PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM44 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G TRIM10 TRIM35 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G P GP GP GP G ZBTB33 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G ZMYM2 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G UBE2D1 TRIM10 21143188 biogrid exp G G G G G G G G G G G G G G G G GP G G G G G GP G GP GP G PRKAB2 TRIM10 24722188 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G EMILIN3 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G TRIM10 ZNF148 25416956 biogrid,intact exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRIM10 UBE2D4 21143188 biogrid exp G G G G G G G G G G G G G G G G GP G G G G G GP G GP GP G TTC23 TRIM10 25416956 biogrid,intact exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRMT61B TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G LCK TRIM10 bci exp G G G G G G G G G G G G G G G ZNF324 TRIM10 26186194 biogrid exp G G G G G G G G P G G G G P P P GP G FAM193B TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G UBE2D2 TRIM10 21143188 biogrid exp G G G G G G G G G G G G G G G G GP G G G G G GP G GP GP G KLHL41 TRIM10 26186194 biogrid exp G G G G G G GP G G MTMR1 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G POLRMT TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G HSP90AA1 TRIM10 22939624 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G GP G WIZ TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRIM10 TBK1 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G HSP90AB1 TRIM10 22939624 intact exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G AMBRA1 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G G G G G G GP GP GP GP G ZNF624 TRIM10 26186194 biogrid exp P P P P P GP PSMA1 TRIM10 25416956 biogrid,intact exp G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRIM11 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G GP G G G G G P GP GP GP G UBE2D3 TRIM10 21143188 biogrid exp G G G G G G G G G G G G G G G G GP G G G G G GP G GP GP G RUNX1 TRIM10 bci exp P P P P P TRIM10 TRIM10 11331580 hprd,biogrid exp, ortho G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G DMC1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G GP G INPP5D TRIM10 23023127 pred G G G G G G G G G G G G G G G G GP G G G G G GP G G G G FASLG TRIM10 25402006 pred G G G G G G G G G G G G P G GP G G G G GP P P GP G MPP3 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G UBE2N TRIM10 23023127 pred G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G NPAP1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP G GP G CTAGE1 TRIM10 25402006 pred G G G G G G G G G G P G GP G G G G P P GP G BTNL3 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G C1QL1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM15 TRIM10 25402006 pred G G G G G G G GP G G G G G G GP GP GP P G TRIM15 TRIM10 25402006 pred G G G G G G G GP G G G G G G GP GP GP P G NCR2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G NTSR2 TRIM10 25402006 pred G G G G TRIM21 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G ITPK1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G TRIM10 TRAF6 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G TRIM48 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G GPR12 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G P G G G ANKRD54 TRIM10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G IFNA16 TRIM10 25402006 pred G G G G G G G P G G G G G P P P G ALPI TRIM10 25402006 pred GP GP TRIM10 ZNF835 25402006 pred G P P P P TRIM10 STUB1 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G IGHG3 TRIM10 23023127 pred UBE2B TRIM10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM63 TRIM10 23023127 pred G G G G PYHIN1 TRIM10 25402006 pred G G G G G G P G G G P P P P G GSTA1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G PRAMEF11 TRIM10 25402006 pred G G G G G G G G G G G G G G G G TRIM10 CCDC9 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G GLYAT TRIM10 25402006 pred G G IFNA17 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G INHBA TRIM10 23023127, 16082366 pred G G G G G P GP G G G P GP P P G GFRA4 TRIM10 25402006 pred TRIM74 TRIM10 23023127 pred