PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UHRF1 RNF2 24457600 biogrid exp G PML UHRF1 22945642 biogrid exp G G G G G G G G G G G G G G G CCNDBP1 UHRF1 26186194 biogrid exp G G G G G G G G G G G G G G G UHRF1BP1 UHRF1 15361834 biogrid exp G G G G G G G G G G G G G G G OBSL1 UHRF1 24711643 biogrid exp G G G G G G G G G G G G G ZPR1 UHRF1 22939629 biogrid exp G G G G G G G G G G G G G G G UHRF1 TRPV5 26186194 biogrid exp G G G G G G G G G G G HIST3H3 UHRF1 23161542,24813945,23281010,22100450,26065575,23752590 biogrid exp NTRK1 UHRF1 25921289 biogrid exp G USP11 UHRF1 22411829 biogrid exp G G G G G G G G G G G G G G G MBD4 UHRF1 25358258 biogrid exp G G G G G G G G G G G G G G G AHSA1 UHRF1 26693507 biogrid exp G G G G G G G G G G G G G G G ERCC1 UHRF1 25818288 biogrid exp G G G G G G G G G G G G G G G PRKACA UHRF1 15178447 biogrid exp G G G G G G G G G G G G G G G HIST1H2BB UHRF1 14993289 hprd exp KAT5 UHRF1 23677994,21045206,19800870 biogrid exp G G G G G G G G G G G G G G G SUZ12 UHRF1 22330138 biogrid exp G G G G G G G G G G G G G G G HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI UHRF1 25281560 biogrid exp G G G G G G G G G G G G G G G RPL10 UHRF1 26496610 biogrid,intact exp CUL1 UHRF1 23297342 biogrid exp G G G G G G G G G G G G G G G HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 UHRF1 14993289 hprd exp TCEAL1 UHRF1 26186194,19615732 biogrid,intact exp G G G G G G G G G G G G G G G PCNA UHRF1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G UHRF1 BTRC 23297342 biogrid exp G G G G G G G G G G G G G G G MPG UHRF1 23537643 biogrid exp G G G G G G G G G G G G G G G UQCRB UHRF1 26186194 biogrid exp G G G G G G G G G G G G G G G UHRF1 CCDC8 24711643 biogrid exp G G G G G G G G G G G G G G G HNRNPU UHRF1 26496610 biogrid,intact exp G G G G G G G G G G G G G G G WIPI1 UHRF1 26186194 biogrid exp G G G G G G G G G G G G G G G USP7 UHRF1 24013172,23297342,21268065,21745816,26496610,22411829 biogrid,intact exp G G G G G G G G G G G G G G G ERCC4 UHRF1 25818288 biogrid exp G G G G G G G G G G G G G G G ELAVL1 UHRF1 19322201 biogrid exp G G G G G G G G G G G G G G G HIST2H3A, HIST2H3C, HIST2H3D UHRF1 21489993,22837395,22294699,23022729 biogrid exp UHRF2 UHRF1 22411829 biogrid exp G G G G G G G G G G G G G G G DBN1 UHRF1 26496610 biogrid,intact exp G G G G G G G G G G G G G G UHRF1 PARP2 24782312 biogrid exp G G G G G G G G G G G G G G G EHMT2 UHRF1 22064703,19056828,19943104 biogrid exp G G G G G G G G G G G G G G G UHRF1 UHRF1 23161542,24782312,17967883 biogrid exp, ortho G G G G G G G G G G G G G G G DNMT1 UHRF1 22064703,17934516,21745816,19800870,19943104,24368767,21268065,24782312,19798101,20613874,17673620,21045206,26065575, 25402006, 21836163 biogrid,mint,intact exp, ortho, pred G G G G G G G G G G G G G G G HIST1H2AB, HIST1H2AE UHRF1 14993289, 25402006 hprd exp, ortho, pred G G G HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J UHRF1 22064703,25281560,17967883,14993289, 25402006 hprd,biogrid exp, ortho, pred G G G G MUS81 UHRF1 25818288, 25402006 biogrid exp, ortho, pred G G G G G G G G G G G G G G G EME1 UHRF1 25818288, 25402006 biogrid exp, ortho, pred G G G G G G G G G G G G G G G PARP1 UHRF1 24782312, 23023127 biogrid exp, ortho, pred G G G G G G G G G G G G G G G TOP2A UHRF1 25451918, 25402006 biogrid exp, ortho, pred G G G G G G G G G G HDAC1 UHRF1 17934516,15361834,19800870,22411829, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G UHRF1 DNMT3B 22064703,19798101, 25402006 biogrid,mint,intact exp, pred G G G G G G G G G G G G SUV39H1 UHRF1 22330138, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G EZH2 UHRF1 22330138, 25402006 biogrid exp, pred G G G G G G G G G G G TRIM28 UHRF1 22055183, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G UHRF1 DNMT3A 22064703,19798101,21745816, 25402006 biogrid,mint,intact exp, pred G G G G G G G G G G G G G G G RB1 UHRF1 16007129, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G RNF4 UHRF1 21252943, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G RCC1 UHRF1 ortho G G G G G G G G G G G G G G G UHRF1 SUPT16H ortho G G G G G G G G G G G G G G G HIST1H2AD UHRF1 ortho TOP2B UHRF1 ortho G G G G G G G G G G G G G G G UHRF1 NANOG ortho G ATM UHRF1 ortho G G G G G G G G G G G G G G G UHRF1 DTL 25402006 pred G G G G G G G G G SUMO1 UHRF1 25402006, 23023127 pred G G G G G G G G G G G G G G G UHRF1 RAD9A 25402006 pred G G G G G G G G G G G G G G G DTX3L UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 ZBTB18 25402006 pred G G G G G G G G G G G G G