Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 1 149939226 149939226 + Silent SNP T T C TCGA-OR-A5K4-01A-11D-A29I-10 TCGA-OR-A5K4-10A-01D-A29L-10 g.chr1:149939226T>C c.495A>G c.(493-495)gaA>gaG p.E165E BLCA 1 149915774 149915774 + Silent SNP G G T TCGA-K4-A5RJ-01A-11D-A289-08 TCGA-K4-A5RJ-10A-01D-A289-08 g.chr1:149915774G>T c.2514C>A c.(2512-2514)ctC>ctA p.L838L BLCA 1 149915893 149915893 + Missense_Mutation SNP G G C TCGA-GV-A6ZA-01A-12D-A339-08 TCGA-GV-A6ZA-10A-01D-A339-08 g.chr1:149915893G>C c.2395C>G c.(2395-2397)Cag>Gag p.Q799E BLCA 1 149915902 149915902 + Missense_Mutation SNP G G A TCGA-GV-A6ZA-01A-12D-A339-08 TCGA-GV-A6ZA-10A-01D-A339-08 g.chr1:149915902G>A c.2386C>T c.(2386-2388)Ccc>Tcc p.P796S BLCA 1 149916075 149916075 + Missense_Mutation SNP C C T TCGA-BT-A20J-01A-11D-A14W-08 TCGA-BT-A20J-11A-11D-A14W-08 g.chr1:149916075C>T c.2213G>A c.(2212-2214)cGa>cAa p.R738Q BLCA 1 149916098 149916098 + Silent SNP G G A TCGA-GU-A764-01A-11D-A34U-08 TCGA-GU-A764-10B-01D-A34X-08 g.chr1:149916098G>A c.2190C>T c.(2188-2190)ttC>ttT p.F730F BLCA 1 149916332 149916332 + Silent SNP G G A TCGA-ZF-AA4W-01A-12D-A38G-08 TCGA-ZF-AA4W-10A-01D-A38J-08 g.chr1:149916332G>A c.1956C>T c.(1954-1956)atC>atT p.I652I BLCA 1 149916353 149916353 + Missense_Mutation SNP C C G TCGA-4Z-AA7M-01A-11D-A391-08 TCGA-4Z-AA7M-10A-01D-A394-08 g.chr1:149916353C>G c.1935G>C c.(1933-1935)caG>caC p.Q645H BLCA 1 149916737 149916737 + Silent SNP G G C TCGA-GU-A764-01A-11D-A34U-08 TCGA-GU-A764-10B-01D-A34X-08 g.chr1:149916737G>C c.1551C>G c.(1549-1551)ctC>ctG p.L517L BLCA 1 149916865 149916865 + Missense_Mutation SNP T T G TCGA-UY-A9PE-01A-11D-A38G-08 TCGA-UY-A9PE-10A-01D-A38J-08 g.chr1:149916865T>G c.1423A>C c.(1423-1425)Agt>Cgt p.S475R BLCA 1 149916953 149916953 + Silent SNP G G C TCGA-DK-AA77-01A-11D-A391-08 TCGA-DK-AA77-10A-01D-A394-08 g.chr1:149916953G>C c.1335C>G c.(1333-1335)gcC>gcG p.A445A BLCA 1 149921589 149921589 + Missense_Mutation SNP G G C TCGA-DK-A2I4-01A-11D-A21A-08 TCGA-DK-A2I4-10A-01D-A21A-08 g.chr1:149921589G>C c.1066C>G c.(1066-1068)Cag>Gag p.Q356E BLCA 1 149921612 149921612 + Missense_Mutation SNP G G T TCGA-DK-A2I4-01A-11D-A21A-08 TCGA-DK-A2I4-10A-01D-A21A-08 g.chr1:149921612G>T c.1043C>A c.(1042-1044)tCc>tAc p.S348Y BLCA 1 149937765 149937765 + Nonsense_Mutation SNP G G A TCGA-XF-A9T8-01A-11D-A391-08 TCGA-XF-A9T8-10A-01D-A394-08 g.chr1:149937765G>A c.541C>T c.(541-543)Cag>Tag p.Q181* BLCA 1 149943009 149943009 + Nonsense_Mutation SNP G G A TCGA-BT-A2LD-01A-12D-A20D-08 TCGA-BT-A2LD-10A-01D-A20D-08 g.chr1:149943009G>A c.256C>T c.(256-258)Cag>Tag p.Q86* BRCA 1 149915938 149915938 + Missense_Mutation SNP C C T TCGA-B6-A400-01A-11D-A23C-09 TCGA-B6-A400-10A-01D-A23C-09 g.chr1:149915938C>T c.2350G>A c.(2350-2352)Gag>Aag p.E784K BRCA 1 149916418 149916418 + Missense_Mutation SNP G G C TCGA-D8-A1JA-01A-11D-A13L-09 TCGA-D8-A1JA-10A-01W-A14R-09 g.chr1:149916418G>C c.1870C>G c.(1870-1872)Cag>Gag p.Q624E BRCA 1 149916432 149916432 + Missense_Mutation SNP T T C TCGA-AN-A046-01A-21W-A050-09 TCGA-AN-A046-10A-01W-A055-09 g.chr1:149916432T>C c.1856A>G c.(1855-1857)cAc>cGc p.H619R BRCA 1 149931697 149931697 + Missense_Mutation SNP C C T TCGA-A8-A090-01A-11W-A019-09 TCGA-A8-A090-10A-01W-A021-09 g.chr1:149931697C>T c.751G>A c.(751-753)Gaa>Aaa p.E251K BRCA 1 149937782 149937782 + Missense_Mutation SNP C C T TCGA-E2-A152-01A-11D-A12B-09 TCGA-E2-A152-10A-01D-A12B-09 g.chr1:149937782C>T c.524G>A c.(523-525)aGt>aAt p.S175N BRCA 1 149939361 149939361 + Silent SNP A A C TCGA-A2-A0T5-01A-21D-A099-09 TCGA-A2-A0T5-10A-01D-A099-09 g.chr1:149939361A>C c.360T>G c.(358-360)ggT>ggG p.G120G BRCA 1 149939361 149939361 + Silent SNP A A C TCGA-A8-A0A6-01A-12W-A071-09 TCGA-A8-A0A6-10A-01W-A071-09 g.chr1:149939361A>C c.360T>G c.(358-360)ggT>ggG p.G120G BRCA 1 149939379 149939379 + Silent SNP G G C TCGA-AC-A23H-01A-11D-A159-09 TCGA-AC-A23H-11A-12D-A17G-09 g.chr1:149939379G>C c.342C>G c.(340-342)gtC>gtG p.V114V BRCA 1 149939428 149939428 + Missense_Mutation SNP C C A TCGA-E2-A155-01A-11D-A12B-09 TCGA-E2-A155-10A-01D-A12B-09 g.chr1:149939428C>A c.293G>T c.(292-294)gGc>gTc p.G98V BRCA 1 149943095 149943095 + Missense_Mutation SNP C C A TCGA-E9-A1RH-01A-21D-A167-09 TCGA-E9-A1RH-10A-01D-A167-09 g.chr1:149943095C>A c.170G>T c.(169-171)aGt>aTt p.S57I BRCA 1 149943110 149943110 + Missense_Mutation SNP A A G TCGA-D8-A1XK-01A-21D-A14K-09 TCGA-D8-A1XK-10A-01D-A14K-09 g.chr1:149943110A>G c.155T>C c.(154-156)cTa>cCa p.L52P CESC 1 149919220 149919220 + Missense_Mutation SNP C C G TCGA-EK-A3GK-01A-11D-A20U-09 TCGA-EK-A3GK-10A-01D-A20U-09 g.chr1:149919220C>G c.1255G>C c.(1255-1257)Gag>Cag p.E419Q CESC 1 149921607 149921607 + Silent SNP G G A TCGA-IR-A3LA-01A-11D-A22X-09 TCGA-IR-A3LA-10A-01D-A22X-09 g.chr1:149921607G>A c.1048C>T c.(1048-1050)Ctg>Ttg p.L350L COAD 1 149915794 149915794 + Missense_Mutation SNP G G A TCGA-G4-6299-01A-11D-1771-10 TCGA-G4-6299-10A-01D-1771-10 g.chr1:149915794G>A c.2494C>T c.(2494-2496)Cgg>Tgg p.R832W COAD 1 149915861 149915861 + Missense_Mutation SNP G G T TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr1:149915861G>T c.2427C>A c.(2425-2427)ttC>ttA p.F809L COAD 1 149916174 149916174 + Missense_Mutation SNP C C A TCGA-A6-6138-01A-11D-1771-10 TCGA-A6-6138-10A-01D-1771-10 g.chr1:149916174C>A c.2114G>T c.(2113-2115)gGa>gTa p.G705V COAD 1 149916814 149916814 + Missense_Mutation SNP G G A TCGA-D5-6529-01A-11D-1771-10 TCGA-D5-6529-10A-01D-1771-10 g.chr1:149916814G>A c.1474C>T c.