Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 16 14761544 14761544 + Missense_Mutation SNP C C A TCGA-OR-A5LO-01A-11D-A29I-10 TCGA-OR-A5LO-10A-01D-A29L-10 g.chr16:14761544C>A c.1213C>A c.(1213-1215)Ctt>Att p.L405I BLCA 16 14738279 14738279 + Nonsense_Mutation SNP C C T TCGA-FD-A3SN-01A-12D-A22Z-08 TCGA-FD-A3SN-10A-01D-A22Z-08 g.chr16:14738279C>T c.76C>T c.(76-78)Cag>Tag p.Q26* BLCA 16 14738367 14738367 + Missense_Mutation SNP G G A TCGA-DK-AA6P-01A-11D-A391-08 TCGA-DK-AA6P-10A-01D-A394-08 g.chr16:14738367G>A c.164G>A c.(163-165)cGt>cAt p.R55H BLCA 16 14738401 14738401 + Missense_Mutation SNP G G C TCGA-ZF-AA4V-01A-11D-A38G-08 TCGA-ZF-AA4V-10A-01D-A38J-08 g.chr16:14738401G>C c.198G>C c.(196-198)aaG>aaC p.K66N BLCA 16 14738417 14738417 + Missense_Mutation SNP G G C TCGA-MV-A51V-01A-11D-A26M-08 TCGA-MV-A51V-10A-01D-A26K-08 g.chr16:14738417G>C c.214G>C c.(214-216)Gaa>Caa p.E72Q BLCA 16 14742410 14742410 + Silent SNP A A T TCGA-5N-A9KI-01A-31D-A42E-08 TCGA-5N-A9KI-10A-01D-A42H-08 g.chr16:14742410A>T c.429A>T c.(427-429)ggA>ggT p.G143G BLCA 16 14748942 14748942 + Missense_Mutation SNP G G A TCGA-CF-A3MG-01A-11D-A20D-08 TCGA-CF-A3MG-10A-01D-A20D-08 g.chr16:14748942G>A c.658G>A c.(658-660)Gag>Aag p.E220K BLCA 16 14749055 14749055 + Silent SNP C C T TCGA-CF-A27C-01A-11D-A16O-08 TCGA-CF-A27C-10A-01D-A16O-08 g.chr16:14749055C>T c.771C>T c.(769-771)ctC>ctT p.L257L BLCA 16 14761496 14761496 + Missense_Mutation SNP G G A TCGA-GU-A42Q-01A-11D-A23U-08 TCGA-GU-A42Q-10A-01D-A23U-08 g.chr16:14761496G>A c.1165G>A c.(1165-1167)Gtg>Atg p.V389M BLCA 16 14761587 14761587 + Frame_Shift_Del DEL G G - TCGA-DK-AA6S-01A-21D-A391-08 TCGA-DK-AA6S-10A-01D-A394-08 g.chr16:14761587delG c.1256delG c.(1255-1257)tgcfs p.C419fs BRCA 16 14738316 14738316 + Missense_Mutation SNP A A C TCGA-E2-A15M-01A-11D-A12B-09 TCGA-E2-A15M-11A-22D-A12B-09 g.chr16:14738316A>C c.113A>C c.(112-114)tAc>tCc p.Y38S BRCA 16 14748927 14748927 + Missense_Mutation SNP C C G TCGA-D8-A1JP-01A-11D-A13L-09 TCGA-D8-A1JP-10A-01D-A13O-09 g.chr16:14748927C>G c.643C>G c.(643-645)Ctt>Gtt p.L215V BRCA 16 14761577 14761577 + Nonsense_Mutation SNP C C T TCGA-BH-A0B6-01A-11D-A19Y-09 TCGA-BH-A0B6-10A-01D-A19Y-09 g.chr16:14761577C>T c.1246C>T c.(1246-1248)Cag>Tag p.Q416* CESC 16 14749014 14749014 + Missense_Mutation SNP G G C TCGA-C5-A1M8-01A-21D-A13W-08 TCGA-C5-A1M8-10A-01D-A13W-08 g.chr16:14749014G>C c.730G>C c.(730-732)Gaa>Caa p.E244Q CESC 16 14749053 14749053 + Missense_Mutation SNP C C A TCGA-EK-A3GK-01A-11D-A20U-09 TCGA-EK-A3GK-10A-01D-A20U-09 g.chr16:14749053C>A c.769C>A c.(769-771)Ctc>Atc p.L257I CESC 16 14761513 14761513 + Missense_Mutation SNP G G C TCGA-JW-A5VL-01A-11D-A28B-09 TCGA-JW-A5VL-10A-01D-A28E-09 g.chr16:14761513G>C c.1182G>C c.(1180-1182)tgG>tgC p.W394C COAD 16 14738383 14738383 + Silent SNP A A G TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr16:14738383A>G c.180A>G c.(178-180)ttA>ttG p.L60L COAD 16 14742400 14742400 + Missense_Mutation SNP T T G TCGA-AZ-4681-01A-01D-1408-10 TCGA-AZ-4681-10A-01D-1408-10 g.chr16:14742400T>G c.419T>G c.