G G UHRF1 DAXX 25402006 pred G G G G G G G G G G G G G G G E2F1 UHRF1 25402006, 21836163 pred G G G G G G G G G G G G STAT3 UHRF1 25402006 pred G G G G G G G G G G G G G G G UHRF1 BRIP1 25402006 pred G G G G G CHFR UHRF1 25402006 pred G G G G G G G G G G G G G G G UHRF1 DMAP1 25402006 pred G G G G G G G G RAD23A UHRF1 23023127 pred G G G G G G G G G G G G G G G MAP2K5 UHRF1 23023127 pred G G G G G G G G G G G G G G PDC UHRF1 21836163 pred RFWD3 UHRF1 23023127 pred G G G G G G G G G G G G ASMT UHRF1 21836163 pred PLK1 UHRF1 23023127 pred G G G G G G G G G G G UBE2S UHRF1 23023127 pred G G G G G G G G G G G G G G UBE2G2 UHRF1 23023127 pred G G G G G G G G G G G G G G G TRIM11 UHRF1 21836163 pred G G G G G G G G G G G G G G G CDK1 UHRF1 25402006 pred G G G G G G G G G G G G UBE2G1 UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 HDAC9 25402006 pred G G G G G G G G G G G G G UBE2N UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 UBQLN3 23023127 pred G G G G UHRF1 TPX2 25402006 pred G G G G G G G G G G G G G G TDG UHRF1 23023127 pred G G G G G G G G G G G G G G G GTF2H2 UHRF1 23023127 pred G G G G G G G G G G G G G G G PBK UHRF1 25402006 pred G G G G G G G HNRNPK UHRF1 23023127 pred PIAS2 UHRF1 25402006 pred G G G G G G G G G G G G G G G UHRF1 KIF15 25402006 pred G G G G G G G KIAA0101 UHRF1 25402006 pred G G G G G G G G G G G G G G G TMEM97 UHRF1 25402006 pred G G G G G G G G G G G G G G G SETD7 UHRF1 25402006 pred G G G G G G G G G G G G G G G BUB1B UHRF1 25402006 pred G G G G G G G G G G G UHRF1 NUSAP1 25402006 pred G G G G G G G G G G G G G G UHRF1 UBE2T 23023127 pred G G G G G G G G UHRF1 FANCL 21836163 pred G G G G G G G G G G G G G G G UHRF1 RACGAP1 25402006 pred G G G G G G G G G G G G G G G UHRF1 TACC3 25402006 pred G G G G G G G G G UHRF1 NR2E3 25402006 pred CBX5 UHRF1 25402006 pred G G G G G G G G G G G G G G G RAN UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 FANCI 25402006 pred G G G G G G G G G G G G G G BRAP UHRF1 21836163 pred G G G G G G G RNF144B UHRF1 21836163 pred G G G G G G G G G G G G G G G UHRF1 SAE1 23023127 pred G G G G G G G G G G G G G G G UBA1 UHRF1 16082366 pred G G G G G G G G G G G G G G G WHSC1 UHRF1 25402006 pred G G G G G G G G G G G G G NCAPH UHRF1 25402006 pred G G G G UHRF1 KIF2C 25402006 pred G G G G G G G G G G G G G G G TCEB1 UHRF1 23023127 pred G G G G G G G G G G G G G G G NPM1 UHRF1 25402006 pred G G G G G G G G G G G G G G G SP1 UHRF1 25402006 pred G G G G G G G G G G G G G G G KIF4A UHRF1 25402006 pred G G G G G G G G UBE2L3 UHRF1 23023127 pred G G G G G G G G G G G G G G G UBC UHRF1 23023127 pred UHRF1 BARD1 23023127 pred G G G G G G G G G ALDH7A1 UHRF1 21836163 pred G G G G G G G G G G G G G G G ASPM UHRF1 25402006 pred G G G G UHRF1 RASSF1 23023127 pred G G G G G G G G G G G G G G G LRSAM1 UHRF1 21836163 pred G G G G G G HERPUD1 UHRF1 23023127 pred G G G G G G G G G G G G G G G RNASEH2A UHRF1 25402006 pred G G G G G G G G G G G G G G G PIAS1 UHRF1 25402006 pred G G G G G G G G G G G G G G G NUDT1 UHRF1 23023127 pred G G G G KIF20A UHRF1 25402006 pred G G G G G G G G UBFD1 UHRF1 23023127 pred G G G G G G G G G G G G G G G UBE2I UHRF1 25402006, 23023127 pred G G G G G G G G G G G G G G G RRM2 UHRF1 25402006 pred G G G G G G G G G G G G G G G UBE2B UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 UBA2 23023127, 16082366 pred G G G G G G G G G G G G G G G LNX1 UHRF1 21836163 pred G G G G G G G G G G G G CIDEA UHRF1 23023127 pred G G G G G PTTG1 UHRF1 25402006 pred G G G G G G G G G G G G G G G MCM10 UHRF1 25402006 pred G G G HDAC3 UHRF1 25402006 pred G G G G G G G G G G G G G G G MEX3D UHRF1 23023127 pred G G G G G G G G G G G G G G BCL6 UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 FAM64A 25402006 pred G G G G G G G G G G G G G VEZF1 UHRF1 23023127 pred G G G G G G G G G G G G G G G TRIM73 UHRF1 23023127 pred G G G G G G G G G G G G G G UBE2C UHRF1 25402006, 23023127 pred G G G G G G G G G G G G G G G UHRF1 BAZ1A 23023127 pred G G G G G G G G G G G G G G G RNF20 UHRF1 21836163 pred G G G G G G G G G G G G G G G UHRF1 RAD18 23023127 pred G G EED UHRF1 25402006 pred G G G G G G G G G G G G G G G CEP55 UHRF1 25402006 pred G G G G G G G SUMO4 UHRF1 23023127 pred G G G G G G G G G G G G G G G RAF1 UHRF1 23023127 pred G G G G G G G G G G G G G G G RBBP4 UHRF1 25402006 pred G G G G G G G G G G G G G G G ZWINT UHRF1 25402006 pred G G G G G G G G G G G G G G G ESPL1 UHRF1 25402006 pred G G G G G G G G G G G G G G UHRF1 ANLN 25402006 pred G G G G G G G G NEK2 UHRF1 25402006 pred