(1474-1476)Cgg>Tgg p.R492W COAD 1 149916818 149916818 + Silent SNP T T C TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr1:149916818T>C c.1470A>G c.(1468-1470)cgA>cgG p.R490R COAD 1 149931639 149931639 + Missense_Mutation SNP C C T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr1:149931639C>T c.809G>A c.(808-810)cGa>cAa p.R270Q COAD 1 149937711 149937711 + Missense_Mutation SNP C C T TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr1:149937711C>T c.595G>A c.(595-597)Gcc>Acc p.A199T COAD 1 149943015 149943015 + Nonsense_Mutation SNP G G A TCGA-AA-3837-01A-01W-0900-09 TCGA-AA-3837-10A-01W-0900-09 g.chr1:149943015G>A c.250C>T c.(250-252)Cag>Tag p.Q84* COAD 1 149943067 149943067 + Silent SNP A A G TCGA-A6-3809-01A-01W-0995-10 TCGA-A6-3809-11A-01W-0995-10 g.chr1:149943067A>G c.198T>C c.(196-198)ccT>ccC p.P66P COAD 1 149943156 149943156 + Missense_Mutation SNP C C T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr1:149943156C>T c.109G>A c.(109-111)Gcc>Acc p.A37T COADREAD 1 149915794 149915794 + Missense_Mutation SNP G G A TCGA-G4-6299-01A-11D-1771-10 TCGA-G4-6299-10A-01D-1771-10 g.chr1:149915794G>A c.2494C>T c.(2494-2496)Cgg>Tgg p.R832W COADREAD 1 149915861 149915861 + Missense_Mutation SNP G G T TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr1:149915861G>T c.2427C>A c.(2425-2427)ttC>ttA p.F809L COADREAD 1 149916174 149916174 + Missense_Mutation SNP C C A TCGA-A6-6138-01A-11D-1771-10 TCGA-A6-6138-10A-01D-1771-10 g.chr1:149916174C>A c.2114G>T c.(2113-2115)gGa>gTa p.G705V COADREAD 1 149916639 149916639 + Missense_Mutation SNP T T A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr1:149916639T>A c.1649A>T c.(1648-1650)aAg>aTg p.K550M COADREAD 1 149916814 149916814 + Missense_Mutation SNP G G A TCGA-D5-6529-01A-11D-1771-10 TCGA-D5-6529-10A-01D-1771-10 g.chr1:149916814G>A c.1474C>T c.(1474-1476)Cgg>Tgg p.R492W COADREAD 1 149916818 149916818 + Silent SNP T T C TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr1:149916818T>C c.1470A>G c.(1468-1470)cgA>cgG p.R490R COADREAD 1 149922060 149922060 + Missense_Mutation SNP G G A TCGA-AG-A026-01A-32W-A096-10 TCGA-AG-A026-10A-01W-A096-10 g.chr1:149922060G>A c.910C>T c.(910-912)Cat>Tat p.H304Y COADREAD 1 149931639 149931639 + Missense_Mutation SNP C C T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr1:149931639C>T c.809G>A c.(808-810)cGa>cAa p.R270Q COADREAD 1 149936185 149936185 + Missense_Mutation SNP T T C TCGA-AG-3893-01A-01W-1073-09 TCGA-AG-3893-10A-01W-1073-09 g.chr1:149936185T>C c.694A>G c.(694-696)Agg>Ggg p.R232G COADREAD 1 149937711 149937711 + Missense_Mutation SNP C C T TCGA-AZ-4315-01A-01D-1408-10 TCGA-AZ-4315-10A-01D-1408-10 g.chr1:149937711C>T c.595G>A c.(595-597)Gcc>Acc p.A199T COADREAD 1 149943015 149943015 + Nonsense_Mutation SNP G G A TCGA-AA-3837-01A-01W-0900-09 TCGA-AA-3837-10A-01W-0900-09 g.chr1:149943015G>A c.250C>T c.(250-252)Cag>Tag p.Q84* COADREAD 1 149943067 149943067 + Silent SNP A A G TCGA-A6-3809-01A-01W-0995-10 TCGA-A6-3809-11A-01W-0995-10 g.chr1:149943067A>G c.198T>C c.(196-198)ccT>ccC p.P66P COADREAD 1 149943156 149943156 + Missense_Mutation SNP C C T TCGA-AA-A010-01A-01W-A00E-09 TCGA-AA-A010-10A-01W-A00E-09 g.chr1:149943156C>T c.109G>A c.(109-111)Gcc>Acc p.A37T DLBC 1 149916118 149916118 + Missense_Mutation SNP G G C TCGA-G8-6906-01A-11D-2210-10 TCGA-G8-6906-14A-01D-2210-10 g.chr1:149916118G>C c.2170C>G c.(2170-2172)Cta>Gta p.L724V DLBC 1 149916584 149916584 + Silent SNP C C G TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr1:149916584C>G c.1704G>C c.(1702-1704)ggG>ggC p.G568G ESCA 1 149915980 149915980 + Nonsense_Mutation SNP G G A TCGA-L5-A8NR-01A-11D-A37C-09 TCGA-L5-A8NR-11A-11D-A37F-09 g.chr1:149915980G>A c.2308C>T c.(2308-2310)Cga>Tga p.R770* ESCA 1 149916658 149916658 + Missense_Mutation SNP C C T TCGA-IG-A3YA-01A-11D-A247-09 TCGA-IG-A3YA-10A-01D-A247-09 g.chr1:149916658C>T c.1630G>A c.(1630-1632)Ggc>Agc p.G544S ESCA 1 149921626 149921626 + Missense_Mutation SNP G G T TCGA-L7-A6VZ-01A-12D-A33E-09 TCGA-L7-A6VZ-10A-01D-A33H-09 g.chr1:149921626G>T c.1029C>A c.(1027-1029)agC>agA p.S343R ESCA 1 149922096 149922096 + Nonsense_Mutation SNP C C A TCGA-L5-A8NK-01A-21D-A37C-09 TCGA-L5-A8NK-11A-11D-A37F-09 g.chr1:149922096C>A c.874G>T c.(874-876)Gag>Tag p.E292* ESCA 1 149931714 149931714 + Splice_Site SNP G G A TCGA-V5-A7RC-01B-11D-A403-09 TCGA-V5-A7RC-10A-01D-A403-09 g.chr1:149931714G>A c.734C>T c.(733-735)tCa>tTa p.S245L ESCA 1 149936185 149936185 + Frame_Shift_Del DEL T T - TCGA-JY-A6F8-01A-11D-A33E-09 TCGA-JY-A6F8-10A-01D-A33H-09 g.chr1:149936185delT c.694delA c.(694-696)aggfs p.R233fs ESCA 1 149936187 149936187 + Missense_Mutation SNP T T C TCGA-L5-A8NM-01A-11D-A37C-09 TCGA-L5-A8NM-11A-12D-A37F-09 g.chr1:149936187T>C c.692A>G c.(691-693)aAa>aGa p.K231R ESCA 1 149936261 149936261 + Missense_Mutation SNP G G T TCGA-JY-A6F8-01A-11D-A33E-09 TCGA-JY-A6F8-10A-01D-A33H-09 g.chr1:149936261G>T c.618C>A c.(616-618)ttC>ttA p.F206L ESCA 1 149949403 149949403 + Missense_Mutation SNP A A G TCGA-L5-A8NM-01A-11D-A37C-09 TCGA-L5-A8NM-11A-12D-A37F-09 g.chr1:149949403A>G c.43T>C c.(43-45)Tcc>Ccc p.S15P GBMLGG 1 149916850 149916850 + Missense_Mutation SNP C C T TCGA-HT-A5RC-01A-11D-A289-08 TCGA-HT-A5RC-10A-01D-A289-08 g.chr1:149916850C>T c.1438G>A c.