PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRAF3IP2 RIMBP3 25416956 biogrid,intact exp DTX2 RIMBP3 25416956,21516116 biogrid,intact exp CREB5 RIMBP3 25416956 biogrid,intact exp ZNF488 RIMBP3 25416956 biogrid,intact exp PRKAB2 RIMBP3 25416956,24722188 biogrid,intact exp AQP1 RIMBP3 25416956 innatedb,biogrid,intact exp RIMBP3 PPIL1 25416956 biogrid,intact exp CATSPER1 RIMBP3 25416956 biogrid,intact exp PRKAA1 RIMBP3 25416956 biogrid,intact exp POLR1C RIMBP3 25416956 biogrid,intact exp DGCR6 RIMBP3 24722188 biogrid exp MVP RIMBP3 24722188 biogrid exp CTBP2 RIMBP3 25416956 biogrid,intact exp AES RIMBP3 25416956 innatedb,biogrid,intact exp DGCR6L RIMBP3 25416956 biogrid,intact exp FANCL RIMBP3 25416956 biogrid,intact exp ARNT2 RIMBP3 24722188 biogrid exp NOXA1 RIMBP3 25416956, 23023127 biogrid,intact exp, pred NGEF RIMBP3 23023127 pred PIK3R2 RIMBP3 23023127 pred SAMSN1 RIMBP3 23023127 pred BAIAP2L2 RIMBP3 23023127 pred UBASH3B RIMBP3 23023127 pred MIA RIMBP3 23023127 pred ARHGEF6 RIMBP3 23023127 pred RIMBP3 SH3GLB1 23023127 pred ARHGAP4 RIMBP3 23023127 pred SPIN4 RIMBP3 23023127 pred VAV1 RIMBP3 23023127 pred RIMBP3B RIMBP3 23023127 pred SH2D7 RIMBP3 23023127 pred GRAP RIMBP3 23023127 pred CRK RIMBP3 23023127 pred RIMBP3C RIMBP3 23023127 pred SH3GLB2 RIMBP3 23023127 pred SH3GL2 RIMBP3 23023127 pred SH3RF1 RIMBP3 23023127 pred PSTPIP1 RIMBP3 23023127 pred PLCG1 RIMBP3 23023127 pred HERPUD1 RIMBP3 23023127 pred NCF2 RIMBP3 23023127 pred STAM RIMBP3 23023127 pred BZRAP1 RIMBP3 23023127 pred MATK RIMBP3 23023127 pred UBXN10 RIMBP3 23023127 pred HCLS1 RIMBP3 23023127 pred MLK4 RIMBP3 23023127 pred ARHGEF16 RIMBP3 23023127 pred MIA2 RIMBP3 23023127 pred ARHGEF37 RIMBP3 23023127 pred RIMBP3 SH2B3 23023127 pred MIDN RIMBP3 23023127 pred ITSN1 RIMBP3 23023127 pred RASA1 RIMBP3 23023127 pred PLCG2 RIMBP3 23023127 pred TRIO RIMBP3 23023127 pred SH2B1 RIMBP3 23023127 pred RIMBP3 PACSIN3 23023127 pred RIMBP3 SCML2 23023127 pred PHF20L1 RIMBP3 23023127 pred PACSIN1 RIMBP3 23023127 pred MAP3K11 RIMBP3 23023127 pred STAM2 RIMBP3 23023127 pred SH3RF3 RIMBP3 23023127 pred SH3KBP1 RIMBP3 23023127 pred SUMO4 RIMBP3 23023127 pred GRAP2 RIMBP3 23023127 pred RIMBP3 BAIAP2 23023127 pred NEDD9 RIMBP3 23023127 pred RGS14 RIMBP3 23023127 pred HCK RIMBP3 23023127 pred RUSC1 RIMBP3 23023127 pred EPS8L3 RIMBP3 23023127 pred SH3PXD2A RIMBP3 23023127 pred SASH3 RIMBP3 23023127 pred ORC1 RIMBP3 23023127 pred TP53BP1 RIMBP3 23023127 pred PEX13 RIMBP3 23023127 pred TDRD1 RIMBP3 23023127 pred SMN1, SMN2 RIMBP3 23023127 pred STAC RIMBP3 23023127 pred LASP1 RIMBP3 23023127 pred NCK2 RIMBP3 23023127 pred EFS RIMBP3 23023127 pred ITK RIMBP3 23023127 pred MAPK8IP2 RIMBP3 23023127 pred VAV2 RIMBP3 23023127 pred SPTAN1 RIMBP3 23023127 pred RIMBP3 RIMBP3 23023127 pred ABI2 RIMBP3 23023127 pred GRB10 RIMBP3 23023127 pred ASPSCR1 RIMBP3 23023127 pred EPS8L1 RIMBP3 23023127 pred ARID4B RIMBP3 23023127 pred RIMBP3 BAIAP2L1 23023127 pred PPP1R13L RIMBP3 23023127 pred FYN RIMBP3 23023127 pred ARHGEF9 RIMBP3 23023127 pred BTK RIMBP3 23023127 pred CTTN RIMBP3 23023127 pred FRMD7 RIMBP3 23023127 pred HERPUD2 RIMBP3 23023127 pred RIMBP3 MTF2 23023127 pred MYO1E RIMBP3 23023127 pred SORBS1 RIMBP3 23023127 pred PHF20 RIMBP3 23023127 pred ARID4A RIMBP3 23023127 pred ABL2 RIMBP3 23023127 pred PSIP1 RIMBP3 23023127 pred CACNB4 RIMBP3 23023127 pred SRGAP1 RIMBP3 23023127 pred SNX18 RIMBP3 23023127 pred SH3BP4 RIMBP3 23023127 pred RIMBP3 DBNL 23023127 pred FCHSD2 RIMBP3 23023127 pred BCAR1 RIMBP3 23023127 pred RIMBP3 ARHGAP26 23023127 pred STAC2 RIMBP3 23023127 pred NCF4 RIMBP3 