G G G G G G UBE2D3 UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 TMUB1 23023127 pred G G G G G G G G G G G G G G G AXIN1 UHRF1 23023127 pred G G G G G G G G G G G G G G MYLIP UHRF1 21836163 pred G G G G G G G G G G G G G G G TCEB2 UHRF1 23023127 pred G G G G G G G G G G G G G G G MIDN UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 NCAPG 25402006 pred G G G G G G G G G TRIP13 UHRF1 25402006 pred G G G G G G G G G G G G G G G DLGAP5 UHRF1 25402006 pred G G G G G UBE2A UHRF1 23023127 pred G G G G G G G G G G G G G G G MIB1 UHRF1 21836163 pred G G G G G G G G G G G G G G G UHRF1 FAM83D 25402006 pred G G G G G G G G G G G G G G G PJA1 UHRF1 21836163 pred G G G G G G G G G G G G G G G RAD23B UHRF1 23023127 pred G G G G G G G G G G G G G G G TP53 UHRF1 23023127 pred G G G G G G G G G G G G G G G HDAC2 UHRF1 25402006 pred G G G G G G G G G G G G G G G CHEK1 UHRF1 25402006 pred G G G G RBBP7 UHRF1 25402006 pred G G G G G G G G G G G G G G G UHRF1 NUF2 25402006 pred G G G UHRF1 UBE2D4 23023127 pred G G G G G G G G G G G G G G G MAD2L1 UHRF1 25402006 pred G G G G G G G G G G MYC UHRF1 25402006 pred G G G G G G G G G G G G G G H2AFZ UHRF1 25402006 pred G G G G G G G G G G G G G G G MELK UHRF1 25402006 pred G G G G G G G G G G G G UHRF1 DNMT3L 25402006 pred NFATC2IP UHRF1 23023127 pred G G G G G G G G G G G G G G G BRCA1 UHRF1 25402006, 23023127 pred G G G G MKI67 UHRF1 25402006 pred G G G G G G G G G G G G G G G SUMO2 UHRF1 23023127 pred G G G G G G G G G G G G G G G DVL2 UHRF1 23023127 pred G G G G G G G G G G G G G G G NRAS UHRF1 23023127 pred G G G G G G G G G G G G G G G GINS1 UHRF1 25402006 pred G G G G G G G G G G G G UBE2D1 UHRF1 23023127 pred G G G G G G G G G G G G G G G PIR51 UHRF1 25402006 pred G G G G G G G GATAD2B UHRF1 25402006 pred G G G G G G G G G G G G G G H3F3A, H3F3B UHRF1 25402006 pred G G G G G G G G G G G G G G G ISG15 UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 ASF1B 25402006 pred G G G G G G G G G G G G G G G MCM2 UHRF1 25402006 pred G G G G G G G G G G G G G G G VCP UHRF1 23023127 pred G G G G G G G G G G G G G G G CENPE UHRF1 25402006 pred G G G UHRF1 CDC6 25402006 pred G G G G G ARID4A UHRF1 25402006 pred G G G G G G G G UBE2D2 UHRF1 23023127 pred G G G G G G G G G G G G G G G ALDH3A1 UHRF1 21836163 pred G G G KIF11 UHRF1 25402006 pred G G G G G G HUS1 UHRF1 25402006 pred G G G G G G G G G G G G G CHD4 UHRF1 23023127 pred G G G G G G G G G G G G G G G UHRF1 TRAF6 23023127 pred G G G G G G G G G G G G G G G UBE3A UHRF1 21836163 pred G G G G G G G G G G G G G G G SMARCA5 UHRF1 25402006 pred G G G G G G G G G G G G G G G FOXM1 UHRF1 25402006 pred G G G G FAU UHRF1 23023127 pred G G G G G G G G G G G G G G G HCFC1 UHRF1 25402006 pred G G G G G G G G G G G G G G G SETDB1 UHRF1 25402006 pred G G G G G G G G G G G G G G G COL5A1 UHRF1 25402006 pred G G G G G G G G G G G G G G BAG6 UHRF1 23023127 pred G G G G G G G G G G G G G G G TMUB2 UHRF1 23023127 pred G G G G G G G G G G G G G G G RNF25 UHRF1 21836163 pred G CCNB1 UHRF1 25402006 pred G G G G G G G G G G G G G PRC1 UHRF1 25402006 pred G G G G G G G G G G G G G G G NONO UHRF1 23023127 pred G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96T88 Q96T88 - - - X 2 P04908 Q96T88 in vivo 14993289 - X 2 P04908 Q96T88 in vitro 14993289 - X 2 P04908 Q96T88 in vivo 14993289 - X 2 P04908 Q96T88 in vitro 14993289 - X 2 Q96T88 P68431 in vitro 14993289 - X 2 Q96T88 P68431 in vivo 14993289 - X 2 Q96T88 P68431 in vitro 14993289 - X 2 Q96T88 P68431 in vivo 14993289 - X 2 Q96T88 P33778 in vivo 14993289 - X 2 Q96T88 P33778 in vitro 14993289 - X 2 Q96T88 B2R4R0 in vivo 14993289 - X 2 Q96T88 B2R4R0 in vitro 14993289 - X 2 Q96T88 P33778 in vitro 14993289 - X 2 Q96T88 P33778 in vivo 14993289 - X 2 Q96T88 B2R4R0 in vivo 14993289 - X 2 Q96T88 B2R4R0 in vitro 14993289 - X 2 Q96T88 anti tag coimmunoprecipitation 19798101 physical association C 3 Q96T88 anti bait coimmunoprecipitation 19798101 physical association C 3 Q96T88 anti tag coimmunoprecipitation 19798101 physical association C 3 Q96T88 Q9Y6K1 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 Q9Y6K1 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 Q9Y6K1 fluorescence technology 19798101 physical association X 2 Q96T88 Q9Y6K1 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti bait coimmunoprecipitation 17934516 association C 3 Q96T88 anti tag coimmunoprecipitation 19615732 physical association C 15 Q96T88 P26358 two hybrid 17934516 physical association X 2 Q96T88 P26358 pull down 17934516 physical