PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RCC1 KMT2B 21900206 biogrid,mint,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CRK KMT2B 17474147 i2d,intact exp G G G G G G G GP GP G GP GP G G G G G G GP G GP G G G G G GP G G ANXA1 KMT2B 21900206 biogrid,mint,intact exp G G G G GP GP G G GP G GP G GP GP G G GP G G G GP G G G G GP G G G ABL1 KMT2B 17474147 i2d,mint,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G BCL6 KMT2B 16147992 biogrid,intact,bci exp G G G G GP G G G G G G G G GP G G G G G G GP G G G G GP G G G PAXIP1 KMT2B 17500065 biogrid exp G GP G G GP GP G GP GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G WDR77 KMT2B 23995757 dip exp G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ZNF512B KMT2B 15231748 biogrid,i2d,mint,intact exp G GP G G G GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G NREP KMT2B 21900206 biogrid,mint,intact exp G GP G G G GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G FOXK2 KMT2B 25609649 intact exp G GP G G GP GP G GP GP G GP GP G G G G GP G GP G GP G G G G G GP GP G SMN1, SMN2 KMT2B 21900206 biogrid,mint,intact exp P P P P P P P P P P P P P P DPY30 KMT2B 23995757 dip exp G GP G G GP GP G G GP G GP GP GP G G G GP G GP G GP G G G G GP GP GP G TSC22D1 KMT2B 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 KMT2B 15231748 hprd,biogrid,i2d,mint,intact exp G GP G G G GP G G G G G G GP GP G G GP G GP G GP G G G G G G G G ATP1B1 KMT2B 21900206 biogrid,mint,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G HNRNPF KMT2B 23995757 dip exp G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PSIP1 KMT2B 23995757 dip exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G TK1 KMT2B 21900206 biogrid,mint,intact exp G GP G GP P G G GP G GP GP GP G P G G G GP G G G GP G THOC2 KMT2B 26496610 biogrid,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ANXA7 KMT2B 21900206 biogrid,mint,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PSTPIP1 KMT2B 17353931 intact exp G G GP G GP G GP GP G G G G GP G G RAP1B KMT2B 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HIST2H3A, HIST2H3C, HIST2H3D KMT2B 22266653 biogrid exp P P P P P P P P P P P P P P P HCFC1 KMT2B 23995757 dip exp G GP G G GP GP G GP G G GP GP GP G G G GP G G G G G G G G G GP GP G NCK1 KMT2B 17474147 i2d,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G FYN KMT2B 17474147 i2d,mint,intact exp G GP G G GP GP G G GP G GP GP G GP G G GP G G G G G G G G GP G G G MEN1 KMT2B 22327296 dip exp G GP G G GP GP G G GP G GP GP GP GP G G GP G G G GP G G G G G GP GP G WDR82 KMT2B 20516061 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRB7 KMT2B 21900206 biogrid,mint,intact exp G GP G G GP GP GP GP G GP GP GP GP G G GP G GP G GP G G G G P GP GP G PIK3R3 KMT2B 25814554 biogrid,intact exp G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G QRICH2 KMT2B 23995757 dip exp P P P P P P P P P GP P P GP PRPF40A KMT2B 9171351,10744724 hprd,bci exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G GRB2 KMT2B 17474147 i2d,intact exp G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G KHSRP KMT2B 23995757 dip exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PAGR1 KMT2B 17500065 biogrid exp G GP G G GP GP G GP GP G GP GP P G G G GP G GP G GP G G G G GP GP GP G CDKN1A KMT2B 21900206 biogrid,mint,intact exp G GP G G GP G G G GP G G G GP G G G G G G G GP G G G G G G GP G SMARCB1 KMT2B 19221051 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PIN1 KMT2B 21900206 biogrid,mint,intact exp G GP G G GP GP G G GP G G G G GP G G GP G P G P G G G G G GP GP G RPP14 KMT2B 21900206 biogrid,mint,intact exp G GP G G G GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G SEPT8 KMT2B 21900206 biogrid,mint,intact exp G P G P GP G GP G P P P P G GP P GP G G P GP P NCOA6 KMT2B 17021013,19047629 biogrid,dip exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ATXN1 