O00308 LITAF WWP2 0.21 25963657 Q9UBU9 O00308 NXF1 WWP2 0.126 22658674 Q9UM47 O00308 NOTCH3 WWP2 0.74 25356737 P46379 O00308 BAG6 WWP2 0.21 24981174 Q13616 O00308 CUL1 WWP2 0.126 21145461 Q13635 O00308 PTCH1 WWP2 0.376 25092867 Q14524 O00308 SCN5A WWP2 0.309 15548568 P50552 O00308 VASP WWP2 0.286 16189514 P51168 O00308 SCNN1B WWP2 0.523 12167593,11244092 Q01844 O00308 EWSR1 WWP2 0.286 16189514 Q15637 O00308 SF1 WWP2 0.286 16189514 Q15884 O00308 FAM189A2 WWP2 0.183 25416956 Q15910 O00308 EZH2 WWP2 0.126 24457600 O75791 O00308 GRAP2 WWP2 0.236 27107012 O94855 O00308 SEC24D WWP2 0.332 21516116 P01106 O00308 MYC WWP2 0.376 26894970 P0CG47 O00308 UBB WWP2 0.033 17719543 P11686 O00308 SFTPC WWP2 0.309 19366705 P11940 O00308 PABPC1 WWP2 0.21 25266661 P21453 O00308 S1PR1 WWP2 0.376 21555855 P37088 O00308 SCNN1A WWP2 0.309 12167593 P49427 O00308 CDC34 WWP2 0.309 22496338 P51170 O00308 SCNN1G WWP2 0.309 12167593 P51668 O00308 UBE2D1 WWP2 0.309 25723849 P51965 O00308 UBE2E1 WWP2 0.309 19274063 P54259 O00308 ATN1 WWP2 0.659 16713569,9647693 P61086 O00308 UBE2K WWP2 0.309 22496338 P78563 O00308 ADARB1 WWP2 0.507 21847096 P98153 O00308 DGCR2 WWP2 0.126 26186194 Q07912 O00308 TNK2 WWP2 0.309 19144635 Q14152 O00308 EIF3A WWP2 0.21 25266661 Q15796 O00308 SMAD2 WWP2 0.523 21258410,18729074 Q16630 O00308 CPSF6 WWP2 0.286 16189514 Q4VCS5 O00308 AMOT WWP2 0.126 26186194 Q86XK2 O00308 FBXO11 WWP2 0.126 26186194 Q8IY63 O00308 AMOTL1 WWP2 0.126 26186194 Q8N2K1 O00308 UBE2J2 WWP2 0.309 22496338 Q8WUM4 O00308 PDCD6IP WWP2 0.21 26490116 Q92567 O00308 FAM168A WWP2 0.126 26186194 Q969T4 O00308 UBE2E3 WWP2 0.472 unassigned1304,22496338 Q9BT67 O00308 NDFIP1 WWP2 0.126 26186194 Q9BUZ4 O00308 TRAF4 WWP2 0.722 21516116,25416956,unassigned1304 Q9BVN2 O00308 RUSC1 WWP2 0.454 25416956 Q9H469 O00308 FBXL15 WWP2 0.376 21572392 Q08909 O00308 Q08909 WWP2 0.332 27107014

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 VPS37C WWP2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DVL2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SCAMP3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMAD7 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 LDLRAD4 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 WIPF1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMAD6 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ATP6AP2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 GRAP2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PSMD10 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SEC24D MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SOD1 MI:0362 inference MI:0461 interaction database WWP2 MYC MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NTRK1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ADRB2 MI:0362 inference MI:0461 interaction database WWP2 SNRPC MI:0045 experimental interaction detection MI:0461 interaction database WWP2 RBP1 MI:0362 inference MI:0461 interaction database WWP2 UBB MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBC MI:0045 experimental interaction detection MI:0461 interaction database WWP2 EGR2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SFTPC MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PABPC1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 S1PR1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 POLR2A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 BMPR1A MI:0362 inference MI:0461 interaction database WWP2 TGFBR1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SCNN1A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NOTCH1 MI:0362 inference MI:0461 interaction database WWP2 NEDD4 MI:0362 inference MI:0461 interaction database WWP2 SOX2 MI:0362 inference MI:0461 interaction database WWP2 CSNK1D MI:0362 inference MI:0461 interaction database WWP2 CDC34 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 VASP MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SCNN1B MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SCNN1G MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2D1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2E1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NUDT6 MI:0362 inference MI:0461 interaction database WWP2 ATN1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 GSC MI:0362 inference MI:0461 interaction database WWP2 PTEN MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2D3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2K MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2D2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2L3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ADARB1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMAD3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DGCR2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 EWSR1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 POU5F1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NOTCH2 MI:0362 inference MI:0461 interaction database WWP2 POU5F1B MI:0362 inference MI:0461 interaction database WWP2 TNK2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 CUL1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PTCH1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 EIF3A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SCN5A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 LAPTM4A MI:0362 inference MI:0461 interaction database WWP2 EEA1 MI:0362 inference MI:0461 interaction database WWP2 SF1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PTPN14 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMAD2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMAD1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 FAM189A2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 EZH2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 CDC37 MI:0362 inference MI:0461 interaction database WWP2 CPSF6 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 TMEM132A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 LGALS9B MI:0045 experimental interaction detection MI:0461 interaction database WWP2 AMOT MI:0045 experimental interaction detection MI:0461 interaction database WWP2 TMEM255A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 FIP1L1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DTX2 MI:0362 inference MI:0461 interaction database WWP2 LAPTM4B MI:0362 inference MI:0461 interaction database WWP2 FBXO11 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DTX1 MI:0362 inference MI:0461 interaction database WWP2 AMOTL1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SPG20 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2J2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ARRDC1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 CPSF7 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ANKRD44 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 ARRDC4 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 GLIS3 MI:0362 inference MI:0461 interaction database WWP2 SMARCC2 MI:0362 inference MI:0461 interaction database WWP2 PDCD6IP MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PSMF1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 FAM168A MI:0045 experimental interaction detection MI:0461 interaction database WWP2 SMARCC1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 USP7 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 WBP2 MI:0362 inference MI:0461 interaction database WWP2 ARRDC3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 WBP1 MI:0362 inference MI:0461 interaction database WWP2 SUCLG2 MI:0362 inference MI:0461 interaction database WWP2 ITCH MI:0362 inference MI:0461 interaction database WWP2 FBXL18 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NEDD4L MI:0362 inference MI:0461 interaction database WWP2 SORT1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 LITAF MI:0045 experimental interaction detection MI:0461 interaction database WWP2 TUBGCP2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NDFIP1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DIDO1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 HNRNPUL1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 TRAF4 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 KATNB1 MI:0362 inference MI:0461 interaction database WWP2 RUSC1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PAIP1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PTPN23 MI:0362 inference MI:0461 interaction database WWP2 FBXL15 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 MKNK2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 PDLIM7 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NDFIP2 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 UBP1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 NOTCH3 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 CEP131 MI:0045 experimental interaction detection MI:0461 interaction database WWP2 DTX4 MI:0362 inference MI:0461 interaction database WWP2 RNF11 MI:0045 experimental interaction detection MI:0461 interaction database