association X 2 Q96T88 P26358 confocal microscopy 17934516 colocalization X 2 Q96T88 P26358 confocal microscopy 17934516 colocalization X 2 Q96T88 Q9UBC3 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 Q9UBC3 fluorescence technology 19798101 physical association X 2 Q96T88 Q9UBC3 anti bait coimmunoprecipitation 19798101 physical association X 2 Q96T88 Q9UBC3 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 P26358 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 Q9UBC3 anti tag coimmunoprecipitation 19798101 physical association X 2 Q96T88 O88846 pull down 21252943 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B HIST1H2BB UHRF1 MI:0493(in vivo) 14993289 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_14558 - - PRKACA UHRF1 MI:0415(enzymatic study) 15178447 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_212220 bait prey ZNF259 UHRF1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_236893 prey bait USP7 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21268065,21745816,22411829,23297342,24013172 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_142241|BIOGRID_140772|BIOGRID_185247|BIOGRID_289228|BIOGRID_142243|BIOGRID_185240|BIOGRID_140764|BIOGRID_140766|BIOGRID_247869|BIOGRID_185244|BIOGRID_140774 prey|prey|bait|prey|bait|prey|bait|prey|prey|prey|bait bait|bait|prey|bait|prey|bait|prey|bait|bait|bait|prey HDAC1 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15361834,17934516,19800870,22411829 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_127584|BIOGRID_135017|BIOGRID_117845|BIOGRID_117846|BIOGRID_185243|BIOGRID_135015|UniProt_93158|UniProt_93157|UniProt_93156|UniProt_93154|UniProt_93155|UniProt_93152|UniProt_93153|UniProt_93151 prey|bait|prey|bait|prey|prey|prey|prey|prey|prey|bait|bait|prey|prey bait|prey|bait|prey|bait|bait|prey|bait|prey|bait|prey|prey|prey|bait RNF4 UHRF1 MI:0004(affinity chromatography technology) 21252943 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_183696 bait prey ELAVL1 UHRF1 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_186355 bait prey PML UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22945642 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_208786|BIOGRID_208785 bait|prey prey|bait SUMO2 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19471022,21252943 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_183986|BIOGRID_182994 bait|bait prey|prey HIST1H3A UHRF1 MI:0686(unspecified method)|MI:0493(in vivo) 14993289,22064703 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_181798|HPRD_11534 prey|- bait|- RB1 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16007129 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_213890|BIOGRID_213889 bait|prey prey|bait SUV39H1 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22330138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_191774|BIOGRID_191772 bait|prey prey|bait USP11 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22411829 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_185249|BIOGRID_185248|BIOGRID_185241 prey|bait|prey bait|prey|bait CUL1 UHRF1 MI:0004(affinity chromatography technology) 23297342 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_247872 prey bait KAT5 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19800870,21045206,23677994 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_280970|BIOGRID_149337|BIOGRID_280971|BIOGRID_127582 prey|bait|prey|prey bait|prey|bait|bait HIST2H3A; UHRF1 MI:0114(x-ray crystallography)|MI:0686(unspecified method)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography) 21489993,22294699,22837395,23022729 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_210360|BIOGRID_218659|BIOGRID_197485|BIOGRID_210355|BIOGRID_210358|BIOGRID_210359|BIOGRID_192227|BIOGRID_210356|BIOGRID_210357 prey|prey|prey|prey|prey|prey|bait|prey|prey bait|bait|bait|bait|bait|bait|prey|bait|bait UHRF1 DNMT3A MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0686(unspecified method)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19798101,21745816,22064703 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) UniProt_103561|MINT_44107|UniProt_103560|MINT_74394|MINT_44103|MINT_74390|UniProt_103554|UniProt_103562|UniProt_103564|MINT_74399|MINT_74397|UniProt_103558|MINT_74391|UniProt_103555|MINT_44104|MINT_74401|MINT_44109|BIOGRID_127555|BIOGRID_127557|BIOGRID_140769|MINT_44111|BIOGRID_181802|MINT_44113|MINT_44108|MINT_74395 bait|bait|bait|bait|bait|bait|bait|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|bait|bait