23023127 pred NCF4 RIMBP3 23023127 pred SLA2 RIMBP3 23023127 pred SOCS6 RIMBP3 23023127 pred PIK3R1 RIMBP3 23023127 pred OTOR RIMBP3 23023127 pred UBASH3A RIMBP3 23023127 pred SH3PXD2B RIMBP3 23023127 pred CACNB2 RIMBP3 23023127 pred OSTF1 RIMBP3 23023127 pred RIMBP3 CD2AP 23023127 pred SYK RIMBP3 23023127 pred BAG6 RIMBP3 23023127 pred SASH1 RIMBP3 23023127 pred CASS4 RIMBP3 23023127 pred SH3YL1 RIMBP3 23023127 pred HDGFRP2 RIMBP3 23023127 pred CACNB3 RIMBP3 23023127 pred ARHGEF7 RIMBP3 23023127 pred CRKL RIMBP3 23023127 pred DNMBP RIMBP3 23023127 pred GRB7 RIMBP3 23023127 pred NPHP1 RIMBP3 23023127 pred LCK RIMBP3 23023127 pred SKAP1 RIMBP3 23023127 pred AHI1 RIMBP3 23023127 pred ITSN2 RIMBP3 23023127 pred EPS8L2 RIMBP3 23023127 pred BIN1 RIMBP3 23023127 pred ABL1 RIMBP3 23023127 pred NOXO1 RIMBP3 23023127 pred RNF17 RIMBP3 23023127 pred RIMBP3 ASAP1 23023127 pred SORBS3 RIMBP3 23023127 pred GRB2 RIMBP3 23023127 pred UBC RIMBP3 23023127 pred SH3GL1 RIMBP3 23023127 pred ABI1 RIMBP3 23023127 pred RIMBP3 GMEB1 23023127 pred MUM1 RIMBP3 23023127 pred RIMBP3 SPIN1 23023127 pred MYO1F RIMBP3 23023127 pred MYO15B RIMBP3 23023127 pred TEC RIMBP3 23023127 pred NCK1 RIMBP3 23023127 pred ARHGEF19 RIMBP3 23023127 pred GRB14 RIMBP3 23023127 pred SH2D1A RIMBP3 23023127 pred NOSTRIN RIMBP3 23023127 pred OBSCN RIMBP3 23023127 pred FYB RIMBP3 23023127 pred RIMBP2 RIMBP3 23023127 pred SRGAP2 RIMBP3 23023127 pred SRMS RIMBP3 23023127 pred PPP1R13B RIMBP3 23023127 pred RUSC2 RIMBP3 23023127 pred MAP3K10 RIMBP3 23023127 pred TRIP10 RIMBP3 23023127 pred SRGAP3 RIMBP3 23023127 pred ABI3 RIMBP3 23023127 pred RIMBP3 SNX9 23023127 pred CIDEC RIMBP3 23023127 pred LYN RIMBP3 23023127 pred TP53BP2 RIMBP3 23023127 pred RIMBP3 MAPK8IP1 23023127 pred SH3RF2 RIMBP3 23023127 pred KALRN RIMBP3 23023127 pred STAC3 RIMBP3 23023127 pred FRK RIMBP3 23023127 pred SH3D21 RIMBP3 23023127 pred SH3GL3 RIMBP3 23023127 pred SGSM3 RIMBP3 23023127 pred MIA3 RIMBP3 23023127 pred UBXN11 RIMBP3 23023127 pred UBFD1 RIMBP3 23023127 pred PRMT2 RIMBP3 23023127 pred BAHD1 RIMBP3 23023127 pred AMPH RIMBP3 23023127 pred SORBS2 RIMBP3 23023127 pred SPIN2A RIMBP3 23023127 pred CEP350 RIMBP3 23023127 pred SUPT5H RIMBP3 23023127 pred CIDEA RIMBP3 23023127 pred RIMBP3 MYO15A 23023127 pred YES1 RIMBP3 23023127 pred FCHSD1 RIMBP3 23023127 pred MAP3K9 RIMBP3 23023127 pred RIMBP3 VAV3 23023127 pred NEB RIMBP3 23023127 pred NEBL RIMBP3 23023127 pred SLA RIMBP3 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q86UR1-2 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q9UFD9 Q14764 two hybrid 24722188 direct interaction X 2 Q9UFD9 P56545-2 two hybrid 25416956 direct interaction X 2 Q9UFD9 O15160 two hybrid 25416956 direct interaction X 2 Q9UFD9 Q9BY27 two hybrid 25416956 direct interaction X 2 Q08117 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q96MN9 Q9UFD9 two hybrid 25416956 direct interaction X 2 A0A024RCX8 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q8NEC5 Q9UFD9 two hybrid 25416956 direct interaction X 2 O43741 Q9UFD9 two hybrid 24722188 direct interaction X 2 O43741 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q9UFD9 Q9HBZ2 two hybrid 24722188 direct interaction X 2 Q9UFD9 Q14129 two hybrid 24722188 direct interaction X 2 Q9UFD9 P29972-3 two hybrid 25416956 direct interaction X 2 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q9UFD9 Q02930 two hybrid 25416956 direct interaction X 2 Q9UFD9 O43734-2 two hybrid 25416956 direct interaction X 2 Q9UFD9 two hybrid 25416956 direct interaction X 2 Q9UFD9 Q86UW9 two hybrid 25416956 direct interaction X 2 Q9NW38 