Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 12 117002658 rs2089222 G A rs2089222 8.00E-08 METHOTREXATE POLYGLUTAMIC ACID|ANTIMETABOLITES, ANTINEOPLASTIC|DOPA DECARBOXYLASE|MKL1 PROTEIN, HUMAN|IKAROS TRANSCRIPTION FACTOR|ARID5B PROTEIN, HUMAN|TRANSCRIPTION FACTORS|IKZF1 PROTEIN, HUMAN|ONCOGENE PROTEINS, FUSION|DNA-BINDING PROTEINS Acute lymphoblastic leukemia (childhood) HPOID:0006721 DOID:9952|DOID:12603 A intron GWASdb_drug 12 117002658 rs2089222 G A rs2089222 8.00E-08 Acute lymphoblastic leukemia (childhood) HPOID:0006721 DOID:9952|DOID:12603 A intron GWASdb_trait 12 117002658 rs2089222 G A rs2089222 8.00E-08 Nasopharyngeal carcinoma HPOID:0100630 DOID:9261 A intron GWASdb_trait 12 117013401 rs12227287 T C rs12227287 6.06E-04 Type 2 diabetes HPOID:0005978 DOID:9352 T intron GWASdb_trait