(418-420)aTg>aGg p.M140R COAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-AD-6963-01A-11D-1924-10 TCGA-AD-6963-10A-01D-1924-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-CA-6718-01A-11D-1835-10 TCGA-CA-6718-10A-01D-1835-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-G4-6321-01A-11D-1719-10 TCGA-G4-6321-10A-01D-1720-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COAD 16 14743686 14743686 + Missense_Mutation SNP G G T TCGA-CK-4947-01B-11D-1650-10 TCGA-CK-4947-10A-01D-1650-10 g.chr16:14743686G>T c.494G>T c.(493-495)aGc>aTc p.S165I COAD 16 14743739 14743739 + Missense_Mutation SNP A A G TCGA-AU-6004-01A-11D-1719-10 TCGA-AU-6004-10A-01D-1719-10 g.chr16:14743739A>G c.547A>G c.(547-549)Acg>Gcg p.T183A COAD 16 14758808 14758808 + Missense_Mutation SNP T T A TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr16:14758808T>A c.1040T>A c.(1039-1041)tTt>tAt p.F347Y COAD 16 14761658 14761658 + Missense_Mutation SNP C C T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr16:14761658C>T c.1327C>T c.(1327-1329)Cgg>Tgg p.R443W COADREAD 16 14738383 14738383 + Silent SNP A A G TCGA-AA-A01Q-01A-01W-A005-10 TCGA-AA-A01Q-10A-01W-A005-10 g.chr16:14738383A>G c.180A>G c.(178-180)ttA>ttG p.L60L COADREAD 16 14742400 14742400 + Missense_Mutation SNP T T G TCGA-AZ-4681-01A-01D-1408-10 TCGA-AZ-4681-10A-01D-1408-10 g.chr16:14742400T>G c.419T>G c.(418-420)aTg>aGg p.M140R COADREAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-AD-6963-01A-11D-1924-10 TCGA-AD-6963-10A-01D-1924-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COADREAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-AF-6136-01A-11D-1826-10 TCGA-AF-6136-10A-01D-1826-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COADREAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-CA-6718-01A-11D-1835-10 TCGA-CA-6718-10A-01D-1835-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COADREAD 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-G4-6321-01A-11D-1719-10 TCGA-G4-6321-10A-01D-1720-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G COADREAD 16 14743686 14743686 + Missense_Mutation SNP G G T TCGA-CK-4947-01B-11D-1650-10 TCGA-CK-4947-10A-01D-1650-10 g.chr16:14743686G>T c.494G>T c.(493-495)aGc>aTc p.S165I COADREAD 16 14743739 14743739 + Missense_Mutation SNP A A G TCGA-AU-6004-01A-11D-1719-10 TCGA-AU-6004-10A-01D-1719-10 g.chr16:14743739A>G c.547A>G c.(547-549)Acg>Gcg p.T183A COADREAD 16 14758808 14758808 + Missense_Mutation SNP T T A TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr16:14758808T>A c.1040T>A c.(1039-1041)tTt>tAt p.F347Y COADREAD 16 14761658 14761658 + Missense_Mutation SNP C C T TCGA-CA-6717-01A-11D-1835-10 TCGA-CA-6717-10A-01D-1835-10 g.chr16:14761658C>T c.1327C>T c.(1327-1329)Cgg>Tgg p.R443W DLBC 16 14738262 14738262 + Missense_Mutation SNP T T C TCGA-FA-A7DS-01A-11D-A382-10 TCGA-FA-A7DS-10A-01D-A385-10 g.chr16:14738262T>C c.59T>C c.(58-60)cTc>cCc p.L20P ESCA 16 14738314 14738314 + Silent SNP C C T TCGA-2H-A9GI-01A-11D-A37C-09 TCGA-2H-A9GI-11A-11D-A37F-09 g.chr16:14738314C>T c.111C>T c.(109-111)tgC>tgT p.C37C GBMLGG 16 14743744 14743744 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:14743744G>A c.552G>A c.