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q9NW38 Q9UFD9 two hybrid array 25416956 physical association X 2 Q9NW38 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q86UR1 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q86UR1 Q9UFD9 two hybrid array 25416956 physical association X 2 Q86UR1 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q9UFD9 O15160 two hybrid prey pooling approach 25416956 physical association X 2 Q9UFD9 O43734 two hybrid prey pooling approach 25416956 physical association X 2 Q9UFD9 Q9BY27 two hybrid prey pooling approach 25416956 physical association X 2 Q9UFD9 O15160 two hybrid array 25416956 physical association X 2 Q9UFD9 O43734 two hybrid array 25416956 physical association X 2 Q9UFD9 Q9BY27 two hybrid array 25416956 physical association X 2 Q9UFD9 O15160 validated two hybrid 25416956 physical association X 2 Q9UFD9 O43734 validated two hybrid 25416956 physical association X 2 Q9UFD9 Q9BY27 validated two hybrid 25416956 physical association X 2 Q08117 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q08117 Q9UFD9 two hybrid array 25416956 physical association X 2 Q08117 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q96MN9 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q96MN9 Q9UFD9 two hybrid array 25416956 physical association X 2 Q96MN9 Q9UFD9 validated two hybrid 25416956 physical association X 2 A0A024RCX8 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 A0A024RCX8 Q9UFD9 two hybrid array 25416956 physical association X 2 A0A024RCX8 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q8NEC5 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q8NEC5 Q9UFD9 two hybrid array 25416956 physical association X 2 Q8NEC5 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q8IY44 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q8IY44 Q9UFD9 two hybrid array 25416956 physical association X 2 Q8IY44 Q9UFD9 validated two hybrid 25416956 physical association X 2 A0A024RA31 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 A0A024RA31 Q9UFD9 two hybrid array 25416956 physical association X 2 A0A024RA31 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q13131 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q13131 Q9UFD9 two hybrid array 25416956 physical association X 2 Q13131 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q4ZH49 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 Q4ZH49 Q9UFD9 two hybrid array 25416956 physical association X 2 Q4ZH49 Q9UFD9 validated two hybrid 25416956 physical association X 2 O43741 Q9UFD9 two hybrid prey pooling approach 25416956 physical association X 2 O43741 Q9UFD9 two hybrid array 25416956 physical association X 2 O43741 Q9UFD9 validated two hybrid 25416956 physical association X 2 Q9UFD9 Q02930-3 two hybrid prey pooling approach 25416956 physical association X 2 Q9UFD9 Q02930-3 two hybrid array 25416956 physical association X 2 Q9UFD9 Q02930-3 validated two hybrid 25416956 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality POLR1C RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRAF3IP2 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT PRKAB2 RIMBP3 25416956,25416956,25416956,25416956,24722188 1356,1112,0397,0018,0018 HT AQP1 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CTBP2 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT CREB5 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT AES RIMBP3 25416956,25416956,25416956 1112,0397,1356 HT PRKAA1 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DGCR6 RIMBP3 24722188 0018 HT MVP RIMBP3 24722188 0018 HT NOXA1 