EPB42 TRIM10 25402006 pred G G P P DAO TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CER1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM10 MYO16 25402006 pred G G P G P P P FGF5 TRIM10 25402006 pred G G G P G GP G P P P GP G CSH2 TRIM10 25402006 pred IL1RL1 TRIM10 25402006 pred G G G G P P G P P P P G DPF3 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G DNAJB5 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G ASH1L TRIM10 25402006 pred G G G G G G G G G G G G G G G G GP G G G G G G G G GP G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 TRIM10 25402006 pred P P P P P P SPI1 TRIM10 21836163 pred G G G G KRT2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G PSG6 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP GP G TCTN2 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G TRIM75P TRIM10 23023127 pred IGHG1 TRIM10 23023127 pred POU4F2 TRIM10 25402006 pred G G G G G G G G G G G G GYPB TRIM10 25402006 pred G G G G G G G G G G PSG9 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP GP G GABRR2 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G CPA2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G DLX4 TRIM10 25402006 pred G G G G G G G G G G G G G GP G G G G G G G GP GP GP G TREX2 TRIM10 25402006 pred P P P P COX6A2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G OR1F1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM10 TCF20 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G SEC14L5 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G TRIM50 TRIM10 23023127 pred G P P G P GP GP TAF4B TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G GP GP GP GP G TRPC7 TRIM10 25402006 pred P P NTRK3 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G SH2B2 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G PRY, PRY2, PRYP3, PRYP4 TRIM10 25402006 pred P P P P P P TRIM37 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G IGHG2 TRIM10 23023127 pred SLC30A3 TRIM10 25402006 pred G G P G P GP PGLYRP4 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G CYP2A6 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP G G PIWIL2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM10 CCRN4L 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G TRIM3 TRIM10 16082366 pred G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G IGHG4 TRIM10 23023127 pred ATP2B2 TRIM10 25402006 pred G G G G G G G G P G GP G G GP GP P P G OR2S2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G JAK2 TRIM10 23023127 pred G G G G G G G G G G G G G P G GP G G G GP GP GP HECW1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP P GP G ZNF507 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G NEUROD2 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G ITGA10 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM10 KLK13 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G HBQ1 TRIM10 25402006 pred G G NKX3-1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G DCLK2 TRIM10 25402006 pred G G G G G G G G GP G G G G P P P G HRH4 TRIM10 25402006 pred G G G G G P G P G G G GP GP P P G TRIM22 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G A1CF TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP G G RHAG TRIM10 25402006 pred G G P P P P CNR2 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G ACVR1B TRIM10 23023127 pred G G G G G G G G G G G G G G GP G G G G G G G G GP GP GP G CDKN2B TRIM10 23023127 pred G G G GP G GP G ACRV1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G GP G CLDN10 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP G G DRD5 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G GP GP G P2RY4 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G CRYBB3 TRIM10 25402006 pred P P P P TRIM28 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRIM54 TRIM10 23023127 pred G P G GP GP P P TRIM10 NTNG1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G KCNMB4 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CD80 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G CPN1 TRIM10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G GP GP GP GP G CDHR5 TRIM10 25402006 pred G G G GP GP BMP15 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM10 CDH10 25402006 