KMT2B 16713569 hprd,biogrid,mint,intact exp G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G MAP1B KMT2B 23995757 dip exp G GP G G G GP G G GP G GP G G G G G GP G GP G GP G G G G G G GP G HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J KMT2B 23870121 biogrid exp, ortho GP G GP P GP P P P P P P P P G G G GP P P ASH2L KMT2B 20305087,17500065,23995757, 25402006 biogrid,dip exp, pred G GP G G GP GP G GP GP G GP G G G G G GP G GP G GP G G G G G GP GP G RBBP5 KMT2B 17500065,23995757,21502505, 25402006 biogrid,dip exp, pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP WDR5 KMT2B 20305087,22665483,23995757,26186194,24788516,22266653, 25402006 biogrid,intact,dip exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KMT2A KMT2B 18840606, 25402006, 23023127 intact exp, pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G YWHAE KMT2B ortho G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G NANOG KMT2B ortho P P G P G P G GP SHROOM2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX6 KMT2B 16082366 pred G GP G G G GP G GP GP G GP GP GP G G G GP G GP G GP G G G G G GP GP G SUV39H2 KMT2B 25402006, 23023127, 16082366 pred G G G G G G G G G G G G GP GP SEPN1 KMT2B 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G WASL KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G SLC23A1 KMT2B 25402006 pred G G P P GP G P G P G G G P CELSR3 KMT2B 25402006 pred G GP G G G GP G G GP G GP GP GP G G GP G GP G GP G G G G GP GP GP G CAST KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G KAT6B KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ASB16 KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CXXC1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G EP300 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX4 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G NCKIPSD KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G MORF4L1 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G YLPM1 KMT2B 25402006 pred G GP G G G GP G GP GP G GP GP GP G G G GP G G G GP G G G G G GP GP G NKX2-1 KMT2B 25402006 pred G GP G G CHD1 KMT2B 16082366 pred G G G G G GP G GP GP G GP GP G GP G G GP G GP G GP G G G G G GP GP G MLLT1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G SF3A2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G SETD8 KMT2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 KMT2B 25402006 pred P P P P P P P P P P P P P P P CYP4F2 KMT2B 25402006 pred P G GP P P GP GP P G G G P P SF1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CREBBP KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CHD6 KMT2B 23023127, 16082366 pred G G G G G GP G GP GP G G G GP G G G GP G G G G G G G G G G G G EPHB1 KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G SLC24A1 KMT2B 25402006 pred G GP P GP G G G G G G G G GP G TP53BP1 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G HTT KMT2B 25402006 pred G GP G G GP GP G G GP G P GP P GP G G GP G P G GP G G G G GP GP GP CHD8 KMT2B 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FMNL1 KMT2B 25402006 pred G G G GP G G GP GP G G G G G G G GP G ARNT2 KMT2B 16082366 pred P G GP G GP G G GP G G GP G G G G G G G G GP G SP1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ABCG5 KMT2B 25402006 pred P P P P G P G P P G P P ID4 KMT2B 25402006 pred G GP G G G GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ARID4A KMT2B 16082366 pred G P G GP G P G P GP G G GP G P G P G G G G G G P G RAG1 KMT2B 25402006 pred GAD1 KMT2B 25402006 pred G GP G G GP G DNMT3B KMT2B 25402006 pred G P G G GP GP G GP P GP GP GP P G G GP G GP G GP G G G GP GP GP TDRD1 KMT2B 23023127 pred P P P P P P P P P P P P P P GP SYNJ2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP P GP G G GP G GP G GP G G G G GP GP P G SNX17 KMT2B 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX8 