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DTX2 RIMBP3 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT CATSPER1 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT PP2150 RIMBP3 25416956 0018 HT ZNF488 RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT DGCR6L RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ARNT2 RIMBP3 24722188 0018 HT FANCL RIMBP3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RIMBP3 PPIL1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UFD9 Q9HBZ2 RIMBP3 ARNT2 0.183 24722188 Q9UFD9 Q9P0T4 RIMBP3 ZNF581 0.236 unassigned1304 Q9UFD9 Q9HC98 RIMBP3 NEK6 0.236 unassigned1304 Q9UFD9 Q9NQ94 RIMBP3 A1CF 0.236 unassigned1304 Q9UFD9 Q9NW38 RIMBP3 FANCL 0.454 25416956 Q9UFD9 O43741 RIMBP3 PRKAB2 0.554 25416956,24722188 Q9UFD9 O15160 RIMBP3 POLR1C 0.583 25416956,unassigned1304 Q9UFD9 J3KQ70 RIMBP3 INO80B-WBP1 {ECO:0000313|ENSEMBL:ENSP00000388677} 0.236 unassigned1304 Q9UFD9 A0A0C4DH14 RIMBP3 C22ORF39 {ECO:0000313|ENSEMBL:ENSP00000333064} 0.236 unassigned1304 Q9UFD9 O95363 RIMBP3 FARS2 0.236 unassigned1304 Q9UFD9 Q13131 RIMBP3 PRKAA1 0.454 25416956 Q9UFD9 Q96MN9 RIMBP3 ZNF488 0.454 25416956 Q9UFD9 Q8TCE9 RIMBP3 LGALS14 0.236 unassigned1304 Q9UFD9 Q96A09 RIMBP3 FAM46B 0.236 unassigned1304 Q9UFD9 Q17RB8 RIMBP3 LONRF1 0.236 unassigned1304 Q9UFD9 O43559 RIMBP3 FRS3 0.236 unassigned1304 Q9UFD9 Q7Z5V6 RIMBP3 PPP1R32 0.236 unassigned1304 Q9UFD9 O95872 RIMBP3 GPANK1 0.236 unassigned1304 Q9UFD9 Q86UR1 RIMBP3 NOXA1 0.583 25416956,unassigned1304 Q9UFD9 Q5JVL4 RIMBP3 EFHC1 0.332 25910212 Q9UFD9 Q08117 RIMBP3 AES 0.454 25416956 Q9UFD9 Q8NEC5 RIMBP3 CATSPER1 0.454 25416956 Q9UFD9 Q9BY27 RIMBP3 DGCR6L 0.454 25416956 Q9UFD9 O43734 RIMBP3 TRAF3IP2 0.454 25416956 Q9UFD9 P23059 RIMBP3 MAK31 0.332 27107014 Q9UFD9 P29972 RIMBP3 AQP1 0.454 25416956 Q9UFD9 P47041 RIMBP3 BIT61 0.332 27107014 Q9UFD9 Q02930 RIMBP3 CREB5 0.454 25416956 Q9UFD9 Q86UW9 RIMBP3 DTX2 0.332 21516116,25416956 Q9UFD9 Q8IY44 RIMBP3 CTBP2 {ECO:0000313|EMBL:AAH37900.1} 0.332 25416956 Q9Y3C6 Q9UFD9 PPIL1 RIMBP3 0.454 25416956 Q9UFD9 Q14129 RIMBP3 DGCR6 0.183 24722188 Q9UFD9 Q14764 RIMBP3 MVP 0.183 24722188 Q9UFD9 P42937 RIMBP3 YCH1 0.332 27107014 Q9UFD9 Q4ZH49 RIMBP3 DTX2 {ECO:0000313|EMBL:AAY27263.1} 0.332 25416956 Q9UFD9 P56545 RIMBP3 CTBP2 0.183 25416956

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 POLR1C RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database TRAF3IP2 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database PRKAB2 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database AQP1 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database CTBP2 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database CREB5 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database AES RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database PRKAA1 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database DGCR6 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database MVP RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database NOXA1 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database DTX2 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database CATSPER1 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database ZNF488 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database DGCR6L RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database ARNT2 RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database FANCL RIMBP3 MI:0045 experimental interaction detection MI:0461 interaction database RIMBP3 PPIL1 MI:0045 experimental interaction detection MI:0461 interaction database