(550-552)gcG>gcA p.A184A GBMLGG 16 14761613 14761613 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:14761613T>C c.1282T>C c.(1282-1284)Tac>Cac p.Y428H HNSC 16 14755859 14755859 + Silent SNP C C T TCGA-CN-4723-01A-01D-1434-08 TCGA-CN-4723-10A-01D-1434-08 g.chr16:14755859C>T c.894C>T c.(892-894)ttC>ttT p.F298F KIPAN 16 14755800 14755800 + Missense_Mutation SNP C C G TCGA-B9-4116-01A-01D-1252-08 TCGA-B9-4116-10A-01D-1252-08 g.chr16:14755800C>G c.835C>G c.(835-837)Ccc>Gcc p.P279A KIPAN 16 14755823 14755823 + Silent SNP G G T TCGA-A4-8310-01A-11D-2396-08 TCGA-A4-8310-10A-01D-2396-08 g.chr16:14755823G>T c.858G>T c.(856-858)ctG>ctT p.L286L KIPAN 16 14758841 14758841 + Missense_Mutation SNP C C T TCGA-A4-A7UZ-01A-12D-A34Z-10 TCGA-A4-A7UZ-10A-01D-A34Z-10 g.chr16:14758841C>T c.1073C>T c.(1072-1074)aCa>aTa p.T358I KIRP 16 14755800 14755800 + Missense_Mutation SNP C C G TCGA-B9-4116-01A-01D-1252-08 TCGA-B9-4116-10A-01D-1252-08 g.chr16:14755800C>G c.835C>G c.(835-837)Ccc>Gcc p.P279A KIRP 16 14755823 14755823 + Silent SNP G G T TCGA-A4-8310-01A-11D-2396-08 TCGA-A4-8310-10A-01D-2396-08 g.chr16:14755823G>T c.858G>T c.(856-858)ctG>ctT p.L286L KIRP 16 14758841 14758841 + Missense_Mutation SNP C C T TCGA-A4-A7UZ-01A-12D-A34Z-10 TCGA-A4-A7UZ-10A-01D-A34Z-10 g.chr16:14758841C>T c.1073C>T c.(1072-1074)aCa>aTa p.T358I LGG 16 14743744 14743744 + Silent SNP G G A TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:14743744G>A c.552G>A c.(550-552)gcG>gcA p.A184A LGG 16 14761613 14761613 + Missense_Mutation SNP T T C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr16:14761613T>C c.1282T>C c.(1282-1284)Tac>Cac p.Y428H LUAD 16 14738306 14738306 + Missense_Mutation SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr16:14738306C>T c.103C>T c.(103-105)Cac>Tac p.H35Y LUAD 16 14738323 14738323 + Silent SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr16:14738323C>T c.120C>T c.(118-120)atC>atT p.I40I LUAD 16 14738324 14738324 + Silent SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr16:14738324C>T c.121C>T c.(121-123)Ctg>Ttg p.L41L LUAD 16 14738369 14738369 + Missense_Mutation SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr16:14738369C>T c.166C>T c.(166-168)Cac>Tac p.H56Y LUAD 16 14738414 14738414 + Missense_Mutation SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr16:14738414C>T c.211C>T c.(211-213)Cca>Tca p.P71S LUAD 16 14742340 14742340 + Missense_Mutation SNP A A T TCGA-86-7954-01A-11D-2184-08 TCGA-86-7954-10A-01D-2184-08 g.chr16:14742340A>T c.359A>T c.(358-360)cAg>cTg p.Q120L LUAD 16 14761536 14761536 + Missense_Mutation SNP C C T TCGA-17-Z037-01A-01W-0746-08 TCGA-17-Z037-11A-01W-0746-08 g.chr16:14761536C>T c.1205C>T c.(1204-1206)aCg>aTg p.T402M OV 16 14738296 14738296 + Silent SNP A A G TCGA-29-1761-01A-01W-0633-09 TCGA-29-1761-10A-01W-0633-09 g.chr16:14738296A>G c.93A>G c.(91-93)gaA>gaG p.E31E OV 16 14743686 14743686 + Missense_Mutation SNP G G A TCGA-09-2053-01C-01W-0722-08 TCGA-09-2053-10A-01W-0722-08 g.chr16:14743686G>A c.494G>A c.(493-495)aGc>aAc p.S165N PAAD 16 14738367 14738367 + Missense_Mutation SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr16:14738367G>A c.164G>A c.