KMT2B 16082366 pred P P P P P P P P P P P P P P DLX4 KMT2B 25402006 pred G GP G G G GP G G GP G GP G GP P G GP G GP G GP G G G GP GP G MECP2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G KMT2B DLGAP4 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G CHD3 KMT2B 25402006 pred G GP G G G GP G G GP G GP G GP GP G G GP G GP G GP G G G G G GP GP G ARID1B KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G BAZ1A KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G POU5F1 KMT2B 21836163 pred P P P P P P P P P P P P P P P TNK2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ZCCHC8 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G ISG20L2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G U2AF2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G KMT2B RIMS2 25402006 pred GP G G GP GP G P P G P P P GP GP GP G GP G P P GP G BRPF3 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G DUSP15 KMT2B 25402006 pred G G G G G GP G G GP G GP G GP G G G GP G GP G G G G G G GP GP G NSD1 KMT2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KMT2B ASF1A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CBX2 KMT2B 16082366 pred P GP P P G G P P GP G G BAZ1B KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PHACTR2 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G FMNL3 KMT2B 25402006 pred G GP G G GP GP G P GP G P P GP GP G G GP G P G GP GP GP GP G SMARCC2 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX3 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G C6 KMT2B 25402006 pred G G G G P G G G GP GP GP G G G GP G G G G G G G G G G cDNA FLJ76680, highly similar to Homo sapiens chromodomain protein, Y-linked, 1 (CDY1), transcript variant 2, mRNA KMT2B 16082366 pred HNRNPUL1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G SCARF2 KMT2B 25402006 pred P P P P P P GP GP G G P G P GP GP P P G KMT2B CDYL 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G MAP4 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G BAHD1 KMT2B 23023127 pred G G G G G G G G G G GP G G G G G G G G G G G G G G G G G G SEC14L2 KMT2B 16082366 pred P G P GP P P G P GP P P G GP GP P G P P P G HNRNPR KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G BAZ2A KMT2B 25402006, 23023127 pred G GP G G G GP G G GP G GP G GP G G G GP G GP G GP G G G G G GP GP G PRDM7 KMT2B 23023127 pred P P P KMT2B SNX12 25402006 pred G GP G G G GP G GP GP G GP GP GP G G G GP G GP G GP G G G G G GP GP G RLIM KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX5 KMT2B 16082366 pred G GP G G GP GP G G GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G TULP1 KMT2B 25402006 pred G G G G G G PHF21A KMT2B 23023127 pred G GP G G GP GP G GP GP G GP G GP G G G GP G P G GP G G G G G G GP G GNS KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CBX7 KMT2B 16082366 pred G GP G G G GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PNMA2 KMT2B 25402006 pred G GP G G G GP G GP GP G GP P GP G G G GP G GP G G G GP GP G TPSAB1 KMT2B 25402006 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G G G G SOCS7 KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MINK1 KMT2B 25402006 pred G G G G G GP G G GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G PIK3C2B KMT2B 25402006 pred G G G G G G G G GP G GP GP GP G G G G G GP G GP G G G G G GP G G CTCF KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G GSTZ1 KMT2B 25402006 pred G GP P P P P G GP GP P GP G G P GP P G G G G P P GP G ELK3 KMT2B 25402006 pred G G G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G G GP G DLGAP3 KMT2B 25402006 pred G GP P P G P P GP P G SMARCD1 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G PHF1 KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G KMT2E KMT2B 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G G G G GP G WHSC1L1 KMT2B 23023127 