(1438-1440)Gag>Aag p.E480K GBMLGG 1 149919215 149919215 + Silent SNP G G A TCGA-TQ-A7RM-01A-11D-A33T-08 TCGA-TQ-A7RM-10A-01D-A33W-08 g.chr1:149919215G>A c.1260C>T c.(1258-1260)gtC>gtT p.V420V HNSC 1 149915890 149915890 + Missense_Mutation SNP T T A TCGA-CN-4739-01A-02D-1512-08 TCGA-CN-4739-10A-01D-1512-08 g.chr1:149915890T>A c.2398A>T c.(2398-2400)Acc>Tcc p.T800S HNSC 1 149915899 149915899 + Missense_Mutation SNP G G C TCGA-CN-A641-01A-11D-A30E-08 TCGA-CN-A641-10A-01D-A30H-08 g.chr1:149915899G>C c.2389C>G c.(2389-2391)Cca>Gca p.P797A HNSC 1 149916210 149916210 + Missense_Mutation SNP G G C TCGA-QK-A6IH-01A-11D-A31L-08 TCGA-QK-A6IH-10A-01D-A31J-08 g.chr1:149916210G>C c.2078C>G c.(2077-2079)cCt>cGt p.P693R HNSC 1 149916498 149916498 + Missense_Mutation SNP C C T TCGA-CR-7398-01A-11D-2012-08 TCGA-CR-7398-10A-01D-2013-08 g.chr1:149916498C>T c.1790G>A c.(1789-1791)aGc>aAc p.S597N HNSC 1 149916876 149916876 + Nonsense_Mutation SNP G G C TCGA-CN-A6V1-01A-12D-A34J-08 TCGA-CN-A6V1-10B-01D-A34M-08 g.chr1:149916876G>C c.1412C>G c.(1411-1413)tCa>tGa p.S471* HNSC 1 149939440 149939440 + Missense_Mutation SNP C C T TCGA-QK-A8Z8-01A-11D-A391-08 TCGA-QK-A8Z8-10A-01D-A394-08 g.chr1:149939440C>T c.281G>A c.(280-282)cGc>cAc p.R94H KIPAN 1 149916007 149916007 + Missense_Mutation SNP T T C TCGA-SX-A7SU-01A-11D-A35Z-10 TCGA-SX-A7SU-10A-01D-A35Z-10 g.chr1:149916007T>C c.2281A>G c.(2281-2283)Agg>Ggg p.R761G KIPAN 1 149920957 149920957 + Silent SNP A A G TCGA-BP-5189-01A-02D-1429-08 TCGA-BP-5189-11A-01D-1429-08 g.chr1:149920957A>G c.1152T>C c.(1150-1152)taT>taC p.Y384Y KIPAN 1 149920966 149920966 + Silent SNP A A G TCGA-B8-5163-01A-01D-1421-08 TCGA-B8-5163-10A-01D-1421-08 g.chr1:149920966A>G c.1143T>C c.(1141-1143)gaT>gaC p.D381D KIPAN 1 149921598 149921598 + Missense_Mutation SNP C C T TCGA-B0-4828-01A-01D-1361-10 TCGA-B0-4828-11A-01D-1361-10 g.chr1:149921598C>T c.1057G>A c.(1057-1059)Gcc>Acc p.A353T KIRC 1 149920957 149920957 + Silent SNP A A G TCGA-BP-5189-01A-02D-1429-08 TCGA-BP-5189-11A-01D-1429-08 g.chr1:149920957A>G c.1152T>C c.(1150-1152)taT>taC p.Y384Y KIRC 1 149920966 149920966 + Silent SNP A A G TCGA-B8-5163-01A-01D-1421-08 TCGA-B8-5163-10A-01D-1421-08 g.chr1:149920966A>G c.1143T>C c.(1141-1143)gaT>gaC p.D381D KIRC 1 149921598 149921598 + Missense_Mutation SNP C C T TCGA-B0-4828-01A-01D-1361-10 TCGA-B0-4828-11A-01D-1361-10 g.chr1:149921598C>T c.1057G>A c.(1057-1059)Gcc>Acc p.A353T KIRP 1 149916007 149916007 + Missense_Mutation SNP T T C TCGA-SX-A7SU-01A-11D-A35Z-10 TCGA-SX-A7SU-10A-01D-A35Z-10 g.chr1:149916007T>C c.2281A>G c.(2281-2283)Agg>Ggg p.R761G LGG 1 149916850 149916850 + Missense_Mutation SNP C C T TCGA-HT-A5RC-01A-11D-A289-08 TCGA-HT-A5RC-10A-01D-A289-08 g.chr1:149916850C>T c.1438G>A c.(1438-1440)Gag>Aag p.E480K LGG 1 149919215 149919215 + Silent SNP G G A TCGA-TQ-A7RM-01A-11D-A33T-08 TCGA-TQ-A7RM-10A-01D-A33W-08 g.chr1:149919215G>A c.1260C>T c.(1258-1260)gtC>gtT p.V420V LIHC 1 149915759 149915759 + Silent SNP G G A TCGA-DD-A4NV-01A-11D-A30V-10 TCGA-DD-A4NV-10A-01D-A30V-10 g.chr1:149915759G>A c.2529C>T c.(2527-2529)ttC>ttT p.F843F LIHC 1 149916120 149916120 + Missense_Mutation SNP C C A TCGA-CC-5258-01A-01D-A12Z-10 TCGA-CC-5258-10A-01D-A12Z-10 g.chr1:149916120C>A c.2168G>T c.(2167-2169)gGc>gTc p.G723V LIHC 1 149922079 149922079 + Frame_Shift_Del DEL A A - TCGA-DD-A1EG-01A-11D-A20W-10 TCGA-DD-A1EG-10A-01D-A20W-10 g.chr1:149922079delA c.891delT c.(889-891)tttfs p.F297fs LIHC 1 149936173 149936173 + Missense_Mutation SNP A A G TCGA-G3-A3CJ-01A-11D-A20W-10 TCGA-G3-A3CJ-10A-01D-A20W-10 g.chr1:149936173A>G c.706T>C c.(706-708)Tgg>Cgg p.W236R LUAD 1 149915757 149915757 + Nonstop_Mutation SNP C C A TCGA-55-8205-01A-11D-2238-08 TCGA-55-8205-10A-01D-2238-08 g.chr1:149915757C>A c.2531G>T c.(2530-2532)tGa>tTa p.*844L LUAD 1 149915923 149915923 + Missense_Mutation SNP C C A TCGA-05-4397-01A-01D-1265-08 TCGA-05-4397-10A-01D-1265-08 g.chr1:149915923C>A c.2365G>T c.(2365-2367)Gct>Tct p.A789S LUAD 1 149916177 149916177 + Frame_Shift_Del DEL C C - TCGA-55-1595-01A-01D-0969-08 TCGA-55-1595-11A-01D-0969-08 g.chr1:149916177delC c.2111delG c.(2110-2112)ggcfs p.G705fs LUAD 1 149916181 149916181 + Missense_Mutation SNP C C A TCGA-55-7994-01A-11D-2184-08 TCGA-55-7994-10A-01D-2184-08 g.chr1:149916181C>A c.2107G>T c.(2107-2109)Ggg>Tgg p.G703W LUAD 1 149916312 149916312 + Missense_Mutation SNP C C A TCGA-05-4382-01A-01D-1931-08 TCGA-05-4382-10A-01D-1265-08 g.chr1:149916312C>A c.1976G>T c.(1975-1977)gGt>gTt p.G659V LUAD 1 149916620 149916620 + Silent SNP C C G TCGA-86-8673-01A-11D-2393-08 TCGA-86-8673-10A-01D-2393-08 g.chr1:149916620C>G c.1668G>C c.(1666-1668)ctG>ctC p.L556L LUAD 1 149919162 149919162 + Missense_Mutation SNP G G A TCGA-38-4629-01A-02D-1265-08 TCGA-38-4629-11A-01D-1265-08 g.chr1:149919162G>A c.1313C>T c.(1312-1314)tCt>tTt p.S438F LUAD 1 149919237 149919237 + Splice_Site SNP C C A TCGA-95-A4VK-01A-11D-A25L-08 TCGA-95-A4VK-10A-01D-A25L-08 g.chr1:149919237C>A c.e11-1 LUAD 1 149921568 149921568 + Missense_Mutation SNP C C A TCGA-99-8032-01A-11D-2238-08 TCGA-99-8032-10A-01D-2238-08 g.chr1:149921568C>A c.1087G>T c.(1087-1089)Gtg>Ttg p.V363L LUAD 1 149921592 149921592 + Missense_Mutation SNP C C G TCGA-44-7670-01A-11D-2063-08 TCGA-44-7670-10A-01D-2063-08 g.chr1:149921592C>G c.1063G>C c.(1063-1065)Gat>Cat p.D355H LUAD 1 149936222 149936222 + Silent SNP T T C TCGA-49-4510-01A-01D-1265-08 TCGA-49-4510-11A-01D-1265-08 g.chr1:149936222T>C c.657A>G c.