(163-165)cGt>cAt p.R55H READ 16 14743685 14743685 + Missense_Mutation SNP A A G TCGA-AF-6136-01A-11D-1826-10 TCGA-AF-6136-10A-01D-1826-10 g.chr16:14743685A>G c.493A>G c.(493-495)Agc>Ggc p.S165G SARC 16 14761590 14761590 + Missense_Mutation SNP A A G TCGA-X6-A8C2-01A-11D-A36J-09 TCGA-X6-A8C2-10A-01D-A36M-09 g.chr16:14761590A>G c.1259A>G c.(1258-1260)aAc>aGc p.N420S SKCM 16 14738443 14738443 + Silent SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr16:14738443C>T c.240C>T c.(238-240)ttC>ttT p.F80F SKCM 16 14742418 14742419 + Missense_Mutation DNP CC CC TT TCGA-FS-A4F0-06A-11D-A24R-08 TCGA-FS-A4F0-10A-01D-A24R-08 g.chr16:14742418_14742419CC>TT c.437_438CC>TT c.(436-438)tCC>tTT p.S146F SKCM 16 14755850 14755850 + Silent SNP C C T TCGA-EE-A20C-06A-11D-A196-08 TCGA-EE-A20C-10A-01D-A198-08 g.chr16:14755850C>T c.885C>T c.(883-885)ttC>ttT p.F295F SKCM 16 14761504 14761504 + Silent SNP G G A TCGA-EE-A2GE-06A-11D-A196-08 TCGA-EE-A2GE-10A-01D-A198-08 g.chr16:14761504G>A c.1173G>A c.(1171-1173)caG>caA p.Q391Q

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand 0115_CRUK_PC_0115_T1_DNA COSM5420935 c.115G>A p.D39N Substitution - Missense 16:14644461-14644461 + TCGA-AA-3672-01 COSM266092 c.1040T>A p.F347Y Substitution - Missense 16:14664951-14664951 + YUFERY COSM5384257 c.286C>T p.P96S Substitution - Missense 16:14648410-14648410 + TCGA-D1-A17M-01 COSM967253 c.272T>C p.I91T Substitution - Missense 16:14648396-14648396 + PCSI_0083_Pa_P_526 COSM3377778 c.550G>T p.A184S Substitution - Missense 16:14649885-14649885 + ATL050 COSM5706012 c.391C>A p.P131T Substitution - Missense 16:14648515-14648515 + T3024 COSM4665652 c.349G>T p.A117S Substitution - Missense 16:14648473-14648473 + TCGA-BR-8680-01 COSM2143989 c.942C>T p.I314I Substitution - coding silent 16:14662050-14662050 + STC252 COSM5054661 c.114C>T p.Y38Y Substitution - coding silent 16:14644460-14644460 + SNUH_G10_S1 COSM3999716 c.419T>C p.M140T Substitution - Missense 16:14648543-14648543 + 12T COSM107859 c.120C>T p.I40I Substitution - coding silent 16:14644466-14644466 + TCGA-BH-A0B6-01 COSM3817232 c.1246C>T p.Q416* Substitution - Nonsense 16:14667720-14667720 + TCGA-AX-A0J0-01 COSM967260 c.1103T>C p.L368S Substitution - Missense 16:14665014-14665014 + LUAD-TLLGS COSM347550 c.795A>G p.P265P Substitution - coding silent 16:14661903-14661903 + SC_9035 COSM5573550 c.783+2T>G p.? Unknown 16:14655212-14655212 + ESO-838 COSM1246088 c.1029G>A p.L343L Substitution - coding silent 16:14664940-14664940 + 228 COSM2143975 c.164G>A p.R55H Substitution - Missense 16:14644510-14644510 + TCGA-D8-A1JP-01 COSM1478533 c.643C>G p.L215V Substitution - Missense 16:14655070-14655070 + TCGA-CA-6717-01 COSM1376007 c.1327C>T p.R443W Substitution - Missense 16:14667801-14667801 + PCSI_0083_Pa_P COSM3377778 c.550G>T p.A184S Substitution - Missense 16:14649885-14649885 + TCGA-AU-6004-01 COSM1376006 c.547A>G p.T183A Substitution - Missense 16:14649882-14649882 + 2521249 COSM5888273 c.1270T>A p.Y424N Substitution - Missense 16:14667744-14667744 + HT29 COSM2143974 c.138C>T p.T46T Substitution - coding