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G LRRC3 KMT2B 25402006 pred P P P P P P P P P P P P P P P DIAPH1 KMT2B 25402006 pred G GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G VPS13A KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G SEMA7A KMT2B 25402006 pred GP G G G GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G G GP GP G CDK12 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G KMT2C KMT2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SHANK3 KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G BPTF KMT2B 23023127 pred G GP G G G GP G G GP G GP GP GP G G G GP G G G GP G G G G G GP GP G PRX KMT2B 25402006 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G G G G G G KMT2B SNX8 25402006 pred G GP G P GP G P P G GP P P GP G G GP P G GP G GP P GP G SMARCC1 KMT2B 16082366 pred G G G G GP GP G G GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G FCGR2C KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SPEN KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G MEPE KMT2B 25402006 pred P P P P P P P P P P P P P P SUV39H1 KMT2B 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CBX1 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G FOXH1 KMT2B 25402006 pred G G G G G G G G G G G G G G G DLGAP2 KMT2B 25402006 pred GP G P GP G GP GP G GP GP P P GP G GP G P G P GP G NCKAP5 KMT2B 25402006 pred P P P P P GP P P P P P P CDYL2 KMT2B 16082366 pred G GP G G GP GP G GP GP G GP G GP GP G G GP G GP G GP G G G G GP GP GP G GLTSCR1 KMT2B 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G G GP G GP G GP G G G G GP GP GP G CHD2 KMT2B 16082366 pred P P P P P P P P P P P P P P P PDIA2 KMT2B 25402006 pred G G G G G G G G G GP G G G GP

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UMN6 A0A024R5Z3 - 15231748 - X 2 Q9UMN6 Q96KM6 - 15231748 - X 2 Q9UMN6 P61964 unspecified method 22665483 direct interaction X 2 Q9UMN6 P61964 x-ray crystallography 22266653 association X 2 Q9UMN6 P61964 unspecified method 22266653 direct interaction X 2 Q9UMN6 Q96FF1 two hybrid 16713569 direct interaction X 2 Q9UMN6 Q96KM6 two hybrid 15231748 direct interaction X 2 Q9UMN6 P68431 enzymatic study 23870121 direct interaction X 2 Q9UMN6 Q6ZW49 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 Q6ZW49 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 Q6ZW49 biochemical 17500065 association X 2 Q9UMN6 Q6ZW49 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 B4DPT1 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 P41182 affinity chromatography technology 16147992 physical association X 2 Q9UMN6 P61224-4 two hybrid 21900206 direct interaction X 2 Q9UMN6 two hybrid 21900206 direct interaction X 2 Q9UMN6 P04183 two hybrid 21900206 direct interaction X 2 Q9UMN6 P04083 two hybrid 21900206 direct interaction X 2 Q9UMN6 Q16637 two hybrid 21900206 direct interaction X 2 Q9UMN6 A0A024RDV8 two hybrid 21900206 direct interaction X 2 Q9UMN6 affinity chromatography technology 21502505 physical association X 2 Q9UMN6 B4DPT1 affinity chromatography technology 20305087 physical association X 2 Q9UMN6 P61964 affinity chromatography technology 20305087 physical association X 2 A0A024R333 Q9UMN6 affinity chromatography technology 20516061 physical association X 2 A0A024R333 Q9UMN6 affinity chromatography technology 20516061 physical association X 2 Q9UMN6 Q71DI3 enzymatic study 22266653 direct interaction X 2 Q9UMN6 two hybrid 15231748 direct interaction X 2 Q9UMN6 P0CG48 affinity chromatography technology 23000965 physical association X 2 Q9UMN6 Q9H836 pull down 19221051 direct interaction X 2 Q9UMN6 affinity chromatography technology 19047629 physical association X 2 Q9UMN6 affinity chromatography technology 17021013 physical association X 2 Q9UMN6 Q9BTK6 affinity chromatography technology 17500065 physical association X 2 Q9UMN6 Q14451-3 two hybrid 21900206 direct