(655-657)gcA>gcG p.A219A LUAD 1 149936267 149936267 + Missense_Mutation SNP C C A TCGA-44-6144-01A-11D-1753-08 TCGA-44-6144-10A-01D-1753-08 g.chr1:149936267C>A c.612G>T c.(610-612)tgG>tgT p.W204C LUAD 1 149943016 149943016 + Silent SNP G G C TCGA-55-6968-01A-11D-1945-08 TCGA-55-6968-11A-01D-1945-08 g.chr1:149943016G>C c.249C>G c.(247-249)ctC>ctG p.L83L LUAD 1 149943104 149943104 + Missense_Mutation SNP G G T TCGA-17-Z026-01A-01W-0746-08 TCGA-17-Z026-11A-01W-0746-08 g.chr1:149943104G>T c.161C>A c.(160-162)cCa>cAa p.P54Q LUAD 1 149943154 149943154 + Silent SNP G G A TCGA-17-Z043-01A-01W-0746-08 TCGA-17-Z043-11A-01W-0746-08 g.chr1:149943154G>A c.111C>T c.(109-111)gcC>gcT p.A37A LUSC 1 149916189 149916189 + Missense_Mutation SNP C C T TCGA-66-2754-01A-01D-0983-08 TCGA-66-2754-11A-01D-0983-08 g.chr1:149916189C>T c.2099G>A c.(2098-2100)cGg>cAg p.R700Q LUSC 1 149916922 149916922 + Missense_Mutation SNP C C G TCGA-66-2727-01A-01D-0983-08 TCGA-66-2727-11A-01D-0983-08 g.chr1:149916922C>G c.1366G>C c.(1366-1368)Gat>Cat p.D456H LUSC 1 149931639 149931639 + Missense_Mutation SNP C C T TCGA-66-2773-01A-01D-1267-08 TCGA-66-2773-11A-01D-1267-08 g.chr1:149931639C>T c.809G>A c.(808-810)cGa>cAa p.R270Q LUSC 1 149943093 149943093 + Missense_Mutation SNP C C G TCGA-33-4566-01A-01D-1441-08 TCGA-33-4566-11A-01D-1441-08 g.chr1:149943093C>G c.172G>C c.(172-174)Gag>Cag p.E58Q OV 1 149936182 149936182 + Missense_Mutation SNP G G A TCGA-04-1655-01A-01W-0633-09 TCGA-04-1655-10A-01W-0633-09 g.chr1:149936182G>A c.697C>T c.(697-699)Cgc>Tgc p.R233C PAAD 1 149916165 149916165 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr1:149916165C>T c.2123G>A c.(2122-2124)tGc>tAc p.C708Y PAAD 1 149916371 149916371 + Silent SNP G G A TCGA-LB-A7SX-01A-11D-A33T-08 TCGA-LB-A7SX-10A-01D-A33W-08 g.chr1:149916371G>A c.1917C>T c.(1915-1917)ttC>ttT p.F639F PAAD 1 149920861 149920869 + Splice_Site DEL CCTGGCTTA CCTGGCTTA - TCGA-HZ-7918-01A-11D-2154-08 TCGA-HZ-7918-10A-01D-2154-08 g.chr1:149920861_149920869delCCTGGCTTA c.e10+1 PAAD 1 149939346 149939346 + Missense_Mutation SNP C C A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr1:149939346C>A c.375G>T c.(373-375)gaG>gaT p.E125D PAAD 1 149939428 149939428 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr1:149939428C>T c.293G>A c.(292-294)gGc>gAc p.G98D PRAD 1 149916659 149916659 + Silent SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr1:149916659G>A c.1629C>T c.(1627-1629)agC>agT p.S543S READ 1 149916639 149916639 + Missense_Mutation SNP T T A TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr1:149916639T>A c.1649A>T c.(1648-1650)aAg>aTg p.K550M READ 1 149922060 149922060 + Missense_Mutation SNP G G A TCGA-AG-A026-01A-32W-A096-10 TCGA-AG-A026-10A-01W-A096-10 g.chr1:149922060G>A c.910C>T c.(910-912)Cat>Tat p.H304Y READ 1 149936185 149936185 + Missense_Mutation SNP T T C TCGA-AG-3893-01A-01W-1073-09 TCGA-AG-3893-10A-01W-1073-09 g.chr1:149936185T>C c.694A>G c.(694-696)Agg>Ggg p.R232G SARC 1 149939398 149939398 + Missense_Mutation SNP G G A TCGA-DX-A8BP-01A-11D-A37C-09 TCGA-DX-A8BP-10A-01D-A37F-09 g.chr1:149939398G>A c.323C>T c.(322-324)tCc>tTc p.S108F SKCM 1 149915902 149915902 + Missense_Mutation SNP G G A TCGA-D3-A5GO-06A-12D-A27K-08 TCGA-D3-A5GO-10A-01D-A27N-08 g.chr1:149915902G>A c.2386C>T c.(2386-2388)Ccc>Tcc p.P796S SKCM 1 149915967 149915967 + Missense_Mutation SNP G G A TCGA-EB-A5UL-06A-11D-A30X-08 TCGA-EB-A5UL-10A-01D-A30X-08 g.chr1:149915967G>A c.2321C>T c.(2320-2322)tCc>tTc p.S774F SKCM 1 149916067 149916067 + Missense_Mutation SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr1:149916067G>A c.2221C>T c.(2221-2223)Ccc>Tcc p.P741S SKCM 1 149916096 149916096 + Missense_Mutation SNP G G A TCGA-FS-A1ZW-06A-12D-A197-08 TCGA-FS-A1ZW-10A-01D-A199-08 g.chr1:149916096G>A c.2192C>T c.(2191-2193)cCc>cTc p.P731L SKCM 1 149916222 149916222 + Missense_Mutation SNP G G A TCGA-EE-A2MF-06A-11D-A21A-08 TCGA-EE-A2MF-10B-01D-A21A-08 g.chr1:149916222G>A c.2066C>T c.(2065-2067)tCc>tTc p.S689F SKCM 1 149916304 149916304 + Missense_Mutation SNP G G A TCGA-EE-A181-06A-11D-A196-08 TCGA-EE-A181-10A-01D-A198-08 g.chr1:149916304G>A c.1984C>T c.(1984-1986)Cct>Tct p.P662S SKCM 1 149916786 149916786 + Missense_Mutation SNP G G A TCGA-EE-A3J5-06A-11D-A20D-08 TCGA-EE-A3J5-10A-01D-A20D-08 g.chr1:149916786G>A c.1502C>T c.(1501-1503)tCt>tTt p.S501F SKCM 1 149916792 149916792 + Missense_Mutation SNP G G T TCGA-ER-A19P-06A-11D-A196-08 TCGA-ER-A19P-10A-01D-A198-08 g.chr1:149916792G>T c.1496C>A c.(1495-1497)gCa>gAa p.A499E SKCM 1 149939341 149939341 + Missense_Mutation SNP G G A TCGA-EE-A2MM-06A-11D-A196-08 TCGA-EE-A2MM-10A-01D-A198-08 g.chr1:149939341G>A c.380C>T c.(379-381)cCc>cTc p.P127L SKCM 1 149939342 149939342 + Missense_Mutation SNP G G A TCGA-EE-A2MM-06A-11D-A196-08 TCGA-EE-A2MM-10A-01D-A198-08 g.chr1:149939342G>A c.379C>T c.(379-381)Ccc>Tcc p.P127S SKCM 1 149942998 149942998 + Silent SNP G G A TCGA-EE-A182-06A-11D-A196-08 TCGA-EE-A182-10A-01D-A198-08 g.chr1:149942998G>A c.267C>T c.(265-267)atC>atT p.I89I SKCM 1 149943100 149943100 + Silent SNP G G A TCGA-EE-A29D-06A-11D-A197-08 TCGA-EE-A29D-10A-01D-A199-08 g.chr1:149943100G>A c.165C>T c.(163-165)tcC>tcT p.S55S

