DNA & RNA Element - Circ2Traits | Common miRNA | Target mRNAs | Circular RNAs | Disease | hsa-miR-326 | ENSG00000089336.6, ENSG00000100181.15, ENSG00000117242.7, ENSG00000124835.2, ENSG00000126005.10, ENSG00000126005.10, ENSG00000131007.5, ENSG00000131009.4, ENSG00000132832.4, ENSG00000132832.4, ENSG00000141028.4, ENSG00000141028.4, ENSG00000145063.9, ENSG00000152931.6, ENSG00000159712.9, ENSG00000161103.6, ENSG00000164621.5, ENSG00000164621.5, ENSG00000167117.3, ENSG00000170846.11, ENSG00000170858.5, ENSG00000170983.3, ENSG00000173811.6, ENSG00000174365.14, ENSG00000174403.11, ENSG00000175061.9, | hsa_circ_000614 | acute myeloid leukemia (AML), up-regulated, microarray, 2008, Distinctive patterns of microRNA expression associated with karyotype in acute myeloid leukaemia. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | bladder cancer, down-regulated, northern blot, qRT-PCR etc, 2009, Identification of novel microRNA targets based on microRNA signatures in bladder cancer. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | cardiac hypertrophy, down-regulated, Northern blot, qRT-PCR etc, 2008, Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | cardiomyopathy, down-regulated, Northern blot, qRT-PCR etc, 2007, The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | colorectal cancer, down-regulated, microarray, 2009, Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer | hsa-miR-215 | ENSG00000100181.15, ENSG00000124915.6, ENSG00000162947.4, ENSG00000163364.4, ENSG00000167117.3, ENSG00000170846.11, ENSG00000175061.9, ENSG00000175699.8, ENSG00000175701.6, ENSG00000175772.10, ENSG00000176936.2, ENSG00000177640.11, ENSG00000179406.6, ENSG00000179676.6, ENSG00000179818.6, ENSG00000180139.7, ENSG00000180769.4, ENSG00000181171.5, ENSG00000181798.2, ENSG00000184441.4, ENSG00000186056.4, ENSG00000187979.3, ENSG00000188424.4, ENSG00000196096.3, ENSG00000196243.4, ENSG00000196273.3, EN | hsa_circ_000529, hsa_circ_000681 | colorectal cancer, down-regulated, Northern blot, qRT-PCR etc, 2009, p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | epithelial ovarian cancer (EOC), down-regulated, microarray, 2007, MicroRNA signatures in human ovarian cancer. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | glioblastoma multiforme (GBM), down-regulated, Northern blot, qRT-PCR etc, 2008, miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | head and neck squamous cell carcinoma (HNSCC), down-regulated, northern blot, qRT-PCR etc, 2009, Low-level expression of microRNAs let-7d and miR-205 are prognostic markers of head and neck squamous cell carcinoma. | hsa-miR-215 | ENSG00000100181.15, ENSG00000124915.6, ENSG00000162947.4, ENSG00000163364.4, ENSG00000167117.3, ENSG00000170846.11, ENSG00000175061.9, ENSG00000175699.8, ENSG00000175701.6, ENSG00000175772.10, ENSG00000176936.2, ENSG00000177640.11, ENSG00000179406.6, ENSG00000179676.6, ENSG00000179818.6, ENSG00000180139.7, ENSG00000180769.4, ENSG00000181171.5, ENSG00000181798.2, ENSG00000184441.4, ENSG00000186056.4, ENSG00000187979.3, ENSG00000188424.4, ENSG00000196096.3, ENSG00000196243.4, ENSG00000196273.3, EN | hsa_circ_000529, hsa_circ_000681 | hepatocellular carcinoma (HCC), down-regulated, microarray, 2006, Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. | hsa-miR-215 | ENSG00000100181.15, ENSG00000124915.6, ENSG00000162947.4, ENSG00000163364.4, ENSG00000167117.3, ENSG00000170846.11, ENSG00000175061.9, ENSG00000175699.8, ENSG00000175701.6, ENSG00000175772.10, ENSG00000176936.2, ENSG00000177640.11, ENSG00000179406.6, ENSG00000179676.6, ENSG00000179818.6, ENSG00000180139.7, ENSG00000180769.4, ENSG00000181171.5, ENSG00000181798.2, ENSG00000184441.4, ENSG00000186056.4, ENSG00000187979.3, ENSG00000188424.4, ENSG00000196096.3, ENSG00000196243.4, ENSG00000196273.3, EN | hsa_circ_000529, hsa_circ_000681 | malignant melanoma, down-regulated, Northern blot, qRT-PCR etc, 2008, MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. | hsa-miR-215 | ENSG00000100181.15, ENSG00000124915.6, ENSG00000162947.4, ENSG00000163364.4, ENSG00000167117.3, ENSG00000170846.11, ENSG00000175061.9, ENSG00000175699.8, ENSG00000175701.6, ENSG00000175772.10, ENSG00000176936.2, ENSG00000177640.11, ENSG00000179406.6, ENSG00000179676.6, ENSG00000179818.6, ENSG00000180139.7, ENSG00000180769.4, ENSG00000181171.5, ENSG00000181798.2, ENSG00000184441.4, ENSG00000186056.4, ENSG00000187979.3, ENSG00000188424.4, ENSG00000196096.3, ENSG00000196243.4, ENSG00000196273.3, EN | hsa_circ_000529, hsa_circ_000681 | malignant melanoma, down-regulated, Northern blot, qRT-PCR etc, 2008, MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. | hsa-miR-326 | ENSG00000089336.6, ENSG00000100181.15, ENSG00000117242.7, ENSG00000124835.2, ENSG00000126005.10, ENSG00000126005.10, ENSG00000131007.5, ENSG00000131009.4, ENSG00000132832.4, ENSG00000132832.4, ENSG00000141028.4, ENSG00000141028.4, ENSG00000145063.9, ENSG00000152931.6, ENSG00000159712.9, ENSG00000161103.6, ENSG00000164621.5, ENSG00000164621.5, ENSG00000167117.3, ENSG00000170846.11, ENSG00000170858.5, ENSG00000170983.3, ENSG00000173811.6, ENSG00000174365.14, ENSG00000174403.11, ENSG00000175061.9, | hsa_circ_000614 | multiple sclerosis, up-regulated, northern blot, qRT-PCR etc, 2009, MicroRNA miR-326 regulates T(H)-17 differentiation and is associated with the pathogenesis of multiple sclerosis | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | myeloproliferative disorder, down-regulated, northern blot, qRT-PCR etc, 2009, Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | primary biliary cirrhosis (PBC), down-regulated, microarray, 2008, WITHDRAWN:MicroRNA profile in peripheral blood T cells of patients with primary biliary cirrhosis. | hsa-miR-326 | ENSG00000089336.6, ENSG00000100181.15, ENSG00000117242.7, ENSG00000124835.2, ENSG00000126005.10, ENSG00000126005.10, ENSG00000131007.5, ENSG00000131009.4, ENSG00000132832.4, ENSG00000132832.4, ENSG00000141028.4, ENSG00000141028.4, ENSG00000145063.9, ENSG00000152931.6, ENSG00000159712.9, ENSG00000161103.6, ENSG00000164621.5, ENSG00000164621.5, ENSG00000167117.3, ENSG00000170846.11, ENSG00000170858.5, ENSG00000170983.3, ENSG00000173811.6, ENSG00000174365.14, ENSG00000174403.11, ENSG00000175061.9, | hsa_circ_000614 | primary biliary cirrhosis (PBC), down-regulated, microarray, 2008, WITHDRAWN:MicroRNA profile in peripheral blood T cells of patients with primary biliary cirrhosis. | hsa-miR-326 | ENSG00000089336.6, ENSG00000100181.15, ENSG00000117242.7, ENSG00000124835.2, ENSG00000126005.10, ENSG00000126005.10, ENSG00000131007.5, ENSG00000131009.4, ENSG00000132832.4, ENSG00000132832.4, ENSG00000141028.4, ENSG00000141028.4, ENSG00000145063.9, ENSG00000152931.6, ENSG00000159712.9, ENSG00000161103.6, ENSG00000164621.5, ENSG00000164621.5, ENSG00000167117.3, ENSG00000170846.11, ENSG00000170858.5, ENSG00000170983.3, ENSG00000173811.6, ENSG00000174365.14, ENSG00000174403.11, ENSG00000175061.9, | hsa_circ_000614 | psoriasis, down-regulated, microarray, 2007, MicroRNAs: novel regulators involved in the pathogenesis of Psoriasis? | hsa-miR-215 | ENSG00000100181.15, ENSG00000124915.6, ENSG00000162947.4, ENSG00000163364.4, ENSG00000167117.3, ENSG00000170846.11, ENSG00000175061.9, ENSG00000175699.8, ENSG00000175701.6, ENSG00000175772.10, ENSG00000176936.2, ENSG00000177640.11, ENSG00000179406.6, ENSG00000179676.6, ENSG00000179818.6, ENSG00000180139.7, ENSG00000180769.4, ENSG00000181171.5, ENSG00000181798.2, ENSG00000184441.4, ENSG00000186056.4, ENSG00000187979.3, ENSG00000188424.4, ENSG00000196096.3, ENSG00000196243.4, ENSG00000196273.3, EN | hsa_circ_000529, hsa_circ_000681 | psoriasis, down-regulated, microarray, 2007, MicroRNAs: novel regulators involved in the pathogenesis of Psoriasis? | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | retinitis pigmentosa (RP), down-regulated, Northern blot, qRT-PCR etc, 2007, Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | tongue squamous cell carcinoma, down-regulated, Northern blot, qRT-PCR etc, 2008, Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling. | hsa-miR-133a | ENSG00000089336.6, ENSG00000152931.6, ENSG00000153363.8, ENSG00000159712.9, ENSG00000161103.6, ENSG00000170846.11, ENSG00000174403.11, ENSG00000175147.7, ENSG00000175611.6, ENSG00000176728.3, ENSG00000177640.11, ENSG00000177699.4, ENSG00000179406.6, ENSG00000179523.4, ENSG00000179935.5, ENSG00000180139.7, ENSG00000180712.3, ENSG00000180910.7, ENSG00000182057.4, ENSG00000182376.2, ENSG00000183016.8, ENSG00000183242.7, ENSG00000183566.5, ENSG00000183674.7, ENSG00000185065.6, ENSG00000186056.4, ENS | hsa_circ_000930, hsa_circ_001923, hsa_circ_001152 | vascular disease, down-regulated, Northern blot, qRT-PCR etc, 2007, MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. | |