interaction X 2 Q9UMN6 A3KLL5 two hybrid 21900206 direct interaction X 2 Q9UMN6 O95059 two hybrid 21900206 direct interaction X 2 Q9UMN6 two hybrid 21900206 direct interaction X 2 Q9UMN6 A0A024RCX5 two hybrid 21900206 direct interaction X 2 Q9UMN6 two hybrid 21900206 direct interaction X 2 Q9UMN6 Q13526 two hybrid 21900206 direct interaction X 2 Q9UMN6 P20073-2 two hybrid 21900206 direct interaction X 2 Q9UMN6 P0CG48 affinity chromatography technology 21890473 physical association X 2 Q9UMN6 molecular sieving 17500065 association C 10 Q9UMN6 anti tag coimmunoprecipitation 17500065 association C 10 Q9UMN6 cosedimentation through density gradient 14992727 association C 7 Q9UMN6 anti bait coimmunoprecipitation 14992727 association C 7 Q9UMN6 anti tag coimmunoprecipitation 23995757 - C 13 Q9UMN6 anti bait coimmunoprecipitation 23995757 - C 4 Q9UMN6 anti bait coimmunoprecipitation 23995757 - C 4 Q9UMN6 anti bait coimmunoprecipitation 19047629 - C 11 Q14686 Q9UMN6 anti bait coimmunoprecipitation 19047629 physical association X 2 Q14686 Q9UMN6 anti bait coimmunoprecipitation 19433796 physical association X 2 A0A024R0H7 Q9UMN6 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 O00255 anti bait coimmunoprecipitation 23995757 direct interaction X 2 Q9UMN6 O00255 anti tag coimmunoprecipitation 23995757 direct interaction X 2 Q9UMN6 O00255 isothermal titration calorimetry 22327296 direct interaction X 2 Q9UMN6 P61964 anti bait coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 P61964 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 A0A024R9B5 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 P46821 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 O75475 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 P51610 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 A0A024R7T3 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 anti tag coimmunoprecipitation 23995757 - C 17 Q9UMN6 molecular sieving 23995757 physical association C 7 Q9UMN6 anti tag coimmunoprecipitation 23995757 - C 5 Q9UMN6 molecular sieving 19433796 physical association C 3 Q9UMN6 ion exchange chromatography 19433796 physical association C 3 Q9UMN6 anti bait coimmunoprecipitation 19433796 - C 11 Q9UMN6 anti bait coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q9C005 anti bait coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q9C005 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q9C005 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q9C005 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q92945 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 Q9H0J4 anti tag coimmunoprecipitation 23995757 physical association X 2 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 in vivo 17500065 - C 9 Q9UMN6 P54253 two hybrid 16713569 - X 2 Q9UMN6 in vitro 10744724,9171351 - X 2 Q9UMN6 P54253 two hybrid 16713569 - X 2 Q9UMN6 in vitro 10744724,9171351 - X 2 Q9UMN6 P84022-4 two hybrid 15231748 - X 2 Q9UMN6 P84022-4 two hybrid 15231748 - X 2 Q9UMN6 pull down 18840606 direct interaction C 3 Q9UMN6 anti bait coimmunoprecipitation 16147992 association C 64 Q9UMN6 Q96KM6 two hybrid 15231748 physical association X 2 Q9UMN6 A0A024R5Z3 two hybrid 15231748 physical association X 2 Q9UMN6 P54253 two hybrid 16713569 physical association X 2 Q9UMN6 P16333 peptide array 17474147 physical association X 2 Q9UMN6 P16333 peptide array 17474147 physical association X 2 Q9UMN6 A0A024R8E2 peptide array 17474147 physical association X 2 Q9UMN6 P06241 peptide array 17474147 physical association X 2 Q9UMN6 Q7CGD4 two hybrid pooling approach 20711500 physical association X 2 Q9UMN6 Q14451 two hybrid 21900206 physical association X 2 Q9UMN6 P04083 two hybrid 21900206 physical association X 2 Q9UMN6 Q16637 two hybrid 21900206 physical association X 2 Q9UMN6 P04183 two hybrid 21900206 physical