prey|prey|prey|prey|prey|prey|prey|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|prey|prey HIST1H4A UHRF1 MI:0493(in vivo) 14993289 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_14560 - - DNMT1 UHRF1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0686(unspecified method)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 17673620,17934516,19798101,19800870,19943104,20613874,21045206,21268065,21745816,22064703,24368767 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint) UniProt_93158|UniProt_93157|UniProt_93156|UniProt_93154|UniProt_93155|UniProt_93152|UniProt_93153|UniProt_93151|UniProt_103561|UniProt_93149|BIOGRID_218667|BIOGRID_140773|BIOGRID_140771|BIOGRID_198708|BIOGRID_198709|BIOGRID_218669|UniProt_93160|BIOGRID_127583|UniProt_93159|BIOGRID_181800|UniProt_103557|MINT_74393|MINT_44106|BIOGRID_140762|BIOGRID_126379|BIOGRID_142244|BIOGRID_149332|BIOGRID_149331|BIOGRID_117843|BIOGRID_117842|BIOGRID_140767|BIOGRID_117844|UniProt_93150|BIOGRID_307797|BIOGRID_117848|MINT_44108|MINT_74395 bait|prey|bait|prey|prey|prey|bait|prey|prey|prey|bait|prey|bait|bait|bait|prey|neutral component|prey|neutral component|bait|bait|bait|bait|bait|bait|prey|prey|bait|prey|prey|prey|prey|bait|prey|bait|prey|prey prey|bait|prey|bait|prey|prey|prey|bait|bait|bait|prey|bait|prey|prey|prey|bait|neutral component|bait|neutral component|prey|prey|prey|prey|prey|prey|bait|bait|prey|bait|bait|bait|bait|prey|bait|prey|bait|bait UHRF1 BTRC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23297342 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_247871|BIOGRID_247870|BIOGRID_247873 prey|bait|prey bait|prey|bait HDAC2 UHRF1 MI:0004(affinity chromatography technology) 15361834 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_135016 prey bait UBC UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17370265,18781797,21139048,21890473,21906983,21963094,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_268760|BIOGRID_264976|BIOGRID_223983|BIOGRID_162264|BIOGRID_171017|BIOGRID_161301|BIOGRID_180227|BIOGRID_175911 bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey MPG UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23537643 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_272966|BIOGRID_273001|BIOGRID_273002 bait|bait|prey prey|prey|bait EZH2 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22330138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_191773|BIOGRID_191771 bait|prey prey|bait HIST1H2AB UHRF1 MI:0493(in vivo) 14993289 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_14559 - - UHRF2 UHRF1 MI:0004(affinity chromatography technology) 22411829 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_185242 prey bait HIST3H3 UHRF1 MI:0096(pull down)|MI:0096(pull down)|MI:0686(unspecified method)|MI:0096(pull down)|MI:0686(unspecified method)|MI:0096(pull down) 22100450,23161542,23281010,23752590 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_212799|BIOGRID_212798|BIOGRID_281228|BIOGRID_247365|BIOGRID_249537|BIOGRID_247364 prey|prey|prey|prey|bait|prey bait|bait|bait|bait|prey|bait TRIM28 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22055183 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_182161|BIOGRID_182160 prey|bait bait|prey UHRF1BP1 UHRF1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15361834 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_135022|BIOGRID_135020|BIOGRID_135021 bait|prey|prey prey|bait|bait EHMT2 UHRF1 MI:0428(imaging technique)|MI:0686(unspecified method)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19056828,19943104,22064703 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_126378|BIOGRID_181806|BIOGRID_127611|BIOGRID_127610 bait|bait|prey|bait prey|prey|bait|prey SUZ12 UHRF1 MI:0004(affinity chromatography technology) 22330138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191770 prey bait UHRF1 DNMT3B MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0686(unspecified method)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19798101,22064703 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_103563|MINT_74398|MINT_74389|UniProt_103559|UniProt_103566|UniProt_103565|UniProt_103556|MINT_74392|MINT_74403|MINT_44115|MINT_44105|MINT_74400|BIOGRID_127556|MINT_44110|BIOGRID_127558|MINT_44112|MINT_44102|BIOGRID_181804|MINT_44107|UniProt_103560|MINT_74394|MINT_44103|MINT_74390|UniProt_103554 prey|prey|bait|prey|bait|prey|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|bait|prey|bait|bait|bait|bait|bait|bait bait|bait|prey|bait|prey|bait|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|prey|bait|prey|prey|prey|prey|prey|prey UHRF1 RNF2 MI:0004(affinity chromatography technology) 24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_306937 prey bait