silent 16:14644484-14644484 + PTC_448 COSM5959385 c.1234C>T p.P412S Substitution - Missense 16:14667708-14667708 + TCGA-09-2053-01 COSM69818 c.494G>A p.S165N Substitution - Missense 16:14649829-14649829 + CSCC-60-T COSM4456698 c.1019C>T p.P340L Substitution - Missense 16:14664930-14664930 + CSCC-31-T COSM4562570 c.932G>A p.G311E Substitution - Missense 16:14662040-14662040 + TCGA-AP-A059-01 COSM967261 c.1168C>T p.P390S Substitution - Missense 16:14667642-14667642 + TCGA-EK-A3GK-01 COSM4852920 c.769C>A p.L257I Substitution - Missense 16:14655196-14655196 + 13 COSM5732820 c.1267_1268insT p.Y424fs*7 Insertion - Frameshift 16:14667741-14667742 + T3094 COSM4665653 c.561T>C p.V187V Substitution - coding silent 16:14649896-14649896 + TCGA-E2-A15M-01 COSM434668 c.113A>C p.Y38S Substitution - Missense 16:14644459-14644459 + TCGA-C5-A1M8-01 COSM4837264 c.730G>C p.E244Q Substitution - Missense 16:14655157-14655157 + TCGA-A4-8310-01 COSM3988246 c.858G>T p.L286L Substitution - coding silent 16:14661966-14661966 + TCGA-36-1569-01 COSM112050 c.756_757insC p.Q255fs*7 Insertion - Frameshift 16:14655183-14655184 + TCGA-B1-A655-01 COSM4414831 c.261C>T p.L87L Substitution - coding silent 16:14644607-14644607 + 46M COSM5587288 c.1352G>A p.*451* Substitution - coding silent 16:14667826-14667826 + TCGA-BR-4257-01 COSM4058460 c.1110A>G p.S370S Substitution - coding silent 16:14665021-14665021 + LUAD-RT-S01808 COSM382679 c.1062C>T p.V354V Substitution - coding silent 16:14664973-14664973 + HCT8 COSM2143985 c.814C>T p.L272L Substitution - coding silent 16:14661922-14661922 + TCGA-BK-A0C9-01 COSM967255 c.688A>T p.I230L Substitution - Missense 16:14655115-14655115 + AOCS-091-1-3 COSM3944372 c.264-4A>C p.? Unknown 16:14648384-14648384 + TCGA-A5-A0VP-01 COSM967254 c.513C>T p.H171H Substitution - coding silent 16:14649848-14649848 + TCGA-29-1761-01 COSM1323715 c.93A>G p.E31E Substitution - coding silent 16:14644439-14644439 + TCGA-AP-A059-01 COSM967258 c.902C>T p.T301I Substitution - Missense 16:14662010-14662010 + CHEWS029 COSM4578691 c.474C>T p.V158V Substitution - coding silent 16:14649809-14649809 + tumor_4131095 COSM5948666 c.682T>A p.Y228N Substitution - Missense 16:14655109-14655109 + TCGA-CG-5723-01 COSM4058459 c.514G>A p.D172N Substitution - Missense 16:14649849-14649849 + SNUH_G76_S1 COSM4418934 c.113A>G p.Y38C Substitution - Missense 16:14644459-14644459 + SC_9043 COSM5559349 c.1016T>C p.L339P Substitution - Missense 16:14664927-14664927 + S01366 COSM309473 c.1242delC p.P415fs*>36 Deletion - Frameshift 16:14667716-14667716 + TCGA-EE-A2GE-06 COSM3506126 c.1173G>A p.Q391Q Substitution - coding silent 16:14667647-14667647 + T6 COSM1376003 c.419T>G p.M140R Substitution - Missense 16:14648543-14648543 + BD236T COSM5135417 c.1214delT p.F406fs*>45 Deletion - Frameshift 16:14667688-14667688 + TCGA-FW-A3R5-06 COSM3887934 c.240C>T p.F80F Substitution - coding silent 16:14644586-14644586 + DLD1 COSM4623239 c.331G>A p.D111N Substitution - Missense 16:14648455-14648455 + 587342 COSM1184677 c.1247A>G p.Q416R Substitution - Missense 16:14667721-14667721 + TCGA-BR-7707-01 COSM4058458 c.329A>G p.N110S