association X 2 Q9UMN6 P61964 isothermal titration calorimetry 24788516 direct interaction X 2 P18754 Q9UMN6 two hybrid 21900206 physical association X 2 Q9UMN6 isothermal titration calorimetry 24788516 physical association C 3 Q9UMN6 O43586 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9UMN6 B0LPF3 peptide array 17474147 physical association X 2 Q9UMN6 L7RT18 peptide array 17474147 physical association X 2 Q9UMN6 Q8CLT1 two hybrid pooling approach 20711500 physical association X 2 Q9UMN6 P20073 two hybrid 21900206 physical association X 2 Q9UMN6 A3KLL5 two hybrid 21900206 physical association X 2 Q9UMN6 Q13526 two hybrid 21900206 physical association X 2 Q9UMN6 A0A024RB87 two hybrid 21900206 physical association X 2 Q9UMN6 O95059 two hybrid 21900206 physical association X 2 Q9UMN6 Q92599 two hybrid 21900206 physical association X 2 Q9UMN6 Q16612 two hybrid 21900206 physical association X 2 Q9UMN6 A0A024RCX5 two hybrid 21900206 physical association X 2 Q9UMN6 Q15714 two hybrid 21900206 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UMN6 Q8NI27 KMT2B THOC2 0.126 26496610 Q9UMN6 Q6UXN9 KMT2B WDR82 0.126 20516061 Q9UMN6 Q7CGD4 KMT2B Q7CGD4 0.126 20711500 Q9UMN6 P04183 KMT2B TK1 0.332 21900206 Q9UMN6 Q92599 KMT2B SEPT8 0.332 21900206 Q9UMN6 Q92569 KMT2B PIK3R3 0.286 25814554 Q9UMN6 Q96KM6 KMT2B ZNF512B 0.332 15231748 Q9UMN6 Q14451 KMT2B GRB7 0.332 21900206 Q9UMN6 Q13526 KMT2B PIN1 0.332 21900206 Q9UMN6 P18754 KMT2B RCC1 0.332 21900206 Q9UMN6 P84022 KMT2B SMAD3 0.332 15231748 Q9UMN6 Q6P5D4 KMT2B CEP135 0.236 26496610 Q9UMN6 Q60967 KMT2B PAPSS1 0.236 26496610 Q9UMN6 P41182 KMT2B BCL6 0.236 16147992 Q9UMN6 P61224 KMT2B RAP1B 0.332 21900206 Q9UMN6 Q9BTK6 KMT2B PAGR1 0.126 17500065 Q9UMN6 P38936 KMT2B CDKN1A 0.183 21900206 Q9UMN6 O43586 KMT2B PSTPIP1 0.126 17353931 Q9UMN6 O95059 KMT2B RPP14 0.332 21900206 Q9UMN6 P00519 KMT2B ABL1 0.236 17474147 Q9UMN6 P04083 KMT2B ANXA1 0.332 21900206 Q9UMN6 P05026 KMT2B ATP1B1 0.332 21900206 Q9UMN6 P06241 KMT2B FYN 0.126 17474147 Q9UMN6 P16333 KMT2B NCK1 0.236 17474147 Q9UMN6 P20073 KMT2B ANXA7 0.183 21900206 Q9UMN6 P54253 KMT2B ATXN1 0.332 16713569 Q9UMN6 P61964 KMT2B WDR5 0.88 27705803,20305087,24788516,22665483,22266653,26186194 Q9UMN6 P68431 KMT2B HIST1H3J 0.183 23870121 Q9UMN6 Q14686 KMT2B NCOA6 0.507 19047629,17021013 Q9UMN6 Q15291 KMT2B RBBP5 0.309 17500065,21502505 Q9UMN6 Q15714 KMT2B TSC22D1 0.183 21900206 Q9UMN6 Q16637 KMT2B SMN2 0.332 21900206 Q9UMN6 Q6ZW49 KMT2B PAXIP1 0.332 17500065 Q9UMN6 Q71DI3 KMT2B HIST2H3D 0.309 22266653 Q9UMN6 Q8CLT1 KMT2B Q8CLT1 0.126 20711500 Q9UMN6 Q9UBL3 KMT2B ASH2L 0.472 17500065,26886794,20305087 Q9UMN6 P46108 KMT2B CRK 0.126 17474147 Q9UMN6 Q12824 KMT2B SMARCB1 0.309 19221051 Q9UMN6 P62993 KMT2B GRB2 0.126 17474147 Q9UMN6 Q01167 KMT2B FOXK2 0.126 25609649 Q9UMN6 P68400 KMT2B CSNK2A1 0.126 27705803 Q9UMN6 Q16612 KMT2B NREP 0.183 21900206 Q9UMN6 Q3U647 KMT2B PAPSS1 0.126

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MEN1 KMT2B MI:0362 inference MI:0461 interaction database UTY KMT2B MI:0362 inference MI:0461 interaction database KDM6A KMT2B MI:0362 inference MI:0461 interaction database PAPSS1 KMT2B MI:0362 inference MI:0461 interaction database PSTPIP1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database AKAP8 KMT2B MI:0362 inference MI:0461 interaction database SMARCA5 KMT2B MI:0362 inference MI:0461 interaction database PSIP1 KMT2B MI:0362 inference MI:0461 interaction database MTA2 KMT2B MI:0362 inference MI:0461 interaction database RPP14 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database ABL1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database ANXA1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database TK1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database ATP1B1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database FYN