PPI - HINT Gene A Gene B PMID Method Quality ZPR1 UHRF1 22939629 0401 HT CCNDBP1 UHRF1 26186194 0004 HT PCNA UHRF1 26496610,26496610 0007,0004 HT UQCRB UHRF1 26186194 0004 HT DNMT1 UHRF1 17673620,17934516,19798101,17934516,19943104,21045206,19800870,21745816,17934516,17934516,17673620,21745816,22064703,17934516 0096,0006,0007,0018,0428,0004,0004,0004,0663,0004,0004,0096,0004,0096 LC RPL10 UHRF1 26496610,26496610 0007,0004 HT HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J UHRF1 25281560 1313 LC HNRNPU UHRF1 26496610 0007 HT HDAC1 UHRF1 19800870,17934516,15361834,17934516,22411829 0004,0004,0004,0006,0004 LC TCEAL1 UHRF1 26186194,19615732 0004,0007 HT DBN1 UHRF1 26496610,26496610 0007,0004 HT HIST3H3 UHRF1 23161542,22100450,22100450,23161542 0114,0114,0096,0096 LC Q59FP7 UHRF1 24368767,24782312,21745816,24782312,17934516,19943104,21045206,19800870,21745816,17673620,17934516,17673620,20613874,26065575,22064703,17934516 0096,0004,0096,0415,0018,0428,0004,0004,0004,0096,0004,0004,0004,0004,0004,0096 LC WIPI1 UHRF1 26186194 0004 HT HIST2H3A|HIST2H3C|HIST2H3D UHRF1 22294699 0004 LC KAT5 UHRF1 23677994,23677994,19800870,21045206 0004,0096,0004,0004 LC USP7 UHRF1 26046769,21745816,26496610,23297342,26299963,26496610,26046769,22411829,21745816,26299963,21268065,21268065,24013172,26299963 0004,0096,0004,0004,0004,0007,0096,0004,0004,0096,0415,0004,0004,0114 LC,HT Q96BA7 UHRF1 26496610 0004 HT EHMT2 UHRF1 19943104,19056828,22064703 0428,0004,0004 LC UHRF1 TRPV5 26186194 0004 HT UHRF1 DNMT3B 19798101,19798101,19798101,19798101,22064703 0007,0006,0051,0004,0004 LC UHRF1 BTRC 23297342,23297342,26768845 0415,0004,0004 LC UHRF1 DNMT3A 19798101,19798101,19798101,19798101,21745816,22064703 0004,0007,0006,0051,0096,0004 LC ZPR1 UHRF1 22939629 0401 HT CCNDBP1 UHRF1 26186194 0004 HT PCNA UHRF1 26496610,26496610 0007,0004 HT UQCRB UHRF1 26186194 0004 HT RPL10 UHRF1 26496610,26496610 0007,0004 HT HNRNPU UHRF1 26496610 0007 HT TCEAL1 UHRF1 26186194,19615732 0004,0007 HT DBN1 UHRF1 26496610,26496610 0007,0004 HT WIPI1 UHRF1 26186194 0004 HT USP7 UHRF1 26496610,26496610 0004,0007 HT Q96BA7 UHRF1 26496610 0004 HT UHRF1 TRPV5 26186194 0004 HT DNMT1 UHRF1 17673620,17934516,19798101,17934516,19943104,21045206,19800870,21745816,17934516,17934516,17673620,21745816,22064703,17934516 0096,0006,0007,0018,0428,0004,0004,0004,0663,0004,0004,0096,0004,0096 LC HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J UHRF1 25281560 1313 LC HDAC1 UHRF1 19800870,17934516,15361834,17934516,22411829 0004,0004,0004,0006,0004 LC HIST3H3 UHRF1 23161542,22100450,22100450,23161542 0114,0114,0096,0096 LC Q59FP7 UHRF1 24368767,24782312,21745816,24782312,17934516,19943104,21045206,19800870,21745816,17673620,17934516,17673620,20613874,26065575,22064703,17934516 0096,0004,0096,0415,0018,0428,0004,0004,0004,0096,0004,0004,0004,0004,0004,0096 LC HIST2H3A|HIST2H3C|HIST2H3D UHRF1 22294699 0004 LC KAT5 UHRF1 23677994,23677994,19800870,21045206 0004,0096,0004,0004 LC USP7 UHRF1 26046769,21745816,23297342,26299963,26046769,22411829,21745816,26299963,21268065,21268065,24013172,26299963 0004,0096,0004,0004,0096,0004,0004,0096,0415,0004,0004,0114 LC EHMT2 UHRF1 19943104,19056828,22064703 0428,0004,0004 LC UHRF1 DNMT3B 19798101,19798101,19798101,19798101,22064703 0007,0006,0051,0004,0004 LC UHRF1 BTRC 23297342,23297342,26768845 0415,0004,0004 LC UHRF1 DNMT3A 19798101,19798101,19798101,19798101,21745816,22064703 0004,0007,0006,0051,0096,0004 LC ZPR1 UHRF1 22939629 0401 LC PRKACA UHRF1 15178447 0415 LC DNMT1 UHRF1 17934516,17934516,17934516,17934516,21268065,17934516 0006,0018,0663,0004,0415,0096 LC HIST1H3A|HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST1H3G|HIST1H3H|HIST1H3I|HIST1H3J UHRF1 22096602,17967883 0114,0415 LC H3F3A|H3F3B UHRF1 22837395 0114 LC HIST3H3 UHRF1 23161542,22100450,22100450,23161542 0114,0114,0096,0096 LC Q53GA5 UHRF1 26102039,26102039,26102039 0096,0004,0415 LC Q59FP7 UHRF1 24782312,24782312,17934516,17934516,21268065,17934516 0004,0415,0018,0004,0415,0096 LC HIST2H3A|HIST2H3C|HIST2H3D UHRF1 21489993,22837395 0114,0114 LC USP7 UHRF1 26299963,26299963,21268065,21268065,26299963 0004,0096,0415,0004,0114 LC UHRF1 UHRF1 26299963,PDB_4QQD,21777816,PDB_2FAZ,22096602,22100450,23161542,18772889,17967883,24782312 