pred G G G G G G G G G G G G G G GP G G G G G G G P GP GP G SPTA1 TRIM10 25402006 pred G G G G P G G GP P P GP G SMAP1 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G CLEC4M TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM65 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G G GP GP GP G OR2C1 TRIM10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TNFRSF13B TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G TRIM52 TRIM10 23023127 pred G G G G G G G G G G G G G G GP G GP G G G G G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q5W5X9 Q9UDY6 two hybrid 25416956 direct interaction X 2 Q9UQR1 Q9UDY6 two hybrid 25416956 direct interaction X 2 Q9UDY6 P62837 two hybrid 21143188 direct interaction X 2 Q9UDY6 P61077-3 two hybrid 21143188 direct interaction X 2 Q9UDY6 P62837 two hybrid 21143188 direct interaction X 2 Q9UDY6 P61077-3 two hybrid 21143188 direct interaction X 2 Q9UDY6 A0A024RA90 two hybrid 21143188 direct interaction X 2 Q9UDY6 P25786 two hybrid 25416956 direct interaction X 2 Q9UDY6 A0A087WW00 two hybrid 21143188 direct interaction X 2 Q9UDY6 A0A087WW00 two hybrid 21143188 direct interaction X 2 Q9UDY6 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q9UDY6 Q9UDY6 two hybrid 11331580 direct interaction X 2 O43741 Q9UDY6 two hybrid 24722188 direct interaction X 2 Q5W5X9 Q9UDY6 two hybrid prey pooling approach 25416956 physical association X 2 Q5W5X9 Q9UDY6 two hybrid array 25416956 physical association X 2 Q5W5X9 Q9UDY6 validated two hybrid 25416956 physical association X 2 Q9UQR1 Q9UDY6 two hybrid prey pooling approach 25416956 physical association X 2 Q9UQR1 Q9UDY6 two hybrid array 25416956 physical association X 2 Q9UQR1 Q9UDY6 validated two hybrid 25416956 physical association X 2 Q9UDY6 P25786 two hybrid prey pooling approach 25416956 physical association X 2 Q9UDY6 P25786 two hybrid array 25416956 physical association X 2 Q9UDY6 P25786 validated two hybrid 25416956 physical association X 2 Q9UDY6 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B HSP90AB1 TRIM10 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_125106 prey bait UBD TRIM10 MI:0004(affinity chromatography technology) 23862649 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284455 bait prey UBE2D3 TRIM10 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194209|BIOGRID_194212 bait|prey prey|bait UBE2D2 TRIM10 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194211|BIOGRID_194208 prey|bait bait|prey TRIM10 UBE2D4 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194279 bait prey HSP90AA1 TRIM10 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255433 bait prey UBE2D1 TRIM10 MI:0018(two hybrid)|MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194210|BIOGRID_194207 prey|bait bait|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UDY6 Q5W5X9 TRIM10 TTC23 0.454 25416956 Q9UDY6 O43741 TRIM10 PRKAB2 0.183 24722188 Q9UDY6 P25786 TRIM10 PSMA1 0.454 25416956 Q9UDY6 P07900 TRIM10 HSP90AA1 0.126 22939624 Q9UDY6 O14964 TRIM10 HGS 0.236 unassigned1304 Q9UDY6 P55040 TRIM10 GEM 0.236 unassigned1304 Q9UDY6 Q96IQ9 TRIM10 ZNF414 0.236 unassigned1304 Q9UDY6 Q9BWG6 TRIM10 SCNM1 0.236 unassigned1304 Q9UDY6 Q8TBB1 TRIM10 LNX1 0.236 unassigned1304 Q9UDY6 O00411 TRIM10 POLRMT 0.126 26186194 Q9UDY6 O60662 TRIM10 KLHL41 0.126 26186194 Q9UDY6 O75467 TRIM10 ZNF324 0.126 26186194 Q9UDY6 O95785 TRIM10 WIZ 0.126 26186194 Q9UDY6 P08238 TRIM10 HSP90AB1 0.126 22939624 Q9UDY6 P51668 TRIM10 UBE2D1 0.332 21143188 Q9UDY6 P61077 TRIM10 UBE2D3 0.332 21143188 Q9UDY6 P62837 TRIM10 UBE2D2 0.332 21143188 Q9UDY6 Q13613 TRIM10 MTMR1 0.126 26186194 Q9UDY6 Q86T24 TRIM10 ZBTB33 0.126 26186194 Q9UDY6 Q96DX7 TRIM10 TRIM44 0.332 unassigned1304,26186194 Q9UDY6 Q96F44 TRIM10 TRIM11 0.126 26186194 Q9UDY6 Q96PV7 TRIM10 FAM193B 0.126 26186194 Q9UDY6 Q9BVS5 TRIM10 TRMT61B 0.126 26186194 Q9UDY6 Q9C0C7 TRIM10 AMBRA1 0.126 26186194 Q9UDY6 Q9NT22 TRIM10 EMILIN3 0.126 26186194 Q9UDY6 Q9P2J8 TRIM10 ZNF624 0.126 26186194 Q9UDY6 Q9UBW7 TRIM10 ZMYM2 0.126 26186194 Q9UDY6 Q9UDY6 TRIM10 TRIM10 0.332 11331580 Q9UHD2 Q9UDY6 TBK1 TRIM10 0.126 26186194 Q9UPQ4 Q9UDY6 TRIM35 TRIM10 0.126 26186194 Q9Y2X8 Q9UDY6 UBE2D4 TRIM10 0.183 21143188 Q9UQR1 Q9UDY6 ZNF148 TRIM10 0.454 25416956