KMT2B MI:0045 experimental interaction detection MI:0461 interaction database UBC KMT2B MI:0045 experimental interaction detection MI:0461 interaction database NCK1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database RCC1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database ANXA7 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database LMO2 KMT2B MI:0362 inference MI:0461 interaction database SMARCA1 KMT2B MI:0362 inference MI:0461 interaction database CDKN1A KMT2B MI:0045 experimental interaction detection MI:0461 interaction database BCL6 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database CRK KMT2B MI:0045 experimental interaction detection MI:0461 interaction database MAP1B KMT2B MI:0362 inference MI:0461 interaction database HCFC1 KMT2B MI:0362 inference MI:0461 interaction database HNRNPF KMT2B MI:0362 inference MI:0461 interaction database ATXN1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database ACTB KMT2B MI:0362 inference MI:0461 interaction database RAP1B KMT2B MI:0045 experimental interaction detection MI:0461 interaction database WDR5 KMT2B MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database GRB2 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A KMT2B MI:0045 experimental interaction detection MI:0461 interaction database SMAD3 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database H3F3A KMT2B MI:0362 inference MI:0461 interaction database FOXK2 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database KMT2A KMT2B MI:0045 experimental interaction detection MI:0461 interaction database RBBP4 KMT2B MI:0362 inference MI:0461 interaction database SMARCB1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database BPTF KMT2B MI:0362 inference MI:0461 interaction database TP53BP1 KMT2B MI:0362 inference MI:0461 interaction database PIN1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database GRB7 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database NCOA6 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database RBBP5 KMT2B MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TSC22D1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database NREP KMT2B MI:0045 experimental interaction detection MI:0461 interaction database SMN1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database CEP135 KMT2B MI:0362 inference MI:0461 interaction database WDR82 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database PAXIP1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database HIST2H3A KMT2B MI:0045 experimental interaction detection MI:0461 interaction database KANSL1 KMT2B MI:0362 inference MI:0461 interaction database BAP18 KMT2B MI:0362 inference MI:0461 interaction database KMT2C KMT2B MI:0362 inference MI:0461 interaction database THOC2 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database PIK3R3 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database SEPT8 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database KHSRP KMT2B MI:0362 inference MI:0461 interaction database ZNF462 KMT2B MI:0362 inference MI:0461 interaction database ZNF512B KMT2B MI:0045 experimental interaction detection MI:0461 interaction database WDR77 KMT2B MI:0362 inference MI:0461 interaction database PAGR1 KMT2B MI:0045 experimental interaction detection MI:0461 interaction database DPY30 KMT2B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database QRICH2 KMT2B MI:0362 inference MI:0461 interaction database KANSL2 KMT2B MI:0362 inference MI:0461 interaction database NANOG KMT2B MI:0362 inference MI:0461 interaction database CXXC1 KMT2B MI:0362 inference MI:0461 interaction database ASH2L KMT2B MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HMGXB4 KMT2B MI:0362 inference MI:0461 interaction database KMT2B SATB2 MI:0362 inference MI:0461 interaction database