PTM - CPLM Gene Name UniProt ID Type Position Code WWP2 O00308 Ubiquitination 632 K WWP2 O00308 Ubiquitination 17 K WWP2 O00308 Ubiquitination 825 K WWP2 O00308 Ubiquitination 820 K

PTM - dbPAF Gene Name UniProt ID Position Type Species WWP2 O00308 18 S Homo sapiens(Human) WWP2 O00308 193 T Homo sapiens(Human) WWP2 O00308 197 S Homo sapiens(Human) WWP2 O00308 207 T Homo sapiens(Human) WWP2 O00308 21 T Homo sapiens(Human) WWP2 O00308 211 S Homo sapiens(Human) WWP2 O00308 369 Y Homo sapiens(Human) WWP2 O00308 392 Y Homo sapiens(Human) WWP2 O00308 455 T Homo sapiens(Human) WWP2 O00308 467 T Homo sapiens(Human) WWP2 O00308 469 T Homo sapiens(Human) WWP2 O00308 491 Y Homo sapiens(Human) WWP2 O00308 528 S Homo sapiens(Human) WWP2 O00308 556 Y Homo sapiens(Human) WWP2 O00308 587 Y Homo sapiens(Human) WWP2 O00308 631 Y Homo sapiens(Human) WWP2 O00308 7 S Homo sapiens(Human) WWP2 O00308 87 S Homo sapiens(Human) WWP2 O00308 90 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O00308 S18-p Phosphorylation VALPFEksQLtLKVV O00308 T21-p Phosphorylation PFEksQLtLKVVSAK O00308 S87-p Phosphorylation HLDLKVWsCHtLRNE O00308 T90-p Phosphorylation LKVWsCHtLRNELLG O00308 T193-p Phosphorylation CFGGRSRtHRHsGAS O00308 S197-p Phosphorylation RSRtHRHsGASARTT O00308 T207-p Phosphorylation SARTTPAtGEQsPGA O00308 S211-p Phosphorylation TPAtGEQsPGARSRH O00308 Y369-p Phosphorylation TAEYVRNyEQWQSQR O00308 Y392-p Phosphorylation HFSQRFLyQSSSAST O00308 Y556-p Phosphorylation RGEEGLDyGGIAREW O00308 Y587-p Phosphorylation EYAGKNNyCLQINPA O00308 Y631-p Phosphorylation TGFTLPFykRMLNKR O00308 K473-sm Sumoylation NTRTTTFkDPRPGFE O00308 K17-ub Ubiquitination GVALPFEksQLtLKV O00308 K338-ub Ubiquitination PLPPGWEkRTDPRGR O00308 K413-ub Ubiquitination PLPPGWEkRQDNGRV O00308 K632-ub Ubiquitination GFTLPFykRMLNKRP

PTM - dbPTM UniProt ID Position Code Type Resources References O00308 211 S Phosphorylation Swiss-Prot 1010711 16964243;19007248;19413330 O00308 211 S Phosphorylation PhosphoELM.10011 16964243 O00308 632 K Ubiquitylation Phosphositeplus.1010730 21890473 O00308 211 S Phosphorylation Phosphositeplus.1010730 16964243;19664995;20363803;21406692;22115753 O00308 491 Y Phosphorylation Phosphositeplus.1010730 18083107 O00308 7 S Phosphorylation HPRD 9.0 20068231 O00308 211 S Phosphorylation HPRD 9.0 19007248,19664995,16964243 O00308 455 T Phosphorylation HPRD 9.0 20068231 O00308 467 T Phosphorylation HPRD 9.0 20068231 O00308 469 T Phosphorylation HPRD 9.0 18691976

PTM - HPRD Symbol Position Code Type References WWP2 16 T Phosphorylation 20068231 WWP2 211 S Phosphorylation 19007248,19664995,16964243 WWP2 28 T Phosphorylation 20068231 WWP2 30 T Phosphorylation 18691976 WWP2 455 T Phosphorylation 20068231 WWP2 467 T Phosphorylation 20068231 WWP2 469 T Phosphorylation 18691976 WWP2 7 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O00308 211 S 16964243 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O00308 211 Phosphoserine 16964243;21406692;23186163

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 11060 116244 - K Ubiquitination 19343052 11060 116244 - K Ubiquitination 21139048 11060 116244 - K Ubiquitination 21890473

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID WWP2 Homo sapiens (Human) 632 "632,FTLPFYKRMLNKR" 632:21890473 WWP2 Homo sapiens (Human) 250 "250,FTLPFYKRMLNKR" 250:21890473 WWP2 Homo sapiens (Human) 632 "632,FTLPFYKRMLNKR" 632:21890473 WWP2 Homo sapiens (Human) 632 "632,FTLPFYKRMLNKR" 632:21890473 WWP2 Homo sapiens (Human) 193 "193,FTLPFYKRMLNKR" 193:21890473