0415,0114,0114,0114,0114,0114,0415,0114,0415,0415 LC UHRF1 DNMT3B 19798101,19798101,19798101,19798101 0007,0006,0051,0004 LC UHRF1 BTRC 23297342,23297342 0415,0004 LC UHRF1 DNMT3A 19798101,19798101,19798101,19798101 0004,0007,0006,0051 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96T88 Q5MNZ9 UHRF1 WIPI1 0.126 26186194 Q9NQA5 Q96T88 TRPV5 UHRF1 0.126 26186194 Q9H0W5 Q96T88 CCDC8 UHRF1 0.126 24711643 Q9Z2D7 Q96T88 MBD4 UHRF1 0.21 25358258 Q96T88 O75147 UHRF1 OBSL1 0.126 24711643 Q96T88 P07992 UHRF1 ERCC1 0.569 25818288 Q96T88 Q71DI3 UHRF1 HIST2H3D 0.82 21489993,22837395,23022729,22294699 Q96T88 O88846 UHRF1 RNF4 0.21 21252943 Q96T88 O95273 UHRF1 CCNDBP1 0.126 26186194 Q96T88 O95433 UHRF1 AHSA1 0.126 26693507 Q96T88 P04629 UHRF1 NTRK1 0.126 25921289 Q96T88 P04637 UHRF1 TP53 0.74 26102039 Q96T88 P09874 UHRF1 PARP1 0.454 24782312 Q96T88 Q8R023 UHRF1 PCGF1 0.236 26496610 Q96T88 O95243 UHRF1 MBD4 0.702 25358258 Q96T88 P11388 UHRF1 TOP2A 0.454 25451918 Q96T88 Q92993 UHRF1 KAT5 0.731 21045206,19800870,23677994 Q9Y297 Q96T88 BTRC UHRF1 0.731 26768845,23297342 Q96T88 Q16643 UHRF1 DBN1 0.236 26496610 Q96T88 P12004 UHRF1 PCNA 0.236 26496610 Q96T88 Q16695 UHRF1 HIST3H3 0.964 24813945,23281010,26065575,22100450,23161542,23752590 Q99PL5 Q96T88 RRBP1 UHRF1 0.236 26496610 Q96T88 Q15170 UHRF1 TCEAL1 0.236 19615732,26186194 Q96T88 Q00839 UHRF1 HNRNPU 0.236 26496610 Q96T88 P27635 UHRF1 RPL10 0.236 26496610 Q96T88 Q6ZWV7 UHRF1 RPL35 0.236 26496610 Q96T88 Q13547 UHRF1 HDAC1 0.848 22411829,19800870,15361834,17934516 Q9UBC3 Q96T88 DNMT3B UHRF1 0.848 19798101,22064703 Q9Y6K1 Q96T88 DNMT3A UHRF1 0.867 19798101,21745816,22064703 Q96T88 Q96T88 UHRF1 UHRF1 0.801 26299963,23161542,24782312,17967883 Q96T88 Q93009 UHRF1 USP7 0.99 26299963,21745816,21268065,23297342,24013172,22411829,26046769,26496610 Q96T88 P26358 UHRF1 DNMT1 1 19798101,19800870,17934516,24782312,24368767,26065575,19943104,21745816,21268065,20613874,21045206,22064703,17673620 Q96T88 P29372 UHRF1 MPG 0.376 23537643 Q96T88 Q96NY9 UHRF1 MUS81 0.569 25818288 Q96T88 P61077 UHRF1 UBE2D3 0.309 26299963 Q96T88 O14744 UHRF1 PRMT5 0.376 26597461 Q96T88 O43463 UHRF1 SUV39H1 0.376 22330138 Q96T88 O75312 UHRF1 ZPR1 0.081 22939629 Q96T88 P51784 UHRF1 USP11 0.376 22411829 Q96T88 P06400 UHRF1 RB1 0.376 16007129 Q96T88 Q6BDS2 UHRF1 UHRF1BP1 0.376 15361834 Q96T88 Q13263 UHRF1 TRIM28 0.376 22055183 Q96T88 Q13616 UHRF1 CUL1 0.21 23297342 Q96T88 Q15022 UHRF1 SUZ12 0.21 22330138 Q96T88 Q15910 UHRF1 EZH2 0.376 22330138 Q96T88 Q92889 UHRF1 ERCC4 0.21 25818288 Q96T88 Q96PU4 UHRF1 UHRF2 0.21 22411829 Q96T88 Q96AY2 UHRF1 EME1 0.21 25818288 Q96T88 Q96KQ7 UHRF1 EHMT2 0.569 19943104,19056828,22064703 Q9UKB1 Q96T88 FBXW11 UHRF1 0.376 26768845 Q99496 Q96T88 RNF2 UHRF1 0.126 24457600 Q9UGN5 Q96T88 PARP2 UHRF1 0.21 24782312 Q96T88 P17612 UHRF1 PRKACA 0.309 15178447 Q96T88 P78317 UHRF1 RNF4 0.21 21252943 Q96T88 P62807 UHRF1 HIST1H2BI 0.126 25281560 Q96T88 F8VQC1 UHRF1 F8VQC1 0.126 26496610 Q96T88 P14927 UHRF1 UQCRB 0.126 26186194 Q96T88 Q15717 UHRF1 ELAVL1 0.126 19322201 Q96T88 Q13469 UHRF1 NFATC2 0.126 27637333 Q96T88 P68431 UHRF1 HIST1H3J 0.583 25281560,17967883,22064703

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SUV39H1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BK UHRF1 MI:0362 inference MI:0461 interaction database OBSL1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database SRP72 UHRF1 MI:0362 inference MI:0461 interaction database MBD4 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database CCNDBP1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database AHSA1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database NTRK1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database TP53 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AB UHRF1 MI:0362 inference MI:0461 interaction database RB1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BJ UHRF1 MI:0362 inference MI:0461 interaction database ERCC1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database PARP1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database H2AFZ UHRF1 MI:0362 inference MI:0461 interaction database HIST1H2AG UHRF1 MI:0362 inference MI:0461 interaction database UBC UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database TOP2A UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database PCNA UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database UQCRB UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database H2AFX UHRF1 MI:0362 inference MI:0461 interaction database PRKACA UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database RCC1 UHRF1 MI:0362 inference MI:0461 interaction database HIST1H2AD UHRF1 MI:0362 inference MI:0461 interaction database TAF1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BO UHRF1 MI:0362 inference MI:0461 interaction database LMO2 UHRF1 MI:0362 inference MI:0461 interaction database DNMT1 UHRF1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RPL10 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database MPG UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database PML UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BB UHRF1 MI:0362 inference MI:0461 interaction database RPL35 UHRF1 MI:0362 inference MI:0461 interaction database USP11 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO3 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BD UHRF1 MI:0362 inference MI:0461 interaction database UBE2D3 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database SUMO2 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H4A UHRF1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database HIST1H2BC UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H3A UHRF1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF4 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database H3F3A UHRF1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HNRNPU UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H1A UHRF1 MI:0362 inference MI:0461 interaction database TOP2B UHRF1 MI:0362 inference MI:0461 interaction database TRIM28 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database ATM UHRF1 MI:0362 inference MI:0461 interaction database HDAC1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database CUL1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database SUZ12 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database TCEAL1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database EZH2 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database DBN1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST3H3 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2AC UHRF1 MI:0362 inference MI:0461 interaction database HIST2H2BE UHRF1 MI:0362 inference MI:0461 interaction database WIPI1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1BP1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST2H2AA3 UHRF1 MI:0362 inference MI:0461 interaction database H3F3C UHRF1 MI:0362 inference MI:0461 interaction database HIST2H3A UHRF1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HIST3H2A UHRF1 MI:0362 inference MI:0461 interaction database HIST2H2AB UHRF1 MI:0362 inference MI:0461 interaction database HIST3H2BB UHRF1 MI:0362 inference MI:0461 interaction database HDAC2 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database ERCC4 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database KAT5 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database USP7 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AC UHRF1 MI:0362 inference MI:0461 interaction database HIST1H2BH UHRF1 MI:0362 inference MI:0461 interaction database HIST1H2BA UHRF1 MI:0362 inference MI:0461 interaction database EME1 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AH UHRF1 MI:0362 inference MI:0461 interaction database EHMT2 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database MUS81 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database UHRF2 UHRF1 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2AA UHRF1 MI:0362 inference MI:0461 interaction database UHRF1 RNF2 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 HIST1H2BN MI:0362 inference MI:0461 interaction database UHRF1 HIST1H2AJ MI:0362 inference MI:0461 interaction database UHRF1 HIST1H2BM MI:0362 inference MI:0461 interaction database UHRF1 HIST1H2BL MI:0362 inference MI:0461 interaction database UHRF1 PCGF1 MI:0362 inference MI:0461 interaction database UHRF1 H2AFJ MI:0362 inference MI:0461 interaction database UHRF1 CCDC8 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 NANOG MI:0362 inference MI:0461 interaction database UHRF1 TRPV5 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 RRBP1 MI:0362 inference MI:0461 interaction database UHRF1 DNMT3B MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 PARP2 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 BTRC MI:0045 experimental interaction detection MI:0461 interaction database UHRF1 SUPT16H MI:0362 inference MI:0461 interaction database UHRF1 DNMT3A MI:0045 experimental interaction detection MI:0461 interaction database