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand HN_00076 COSM121449 c.783G>C p.L261L Substitution - coding silent 1:149959746-149959746 - H460 COSM1196956 c.2378G>A p.R793Q Substitution - Missense 1:149944011-149944011 - PT31 COSM2181669 c.2321C>T p.S774F Substitution - Missense 1:149944068-149944068 - TCGA-A5-A0G5-01 COSM895441 c.1358C>G p.S453* Substitution - Nonsense 1:149945031-149945031 - D28 COSM5545524 c.1355C>T p.A452V Substitution - Missense 1:149945034-149945034 - TCGA-AA-3672-01 COSM2181723 c.366delG p.S123fs*29 Deletion - Frameshift 1:149967430-149967430 - 2492701 COSM5716653 c.232C>T p.P78S Substitution - Missense 1:149971105-149971105 - CSCC-40-T COSM4450134 c.460_461delGA p.D154fs*3 Deletion - Frameshift 1:149967335-149967336 - CSCC-16-T COSM4478034 c.2204C>T p.P735L Substitution - Missense 1:149944185-149944185 - TCGA-HF-7132-01 COSM4021922 c.10G>A p.D4N Substitution - Missense 1:149977501-149977501 - 2492709 COSM5716912 c.2206C>T p.P736S Substitution - Missense 1:149944183-149944183 - TCGA-E2-A155-01 COSM423753 c.293G>T p.G98V Substitution - Missense 1:149967503-149967503 - TCGA-EM-A3O3-01 COSM3369266 c.246C>T p.I82I Substitution - coding silent 1:149971091-149971091 - TCGA-AX-A0J1-01 COSM895433 c.2486G>T p.R829M Substitution - Missense 1:149943903-149943903 - TCGA-BS-A0UF-01 COSM895443 c.778G>T p.E260* Substitution - Nonsense 1:149959751-149959751 - 1_PRE-TREATMENT COSM1719836 c.2222C>T p.P741L Substitution - Missense 1:149944167-149944167 - CSB1 COSM5025342 c.892C>T p.H298Y Substitution - Missense 1:149950175-149950175 - ESCC-248T COSM3934073 c.2431G>A p.G811R Substitution - Missense 1:149943958-149943958 - TCGA-DK-A2I4-01 COSM3788632 c.1066C>G p.Q356E Substitution - Missense 1:149949686-149949686 - TCGA-E9-A1RH-01 COSM1472568 c.170G>T p.S57I Substitution - Missense 1:149971167-149971167 - SW620 COSM1667903 c.95G>A p.W32* Substitution - Nonsense 1:149971242-149971242 - LOVO COSM2181724 c.359_360insG p.G121fs*5 Insertion - Frameshift 1:149967436-149967437 - SNU-C2B COSM2181706 c.964G>A p.G322R Substitution - Missense 1:149950103-149950103 - TCGA-EE-A182-06 COSM2181728 c.267C>T p.I89I Substitution - coding silent 1:149971070-149971070 - TCGA-BP-5189-01 COSM462895 c.1152T>C p.Y384Y Substitution - coding silent 1:149949055-149949055 - T578 COSM675589 c.809G>A p.R270Q Substitution - Missense 1:149959720-149959720 - BK0025 COSM4186460 c.2467T>A p.Y823N Substitution - Missense 1:149943922-149943922 - TCGA-HT-A5RC-01 COSM3965788 c.1438G>A p.E480K Substitution - Missense 1:149944951-149944951 - 25T COSM3711131 c.342C>A p.V114V Substitution - coding silent 1:149967454-149967454 - T1 COSM5617598 c.686C>T p.A229V Substitution - Missense 1:149964268-149964268 - Gp2D COSM4626828 c.1839A>T p.G613G Substitution - coding silent 1:149944550-149944550 - TCGA-BR-4280-01 COSM4021917 c.1495G>A p.A499T Substitution - Missense 1:149944894-149944894 - CSCC-47-T COSM4527835 c.1493G>A p.R498K Substitution - Missense 1:149944896-149944896 - 46M COSM5588554 c.2110G>A p.G704S Substitution - Missense 1:149944279-149944279 - ESCC_BICR_036T COSM5432033 c.530A>G p.D177G Substitution - Missense 1:149965851-149965851 - HCT-15 COSM1667901 c.937G>A p.V313M Substitution - Missense 1:149950130-149950130 - TCGA-D1-A17R-01 COSM895445 c.134G>A p.R45H Substitution - Missense 1:149971203-149971203 - 2492702 COSM5716653 c.232C>T p.P78S Substitution - Missense 1:149971105-149971105 - YUPTER COSM5377542 c.231C>T p.R77R Substitution - coding silent 1:149971106-149971106 - Pat_41_B COSM5843521 c.1973G>A p.G658E Substitution - Missense 1:149944416-149944416 - TCGA-AZ-4315-01 COSM1333764 c.2427C>A p.F809L Substitution - Missense 1:149943962-149943962 - LC_C9 COSM1185581 c.2046G>C p.E682D Substitution - Missense 1:149944343-149944343 - TCGA-AZ-6598-01 COSM2181686 c.1568delG p.G523fs*2 Deletion - Frameshift 1:149944821-149944821 - PD6719a COSM5778743 c.2103G>A p.P701P Substitution - coding silent 1:149944286-149944286 - TCGA-AP-A051-01 COSM895437 c.2008G>A p.D670N Substitution - Missense 1:149944381-149944381 - TCGA-FW-A3R5-06 COSM3862626 c.2221C>T p.P741S Substitution - Missense 1:149944168-149944168 - 1320T COSM5762764 c.898T>A p.F300I Substitution - Missense 1:149950169-149950169 - PD5925a COSM5788337 c.1636G>A p.E546K Substitution - Missense 1:149944753-149944753 - 8057649 COSM3385142 c.1611A>G p.T537T Substitution - coding silent 1:149944778-149944778 - OVCAR-5 COSM1683784 c.1646_1648delAGA p.K553delK Deletion - In frame 1:149944741-149944743 - T4 COSM5341541 c.1239-4A>G p.? Unknown 1:149947339-149947339 - TCGA-IR-A3LA-01 COSM4844607 c.1048C>T p.L350L Substitution - coding silent 1:149949704-149949704 - 2492708 COSM5716912 c.2206C>T p.P736S Substitution - Missense 1:149944183-149944183 - TCGA-A8-A090-01 COSM423751 c.751G>A p.E251K Substitution - Missense 1:149959778-149959778 - PT37 COSM5917332 c.1711C>T p.P571S Substitution - Missense 1:149944678-149944678 - TCGA-D1-A103-01 COSM895436 c.2113G>A p.G705R Substitution - Missense 1:149944276-149944276 - TCGA-A6-2686-01 COSM5083911 c.2183C>T p.A728V Substitution - Missense 1:149944206-149944206 - TCGA-D8-A1XK-01 COSM3801721 c.155T>C p.L52P Substitution - Missense 1:149971182-149971182 - pfg043T COSM4762509 c.1624A>C p.S542R Substitution - Missense 1:149944765-149944765 - TCGA-EB-A5UL-06 COSM2181669 c.2321C>T p.S774F Substitution - Missense 1:149944068-149944068 - TCGA-AP-A0LD-01 COSM895440 c.1450C>T p.R484W Substitution - Missense 1:149944939-149944939 - TCGA-EB-A44P-01 COSM3473322 c.2111G>C p.G704A Substitution - Missense 1:149944278-149944278 - TCGA-D3-A5GO-06 COSM3473320 c.2386C>T p.P796S Substitution - Missense 1:149944003-149944003 - S37_pre COSM5574843 c.1676G>A p.W559* Substitution - Nonsense 1:149944713-149944713 - RKO COSM2181670 c.2304delC p.Y769fs*59 Deletion - Frameshift 1:149944085-149944085 - TCGA-AZ-4315-01 COSM1333768 c.595G>A p.A199T Substitution - Missense 1:149965786-149965786 - ESO-139 COSM1260734 c.1694A>G p.E565G Substitution - Missense 1:149944695-149944695 - TCGA-AA-A010-01 COSM283660 c.109G>A p.A37T Substitution - Missense 1:149971228-149971228 - HCT15 COSM1667901 c.937G>A p.V313M Substitution - Missense 1:149950130-149950130 - TCGA-AY-4070-01 COSM5135868 c.2193C>A p.P731P Substitution - coding silent 1:149944196-149944196 - NCI-ADR-RES COSM1683784 c.1646_1648delAGA p.K553delK Deletion - In frame 1:149944741-149944743 - TCGA-AG-A002-01 COSM262704 c.1649A>T p.K550M Substitution - Missense 1:149944740-149944740 - CSCC-41-T COSM4565420 c.2094_2095CC>TT p.P699S Substitution - Missense 1:149944294-149944295 - TCGA-D1-A17Q-01 COSM895435 c.2167G>A p.G723S Substitution - Missense 1:149944222-149944222 - 8067240 COSM3771438 c.212C>T p.S71F Substitution - Missense 1:149971125-149971125 - CSCC-29-T COSM3771438 c.212C>T p.S71F Substitution - Missense 1:149971125-149971125 - TCGA-CK-4951-01 COSM5146771 c.73G>A p.D25N Substitution - Missense 1:149977438-149977438 - TCGA-FS-A1ZW-06 COSM3473321 c.2192C>T p.P731L Substitution - Missense 1:149944197-149944197 - TCGA-AN-A046-01 COSM3801718 c.1856A>G p.H619R Substitution - Missense 1:149944533-149944533 - S02285 COSM5684306 c.566C>T p.T189I Substitution - Missense 1:149965815-149965815 - 2492700 COSM5716653 c.232C>T p.P78S Substitution - Missense 1:149971105-149971105 - SK-MEL-5 COSM1667902 c.133C>T p.R45C Substitution - Missense 1:149971204-149971204 - TCGA-HU-A4H3-01 COSM4021916 c.1630G>A p.G544S Substitution - Missense 1:149944759-149944759 - TCGA-G4-6299-01 COSM1219007 c.2494C>T p.R832W Substitution - Missense 1:149943895-149943895 - TCGA-04-1655-01 COSM1320014 c.697C>T p.R233C Substitution - Missense 1:149964257-149964257 - ccRCC-14 COSM1663298 c.1916T>A p.F639Y Substitution - Missense 1:149944473-149944473 - TCGA-D5-6529-01 COSM1333766 c.1474C>T p.R492W Substitution - Missense 1:149944915-149944915 - CRC-18T COSM2181705 c.973+1G>A p.? Unknown 1:149950093-149950093 - TCGA-D1-A174-01 COSM895438 c.1952A>C p.K651T Substitution - Missense 1:149944437-149944437 - TCGA-IH-A3EA-01 COSM3862627 c.553C>T p.P185S Substitution - Missense 1:149965828-149965828 - 12820 COSM5613749 c.1702G>T p.G568W Substitution - Missense 1:149944687-149944687 - TCGA-BS-A0TA-01 COSM895442 c.1039C>T p.R347C Substitution - Missense 1:149949713-149949713 - LUAD-FH5PJ COSM403914 c.396C>T p.I132I Substitution - coding silent 1:149967400-149967400 - B COSM3728461 c.85G>T p.G29* Substitution - Nonsense 1:149977426-149977426 - Pat_41_B COSM5843523 c.1360G>A p.A454T Substitution - Missense 1:149945029-149945029 - T276 COSM4710586 c.505C>T p.R169C Substitution - Missense 1:149965876-149965876 - T3118 COSM2181694 c.1354G>A p.A452T Substitution - Missense 1:149945035-149945035 - SJHGG037_D COSM4970768 c.1967G>A p.G656E Substitution - Missense 1:149944422-149944422 - TCGA-AG-3893-01 COSM258574 c.694A>G p.R232G Substitution - Missense 1:149964260-149964260 - HN_62532 COSM126855 c.874G>T p.E292* Substitution - Nonsense 1:149950193-149950193 - TCGA-A2-A0T5-01 COSM3801719 c.360T>G p.G120G Substitution - coding silent 1:149967436-149967436 - Gp5D COSM2181712 c.869T>C p.V290A Substitution - Missense 1:149950198-149950198 - RKO COSM4647328 c.1288A>G p.N430D Substitution - Missense 1:149947286-149947286 - 2492710 COSM5716912 c.2206C>T p.P736S Substitution - Missense 1:149944183-149944183 - 134413 COSM326049 c.1048C>G p.L350V Substitution - Missense 1:149949704-149949704 - 260211 COSM3725518 c.1585G>T p.G529C Substitution - Missense 1:149944804-149944804 - TCGA-E2-A152-01 COSM423752 c.524G>A p.S175N Substitution - Missense 1:149965857-149965857 - YUJUBE COSM5377541 c.1385C>T p.P462L Substitution - Missense 1:149945004-149945004 - 0070_CRUK_PC_0070_T1_DNA COSM1320014 c.697C>T p.R233C Substitution - Missense 1:149964257-149964257 - CCK81 COSM2181729 c.254G>A p.R85Q Substitution - Missense 1:149971083-149971083 - S00838 COSM5661323 c.2264C>T p.S755F Substitution - Missense 1:149944125-149944125 - TCGA-66-2773-01 COSM675589 c.809G>A p.R270Q Substitution - Missense 1:149959720-149959720 - SNU-C2B COSM2181679 c.1962T>C p.N654N Substitution - coding silent 1:149944427-149944427 - TCGA-AC-A23H-01 COSM3801720 c.342C>G p.V114V Substitution - coding silent 1:149967454-149967454 - T3351 COSM4710588 c.194C>T p.T65I Substitution - Missense 1:149971143-149971143 - TCGA-D8-A1JA-01 COSM3801717 c.1870C>G p.Q624E Substitution - Missense 1:149944519-149944519 - TCGA-66-2727-01 COSM675590 c.1366G>C p.D456H Substitution - Missense 1:149945023-149945023 - Pat_26_A COSM5843522 c.1551_1552delCA p.K518fs*28 Deletion - Frameshift 1:149944837-149944838 - TCGA-BR-4368-01 COSM4021920 c.280C>T p.R94C Substitution - Missense 1:149967516-149967516 - CSCC-11-T COSM3473324 c.1502C>T p.S501F Substitution - Missense 1:149944887-149944887 - S37_post COSM5574843 c.1676G>A p.W559* Substitution - Nonsense 1:149944713-149944713 - RK184_C01 COSM1626395 c.1246C>A p.L416M Substitution - Missense 1:149947328-149947328 - TCGA-D1-A167-01 