Substitution - Missense 16:14648453-14648453 + TCGA-BS-A0UJ-01 COSM967256 c.838A>G p.R280G Substitution - Missense 16:14661946-14661946 + TCGA-B0-4707-01 COSM2143991 c.958G>A p.D320N Substitution - Missense 16:14664869-14664869 + TCGA-A5-A0GH-01 COSM967257 c.877G>A p.D293N Substitution - Missense 16:14661985-14661985 + HCT15 COSM2143985 c.814C>T p.L272L Substitution - coding silent 16:14661922-14661922 + T2932 COSM4665654 c.1122A>G p.L374L Substitution - coding silent 16:14665033-14665033 + DLD1 COSM2143985 c.814C>T p.L272L Substitution - coding silent 16:14661922-14661922 + ESO-161 COSM1246087 c.303G>T p.L101L Substitution - coding silent 16:14648427-14648427 + 234 COSM967254 c.513C>T p.H171H Substitution - coding silent 16:14649848-14649848 + TCGA-CF-A3MG-01 COSM1301644 c.658G>A p.E220K Substitution - Missense 16:14655085-14655085 + TCGA-CF-A27C-01 COSM1301645 c.771C>T p.L257L Substitution - coding silent 16:14655198-14655198 + CSCC-31-T COSM4509553 c.810C>T p.F270F Substitution - coding silent 16:14661918-14661918 + TCGA-BK-A0C9-01 COSM967259 c.929C>T p.S310F Substitution - Missense 16:14662037-14662037 + LOVO COSM4614149 c.757delC p.Q255fs*9 Deletion - Frameshift 16:14655184-14655184 + PCSI_0083_Pa_X COSM3377778 c.550G>T p.A184S Substitution - Missense 16:14649885-14649885 + T3080 COSM112050 c.756_757insC p.Q255fs*7 Insertion - Frameshift 16:14655183-14655184 + TCGA-EE-A20C-06 COSM3506125 c.885C>T p.F295F Substitution - coding silent 16:14661993-14661993 + S01366 COSM309473 c.1242delC p.P415fs*>36 Deletion - Frameshift 16:14667716-14667716 + SCMC_RM2_ COSM4989005 c.1079G>A p.R360Q Substitution - Missense 16:14664990-14664990 + CSCC-44-T COSM4555602 c.661G>A p.E221K Substitution - Missense 16:14655088-14655088 + tumor_4131095 COSM5948705 c.746T>C p.L249S Substitution - Missense 16:14655173-14655173 + TCGA-FD-A3SN-01 COSM3794584 c.76C>T p.Q26* Substitution - Nonsense 16:14644422-14644422 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.435556 16p13.12

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.Q107P c.320A>C 16 14742301 STAD A C Missense p.Y38S c.113A>C 16 14738316 BRCA A G Synonymous p.S370S c.1110A>G 16 14758878 STAD C - Frameshift p.P415Lfs*43 c.1244delC 16 14761573 SCLC - C Frameshift p.Q255Pfs*7 c.763dupC 16 14749041 OV C G Missense p.L215V c.643C>G 16 14748927 BRCA C T IntronicSNV . c.1161-56C>T 16 14761436 CM C T Missense p.S310F c.929C>T 16 14755894 UCEC C T Missense p.T402M c.1205C>T 16 14761536 LUAD C T Synonymous p.F295F c.885C>T 16 14755850 CM C T Synonymous p.H171H c.513C>T 16 14743705 UCEC C T Synonymous p.L257L c.771C>T 16 14749055 BLCA G A Missense p.D293N c.877G>A 16 14755842 UCEC G A Missense p.D320N c.958G>A 16 14758726 RCCC G A Missense p.E220K c.658G>A 16 14748942 BLCA G A Missense p.S165N c.494G>A 16 14743686 OV G A Synonymous p.L343L c.1029G>A 16 14758797 ESCA G A Synonymous p.Q391Q c.1173G>A 16 14761504 CM GG TT Missense p.G50L c.148_149delinsTT 16 14738351 CM G T Synonymous p.L101L c.303G>T 16 14742284 ESCA T C Missense p.I91T c.272T>C 16 14742253 UCEC TT - Frameshift p.F429*fs*1 c.1286_1287delTT 16 14761616 THCA