COSM895434 c.2377C>T p.R793W Substitution - Missense 1:149944012-149944012 - STC297 COSM5052521 c.1086C>T p.L362L Substitution - coding silent 1:149949666-149949666 - Pat_06_A COSM5843525 c.68C>T p.A23V Substitution - Missense 1:149977443-149977443 - LUAD-RT-S01810 COSM382750 c.182G>A p.G61D Substitution - Missense 1:149971155-149971155 - RK180_C01 COSM1626396 c.326T>C p.L109P Substitution - Missense 1:149967470-149967470 - SC_9109 COSM5568538 c.1629C>T p.S543S Substitution - coding silent 1:149944760-149944760 - TCGA-BT-A20J-01 COSM414093 c.2213G>A p.R738Q Substitution - Missense 1:149944176-149944176 - OVCAR-8 COSM1683784 c.1646_1648delAGA p.K553delK Deletion - In frame 1:149944741-149944743 - TCGA-CK-5916-01 COSM1333767 c.1470A>G p.R490R Substitution - coding silent 1:149944919-149944919 - CWR22 COSM238544 c.1352delC p.A452fs*73 Deletion - Frameshift 1:149945037-149945037 - HT29 COSM2181734 c.93T>C p.N31N Substitution - coding silent 1:149971244-149971244 - TCGA-66-2754-01 COSM675591 c.2099G>A p.R700Q Substitution - Missense 1:149944290-149944290 - TCGA-AA-3837-01 COSM271679 c.250C>T p.Q84* Substitution - Nonsense 1:149971087-149971087 - Pat_14_A COSM3862627 c.553C>T p.P185S Substitution - Missense 1:149965828-149965828 - TCGA-EE-A29D-06 COSM3473327 c.165C>T p.S55S Substitution - coding silent 1:149971172-149971172 - CSCC-31-T COSM4514922 c.990C>T p.P330P Substitution - coding silent 1:149949762-149949762 - TCGA-EE-A3J5-06 COSM3473324 c.1502C>T p.S501F Substitution - Missense 1:149944887-149944887 - TCGA-B0-4828-01 COSM3360308 c.1057G>A p.A353T Substitution - Missense 1:149949695-149949695 - TCGA-CA-6717-01 COSM675589 c.809G>A p.R270Q Substitution - Missense 1:149959720-149959720 - TCGA-AZ-6601-01 COSM5142068 c.86-7C>A p.? Unknown 1:149971258-149971258 - S00934 COSM5662596 c.705G>T p.R235S Substitution - Missense 1:149964249-149964249 - TCGA-33-4566-01 COSM675588 c.172G>C p.E58Q Substitution - Missense 1:149971165-149971165 - OSCC-GB_00250111 COSM3711131 c.342C>A p.V114V Substitution - coding silent 1:149967454-149967454 - TCGA-EE-A181-06 COSM3473323 c.1984C>T p.P662S Substitution - Missense 1:149944405-149944405 - 2293782 COSM4608212 c.1496C>A p.A499E Substitution - Missense 1:149944893-149944893 - TCGA-A8-A0A6-01 COSM3801719 c.360T>G p.G120G Substitution - coding silent 1:149967436-149967436 - CSCC-40-T COSM4477001 c.2112C>T p.G704G Substitution - coding silent 1:149944277-149944277 - TCGA-EK-A3GK-01 COSM4854366 c.1255G>C p.E419Q Substitution - Missense 1:149947319-149947319 - H1155 COSM1195578 c.568G>A p.G190R Substitution - Missense 1:149965813-149965813 - TCGA-NH-A5IV-01 COSM2181706 c.964G>A p.G322R Substitution - Missense 1:149950103-149950103 - TCGA-EE-A2MF-06 COSM4893023 c.2066C>T p.S689F Substitution - Missense 1:149944323-149944323 - I2L-P7-Tumor-Organoid COSM2181723 c.366delG p.S123fs*29 Deletion - Frameshift 1:149967430-149967430 - GB02 COSM1744017 c.1800G>A p.R600R Substitution - coding silent 1:149944589-149944589 - SH-0622 COSM5018283 c.2390delC p.P797fs*31 Deletion - Frameshift 1:149943999-149943999 - 1_RESISTANT COSM1719836 c.2222C>T p.P741L Substitution - Missense 1:149944167-149944167 - TCGA-EB-A3XB-01 COSM3473325 c.536C>T p.T179I Substitution - Missense 1:149965845-149965845 - TCGA-DK-A2I4-01 COSM3788633 c.1043C>A p.S348Y Substitution - Missense 1:149949709-149949709 - Pat_50_A COSM5843524 c.347C>T p.S116F Substitution - Missense 1:149967449-149967449 - CSCC-27-T COSM4497069 c.489C>T p.A163A Substitution - coding silent 1:149967307-149967307 - 8014771 COSM3771437 c.842G>A p.G281D Substitution - Missense 1:149959687-149959687 - 398 COSM4428940 c.1664C>T p.S555L Substitution - Missense 1:149944725-149944725 - WA16 COSM241027 c.1370A>G p.E457G Substitution - Missense 1:149945019-149945019 - HRA19 COSM4637624 c.822T>A p.G274G Substitution - coding silent 1:149959707-149959707 - PCSI_0547_Pa_P_526 COSM5032034 c.2469C>A p.Y823* Substitution - Nonsense 1:149943920-149943920 - 18 COSM5744682 c.461_462insGA p.D154fs*18 Insertion - Frameshift 1:149967334-149967335 - C113 COSM4441080 c.808C>T p.R270* Substitution - Nonsense 1:149959721-149959721 - TCGA-HU-A4GT-01 COSM4021921 c.239G>A p.R80Q Substitution - Missense 1:149971098-149971098 - ESO-081 COSM1219007 c.2494C>T p.R832W Substitution - Missense 1:149943895-149943895 - TCGA-B8-5163-01 COSM462896 c.1143T>C p.D381D Substitution - coding silent 1:149949064-149949064 - T55 COSM4710587 c.323C>T p.S108F Substitution - Missense 1:149967473-149967473 - 0024_CRUK_PC_0024_T1_DNA COSM5422514 c.26T>G p.L9R Substitution - Missense 1:149977485-149977485 - TCGA-B5-A0JY-01 COSM895446 c.90G>T p.K30N Substitution - Missense 1:149971247-149971247 - TCGA-A6-6138-01 COSM1333765 c.2114G>T p.G705V Substitution - Missense 1:149944275-149944275 - TCGA-EI-6917-01 COSM3418015 c.281G>A p.R94H Substitution - Missense 1:149967515-149967515 - 2492730 COSM3473320 c.2386C>T p.P796S Substitution - Missense 1:149944003-149944003 - 513 COSM3722924 c.458G>T p.R153I Substitution - Missense 1:149967338-149967338 - B37-Tumor COSM1747715 c.817C>G p.L273V Substitution - Missense 1:149959712-149959712 - S02274 COSM5682324 c.1172T>A p.F391Y Substitution - Missense 1:149949035-149949035 - TCGA-BR-6452-01 COSM4021915 c.1966G>T p.G656* Substitution - Nonsense 1:149944423-149944423 - 113795 COSM96101 c.6C>T p.T2T Substitution - coding silent 1:149977505-149977505 - CSCC-7-T COSM4485976 c.299C>T p.S100F Substitution - Missense 1:149967497-149967497 - TCGA-BS-A0UV-01 COSM895439 c.1638G>A p.E546E Substitution - coding silent 1:149944751-149944751 - TCGA-GN-A269-01 COSM3473326 c.330C>T p.A110A Substitution - coding silent 1:149967466-149967466 - 107050 COSM94895 c.2497G>A p.E833K Substitution - Missense 1:149943892-149943892 - 43T COSM110148 c.235C>T p.P79S Substitution - Missense 1:149971102-149971102 - Pat_44_A COSM5843520 c.2303C>T p.P768L Substitution - Missense 1:149944086-149944086 - 2492703 COSM5716653 c.232C>T p.P78S Substitution - Missense 1:149971105-149971105 - TCGA-CC-5258-01 COSM4933447 c.2168G>T p.G723V Substitution - Missense 1:149944221-149944221 - 587306 COSM1219007 c.2494C>T p.R832W Substitution - Missense 1:149943895-149943895 - STC252 COSM5052522 c.894C>T p.H298H Substitution - coding silent 1:149950173-149950173 - U251 COSM1683784 c.1646_1648delAGA p.K553delK Deletion - In frame 1:149944741-149944743 - 16461 COSM5613750 c.1190A>T p.K397M Substitution - Missense 1:149949017-149949017 - TCGA-F1-A448-01 COSM4021919 c.822T>C p.G274G Substitution - coding silent 1:149959707-149959707 - TCGA-BR-4255-01 COSM4021918 c.1004A>G p.Y335C Substitution - Missense 1:149949748-149949748 - SC_9047 COSM5560738 c.432T>C p.N144N Substitution - coding silent 1:149967364-149967364 - HOP-92 COSM1683784 c.1646_1648delAGA p.K553delK Deletion - In frame 1:149944741-149944743 - ESCC_110 COSM5639177 c.939G>T p.V313V Substitution - coding silent 1:149950128-149950128 - TCGA-DD-A4NV-01 COSM4916435 c.2529C>T p.F843F Substitution - coding silent 1:149943860-149943860 - CSCC-62-T COSM4479220 c.2304C>T p.P768P Substitution - coding silent 1:149944085-149944085 - pfg043T COSM4762510 c.1370A>T p.E457V Substitution - Missense 1:149945019-149945019 - T3152 COSM4477001 c.2112C>T p.G704G Substitution - coding silent 1:149944277-149944277 - B37 COSM1747715 c.817C>G p.L273V Substitution - Missense 1:149959712-149959712 - OSCC-GB_01340111 COSM5954805 c.1834G>C p.V612L Substitution - Missense 1:149944555-149944555 - LUAD-S01315 COSM344812 c.585C>G p.L195L Substitution - coding silent 1:149965796-149965796 - YUKAT COSM4710587 c.323C>T p.S108F Substitution - Missense 1:149967473-149967473 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.98322 1q21.2 611748

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer ACCC - IntronicDeletion . c.1-20000_1-19997delGGTG 1 149969443 CLL A G IntronicSNV . c.1-22814T>C 1 149972259 CLL A G Synonymous p.D381D c.1143T>C 1 149920966 RCCC A G Synonymous p.Y384Y c.1152T>C 1 149920957 RCCC C A Missense p.A789S c.2365G>T 1 149915923 LUAD C A Missense p.G568W c.1702G>T 1 149916586 NSCLC C A Missense p.G659V c.1976G>T 1 149916312 LUAD C A Missense p.G98V c.293G>T 1 149939428 BRCA C A Missense p.R492L c.1475G>T 1 149916813 LUAD C A Missense p.R832L c.2495G>T 1 149915793 LUAD C A Missense p.S57I c.170G>T 1 149943095 BRCA C A Missense p.W204C c.612G>T 1 149936267 LUAD C A Missense p.W788C c.2364G>T 1 149915924 LUAD C A Nonsense p.E292* c.874G>T 1 149922096 HNSC C A Nonsense p.G584* c.1750G>T 1 149916538 LUAD C G Missense p.D456H c.1366G>C 1 149916922 LUSC C G Synonymous p.L261L c.783G>C 1 149931665 HNSC C - IntronicDeletion . c.732+197delG 1 149935950 RCCC C T IntronicSNV . c.732+1135G>A 1 149935012 DLBCL C T Missense p.A353T c.1057G>A 1 149921598 RCCC C T Missense p.A499T c.1495G>A 1 149916793 STAD C T Missense p.E251K c.751G>A 1 149931697 BRCA C T Missense p.R270Q c.809G>A 1 149931639 LUSC C T Missense p.R45H c.134G>A 1 149943131 UCEC C T Missense p.R700Q c.2099G>A 1 149916189 LUSC C T Missense p.R738Q c.2213G>A 1 149916075 BLCA C T Missense p.S175N c.524G>A 1 149937782 BRCA C T Missense p.S597N c.1790G>A 1 149916498 HNSC G A IntronicSNV . c.732+221C>T 1 149935926 HC G A Missense p.A664V c.1991C>T 1 149916297 CM G A Missense p.H298Y c.892C>T 1 149922078 BRCA G A Missense p.H304Y c.910C>T 1 149922060 COREAD G A Missense p.P185S c.553C>T 1 149937753 CM G A Missense p.P662S c.1984C>T 1 149916304 CM G A Missense p.P731L c.2192C>T 1 149916096 CM G A Missense p.R484W c.1450C>T 1 149916838 UCEC G A Missense p.R94C c.280C>T 1 149939441 STAD G A Missense p.S438F c.1313C>T 1 149919162 LUAD G A Missense p.S501F c.1502C>T 1 149916786 CM G A Missense p.S689F c.2066C>T 1 149916222 CM G A Nonsense p.Q84* c.250C>T 1 149943015 COREAD G A Synonymous p.A110A c.330C>T 1 149939391 CM G A Synonymous p.A37A c.111C>T 1 149943154 LUAD G A Synonymous p.I82I c.246C>T 1 149943019 THCA G A Synonymous p.I89I c.267C>T 1 149942998 CM G A Synonymous p.P388P c.1164C>T 1 149920945 CM G C Missense p.L350V c.1048C>G 1 149921607 SCLC G C Missense p.Q356E c.1066C>G 1 149921589 BLCA G C Nonsense p.S453* c.1358C>G 1 149916930 UCEC GG AA Missense p.P127F c.379_380delinsTT 1 149939341 CM G T Missense p.A499E c.1496C>A 1 149916792 CM G T Missense p.P54Q c.161C>A 1 149943104 LUAD G T Missense p.S348Y c.1043C>A 1 149921612 BLCA G T Synonymous p.R270R c.808C>A 1 149931640 LUAD T A Missense p.I698F c.2092A>T 1 149916196 BRCA T A Missense p.K397M c.1190A>T 1 149920919 NSCLC T A Missense p.T800S c.2398A>T 1 149915890 HNSC T C Missense p.E565G c.1694A>G 1 149916594 ESCA T C Missense p.R232G c.694A>G 1 149936185 COREAD T C Missense p.Y335C c.1004A>G 1 149921651 STAD T C Synonymous p.A219A c.657A>G 1 149936222 LUAD T G Missense p.K651T c.1952A>C 1 149916336 UCEC